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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1539454
log Bayes Factor = 14.3346
Chromosome 1   position 219,983,780  (GRCh37) Explore rs1539454 on Ensembl!
Variant rs1539454 is part of Cluster X0159

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N81 Female genital prolapse
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
N81.1 Cystocele
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
N30-N39 Other diseases of urinary system
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.990 0.010 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.989 0.011 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.987 0.013 0.000
K80 Cholelithiasis
0.985 0.015 0.000
Chapter I Certain infectious and parasitic diseases
0.980 0.020 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.979 0.021 0.000
G40-G47 Episodic and paroxysmal disorders
0.976 0.024 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.973 0.027 0.000
Z93 Artificial opening status
0.973 0.027 0.000
Z96 Presence of other functional implants
0.973 0.027 0.000
N39 Other disorders of urinary system
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.970 0.030 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.965 0.035 0.000
Z96.6 Presence of orthopaedic joint implants
0.965 0.035 0.000
N88 Other noninflammatory disorders of cervix uteri
0.950 0.050 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.950 0.050 0.000
K81 Cholecystitis
0.948 0.052 0.000
G40 Epilepsy
0.945 0.055 0.000
N39.3 Stress incontinence
0.945 0.055 0.000
N60-N64 Disorders of breast
0.941 0.059 0.000
N81.3 Complete uterovaginal prolapse
0.940 0.060 0.000
Z46 Fitting and adjustment of other devices
0.940 0.060 0.000
Z51 Other medical care
0.938 0.062 0.000
N39.4 Other specified urinary incontinence
0.937 0.063 0.000
K50-K52 Noninfective enteritis and colitis
0.927 0.073 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.925 0.075 0.000
Z90.5 Acquired absence of kidney
0.924 0.076 0.000
N81.5 Vaginal enterocele
0.922 0.078 0.000
N30 Cystitis
0.918 0.082 0.000
S00-S09 Injuries to the head
0.918 0.082 0.000
K11 Diseases of salivary glands
0.910 0.090 0.000
N81.6 Rectocele
0.907 0.093 0.000
Z46.6 Fitting and adjustment of urinary device
0.904 0.096 0.000
N10-N16 Renal tubulo-interstitial diseases
0.902 0.098 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.902 0.098 0.000
G40.9 Epilepsy, unspecified
0.901 0.099 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.899 0.101 0.000
K81.9 Cholecystitis, unspecified
0.898 0.102 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.898 0.102 0.000
Chapter II Neoplasms
0.892 0.108 0.000
A00-A09 Intestinal infectious diseases
0.889 0.111 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.889 0.111 0.000
Chapter VIII Diseases of the ear and mastoid process
0.887 0.113 0.000
K82 Other diseases of gallbladder
0.886 0.114 0.000
Z51.5 Palliative care
0.879 0.121 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.877 0.123 0.000
K86 Other diseases of pancreas
0.874 0.126 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.873 0.127 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.873 0.127 0.000
K02 Dental caries
0.865 0.135 0.000
Z90.7 Acquired absence of genital organ(s)
0.862 0.138 0.000
A30-A49 Other bacterial diseases
0.855 0.145 0.000
Z93.1 Gastrostomy status
0.853 0.147 0.000
N32 Other disorders of bladder
0.853 0.147 0.000
N81.4 Uterovaginal prolapse, unspecified
0.851 0.149 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.850 0.150 0.000
S80-S89 Injuries to the knee and lower leg
0.849 0.151 0.000
Z93.3 Colostomy status
0.847 0.153 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.846 0.154 0.000
K05 Gingivitis and periodontal diseases
0.844 0.156 0.000
K35-K38 Diseases of appendix
0.844 0.156 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.841 0.159 0.000
B35-B49 Mycoses
0.841 0.159 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.838 0.162 0.000
S00 Superficial injury of head
0.837 0.163 0.000
Z93.2 Ileostomy status
0.835 0.165 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.834 0.166 0.000
N64 Other disorders of breast
0.834 0.166 0.000
N88.2 Stricture and stenosis of cervix uteri
0.828 0.172 0.000
K83 Other diseases of biliary tract
0.826 0.174 0.000
Z45 Adjustment and management of implanted device
0.826 0.174 0.000
N94.6 Dysmenorrhoea, unspecified
0.824 0.176 0.000
K51 Ulcerative colitis
0.824 0.176 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.822 0.178 0.000
Y86 Sequelae of other accidents
0.820 0.180 0.000
N17-N19 Renal failure
0.816 0.184 0.000
O60-O75 Complications of labour and delivery
0.815 0.185 0.000
Z48 Other surgical follow-up care
0.814 0.186 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.812 0.187 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.811 0.189 0.000
Z80 Family history of malignant neoplasm
0.810 0.190 0.000
K90-K93 Other diseases of the digestive system
0.810 0.190 0.000
Z51.1 Chemotherapy session for neoplasm
0.809 0.191 0.000
Z93.6 Other artificial openings of urinary tract status
0.807 0.193 0.000
B95-B98 Bacterial, viral and other infectious agents
0.807 0.193 0.000
Z89 Acquired absence of limb
0.806 0.194 0.000
W20-W49 Exposure to inanimate mechanical forces
0.802 0.198 0.000
Z43 Attention to artificial openings
0.800 0.200 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.797 0.202 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.797 0.202 0.000
N94.1 Dyspareunia
0.795 0.205 0.000
N63 Unspecified lump in breast
0.794 0.206 0.000
K85 Acute pancreatitis
0.792 0.208 0.000
K11.2 Sialoadenitis
0.791 0.209 0.000
A08 Viral and other specified intestinal infections
0.791 0.209 0.000
N81.8 Other female genital prolapse
0.790 0.210 0.000
G20-G26 Extrapyramidal and movement disorders
0.789 0.211 0.000
Z49 Care involving dialysis
0.788 0.212 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.787 0.213 0.000
S60-S69 Injuries to the wrist and hand
0.786 0.214 0.000
N60 Benign mammary dysplasia
0.784 0.216 0.000
N13 Obstructive and reflux uropathy
0.784 0.216 0.000
C15-C26 Malignant neoplasms of digestive organs
0.783 0.217 0.000
K70-K77 Diseases of liver
0.782 0.218 0.000
N30.0 Acute cystitis
0.782 0.218 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.782 0.218 0.000
K29 Gastritis and duodenitis
0.781 0.219 0.000
Z54 Convalescence
0.780 0.220 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.775 0.225 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.775 0.225 0.000
K29.7 Gastritis, unspecified
0.774 0.226 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.772 0.228 0.000
Z94 Transplanted organ and tissue status
0.770 0.230 0.000
H65-H75 Diseases of middle ear and mastoid
0.768 0.232 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.766 0.234 0.000
Z93.0 Tracheostomy status
0.765 0.235 0.000
N99-N99 Other disorders of the genitourinary system
0.765 0.235 0.000
K50 Crohn's disease [regional enteritis]
0.765 0.235 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.763 0.237 0.000
S40-S49 Injuries to the shoulder and upper arm
0.762 0.238 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.762 0.238 0.000
K82.4 Cholesterolosis of gallbladder
0.762 0.238 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.760 0.240 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.760 0.240 0.000
T82.1 Mechanical complication of cardiac electronic device
0.760 0.240 0.000
N92 Excessive, frequent and irregular menstruation
0.759 0.241 0.000
N80 Endometriosis
0.759 0.241 0.000
V40-V49 Car occupant injured in transport accident
0.759 0.241 0.000
G70-G73 Diseases of myoneural junction and muscle
0.758 0.242 0.000
N73 Other female pelvic inflammatory diseases
0.757 0.243 0.000
K80.8 Other cholelithiasis
0.756 0.244 0.000
N64.5 Other signs and symptoms in breast
0.755 0.245 0.000
N61 Inflammatory disorders of breast
0.755 0.245 0.000
Z51.2 Other chemotherapy
0.753 0.247 0.000
B15-B19 Viral hepatitis
0.753 0.247 0.000
T66-T78 Other and unspecified effects of external causes
0.753 0.247 0.000
K22 Other diseases of oesophagus
0.751 0.249 0.000
G90-G99 Other disorders of the nervous system
0.750 0.249 0.000
T79-T79 Certain early complications of trauma
0.750 0.250 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.750 0.250 0.000
K11.5 Sialolithiasis
0.749 0.251 0.000
Z90.0 Acquired absence of part of head and neck
0.749 0.251 0.000
S90-S99 Injuries to the ankle and foot
0.748 0.252 0.000
K81.0 Acute cholecystitis
0.747 0.253 0.000
M15-M19 Arthrosis
0.747 0.253 0.000
V10-V19 Pedal cyclist injured in transport accident
0.747 0.253 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.744 0.256 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.744 0.256 0.000
K02.9 Dental caries, unspecified
0.743 0.257 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.742 0.258 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.258 0.000
B37 Candidiasis
0.741 0.259 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.741 0.259 0.000
S02 Fracture of skull and facial bones
0.739 0.261 0.000
K11.6 Mucocele of salivary gland
0.738 0.262 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.738 0.262 0.000
Chapter XXII Codes for special purposes
0.736 0.264 0.000
N30.9 Cystitis, unspecified
0.735 0.265 0.000
T90 Sequelae of injuries of head
0.734 0.266 0.000
Z97 Presence of other devices
0.733 0.267 0.000
G44 Other headache syndromes
0.731 0.269 0.000
N32.0 Bladder-neck obstruction
0.731 0.269 0.000
K12 Stomatitis and related lesions
0.730 0.270 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.730 0.270 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.729 0.271 0.000
D00-D09 In situ neoplasms
0.729 0.271 0.000
Z96.8 Presence of other specified functional implants
0.728 0.272 0.000
T93 Sequelae of injuries of lower limb
0.728 0.272 0.000
Z45.2 Adjustment and management of vascular access device
0.728 0.272 0.000
A41 Other septicaemia
0.727 0.273 0.000
C64-C68 Malignant neoplasms of urinary tract
0.727 0.273 0.000
M17 Gonarthrosis [arthrosis of knee]
0.726 0.274 0.000
S00.9 Superficial injury of head, part unspecified
0.726 0.274 0.000
G43 Migraine
0.726 0.274 0.000
Z50 Care involving use of rehabilitation procedures
0.725 0.275 0.000
K13 Other diseases of lip and oral mucosa
0.725 0.275 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.725 0.275 0.000
K05.1 Chronic gingivitis
0.725 0.275 0.000
N30.2 Other chronic cystitis
0.724 0.276 0.000
Z41 Procedures for purposes other than remedying health state
0.723 0.277 0.000
K82.8 Other specified diseases of gallbladder
0.723 0.277 0.000
K86.9 Disease of pancreas, unspecified
0.720 0.280 0.000
A08.4 Viral intestinal infection, unspecified
0.720 0.280 0.000
K35 Acute appendicitis
0.719 0.281 0.000
N70 Salpingitis and oophoritis
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N81.0 Female urethrocele
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.717 0.283 0.000
K08 Other disorders of teeth and supporting structures
0.715 0.285 0.000
N76 Other inflammation of vagina and vulva
0.715 0.285 0.000
Z90.8 Acquired absence of other organs
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.285 0.000
S10-S19 Injuries to the neck
0.714 0.285 0.000
N37 Urethral disorders in diseases classified elsewhere
0.714 0.286 0.000
N34 Urethritis and urethral syndrome
0.714 0.286 0.000
N33 Bladder disorders in diseases classified elsewhere
0.714 0.286 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.714 0.286 0.000
K52 Other non-infective gastro-enteritis and colitis
0.714 0.286 0.000
N36 Other disorders of urethra
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.712 0.288 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.711 0.288 0.000
N71 Inflammatory disease of uterus, except cervix
0.711 0.289 0.000
Z84 Family history of other conditions
0.710 0.290 0.000
Z81 Family history of mental and behavioural disorders
0.710 0.290 0.000
Z52 Donors of organs and tissues
0.709 0.291 0.000
Z44 Fitting and adjustment of external prosthetic device
0.709 0.291 0.000
N13.3 Other and unspecified hydronephrosis
0.708 0.292 0.000
Z51.0 Radiotherapy session
0.708 0.292 0.000
K40-K46 Hernia
0.708 0.292 0.000
X60-X84 Intentional self-harm
0.708 0.292 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.708 0.292 0.000
K80.3 Calculus of bile duct with cholangitis
0.706 0.294 0.000
K80.4 Calculus of bile duct with cholecystitis
0.706 0.294 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.705 0.295 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.704 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.703 0.296 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.703 0.297 0.000
B99-B99 Other infectious diseases
0.703 0.297 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.703 0.297 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.703 0.297 0.000
B65-B83 Helminthiases
0.703 0.297 0.000
B50-B64 Protozoal diseases
0.703 0.297 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.703 0.297 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.703 0.297 0.000
A80-A89 Viral infections of the central nervous system
0.703 0.297 0.000
A75-A79 Rickettsioses
0.703 0.297 0.000
A70-A74 Other diseases caused by chlamydiae
0.703 0.297 0.000
A65-A69 Other spirochaetal diseases
0.703 0.297 0.000
A20-A28 Certain zoonotic bacterial diseases
0.703 0.297 0.000
A15-A19 Tuberculosis
0.703 0.297 0.000
G30-G32 Other degenerative diseases of the nervous system
0.703 0.297 0.000
S50-S59 Injuries to the elbow and forearm
0.703 0.297 0.000
K10 Other diseases of jaws
0.702 0.298 0.000
K09 Cysts of oral region, not elsewhere classified
0.702 0.298 0.000
K07 Dentofacial anomalies [including malocclusion]
0.702 0.298 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.702 0.298 0.000
K03 Other diseases of hard tissues of teeth
0.702 0.298 0.000
K00 Disorders of tooth development and eruption
0.702 0.298 0.000
K01 Embedded and impacted teeth
0.702 0.298 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.702 0.298 0.000
T88.4 Failed or difficult intubation
0.700 0.300 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.700 0.300 0.000
G41 Status epilepticus
0.700 0.300 0.000
K02.8 Other dental caries
0.700 0.300 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.700 0.300 0.000
N30.8 Other cystitis
0.699 0.301 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.699 0.301 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.698 0.302 0.000
H90-H95 Other disorders of ear
0.698 0.302 0.000
Z96.0 Presence of urogenital implants
0.698 0.302 0.000
Z93.9 Artificial opening status, unspecified
0.697 0.303 0.000
Z93.8 Other artificial opening status
0.697 0.303 0.000
Z93.5 Cystostomy status
0.697 0.303 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.697 0.303 0.000
Z96.9 Presence of functional implant, unspecified
0.697 0.303 0.000
Z96.7 Presence of other bone and tendon implants
0.697 0.303 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.697 0.303 0.000
Z96.4 Presence of endocrine implants
0.697 0.303 0.000
Z96.3 Presence of artificial larynx
0.697 0.303 0.000
Z96.2 Presence of otological and audiological implants
0.697 0.303 0.000
N10 Acute tubulo-interstitial nephritis
0.697 0.303 0.000
N39.2 Orthostatic proteinuria, unspecified
0.697 0.303 0.000
N39.1 Persistent proteinuria, unspecified
0.697 0.303 0.000
V20-V29 Motorcycle rider injured in transport accident
0.696 0.304 0.000
N30.3 Trigonitis
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.695 0.305 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.305 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.305 0.000
S09 Other and unspecified injuries of head
0.695 0.305 0.000
M17.1 Other primary gonarthrosis
0.695 0.305 0.000
S06 Intracranial injury
0.694 0.306 0.000
N86 Erosion and ectropion of cervix uteri
0.693 0.307 0.000
N81.9 Female genital prolapse, unspecified
0.692 0.308 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.692 0.308 0.000
N32.3 Diverticulum of bladder
0.691 0.309 0.000
Z45.1 Adjustment and management of infusion pump
0.691 0.309 0.000
K83.9 Disease of biliary tract, unspecified
0.690 0.310 0.000
N18 Chronic renal failure
0.690 0.310 0.000
Z90.3 Acquired absence of part of stomach
0.688 0.312 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.688 0.312 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.687 0.313 0.000
A49 Bacterial infection of unspecified site
0.686 0.314 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.686 0.314 0.000
W29 Contact with other powered hand tools and household machinery
0.686 0.314 0.000
N95 Menopausal and other perimenopausal disorders
0.685 0.315 0.000
K51.9 Ulcerative colitis, unspecified
0.684 0.316 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.683 0.317 0.000
K65-K67 Diseases of peritoneum
0.683 0.317 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.682 0.318 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.681 0.318 0.000
N88.4 Hypertrophic elongation of cervix uteri
0.681 0.318 0.000
N88.3 Incompetence of cervix uteri
0.681 0.318 0.000
N88.1 Old laceration of cervix uteri
0.681 0.318 0.000
N88.0 Leukoplakia of cervix uteri
0.681 0.318 0.000
T87 Complications peculiar to reattachment and amputation
0.681 0.319 0.000
T86 Failure and rejection of transplanted organs and tissues
0.681 0.319 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.681 0.319 0.000
Z80.3 Family history of malignant neoplasm of breast
0.681 0.319 0.000
S00.1 Contusion of eyelid and periocular area
0.680 0.320 0.000
K81.8 Other cholecystitis
0.680 0.320 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.679 0.321 0.000
K81.1 Chronic cholecystitis
0.679 0.321 0.000
Y85 Sequelae of transport accidents
0.678 0.322 0.000
Z47 Other orthopaedic follow-up care
0.678 0.322 0.000
G40.8 Other epilepsy
0.677 0.322 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.677 0.322 0.000
G40.5 Special epileptic syndromes
0.677 0.322 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.677 0.322 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.677 0.322 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.677 0.322 0.000
Z90.2 Acquired absence of lung [part of]
0.676 0.324 0.000
Z98 Other postsurgical states
0.676 0.324 0.000
Z48.8 Other specified surgical follow-up care
0.675 0.325 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.674 0.326 0.000
Z46.8 Fitting and adjustment of other specified devices
0.674 0.326 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.674 0.326 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.674 0.326 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.674 0.326 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.674 0.326 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.674 0.326 0.000
Z46.1 Fitting and adjustment of hearing aid
0.674 0.326 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.674 0.326 0.000
Z89.5 Acquired absence of leg at or below knee
0.673 0.326 0.000
K86.8 Other specified diseases of pancreas
0.673 0.326 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.673 0.327 0.000
Z51.9 Medical care, unspecified
0.672 0.328 0.000
Z51.6 Desensitisation to allergens
0.672 0.328 0.000
K51.4 Pseudopolyposis of colon
0.672 0.328 0.000
Chapter VII Diseases of the eye and adnexa
0.672 0.328 0.000
K85.1 Biliary acute pancreatitis
0.671 0.329 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.671 0.329 0.000
K14 Diseases of tongue
0.670 0.330 0.000
K86.1 Other chronic pancreatitis
0.669 0.331 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.669 0.331 0.000
O72 Postpartum haemorrhage
0.668 0.332 0.000
H71 Cholesteatoma of middle ear
0.664 0.336 0.000
K83.1 Obstruction of bile duct
0.663 0.337 0.000
B25-B34 Other viral diseases
0.663 0.337 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.663 0.337 0.000
N94.5 Secondary dysmenorrhoea
0.663 0.337 0.000
N94.4 Primary dysmenorrhoea
0.663 0.337 0.000
N94.3 Premenstrual tension syndrome
0.663 0.337 0.000
N94.2 Vaginismus
0.663 0.337 0.000
N94.0 Mittelschmerz
0.663 0.337 0.000
N32.8 Other specified disorders of bladder
0.663 0.337 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.663 0.337 0.000
C16 Malignant neoplasm of stomach
0.662 0.338 0.000
S83.2 Tear of meniscus, current
0.662 0.338 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.662 0.338 0.000
K38 Other diseases of appendix
0.661 0.338 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.661 0.339 0.000
B37.8 Candidiasis of other sites
0.661 0.339 0.000
Z51.3 Blood transfusion without reported diagnosis
0.660 0.340 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.659 0.341 0.000
Y40 Systemic antibiotics
0.659 0.341 0.000
N30.4 Irradiation cystitis
0.658 0.341 0.000
S08 Traumatic amputation of part of head
0.658 0.342 0.000
S07 Crushing injury of head
0.658 0.342 0.000
S05 Injury of eye and orbit
0.658 0.342 0.000
S04 Injury of cranial nerves
0.658 0.342 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.658 0.342 0.000
S61 Open wound of wrist and hand
0.657 0.343 0.000
G57 Mononeuropathies of lower limb
0.657 0.343 0.000
K22.7 Barrett's oesophagus
0.656 0.344 0.000
K86.3 Pseudocyst of pancreas
0.656 0.344 0.000
W00-W19 Falls
0.655 0.345 0.000
N60.3 Fibrosclerosis of breast
0.655 0.345 0.000
H80-H83 Diseases of inner ear
0.654 0.346 0.000
K22.1 Ulcer of oesophagus
0.654 0.346 0.000
S70-S79 Injuries to the hip and thigh
0.654 0.346 0.000
S00.8 Superficial injury of other parts of head
0.653 0.347 0.000
O70 Perineal laceration during delivery
0.653 0.347 0.000
N73.6 Female pelvic peritoneal adhesions
0.653 0.347 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.653 0.347 0.000
K11.9 Disease of salivary gland, unspecified
0.652 0.347 0.000
K11.8 Other diseases of salivary glands
0.652 0.347 0.000
K11.7 Disturbances of salivary secretion
0.652 0.347 0.000
K11.4 Fistula of salivary gland
0.652 0.347 0.000
K11.3 Abscess of salivary gland
0.652 0.347 0.000
K11.1 Hypertrophy of salivary gland
0.652 0.347 0.000
K11.0 Atrophy of salivary gland
0.652 0.347 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.652 0.348 0.000
K05.3 Chronic periodontitis
0.652 0.348 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.650 0.350 0.000
N60.0 Solitary cyst of breast
0.650 0.350 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.649 0.351 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.647 0.353 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.646 0.353 0.000
N15 Other renal tubulo-interstitial diseases
0.646 0.353 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.646 0.353 0.000
N11 Chronic tubulo-interstitial nephritis
0.646 0.353 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.646 0.353 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.646 0.354 0.000
S20-S29 Injuries to the thorax
0.645 0.355 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.645 0.355 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.645 0.355 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.644 0.355 0.000
G45.3 Amaurosis fugax
0.644 0.355 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.644 0.355 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.644 0.355 0.000
G45.0 Vertebro-basilar artery syndrome
0.644 0.355 0.000
Z49.1 Extracorporeal dialysis
0.644 0.356 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.644 0.356 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.644 0.356 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.644 0.356 0.000
T82.3 Mechanical complication of other vascular grafts
0.644 0.356 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.644 0.356 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.644 0.356 0.000
N89 Other noninflammatory disorders of vagina
0.644 0.356 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.643 0.357 0.000
N72 Inflammatory disease of cervix uteri
0.643 0.357 0.000
K04 Diseases of pulp and periapical tissues
0.641 0.359 0.000
Z22 Carrier of infectious disease
0.641 0.359 0.000
S80 Superficial injury of lower leg
0.640 0.360 0.000
K25 Gastric ulcer
0.640 0.360 0.000
G51 Facial nerve disorders
0.640 0.360 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.640 0.360 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.640 0.360 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.640 0.360 0.000
Z94.8 Other transplanted organ and tissue status
0.640 0.360 0.000
H60-H62 Diseases of external ear
0.639 0.361 0.000
O63 Long labour
0.639 0.361 0.000
N30.1 Interstitial cystitis (chronic)
0.639 0.361 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.638 0.362 0.000
A07 Other protozoal intestinal diseases
0.638 0.362 0.000
A06 Amoebiasis
0.638 0.362 0.000
A05 Other bacterial foodborne intoxications
0.638 0.362 0.000
A03 Shigellosis
0.638 0.362 0.000
A02 Other Salmonella infections
0.638 0.362 0.000
A01 Typhoid and paratyphoid fevers
0.638 0.362 0.000
A00 Cholera
0.638 0.362 0.000
Y89 Sequelae of other external causes
0.637 0.362 0.000
Y88 Sequelae of surgical and medical care as external cause
0.637 0.362 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.637 0.362 0.000
Chapter V Mental and behavioural disorders
0.637 0.363 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.636 0.364 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.636 0.364 0.000
Z42 Follow-up care involving plastic surgery
0.636 0.364 0.000
K82.9 Disease of gallbladder, unspecified
0.635 0.364 0.000
K82.3 Fistula of gallbladder
0.635 0.364 0.000
K82.2 Perforation of gallbladder
0.635 0.364 0.000
K82.1 Hydrops of gallbladder
0.635 0.364 0.000
K82.0 Obstruction of gallbladder
0.635 0.364 0.000
S81 Open wound of lower leg
0.635 0.365 0.000
K50.9 Crohn's disease, unspecified
0.634 0.366 0.000
D45 Polycythaemia vera
0.634 0.366 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.634 0.366 0.000
O62 Abnormalities of forces of labour
0.633 0.367 0.000
M91-M94 Chondropathies
0.633 0.367 0.000
K86.2 Cyst of pancreas
0.630 0.370 0.000
Z54.0 Convalescence following surgery
0.630 0.370 0.000
N92.4 Excessive bleeding in the premenopausal period
0.630 0.370 0.000
Z43.1 Attention to gastrostomy
0.630 0.370 0.000
M86-M90 Other osteopathies
0.630 0.370 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.629 0.371 0.000
T98 Sequelae of other and unspecified effects of external causes
0.629 0.371 0.000
T95 Sequelae of burns, corrosions and frostbite
0.629 0.371 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.629 0.371 0.000
T92 Sequelae of injuries of upper limb
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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