TreeWAS – Variant ID: rs174536

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	1.000	0.000	0.000
J45.9 Asthma, unspecified	0.000	0.211	0.789
J33.0 Polyp of nasal cavity	0.000	0.262	0.738
J33 Nasal polyp	0.000	0.265	0.735
J33.9 Nasal polyp, unspecified	0.000	0.272	0.728
J33.8 Other polyp of sinus	0.000	0.289	0.711
K80 Cholelithiasis	0.690	0.310	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.629	0.371	0.000
K80.4 Calculus of bile duct with cholecystitis	0.571	0.429	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.556	0.444	0.000
J33.1 Polypoid sinus degeneration	0.000	0.467	0.533
K80.3 Calculus of bile duct with cholangitis	0.494	0.505	0.000
K80.8 Other cholelithiasis	0.397	0.603	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.355	0.645	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.313	0.687	0.000
H00.1 Chalazion	0.000	0.737	0.263
E03.9 Hypothyroidism, unspecified	0.000	0.801	0.199
J45 Asthma	0.000	0.843	0.157
H00 Hordeolum and chalazion	0.000	0.876	0.124
J45.8 Mixed asthma	0.000	0.887	0.113
J45.1 Nonallergic asthma	0.000	0.888	0.112
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.097	0.903	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.906	0.093
K83 Other diseases of biliary tract	0.089	0.911	0.000
D25.9 Leiomyoma of uterus, unspecified	0.089	0.911	0.000
E03 Other hypothyroidism	0.000	0.917	0.083
K63.5 Polyp of colon	0.000	0.918	0.082
K83.1 Obstruction of bile duct	0.082	0.918	0.000
K83.0 Cholangitis	0.082	0.918	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.070	0.930	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.934	0.066
N83.2 Other and unspecified ovarian cysts	0.066	0.934	0.000
K83.5 Biliary cyst	0.064	0.936	0.000
K83.2 Perforation of bile duct	0.064	0.936	0.000
K83.4 Spasm of sphincter of Oddi	0.063	0.936	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.938	0.062
E03.5 Myxoedema coma	0.000	0.940	0.060
E03.4 Atrophy of thyroid (acquired)	0.000	0.940	0.060
E03.3 Postinfectious hypothyroidism	0.000	0.940	0.060
E03.1 Congenital hypothyroidism without goitre	0.000	0.940	0.060
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.057	0.943	0.000
K83.3 Fistula of bile duct	0.057	0.943	0.000
E03.8 Other specified hypothyroidism	0.000	0.943	0.057
K83.8 Other specified diseases of biliary tract	0.057	0.943	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.944	0.056
K83.9 Disease of biliary tract, unspecified	0.055	0.945	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.055	0.945	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.053	0.947	0.000
K81 Cholecystitis	0.052	0.948	0.000
K85 Acute pancreatitis	0.051	0.949	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.050	0.950	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.050	0.950	0.000
K76.9 Liver disease, unspecified	0.000	0.950	0.050
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.049	0.951	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.046	0.954	0.000
N83.7 Haematoma of broad ligament	0.041	0.959	0.000
K81.0 Acute cholecystitis	0.041	0.959	0.000
K85.2 Alcohol-induced acute pancreatitis	0.040	0.960	0.000
K85.0 Idiopathic acute pancreatitis	0.039	0.961	0.000
N83.1 Corpus luteum cyst	0.038	0.962	0.000
K85.3 Drug-induced acute pancreatitis	0.037	0.963	0.000
K81.8 Other cholecystitis	0.037	0.963	0.000
N83.6 Haematosalpinx	0.036	0.963	0.000
K85.8 Other acute pancreatitis	0.036	0.964	0.000
D25 Leiomyoma of uterus	0.034	0.966	0.000
K82 Other diseases of gallbladder	0.034	0.966	0.000
K86 Other diseases of pancreas	0.033	0.967	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.033	0.967	0.000
K81.1 Chronic cholecystitis	0.032	0.968	0.000
D25.1 Intramural leiomyoma of uterus	0.029	0.971	0.000
J45.0 Predominantly allergic asthma	0.000	0.971	0.029
K85.1 Biliary acute pancreatitis	0.028	0.972	0.000
N83.0 Follicular cyst of ovary	0.028	0.972	0.000
K82.3 Fistula of gallbladder	0.028	0.972	0.000
K82.9 Disease of gallbladder, unspecified	0.027	0.973	0.000
K86.3 Pseudocyst of pancreas	0.027	0.973	0.000
D25.2 Subserosal leiomyoma of uterus	0.027	0.973	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.026	0.974	0.000
T21 Burn and corrosion of trunk	0.025	0.975	0.000
T23 Burn and corrosion of wrist and hand	0.025	0.975	0.000
K86.8 Other specified diseases of pancreas	0.025	0.975	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.025	0.975	0.000
T23.2 Burn of second degree of wrist and hand	0.024	0.976	0.000
T21.3 Burn of third degree of trunk	0.024	0.976	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.023	0.977	0.000
K82.2 Perforation of gallbladder	0.023	0.977	0.000
T21.0 Burn of unspecified degree of trunk	0.023	0.977	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.977	0.023
T20 Burn and corrosion of head and neck	0.022	0.978	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.022	0.978	0.000
K85.9 Acute pancreatitis, unspecified	0.022	0.978	0.000
K81.9 Cholecystitis, unspecified	0.021	0.979	0.000
K82.4 Cholesterolosis of gallbladder	0.021	0.979	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.021	0.979	0.000
T23.3 Burn of third degree of wrist and hand	0.021	0.979	0.000
T23.1 Burn of first degree of wrist and hand	0.020	0.979	0.000
K82.0 Obstruction of gallbladder	0.020	0.980	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.019	0.981	0.000
T21.2 Burn of second degree of trunk	0.019	0.981	0.000
T20.3 Burn of third degree of head and neck	0.019	0.981	0.000
T21.7 Corrosion of third degree of trunk	0.018	0.981	0.000
T21.6 Corrosion of second degree of trunk	0.018	0.981	0.000
T21.5 Corrosion of first degree of trunk	0.018	0.981	0.000
T21.4 Corrosion of unspecified degree of trunk	0.018	0.981	0.000
T21.1 Burn of first degree of trunk	0.018	0.981	0.000
T23.7 Corrosion of third degree of wrist and hand	0.018	0.982	0.000
T23.6 Corrosion of second degree of wrist and hand	0.018	0.982	0.000
T23.5 Corrosion of first degree of wrist and hand	0.018	0.982	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.018	0.982	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.018	0.982	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.018	0.982	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.982	0.018
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.018	0.982	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.018	0.982	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.018	0.982	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.018	0.982	0.000
T20.2 Burn of second degree of head and neck	0.018	0.982	0.000
T20.0 Burn of unspecified degree of head and neck	0.017	0.983	0.000
K86.1 Other chronic pancreatitis	0.017	0.983	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.017	0.983	0.000
T25 Burn and corrosion of ankle and foot	0.016	0.983	0.000
K82.1 Hydrops of gallbladder	0.016	0.983	0.000
T20.1 Burn of first degree of head and neck	0.016	0.984	0.000
T20.7 Corrosion of third degree of head and neck	0.016	0.984	0.000
T20.6 Corrosion of second degree of head and neck	0.016	0.984	0.000
T20.5 Corrosion of first degree of head and neck	0.016	0.984	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.016	0.984	0.000
R01 Cardiac murmurs and other cardiac sounds	0.000	0.984	0.016
J22 Unspecified acute lower respiratory infection	0.000	0.984	0.016
K86.2 Cyst of pancreas	0.015	0.985	0.000
E00-E07 Disorders of thyroid gland	0.000	0.985	0.015
I80 Phlebitis and thrombophlebitis	0.000	0.985	0.015
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.015	0.985	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.985	0.015
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.986	0.014
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.013	0.987	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.013	0.987	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.013	0.987	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.013	0.987	0.000
D12.5 Sigmoid colon	0.000	0.987	0.013
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.013	0.987	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.013	0.987	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.987	0.013
T25.2 Burn of second degree of ankle and foot	0.012	0.987	0.000
K86.9 Disease of pancreas, unspecified	0.012	0.988	0.000
T25.7 Corrosion of third degree of ankle and foot	0.012	0.988	0.000
T25.6 Corrosion of second degree of ankle and foot	0.012	0.988	0.000
T25.5 Corrosion of first degree of ankle and foot	0.012	0.988	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.012	0.988	0.000
T25.1 Burn of first degree of ankle and foot	0.012	0.988	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.988	0.012
R01.2 Other cardiac sounds	0.000	0.988	0.012
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.988	0.012
T25.3 Burn of third degree of ankle and foot	0.012	0.988	0.000
T93 Sequelae of injuries of lower limb	0.000	0.988	0.012
E07 Other disorders of thyroid	0.000	0.988	0.012
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.988	0.012
T93.0 Sequelae of open wound of lower limb	0.000	0.989	0.011
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.011	0.989	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.989	0.011
E00 Congenital iodine-deficiency syndrome	0.000	0.989	0.011
E07.8 Other specified disorders of thyroid	0.000	0.990	0.010
T25.0 Burn of unspecified degree of ankle and foot	0.010	0.990	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.990	0.010
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.010	0.990	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.010	0.990	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.000	0.990	0.010
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.990	0.010
B37.3 Candidiasis of vulva and vagina	0.000	0.990	0.009
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.991	0.009
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.991	0.009
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
D12.2 Ascending colon	0.000	0.991	0.009
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.991	0.009
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.009	0.991	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.009	0.991	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.009	0.991	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.009	0.991	0.000
D12.3 Transverse colon	0.000	0.991	0.009
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.991	0.009
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.991	0.009
E07.1 Dyshormogenetic goitre	0.000	0.991	0.008
E07.0 Hypersecretion of calcitonin	0.000	0.991	0.008
D12.0 Caecum	0.000	0.991	0.009
T40.4 Other synthetic narcotics	0.009	0.991	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.992	0.008
T46 Poisoning by agents primarily affecting the cardiovascular system	0.008	0.992	0.000
E10.4 With neurological complications	0.000	0.992	0.008
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.992	0.008
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.992	0.008
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.992	0.008
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.992	0.008
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.992	0.008
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.992	0.008
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.992	0.008
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.992	0.008
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.992	0.008
T50.8 Diagnostic agents	0.008	0.992	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
E10.1 With ketoacidosis	0.000	0.992	0.008
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.008	0.992	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.992	0.008
D12.7 Rectosigmoid junction	0.000	0.992	0.008
J20-J22 Other acute lower respiratory infections	0.000	0.992	0.008
H05.2 Exophthalmic conditions	0.000	0.992	0.008
T47.1 Other antacids and anti-gastric-secretion drugs	0.008	0.992	0.000
E06 Thyroiditis	0.000	0.992	0.007
T47.2 Stimulant laxatives	0.008	0.992	0.000
T93.1 Sequelae of fracture of femur	0.000	0.992	0.008
H72 Perforation of tympanic membrane	0.008	0.992	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.992	0.008
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.007	0.992	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.992	0.008
H72.0 Central perforation of tympanic membrane	0.008	0.992	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.007	0.993	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.007	0.993	0.000
H05 Disorders of orbit	0.000	0.993	0.007
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.007	0.993	0.000
H72.8 Other perforations of tympanic membrane	0.007	0.993	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.007	0.993	0.000
D12.1 Appendix	0.000	0.993	0.007
E10.3 With ophthalmic complications	0.000	0.993	0.007
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.993	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.993	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.007	0.993	0.000
T44.0 Anticholinesterase agents	0.007	0.993	0.000
H06.2 Dysthyroid exophthalmos	0.000	0.993	0.007
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.993	0.007
T40.1 Heroin	0.007	0.993	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.993	0.007
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.007	0.993	0.000
T47.0 Histamine H(2)-receptor antagonists	0.007	0.993	0.000
H01 Other inflammation of eyelid	0.000	0.993	0.007
T50.1 Loop [high-ceiling] diuretics	0.007	0.993	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.993	0.007
E05.5 Thyroid crisis or storm	0.000	0.993	0.007
E05.4 Thyrotoxicosis factitia	0.000	0.993	0.007
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.993	0.007
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.993	0.007
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.993	0.007
T40.5 Cocaine	0.007	0.993	0.000
T50.7 Analeptics and opioid receptor antagonists	0.007	0.993	0.000
T50.5 Appetite depressants	0.007	0.993	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
T50.0 Mineralocorticoids and their antagonists	0.007	0.993	0.000
E10.2 With renal complications	0.000	0.993	0.007
T39.0 Salicylates	0.007	0.993	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.007	0.993	0.000
T42.3 Barbiturates	0.007	0.993	0.000
T40.6 Other and unspecified narcotics	0.007	0.993	0.000
T47.4 Other laxatives	0.007	0.993	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.007	0.993	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.007	0.993	0.000
E10.8 With unspecified complications	0.000	0.993	0.007
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.007	0.993	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.007	0.993	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.993	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.993	0.000
T47.7 Emetics	0.006	0.993	0.000
T47.6 Antidiarrhoeal drugs	0.006	0.993	0.000
T47.5 Digestants	0.006	0.993	0.000
T47.3 Saline and osmotic laxatives	0.006	0.993	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.006	0.993	0.000
T40.8 Lysergide [LSD]	0.006	0.993	0.000
T40.7 Cannabis (derivatives)	0.006	0.993	0.000
T40.3 Methadone	0.006	0.993	0.000
T40.0 Opium	0.006	0.993	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.993	0.007
D12.9 Anus and anal canal	0.000	0.993	0.007
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.993	0.000
R01.0 Benign and innocent cardiac murmurs	0.000	0.994	0.006
H69 Other disorders of Eustachian tube	0.000	0.994	0.006
E10.5 With peripheral circulatory complications	0.000	0.994	0.006
T36 Poisoning by systemic antibiotics	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.006	0.994	0.000
T50.4 Drugs affecting uric acid metabolism	0.006	0.994	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.994	0.006
I31.3 Pericardial effusion (noninflammatory)	0.000	0.994	0.006
E10.6 With other specified complications	0.000	0.994	0.006
E10.7 With multiple complications	0.000	0.994	0.006
E05.8 Other thyrotoxicosis	0.000	0.994	0.006
E06.3 Autoimmune thyroiditis	0.000	0.994	0.006
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.006	0.994	0.000
T46.7 Peripheral vasodilators	0.006	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
K76 Other diseases of liver	0.000	0.994	0.006
H06.3 Other disorders of orbit in diseases classified elsewhere	0.000	0.994	0.006
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.000	0.994	0.006
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.000	0.994	0.006
H03 Disorders of eyelid in diseases classified elsewhere	0.000	0.994	0.006
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
J20 Acute bronchitis	0.000	0.994	0.006
H01.0 Blepharitis	0.000	0.994	0.006
G45.4 Transient global amnesia	0.006	0.994	0.000
K11.2 Sialoadenitis	0.000	0.994	0.006
T46.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.006	0.994	0.000
T42.2 Succinimides and oxazolidinediones	0.006	0.994	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.994	0.006
T40.2 Other opioids	0.006	0.994	0.000
H72.1 Attic perforation of tympanic membrane	0.006	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
E06.4 Drug-induced thyroiditis	0.000	0.994	0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.994	0.005
E06.0 Acute thyroiditis	0.000	0.994	0.005
J21 Acute bronchiolitis	0.000	0.994	0.006
E06.1 Subacute thyroiditis	0.000	0.994	0.005
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.994	0.006
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.000	0.994	0.006
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.006
R51 Headache	0.006	0.994	0.000
T42.1 Iminostilbenes	0.006	0.994	0.000
H01.9 Inflammation of eyelid, unspecified	0.000	0.994	0.006
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.000	0.994	0.005
H05.3 Deformity of orbit	0.000	0.994	0.005
H05.1 Chronic inflammatory disorders of orbit	0.000	0.994	0.005
E10.0 With coma	0.000	0.994	0.005
H05.4 Enophthalmos	0.000	0.994	0.005
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.005	0.995	0.000
K82.8 Other specified diseases of gallbladder	0.005	0.995	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
K65.8 Other peritonitis	0.005	0.995	0.000
T39.4 Antirheumatics, not elsewhere classified	0.005	0.995	0.000
T39.2 Pyrazolone derivatives	0.005	0.995	0.000
T41.5 Therapeutic gases	0.005	0.995	0.000
T41.4 Anaesthetic, unspecified	0.005	0.995	0.000
T41.3 Local anaesthetics	0.005	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.005	0.995	0.000
T41.1 Intravenous anaesthetics	0.005	0.995	0.000
T41.0 Inhaled anaesthetics	0.005	0.995	0.000
T48.5 Anti-common-cold drugs	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
J20.9 Acute bronchitis, unspecified	0.000	0.995	0.005
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.995	0.000
T48.4 Expectorants	0.005	0.995	0.000
T48.3 Antitussives	0.005	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.005	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.995	0.000
T48.0 Oxytocic drugs	0.005	0.995	0.000
H05.9 Disorder of orbit, unspecified	0.000	0.995	0.005
E06.5 Other chronic thyroiditis	0.001	0.995	0.004
H01.1 Non-infectious dermatoses of eyelid	0.000	0.995	0.005
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
T37.5 Antiviral drugs	0.005	0.995	0.000
T37.4 Anthelminthics	0.005	0.995	0.000
T37.3 Other antiprotozoal drugs	0.005	0.995	0.000
T37.1 Antimycobacterial drugs	0.005	0.995	0.000
T37.0 Sulphonamides	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
H69.0 Patulous Eustachian tube	0.000	0.995	0.005
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.8 Other systemic antibiotics	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.4 Tetracyclines	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
H05.8 Other disorders of orbit	0.000	0.995	0.005
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.995	0.005
K76.5 Hepatic veno-occlusive disease	0.000	0.995	0.005
K76.4 Peliosis hepatis	0.000	0.995	0.005
K76.3 Infarction of liver	0.000	0.995	0.005
K76.2 Central haemorrhagic necrosis of liver	0.000	0.995	0.005
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.000	0.995	0.004
J20.7 Acute bronchitis due to echovirus	0.000	0.995	0.004
J20.6 Acute bronchitis due to rhinovirus	0.000	0.995	0.004
J20.5 Acute bronchitis due to respiratory syncytial virus	0.000	0.995	0.004
J20.4 Acute bronchitis due to parainfluenza virus	0.000	0.995	0.004
J20.3 Acute bronchitis due to coxsackie virus	0.000	0.995	0.004
J20.2 Acute bronchitis due to streptococcus	0.000	0.995	0.004
J20.1 Acute bronchitis due to Haemophilus influenzae	0.000	0.995	0.004
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.000	0.995	0.004
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.995	0.005
K76.1 Chronic passive congestion of liver	0.000	0.995	0.005
T42.0 Hydantoin derivatives	0.004	0.995	0.000
T42.4 Benzodiazepines	0.005	0.995	0.000
D12.4 Descending colon	0.000	0.995	0.005
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.995	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.995	0.004
J21.8 Acute bronchiolitis due to other specified organisms	0.000	0.996	0.004
J21.1 Acute bronchiolitis due to human metapneumovirus	0.000	0.996	0.004
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.000	0.996	0.004
T36.0 Penicillins	0.004	0.996	0.000
E04 Other non-toxic goitre	0.000	0.996	0.004
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.996	0.004
J21.9 Acute bronchiolitis, unspecified	0.000	0.996	0.004
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.000	0.996	0.004
J20.8 Acute bronchitis due to other specified organisms	0.000	0.996	0.004
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.000	0.996	0.004
F45.8 Other somatoform disorders	0.000	0.996	0.004
M45 Ankylosing spondylitis	0.000	0.996	0.004
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.996	0.004
H01.8 Other specified inflammation of eyelid	0.000	0.996	0.004
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.996	0.004
O24 Diabetes mellitus in pregnancy	0.000	0.996	0.004
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.996	0.004
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.004	0.996	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.004	0.996	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.996	0.004
H72.2 Other marginal perforations of tympanic membrane	0.003	0.996	0.000
D12.8 Rectum	0.000	0.996	0.004
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.996	0.004
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.996	0.004
S90.9 Superficial injury of ankle and foot, unspecified	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.996	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.996	0.004
S32.0 Fracture of lumbar vertebra	0.000	0.996	0.004
I31 Other diseases of pericardium	0.000	0.996	0.004
G25.0 Essential tremor	0.004	0.996	0.000
C25.0 Head of pancreas	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.997	0.003
I31.9 Disease of pericardium, unspecified	0.000	0.997	0.003
I74 Arterial embolism and thrombosis	0.000	0.997	0.003
E04.8 Other specified non-toxic goitre	0.000	0.997	0.003
E06.9 Thyroiditis, unspecified	0.001	0.997	0.002
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.997	0.003
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
J36 Peritonsillar abscess	0.000	0.997	0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.997	0.003
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.997	0.003
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.997	0.003
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.997	0.003
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.997	0.003
H05.0 Acute inflammation of orbit	0.000	0.997	0.003
E04.0 Non-toxic diffuse goitre	0.000	0.997	0.003
U89.8 Agent resistant to other single specified antibiotic	0.003	0.997	0.000
Z29.2 Other prophylactic chemotherapy	0.003	0.997	0.000
J37 Chronic laryngitis and laryngotracheitis	0.000	0.997	0.003
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.997	0.003
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.997	0.003
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.997	0.003
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.997	0.003
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.997	0.003
J81 Pulmonary oedema	0.003	0.997	0.000
O80 Single spontaneous delivery	0.000	0.997	0.003
E05.9 Thyrotoxicosis, unspecified	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.000	0.997	0.003
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.997	0.003
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.997	0.003
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.997	0.003
K76.7 Hepatorenal syndrome	0.000	0.997	0.003
S32.01 Fracture of lumbar vertebra (open)	0.000	0.997	0.003
I31.8 Other specified diseases of pericardium	0.000	0.997	0.003
I31.2 Haemopericardium, not elsewhere classified	0.000	0.997	0.003
O80.8 Other single spontaneous delivery	0.000	0.997	0.003
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.997	0.003
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.997	0.003
N85.1 Endometrial adenomatous hyperplasia	0.000	0.997	0.003
J37.0 Chronic laryngitis	0.000	0.997	0.003
I31.0 Chronic adhesive pericarditis	0.000	0.997	0.003
Y45.2 Propionic acid derivatives	0.000	0.997	0.003
I31.1 Chronic constrictive pericarditis	0.000	0.997	0.003
J92.9 Pleural plaque without asbestos	0.000	0.997	0.003
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.997	0.003
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.997	0.003
O21.0 Mild hyperemesis gravidarum	0.000	0.997	0.003
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.997	0.000
T45.4 Iron and its compounds	0.002	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.997	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.997	0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.997	0.003
J37.1 Chronic laryngotracheitis	0.000	0.997	0.002
I86.8 Varicose veins of other specified sites	0.000	0.998	0.002
C25.9 Pancreas, unspecified	0.002	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations