TreeWAS – Variant ID: rs12595433

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R01.1 Cardiac murmur, unspecified	0.040	0.960	0.000
R63.0 Anorexia	0.023	0.977	0.000
K51 Ulcerative colitis	0.000	0.980	0.020
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.980	0.020
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.980	0.020
K51.4 Pseudopolyposis of colon	0.000	0.981	0.019
K51.2 Ulcerative (chronic) proctitis	0.000	0.982	0.018
K51.8 Other ulcerative colitis	0.000	0.982	0.018
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.985	0.015
Z90.0 Acquired absence of part of head and neck	0.000	0.988	0.012
R01 Cardiac murmurs and other cardiac sounds	0.012	0.988	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.989	0.011
K51.5 Mucosal proctocolitis	0.000	0.989	0.011
Z90.7 Acquired absence of genital organ(s)	0.000	0.990	0.010
R01.2 Other cardiac sounds	0.009	0.991	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.008	0.992	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.008	0.992	0.000
S43.0 Dislocation of shoulder joint	0.000	0.992	0.008
S06.3 Focal brain injury	0.007	0.993	0.000
S06 Intracranial injury	0.007	0.993	0.000
R01.0 Benign and innocent cardiac murmurs	0.006	0.993	0.000
S06.5 Traumatic subdural haemorrhage	0.006	0.994	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.006	0.994	0.000
S06.2 Diffuse brain injury	0.006	0.994	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.006	0.994	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.994	0.006
S06.0 Concussion	0.006	0.994	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.006	0.994	0.000
S06.00 Concussion (without open intracranial wound)	0.006	0.994	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.005	0.995	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.005	0.995	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.995	0.005
M25.86 Other specified joint disorders (Lower leg)	0.005	0.995	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.000	0.995	0.005
S06.7 Intracranial injury with prolonged coma	0.005	0.995	0.000
S06.1 Traumatic cerebral oedema	0.005	0.995	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.005	0.995	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.005	0.995	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.005	0.995	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.995	0.005
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.995	0.005
S06.4 Epidural haemorrhage	0.005	0.995	0.000
S06.9 Intracranial injury, unspecified	0.005	0.995	0.000
S06.01 Concussion (with open intracranial wound)	0.004	0.995	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.004	0.995	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.995	0.005
E11.4 With neurological complications	0.000	0.996	0.004
S06.8 Other intracranial injuries	0.004	0.996	0.000
Y45.0 Opioids and related analgesics	0.000	0.996	0.004
Z90.6 Acquired absence of other parts of urinary tract	0.000	0.996	0.004
F45.8 Other somatoform disorders	0.004	0.996	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.996	0.004
C48.2 Peritoneum, unspecified	0.004	0.996	0.000
S43.1 Dislocation of acromioclavicular joint	0.000	0.996	0.004
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.996	0.004
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.004	0.996	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.004	0.996	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.004	0.996	0.000
M79.70 Fibromyalgia (Multiple sites)	0.004	0.996	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.004	0.996	0.000
M25.47 Effusion of joint (Ankle and foot)	0.004	0.996	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.004	0.996	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.996	0.004
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.996	0.004
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.996	0.004
S43.2 Dislocation of sternoclavicular joint	0.000	0.996	0.004
S06.41 Epidural haemorrhage (with open intracranial wound)	0.003	0.996	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.003	0.996	0.000
S43.4 Sprain and strain of shoulder joint	0.000	0.996	0.003
Z39.0 Care and examination immediately after delivery	0.004	0.996	0.000
Z90.8 Acquired absence of other organs	0.000	0.996	0.004
M77.47 Metatarsalgia-Ankle/Foot	0.004	0.996	0.000
E10.4 With neurological complications	0.004	0.996	0.000
T39.0 Salicylates	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.997	0.003
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.997	0.003
H71 Cholesteatoma of middle ear	0.000	0.997	0.003
S06.81 Other intracranial injuries (with open intracranial wound)	0.003	0.997	0.000
T36.0 Penicillins	0.000	0.997	0.003
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.003	0.997	0.000
O42 Premature rupture of membranes	0.003	0.997	0.000
Z90.5 Acquired absence of kidney	0.000	0.997	0.003
C49.3 Connective and soft tissue of thorax	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
T36 Poisoning by systemic antibiotics	0.000	0.997	0.003
T45.0 Antiallergic and antiemetic drugs	0.000	0.997	0.003
O32.2 Maternal care for transverse and oblique lie	0.003	0.997	0.000
T42.4 Benzodiazepines	0.000	0.997	0.003
D41.0 Kidney	0.003	0.997	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.003
M76.67 Achilles tendinitis (Ankle and foot)	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
F81.9 Developmental disorder of scholastic skills, unspecified	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
Z63.4 Disappearance and death of family member	0.003	0.997	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.003	0.997	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.003	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.003
Z90.1 Acquired absence of breast(s)	0.000	0.997	0.003
O32.9 Maternal care for malpresentation of foetus, unspecified	0.003	0.997	0.000
O32.4 Maternal care for high head at term	0.003	0.997	0.000
O47 False labour	0.003	0.997	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.003
T39.2 Pyrazolone derivatives	0.000	0.997	0.003
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
Z90.3 Acquired absence of part of stomach	0.000	0.997	0.003
M25.45 Effusion of joint (Pelvic region and thigh)	0.003	0.997	0.000
H57.1 Ocular pain	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.997	0.003
M25.4 Effusion of joint	0.003	0.997	0.000
R63 Symptoms and signs concerning food and fluid intake	0.003	0.997	0.000
M25.43 Effusion of joint (Forearm)	0.002	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.997	0.002
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.997	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.998	0.002
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.4 Tetracyclines	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
R63.5 Abnormal weight gain	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.002	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.002	0.998	0.000
M25.83 Other specified joint disorders (Forearm)	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.002
J84 Other interstitial pulmonary diseases	0.002	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.002	0.998	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.002	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
K05.1 Chronic gingivitis	0.002	0.998	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.002	0.998	0.000
J03 Acute tonsillitis	0.000	0.998	0.002
M25.55 Pain in joint (Pelvic region and thigh)	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
C49.4 Connective and soft tissue of abdomen	0.002	0.998	0.000
F32.0 Mild depressive episode	0.000	0.998	0.002
J84.8 Other specified interstitial pulmonary diseases	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
M25.41 Effusion of joint (Shoulder region)	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
O32.6 Maternal care for compound presentation	0.002	0.998	0.000
T42.1 Iminostilbenes	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998	0.000
T50.8 Diagnostic agents	0.000	0.998	0.002
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.002
M25.49 Effusion of joint (Site unspecified)	0.002	0.998	0.000
M25.48 Effusion of joint (Other)	0.002	0.998	0.000
R63.2 Polyphagia	0.002	0.998	0.000
T45.5 Anticoagulants	0.000	0.998	0.002
Z56.0 Unemployment, unspecified	0.002	0.998	0.000
M25.8 Other specified joint disorders	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
O47.0 False labour before 37 completed weeks of gestation	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
F45 Somatoform disorders	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
O48 Prolonged pregnancy	0.002	0.998	0.000
O45 Premature separation of placenta [abruptio placentae]	0.002	0.998	0.000
D34 Benign neoplasm of thyroid gland	0.000	0.998	0.002
F45.3 Somatoform autonomic dysfunction	0.002	0.998	0.000
T42.3 Barbiturates	0.000	0.998	0.002
X41.9 Unspecified place	0.000	0.998	0.002
Y85.0 Sequelae of motor-vehicle accident	0.000	0.998	0.002
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.002	0.998	0.000
O45.9 Premature separation of placenta, unspecified	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
G50.1 Atypical facial pain	0.002	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.002	0.998	0.000
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
Z04.1 Examination and observation following transport accident	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.000	0.998	0.002
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.998	0.002
G51.9 Disorder of facial nerve, unspecified	0.002	0.998	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.000	0.998	0.002
J03.0 Streptococcal tonsillitis	0.000	0.998	0.002
K63.2 Fistula of intestine	0.000	0.998	0.002
R63.3 Feeding difficulties and mismanagement	0.002	0.998	0.000
R63.1 Polydipsia	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
O31 Complications specific to multiple gestation	0.002	0.998	0.000
R63.6 Insufficient intake of food and water due to self neglect	0.002	0.998	0.000
G51.0 Bell's palsy	0.002	0.998	0.000
K00.9 Disorder of tooth development, unspecified	0.002	0.998	0.000
M77.4 Metatarsalgia	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.998	0.002
Z29.0 Isolation	0.000	0.998	0.002
E27 Other disorders of adrenal gland	0.000	0.998	0.002
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.002	0.998	0.000
Z56.6 Other physical and mental strain related to work	0.002	0.998	0.000
M71.38 Other bursal cyst (Other)	0.000	0.998	0.002
C44.9 Malignant neoplasm of skin, unspecified	0.002	0.998	0.000
G50.0 Trigeminal neuralgia	0.002	0.998	0.000
J04.0 Acute laryngitis	0.000	0.998	0.002
O43 Placental disorders	0.002	0.998	0.000
O33 Maternal care for known or suspected disproportion	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
F45.4 Persistent somatoform pain disorder	0.002	0.998	0.000
O40 Polyhydramnios	0.002	0.998	0.000
Z56 Problems related to employment and unemployment	0.002	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.998	0.000
M25.82 Other specified joint disorders (Upper arm)	0.002	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.998	0.000
F45.0 Somatisation disorder	0.002	0.998	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
F45.1 Undifferentiated somatoform disorder	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
G45.3 Amaurosis fugax	0.000	0.998	0.002
O45.8 Other premature separation of placenta	0.002	0.998	0.000
O45.0 Premature separation of placenta with coagulation defect	0.002	0.998	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.998	0.000
M25.44 Effusion of joint (Hand)	0.002	0.998	0.000
M76.6 Achilles tendinitis	0.002	0.998	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.002	0.998	0.000
S14.3 Injury of brachial plexus	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.002
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.002	0.998	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
M25.42 Effusion of joint (Upper arm)	0.001	0.998	0.000
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
F45.9 Somatoform disorder, unspecified	0.002	0.998	0.000
O32.0 Maternal care for unstable lie	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.001
T47.7 Emetics	0.000	0.998	0.001
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.001
T47.5 Digestants	0.000	0.998	0.001
T47.3 Saline and osmotic laxatives	0.000	0.998	0.001
T47.2 Stimulant laxatives	0.000	0.998	0.001
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.001
Z58 Problems related to physical environment	0.002	0.998	0.000
H16.0 Corneal ulcer	0.000	0.998	0.002
R63.8 Other symptoms and signs concerning food and fluid intake	0.002	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.998	0.002
E27.2 Addisonian crisis	0.000	0.998	0.002
O31.8 Other complications specific to multiple gestation	0.001	0.998	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.001	0.998	0.000
F81 Specific developmental disorders of scholastic skills	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.001	0.998	0.000
O31.0 Papyraceous foetus	0.001	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
D51 Vitamin B12 deficiency anaemia	0.000	0.998	0.002
S14 Injury of nerves and spinal cord at neck level	0.000	0.998	0.002
C48.1 Specified parts of peritoneum	0.001	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
O43.8 Other placental disorders	0.002	0.998	0.000
M77.49 Metatarsalgia-Site unspec	0.001	0.998	0.000
M77.48 Metatarsalgia-Other	0.001	0.998	0.000
M77.46 Metatarsalgia-Lower Leg	0.001	0.998	0.000
M77.45 Metatarsalgia-Pelvic/Thigh	0.001	0.998	0.000
M77.44 Metatarsalgia-Hand	0.001	0.998	0.000
M77.43 Metatarsalgia-Forearm	0.001	0.998	0.000
M77.42 Metatarsalgia-Upper arm	0.001	0.998	0.000
M77.41 Metatarsalgia-Shldr region	0.001	0.998	0.000
M77.40 Metatarsalgia-Mult sites	0.001	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.001
E27.0 Other adrenocortical overactivity	0.000	0.998	0.001
J84.1 Other interstitial pulmonary diseases with fibrosis	0.002	0.998	0.000
N30.3 Trigonitis	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
F43.1 Posttraumatic stress disorder	0.000	0.998	0.002
O43.1 Malformation of placenta	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.001
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
O33.8 Maternal care for disproportion of other origin	0.001	0.998	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.001	0.998	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.001	0.998	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.001	0.998	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.001	0.998	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.001	0.998	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.001	0.998	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.001	0.998	0.000
O43.2 Morbidly adherent placenta	0.001	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.001
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.001
T46.7 Peripheral vasodilators	0.000	0.998	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.001
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.001
T47.4 Other laxatives	0.000	0.998	0.001
Z56.5 Uncongenial work	0.001	0.998	0.000
Z56.4 Discord with boss and workmates	0.001	0.998	0.000
Z56.2 Threat of job loss	0.001	0.998	0.000
Z56.1 Change of job	0.001	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.001	0.998	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.000	0.998	0.002
D63 Anaemia in chronic diseases classified elsewhere	0.002	0.998	0.000
O30 Multiple gestation	0.002	0.998	0.000
Z39 Postpartum care and examination	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
S29.9 Unspecified injury of thorax	0.002	0.998	0.000
Z56.7 Other and unspecified problems related to employment	0.001	0.998	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.002	0.998	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.002	0.998	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
H02.9 Disorder of eyelid, unspecified	0.002	0.998	0.000
M79.7 Fibromyalgia	0.002	0.998	0.000
Z63.9 Problem related to primary support group, unspecified	0.001	0.998	0.000
Z63.3 Absence of family member	0.001	0.998	0.000
Z63.2 Inadequate family support	0.001	0.998	0.000
Z63.1 Problems in relationship with parents and in-laws	0.001	0.998	0.000
T17 Foreign body in respiratory tract	0.002	0.998	0.000
F45.2 Hypochondriacal disorder	0.001	0.998	0.000
H31.8 Other specified disorders of choroid	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.000	0.998	0.002
M95.0 Acquired deformity of nose	0.000	0.998	0.002
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.001	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.001	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.001	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.001	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.001	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.001	0.998	0.000
M76.69 Achilles tendinitis-Site unspec	0.001	0.998	0.000
M76.68 Achilles tendinitis-Other	0.001	0.998	0.000
M76.65 Achilles tendinitis-Pelvic/Thigh	0.001	0.998	0.000
M76.64 Achilles tendinitis-Hand	0.001	0.998	0.000
M76.63 Achilles tendinitis-Forearm	0.001	0.998	0.000
M76.62 Achilles tendinitis-Upper arm	0.001	0.998	0.000
M76.61 Achilles tendinitis-Shldr region	0.001	0.998	0.000
M76.60 Achilles tendinitis (Multiple sites)	0.001	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.998	0.002
O43.9 Placental disorder, unspecified	0.001	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.000	0.998	0.001
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.998	0.001
T17.3 Foreign body in larynx	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.001
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Z56.3 Stressful work schedule	0.001	0.998	0.000
Z90.2 Acquired absence of lung [part of]	0.000	0.998	0.001
G50 Disorders of trigeminal nerve	0.002	0.998	0.000
S12 Fracture of neck	0.000	0.998	0.001
S12.71 Multiple fractures of cervical spine (open)	0.000	0.998	0.001
S62.50 Fracture of thumb (closed)	0.000	0.998	0.001
C48.0 Retroperitoneum	0.001	0.998	0.000
O43.0 Placental transfusion syndromes	0.001	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.001
Z58.9 Problem related to physical environment, unspecified	0.001	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.001	0.998	0.000
Z58.4 Exposure to radiation	0.001	0.998	0.000
Z58.3 Exposure to soil pollution	0.001	0.998	0.000
Z58.2 Exposure to water pollution	0.001	0.998	0.000
Z58.0 Exposure to noise	0.001	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.001	0.998	0.000
O44 Placenta praevia	0.001	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.999	0.001
K00.6 Disturbances in tooth eruption	0.001	0.999	0.000
Z39.2 Routine postpartum follow-up	0.001	0.999	0.000
Z63.8 Other specified problems related to primary support group	0.001	0.999	0.000
M76.66 Achilles tendinitis (Lower leg)	0.001	0.999	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.999	0.001
D51.2 Transcobalamin II deficiency	0.000	0.999	0.001
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.999	0.001
F81.8 Other developmental disorders of scholastic skills	0.001	0.999	0.000
F81.3 Mixed disorder of scholastic skills	0.001	0.999	0.000
F81.2 Specific disorder of arithmetical skills	0.001	0.999	0.000
F81.1 Specific spelling disorder	0.001	0.999	0.000
F81.0 Specific reading disorder	0.001	0.999	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.001	0.999	0.000
K00.8 Other disorders of tooth development	0.001	0.999	0.000
D59.1 Other autoimmune haemolytic anaemias	0.001	0.999	0.000
H57.0 Anomalies of pupillary function	0.000	0.999	0.001
S14.6 Injury of other and unspecified nerves of neck	0.000	0.999	0.001
S14.5 Injury of cervical sympathetic nerves	0.000	0.999	0.001
S14.4 Injury of peripheral nerves of neck	0.000	0.999	0.001
S14.2 Injury of nerve root of cervical spine	0.000	0.999	0.001
S14.0 Concussion and oedema of cervical spinal cord	0.000	0.999	0.001
Z58.5 Exposure to other pollution	0.001	0.999	0.000
K65.9 Peritonitis, unspecified	0.000	0.999	0.001
S12.0 Fracture of first cervical vertebra	0.000	0.999	0.001
S20.1 Other and unspecified superficial injuries of breast	0.000	0.999	0.001
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.999	0.001
T40.8 Lysergide [LSD]	0.000	0.999	0.001
T40.7 Cannabis (derivatives)	0.000	0.999	0.001
T40.5 Cocaine	0.000	0.999	0.001
T40.3 Methadone	0.000	0.999	0.001
T40.1 Heroin	0.000	0.999	0.001
T40.0 Opium	0.000	0.999	0.001
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
D63.1 Anaemia in other chronic diseases classified elsewhere	0.001	0.999	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.999	0.001
O30.9 Multiple gestation, unspecified	0.001	0.999	0.000
O30.8 Other multiple gestation	0.001	0.999	0.000
O30.2 Quadruplet pregnancy	0.001	0.999	0.000
O30.1 Triplet pregnancy	0.001	0.999	0.000
S12.9 Fracture of neck, part unspecified	0.000	0.999	0.001
T13.0 Superficial injury of lower limb, level unspecified	0.001	0.999	0.000
T40.6 Other and unspecified narcotics	0.000	0.999	0.001
O46 Antepartum haemorrhage, not elsewhere classified	0.001	0.999	0.000
A16.8 Other respiratory tuberculosis, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.7 Primary respiratory tuberculosis without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.4 Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.3 Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.1 Tuberculosis of lung, bacteriological and histological examination not done	0.001	0.999	0.000
A16.0 Tuberculosis of lung, bacteriologically and histologically negative	0.001	0.999	0.000
T17.4 Foreign body in trachea	0.001	0.999	0.000
T17.1 Foreign body in nostril	0.001	0.999	0.000
T17.0 Foreign body in nasal sinus	0.001	0.999	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.999	0.001
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.001	0.999	0.000
C46 Kaposi's sarcoma	0.001	0.999	0.000
K00 Disorders of tooth development and eruption	0.001	0.999	0.000
T16 Foreign body in ear	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations