TreeWAS – Variant ID: rs10492972

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I85.9 Oesophageal varices without bleeding	0.083	0.917	0.000
I85 Oesophageal varices	0.050	0.950	0.000
I85.0 Oesophageal varices with bleeding	0.044	0.956	0.000
I31.3 Pericardial effusion (noninflammatory)	0.021	0.979	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.981	0.019
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.010	0.990	0.000
Z45.2 Adjustment and management of vascular access device	0.007	0.993	0.000
Q51.3 Bicornate uterus	0.007	0.993	0.000
Q51 Congenital malformations of uterus and cervix	0.006	0.994	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.006	0.994	0.000
Q51.2 Other doubling of uterus	0.006	0.994	0.000
N42.8 Other specified disorders of prostate	0.000	0.994	0.006
Q50.4 Embryonic cyst of Fallopian tube	0.006	0.994	0.000
Z03.1 Observation for suspected malignant neoplasm	0.000	0.994	0.006
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.005	0.995	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.005	0.995	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.995	0.005
Q50.5 Embryonic cyst of broad ligament	0.005	0.995	0.000
C92 Myeloid leukaemia	0.000	0.995	0.005
Q50-Q56 Congenital malformations of genital organs	0.005	0.995	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.005	0.995	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.005	0.995	0.000
Q51.6 Embryonic cyst of cervix	0.005	0.995	0.000
Q51.5 Agenesis and aplasia of cervix	0.005	0.995	0.000
Q51.0 Agenesis and aplasia of uterus	0.005	0.995	0.000
Q51.4 Unicornate uterus	0.005	0.995	0.000
I31 Other diseases of pericardium	0.005	0.995	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.996	0.004
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.996	0.004
Q51.8 Other congenital malformations of uterus and cervix	0.004	0.996	0.000
I44.1 Atrioventricular block, second degree	0.000	0.996	0.004
Q43.8 Other specified congenital malformations of intestine	0.004	0.996	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.004	0.996	0.000
Q50.3 Other congenital malformations of ovary	0.004	0.996	0.000
Q50.2 Congenital torsion of ovary	0.004	0.996	0.000
Q50.1 Developmental ovarian cyst	0.004	0.996	0.000
Q50.0 Congenital absence of ovary	0.004	0.996	0.000
Q43.0 Meckel's diverticulum	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
Q52 Other congenital malformations of female genitalia	0.004	0.996	0.000
C92.9 Myeloid leukaemia, unspecified	0.000	0.996	0.004
Q43.9 Congenital malformation of intestine, unspecified	0.004	0.996	0.000
D37.5 Rectum	0.000	0.996	0.004
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.996	0.004
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.996	0.004
C92.5 Acute myelomonocytic leukaemia	0.000	0.996	0.004
C92.4 Acute promyelocytic leukaemia	0.000	0.996	0.004
C92.3 Myeloid sarcoma	0.000	0.996	0.004
C92.2 Subacute myeloid leukaemia	0.000	0.996	0.004
Q56 Indeterminate sex and pseudohermaphroditism	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
N42 Other disorders of prostate	0.000	0.996	0.004
I31.0 Chronic adhesive pericarditis	0.003	0.996	0.000
I31.8 Other specified diseases of pericardium	0.003	0.996	0.000
I31.2 Haemopericardium, not elsewhere classified	0.003	0.996	0.000
C92.7 Other myeloid leukaemia	0.000	0.996	0.003
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.996	0.000
Q53 Undescended testicle	0.003	0.996	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.997	0.003
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.997	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q52.5 Fusion of labia	0.003	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
I31.1 Chronic constrictive pericarditis	0.003	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.003	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
Q52.3 Imperforate hymen	0.003	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.997	0.000
Q52.1 Doubling of vagina	0.003	0.997	0.000
Q52.0 Congenital absence of vagina	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
N42.0 Calculus of prostate	0.000	0.997	0.003
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.997	0.003
Q56.4 Indeterminate sex, unspecified	0.003	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
E53.8 Deficiency of other specified B group vitamins	0.003	0.997	0.000
N42.2 Atrophy of prostate	0.000	0.997	0.003
Q39.4 Oesophageal web	0.003	0.997	0.000
C18.0 Caecum	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
N42.3 Dysplasia of prostate	0.000	0.997	0.003
Q44.6 Cystic disease of liver	0.003	0.997	0.000
D39.1 Ovary	0.003	0.997	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.997	0.003
H21.8 Other specified disorders of iris and ciliary body	0.000	0.997	0.003
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
D37.4 Colon	0.000	0.997	0.003
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.003	0.997	0.000
Q53.0 Ectopic testis	0.003	0.997	0.000
C21.1 Anal canal	0.003	0.997	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.997	0.003
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.997	0.003
C21.0 Anus, unspecified	0.003	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.997	0.000
Q40.1 Congenital hiatus hernia	0.002	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.997	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.997	0.003
C51.9 Vulva, unspecified	0.003	0.997	0.000
M75.3 Calcific tendinitis of shoulder	0.003	0.997	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.997	0.000
Z34.8 Supervision of other normal pregnancy	0.003	0.997	0.000
S27.0 Traumatic pneumothorax	0.000	0.997	0.002
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.003
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.003
Q53.1 Undescended testicle, unilateral	0.002	0.997	0.000
Q38.1 Ankyloglossia	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.998	0.002
D37.6 Liver, gallbladder and bile ducts	0.000	0.998	0.002
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.998	0.000
Z45 Adjustment and management of implanted device	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.998	0.000
Q38.2 Macroglossia	0.002	0.998	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
Z04.8 Examination and observation for other specified reasons	0.002	0.998	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.998	0.002
Z45.1 Adjustment and management of infusion pump	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.002
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
C24.1 Ampulla of Vater	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
L25.9 Unspecified contact dermatitis, unspecified cause	0.002	0.998	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.998	0.002
D37.3 Appendix	0.000	0.998	0.002
F05.9 Delirium, unspecified	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
C21 Malignant neoplasm of anus and anal canal	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.998	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.998	0.002
K22.9 Disease of oesophagus, unspecified	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.002
R23.4 Changes in skin texture	0.000	0.998	0.002
Z35 Supervision of high-risk pregnancy	0.000	0.998	0.002
Z45.9 Adjustment and management of unspecified implanted device	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.002	0.998	0.000
D37.2 Small intestine	0.000	0.998	0.002
M40.24 Other and unspecified kyphosis (Thoracic region)	0.002	0.998	0.000
Z45.3 Adjustment and management of implanted hearing device	0.002	0.998	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
C24.9 Biliary tract, unspecified	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
D37.9 Digestive organ, unspecified	0.000	0.998	0.002
D37.7 Other digestive organs	0.000	0.998	0.002
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.998	0.002
Z45.8 Adjustment and management of other implanted devices	0.002	0.998	0.000
Q54.8 Other hypospadias	0.001	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
C21.2 Cloacogenic zone	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
H18.3 Changes in corneal membranes	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
F60.6 Anxious [avoidant] personality disorder	0.002	0.998	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.998	0.002
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
Z35.8 Supervision of other high-risk pregnancies	0.000	0.998	0.002
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.998	0.002
Z35.6 Supervision of very young primigravida	0.000	0.998	0.002
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.998	0.002
F01.9 Vascular dementia, unspecified	0.002	0.998	0.000
F22.0 Delusional disorder	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.000	0.998	0.002
Q54.1 Hypospadias, penile	0.001	0.998	0.000
Z71.9 Counselling, unspecified	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.000	0.998	0.002
D39.7 Other female genital organs	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
D37.0 Lip, oral cavity and pharynx	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.998	0.002
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.000	0.998	0.002
I37.1 Pulmonary valve insufficiency	0.000	0.998	0.002
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.001	0.998	0.000
D76.3 Other histiocytosis syndromes	0.000	0.998	0.002
F11.2 Dependence syndrome	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.001	0.998	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.001	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.001	0.998	0.000
H21.0 Hyphaema	0.000	0.998	0.001
S91.0 Open wound of ankle	0.000	0.998	0.001
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
C50.2 Upper-inner quadrant of breast	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.001
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.998	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.998	0.001
Q54.0 Hypospadias, balanic	0.001	0.998	0.001
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.999	0.000
Q54.9 Hypospadias, unspecified	0.001	0.999	0.000
Q63.0 Accessory kidney	0.001	0.999	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.999	0.001
S91.2 Open wound of toe(s) with damage to nail	0.000	0.999	0.001
M66.09 Rupture of popliteal cyst-Site unspec	0.001	0.999	0.000
M66.08 Rupture of popliteal cyst-Other	0.001	0.999	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.001	0.999	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.001	0.999	0.000
M66.04 Rupture of popliteal cyst-Hand	0.001	0.999	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.001	0.999	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.001	0.999	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.001	0.999	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.000	0.999	0.001
M40.2 Other and unspecified kyphosis	0.001	0.999	0.000
M40.22 Other and unspecified kyphosis (Cervical region)	0.001	0.999	0.000
C24.8 Overlapping lesion of biliary tract	0.001	0.999	0.000
C24.0 Extrahepatic bile duct	0.001	0.999	0.000
D39.9 Female genital organ, unspecified	0.001	0.999	0.000
D39.2 Placenta	0.001	0.999	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.999	0.000
H21.4 Pupillary membranes	0.000	0.999	0.001
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.001	0.999	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.999	0.001
Z90.3 Acquired absence of part of stomach	0.001	0.999	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.001	0.999	0.000
D44.0 Thyroid gland	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.999	0.001
D37.1 Stomach	0.000	0.999	0.001
Q63.2 Ectopic kidney	0.001	0.999	0.000
H18 Other disorders of cornea	0.001	0.999	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.001	0.999	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.001	0.999	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.001	0.999	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.001	0.999	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.001	0.999	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.001	0.999	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.001	0.999	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.001	0.999	0.000
H69.8 Other specified disorders of Eustachian tube	0.001	0.999	0.000
H18.5 Hereditary corneal dystrophies	0.001	0.999	0.000
T36.0 Penicillins	0.001	0.999	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.999	0.001
H11.9 Disorder of conjunctiva, unspecified	0.001	0.999	0.000
K55.1 Chronic vascular disorders of intestine	0.001	0.999	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.999	0.001
B02.3 Zoster ocular disease	0.000	0.999	0.001
D73.0 Hyposplenism	0.000	0.999	0.001
S92.40 Fracture of great toe (closed)	0.000	0.999	0.001
B37.3 Candidiasis of vulva and vagina	0.001	0.999	0.000
O46.8 Other antepartum haemorrhage	0.001	0.999	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.999	0.001
T78.3 Angioneurotic oedema	0.000	0.999	0.001
K86 Other diseases of pancreas	0.000	0.999	0.001
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M40.27 Other and unspecified kyphosis (Lumbosacral region)	0.001	0.999	0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.001	0.999	0.000
M40.23 Other and unspecified kyphosis (Cervicothoracic region)	0.001	0.999	0.000
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M40.20 Other and unspecified kyphosis (Multiple sites in spine)	0.001	0.999	0.000
H18.2 Other corneal oedema	0.001	0.999	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.999	0.001
R59.0 Localised enlarged lymph nodes	0.001	0.999	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.999	0.001
H69 Other disorders of Eustachian tube	0.001	0.999	0.000
D39.0 Uterus	0.001	0.999	0.000
G45.4 Transient global amnesia	0.000	0.999	0.001
Q38.7 Pharyngeal pouch	0.001	0.999	0.001
T91.3 Sequelae of injury of spinal cord	0.000	0.999	0.001
G54.0 Brachial plexus disorders	0.001	0.999	0.000
H18.7 Other corneal deformities	0.001	0.999	0.000
K38.9 Disease of appendix, unspecified	0.000	0.999	0.001
M23.5 Chronic instability of knee	0.000	0.999	0.001
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.999	0.001
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.001	0.999	0.000
H18.6 Keratoconus	0.001	0.999	0.000
L03.3 Cellulitis of trunk	0.001	0.999	0.000
M40.26 Other and unspecified kyphosis (Lumbar region)	0.001	0.999	0.000
H53.0 Amblyopia ex anopsia	0.000	0.999	0.001
O63.0 Prolonged first stage (of labour)	0.000	0.999	0.001
Q63 Other congenital malformations of kidney	0.001	0.999	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.001	0.999	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.999	0.001
H18.0 Corneal pigmentations and deposits	0.001	0.999	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.999	0.001
R16.0 Hepatomegaly, not elsewhere classified	0.001	0.999	0.000
R41.0 Disorientation, unspecified	0.001	0.999	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.001	0.999	0.000
B37.9 Candidiasis, unspecified	0.001	0.999	0.000
H06.2 Dysthyroid exophthalmos	0.000	0.999	0.001
H69.0 Patulous Eustachian tube	0.001	0.999	0.000
M65.1 Other infective (teno)synovitis	0.001	0.999	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.001	0.999	0.000
R60.1 Generalised oedema	0.000	0.999	0.001
Z98.8 Other specified postsurgical states	0.001	0.999	0.000
E53 Deficiency of other B group vitamins	0.001	0.999	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.999	0.001
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.999	0.001
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.999	0.001
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.999	0.001
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.999	0.001
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.999	0.001
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.999	0.001
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.999	0.001
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.999	0.001
L05.0 Pilonidal cyst with abscess	0.001	0.999	0.000
S93.0 Dislocation of ankle joint	0.000	0.999	0.001
Q89 Other congenital malformations, not elsewhere classified	0.000	0.999	0.001
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.001	0.999	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.001	0.999	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.001	0.999	0.000
H61.8 Other specified disorders of external ear	0.001	0.999	0.000
K72.9 Hepatic failure, unspecified	0.000	0.999	0.001
M66.4 Spontaneous rupture of other tendons	0.001	0.999	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.999	0.001
Q63.8 Other specified congenital malformations of kidney	0.001	0.999	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.999	0.001
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.999	0.001
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.999	0.001
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.999	0.001
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.999	0.001
M66 Spontaneous rupture of synovium and tendon	0.001	0.999	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.999	0.001
A87.9 Viral meningitis, unspecified	0.000	0.999	0.001
C83.7 Burkitt's tumour	0.001	0.999	0.000
D23.5 Skin of trunk	0.000	0.999	0.001
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.999	0.001
M66.5 Spontaneous rupture of unspecified tendon	0.001	0.999	0.000
M66.3 Spontaneous rupture of flexor tendons	0.001	0.999	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.999	0.001
Q63.3 Hyperplastic and giant kidney	0.001	0.999	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.001	0.999	0.000
K86.3 Pseudocyst of pancreas	0.000	0.999	0.001
Q79.6 Ehlers-Danlos syndrome	0.000	0.999	0.001
Y57.8 Other drugs and medicaments	0.001	0.999	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.001	0.999	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.999	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.001	0.999	0.000
M65.18 Other infective (teno)synovitis (Other)	0.001	0.999	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.001	0.999	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.001	0.999	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.001	0.999	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.001	0.999	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.001	0.999	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.001	0.999	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.001	0.999	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.001	0.999	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.999	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.999	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.999	0.001
C83.0 Small cell (diffuse)	0.001	0.999	0.000
E53.1 Pyridoxine deficiency	0.001	0.999	0.000
E53.0 Riboflavin deficiency	0.001	0.999	0.000
H18.1 Bullous keratopathy	0.001	0.999	0.000
Q89.9 Congenital malformation, unspecified	0.000	0.999	0.001
Q89.8 Other specified congenital malformations	0.000	0.999	0.001
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.999	0.001
Q89.4 Conjoined twins	0.000	0.999	0.001
Q89.3 Situs inversus	0.000	0.999	0.001
Q89.1 Congenital malformations of adrenal gland	0.000	0.999	0.001
Q89.0 Congenital malformations of spleen	0.000	0.999	0.001
S01.1 Open wound of eyelid and periocular area	0.000	0.999	0.001
S99 Other and unspecified injuries of ankle and foot	0.000	0.999	0.001
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.001	0.999	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.001	0.999	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.001	0.999	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.001	0.999	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.001	0.999	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.001	0.999	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.001	0.999	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.001	0.999	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.001	0.999	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.001	0.999	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.001	0.999	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.001	0.999	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.001	0.999	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.001	0.999	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.001	0.999	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.001	0.999	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.999	0.001
H92.1 Otorrhoea	0.000	0.999	0.001
K55.8 Other vascular disorders of intestine	0.001	0.999	0.000
M66.1 Rupture of synovium	0.001	0.999	0.000
Q96.9 Turner's syndrome, unspecified	0.001	0.999	0.000
Q96 Turner's syndrome	0.001	0.999	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.999	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.001	0.999	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.001	0.999	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.001	0.999	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.001	0.999	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.001	0.999	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.001	0.999	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.001	0.999	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.001	0.999	0.000
C83.6 Undifferentiated (diffuse)	0.001	0.999	0.000
C83.5 Lymphoblastic (diffuse)	0.001	0.999	0.000
C83.4 Immunoblastic (diffuse)	0.001	0.999	0.000
C83.2 Mixed small and large cell (diffuse)	0.001	0.999	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.001	0.999	0.000
L29.9 Pruritus, unspecified	0.000	0.999	0.001
Q35-Q37 Cleft lip and cleft palate	0.001	0.999	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.999	0.001
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.001	0.999	0.000
G97.8 Other postprocedural disorders of nervous system	0.001	0.999	0.000
H18.4 Corneal degeneration	0.001	0.999	0.000
Q10.0 Congenital ptosis	0.001	0.999	0.000
Q14.1 Congenital malformation of retina	0.001	0.999	0.000
Q61.5 Medullary cystic kidney	0.000	0.999	0.001
R25.1 Tremor, unspecified	0.001	0.999	0.000
S27.1 Traumatic haemothorax	0.000	0.999	0.001
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.999	0.001
Q34 Other congenital malformations of respiratory system	0.001	0.999	0.000
Q33 Congenital malformations of lung	0.001	0.999	0.000
Q32 Congenital malformations of trachea and bronchus	0.001	0.999	0.000
Q31 Congenital malformations of larynx	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations