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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523860
log Bayes Factor = 135.849
Chromosome 6   position 31,045,574  (GRCh37) Explore rs2523860 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40 Psoriasis
0.999 0.001 0.000
E07 Other disorders of thyroid
0.000 0.002 0.998
E07.9 Disorder of thyroid, unspecified
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.006 0.994
L40.5 Arthropathic psoriasis
0.992 0.008 0.000
L40.0 Psoriasis vulgaris
0.987 0.013 0.000
E83.1 Disorders of iron metabolism
0.931 0.069 0.000
C61 Malignant neoplasm of prostate
0.907 0.093 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.165 0.835
K90 Intestinal malabsorption
0.000 0.174 0.826
E03.8 Other specified hypothyroidism
0.000 0.181 0.819
L40.4 Guttate psoriasis
0.815 0.185 0.000
L40.3 Pustulosis palmaris et plantaris
0.788 0.212 0.000
L40.1 Generalised pustular psoriasis
0.761 0.239 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.239 0.761
E06 Thyroiditis
0.000 0.243 0.757
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.255 0.745
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.716 0.283 0.000
E07.1 Dyshormogenetic goitre
0.000 0.284 0.715
E07.0 Hypersecretion of calcitonin
0.000 0.284 0.715
K90.9 Intestinal malabsorption, unspecified
0.000 0.301 0.699
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.302 0.698
E07.8 Other specified disorders of thyroid
0.000 0.313 0.687
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.315 0.685
L40.8 Other psoriasis
0.667 0.332 0.000
E06.3 Autoimmune thyroiditis
0.000 0.370 0.630
K90.8 Other intestinal malabsorption
0.000 0.373 0.627
E05.8 Other thyrotoxicosis
0.000 0.388 0.611
E06.5 Other chronic thyroiditis
0.000 0.390 0.609
E03.1 Congenital hypothyroidism without goitre
0.000 0.394 0.606
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.397 0.603
K90.3 Pancreatic steatorrhoea
0.000 0.408 0.592
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.408 0.592
K90.1 Tropical sprue
0.000 0.408 0.592
E06.4 Drug-induced thyroiditis
0.000 0.457 0.543
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.457 0.543
E06.0 Acute thyroiditis
0.000 0.457 0.543
E06.1 Subacute thyroiditis
0.000 0.469 0.530
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M35.0 Sicca syndrome [Sjogren]
0.000 0.560 0.440
E06.9 Thyroiditis, unspecified
0.000 0.643 0.357
C60-C63 Malignant neoplasms of male genital organs
0.301 0.699 0.000
L40-L45 Papulosquamous disorders
0.248 0.752 0.000
C60 Malignant neoplasm of penis
0.231 0.769 0.000
E10.9 Without complications
0.000 0.783 0.217
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.786 0.214
E10 Insulin-dependent diabetes mellitus
0.000 0.789 0.211
C63 Malignant neoplasm of other and unspecified male genital organs
0.208 0.792 0.000
E10-E14 Diabetes mellitus
0.000 0.793 0.207
E10.3 With ophthalmic complications
0.000 0.799 0.201
L41 Parapsoriasis
0.197 0.802 0.000
E10.2 With renal complications
0.000 0.819 0.181
C60.9 Penis, unspecified
0.179 0.821 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.178 0.822 0.000
L44 Other papulosquamous disorders
0.177 0.823 0.000
C60.1 Glans penis
0.176 0.824 0.000
M35 Other systemic involvement of connective tissue
0.000 0.827 0.173
H00.1 Chalazion
0.167 0.833 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.834 0.166
C60.8 Overlapping lesion of penis
0.166 0.834 0.000
C60.2 Body of penis
0.166 0.834 0.000
