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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13398848
log Bayes Factor = 1.1051
Chromosome 2   position 84,245,168  (GRCh37) Explore rs13398848 on Ensembl!
Variant rs13398848 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.921 0.079 0.000
I25 Chronic ischaemic heart disease
0.917 0.083 0.000
Chapter IX Diseases of the circulatory system
0.915 0.085 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.909 0.091 0.000
I20 Angina pectoris
0.901 0.099 0.000
I20.9 Angina pectoris, unspecified
0.879 0.121 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.878 0.122 0.000
I30-I52 Other forms of heart disease
0.871 0.129 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.852 0.148 0.000
# Top node
0.843 0.157 0.000
Chapter I Certain infectious and parasitic diseases
0.830 0.170 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.828 0.172 0.000
I71 Aortic aneurysm and dissection
0.819 0.181 0.000
I45 Other conduction disorders
0.819 0.181 0.000
I31 Other diseases of pericardium
0.803 0.197 0.000
A30-A49 Other bacterial diseases
0.798 0.202 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.790 0.210 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.784 0.216 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.781 0.219 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.774 0.226 0.000
L90 Atrophic disorders of skin
0.773 0.227 0.000
I95 Hypotension
0.773 0.227 0.000
B35-B49 Mycoses
0.773 0.227 0.000
L90.5 Scar conditions and fibrosis of skin
0.767 0.233 0.000
I22 Subsequent myocardial infarction
0.755 0.245 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.751 0.249 0.000
Chapter XIV Diseases of the genitourinary system
0.749 0.251 0.000
N17-N19 Renal failure
0.745 0.255 0.000
I35 Nonrheumatic aortic valve disorders
0.744 0.256 0.000
I74 Arterial embolism and thrombosis
0.737 0.263 0.000
I31.3 Pericardial effusion (noninflammatory)
0.736 0.264 0.000
A41 Other septicaemia
0.735 0.265 0.000
I20.1 Angina pectoris with documented spasm
0.730 0.270 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.728 0.272 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.727 0.273 0.000
I45.1 Other and unspecified right bundle-branch block
0.724 0.276 0.000
I27 Other pulmonary heart diseases
0.722 0.278 0.000
B37 Candidiasis
0.722 0.278 0.000
I44 Atrioventricular and left bundle-branch block
0.722 0.278 0.000
L85 Other epidermal thickening
0.718 0.282 0.000
Chapter II Neoplasms
0.708 0.292 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.702 0.298 0.000
I95.9 Hypotension, unspecified
0.700 0.300 0.000
N19 Unspecified renal failure
0.698 0.302 0.000
I30 Acute pericarditis
0.698 0.302 0.000
I45.2 Bifascicular block
0.697 0.303 0.000
I25.2 Old myocardial infarction
0.696 0.304 0.000
I20.8 Other forms of angina pectoris
0.694 0.306 0.000
B37.9 Candidiasis, unspecified
0.692 0.308 0.000
A49 Bacterial infection of unspecified site
0.691 0.309 0.000
Chapter VI Diseases of the nervous system
0.690 0.310 0.000
N17 Acute renal failure
0.690 0.310 0.000
B95-B98 Bacterial, viral and other infectious agents
0.689 0.311 0.000
E70-E90 Metabolic disorders
0.684 0.316 0.000
S00-S09 Injuries to the head
0.682 0.318 0.000
C15-C26 Malignant neoplasms of digestive organs
0.681 0.319 0.000
N18 Chronic renal failure
0.680 0.320 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.679 0.321 0.000
I71.0 Dissection of aorta [any part]
0.678 0.321 0.000
I51 Complications and ill-defined descriptions of heart disease
0.673 0.327 0.000
Chapter VIII Diseases of the ear and mastoid process
0.672 0.328 0.000
I25.3 Aneurysm of heart
0.670 0.329 0.000
I38 Endocarditis, valve unspecified
0.667 0.333 0.000
I78 Diseases of capillaries
0.665 0.335 0.000
E50-E64 Other nutritional deficiencies
0.665 0.335 0.000
S90-S99 Injuries to the ankle and foot
0.662 0.337 0.000
L82 Seborrhoeic keratosis
0.661 0.339 0.000
I23 Certain current complications following acute myocardial infarction
0.660 0.340 0.000
I25.6 Silent myocardial ischaemia
0.657 0.342 0.000
I25.4 Coronary artery aneurysm
0.657 0.342 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.657 0.342 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.657 0.343 0.000
I00-I02 Acute rheumatic fever
0.656 0.344 0.000
I35.0 Aortic (valve) stenosis
0.656 0.344 0.000
I44.2 Atrioventricular block, complete
0.656 0.344 0.000
I95.1 Orthostatic hypotension
0.655 0.345 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.655 0.345 0.000
I72 Other aneurysm
0.654 0.346 0.000
G90-G99 Other disorders of the nervous system
0.654 0.346 0.000
I27.0 Primary pulmonary hypertension
0.653 0.347 0.000
I46 Cardiac arrest
0.652 0.348 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.649 0.351 0.000
T66-T78 Other and unspecified effects of external causes
0.647 0.353 0.000
I45.6 Preexcitation syndrome
0.644 0.356 0.000
E83 Disorders of mineral metabolism
0.643 0.357 0.000
I31.9 Disease of pericardium, unspecified
0.638 0.362 0.000
C18 Malignant neoplasm of colon
0.637 0.363 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.635 0.365 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.635 0.365 0.000
B99-B99 Other infectious diseases
0.634 0.366 0.000
S40-S49 Injuries to the shoulder and upper arm
0.631 0.369 0.000
Chapter XXII Codes for special purposes
0.631 0.369 0.000
N17.9 Acute renal failure, unspecified
0.629 0.371 0.000
A46 Erysipelas
0.628 0.372 0.000
I77 Other disorders of arteries and arterioles
0.628 0.372 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.626 0.374 0.000
L91 Hypertrophic disorders of skin
0.625 0.375 0.000
I52 Other heart disorders in diseases classified elsewhere
0.625 0.375 0.000
I48 Atrial fibrillation and flutter
0.625 0.375 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.625 0.375 0.000
I41 Myocarditis in diseases classified elsewhere
0.625 0.375 0.000
I40 Acute myocarditis
0.625 0.375 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.625 0.375 0.000
I37 Pulmonary valve disorders
0.625 0.375 0.000
I36 Nonrheumatic tricuspid valve disorders
0.625 0.375 0.000
I32 Pericarditis in diseases classified elsewhere
0.625 0.375 0.000
L85.9 Epidermal thickening, unspecified
0.625 0.375 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.624 0.376 0.000
S00 Superficial injury of head
0.623 0.377 0.000
I51.9 Heart disease, unspecified
0.620 0.380 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.618 0.382 0.000
N00-N08 Glomerular diseases
0.618 0.382 0.000
A41.8 Other specified septicaemia
0.618 0.382 0.000
B37.8 Candidiasis of other sites
0.617 0.383 0.000
L85.8 Other specified epidermal thickening
0.615 0.385 0.000
S20-S29 Injuries to the thorax
0.614 0.386 0.000
E20-E35 Disorders of other endocrine glands
0.614 0.386 0.000
N99-N99 Other disorders of the genitourinary system
0.613 0.387 0.000
I20.0 Unstable angina
0.612 0.388 0.000
E83.5 Disorders of calcium metabolism
0.612 0.388 0.000
A80-A89 Viral infections of the central nervous system
0.610 0.390 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.609 0.391 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.607 0.393 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.605 0.395 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.604 0.396 0.000
I99 Other and unspecified disorders of circulatory system
0.604 0.396 0.000
N25-N29 Other disorders of kidney and ureter
0.601 0.398 0.000
S60-S69 Injuries to the wrist and hand
0.601 0.399 0.000
I27.2 Other secondary pulmonary hypertension
0.599 0.401 0.000
I33 Acute and subacute endocarditis
0.598 0.402 0.000
B35 Dermatophytosis
0.596 0.404 0.000
G93 Other disorders of brain
0.595 0.405 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.595 0.405 0.000
B65-B83 Helminthiases
0.595 0.405 0.000
B50-B64 Protozoal diseases
0.595 0.405 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.595 0.405 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.595 0.405 0.000
A75-A79 Rickettsioses
0.595 0.405 0.000
A70-A74 Other diseases caused by chlamydiae
0.595 0.405 0.000
A65-A69 Other spirochaetal diseases
0.595 0.405 0.000
A20-A28 Certain zoonotic bacterial diseases
0.595 0.405 0.000
A15-A19 Tuberculosis
0.595 0.405 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.594 0.406 0.000
N30-N39 Other diseases of urinary system
0.592 0.408 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.592 0.408 0.000
C18.9 Colon, unspecified
0.588 0.412 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.587 0.413 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.587 0.413 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.587 0.413 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.587 0.413 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.587 0.413 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.587 0.413 0.000
I45.9 Conduction disorder, unspecified
0.587 0.413 0.000
I45.8 Other specified conduction disorders
0.587 0.413 0.000
I45.5 Other specified heart block
0.587 0.413 0.000
I45.4 Nonspecific intraventricular block
0.587 0.413 0.000
I45.3 Trifascicular block
0.587 0.413 0.000
I45.0 Right fascicular block
0.587 0.413 0.000
I25.5 Ischaemic cardiomyopathy
0.586 0.414 0.000
L50-L54 Urticaria and erythema
0.585 0.415 0.000
I35.1 Aortic (valve) insufficiency
0.584 0.415 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.584 0.416 0.000
N18.5 Chronic kidney disease, stage 5
0.583 0.417 0.000
B15-B19 Viral hepatitis
0.583 0.417 0.000
I21 Acute myocardial infarction
0.583 0.417 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.583 0.417 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.581 0.419 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.579 0.421 0.000
I31.8 Other specified diseases of pericardium
0.576 0.424 0.000
I31.2 Haemopericardium, not elsewhere classified
0.576 0.424 0.000
I31.1 Chronic constrictive pericarditis
0.576 0.424 0.000
I31.0 Chronic adhesive pericarditis
0.576 0.424 0.000
N18.4 Chronic kidney disease, stage 4
0.575 0.425 0.000
I30.9 Acute pericarditis, unspecified
0.573 0.427 0.000
S70-S79 Injuries to the hip and thigh
0.573 0.427 0.000
C18.2 Ascending colon
0.573 0.427 0.000
A48 Other bacterial diseases, not elsewhere classified
0.572 0.428 0.000
A44 Bartonellosis
0.572 0.428 0.000
A43 Nocardiosis
0.572 0.428 0.000
A42 Actinomycosis
0.572 0.428 0.000
A40 Streptococcal septicaemia
0.572 0.428 0.000
A39 Meningococcal infection
0.572 0.428 0.000
A37 Whooping cough
0.572 0.428 0.000
A36 Diphtheria
0.572 0.428 0.000
A32 Listeriosis
0.572 0.428 0.000
A31 Infection due to other mycobacteria
0.572 0.428 0.000
A30 Leprosy [Hansen's disease]
0.572 0.428 0.000
A38 Scarlet fever
0.572 0.428 0.000
A35 Other tetanus
0.572 0.428 0.000
A34 Obstetrical tetanus
0.572 0.428 0.000
A33 Tetanus neonatorum
0.572 0.428 0.000
C64-C68 Malignant neoplasms of urinary tract
0.572 0.428 0.000
Q50-Q56 Congenital malformations of genital organs
0.571 0.429 0.000
A49.8 Other bacterial infections of unspecified site
0.571 0.429 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.571 0.429 0.000
L40-L45 Papulosquamous disorders
0.568 0.432 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.568 0.432 0.000
H65-H75 Diseases of middle ear and mastoid
0.568 0.432 0.000
L10-L14 Bullous disorders
0.567 0.433 0.000
I70 Atherosclerosis
0.566 0.433 0.000
I44.0 Atrioventricular block, first degree
0.566 0.434 0.000
Q60-Q64 Congenital malformations of the urinary system
0.565 0.434 0.000
I25.1 Atherosclerotic heart disease
0.565 0.435 0.000
I51.4 Myocarditis, unspecified
0.564 0.436 0.000
S00.3 Superficial injury of nose
0.564 0.436 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.564 0.436 0.000
N18.2 Chronic kidney disease, stage 2
0.563 0.437 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.563 0.437 0.000
N17.0 Acute renal failure with tubular necrosis
0.562 0.438 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.562 0.438 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.562 0.438 0.000
L94 Other localised connective tissue disorders
0.562 0.438 0.000
L93 Lupus erythematosus
0.562 0.438 0.000
L87 Transepidermal elimination disorders
0.562 0.438 0.000
L88 Pyoderma gangrenosum
0.562 0.438 0.000
L86 Keratoderma in diseases classified elsewhere
0.562 0.438 0.000
L83 Acanthosis nigricans
0.562 0.438 0.000
L80 Vitiligo
0.562 0.438 0.000
D00-D09 In situ neoplasms
0.562 0.438 0.000
N18.0 End-stage renal disease
0.562 0.438 0.000
I28 Other diseases of pulmonary vessels
0.560 0.440 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.559 0.441 0.000
Q80-Q89 Other congenital malformations
0.558 0.442 0.000
N35 Urethral stricture
0.557 0.443 0.000
G70-G73 Diseases of myoneural junction and muscle
0.557 0.443 0.000
T78 Adverse effects, not elsewhere classified
0.556 0.444 0.000
I05-I09 Chronic rheumatic heart diseases
0.556 0.444 0.000
T33-T35 Frostbite
0.555 0.445 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.555 0.445 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.555 0.445 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.555 0.445 0.000
T00-T07 Injuries involving multiple body regions
0.555 0.445 0.000
S10-S19 Injuries to the neck
0.555 0.445 0.000
L90.9 Atrophic disorder of skin, unspecified
0.554 0.445 0.000
L90.8 Other atrophic disorders of skin
0.554 0.445 0.000
L90.6 Striae atrophicae
0.554 0.445 0.000
L90.4 Acrodermatitis chronica atrophicans
0.554 0.445 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.554 0.445 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.554 0.445 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.554 0.445 0.000
I95.8 Other hypotension
0.554 0.446 0.000
I95.2 Hypotension due to drugs
0.554 0.446 0.000
I95.0 Idiopathic hypotension
0.554 0.446 0.000
B48 Other mycoses, not elsewhere classified
0.554 0.446 0.000
B47 Mycetoma
0.554 0.446 0.000
B46 Zygomycosis
0.554 0.446 0.000
B45 Cryptococcosis
0.554 0.446 0.000
B44 Aspergillosis
0.554 0.446 0.000
B43 Chromomycosis and phaeomycotic abscess
0.554 0.446 0.000
B42 Sporotrichosis
0.554 0.446 0.000
B41 Paracoccidioidomycosis
0.554 0.446 0.000
B40 Blastomycosis
0.554 0.446 0.000
B39 Histoplasmosis
0.554 0.446 0.000
B38 Coccidioidomycosis
0.554 0.446 0.000
B36 Other superficial mycoses
0.554 0.446 0.000
B49 Unspecified mycosis
0.554 0.446 0.000
M45-M49 Spondylopathies
0.554 0.446 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.554 0.446 0.000
S50-S59 Injuries to the elbow and forearm
0.552 0.448 0.000
A49.9 Bacterial infection, unspecified
0.552 0.448 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.550 0.450 0.000
I73 Other peripheral vascular diseases
0.550 0.450 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.549 0.451 0.000
M80-M85 Disorders of bone density and structure
0.549 0.451 0.000
N18.8 Other chronic renal failure
0.548 0.452 0.000
L20-L30 Dermatitis and eczema
0.547 0.453 0.000
E53 Deficiency of other B group vitamins
0.547 0.453 0.000
I74.5 Embolism and thrombosis of iliac artery
0.545 0.455 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.545 0.455 0.000
E83.3 Disorders of phosphorus metabolism
0.545 0.455 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.544 0.456 0.000
E55 Vitamin D deficiency
0.544 0.456 0.000
I22.8 Subsequent myocardial infarction of other sites
0.542 0.458 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.542 0.458 0.000
I35.8 Other aortic valve disorders
0.541 0.459 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.540 0.460 0.000
L89 Decubitus ulcer
0.539 0.461 0.000
N10-N16 Renal tubulo-interstitial diseases
0.538 0.462 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.537 0.463 0.000
S06 Intracranial injury
0.536 0.464 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.534 0.466 0.000
I35.9 Aortic valve disorder, unspecified
0.533 0.466 0.000
I77.8 Other specified disorders of arteries and arterioles
0.533 0.467 0.000
H60-H62 Diseases of external ear
0.533 0.467 0.000
N35.9 Urethral stricture, unspecified
0.533 0.467 0.000
T90 Sequelae of injuries of head
0.529 0.471 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.528 0.472 0.000
I74.8 Embolism and thrombosis of other arteries
0.528 0.472 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.528 0.472 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.528 0.472 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.528 0.472 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.528 0.472 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.527 0.473 0.000
A41.4 Septicaemia due to anaerobes
0.527 0.473 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.527 0.473 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.527 0.473 0.000
T79-T79 Certain early complications of trauma
0.526 0.474 0.000
G91 Hydrocephalus
0.526 0.474 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.526 0.474 0.000
E40-E46 Malnutrition
0.526 0.474 0.000
G35 Multiple sclerosis
0.525 0.475 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.525 0.475 0.000
C90.0 Multiple myeloma
0.524 0.476 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.522 0.478 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.522 0.478 0.000
Q35-Q37 Cleft lip and cleft palate
0.522 0.478 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.522 0.478 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.522 0.478 0.000
Q00-Q07 Congenital malformations of the nervous system
0.522 0.478 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.521 0.479 0.000
I79.1 Aortitis in diseases classified elsewhere
0.521 0.479 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.521 0.479 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.521 0.479 0.000
S92 Fracture of foot, except ankle
0.521 0.479 0.000
L90.0 Lichen sclerosus et atrophicus
0.519 0.481 0.000
I72.8 Aneurysm of other specified arteries
0.519 0.481 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.518 0.482 0.000
I27.9 Pulmonary heart disease, unspecified
0.518 0.482 0.000
I27.8 Other specified pulmonary heart diseases
0.518 0.482 0.000
I27.1 Kyphoscoliotic heart disease
0.518 0.482 0.000
B37.7 Candidal septicaemia
0.518 0.482 0.000
B37.6 Candidal endocarditis
0.518 0.482 0.000
B37.5 Candidal meningitis
0.518 0.482 0.000
B37.4 Candidiasis of other urogenital sites
0.518 0.482 0.000
B37.2 Candidiasis of skin and nail
0.518 0.482 0.000
B37.1 Pulmonary candidiasis
0.518 0.482 0.000
I44.6 Other and unspecified fascicular block
0.518 0.482 0.000
I44.5 Left posterior fascicular block
0.518 0.482 0.000
I44.4 Left anterior fascicular block
0.518 0.482 0.000
I44.3 Other and unspecified atrioventricular block
0.518 0.482 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.518 0.482 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.516 0.484 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.516 0.484 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.516 0.484 0.000
L85.3 Xerosis cutis
0.515 0.485 0.000
L85.2 Keratosis punctata (palmaris et plantaris)
0.515 0.485 0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.515 0.485 0.000
L85.0 Acquired ichthyosis
0.515 0.485 0.000
M40-M43 Deforming dorsopathies
0.515 0.485 0.000
H80-H83 Diseases of inner ear
0.514 0.486 0.000
A49.0 Staphylococcal infection, unspecified
0.514 0.486 0.000
E61 Deficiency of other nutrient elements
0.513 0.486 0.000
M20-M25 Other joint disorders
0.513 0.487 0.000
C92 Myeloid leukaemia
0.513 0.487 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.513 0.487 0.000
E80.4 Gilbert's syndrome
0.513 0.487 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.510 0.490 0.000
T92 Sequelae of injuries of upper limb
0.510 0.490 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.510 0.490 0.000
L84 Corns and callosities
0.509 0.491 0.000
S91 Open wound of ankle and foot
0.508 0.491 0.000
C81 Hodgkin's disease
0.508 0.492 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.508 0.492 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.508 0.492 0.000
I46.9 Cardiac arrest, unspecified
0.506 0.494 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.505 0.495 0.000
E23 Hypofunction and other disorders of pituitary gland
0.505 0.495 0.000
B25-B34 Other viral diseases
0.504 0.495 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.504 0.496 0.000
S00.7 Multiple superficial injuries of head
0.504 0.496 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.504 0.496 0.000
S68 Traumatic amputation of wrist and hand
0.503 0.497 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.503 0.497 0.000
S42 Fracture of shoulder and upper arm
0.502 0.498 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.501 0.499 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.501 0.499 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.501 0.499 0.000
I30.8 Other forms of acute pericarditis
0.500 0.500 0.000
I30.1 Infective pericarditis
0.500 0.500 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.500 0.500 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.500 0.500 0.000
I34 Nonrheumatic mitral valve disorders
0.500 0.500 0.000
A49.3 Mycoplasma infection, unspecified
0.495 0.505 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.495 0.505 0.000
A49.1 Streptococcal infection, unspecified
0.495 0.505 0.000
H71 Cholesteatoma of middle ear
0.495 0.505 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.495 0.505 0.000
N17.8 Other acute renal failure
0.494 0.505 0.000
N17.2 Acute renal failure with medullary necrosis
0.494 0.505 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.494 0.505 0.000
C15 Malignant neoplasm of oesophagus
0.494 0.506 0.000
B99 Other and unspecified infectious diseases
0.493 0.507 0.000
L91.0 Keloid scar
0.493 0.507 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.492 0.508 0.000
E85 Amyloidosis
0.491 0.509 0.000
E84 Cystic fibrosis
0.491 0.509 0.000
E79 Disorders of purine and pyrimidine metabolism
0.491 0.509 0.000
E77 Disorders of glycoprotein metabolism
0.491 0.509 0.000
E76 Disorders of glycosaminoglycan metabolism
0.491 0.509 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.491 0.509 0.000
E74 Other disorders of carbohydrate metabolism
0.491 0.509 0.000
E73 Lactose intolerance
0.491 0.509 0.000
E72 Other disorders of amino-acid metabolism
0.491 0.509 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.491 0.509 0.000
E70 Disorders of aromatic amino-acid metabolism
0.491 0.509 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.491 0.509 0.000
S41 Open wound of shoulder and upper arm
0.490 0.510 0.000
L81 Other disorders of pigmentation
0.489 0.511 0.000
S08 Traumatic amputation of part of head
0.489 0.511 0.000
S07 Crushing injury of head
0.489 0.511 0.000
S05 Injury of eye and orbit
0.489 0.511 0.000
S04 Injury of cranial nerves
0.489 0.511 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.489 0.511 0.000
M70-M79 Other soft tissue disorders
0.489 0.511 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.488 0.511 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.488 0.511 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.488 0.511 0.000
C21 Malignant neoplasm of anus and anal canal
0.488 0.511 0.000
C17 Malignant neoplasm of small intestine
0.488 0.511 0.000
C23 Malignant neoplasm of gallbladder
0.488 0.511 0.000
S64 Injury of nerves at wrist and hand level
0.488 0.512 0.000
N18.1 Chronic kidney disease, stage 1
0.488 0.512 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.487 0.512 0.000
G93.0 Cerebral cysts
0.487 0.513 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.487 0.513 0.000
M00-M03 Infectious arthropathies
0.485 0.515 0.000
G95 Other diseases of spinal cord
0.485 0.515 0.000
I49 Other cardiac arrhythmias
0.485 0.515 0.000
C44 Other malignant neoplasms of skin
0.484 0.516 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.483 0.517 0.000
S01 Open wound of head
0.483 0.517 0.000
I51.6 Cardiovascular disease, unspecified
0.482 0.517 0.000
I51.5 Myocardial degeneration
0.482 0.517 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.482 0.517 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.482 0.517 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.482 0.517 0.000
I51.0 Cardiac septal defect, acquired
0.482 0.517 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.482 0.517 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.482 0.518 0.000
C16 Malignant neoplasm of stomach
0.482 0.518 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.482 0.518 0.000
B37.3 Candidiasis of vulva and vagina
0.481 0.519 0.000
S69 Other and unspecified injuries of wrist and hand
0.481 0.519 0.000
E26 Hyperaldosteronism
0.479 0.521 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.478 0.521 0.000
S09 Other and unspecified injuries of head
0.478 0.522 0.000
E83.4 Disorders of magnesium metabolism
0.477 0.523 0.000
N05 Unspecified nephritic syndrome
0.477 0.523 0.000
I78.9 Disease of capillaries, unspecified
0.477 0.523 0.000
I78.8 Other diseases of capillaries
0.477 0.523 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.477 0.523 0.000
E63 Other nutritional deficiencies
0.477 0.523 0.000
E56 Other vitamin deficiencies
0.477 0.523 0.000
E51 Thiamine deficiency
0.477 0.523 0.000
E50 Vitamin A deficiency
0.477 0.523 0.000
E60 Dietary zinc deficiency
0.477 0.523 0.000
E59 Dietary selenium deficiency
0.477 0.523 0.000
E58 Dietary calcium deficiency
0.477 0.523 0.000
E54 Ascorbic acid deficiency
0.477 0.523 0.000
E52 Niacin deficiency [pellagra]
0.477 0.523 0.000
G96 Other disorders of central nervous system
0.477 0.523 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.477 0.523 0.000
B91 Sequelae of poliomyelitis
0.476 0.524 0.000
I77.6 Arteritis, unspecified
0.476 0.524 0.000
S99 Other and unspecified injuries of ankle and foot
0.475 0.525 0.000
S98 Traumatic amputation of ankle and foot
0.475 0.525 0.000
S97 Crushing injury of ankle and foot
0.475 0.525 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.475 0.525 0.000
S95 Injury of blood vessels at ankle and foot level
0.475 0.525 0.000
S94 Injury of nerves at ankle and foot level
0.475 0.525 0.000
S90 Superficial injury of ankle and foot
0.475 0.525 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.474 0.526 0.000
I23.8 Other current complications following acute myocardial infarction
0.473 0.527 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.473 0.527 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.473 0.527 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.473 0.527 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.473 0.527 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.473 0.527 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.473 0.527 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.473 0.527 0.000
T78.3 Angioneurotic oedema
0.473 0.527 0.000
L91.8 Other hypertrophic disorders of skin
0.472 0.528 0.000
N04 Nephrotic syndrome
0.472 0.528 0.000
N13 Obstructive and reflux uropathy
0.471 0.529 0.000
I02 Rheumatic chorea
0.471 0.529 0.000
I01 Rheumatic fever with heart involvement
0.471 0.529 0.000
I00 Rheumatic fever without mention of heart involvement
0.471 0.529 0.000
S00.1 Contusion of eyelid and periocular area
0.470 0.529 0.000
T93 Sequelae of injuries of lower limb
0.470 0.530 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.470 0.530 0.000
B35.1 Tinea unguium
0.470 0.530 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.470 0.530 0.000
C95 Leukaemia of unspecified cell type
0.470 0.530 0.000
C94 Other leukaemias of specified cell type
0.470 0.530 0.000
C93 Monocytic leukaemia
0.470 0.530 0.000
C88 Malignant immunoproliferative diseases
0.470 0.530 0.000
C86 Other specified types of T/NK-cell lymphoma
0.470 0.530 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.470 0.530 0.000
I78.1 Naevus, nonneoplastic
0.470 0.530 0.000
I72.9 Aneurysm of unspecified site
0.469 0.531 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.469 0.531 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.469 0.531 0.000
I72.3 Aneurysm of iliac artery
0.469 0.531 0.000
I72.2 Aneurysm of renal artery
0.469 0.531 0.000
I72.1 Aneurysm of artery of upper extremity
0.469 0.531 0.000
I72.0 Aneurysm of carotid artery
0.469 0.531 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.469 0.531 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.469 0.531 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.469 0.531 0.000
G90 Disorders of autonomic nervous system
0.469 0.531 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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