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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17880984
log Bayes Factor = 14.3287
Chromosome 3   position 3,127,122  (GRCh37) Explore rs17880984 on Ensembl!
Variant rs17880984 is part of Cluster X0032

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
I30-I52 Other forms of heart disease
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
M05-M14 Inflammatory polyarthropathies
0.991 0.009 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
K90-K93 Other diseases of the digestive system
0.985 0.015 0.000
M06 Other rheumatoid arthritis
0.983 0.017 0.000
E65-E68 Obesity and other hyperalimentation
0.979 0.021 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.978 0.022 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.976 0.024 0.000
M06.9 Rheumatoid arthritis, unspecified
0.976 0.024 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.974 0.026 0.000
E66 Obesity
0.970 0.030 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.967 0.033 0.000
M80-M85 Disorders of bone density and structure
0.966 0.034 0.000
Chapter I Certain infectious and parasitic diseases
0.964 0.036 0.000
K92 Other diseases of digestive system
0.964 0.036 0.000
E66.9 Obesity, unspecified
0.962 0.038 0.000
Chapter V Mental and behavioural disorders
0.961 0.039 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.950 0.050 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.948 0.052 0.000
O36 Maternal care for other known or suspected foetal problems
0.948 0.052 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.948 0.052 0.000
M50-M54 Other dorsopathies
0.947 0.053 0.000
M81 Osteoporosis without pathological fracture
0.937 0.063 0.000
K70-K77 Diseases of liver
0.936 0.064 0.000
I95 Hypotension
0.931 0.069 0.000
S00-S09 Injuries to the head
0.929 0.071 0.000
I47 Paroxysmal tachycardia
0.922 0.078 0.000
M81.9 Osteoporosis, unspecified
0.912 0.088 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.909 0.091 0.000
K92.0 Haematemesis
0.905 0.095 0.000
T81 Complications of procedures, not elsewhere classified
0.905 0.095 0.000
O36.8 Maternal care for other specified foetal problems
0.903 0.097 0.000
S60-S69 Injuries to the wrist and hand
0.902 0.098 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.900 0.100 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.897 0.103 0.000
B25-B34 Other viral diseases
0.896 0.104 0.000
K92.1 Melaena
0.894 0.106 0.000
I95.9 Hypotension, unspecified
0.893 0.107 0.000
G40-G47 Episodic and paroxysmal disorders
0.892 0.108 0.000
M45-M49 Spondylopathies
0.889 0.111 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.888 0.112 0.000
M50 Cervical disk disorders
0.886 0.114 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.883 0.117 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.881 0.119 0.000
I35 Nonrheumatic aortic valve disorders
0.880 0.120 0.000
I47.1 Supraventricular tachycardia
0.873 0.127 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.871 0.129 0.000
I77 Other disorders of arteries and arterioles
0.871 0.129 0.000
G30-G32 Other degenerative diseases of the nervous system
0.864 0.136 0.000
A30-A49 Other bacterial diseases
0.862 0.138 0.000
I42 Cardiomyopathy
0.858 0.142 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.853 0.147 0.000
K90 Intestinal malabsorption
0.849 0.151 0.000
B34 Viral infection of unspecified site
0.847 0.153 0.000
K80 Cholelithiasis
0.845 0.155 0.000
E50-E64 Other nutritional deficiencies
0.840 0.160 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.838 0.162 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.835 0.165 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.835 0.165 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.833 0.167 0.000
K81 Cholecystitis
0.832 0.168 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.829 0.171 0.000
Y43 Primarily systemic agents
0.827 0.173 0.000
E20-E35 Disorders of other endocrine glands
0.823 0.177 0.000
I36 Nonrheumatic tricuspid valve disorders
0.821 0.179 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.819 0.181 0.000
O42 Premature rupture of membranes
0.819 0.181 0.000
I05-I09 Chronic rheumatic heart diseases
0.818 0.181 0.000
G43 Migraine
0.818 0.182 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.816 0.184 0.000
I71 Aortic aneurysm and dissection
0.816 0.184 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.815 0.185 0.000
Chapter II Neoplasms
0.814 0.186 0.000
B34.9 Viral infection, unspecified
0.813 0.187 0.000
I50 Heart failure
0.813 0.187 0.000
Chapter VIII Diseases of the ear and mastoid process
0.813 0.187 0.000
G70-G73 Diseases of myoneural junction and muscle
0.812 0.188 0.000
S80-S89 Injuries to the knee and lower leg
0.810 0.190 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.810 0.190 0.000
K70 Alcoholic liver disease
0.809 0.191 0.000
V10-V19 Pedal cyclist injured in transport accident
0.809 0.191 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.808 0.192 0.000
K04 Diseases of pulp and periapical tissues
0.807 0.193 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.806 0.193 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.806 0.194 0.000
M50.1 Cervical disk disorder with radiculopathy
0.803 0.197 0.000
I34 Nonrheumatic mitral valve disorders
0.803 0.197 0.000
O80-O84 Delivery
0.801 0.198 0.000
M91-M94 Chondropathies
0.799 0.201 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.798 0.202 0.000
K75 Other inflammatory liver diseases
0.797 0.202 0.000
A00-A09 Intestinal infectious diseases
0.796 0.204 0.000
S01 Open wound of head
0.794 0.206 0.000
M47 Spondylosis
0.792 0.208 0.000
M40-M43 Deforming dorsopathies
0.791 0.209 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.788 0.212 0.000
A41 Other septicaemia
0.788 0.212 0.000
I42.0 Dilated cardiomyopathy
0.787 0.213 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.786 0.214 0.000
K86 Other diseases of pancreas
0.785 0.215 0.000
O36.6 Maternal care for excessive foetal growth
0.785 0.215 0.000
K40-K46 Hernia
0.784 0.216 0.000
T86 Failure and rejection of transplanted organs and tissues
0.781 0.219 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.781 0.219 0.000
I77.6 Arteritis, unspecified
0.780 0.220 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
O40 Polyhydramnios
0.778 0.222 0.000
S40-S49 Injuries to the shoulder and upper arm
0.777 0.223 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.775 0.225 0.000
S50-S59 Injuries to the elbow and forearm
0.772 0.228 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.771 0.229 0.000
K92.9 Disease of digestive system, unspecified
0.770 0.230 0.000
Y43.3 Other antineoplastic drugs
0.769 0.231 0.000
I51 Complications and ill-defined descriptions of heart disease
0.766 0.233 0.000
I45 Other conduction disorders
0.766 0.234 0.000
M07 Psoriatic and enteropathic arthropathies
0.765 0.235 0.000
G43.9 Migraine, unspecified
0.765 0.235 0.000
F99-F99 Unspecified mental disorder
0.763 0.237 0.000
M50.2 Other cervical disk displacement
0.762 0.238 0.000
M86-M90 Other osteopathies
0.760 0.240 0.000
L20-L30 Dermatitis and eczema
0.760 0.240 0.000
E10-E14 Diabetes mellitus
0.760 0.240 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.758 0.242 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.758 0.242 0.000
K76 Other diseases of liver
0.758 0.242 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.758 0.242 0.000
E66.8 Other obesity
0.758 0.242 0.000
I73 Other peripheral vascular diseases
0.757 0.243 0.000
M53 Other dorsopathies, not elsewhere classified
0.756 0.244 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.756 0.244 0.000
M65-M68 Disorders of synovium and tendon
0.755 0.245 0.000
I84 Haemorrhoids
0.754 0.246 0.000
S62 Fracture at wrist and hand level
0.753 0.247 0.000
B15-B19 Viral hepatitis
0.752 0.247 0.000
K90.0 Coeliac disease
0.752 0.248 0.000
G40 Epilepsy
0.751 0.249 0.000
M13 Other arthritis
0.751 0.249 0.000
D00-D09 In situ neoplasms
0.751 0.249 0.000
G54 Nerve root and plexus disorders
0.750 0.250 0.000
M06.0 Seronegative rheumatoid arthritis
0.749 0.250 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.749 0.251 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.749 0.251 0.000
O48 Prolonged pregnancy
0.749 0.251 0.000
L40-L45 Papulosquamous disorders
0.749 0.251 0.000
S00 Superficial injury of head
0.749 0.251 0.000
Y86 Sequelae of other accidents
0.748 0.251 0.000
F10.2 Dependence syndrome
0.747 0.253 0.000
I31 Other diseases of pericardium
0.747 0.253 0.000
S20-S29 Injuries to the thorax
0.746 0.254 0.000
W20-W49 Exposure to inanimate mechanical forces
0.745 0.254 0.000
O42.9 Premature rupture of membranes, unspecified
0.744 0.256 0.000
K82 Other diseases of gallbladder
0.744 0.256 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.258 0.000
O47 False labour
0.742 0.258 0.000
E70-E90 Metabolic disorders
0.741 0.259 0.000
M54 Dorsalgia
0.739 0.261 0.000
I35.8 Other aortic valve disorders
0.737 0.263 0.000
K40 Inguinal hernia
0.736 0.264 0.000
C51-C58 Malignant neoplasms of female genital organs
0.736 0.264 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.736 0.264 0.000
S90-S99 Injuries to the ankle and foot
0.735 0.265 0.000
M80 Osteoporosis with pathological fracture
0.734 0.266 0.000
G51 Facial nerve disorders
0.733 0.266 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.733 0.266 0.000
G56 Mononeuropathies of upper limb
0.733 0.267 0.000
F10.0 Acute intoxication
0.733 0.267 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.733 0.267 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.732 0.268 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.731 0.268 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.731 0.269 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.729 0.271 0.000
E61 Deficiency of other nutrient elements
0.728 0.272 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.727 0.273 0.000
K81.0 Acute cholecystitis
0.727 0.273 0.000
I35.0 Aortic (valve) stenosis
0.727 0.273 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.725 0.274 0.000
D05 Carcinoma in situ of breast
0.724 0.276 0.000
K91.3 Postoperative intestinal obstruction
0.723 0.277 0.000
V20-V29 Motorcycle rider injured in transport accident
0.723 0.277 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.722 0.278 0.000
S02 Fracture of skull and facial bones
0.722 0.278 0.000
K65-K67 Diseases of peritoneum
0.722 0.278 0.000
F30-F39 Mood [affective] disorders
0.721 0.279 0.000
M81.4 Drug-induced osteoporosis
0.721 0.279 0.000
S09 Other and unspecified injuries of head
0.720 0.280 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.719 0.280 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.719 0.281 0.000
I46 Cardiac arrest
0.718 0.281 0.000
I95.1 Orthostatic hypotension
0.718 0.282 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.718 0.282 0.000
X60-X84 Intentional self-harm
0.718 0.282 0.000
K13 Other diseases of lip and oral mucosa
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
G30 Alzheimer's disease
0.717 0.283 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.716 0.284 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.715 0.285 0.000
A04 Other bacterial intestinal infections
0.714 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.713 0.287 0.000
F80-F89 Disorders of psychological development
0.713 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
I33 Acute and subacute endocarditis
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
I30 Acute pericarditis
0.712 0.288 0.000
E40-E46 Malnutrition
0.711 0.289 0.000
G90-G99 Other disorders of the nervous system
0.711 0.289 0.000
M14 Arthropathies in other diseases classified elsewhere
0.710 0.290 0.000
M12 Other specific arthropathies
0.710 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.710 0.290 0.000
M08 Juvenile arthritis
0.710 0.290 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.710 0.290 0.000
O85-O92 Complications predominantly related to the puerperium
0.709 0.291 0.000
I97.1 Other functional disturbances following cardiac surgery
0.709 0.291 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.709 0.291 0.000
B35-B49 Mycoses
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.292 0.000
Y10-Y34 Event of undetermined intent
0.707 0.292 0.000
Y00-Y09 Assault
0.707 0.292 0.000
X85-X99 Assault
0.707 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.292 0.000
X50-X57 Overexertion, travel and privation
0.707 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.707 0.292 0.000
X30-X39 Exposure to forces of nature
0.707 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.292 0.000
X10-X19 Contact with heat and hot substances
0.707 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.292 0.000
W75-W84 Other accidental threats to breathing
0.707 0.292 0.000
W65-W74 Accidental drowning and submersion
0.707 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.292 0.000
V95-V97 Air and space transport accidents
0.707 0.292 0.000
V90-V94 Water transport accidents
0.707 0.292 0.000
V80-V89 Other land transport accidents
0.707 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.707 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.292 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.706 0.293 0.000
W00-W19 Falls
0.706 0.294 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.706 0.294 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.705 0.295 0.000
M06.8 Other specified rheumatoid arthritis
0.705 0.295 0.000
M06.4 Inflammatory polyarthropathy
0.705 0.295 0.000
M06.3 Rheumatoid nodule
0.705 0.295 0.000
M06.2 Rheumatoid bursitis
0.705 0.295 0.000
M06.1 Adult-onset Still's disease
0.705 0.295 0.000
S61 Open wound of wrist and hand
0.704 0.295 0.000
K04.8 Radicular cyst
0.704 0.296 0.000
M45 Ankylosing spondylitis
0.702 0.298 0.000
E67 Other hyperalimentation
0.702 0.298 0.000
E68 Sequelae of hyperalimentation
0.702 0.298 0.000
E65 Localised adiposity
0.702 0.298 0.000
I74 Arterial embolism and thrombosis
0.701 0.298 0.000
O45 Premature separation of placenta [abruptio placentae]
0.701 0.299 0.000
O44 Placenta praevia
0.701 0.299 0.000
O43 Placental disorders
0.701 0.299 0.000
O41 Other disorders of amniotic fluid and membranes
0.701 0.299 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.701 0.299 0.000
O33 Maternal care for known or suspected disproportion
0.701 0.299 0.000
O31 Complications specific to multiple gestation
0.701 0.299 0.000
O30 Multiple gestation
0.701 0.299 0.000
M70-M79 Other soft tissue disorders
0.701 0.299 0.000
Chapter XXII Codes for special purposes
0.700 0.300 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.700 0.300 0.000
T87 Complications peculiar to reattachment and amputation
0.700 0.300 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.700 0.300 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.700 0.300 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.700 0.300 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.700 0.300 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.700 0.300 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.700 0.300 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.700 0.300 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.700 0.300 0.000
S06 Intracranial injury
0.700 0.300 0.000
M47.9 Spondylosis, unspecified
0.699 0.301 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.698 0.302 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.698 0.302 0.000
I99 Other and unspecified disorders of circulatory system
0.698 0.302 0.000
M05 Seropositive rheumatoid arthritis
0.697 0.303 0.000
M15-M19 Arthrosis
0.697 0.303 0.000
H80-H83 Diseases of inner ear
0.697 0.303 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.696 0.304 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.696 0.304 0.000
E66.1 Drug-induced obesity
0.696 0.304 0.000
E66.0 Obesity due to excess calories
0.696 0.304 0.000
S64 Injury of nerves at wrist and hand level
0.696 0.304 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.695 0.305 0.000
I38 Endocarditis, valve unspecified
0.695 0.305 0.000
M11 Other crystal arthropathies
0.694 0.306 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.694 0.306 0.000
S70-S79 Injuries to the hip and thigh
0.693 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.693 0.307 0.000
M85 Other disorders of bone density and structure
0.692 0.308 0.000
M84 Disorders of continuity of bone
0.692 0.308 0.000
M83 Adult osteomalacia
0.692 0.308 0.000
M82 Osteoporosis in diseases classified elsewhere
0.692 0.308 0.000
B99-B99 Other infectious diseases
0.691 0.309 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.691 0.309 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.691 0.309 0.000
B65-B83 Helminthiases
0.691 0.309 0.000
B50-B64 Protozoal diseases
0.691 0.309 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.309 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.691 0.309 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.309 0.000
A75-A79 Rickettsioses
0.691 0.309 0.000
A70-A74 Other diseases caused by chlamydiae
0.691 0.309 0.000
A65-A69 Other spirochaetal diseases
0.691 0.309 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.691 0.309 0.000
A20-A28 Certain zoonotic bacterial diseases
0.691 0.309 0.000
A15-A19 Tuberculosis
0.691 0.309 0.000
K92.8 Other specified diseases of digestive system
0.691 0.309 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.691 0.309 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.690 0.310 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.690 0.310 0.000
K70.1 Alcoholic hepatitis
0.689 0.311 0.000
Y40 Systemic antibiotics
0.689 0.311 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.689 0.311 0.000
F70-F79 Mental retardation
0.689 0.311 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.689 0.311 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.689 0.311 0.000
I85 Oesophageal varices
0.689 0.311 0.000
K12 Stomatitis and related lesions
0.688 0.312 0.000
K02 Dental caries
0.686 0.314 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.684 0.316 0.000
F10.3 Withdrawal state
0.684 0.316 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.683 0.317 0.000
K10 Other diseases of jaws
0.683 0.317 0.000
I84.1 Internal haemorrhoids with other complications
0.683 0.317 0.000
K74 Fibrosis and cirrhosis of liver
0.682 0.318 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.682 0.318 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.681 0.319 0.000
I72 Other aneurysm
0.681 0.319 0.000
I70 Atherosclerosis
0.681 0.319 0.000
S69 Other and unspecified injuries of wrist and hand
0.681 0.319 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.681 0.319 0.000
I73.0 Raynaud's syndrome
0.681 0.319 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.681 0.319 0.000
G70 Myasthenia gravis and other myoneural disorders
0.680 0.320 0.000
K08 Other disorders of teeth and supporting structures
0.680 0.320 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.680 0.320 0.000
O36.9 Maternal care for foetal problem, unspecified
0.679 0.320 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.679 0.320 0.000
O36.5 Maternal care for poor foetal growth
0.679 0.320 0.000
O36.4 Maternal care for intra-uterine death
0.679 0.320 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.679 0.320 0.000
O36.2 Maternal care for hydrops foetalis
0.679 0.320 0.000
O36.1 Maternal care for other isoimmunisation
0.679 0.320 0.000
E23 Hypofunction and other disorders of pituitary gland
0.680 0.320 0.000
G58 Other mononeuropathies
0.679 0.321 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.679 0.321 0.000
G52 Disorders of other cranial nerves
0.679 0.321 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.679 0.321 0.000
I87 Other disorders of veins
0.679 0.321 0.000
Y84.6 Urinary catheterisation
0.678 0.322 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.677 0.323 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.675 0.325 0.000
M10 Gout
0.674 0.326 0.000
I08 Multiple valve diseases
0.672 0.328 0.000
M50.0 Cervical disk disorder with myelopathy
0.672 0.328 0.000
M81.8 Other osteoporosis
0.672 0.328 0.000
M81.6 Localised osteoporosis [Lequesne]
0.672 0.328 0.000
M81.5 Idiopathic osteoporosis
0.672 0.328 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.672 0.328 0.000
M81.2 Osteoporosis of disuse
0.672 0.328 0.000
M81.1 Postoophorectomy osteoporosis
0.672 0.328 0.000
M81.0 Postmenopausal osteoporosis
0.672 0.328 0.000
T18 Foreign body in alimentary tract
0.672 0.328 0.000
D05.1 Intraductal carcinoma in situ
0.672 0.328 0.000
K77 Liver disorders in diseases classified elsewhere
0.671 0.329 0.000
K73 Chronic hepatitis, not elsewhere classified
0.671 0.329 0.000
K72 Hepatic failure, not elsewhere classified
0.671 0.329 0.000
K71 Toxic liver disease
0.671 0.329 0.000
I27 Other pulmonary heart diseases
0.671 0.329 0.000
G35 Multiple sclerosis
0.670 0.330 0.000
S60 Superficial injury of wrist and hand
0.670 0.330 0.000
A41.9 Septicaemia, unspecified
0.669 0.331 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.668 0.331 0.000
I95.8 Other hypotension
0.667 0.333 0.000
I95.2 Hypotension due to drugs
0.667 0.333 0.000
I95.0 Idiopathic hypotension
0.667 0.333 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.666 0.334 0.000
S08 Traumatic amputation of part of head
0.666 0.334 0.000
S07 Crushing injury of head
0.666 0.334 0.000
S05 Injury of eye and orbit
0.666 0.334 0.000
S04 Injury of cranial nerves
0.666 0.334 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.666 0.334 0.000
M54.9 Dorsalgia, unspecified
0.665 0.335 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.665 0.335 0.000
K85 Acute pancreatitis
0.665 0.335 0.000
I77.1 Stricture of artery
0.664 0.336 0.000
G47 Sleep disorders
0.663 0.336 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.662 0.338 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.662 0.338 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.661 0.338 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.661 0.339 0.000
I47.0 Reentry ventricular arrhythmia
0.661 0.339 0.000
O00-O08 Pregnancy with abortive outcome
0.661 0.339 0.000
I26 Pulmonary embolism
0.659 0.341 0.000
I84.6 Residual haemorrhoidal skin tags
0.658 0.342 0.000
L40 Psoriasis
0.658 0.342 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.657 0.343 0.000
K75.9 Inflammatory liver disease, unspecified
0.657 0.343 0.000
M93 Other osteochondropathies
0.655 0.345 0.000
G50 Disorders of trigeminal nerve
0.654 0.346 0.000
M81.98 Osteoporosis, unspecified (Other)
0.654 0.346 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.654 0.346 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.654 0.346 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.654 0.346 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.654 0.346 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.654 0.346 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.654 0.346 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.654 0.346 0.000
K46 Unspecified abdominal hernia
0.653 0.347 0.000
M51 Other intervertebral disk disorders
0.652 0.348 0.000
I47.2 Ventricular tachycardia
0.652 0.348 0.000
K05 Gingivitis and periodontal diseases
0.652 0.348 0.000
Y59 Other and unspecified vaccines and biological substances
0.651 0.348 0.000
Y58 Bacterial vaccines
0.651 0.348 0.000
Y57 Other and unspecified drugs and medicaments
0.651 0.348 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.651 0.348 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.651 0.348 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.651 0.348 0.000
Y52 Agents primarily affecting the cardiovascular system
0.651 0.348 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.651 0.348 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.651 0.348 0.000
Y48 Anaesthetics and therapeutic gases
0.651 0.348 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.651 0.348 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.651 0.348 0.000
Y44 Agents primarily affecting blood constituents
0.651 0.348 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.651 0.348 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.651 0.349 0.000
G20-G26 Extrapyramidal and movement disorders
0.650 0.350 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.649 0.351 0.000
L50-L54 Urticaria and erythema
0.649 0.351 0.000
T81.9 Unspecified complication of procedure
0.649 0.351 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.649 0.351 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.649 0.351 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.649 0.351 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.649 0.351 0.000
E61.1 Iron deficiency
0.648 0.352 0.000
S67 Crushing injury of wrist and hand
0.647 0.353 0.000
S65 Injury of blood vessels at wrist and hand level
0.647 0.353 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.647 0.353 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.645 0.354 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.645 0.354 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.645 0.354 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.645 0.354 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.645 0.354 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.645 0.354 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.645 0.354 0.000
F11 Mental and behavioural disorders due to use of opioids
0.645 0.354 0.000
C56 Malignant neoplasm of ovary
0.645 0.355 0.000
O80 Single spontaneous delivery
0.645 0.355 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.645 0.355 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.645 0.355 0.000
I51.9 Heart disease, unspecified
0.644 0.356 0.000
K09 Cysts of oral region, not elsewhere classified
0.643 0.357 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.643 0.357 0.000
K03 Other diseases of hard tissues of teeth
0.643 0.357 0.000
K00 Disorders of tooth development and eruption
0.643 0.357 0.000
I49 Other cardiac arrhythmias
0.643 0.357 0.000
M43 Other deforming dorsopathies
0.643 0.357 0.000
B33 Other viral diseases, not elsewhere classified
0.642 0.357 0.000
B30 Viral conjunctivitis
0.642 0.357 0.000
B27 Infectious mononucleosis
0.642 0.357 0.000
B26 Mumps
0.642 0.357 0.000
B25 Cytomegaloviral disease
0.642 0.357 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.642 0.358 0.000
I50.9 Heart failure, unspecified
0.642 0.358 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.641 0.359 0.000
K81.1 Chronic cholecystitis
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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