TreeWAS – Variant ID: rs11581859

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C71.9 Brain, unspecified	0.000	0.984	0.016
C71.1 Frontal lobe	0.000	0.984	0.016
C71 Malignant neoplasm of brain	0.000	0.984	0.016
C71.4 Occipital lobe	0.000	0.986	0.013
C71.0 Cerebrum, except lobes and ventricles	0.000	0.987	0.013
C71.2 Temporal lobe	0.000	0.987	0.013
C71.8 Overlapping lesion of brain	0.000	0.988	0.012
C71.6 Cerebellum	0.000	0.988	0.011
C71.5 Cerebral ventricle	0.000	0.988	0.011
C71.7 Brain stem	0.000	0.989	0.011
Z72.1 Alcohol use	0.000	0.990	0.010
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.990	0.010
C71.3 Parietal lobe	0.000	0.992	0.008
I69.3 Sequelae of cerebral infarction	0.007	0.993	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.007	0.993	0.000
I69 Sequelae of cerebrovascular disease	0.007	0.993	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.007	0.993	0.000
H33.3 Retinal breaks without detachment	0.007	0.993	0.000
T40.2 Other opioids	0.006	0.994	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.006	0.994	0.000
N36.0 Urethral fistula	0.000	0.994	0.006
X62.9 Unspecified place	0.006	0.994	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.994	0.006
L81.9 Disorder of pigmentation, unspecified	0.005	0.995	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.000	0.995	0.005
Z72 Problems related to lifestyle	0.000	0.995	0.005
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.995	0.005
C70 Malignant neoplasm of meninges	0.000	0.995	0.004
H02.9 Disorder of eyelid, unspecified	0.000	0.995	0.005
R61.9 Hyperhidrosis, unspecified	0.004	0.996	0.000
Z49.0 Preparatory care for dialysis	0.000	0.996	0.004
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.004	0.996	0.000
Z72.0 Tobacco use	0.000	0.996	0.004
E55.9 Vitamin D deficiency, unspecified	0.004	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
K81.1 Chronic cholecystitis	0.000	0.996	0.004
C72.0 Spinal cord	0.000	0.996	0.004
C70.0 Cerebral meninges	0.000	0.996	0.004
Z72.9 Problem related to lifestyle, unspecified	0.000	0.996	0.003
Z72.6 Gambling and betting	0.000	0.996	0.003
Z72.5 High-risk sexual behaviour	0.000	0.996	0.003
Z72.3 Lack of physical exercise	0.000	0.996	0.003
R22.2 Localised swelling, mass and lump, trunk	0.004	0.996	0.000
C72.9 Central nervous system, unspecified	0.000	0.996	0.003
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.996	0.003
C72.5 Other and unspecified cranial nerves	0.000	0.996	0.003
C72.4 Acoustic nerve	0.000	0.996	0.003
C72.3 Optic nerve	0.000	0.996	0.003
C72.2 Olfactory nerve	0.000	0.996	0.003
C72.1 Cauda equina	0.000	0.996	0.003
Q23.1 Congenital insufficiency of aortic valve	0.004	0.996	0.000
C70.9 Meninges, unspecified	0.000	0.996	0.003
C70.1 Spinal meninges	0.000	0.996	0.003
Z72.2 Drug use	0.000	0.996	0.003
Z88.2 Personal history of allergy to sulphonamides	0.004	0.996	0.000
B25.9 Cytomegaloviral disease, unspecified	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.997	0.003
Z72.8 Other problems related to lifestyle	0.000	0.997	0.003
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.003	0.997	0.000
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.003	0.997	0.000
Z72.4 Inappropriate diet and eating habits	0.000	0.997	0.003
M89.8 Other specified disorders of bone	0.003	0.997	0.000
C17.9 Small intestine, unspecified	0.000	0.997	0.003
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
M89 Other disorders of bone	0.003	0.997	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.997	0.003
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.997	0.000
M22.4 Chondromalacia patellae	0.000	0.997	0.003
H33.1 Retinoschisis and retinal cysts	0.003	0.997	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.003	0.997	0.000
Z94.8 Other transplanted organ and tissue status	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.997	0.002
C69.5 Lachrymal gland and duct	0.000	0.997	0.002
C69.4 Ciliary body	0.000	0.997	0.002
C69.2 Retina	0.000	0.997	0.002
C69.1 Cornea	0.000	0.997	0.002
C69.0 Conjunctiva	0.000	0.997	0.002
F33.9 Recurrent depressive disorder, unspecified	0.000	0.997	0.003
M89.3 Hypertrophy of bone	0.003	0.997	0.000
M89.5 Osteolysis	0.003	0.997	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.003	0.997	0.000
C69.6 Orbit	0.000	0.997	0.002
X62.0 Home	0.002	0.997	0.000
X62.8 Other specified place	0.002	0.997	0.000
X62.7 Farm	0.002	0.997	0.000
X62.6 Industrial and construction area	0.002	0.997	0.000
X62.5 Trade and service area	0.002	0.997	0.000
X62.4 Street and highway	0.002	0.997	0.000
X62.3 Sports and athletics area	0.002	0.997	0.000
X62.2 School, other institution and public administrative area	0.002	0.997	0.000
X62.1 Residential institution	0.002	0.997	0.000
N36 Other disorders of urethra	0.000	0.997	0.003
K55.0 Acute vascular disorders of intestine	0.003	0.997	0.000
H33 Retinal detachments and breaks	0.003	0.997	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
B25 Cytomegaloviral disease	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.002
B25.8 Other cytomegaloviral diseases	0.002	0.998	0.000
C69.3 Choroid	0.000	0.998	0.002
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
E55 Vitamin D deficiency	0.002	0.998	0.000
K50.9 Crohn's disease, unspecified	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.002	0.998	0.000
E87.2 Acidosis	0.000	0.998	0.002
H33.4 Traction detachment of retina	0.002	0.998	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.998	0.002
M89.37 Hypertrophy of bone (Ankle and foot)	0.002	0.998	0.000
C69.9 Eye, unspecified	0.000	0.998	0.002
H43.3 Other vitreous opacities	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
L81 Other disorders of pigmentation	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
R85.7 Abnormal histological findings	0.002	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
N36.9 Urethral disorder, unspecified	0.000	0.998	0.002
R61 Hyperhidrosis	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
N36.8 Other specified disorders of urethra	0.000	0.998	0.002
B25.2 Cytomegaloviral pancreatitis	0.002	0.998	0.000
B25.1 Cytomegaloviral hepatitis	0.002	0.998	0.000
B25.0 Cytomegaloviral pneumonitis	0.002	0.998	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.002	0.998	0.000
J92 Pleural plaque	0.000	0.998	0.002
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.002	0.998	0.000
E55.0 Rickets, active	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
L81.8 Other specified disorders of pigmentation	0.002	0.998	0.000
R22.1 Localised swelling, mass and lump, neck	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
C17.2 Ileum	0.000	0.998	0.002
W18.3 Sports and athletics area	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
C17 Malignant neoplasm of small intestine	0.000	0.998	0.002
N60.4 Mammary duct ectasia	0.000	0.998	0.002
R61.0 Localised hyperhidrosis	0.002	0.998	0.000
N36.1 Urethral diverticulum	0.000	0.998	0.002
Y65.8 Other specified misadventures during surgical and medical care	0.002	0.998	0.000
H35.9 Retinal disorder, unspecified	0.000	0.998	0.002
L81.7 Pigmented purpuric dermatosis	0.002	0.998	0.000
L81.6 Other disorders of diminished melanin formation	0.002	0.998	0.000
L81.5 Leukoderma, not elsewhere classified	0.002	0.998	0.000
L81.3 Cafe au lait spots	0.002	0.998	0.000
L81.1 Chloasma	0.002	0.998	0.000
L81.0 Postinflammatory hyperpigmentation	0.002	0.998	0.000
N41.1 Chronic prostatitis	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.998	0.002
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
N36.2 Urethral caruncle	0.000	0.998	0.002
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
R61.1 Generalised hyperhidrosis	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
H33.5 Other retinal detachments	0.002	0.998	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.002	0.998	0.000
R85.5 Abnormal microbiological findings	0.002	0.998	0.000
T42.1 Iminostilbenes	0.000	0.998	0.002
Z49 Care involving dialysis	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
C17.0 Duodenum	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
C67.5 Bladder neck	0.000	0.998	0.002
K59.3 Megacolon, not elsewhere classified	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
Z49.2 Other dialysis	0.000	0.998	0.002
C91.1 Chronic lymphocytic leukaemia	0.000	0.998	0.002
W18.5 Trade and service area	0.000	0.998	0.002
Z12.5 Special screening examination for neoplasm of prostate	0.002	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
L81.2 Freckles	0.002	0.998	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.998	0.002
T42.0 Hydantoin derivatives	0.000	0.998	0.001
Y45.1 Salicylates	0.002	0.998	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
N50.8 Other specified disorders of male genital organs	0.000	0.998	0.002
M89.07 Algoneurodystrophy (Ankle and foot)	0.001	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
C17.8 Overlapping lesion of small intestine	0.000	0.998	0.001
C17.3 Meckel's diverticulum	0.000	0.998	0.001
O47.9 False labour, unspecified	0.000	0.998	0.002
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.001
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.001	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.998	0.000
C67.0 Trigone of bladder	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.001	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.002	0.998	0.000
C67.2 Lateral wall of bladder	0.000	0.998	0.002
R85.8 Other abnormal findings	0.001	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.998	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.001	0.998	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.001	0.998	0.000
L81.4 Other melanin hyperpigmentation	0.001	0.998	0.000
C17.1 Jejunum	0.000	0.999	0.001
G58.9 Mononeuropathy, unspecified	0.000	0.999	0.001
N91.2 Amenorrhoea, unspecified	0.001	0.999	0.000
O00.1 Tubal pregnancy	0.001	0.999	0.000
Q18.1 Preauricular sinus and cyst	0.001	0.999	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.999	0.001
R22.4 Localised swelling, mass and lump, lower limb	0.001	0.999	0.000
H35.5 Hereditary retinal dystrophy	0.001	0.999	0.000
K50.1 Crohn's disease of large intestine	0.000	0.999	0.001
R85.9 Unspecified abnormal finding	0.001	0.999	0.000
R85.6 Abnormal cytological findings	0.001	0.999	0.000
R85.4 Abnormal immunological findings	0.001	0.999	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R85.1 Abnormal level of hormones	0.001	0.999	0.000
R85.0 Abnormal level of enzymes	0.001	0.999	0.000
M90 Osteopathies in diseases classified elsewhere	0.001	0.999	0.000
Q18 Other congenital malformations of face and neck	0.001	0.999	0.000
T40.5 Cocaine	0.001	0.999	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.001	0.999	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.999	0.000
Q43.7 Persistent cloaca	0.001	0.999	0.000
Q43.6 Congenital fistula of rectum and anus	0.001	0.999	0.000
Q43.5 Ectopic anus	0.001	0.999	0.000
Q43.4 Duplication of intestine	0.001	0.999	0.000
Q43.2 Other congenital functional disorders of colon	0.001	0.999	0.000
Q43.1 Hirschsprung's disease	0.001	0.999	0.000
C67.8 Overlapping lesion of bladder	0.000	0.999	0.001
O21.9 Vomiting of pregnancy, unspecified	0.000	0.999	0.001
Q43.8 Other specified congenital malformations of intestine	0.001	0.999	0.000
Y65.4 Failure to introduce or to remove other tube or instrument	0.001	0.999	0.000
C67 Malignant neoplasm of bladder	0.000	0.999	0.001
W18 Other fall on same level	0.000	0.999	0.001
C67.3 Anterior wall of bladder	0.000	0.999	0.001
C67.1 Dome of bladder	0.000	0.999	0.001
D46.7 Other myelodysplastic syndromes	0.001	0.999	0.000
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
G93.9 Disorder of brain, unspecified	0.001	0.999	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.001	0.999	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.001	0.999	0.000
T40.8 Lysergide [LSD]	0.001	0.999	0.000
T40.7 Cannabis (derivatives)	0.001	0.999	0.000
T40.3 Methadone	0.001	0.999	0.000
T40.1 Heroin	0.001	0.999	0.000
T40.0 Opium	0.001	0.999	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y84.8 Other medical procedures	0.001	0.999	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.001	0.999	0.000
N41 Inflammatory diseases of prostate	0.000	0.999	0.001
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
S14.3 Injury of brachial plexus	0.001	0.999	0.000
Y65 Other misadventures during surgical and medical care	0.001	0.999	0.000
L65.9 Nonscarring hair loss, unspecified	0.001	0.999	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.999	0.000
D86 Sarcoidosis	0.001	0.999	0.000
H33.2 Serous retinal detachment	0.001	0.999	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.000	0.999	0.001
I22.8 Subsequent myocardial infarction of other sites	0.000	0.999	0.001
M90.8 Osteopathy in other diseases classified elsewhere	0.001	0.999	0.000
M90.6 Osteitis deformans in neoplastic disease	0.001	0.999	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.001	0.999	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.001	0.999	0.000
M90.3 Osteonecrosis in caisson disease	0.001	0.999	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.001	0.999	0.000
M90.0 Tuberculosis of bone	0.001	0.999	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.001	0.999	0.000
Q18.8 Other specified congenital malformations of face and neck	0.001	0.999	0.000
Q18.7 Microcheilia	0.001	0.999	0.000
Q18.6 Macrocheilia	0.001	0.999	0.000
Q18.5 Microstomia	0.001	0.999	0.000
Q18.4 Macrostomia	0.001	0.999	0.000
Q18.3 Webbing of neck	0.001	0.999	0.000
Q18.2 Other branchial cleft malformations	0.001	0.999	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.001	0.999	0.000
T18.1 Foreign body in oesophagus	0.001	0.999	0.000
B35.3 Tinea pedis	0.000	0.999	0.001
C79.9 Secondary malignant neoplasm, unspecified site	0.001	0.999	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.001	0.999	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y79.0 Diagnostic and monitoring devices	0.001	0.999	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.001	0.999	0.000
C67.7 Urachus	0.000	0.999	0.001
H59.8 Other postprocedural disorders of eye and adnexa	0.001	0.999	0.000
W18.9 Unspecified place	0.000	0.999	0.001
W18.8 Other specified place	0.000	0.999	0.001
W18.4 Street and highway	0.000	0.999	0.001
W18.2 School, other institution and public administrative area	0.000	0.999	0.001
W18.0 Home	0.000	0.999	0.001
W18.7 Farm	0.000	0.999	0.001
W18.6 Industrial and construction area	0.000	0.999	0.001
W18.1 Residential institution	0.000	0.999	0.001
X50.4 Street and highway	0.001	0.999	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.999	0.001
E10.4 With neurological complications	0.001	0.999	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.999	0.001
N41.3 Prostatocystitis	0.000	0.999	0.001
N41.2 Abscess of prostate	0.000	0.999	0.001
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.999	0.001
Q79.0 Congenital diaphragmatic hernia	0.001	0.999	0.000
C01 Malignant neoplasm of base of tongue	0.001	0.999	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.001	0.999	0.000
C25.9 Pancreas, unspecified	0.001	0.999	0.000
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
N41.0 Acute prostatitis	0.000	0.999	0.001
Y65.5 Performance of inappropriate operation	0.001	0.999	0.000
Y65.3 Endotracheal tube wrongly placed during anaesthetic procedure	0.001	0.999	0.000
Y65.2 Failure in suture or ligature during surgical operation	0.001	0.999	0.000
Y65.1 Wrong fluid used in infusion	0.001	0.999	0.000
Y65.0 Mismatched blood used in transfusion	0.001	0.999	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.999	0.001
M02.39 Reiter's disease (Site unspecified)	0.001	0.999	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
C10.9 Oropharynx, unspecified	0.001	0.999	0.000
I05.1 Rheumatic mitral insufficiency	0.001	0.999	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.001	0.999	0.000
N89.5 Stricture and atresia of vagina	0.000	0.999	0.001
Q43.3 Congenital malformations of intestinal fixation	0.001	0.999	0.000
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
S69.9 Unspecified injury of wrist and hand	0.000	0.999	0.001
Z12.8 Special screening examination for neoplasm of other sites	0.001	0.999	0.000
Z75.5 Holiday relief care	0.000	0.999	0.001
M25.94 Joint disorder, unspecified (Hand)	0.001	0.999	0.000
M90.09 Tuberculosis of bone (Site unspecified)	0.001	0.999	0.000
M90.08 Tuberculosis of bone (Other)	0.001	0.999	0.000
M90.07 Tuberculosis of bone (Ankle and foot)	0.001	0.999	0.000
M90.06 Tuberculosis of bone (Lower leg)	0.001	0.999	0.000
M90.05 Tuberculosis of bone (Pelvic region and thigh)	0.001	0.999	0.000
M90.04 Tuberculosis of bone (Hand)	0.001	0.999	0.000
M90.03 Tuberculosis of bone (Forearm)	0.001	0.999	0.000
M90.02 Tuberculosis of bone (Upper arm)	0.001	0.999	0.000
M90.01 Tuberculosis of bone (Shoulder region)	0.001	0.999	0.000
M90.00 Tuberculosis of bone (Multiple sites)	0.001	0.999	0.000
M90.29 Osteopathy in other infectious diseases classified elsewhere (Site unspecified)	0.001	0.999	0.000
M90.28 Osteopathy in other infectious diseases classified elsewhere (Other)	0.001	0.999	0.000
M90.27 Osteopathy in other infectious diseases classified elsewhere (Ankle and foot)	0.001	0.999	0.000
M90.26 Osteopathy in other infectious diseases classified elsewhere (Lower leg)	0.001	0.999	0.000
M90.25 Osteopathy in other infectious diseases classified elsewhere (Pelvic region and thigh)	0.001	0.999	0.000
M90.24 Osteopathy in other infectious diseases classified elsewhere (Hand)	0.001	0.999	0.000
M90.23 Osteopathy in other infectious diseases classified elsewhere (Forearm)	0.001	0.999	0.000
M90.22 Osteopathy in other infectious diseases classified elsewhere (Upper arm)	0.001	0.999	0.000
M90.21 Osteopathy in other infectious diseases classified elsewhere (Shoulder region)	0.001	0.999	0.000
M90.20 Osteopathy in other infectious diseases classified elsewhere (Multiple sites)	0.001	0.999	0.000
M90.39 Osteonecrosis in caisson disease (Site unspecified)	0.001	0.999	0.000
M90.38 Osteonecrosis in caisson disease (Other)	0.001	0.999	0.000
M90.37 Osteonecrosis in caisson disease (Ankle and foot)	0.001	0.999	0.000
M90.36 Osteonecrosis in caisson disease (Lower leg)	0.001	0.999	0.000
M90.35 Osteonecrosis in caisson disease (Pelvic region and thigh)	0.001	0.999	0.000
M90.34 Osteonecrosis in caisson disease (Hand)	0.001	0.999	0.000
M90.33 Osteonecrosis in caisson disease (Forearm)	0.001	0.999	0.000
M90.32 Osteonecrosis in caisson disease (Upper arm)	0.001	0.999	0.000
M90.31 Osteonecrosis in caisson disease (Shoulder region)	0.001	0.999	0.000
M90.30 Osteonecrosis in caisson disease (Multiple sites)	0.001	0.999	0.000
M90.49 Osteonecrosis due to haemoglobinopathy (Site unspecified)	0.001	0.999	0.000
M90.48 Osteonecrosis due to haemoglobinopathy (Other)	0.001	0.999	0.000
M90.47 Osteonecrosis due to haemoglobinopathy (Ankle and foot)	0.001	0.999	0.000
M90.46 Osteonecrosis due to haemoglobinopathy (Lower leg)	0.001	0.999	0.000
M90.45 Osteonecrosis due to haemoglobinopathy (Pelvic region and thigh)	0.001	0.999	0.000
M90.44 Osteonecrosis due to haemoglobinopathy (Hand)	0.001	0.999	0.000
M90.43 Osteonecrosis due to haemoglobinopathy (Forearm)	0.001	0.999	0.000
M90.42 Osteonecrosis due to haemoglobinopathy (Upper arm)	0.001	0.999	0.000
M90.41 Osteonecrosis due to haemoglobinopathy (Shoulder region)	0.001	0.999	0.000
M90.40 Osteonecrosis due to haemoglobinopathy (Multiple sites)	0.001	0.999	0.000
M90.59 Osteonecrosis in other diseases classified elsewhere (Site unspecified)	0.001	0.999	0.000
M90.58 Osteonecrosis in other diseases classified elsewhere (Other)	0.001	0.999	0.000
M90.57 Osteonecrosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.999	0.000
M90.56 Osteonecrosis in other diseases classified elsewhere (Lower leg)	0.001	0.999	0.000
M90.55 Osteonecrosis in other diseases classified elsewhere (Pelvic region and thigh)	0.001	0.999	0.000
M90.54 Osteonecrosis in other diseases classified elsewhere (Hand)	0.001	0.999	0.000
M90.53 Osteonecrosis in other diseases classified elsewhere (Forearm)	0.001	0.999	0.000
M90.52 Osteonecrosis in other diseases classified elsewhere (Upper arm)	0.001	0.999	0.000
M90.51 Osteonecrosis in other diseases classified elsewhere (Shoulder region)	0.001	0.999	0.000
M90.50 Osteonecrosis in other diseases classified elsewhere (Multiple sites)	0.001	0.999	0.000
M90.69 Osteitis deformans in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.68 Osteitis deformans in neoplastic disease (Other)	0.001	0.999	0.000
M90.67 Osteitis deformans in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.66 Osteitis deformans in neoplastic disease (Lower leg)	0.001	0.999	0.000
M90.65 Osteitis deformans in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
M90.64 Osteitis deformans in neoplastic disease (Hand)	0.001	0.999	0.000
M90.63 Osteitis deformans in neoplastic disease (Forearm)	0.001	0.999	0.000
M90.62 Osteitis deformans in neoplastic disease (Upper arm)	0.001	0.999	0.000
M90.61 Osteitis deformans in neoplastic disease (Shoulder region)	0.001	0.999	0.000
M90.60 Osteitis deformans in neoplastic disease (Multiple sites)	0.001	0.999	0.000
M90.89 Osteopathy in other diseases classified elsewhere (Site unspecified)	0.001	0.999	0.000
M90.88 Osteopathy in other diseases classified elsewhere (Other)	0.001	0.999	0.000
M90.87 Osteopathy in other diseases classified elsewhere (Ankle and foot)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations