TreeWAS – Variant ID: rs12124584

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
E10-E14 Diabetes mellitus	0.997	0.003
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.996	0.004
Chapter XX External causes of morbidity and mortality	0.996	0.004
R50-R69 General symptoms and signs	0.994	0.006
E70-E90 Metabolic disorders	0.992	0.008
E11 Non-insulin-dependent diabetes mellitus	0.987	0.013
R51 Headache	0.980	0.020
F30-F39 Mood [affective] disorders	0.980	0.020
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.980	0.020
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.974	0.026
E78.5 Hyperlipidaemia, unspecified	0.966	0.034
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.964	0.036
E86 Volume depletion	0.962	0.038
E11.9 Without complications	0.958	0.042
W00-W19 Falls	0.948	0.052
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.946	0.054
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.941	0.059
W20-W49 Exposure to inanimate mechanical forces	0.938	0.062
R53 Malaise and fatigue	0.937	0.063
F00-F09 Organic, including symptomatic, mental disorders	0.934	0.066
T66-T78 Other and unspecified effects of external causes	0.930	0.070
T20-T25 Burns and corrosions of external body surface, specified by site	0.930	0.070
F60-F69 Disorders of adult personality and behaviour	0.924	0.076
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.918	0.082
E11.5 With peripheral circulatory complications	0.915	0.085
S20-S29 Injuries to the thorax	0.914	0.086
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.914	0.086
F33 Recurrent depressive disorder	0.910	0.090
S10-S19 Injuries to the neck	0.909	0.091
F40-F48 Neurotic, stress-related and somatoform disorders	0.909	0.091
E11.3 With ophthalmic complications	0.906	0.094
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.905	0.095
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.904	0.095
F39 Unspecified mood [affective] disorder	0.893	0.107
T92 Sequelae of injuries of upper limb	0.893	0.107
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.889	0.111
R69 Unknown and unspecified causes of morbidity	0.887	0.113
E20-E35 Disorders of other endocrine glands	0.886	0.114
F31 Bipolar affective disorder	0.881	0.119
F05 Delirium, not induced by alcohol and other psychoactive substances	0.877	0.123
R80 Isolated proteinuria	0.874	0.126
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.873	0.127
R63 Symptoms and signs concerning food and fluid intake	0.873	0.127
E14 Unspecified diabetes mellitus	0.867	0.133
Y40 Systemic antibiotics	0.863	0.137
R68 Other general symptoms and signs	0.863	0.137
R81 Glycosuria	0.862	0.138
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.860	0.140
Chapter VII Diseases of the eye and adnexa	0.857	0.143
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.857	0.143
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.856	0.144
F60 Specific personality disorders	0.856	0.144
S27 Injury of other and unspecified intrathoracic organs	0.855	0.145
E10 Insulin-dependent diabetes mellitus	0.855	0.145
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.853	0.147
T92.1 Sequelae of fracture of arm	0.850	0.150
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.846	0.154
E88 Other metabolic disorders	0.846	0.154
W22 Striking against or struck by other objects	0.845	0.155
F33.9 Recurrent depressive disorder, unspecified	0.843	0.157
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.843	0.157
F43 Reaction to severe stress, and adjustment disorders	0.837	0.163
F05.9 Delirium, unspecified	0.837	0.163
S12 Fracture of neck	0.834	0.166
M86-M90 Other osteopathies	0.830	0.170
H30-H36 Disorders of choroid and retina	0.829	0.171
T14 Injury of unspecified body region	0.827	0.173
T68 Hypothermia	0.825	0.175
F25 Schizoaffective disorders	0.824	0.176
R26 Abnormalities of gait and mobility	0.823	0.177
H35 Other retinal disorders	0.819	0.181
T25 Burn and corrosion of ankle and foot	0.817	0.183
S27.0 Traumatic pneumothorax	0.817	0.183
W44 Foreign body entering into or through eye or natural orifice	0.816	0.184
Y49 Psychotropic drugs, not elsewhere classified	0.814	0.186
M70-M79 Other soft tissue disorders	0.810	0.190
W19 Unspecified fall	0.806	0.194
F20 Schizophrenia	0.805	0.195
F00 Dementia in Alzheimer's disease	0.805	0.195
F33.1 Recurrent depressive disorder, current episode moderate	0.805	0.195
Y42.7 Androgens and anabolic congeners	0.803	0.197
R26.8 Other and unspecified abnormalities of gait and mobility	0.802	0.198
T15-T19 Effects of foreign body entering through natural orifice	0.801	0.199
H35.8 Other specified retinal disorders	0.801	0.199
T90 Sequelae of injuries of head	0.800	0.200
H43-H45 Disorders of vitreous body and globe	0.798	0.202
F30 Manic episode	0.795	0.205
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.794	0.206
Y45.1 Salicylates	0.791	0.209
R63.0 Anorexia	0.790	0.210
F99-F99 Unspecified mental disorder	0.790	0.210
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.789	0.211
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.789	0.211
T91 Sequelae of injuries of neck and trunk	0.787	0.213
T00-T07 Injuries involving multiple body regions	0.786	0.214
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.786	0.214
M88 Paget's disease of bone [osteitis deformans]	0.783	0.217
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.783	0.217
R57 Shock, not elsewhere classified	0.778	0.222
W08 Fall involving other furniture	0.778	0.222
S90-S99 Injuries to the ankle and foot	0.778	0.222
S36 Injury of intra-abdominal organs	0.777	0.223
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.775	0.225
R82 Other abnormal findings in urine	0.775	0.225
W11 Fall on and from ladder	0.774	0.226
Y41 Other systemic anti-infectives and antiparasitics	0.773	0.227
R52 Pain, not elsewhere classified	0.771	0.229
W19.2 School, other institution and public administrative area	0.771	0.229
M70 Soft tissue disorders related to use, overuse and pressure	0.770	0.230
F60.3 Emotionally unstable personality disorder	0.769	0.231
E50-E64 Other nutritional deficiencies	0.767	0.233
W10 Fall on and from stairs and steps	0.763	0.237
M50-M54 Other dorsopathies	0.763	0.237
V95-V97 Air and space transport accidents	0.762	0.238
E14.9 Without complications	0.761	0.239
X60-X84 Intentional self-harm	0.758	0.242
W28 Contact with powered lawn mower	0.757	0.243
R68.0 Hypothermia, not associated with low environmental temperature	0.756	0.244
W22.9 Unspecified place	0.755	0.245
Y45.8 Other analgesics and antipyretics	0.753	0.247
S40-S49 Injuries to the shoulder and upper arm	0.753	0.247
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.750	0.249
F45 Somatoform disorders	0.750	0.250
M88.9 Paget's disease of bone, unspecified	0.750	0.250
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.749	0.251
H43 Disorders of vitreous body	0.748	0.252
E89.3 Postprocedural hypopituitarism	0.748	0.252
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.747	0.253
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.745	0.255
E89.2 Postprocedural hypoparathyroidism	0.745	0.255
H35.4 Peripheral retinal degeneration	0.745	0.255
R64 Cachexia	0.745	0.255
Y46 Antiepileptics and anti-Parkinsonism drugs	0.744	0.256
Y40.6 Rifamycins	0.741	0.258
E13 Other specified diabetes mellitus	0.741	0.259
E78.8 Other disorders of lipoprotein metabolism	0.741	0.259
R72 Abnormality of white blood cells, not elsewhere classified	0.740	0.260
T14.1 Open wound of unspecified body region	0.739	0.261
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.738	0.262
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.738	0.262
T20 Burn and corrosion of head and neck	0.737	0.262
W01 Fall on same level from slipping, tripping and stumbling	0.737	0.262
R61 Hyperhidrosis	0.736	0.264
W06 Fall involving bed	0.736	0.264
H46-H48 Disorders of optic nerve and visual pathways	0.733	0.267
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.733	0.267
X40-X49 Accidental poisoning by and exposure to noxious substances	0.732	0.268
H43.8 Other disorders of vitreous body	0.732	0.268
T31 Burns classified according to extent of body surface involved	0.731	0.269
F43.2 Adjustment disorders	0.731	0.269
D80-D89 Certain disorders involving the immune mechanism	0.731	0.269
Y47 Sedatives, hypnotics and antianxiety drugs	0.730	0.270
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.729	0.271
R63.1 Polydipsia	0.729	0.271
W44.0 Home	0.729	0.271
H35.3 Degeneration of macula and posterior pole	0.728	0.272
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.726	0.274
S22 Fracture of rib(s), sternum and thoracic spine	0.726	0.274
S80-S89 Injuries to the knee and lower leg	0.725	0.275
T66 Unspecified effects of radiation	0.725	0.275
F48 Other neurotic disorders	0.725	0.275
E78.1 Pure hyperglyceridaemia	0.724	0.276
F02 Dementia in other diseases classified elsewhere	0.724	0.276
F43.0 Acute stress reaction	0.724	0.276
X20-X29 Contact with venomous animals and plants	0.724	0.276
Chapter IX Diseases of the circulatory system	0.724	0.276
Y43 Primarily systemic agents	0.723	0.277
R77 Other abnormalities of plasma proteins	0.723	0.277
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.721	0.279
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.721	0.279
V80-V89 Other land transport accidents	0.720	0.279
T92.8 Sequelae of other specified injuries of upper limb	0.720	0.280
R63.8 Other symptoms and signs concerning food and fluid intake	0.719	0.281
I30-I52 Other forms of heart disease	0.719	0.281
E89.4 Postprocedural ovarian failure	0.719	0.281
T70 Effects of air pressure and water pressure	0.718	0.282
F64 Gender identity disorders	0.718	0.282
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283
F70-F79 Mental retardation	0.717	0.283
S12.2 Fracture of other specified cervical vertebra	0.717	0.283
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
S19 Other and unspecified injuries of neck	0.716	0.284
T95 Sequelae of burns, corrosions and frostbite	0.716	0.284
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.716	0.284
E12 Malnutrition-related diabetes mellitus	0.715	0.285
T75 Effects of other external causes	0.714	0.285
R95-R99 Ill-defined and unknown causes of mortality	0.714	0.286
Y35-Y36 Legal intervention and operations of war	0.714	0.286
Y10-Y34 Event of undetermined intent	0.714	0.286
X85-X99 Assault	0.714	0.286
X30-X39 Exposure to forces of nature	0.714	0.286
X00-X09 Exposure to smoke, fire and flames	0.714	0.286
W75-W84 Other accidental threats to breathing	0.714	0.286
W65-W74 Accidental drowning and submersion	0.714	0.286
V98-V99 Other and unspecified transport accidents	0.714	0.286
V90-V94 Water transport accidents	0.714	0.286
V70-V79 Bus occupant injured in transport accident	0.714	0.286
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.714	0.286
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.714	0.286
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.714	0.286
V01-V09 Pedestrian injured in transport accident	0.714	0.286
W45 Foreign body or object entering through skin	0.714	0.286
V10-V19 Pedal cyclist injured in transport accident	0.714	0.286
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.713	0.287
R62 Lack of expected normal physiological development	0.713	0.287
F00.9 Dementia in Alzheimer's disease, unspecified	0.713	0.287
E11.6 With other specified complications	0.712	0.288
E84 Cystic fibrosis	0.711	0.288
E79 Disorders of purine and pyrimidine metabolism	0.711	0.288
E77 Disorders of glycoprotein metabolism	0.711	0.288
E76 Disorders of glycosaminoglycan metabolism	0.711	0.288
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.711	0.288
E72 Other disorders of amino-acid metabolism	0.711	0.288
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.711	0.288
E70 Disorders of aromatic amino-acid metabolism	0.711	0.288
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.711	0.288
X58-X59 Accidental exposure to other and unspecified factors	0.711	0.289
E11.8 With unspecified complications	0.711	0.289
E27 Other disorders of adrenal gland	0.711	0.289
F20.0 Paranoid schizophrenia	0.709	0.291
X10-X19 Contact with heat and hot substances	0.708	0.291
E11.7 With multiple complications	0.708	0.292
E10.1 With ketoacidosis	0.706	0.294
I35 Nonrheumatic aortic valve disorders	0.706	0.294
F31.8 Other bipolar affective disorders	0.706	0.294
W23 Caught, crushed, jammed or pinched in or between objects	0.705	0.295
W17 Other fall from one level to another	0.703	0.297
F38 Other mood [affective] disorders	0.702	0.297
F34 Persistent mood [affective] disorders	0.702	0.297
Y59 Other and unspecified vaccines and biological substances	0.702	0.297
Y58 Bacterial vaccines	0.702	0.297
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.702	0.297
Y50 Central nervous system stimulants, not elsewhere classified	0.702	0.297
T23 Burn and corrosion of wrist and hand	0.702	0.298
M70.6 Trochanteric bursitis	0.702	0.298
T18 Foreign body in alimentary tract	0.701	0.299
E78.6 Lipoprotein deficiency	0.698	0.302
E78.3 Hyperchylomicronaemia	0.698	0.302
F25.9 Schizoaffective disorder, unspecified	0.696	0.304
E10.0 With coma	0.696	0.304
M70.4 Prepatellar bursitis	0.696	0.304
S31 Open wound of abdomen, lower back and pelvis	0.695	0.305
E21.0 Primary hyperparathyroidism	0.694	0.306
F60.8 Other specific personality disorders	0.694	0.306
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.694	0.306
Y53 Agents primarily affecting the gastro-intestinal system	0.693	0.307
M54 Dorsalgia	0.693	0.307
T78 Adverse effects, not elsewhere classified	0.692	0.308
Y45.5 4-Aminophenol derivatives	0.691	0.309
T90.8 Sequelae of other specified injuries of head	0.690	0.310
R85.5 Abnormal microbiological findings	0.690	0.310
Y00-Y09 Assault	0.690	0.310
F80-F89 Disorders of psychological development	0.689	0.311
E29 Testicular dysfunction	0.688	0.312
D86 Sarcoidosis	0.687	0.313
T25.2 Burn of second degree of ankle and foot	0.687	0.313
S36.8 Injury of other intra-abdominal organs	0.686	0.314
E24 Cushing's syndrome	0.686	0.314
E11.4 With neurological complications	0.686	0.314
E74 Other disorders of carbohydrate metabolism	0.686	0.314
Q50-Q56 Congenital malformations of genital organs	0.685	0.314
S30 Superficial injury of abdomen, lower back and pelvis	0.685	0.315
E14.6 With other specified complications	0.684	0.316
M90 Osteopathies in diseases classified elsewhere	0.684	0.316
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.683	0.317
R57.0 Cardiogenic shock	0.683	0.317
E78.9 Disorder of lipoprotein metabolism, unspecified	0.683	0.317
E89.0 Postprocedural hypothyroidism	0.683	0.317
R60 Oedema, not elsewhere classified	0.682	0.318
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.682	0.318
E88.2 Lipomatosis, not elsewhere classified	0.681	0.319
R76 Other abnormal immunological findings in serum	0.681	0.319
T21 Burn and corrosion of trunk	0.681	0.319
R78 Findings of drugs and other substances, not normally found in blood	0.681	0.319
T11 Other injuries of upper limb, level unspecified	0.680	0.319
E10.6 With other specified complications	0.680	0.319
Y40.5 Aminoglycosides	0.680	0.320
W16 Diving or jumping into water causing injury other than drowning or submersion	0.680	0.320
W14 Fall from tree	0.680	0.320
W12 Fall on and from scaffolding	0.680	0.320
W09 Fall involving playground equipment	0.680	0.320
W05 Fall involving wheelchair	0.680	0.320
W04 Fall while being carried or supported by other persons	0.680	0.320
W03 Other fall on same level due to collision with, or pushing by, another person	0.680	0.320
W00 Fall on same level involving ice and snow	0.680	0.320
Y42.1 Thyroid hormones and substitutes	0.679	0.320
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.678	0.322
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.678	0.322
W21 Striking against or struck by sports equipment	0.677	0.323
I33 Acute and subacute endocarditis	0.677	0.323
M60-M63 Disorders of muscles	0.675	0.325
T25.3 Burn of third degree of ankle and foot	0.675	0.325
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.675	0.325
Y45.4 Antirheumatics	0.675	0.325
E10.2 With renal complications	0.674	0.325
Y40.0 Penicillins	0.674	0.326
I42 Cardiomyopathy	0.674	0.326
F12 Mental and behavioural disorders due to use of cannabinoids	0.673	0.326
W46 Contact with hypodermic needle	0.673	0.327
W43 Exposure to vibration	0.673	0.327
W42 Exposure to noise	0.673	0.327
W41 Exposure to high-pressure jet	0.673	0.327
W40 Explosion of other materials	0.673	0.327
W39 Discharge of firework	0.673	0.327
W38 Explosion and rupture of other specified pressurised devices	0.673	0.327
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.673	0.327
W36 Explosion and rupture of gas cylinder	0.673	0.327
W35 Explosion and rupture of boiler	0.673	0.327
W34 Discharge from other and unspecified firearms	0.673	0.327
W33 Rifle, shotgun and larger firearm discharge	0.673	0.327
W32 Handgun discharge	0.673	0.327
W31 Contact with other and unspecified machinery	0.673	0.327
W30 Contact with agricultural machinery	0.673	0.327
W27 Contact with nonpowered hand tool	0.673	0.327
W26 Contact with knife, sword or dagger	0.673	0.327
W24 Contact with lifting and transmission devices, not elsewhere classified	0.673	0.327
W15 Fall from cliff	0.672	0.327
E14.8 With unspecified complications	0.672	0.328
Q80-Q89 Other congenital malformations	0.672	0.328
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.672	0.328
W20 Struck by thrown, projected or falling object	0.672	0.328
S12.9 Fracture of neck, part unspecified	0.672	0.328
M40-M43 Deforming dorsopathies	0.670	0.330
T94 Sequelae of injuries involving multiple and unspecified body regions	0.670	0.330
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.670	0.330
F09 Unspecified organic or symptomatic mental disorder	0.670	0.330
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.670	0.330
Y86 Sequelae of other accidents	0.670	0.330
H55-H59 Other disorders of eye and adnexa	0.669	0.331
R86 Abnormal findings in specimens from male genital organs	0.668	0.331
F25.1 Schizoaffective disorder, depressive type	0.668	0.332
F40 Phobic anxiety disorders	0.668	0.332
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.667	0.332
T74 Maltreatment syndromes	0.667	0.333
T73 Effects of other deprivation	0.667	0.333
T69 Other effects of reduced temperature	0.667	0.333
T67 Effects of heat and light	0.667	0.333
T71 Asphyxiation	0.667	0.333
I35.2 Aortic (valve) stenosis with insufficiency	0.666	0.334
R47-R49 Symptoms and signs involving speech and voice	0.666	0.334
S20 Superficial injury of thorax	0.666	0.334
Y40.9 Systemic antibiotic, unspecified	0.665	0.335
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.664	0.336
H34 Retinal vascular occlusions	0.664	0.336
F68 Other disorders of adult personality and behaviour	0.663	0.337
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.663	0.337
F65 Disorders of sexual preference	0.663	0.337
F63 Habit and impulse disorders	0.663	0.337
F62 Enduring personality changes, not attributable to brain damage and disease	0.663	0.337
F69 Unspecified disorder of adult personality and behaviour	0.663	0.337
F61 Mixed and other personality disorders	0.663	0.337
V20-V29 Motorcycle rider injured in transport accident	0.663	0.337
Y48 Anaesthetics and therapeutic gases	0.662	0.338
Y49.0 Tricyclic and tetracyclic antidepressants	0.662	0.338
T98 Sequelae of other and unspecified effects of external causes	0.661	0.339
E85 Amyloidosis	0.661	0.339
M79 Other soft tissue disorders, not elsewhere classified	0.660	0.340
E78.4 Other hyperlipidaemia	0.660	0.340
H35.9 Retinal disorder, unspecified	0.659	0.341
R58 Haemorrhage, not elsewhere classified	0.658	0.342
F28 Other nonorganic psychotic disorders	0.658	0.342
F24 Induced delusional disorder	0.658	0.342
F21 Schizotypal disorder	0.658	0.342
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.658	0.342
W50-W64 Exposure to animate mechanical forces	0.657	0.343
W18 Other fall on same level	0.657	0.343
E22 Hyperfunction of pituitary gland	0.657	0.343
W13 Fall from, out of or through building or structure	0.656	0.344
W08.0 Home	0.656	0.344
R70.0 Elevated erythrocyte sedimentation rate	0.656	0.344
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.655	0.345
S26 Injury of heart	0.655	0.345
S25 Injury of blood vessels of thorax	0.655	0.345
S24 Injury of nerves and spinal cord at thorax level	0.655	0.345
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.655	0.345
S21 Open wound of thorax	0.655	0.345
M80-M85 Disorders of bone density and structure	0.655	0.345
W22.3 Sports and athletics area	0.653	0.347
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.653	0.347
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.653	0.347
F33.8 Other recurrent depressive disorders	0.653	0.347
F33.4 Recurrent depressive disorder, currently in remission	0.653	0.347
M54.1 Radiculopathy	0.652	0.348
S27.1 Traumatic haemothorax	0.652	0.348
S17 Crushing injury of neck	0.652	0.348
S15 Injury of blood vessels at neck level	0.652	0.348
S11 Open wound of neck	0.652	0.348
S18 Traumatic amputation at neck level	0.652	0.348
S16 Injury of muscle and tendon at neck level	0.652	0.348
F44 Dissociative [conversion] disorders	0.651	0.348
T31.0 Burns involving less than 10% of body surface	0.651	0.349
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.651	0.349
F60.9 Personality disorder, unspecified	0.651	0.349
S12.1 Fracture of second cervical vertebra	0.651	0.349
R26.0 Ataxic gait	0.650	0.350
Y60-Y69 Misadventures to patients during surgical and medical care	0.650	0.350
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.650	0.350
E40-E46 Malnutrition	0.650	0.350
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.649	0.351
E89.8 Other postprocedural endocrine and metabolic disorders	0.649	0.351
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.649	0.351
E89.5 Postprocedural testicular hypofunction	0.649	0.351
E89.1 Postprocedural hypoinsulinaemia	0.649	0.351
R85.7 Abnormal histological findings	0.649	0.351
W11.6 Industrial and construction area	0.649	0.351
T13 Other injuries of lower limb, level unspecified	0.648	0.351
T09 Other injuries of spine and trunk, level unspecified	0.648	0.351
T12.X1 Fracture of lower limb, level unspecified (open)	0.648	0.351
T12.X0 Fracture of lower limb, level unspecified (closed)	0.648	0.351
T12 Fracture of lower limb, level unspecified	0.648	0.351
T10.X1 Fracture of upper limb, level unspecified (open)	0.648	0.351
T10.X0 Fracture of upper limb, level unspecified (closed)	0.648	0.351
T10 Fracture of upper limb, level unspecified	0.648	0.351
T08.X1 Fracture of spine, level unspecified (open)	0.648	0.351
T08.X0 Fracture of spine, level unspecified (closed)	0.648	0.351
T08 Fracture of spine, level unspecified	0.648	0.351
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.648	0.352
D86.9 Sarcoidosis, unspecified	0.648	0.352
R68.8 Other specified general symptoms and signs	0.647	0.353
I33.0 Acute and subacute infective endocarditis	0.646	0.354
E23 Hypofunction and other disorders of pituitary gland	0.645	0.355
T14.6 Injury of tendons and muscles of unspecified body region	0.645	0.355
F31.9 Bipolar affective disorder, unspecified	0.645	0.355
M91-M94 Chondropathies	0.644	0.356
E27.1 Primary adrenocortical insufficiency	0.644	0.356
H47 Other disorders of optic [2nd] nerve and visual pathways	0.643	0.357
F42 Obsessive-compulsive disorder	0.642	0.357
M70.46 Prepatellar bursitis-Lower Leg	0.642	0.358
Q60-Q64 Congenital malformations of the urinary system	0.642	0.358
E10.5 With peripheral circulatory complications	0.641	0.358
F25.0 Schizoaffective disorder, manic type	0.641	0.359
T92.4 Sequelae of injury of nerve of upper limb	0.640	0.360
E10.8 With unspecified complications	0.640	0.360
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.640	0.360
F99 Mental disorder, not otherwise specified	0.639	0.361
M86 Osteomyelitis	0.638	0.362
E11.1 With ketoacidosis	0.637	0.362
I35.9 Aortic valve disorder, unspecified	0.637	0.363
T14.0 Superficial injury of unspecified body region	0.637	0.363
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.637	0.363
S37 Injury of urinary and pelvic organs	0.637	0.363
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.637	0.363
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.637	0.363
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.637	0.363
F23 Acute and transient psychotic disorders	0.637	0.363
Y49.5 Other antipsychotics and neuroleptics	0.637	0.363
R77.8 Other specified abnormalities of plasma proteins	0.636	0.364
T79-T79 Certain early complications of trauma	0.636	0.364
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.635	0.364
E35 Disorders of endocrine glands in diseases classified elsewhere	0.635	0.365
E32 Diseases of thymus	0.635	0.365
E31 Polyglandular dysfunction	0.635	0.365
E30 Disorders of puberty, not elsewhere classified	0.635	0.365
E25 Adrenogenital disorders	0.635	0.365
S00-S09 Injuries to the head	0.635	0.365
E80 Disorders of porphyrin and bilirubin metabolism	0.634	0.366
S12.7 Multiple fractures of cervical spine	0.634	0.366
T02 Fractures involving multiple body regions	0.633	0.367
R54 Senility	0.633	0.367
T92.9 Sequelae of unspecified injury of upper limb	0.633	0.367
S12.20 Fracture of other specified cervical vertebra (closed)	0.633	0.367
I49 Other cardiac arrhythmias	0.632	0.368
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.632	0.368
M72 Fibroblastic disorders	0.632	0.368
E78.0 Pure hypercholesterolaemia	0.632	0.368
R27 Other lack of coordination	0.632	0.368
R59 Enlarged lymph nodes	0.632	0.368
F31.7 Bipolar affective disorder, currently in remission	0.631	0.368
I35.8 Other aortic valve disorders	0.631	0.369
I42.2 Other hypertrophic cardiomyopathy	0.631	0.369
E10.4 With neurological complications	0.631	0.369
Y51 Drugs primarily affecting the autonomic nervous system	0.631	0.369
S14 Injury of nerves and spinal cord at neck level	0.631	0.369
R52.0 Acute pain	0.631	0.369
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.629	0.371
S99 Other and unspecified injuries of ankle and foot	0.629	0.371
S50-S59 Injuries to the elbow and forearm	0.629	0.371
F05.1 Delirium superimposed on dementia	0.629	0.371
F05.0 Delirium not superimposed on dementia, so described	0.629	0.371
T91.1 Sequelae of fracture of spine	0.628	0.372
F29 Unspecified nonorganic psychosis	0.627	0.372
W07 Fall involving chair	0.627	0.373
T90.5 Sequelae of intracranial injury	0.627	0.373
F31.6 Bipolar affective disorder, current episode mixed	0.627	0.373
F05.8 Other delirium	0.627	0.373
W28.9 Unspecified place	0.626	0.373
F30.9 Manic episode, unspecified	0.626	0.374
R63.6 Insufficient intake of food and water due to self neglect	0.626	0.374
R63.3 Feeding difficulties and mismanagement	0.626	0.374
R63.2 Polyphagia	0.626	0.374
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.626	0.374
I36 Nonrheumatic tricuspid valve disorders	0.625	0.375
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.625	0.375

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations