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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17406405
log Bayes Factor = 16.4915
Chromosome 7   position 78,658,711  (GRCh37) Explore rs17406405 on Ensembl!
Variant rs17406405 is part of Cluster X0259

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
0.999 0.001 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
N39 Other disorders of urinary system
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
M23 Internal derangement of knee
0.991 0.009 0.000
N39.0 Urinary tract infection, site not specified
0.991 0.009 0.000
I30-I52 Other forms of heart disease
0.988 0.012 0.000
H53-H54 Visual disturbances and blindness
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.983 0.017 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.982 0.018 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.981 0.019 0.000
H53 Visual disturbances
0.981 0.019 0.000
M25 Other joint disorders, not elsewhere classified
0.971 0.029 0.000
N40-N51 Diseases of male genital organs
0.969 0.031 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.968 0.032 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.954 0.046 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.952 0.048 0.000
I60-I69 Cerebrovascular diseases
0.948 0.052 0.000
M25.5 Pain in joint
0.943 0.057 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.943 0.057 0.000
M05-M14 Inflammatory polyarthropathies
0.941 0.059 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.941 0.059 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.941 0.059 0.000
M25.56 Pain in joint (Lower leg)
0.931 0.069 0.000
Chapter II Neoplasms
0.931 0.069 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.926 0.074 0.000
I05-I09 Chronic rheumatic heart diseases
0.924 0.076 0.000
W00-W19 Falls
0.924 0.076 0.000
N41 Inflammatory diseases of prostate
0.922 0.078 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.917 0.083 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.915 0.085 0.000
S80-S89 Injuries to the knee and lower leg
0.912 0.088 0.000
I10-I15 Hypertensive diseases
0.910 0.090 0.000
N30 Cystitis
0.907 0.093 0.000
G40-G47 Episodic and paroxysmal disorders
0.904 0.096 0.000
I73 Other peripheral vascular diseases
0.904 0.096 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.900 0.100 0.000
G90-G99 Other disorders of the nervous system
0.899 0.101 0.000
C15-C26 Malignant neoplasms of digestive organs
0.899 0.101 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.898 0.102 0.000
I51 Complications and ill-defined descriptions of heart disease
0.897 0.103 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.894 0.106 0.000
Y86 Sequelae of other accidents
0.893 0.107 0.000
O00-O08 Pregnancy with abortive outcome
0.893 0.107 0.000
N42 Other disorders of prostate
0.891 0.109 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.891 0.109 0.000
O60-O75 Complications of labour and delivery
0.889 0.111 0.000
M35 Other systemic involvement of connective tissue
0.883 0.117 0.000
N39.9 Disorder of urinary system, unspecified
0.882 0.118 0.000
M23.3 Other meniscus derangements
0.880 0.120 0.000
M23.8 Other internal derangements of knee
0.878 0.122 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.877 0.123 0.000
W19 Unspecified fall
0.876 0.124 0.000
H53.2 Diplopia
0.876 0.124 0.000
H53.0 Amblyopia ex anopsia
0.874 0.126 0.000
N36 Other disorders of urethra
0.872 0.128 0.000
N41.1 Chronic prostatitis
0.867 0.133 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.866 0.134 0.000
T42.4 Benzodiazepines
0.865 0.135 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.862 0.138 0.000
I12 Hypertensive renal disease
0.860 0.140 0.000
N32 Other disorders of bladder
0.860 0.140 0.000
I71 Aortic aneurysm and dissection
0.859 0.141 0.000
N99-N99 Other disorders of the genitourinary system
0.859 0.141 0.000
M65-M68 Disorders of synovium and tendon
0.855 0.145 0.000
T93 Sequelae of injuries of lower limb
0.855 0.145 0.000
N00-N08 Glomerular diseases
0.854 0.146 0.000
I69 Sequelae of cerebrovascular disease
0.852 0.148 0.000
F41 Other anxiety disorders
0.852 0.148 0.000
H53.1 Subjective visual disturbances
0.852 0.148 0.000
N10-N16 Renal tubulo-interstitial diseases
0.850 0.150 0.000
M05 Seropositive rheumatoid arthritis
0.850 0.150 0.000
N39.8 Other specified disorders of urinary system
0.850 0.150 0.000
N25-N29 Other disorders of kidney and ureter
0.846 0.154 0.000
M25.4 Effusion of joint
0.846 0.154 0.000
I51.7 Cardiomegaly
0.845 0.155 0.000
M21 Other acquired deformities of limbs
0.845 0.155 0.000
Chapter I Certain infectious and parasitic diseases
0.843 0.157 0.000
M11 Other crystal arthropathies
0.838 0.162 0.000
G91 Hydrocephalus
0.837 0.163 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.837 0.163 0.000
I08 Multiple valve diseases
0.836 0.164 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.836 0.164 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.836 0.164 0.000
I78 Diseases of capillaries
0.835 0.165 0.000
I45 Other conduction disorders
0.833 0.167 0.000
M35.3 Polymyalgia rheumatica
0.832 0.168 0.000
F01 Vascular dementia
0.831 0.169 0.000
H10-H13 Disorders of conjunctiva
0.830 0.170 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.830 0.170 0.000
M25.50 Pain in joint (Multiple sites)
0.830 0.170 0.000
W19.2 School, other institution and public administrative area
0.829 0.171 0.000
G70-G73 Diseases of myoneural junction and muscle
0.828 0.172 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.828 0.172 0.000
H02 Other disorders of eyelid
0.826 0.174 0.000
G20-G26 Extrapyramidal and movement disorders
0.824 0.176 0.000
I60 Subarachnoid haemorrhage
0.822 0.178 0.000
N30.9 Cystitis, unspecified
0.822 0.178 0.000
H53.9 Visual disturbance, unspecified
0.819 0.181 0.000
I49 Other cardiac arrhythmias
0.818 0.182 0.000
N32.8 Other specified disorders of bladder
0.818 0.182 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.815 0.185 0.000
N42.8 Other specified disorders of prostate
0.815 0.185 0.000
Chapter VIII Diseases of the ear and mastoid process
0.814 0.186 0.000
F03 Unspecified dementia
0.814 0.186 0.000
F40 Phobic anxiety disorders
0.813 0.187 0.000
H53.8 Other visual disturbances
0.813 0.187 0.000
I38 Endocarditis, valve unspecified
0.813 0.187 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.812 0.188 0.000
H53.4 Visual field defects
0.811 0.189 0.000
I67 Other cerebrovascular diseases
0.810 0.189 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.808 0.192 0.000
I35 Nonrheumatic aortic valve disorders
0.807 0.193 0.000
H04 Disorders of lachrymal system
0.807 0.193 0.000
O02 Other abnormal products of conception
0.806 0.194 0.000
M24 Other specific joint derangements
0.803 0.197 0.000
M70-M79 Other soft tissue disorders
0.803 0.197 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.801 0.199 0.000
N41.0 Acute prostatitis
0.800 0.200 0.000
I44 Atrioventricular and left bundle-branch block
0.796 0.204 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.794 0.206 0.000
M23.5 Chronic instability of knee
0.793 0.207 0.000
N48 Other disorders of penis
0.793 0.207 0.000
N36.8 Other specified disorders of urethra
0.792 0.208 0.000
H55-H59 Other disorders of eye and adnexa
0.792 0.208 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.791 0.209 0.000
I31 Other diseases of pericardium
0.791 0.209 0.000
Y40 Systemic antibiotics
0.789 0.211 0.000
I12.0 Hypertensive renal disease with renal failure
0.788 0.212 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.786 0.214 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.785 0.215 0.000
O03 Spontaneous abortion
0.785 0.215 0.000
S50-S59 Injuries to the elbow and forearm
0.783 0.217 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.783 0.217 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.781 0.219 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.779 0.221 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.775 0.225 0.000
S83.2 Tear of meniscus, current
0.775 0.225 0.000
S20-S29 Injuries to the thorax
0.774 0.226 0.000
S40-S49 Injuries to the shoulder and upper arm
0.774 0.226 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.773 0.227 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.772 0.228 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.772 0.228 0.000
M80-M85 Disorders of bone density and structure
0.771 0.229 0.000
M25.46 Effusion of joint (Lower leg)
0.771 0.229 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.769 0.231 0.000
