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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113542870
log Bayes Factor = 14.9563
Chromosome 2   position 115,489,878  (GRCh37) Explore rs113542870 on Ensembl!
Variant rs113542870 is part of Cluster X0204

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter II Neoplasms
0.996 0.004 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
S02 Fracture of skull and facial bones
0.992 0.008 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
I20 Angina pectoris
0.987 0.013 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.978 0.022 0.000
N30-N39 Other diseases of urinary system
0.977 0.023 0.000
Chapter V Mental and behavioural disorders
0.977 0.023 0.000
I30-I52 Other forms of heart disease
0.968 0.032 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.966 0.034 0.000
A00-A09 Intestinal infectious diseases
0.964 0.036 0.000
N30 Cystitis
0.963 0.037 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.960 0.040 0.000
N20-N23 Urolithiasis
0.960 0.040 0.000
N30.9 Cystitis, unspecified
0.957 0.043 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.956 0.044 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.955 0.045 0.000
A04 Other bacterial intestinal infections
0.950 0.050 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.946 0.054 0.000
C78.7 Secondary malignant neoplasm of liver
0.944 0.056 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.943 0.057 0.000
I25.2 Old myocardial infarction
0.940 0.060 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.936 0.064 0.000
N20 Calculus of kidney and ureter
0.936 0.064 0.000
I50 Heart failure
0.936 0.064 0.000
I20.9 Angina pectoris, unspecified
0.934 0.066 0.000
S80-S89 Injuries to the knee and lower leg
0.933 0.067 0.000
B95-B98 Bacterial, viral and other infectious agents
0.924 0.076 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.918 0.082 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.917 0.083 0.000
I60-I69 Cerebrovascular diseases
0.917 0.083 0.000
I22 Subsequent myocardial infarction
0.914 0.086 0.000
S06 Intracranial injury
0.914 0.086 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.908 0.092 0.000
I25.1 Atherosclerotic heart disease
0.906 0.094 0.000
C15-C26 Malignant neoplasms of digestive organs
0.904 0.096 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.904 0.096 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.904 0.096 0.000
S02.1 Fracture of base of skull
0.902 0.098 0.000
C60-C63 Malignant neoplasms of male genital organs
0.902 0.098 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.901 0.099 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.900 0.100 0.000
S02.2 Fracture of nasal bones
0.900 0.100 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.895 0.105 0.000
A30-A49 Other bacterial diseases
0.894 0.106 0.000
F10.2 Dependence syndrome
0.890 0.110 0.000
B35-B49 Mycoses
0.887 0.113 0.000
Chapter XX External causes of morbidity and mortality
0.883 0.117 0.000
I45 Other conduction disorders
0.879 0.121 0.000
I50.0 Congestive heart failure
0.877 0.123 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.877 0.123 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.874 0.126 0.000
N60-N64 Disorders of breast
0.874 0.126 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.873 0.127 0.000
S05 Injury of eye and orbit
0.872 0.128 0.000
S70-S79 Injuries to the hip and thigh
0.870 0.130 0.000
I20.0 Unstable angina
0.868 0.132 0.000
T39.1 4-Aminophenol derivatives
0.866 0.134 0.000
S01 Open wound of head
0.866 0.134 0.000
R42 Dizziness and giddiness
0.864 0.136 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.864 0.136 0.000
I67 Other cerebrovascular diseases
0.863 0.137 0.000
N00-N08 Glomerular diseases
0.862 0.138 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.862 0.138 0.000
I24 Other acute ischaemic heart diseases
0.858 0.142 0.000
O47 False labour
0.858 0.142 0.000
I25.5 Ischaemic cardiomyopathy
0.857 0.142 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.856 0.144 0.000
I20.8 Other forms of angina pectoris
0.856 0.144 0.000
I51 Complications and ill-defined descriptions of heart disease
0.855 0.145 0.000
N20.1 Calculus of ureter
0.855 0.145 0.000
S82 Fracture of lower leg, including ankle
0.854 0.146 0.000
N39 Other disorders of urinary system
0.853 0.147 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.848 0.152 0.000
C18 Malignant neoplasm of colon
0.847 0.153 0.000
S00 Superficial injury of head
0.841 0.159 0.000
N39.0 Urinary tract infection, site not specified
0.840 0.160 0.000
S02.10 Fracture of base of skull (closed)
0.838 0.162 0.000
C61 Malignant neoplasm of prostate
0.837 0.163 0.000
S09 Other and unspecified injuries of head
0.837 0.163 0.000
S02.20 Fracture of nasal bones (closed)
0.835 0.165 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.834 0.166 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.833 0.167 0.000
S02.4 Fracture of malar and maxillary bones
0.833 0.167 0.000
T36 Poisoning by systemic antibiotics
0.831 0.169 0.000
S20-S29 Injuries to the thorax
0.831 0.169 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.830 0.170 0.000
F10.3 Withdrawal state
0.827 0.173 0.000
N20.2 Calculus of kidney with calculus of ureter
0.826 0.174 0.000
R44.1 Visual hallucinations
0.823 0.177 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.822 0.178 0.000
A04.5 Campylobacter enteritis
0.821 0.179 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.820 0.180 0.000
Q60-Q64 Congenital malformations of the urinary system
0.819 0.181 0.000
C79 Secondary malignant neoplasm of other sites
0.819 0.181 0.000
I21 Acute myocardial infarction
0.815 0.185 0.000
I67.8 Other specified cerebrovascular diseases
0.815 0.185 0.000
T66-T78 Other and unspecified effects of external causes
0.814 0.186 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.814 0.186 0.000
N36 Other disorders of urethra
0.812 0.188 0.000
S02.0 Fracture of vault of skull
0.808 0.192 0.000
R27 Other lack of coordination
0.807 0.193 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.806 0.194 0.000
I61 Intracerebral haemorrhage
0.805 0.195 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.803 0.197 0.000
R45 Symptoms and signs involving emotional state
0.803 0.197 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.802 0.198 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.802 0.198 0.000
I34 Nonrheumatic mitral valve disorders
0.801 0.199 0.000
A41 Other septicaemia
0.800 0.200 0.000
I05-I09 Chronic rheumatic heart diseases
0.799 0.201 0.000
R44.0 Auditory hallucinations
0.798 0.202 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.795 0.205 0.000
S10-S19 Injuries to the neck
0.794 0.206 0.000
S82.8 Fractures of other parts of lower leg
0.793 0.207 0.000
C73 Malignant neoplasm of thyroid gland
0.791 0.209 0.000
F60-F69 Disorders of adult personality and behaviour
0.790 0.210 0.000
A80-A89 Viral infections of the central nervous system
0.789 0.211 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.789 0.211 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.789 0.211 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.788 0.212 0.000
I50.1 Left ventricular failure
0.785 0.215 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.785 0.215 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.783 0.217 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.782 0.218 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.782 0.218 0.000
R41.0 Disorientation, unspecified
0.781 0.219 0.000
N25-N29 Other disorders of kidney and ureter
0.781 0.219 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.780 0.220 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.780 0.220 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.780 0.220 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.780 0.220 0.000
N60 Benign mammary dysplasia
0.779 0.221 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.779 0.221 0.000
T51 Toxic effect of alcohol
0.778 0.222 0.000
I69 Sequelae of cerebrovascular disease
0.778 0.222 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.775 0.225 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.774 0.226 0.000
S32 Fracture of lumbar spine and pelvis
0.774 0.226 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.774 0.226 0.000
I38 Endocarditis, valve unspecified
0.774 0.226 0.000
N10-N16 Renal tubulo-interstitial diseases
0.773 0.227 0.000
B37 Candidiasis
0.773 0.227 0.000
O36 Maternal care for other known or suspected foetal problems
0.773 0.227 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.769 0.231 0.000
N20.0 Calculus of kidney
0.767 0.233 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.762 0.238 0.000
F10.4 Withdrawal state with delirium
0.762 0.238 0.000
T39.0 Salicylates
0.762 0.238 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.760 0.240 0.000
R27.0 Ataxia, unspecified
0.760 0.240 0.000
S72 Fracture of femur
0.758 0.242 0.000
S05.1 Contusion of eyeball and orbital tissues
0.758 0.242 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.757 0.243 0.000
I36 Nonrheumatic tricuspid valve disorders
0.756 0.244 0.000
S89 Other and unspecified injuries of lower leg
0.755 0.245 0.000
S02.6 Fracture of mandible
0.753 0.247 0.000
S06.5 Traumatic subdural haemorrhage
0.753 0.247 0.000
I50.9 Heart failure, unspecified
0.753 0.247 0.000
S50-S59 Injuries to the elbow and forearm
0.751 0.249 0.000
Q61 Cystic kidney disease
0.751 0.249 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.750 0.250 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.749 0.251 0.000
I45.6 Preexcitation syndrome
0.748 0.252 0.000
I20.1 Angina pectoris with documented spasm
0.748 0.252 0.000
C18.0 Caecum
0.747 0.253 0.000
I51.9 Heart disease, unspecified
0.746 0.254 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.745 0.255 0.000
F99-F99 Unspecified mental disorder
0.745 0.255 0.000
S02.5 Fracture of tooth
0.743 0.257 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.743 0.257 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.741 0.258 0.000
I30 Acute pericarditis
0.741 0.259 0.000
W20-W49 Exposure to inanimate mechanical forces
0.740 0.260 0.000
S90-S99 Injuries to the ankle and foot
0.740 0.260 0.000
O41 Other disorders of amniotic fluid and membranes
0.740 0.260 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.739 0.261 0.000
R40 Somnolence, stupor and coma
0.738 0.261 0.000
B25-B34 Other viral diseases
0.736 0.264 0.000
S82.6 Fracture of lateral malleolus
0.735 0.265 0.000
S06.2 Diffuse brain injury
0.734 0.265 0.000
S02.3 Fracture of orbital floor
0.733 0.267 0.000
C64-C68 Malignant neoplasms of urinary tract
0.732 0.268 0.000
C51-C58 Malignant neoplasms of female genital organs
0.732 0.268 0.000
S01.8 Open wound of other parts of head
0.731 0.269 0.000
N20.9 Urinary calculus, unspecified
0.729 0.271 0.000
B37.8 Candidiasis of other sites
0.729 0.271 0.000
C15 Malignant neoplasm of oesophagus
0.729 0.271 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.727 0.273 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.724 0.275 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.724 0.276 0.000
T79-T79 Certain early complications of trauma
0.722 0.278 0.000
S09.9 Unspecified injury of head
0.721 0.279 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.720 0.280 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.719 0.281 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.719 0.281 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.718 0.282 0.000
S06.3 Focal brain injury
0.718 0.282 0.000
I45.9 Conduction disorder, unspecified
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.717 0.283 0.000
T36.0 Penicillins
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.716 0.284 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.286 0.000
D00-D09 In situ neoplasms
0.713 0.287 0.000
S00.8 Superficial injury of other parts of head
0.712 0.288 0.000
S02.8 Fractures of other skull and facial bones
0.711 0.289 0.000
S02.7 Multiple fractures involving skull and facial bones
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.710 0.290 0.000
F05.9 Delirium, unspecified
0.710 0.290 0.000
A46 Erysipelas
0.710 0.290 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.710 0.290 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.709 0.291 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.708 0.292 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.705 0.295 0.000
N39.9 Disorder of urinary system, unspecified
0.704 0.296 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.704 0.296 0.000
I67.1 Cerebral aneurysm, nonruptured
0.704 0.296 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.703 0.297 0.000
A40 Streptococcal septicaemia
0.702 0.298 0.000
N37 Urethral disorders in diseases classified elsewhere
0.701 0.299 0.000
N34 Urethritis and urethral syndrome
0.701 0.299 0.000
N33 Bladder disorders in diseases classified elsewhere
0.701 0.299 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.700 0.300 0.000
F70-F79 Mental retardation
0.700 0.300 0.000
C78.0 Secondary malignant neoplasm of lung
0.700 0.300 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.700 0.300 0.000
N23 Unspecified renal colic
0.699 0.301 0.000
O47.0 False labour before 37 completed weeks of gestation
0.699 0.301 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.699 0.301 0.000
W00-W19 Falls
0.698 0.302 0.000
T51.0 Ethanol
0.695 0.305 0.000
I52 Other heart disorders in diseases classified elsewhere
0.694 0.306 0.000
I48 Atrial fibrillation and flutter
0.694 0.306 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.694 0.306 0.000
I41 Myocarditis in diseases classified elsewhere
0.694 0.306 0.000
I40 Acute myocarditis
0.694 0.306 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.694 0.306 0.000
I37 Pulmonary valve disorders
0.694 0.306 0.000
I32 Pericarditis in diseases classified elsewhere
0.694 0.306 0.000
I24.8 Other forms of acute ischaemic heart disease
0.694 0.306 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.693 0.306 0.000
C18.7 Sigmoid colon
0.693 0.307 0.000
O46.9 Antepartum haemorrhage, unspecified
0.693 0.307 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.693 0.307 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.693 0.307 0.000
S06.8 Other intracranial injuries
0.692 0.308 0.000
S82.4 Fracture of fibula alone
0.691 0.308 0.000
A07 Other protozoal intestinal diseases
0.691 0.309 0.000
A06 Amoebiasis
0.691 0.309 0.000
A05 Other bacterial foodborne intoxications
0.691 0.309 0.000
A03 Shigellosis
0.691 0.309 0.000
A02 Other Salmonella infections
0.691 0.309 0.000
A01 Typhoid and paratyphoid fevers
0.691 0.309 0.000
A00 Cholera
0.691 0.309 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.691 0.309 0.000
N30.4 Irradiation cystitis
0.690 0.310 0.000
I42 Cardiomyopathy
0.690 0.310 0.000
R41.3 Other amnesia
0.690 0.310 0.000
S00.7 Multiple superficial injuries of head
0.690 0.310 0.000
I51.4 Myocarditis, unspecified
0.690 0.310 0.000
N36.9 Urethral disorder, unspecified
0.689 0.311 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.688 0.312 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.688 0.312 0.000
N30.0 Acute cystitis
0.688 0.312 0.000
C18.9 Colon, unspecified
0.688 0.312 0.000
I33 Acute and subacute endocarditis
0.688 0.312 0.000
R25 Abnormal involuntary movements
0.686 0.314 0.000
C78.2 Secondary malignant neoplasm of pleura
0.686 0.314 0.000
R46 Symptoms and signs involving appearance and behaviour
0.686 0.314 0.000
R43 Disturbances of smell and taste
0.686 0.314 0.000
B49 Unspecified mycosis
0.685 0.314 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.685 0.315 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.685 0.315 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.685 0.315 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.685 0.315 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.685 0.315 0.000
I51.8 Other ill-defined heart diseases
0.684 0.316 0.000
I34.1 Mitral (valve) prolapse
0.683 0.317 0.000
Chapter XXII Codes for special purposes
0.681 0.318 0.000
A04.9 Bacterial intestinal infection, unspecified
0.681 0.319 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.681 0.319 0.000
A04.4 Other intestinal Escherichia coli infections
0.681 0.319 0.000
A04.3 Enterohaemorrhagic Escherichia coli infection
0.681 0.319 0.000
A04.2 Enteroinvasive Escherichia coli infection
0.681 0.319 0.000
A04.1 Enterotoxigenic Escherichia coli infection
0.681 0.319 0.000
A04.0 Enteropathogenic Escherichia coli infection
0.681 0.319 0.000
B44 Aspergillosis
0.681 0.319 0.000
I45.2 Bifascicular block
0.680 0.319 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.680 0.320 0.000
O44 Placenta praevia
0.680 0.320 0.000
O30 Multiple gestation
0.679 0.320 0.000
O40 Polyhydramnios
0.679 0.321 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.678 0.322 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.678 0.322 0.000
T39.4 Antirheumatics, not elsewhere classified
0.678 0.322 0.000
T39.2 Pyrazolone derivatives
0.678 0.322 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.678 0.322 0.000
S80 Superficial injury of lower leg
0.678 0.322 0.000
C18.4 Transverse colon
0.677 0.323 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.676 0.324 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.676 0.324 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.676 0.324 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.676 0.324 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.676 0.324 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.676 0.324 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.676 0.324 0.000
F11 Mental and behavioural disorders due to use of opioids
0.676 0.324 0.000
S02.00 Fracture of vault of skull (closed)
0.676 0.324 0.000
N30.1 Interstitial cystitis (chronic)
0.674 0.326 0.000
S05.8 Other injuries of eye and orbit
0.674 0.326 0.000
C21 Malignant neoplasm of anus and anal canal
0.673 0.327 0.000
S01.5 Open wound of lip and oral cavity
0.672 0.328 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.672 0.328 0.000
N30.2 Other chronic cystitis
0.672 0.328 0.000
S79 Other and unspecified injuries of hip and thigh
0.671 0.328 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.671 0.329 0.000
S01.9 Open wound of head, part unspecified
0.670 0.330 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.670 0.330 0.000
S88 Traumatic amputation of lower leg
0.669 0.331 0.000
S87 Crushing injury of lower leg
0.669 0.331 0.000
S86 Injury of muscle and tendon at lower leg level
0.669 0.331 0.000
S85 Injury of blood vessels at lower leg level
0.669 0.331 0.000
S84 Injury of nerves at lower leg level
0.669 0.331 0.000
Q80-Q89 Other congenital malformations
0.668 0.332 0.000
I47 Paroxysmal tachycardia
0.668 0.332 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.667 0.333 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.666 0.334 0.000
Q61.3 Polycystic kidney, unspecified
0.666 0.334 0.000
A08 Viral and other specified intestinal infections
0.665 0.334 0.000
N36.0 Urethral fistula
0.664 0.336 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.664 0.336 0.000
N61 Inflammatory disorders of breast
0.663 0.337 0.000
N72 Inflammatory disease of cervix uteri
0.662 0.338 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.662 0.338 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.662 0.338 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.661 0.339 0.000
N64 Other disorders of breast
0.660 0.340 0.000
F30-F39 Mood [affective] disorders
0.659 0.341 0.000
F10.9 Unspecified mental and behavioural disorder
0.658 0.341 0.000
F10.8 Other mental and behavioural disorders
0.658 0.341 0.000
F10.7 Residual and late-onset psychotic disorder
0.658 0.341 0.000
F10.6 Amnesic syndrome
0.658 0.341 0.000
F10.5 Psychotic disorder
0.658 0.341 0.000
N21 Calculus of lower urinary tract
0.658 0.342 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.657 0.342 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.657 0.342 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.657 0.342 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.657 0.343 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.657 0.343 0.000
C80 Malignant neoplasm without specification of site
0.656 0.343 0.000
R80 Isolated proteinuria
0.656 0.343 0.000
Q50-Q56 Congenital malformations of genital organs
0.656 0.344 0.000
F60 Specific personality disorders
0.656 0.344 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.655 0.345 0.000
I22.8 Subsequent myocardial infarction of other sites
0.655 0.345 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.655 0.345 0.000
S06.9 Intracranial injury, unspecified
0.655 0.345 0.000
S06.7 Intracranial injury with prolonged coma
0.655 0.345 0.000
S06.4 Epidural haemorrhage
0.655 0.345 0.000
S06.1 Traumatic cerebral oedema
0.655 0.345 0.000
S06.0 Concussion
0.655 0.345 0.000
B15-B19 Viral hepatitis
0.654 0.346 0.000
C45 Mesothelioma
0.654 0.346 0.000
S01.2 Open wound of nose
0.653 0.347 0.000
X60-X84 Intentional self-harm
0.653 0.347 0.000
S72.1 Pertrochanteric fracture
0.651 0.348 0.000
V20-V29 Motorcycle rider injured in transport accident
0.651 0.349 0.000
O85-O92 Complications predominantly related to the puerperium
0.651 0.349 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.651 0.349 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.650 0.350 0.000
N60.3 Fibrosclerosis of breast
0.650 0.350 0.000
S82.60 Fracture of lateral malleolus (closed)
0.649 0.351 0.000
F01 Vascular dementia
0.649 0.351 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.649 0.351 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.648 0.351 0.000
C17 Malignant neoplasm of small intestine
0.648 0.351 0.000
C23 Malignant neoplasm of gallbladder
0.648 0.351 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.648 0.352 0.000
S37 Injury of urinary and pelvic organs
0.648 0.352 0.000
S36 Injury of intra-abdominal organs
0.648 0.352 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.648 0.352 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.648 0.352 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.648 0.352 0.000
S31 Open wound of abdomen, lower back and pelvis
0.648 0.352 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.648 0.352 0.000
R44.2 Other hallucinations
0.648 0.352 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.648 0.352 0.000
R74 Abnormal serum enzyme levels
0.648 0.352 0.000
O47.9 False labour, unspecified
0.647 0.353 0.000
S02.11 Fracture of base of skull (open)
0.647 0.353 0.000
C81 Hodgkin's disease
0.647 0.353 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.646 0.353 0.000
C60 Malignant neoplasm of penis
0.646 0.353 0.000
O45 Premature separation of placenta [abruptio placentae]
0.646 0.354 0.000
O43 Placental disorders
0.646 0.354 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.646 0.354 0.000
O33 Maternal care for known or suspected disproportion
0.646 0.354 0.000
O31 Complications specific to multiple gestation
0.646 0.354 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.646 0.354 0.000
Q35-Q37 Cleft lip and cleft palate
0.646 0.354 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.646 0.354 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.646 0.354 0.000
A41.9 Septicaemia, unspecified
0.646 0.354 0.000
S02.21 Fracture of nasal bones (open)
0.645 0.354 0.000
N62 Hypertrophy of breast
0.645 0.354 0.000
N02 Recurrent and persistent haematuria
0.645 0.355 0.000
S01.1 Open wound of eyelid and periocular area
0.645 0.355 0.000
R45.1 Restlessness and agitation
0.645 0.355 0.000
C18.6 Descending colon
0.645 0.355 0.000
R45.8 Other symptoms and signs involving emotional state
0.644 0.356 0.000
O00-O08 Pregnancy with abortive outcome
0.644 0.356 0.000
N13 Obstructive and reflux uropathy
0.643 0.357 0.000
S27 Injury of other and unspecified intrathoracic organs
0.643 0.357 0.000
T78 Adverse effects, not elsewhere classified
0.643 0.357 0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.643 0.357 0.000
A41.8 Other specified septicaemia
0.643 0.357 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.643 0.357 0.000
O36.5 Maternal care for poor foetal growth
0.642 0.358 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.642 0.358 0.000
A48 Other bacterial diseases, not elsewhere classified
0.641 0.359 0.000
A44 Bartonellosis
0.641 0.359 0.000
A43 Nocardiosis
0.641 0.359 0.000
A42 Actinomycosis
0.641 0.359 0.000
A39 Meningococcal infection
0.641 0.359 0.000
A37 Whooping cough
0.641 0.359 0.000
A36 Diphtheria
0.641 0.359 0.000
A32 Listeriosis
0.641 0.359 0.000
A31 Infection due to other mycobacteria
0.641 0.359 0.000
A30 Leprosy [Hansen's disease]
0.641 0.359 0.000
A38 Scarlet fever
0.641 0.359 0.000
A35 Other tetanus
0.641 0.359 0.000
A34 Obstetrical tetanus
0.641 0.359 0.000
A33 Tetanus neonatorum
0.641 0.359 0.000
T63 Toxic effect of contact with venomous animals
0.640 0.360 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.640 0.360 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.640 0.360 0.000
A87 Viral meningitis
0.639 0.360 0.000
I45.5 Other specified heart block
0.639 0.361 0.000
N03 Chronic nephritic syndrome
0.639 0.361 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.638 0.362 0.000
I62 Other nontraumatic intracranial haemorrhage
0.638 0.362 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.637 0.363 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.637 0.363 0.000
B48 Other mycoses, not elsewhere classified
0.636 0.364 0.000
B47 Mycetoma
0.636 0.364 0.000
B46 Zygomycosis
0.636 0.364 0.000
B45 Cryptococcosis
0.636 0.364 0.000
B43 Chromomycosis and phaeomycotic abscess
0.636 0.364 0.000
B42 Sporotrichosis
0.636 0.364 0.000
B41 Paracoccidioidomycosis
0.636 0.364 0.000
B40 Blastomycosis
0.636 0.364 0.000
B39 Histoplasmosis
0.636 0.364 0.000
B38 Coccidioidomycosis
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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