W50-W64 Exposure to animate mechanical forces
0.768 0.232 0.000
B95-B98 Bacterial, viral and other infectious agents
0.768 0.232 0.000
S10-S19 Injuries to the neck
0.765 0.235 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.765 0.235 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.765 0.235 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.765 0.235 0.000
M11.2 Other chondrocalcinosis
0.764 0.236 0.000
I73.9 Peripheral vascular disease, unspecified
0.763 0.237 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.763 0.237 0.000
V10-V19 Pedal cyclist injured in transport accident
0.762 0.238 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.762 0.238 0.000
M40-M43 Deforming dorsopathies
0.762 0.238 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.761 0.239 0.000
O80-O84 Delivery
0.760 0.240 0.000
Chapter XXII Codes for special purposes
0.759 0.241 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.758 0.242 0.000
H54 Blindness and low vision
0.758 0.242 0.000
Y45.0 Opioids and related analgesics
0.757 0.243 0.000
I50 Heart failure
0.757 0.243 0.000
G91.9 Hydrocephalus, unspecified
0.757 0.243 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.757 0.243 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.757 0.243 0.000
T66-T78 Other and unspecified effects of external causes
0.755 0.245 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.755 0.245 0.000
S90-S99 Injuries to the ankle and foot
0.755 0.245 0.000
I42 Cardiomyopathy
0.755 0.245 0.000
S70-S79 Injuries to the hip and thigh
0.753 0.246 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.753 0.247 0.000
O63 Long labour
0.753 0.247 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.752 0.248 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.752 0.248 0.000
M06 Other rheumatoid arthritis
0.752 0.248 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.752 0.248 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.751 0.249 0.000
I72 Other aneurysm
0.749 0.251 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.749 0.251 0.000
C15 Malignant neoplasm of oesophagus
0.748 0.251 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.748 0.252 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.748 0.252 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.747 0.253 0.000
I73.0 Raynaud's syndrome
0.747 0.253 0.000
M65 Synovitis and tenosynovitis
0.745 0.255 0.000
F01.9 Vascular dementia, unspecified
0.745 0.255 0.000
C64-C68 Malignant neoplasms of urinary tract
0.745 0.255 0.000
M45-M49 Spondylopathies
0.743 0.257 0.000
I12.9 Hypertensive renal disease without renal failure
0.742 0.258 0.000
I46 Cardiac arrest
0.742 0.258 0.000
I73.8 Other specified peripheral vascular diseases
0.742 0.258 0.000
T92 Sequelae of injuries of upper limb
0.742 0.258 0.000
F60-F69 Disorders of adult personality and behaviour
0.741 0.259 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.740 0.260 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.739 0.261 0.000
O02.1 Missed abortion
0.738 0.262 0.000
I51.9 Heart disease, unspecified
0.738 0.262 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.737 0.263 0.000
I77 Other disorders of arteries and arterioles
0.736 0.264 0.000
Y52 Agents primarily affecting the cardiovascular system
0.736 0.264 0.000
I07 Rheumatic tricuspid valve diseases
0.735 0.265 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.734 0.266 0.000
T90 Sequelae of injuries of head
0.734 0.266 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.734 0.266 0.000
F40.2 Specific (isolated) phobias
0.733 0.267 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.733 0.267 0.000
I78.1 Naevus, nonneoplastic
0.731 0.269 0.000
V80-V89 Other land transport accidents
0.731 0.269 0.000
M25.3 Other instability of joint
0.730 0.269 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.730 0.270 0.000
N02 Recurrent and persistent haematuria
0.730 0.270 0.000
Y45.1 Salicylates
0.729 0.271 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.728 0.272 0.000
I35.1 Aortic (valve) insufficiency
0.728 0.272 0.000
M10 Gout
0.727 0.273 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.727 0.273 0.000
Y85 Sequelae of transport accidents
0.726 0.274 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.726 0.274 0.000
I70 Atherosclerosis
0.726 0.274 0.000
O73 Retained placenta and membranes, without haemorrhage
0.722 0.278 0.000
W19.4 Street and highway
0.721 0.279 0.000
F00 Dementia in Alzheimer's disease
0.721 0.279 0.000
E00-E07 Disorders of thyroid gland
0.721 0.279 0.000
S86 Injury of muscle and tendon at lower leg level
0.720 0.279 0.000
X60-X84 Intentional self-harm
0.720 0.280 0.000
H65-H75 Diseases of middle ear and mastoid
0.720 0.280 0.000
N35 Urethral stricture
0.719 0.281 0.000
G30-G32 Other degenerative diseases of the nervous system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
N30.8 Other cystitis
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.717 0.283 0.000
N34 Urethritis and urethral syndrome
0.717 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
C44 Other malignant neoplasms of skin
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.716 0.284 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.715 0.285 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.715 0.285 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.715 0.285 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
N39.2 Orthostatic proteinuria, unspecified
0.714 0.286 0.000
N39.1 Persistent proteinuria, unspecified
0.714 0.286 0.000
F41.9 Anxiety disorder, unspecified
0.714 0.286 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.714 0.286 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.713 0.287 0.000
H20 Iridocyclitis
0.712 0.288 0.000
N42.0 Calculus of prostate
0.712 0.288 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.711 0.289 0.000
M23.9 Internal derangement of knee, unspecified
0.710 0.289 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.710 0.289 0.000
M23.1 Discoid meniscus (congenital)
0.710 0.289 0.000
M23.0 Cystic meniscus
0.710 0.289 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.709 0.291 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.709 0.291 0.000
M23.4 Loose body in knee
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
M15-M19 Arthrosis
0.707 0.293 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.294 0.000
F80-F89 Disorders of psychological development
0.706 0.294 0.000
F70-F79 Mental retardation
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.295 0.000
O85-O92 Complications predominantly related to the puerperium
0.704 0.296 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.704 0.296 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.704 0.296 0.000
G91.1 Obstructive hydrocephalus
0.704 0.296 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.703 0.297 0.000
N17-N19 Renal failure
0.703 0.297 0.000
H53.6 Night blindness
0.703 0.297 0.000
H53.5 Colour vision deficiencies
0.703 0.297 0.000
H53.3 Other disorders of binocular vision
0.703 0.297 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.703 0.297 0.000
I05 Rheumatic mitral valve diseases
0.703 0.297 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.701 0.299 0.000
I11 Hypertensive heart disease
0.701 0.299 0.000
B35-B49 Mycoses
0.700 0.300 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.699 0.301 0.000
T79-T79 Certain early complications of trauma
0.699 0.301 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.698 0.302 0.000
H04.2 Epiphora
0.698 0.302 0.000
M21.2 Flexion deformity
0.698 0.302 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.697 0.303 0.000
O62 Abnormalities of forces of labour
0.697 0.303 0.000
G81 Hemiplegia
0.697 0.303 0.000
M25.9 Joint disorder, unspecified
0.696 0.304 0.000
M25.2 Flail joint
0.696 0.304 0.000
M25.1 Fistula of joint
0.696 0.304 0.000
M25.0 Haemarthrosis
0.696 0.304 0.000
N13 Obstructive and reflux uropathy
0.695 0.305 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.695 0.305 0.000
N46 Male infertility
0.695 0.305 0.000
N44 Torsion of testis
0.695 0.305 0.000
S00-S09 Injuries to the head
0.695 0.305 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.694 0.306 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.694 0.306 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.694 0.306 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.694 0.306 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.694 0.306 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.694 0.306 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.694 0.306 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.694 0.306 0.000
T36 Poisoning by systemic antibiotics
0.694 0.306 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.694 0.306 0.000
I62 Other nontraumatic intracranial haemorrhage
0.694 0.306 0.000
T93.0 Sequelae of open wound of lower limb
0.693 0.307 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.692 0.307 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.692 0.308 0.000
G93 Other disorders of brain
0.690 0.310 0.000
M25.8 Other specified joint disorders
0.690 0.310 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.690 0.310 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.689 0.311 0.000
G25 Other extrapyramidal and movement disorders
0.689 0.311 0.000
T43.2 Other and unspecified antidepressants
0.689 0.311 0.000
A80-A89 Viral infections of the central nervous system
0.687 0.313 0.000
I47 Paroxysmal tachycardia
0.687 0.313 0.000
I44.0 Atrioventricular block, first degree
0.686 0.314 0.000
W13 Fall from, out of or through building or structure
0.686 0.314 0.000
I45.6 Preexcitation syndrome
0.686 0.314 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.685 0.315 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.685 0.315 0.000
H10 Conjunctivitis
0.685 0.315 0.000
Y59 Other and unspecified vaccines and biological substances
0.684 0.316 0.000
Y58 Bacterial vaccines
0.684 0.316 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.684 0.316 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.684 0.316 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.684 0.316 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.684 0.316 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.684 0.316 0.000
Y48 Anaesthetics and therapeutic gases
0.684 0.316 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.684 0.316 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.684 0.316 0.000
Y44 Agents primarily affecting blood constituents
0.684 0.316 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.684 0.316 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.684 0.316 0.000
C44.5 Skin of trunk
0.683 0.317 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.683 0.317 0.000
F02 Dementia in other diseases classified elsewhere
0.683 0.317 0.000
F09 Unspecified organic or symptomatic mental disorder
0.683 0.317 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.683 0.317 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.317 0.000
H16 Keratitis
0.682 0.318 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.681 0.319 0.000
M86-M90 Other osteopathies
0.680 0.320 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.680 0.320 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.680 0.320 0.000
F42 Obsessive-compulsive disorder
0.678 0.322 0.000
H04.1 Other disorders of lachrymal gland
0.677 0.323 0.000
C25 Malignant neoplasm of pancreas
0.677 0.323 0.000
M25.59 Pain in joint (Site unspecified)
0.676 0.324 0.000
M25.58 Pain in joint (Other)
0.676 0.324 0.000
M25.53 Pain in joint (Forearm)
0.676 0.324 0.000
M25.52 Pain in joint (Upper arm)
0.676 0.324 0.000
T98 Sequelae of other and unspecified effects of external causes
0.676 0.324 0.000
T95 Sequelae of burns, corrosions and frostbite
0.676 0.324 0.000
T91 Sequelae of injuries of neck and trunk
0.676 0.324 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.676 0.324 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.676 0.324 0.000
N30.3 Trigonitis
0.675 0.325 0.000
W20-W49 Exposure to inanimate mechanical forces
0.675 0.325 0.000
C16 Malignant neoplasm of stomach
0.675 0.325 0.000
M14 Arthropathies in other diseases classified elsewhere
0.675 0.325 0.000
M12 Other specific arthropathies
0.675 0.325 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.675 0.325 0.000
M08 Juvenile arthritis
0.675 0.325 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.675 0.325 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.675 0.325 0.000
Y89 Sequelae of other external causes
0.674 0.325 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.674 0.325 0.000
T51 Toxic effect of alcohol
0.674 0.326 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.674 0.326 0.000
H02.9 Disorder of eyelid, unspecified
0.674 0.326 0.000
G72 Other myopathies
0.673 0.327 0.000
T93.2 Sequelae of other fractures of lower limb
0.673 0.327 0.000
Y40.9 Systemic antibiotic, unspecified
0.671 0.329 0.000
H01 Other inflammation of eyelid
0.670 0.330 0.000
C21 Malignant neoplasm of anus and anal canal
0.670 0.330 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.669 0.331 0.000
O20 Haemorrhage in early pregnancy
0.669 0.331 0.000
H02.5 Other disorders affecting eyelid function
0.669 0.331 0.000
I50.0 Congestive heart failure
0.669 0.331 0.000
O63.1 Prolonged second stage (of labour)
0.668 0.332 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.668 0.332 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.668 0.332 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.668 0.332 0.000
Y57 Other and unspecified drugs and medicaments
0.668 0.332 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.667 0.333 0.000
F05.9 Delirium, unspecified
0.667 0.333 0.000
T63 Toxic effect of contact with venomous animals
0.667 0.333 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.666 0.334 0.000
W10 Fall on and from stairs and steps
0.665 0.335 0.000
D37.1 Stomach
0.665 0.335 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.664 0.336 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.664 0.336 0.000
F48 Other neurotic disorders
0.664 0.336 0.000
F44 Dissociative [conversion] disorders
0.664 0.336 0.000
W19.3 Sports and athletics area
0.663 0.337 0.000
I49.3 Ventricular premature depolarisation
0.663 0.337 0.000
I09 Other rheumatic heart diseases
0.663 0.337 0.000
I06 Rheumatic aortic valve diseases
0.663 0.337 0.000
W18 Other fall on same level
0.663 0.337 0.000
W17 Other fall from one level to another
0.663 0.337 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.663 0.337 0.000
W15 Fall from cliff
0.663 0.337 0.000
W14 Fall from tree
0.663 0.337 0.000
W12 Fall on and from scaffolding
0.663 0.337 0.000
W11 Fall on and from ladder
0.663 0.337 0.000
W09 Fall involving playground equipment
0.663 0.337 0.000
W08 Fall involving other furniture
0.663 0.337 0.000
W06 Fall involving bed
0.663 0.337 0.000
W05 Fall involving wheelchair
0.663 0.337 0.000
W04 Fall while being carried or supported by other persons
0.663 0.337 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.663 0.337 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.663 0.337 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.663 0.337 0.000
W00 Fall on same level involving ice and snow
0.663 0.337 0.000
I74 Arterial embolism and thrombosis
0.662 0.338 0.000
N32.9 Bladder disorder, unspecified
0.662 0.338 0.000
G40 Epilepsy
0.662 0.338 0.000
S81 Open wound of lower leg
0.661 0.339 0.000
G71 Primary disorders of muscles
0.661 0.339 0.000
N11 Chronic tubulo-interstitial nephritis
0.661 0.339 0.000
N41.8 Other inflammatory diseases of prostate
0.661 0.339 0.000
N41.3 Prostatocystitis
0.661 0.339 0.000
N41.2 Abscess of prostate
0.661 0.339 0.000
M79.8 Other specified soft tissue disorders
0.661 0.339 0.000
I31.3 Pericardial effusion (noninflammatory)
0.660 0.340 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.659 0.340 0.000
Y88 Sequelae of surgical and medical care as external cause
0.659 0.341 0.000
E05.9 Thyrotoxicosis, unspecified
0.659 0.341 0.000
N28.8 Other specified disorders of kidney and ureter
0.658 0.342 0.000
O03.9 Complete or unspecified, without complication
0.658 0.342 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.658 0.342 0.000
G82 Paraplegia and tetraplegia
0.658 0.342 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.657 0.342 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.657 0.342 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.657 0.342 0.000
T42.3 Barbiturates
0.657 0.342 0.000
T42.2 Succinimides and oxazolidinediones
0.657 0.342 0.000
T42.1 Iminostilbenes
0.657 0.342 0.000
T42.0 Hydantoin derivatives
0.657 0.342 0.000
N45 Orchitis and epididymitis
0.657 0.342 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.657 0.342 0.000
N30.1 Interstitial cystitis (chronic)
0.656 0.343 0.000
H18 Other disorders of cornea
0.656 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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