C62 Malignant neoplasm of testis
0.165 0.835 0.000
L41.1 Pityriasis lichenoides chronica
0.162 0.838 0.000
E28 Ovarian dysfunction
0.000 0.840 0.160
C60.0 Prepuce
0.157 0.843 0.000
L42 Pityriasis rosea
0.155 0.844 0.000
E10.7 With multiple complications
0.000 0.847 0.153
E14 Unspecified diabetes mellitus
0.000 0.847 0.153
E28.3 Primary ovarian failure
0.000 0.847 0.153
E10.0 With coma
0.000 0.850 0.150
C63.9 Male genital organ, unspecified
0.149 0.851 0.000
C63.8 Overlapping lesion of male genital organs
0.149 0.851 0.000
C63.7 Other specified male genital organs
0.149 0.851 0.000
C63.1 Spermatic cord
0.149 0.851 0.000
C63.0 Epididymis
0.149 0.851 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.852 0.148
M35.7 Hypermobility syndrome
0.000 0.854 0.146
E24 Cushing's syndrome
0.000 0.857 0.143
E23 Hypofunction and other disorders of pituitary gland
0.000 0.857 0.143
E10.4 With neurological complications
0.000 0.857 0.143
L41.9 Parapsoriasis, unspecified
0.142 0.858 0.000
L41.8 Other parapsoriasis
0.142 0.858 0.000
L41.5 Retiform parapsoriasis
0.142 0.858 0.000
L41.4 Large plaque parapsoriasis
0.142 0.858 0.000
L41.3 Small plaque parapsoriasis
0.142 0.858 0.000
L41.2 Lymphomatoid papulosis
0.142 0.858 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.142 0.858 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.858 0.142
C63.2 Scrotum
0.141 0.859 0.000
E14.3 With ophthalmic complications
0.000 0.862 0.138
E40-E46 Malnutrition
0.000 0.863 0.137
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.863 0.137
E28.2 Polycystic ovarian syndrome
0.000 0.867 0.133
E10.8 With unspecified complications
0.000 0.869 0.131
M35.1 Other overlap syndromes
0.000 0.870 0.130
E23.2 Diabetes insipidus
0.000 0.870 0.130
E13 Other specified diabetes mellitus
0.000 0.871 0.129
M35.8 Other specified systemic involvement of connective tissue
0.000 0.871 0.128
E24.2 Drug-induced Cushing's syndrome
0.000 0.872 0.128
E10.6 With other specified complications
0.000 0.872 0.127
E21.3 Hyperparathyroidism, unspecified
0.000 0.872 0.128
L44.9 Papulosquamous disorder, unspecified
0.127 0.873 0.000
L44.8 Other specified papulosquamous disorders
0.127 0.873 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.127 0.873 0.000
L44.3 Lichen ruber moniliformis
0.127 0.873 0.000
L44.2 Lichen striatus
0.127 0.873 0.000
L44.1 Lichen nitidus
0.127 0.873 0.000
L44.0 Pityriasis rubra pilaris
0.126 0.874 0.000
M35.2 Behcet's disease
0.000 0.874 0.126
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.876 0.124
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.876 0.124
M35.5 Multifocal fibrosclerosis
0.000 0.876 0.124
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.876 0.124
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.880 0.119
E32 Diseases of thymus
0.000 0.880 0.119
E30 Disorders of puberty, not elsewhere classified
0.000 0.880 0.119
E14.5 With peripheral circulatory complications
0.000 0.881 0.119
C62.0 Undescended testis
0.118 0.881 0.000
E31 Polyglandular dysfunction
0.000 0.883 0.117
E28.9 Ovarian dysfunction, unspecified
0.000 0.885 0.115
E28.8 Other ovarian dysfunction
0.000 0.885 0.115
E28.1 Androgen excess
0.000 0.885 0.115
E28.0 Oestrogen excess
0.000 0.885 0.115
C83.3 Large cell (diffuse)
0.000 0.886 0.114
C62.1 Descended testis
0.114 0.886 0.000
E14.1 With ketoacidosis
0.000 0.887 0.113
E14.8 With unspecified complications
0.000 0.887 0.113
E23.6 Other disorders of pituitary gland
0.000 0.887 0.113
E23.7 Disorder of pituitary gland, unspecified
0.000 0.887 0.113
E14.7 With multiple complications
0.000 0.890 0.110
E14.0 With coma
0.000 0.890 0.110
E14.6 With other specified complications
0.000 0.891 0.109
E10.5 With peripheral circulatory complications
0.000 0.893 0.107
E12.9 Without complications
0.000 0.893 0.106
E12.8 With unspecified complications
0.000 0.893 0.106
E12.7 With multiple complications
0.000 0.893 0.106
E12.6 With other specified complications
0.000 0.893 0.106
E12.5 With peripheral circulatory complications
0.000 0.893 0.106
E12.4 With neurological complications
0.000 0.893 0.106
E12.3 With ophthalmic complications
0.000 0.893 0.106
E12.2 With renal complications
0.000 0.893 0.106
E12.1 With ketoacidosis
0.000 0.893 0.106
E12.0 With coma
0.000 0.893 0.106
E14.2 Withrenal complications
0.000 0.894 0.106
E24.0 Pituitary-dependent Cushing's disease
0.000 0.894 0.106
E26 Hyperaldosteronism
0.000 0.894 0.105
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.895 0.105
E25 Adrenogenital disorders
0.000 0.896 0.104
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.896 0.104
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.897 0.103
E24.3 Ectopic ACTH syndrome
0.000 0.897 0.103
E24.1 Nelson's syndrome
0.000 0.897 0.103
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.897 0.103
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.897 0.102
E23.1 Drug-induced hypopituitarism
0.000 0.897 0.102
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.898 0.102
E15 Nondiabetic hypoglycaemic coma
0.000 0.898 0.102
E13.3 With ophthalmic complications
0.000 0.899 0.101
E24.8 Other Cushing's syndrome
0.000 0.899 0.101
C85.1 B-cell lymphoma, unspecified
0.000 0.899 0.101
H00 Hordeolum and chalazion
0.100 0.900 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.900 0.100
E21.2 Other hyperparathyroidism
0.000 0.900 0.100
E20 Hypoparathyroidism
0.000 0.900 0.099
E29 Testicular dysfunction
0.000 0.901 0.099
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.901 0.098
E45 Retarded development following protein-energy malnutrition
0.000 0.901 0.098
E43 Unspecified severe protein-energy malnutrition
0.000 0.901 0.098
E42 Marasmic kwashiorkor
0.000 0.901 0.098
E41 Nutritional marasmus
0.000 0.901 0.098
E40 Kwashiorkor
0.000 0.901 0.098
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.901 0.099
E14.4 With neurological complications
0.000 0.902 0.098
E24.9 Cushing's syndrome, unspecified
0.000 0.903 0.097
C81 Hodgkin's disease
0.000 0.903 0.097
E50-E64 Other nutritional deficiencies
0.000 0.904 0.096
E13.8 With unspecified complications
0.000 0.907 0.093
E13.7 With multiple complications
0.000 0.907 0.093
E13.6 With other specified complications
0.000 0.907 0.093
E13.5 With peripheral circulatory complications
0.000 0.907 0.093
E13.4 With neurological complications
0.000 0.907 0.093
E13.2 With renal complications
0.000 0.907 0.093
E13.1 With ketoacidosis
0.000 0.907 0.093
E13.0 With coma
0.000 0.907 0.093
E21.4 Other specified disorders of parathyroid gland
0.000 0.908 0.092
E10.1 With ketoacidosis
0.000 0.909 0.091
E16 Other disorders of pancreatic internal secretion
0.000 0.910 0.090
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.911 0.089
C81.9 Hodgkin's disease, unspecified
0.000 0.911 0.089
K60.2 Anal fissure, unspecified
0.000 0.913 0.087
L43 Lichen planus
0.087 0.913 0.001
H00.0 Hordeolum and other deep inflammation of eyelid
0.087 0.913 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.913 0.087
E30.9 Disorder of puberty, unspecified
0.000 0.914 0.086
E30.8 Other disorders of puberty
0.000 0.914 0.086
E30.1 Precocious puberty
0.000 0.914 0.086
E30.0 Delayed puberty
0.000 0.914 0.086
E32.9 Disease of thymus, unspecified
0.000 0.914 0.086
E32.8 Other diseases of thymus
0.000 0.914 0.086
E32.1 Abscess of thymus
0.000 0.914 0.086
E32.0 Persistent hyperplasia of thymus
0.000 0.914 0.086
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.914 0.086
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.914 0.086
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.914 0.086
E34 Other endocrine disorders
0.000 0.915 0.085
E31.9 Polyglandular dysfunction, unspecified
0.000 0.916 0.084
E31.8 Other polyglandular dysfunction
0.000 0.916 0.084
E31.1 Polyglandular hyperfunction
0.000 0.916 0.084
C81.2 Mixed cellularity
0.000 0.916 0.084
C83.7 Burkitt's tumour
0.000 0.916 0.084
E31.0 Autoimmune polyglandular failure
0.000 0.918 0.082
E46 Unspecified protein-energy malnutrition
0.000 0.918 0.082
K60 Fissure and fistula of anal and rectal regions
0.000 0.919 0.081
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.921 0.079
E22 Hyperfunction of pituitary gland
0.000 0.921 0.079
C81.1 Nodular sclerosis
0.000 0.922 0.078
C83.1 Small cleaved cell (diffuse)
0.000 0.922 0.078
K60.0 Acute anal fissure
0.000 0.923 0.077
C81.0 Lymphocytic predominance
0.000 0.923 0.077
E26.9 Hyperaldosteronism, unspecified
0.000 0.924 0.076
E26.8 Other hyperaldosteronism
0.000 0.924 0.076
E26.1 Secondary hyperaldosteronism
0.000 0.924 0.076
C62.9 Testis, unspecified
0.076 0.924 0.000
K60.3 Anal fistula
0.000 0.924 0.076
C85.0 Lymphosarcoma
0.000 0.925 0.075
E25.9 Adrenogenital disorder, unspecified
0.000 0.925 0.075
E25.8 Other adrenogenital disorders
0.000 0.925 0.075
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.925 0.075
C83.6 Undifferentiated (diffuse)
0.000 0.926 0.074
C83.4 Immunoblastic (diffuse)
0.000 0.926 0.074
C83.2 Mixed small and large cell (diffuse)
0.000 0.926 0.074
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.927 0.073
E51 Thiamine deficiency
0.000 0.927 0.073
E58 Dietary calcium deficiency
0.000 0.928 0.072
E20.1 Pseudohypoparathyroidism
0.000 0.928 0.071
E20.0 Idiopathic hypoparathyroidism
0.000 0.928 0.071
C86 Other specified types of T/NK-cell lymphoma
0.000 0.929 0.071
E56 Other vitamin deficiencies
0.000 0.929 0.071
E29.8 Other testicular dysfunction
0.000 0.929 0.071
E29.0 Testicular hyperfunction
0.000 0.929 0.071
E44.1 Mild protein-energy malnutrition
0.000 0.929 0.071
E44.0 Moderate protein-energy malnutrition
0.000 0.929 0.071
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.929 0.071
E34.8 Other specified endocrine disorders
0.000 0.930 0.070
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.930 0.070
E29.9 Testicular dysfunction, unspecified
0.000 0.930 0.070
E65-E68 Obesity and other hyperalimentation
0.000 0.930 0.070
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.930 0.070
C81.3 Lymphocytic depletion
0.000 0.930 0.070
K60.5 Anorectal fistula
0.000 0.931 0.069
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.931 0.069
E63 Other nutritional deficiencies
0.000 0.931 0.069
E50 Vitamin A deficiency
0.000 0.931 0.069
E60 Dietary zinc deficiency
0.000 0.931 0.069
E59 Dietary selenium deficiency
0.000 0.931 0.069
E52 Niacin deficiency [pellagra]
0.000 0.931 0.069
C93 Monocytic leukaemia
0.000 0.931 0.069
E20.8 Other hypoparathyroidism
0.000 0.932 0.067
E61 Deficiency of other nutrient elements
0.000 0.933 0.067
C83.5 Lymphoblastic (diffuse)
0.000 0.933 0.067
C94 Other leukaemias of specified cell type
0.000 0.934 0.066
C88 Malignant immunoproliferative diseases
0.000 0.935 0.065
C81.7 Other Hodgkin's disease
0.000 0.935 0.065
E34.3 Short stature, not elsewhere classified
0.000 0.935 0.065
C95 Leukaemia of unspecified cell type
0.000 0.935 0.065
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.935 0.065
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.935 0.065
E16.4 Abnormal secretion of gastrin
0.000 0.935 0.065
E16.3 Increased secretion of glucagon
0.000 0.935 0.065
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.936 0.064
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.936 0.063
L43.3 Subacute (active) lichen planus
0.062 0.937 0.001
L43.2 Lichenoid drug reaction
0.062 0.937 0.001
L43.1 Bullous lichen planus
0.062 0.937 0.001
L43.0 Hypertrophic lichen planus
0.062 0.937 0.001
K60.4 Rectal fistula
0.000 0.938 0.062
E26.0 Primary hyperaldosteronism
0.000 0.938 0.062
E54 Ascorbic acid deficiency
0.000 0.938 0.061
C82.3 Follicular lymphoma grade IIIa
0.000 0.938 0.061
E34.5 Androgen resistance syndrome
0.000 0.938 0.061
E34.4 Constitutional tall stature
0.000 0.938 0.061
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.938 0.061
E34.1 Other hypersecretion of intestinal hormones
0.000 0.938 0.061
C92 Myeloid leukaemia
0.000 0.939 0.061
Z51.3 Blood transfusion without reported diagnosis
0.000 0.940 0.060
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.940 0.060
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.940 0.060
E16.1 Other hypoglycaemia
0.000 0.940 0.060
E04 Other non-toxic goitre
0.000 0.940 0.059
C92.1 Chronic myeloid leukaemia
0.000 0.941 0.059
E13.9 Without complications
0.000 0.942 0.057
E20.9 Hypoparathyroidism, unspecified
0.000 0.943 0.057
C84.0 Mycosis fungoides
0.000 0.943 0.057
E22.8 Other hyperfunction of pituitary gland
0.000 0.943 0.057
E51.2 Wernicke's encephalopathy
0.000 0.943 0.057
C82.2 Large cell, follicular
0.000 0.943 0.057
E21.0 Primary hyperparathyroidism
0.000 0.945 0.055
C82.6 Cutaneous follicle centre lymphoma
0.000 0.946 0.054
C82.5 Diffuse follicle centre lymphoma
0.000 0.946 0.054
E56.1 Deficiency of vitamin K
0.000 0.946 0.054
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.946 0.053
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.946 0.053
E61.2 Magnesium deficiency
0.000 0.947 0.053
E51.9 Thiamine deficiency, unspecified
0.000 0.947 0.052
E51.8 Other manifestations of thiamine deficiency
0.000 0.947 0.052
E51.1 Beriberi
0.000 0.947 0.052
E29.1 Testicular hypofunction
0.000 0.948 0.052
C84.5 Other and unspecified T-cell lymphomas
0.000 0.948 0.052
L43.8 Other lichen planus
0.051 0.948 0.001
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.948 0.052
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.948 0.052
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.949 0.051
C86.4 Blastic NK-cell lymphoma
0.000 0.949 0.051
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.949 0.051
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.949 0.051
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.949 0.051
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.949 0.051
E56.9 Vitamin deficiency, unspecified
0.000 0.949 0.051
E56.8 Deficiency of other vitamins
0.000 0.949 0.051
E56.0 Deficiency of vitamin E
0.000 0.949 0.051
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.949 0.051
C96.8 Histiocytic sarcoma
0.000 0.949 0.051
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.949 0.051
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.949 0.051
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.949 0.051
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.949 0.051
C96.3 True histiocytic lymphoma
0.000 0.949 0.051
C96.2 Malignant mast cell tumour
0.000 0.949 0.051
C96.1 Malignant histiocytosis
0.000 0.949 0.051
C96.0 Letterer-Siwe disease
0.000 0.949 0.051
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.950 0.050
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.950 0.050
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.950 0.050
C84.3 Lymphoepithelioid lymphoma
0.000 0.950 0.050
C84.2 T-zone lymphoma
0.000 0.950 0.050
C84.1 Sezary's diease
0.000 0.950 0.050
E67 Other hyperalimentation
0.000 0.950 0.050
E68 Sequelae of hyperalimentation
0.000 0.950 0.050
E23.0 Hypopituitarism
0.000 0.950 0.050
E50.9 Vitamin A deficiency, unspecified
0.000 0.950 0.049
E50.8 Other manifestations of vitamin A deficiency
0.000 0.950 0.049
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.950 0.049
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.950 0.049
E50.5 Vitamin A deficiency with night blindness
0.000 0.950 0.049
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.950 0.049
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.950 0.049
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.950 0.049
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.950 0.049
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.950 0.049
E63.9 Nutritional deficiency, unspecified
0.000 0.950 0.049
E63.8 Other specified nutritional deficiencies
0.000 0.950 0.049
E63.1 Imbalance of constituents of food intake
0.000 0.950 0.049
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.950 0.049
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.950 0.049
E64.8 Sequelae of other nutritional deficiencies
0.000 0.950 0.049
E64.3 Sequelae of rickets
0.000 0.950 0.049
E64.2 Sequelae of vitamin C deficiency
0.000 0.950 0.049
E64.1 Sequelae of vitamin A deficiency
0.000 0.950 0.049
E64.0 Sequelae of protein-energy malnutrition
0.000 0.950 0.049
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.950 0.050
K90-K93 Other diseases of the digestive system
0.000 0.950 0.050
C93.9 Monocytic leukaemia, unspecified
0.000 0.951 0.049
C93.7 Other monocytic leukaemia
0.000 0.951 0.049
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.951 0.049
C93.2 Subacute monocytic leukaemia
0.000 0.951 0.049
C93.0 Acute monocytic leukaemia
0.000 0.951 0.049
C95.9 Leukaemia, unspecified
0.000 0.951 0.049
E61.9 Deficiency of nutrient element, unspecified
0.000 0.952 0.048
E61.8 Deficiency of other specified nutrient elements
0.000 0.952 0.048
E61.7 Deficiency of multiple nutrient elements
0.000 0.952 0.048
E61.6 Vanadium deficiency
0.000 0.952 0.048
E61.5 Molybdenum deficiency
0.000 0.952 0.048
E61.4 Chromium deficiency
0.000 0.952 0.048
E61.3 Manganese deficiency
0.000 0.952 0.048
E61.0 Copper deficiency
0.000 0.952 0.048
C82.4 Follicular lymphoma grade IIIb
0.000 0.952 0.048
C82.0 Small cleaved cell, follicular
0.000 0.952 0.048
C94.7 Other specified leukaemias
0.000 0.952 0.047
C94.5 Acute myelofibrosis
0.000 0.952 0.047
C94.4 Acute panmyelosis
0.000 0.952 0.047
C94.3 Mast cell leukaemia
0.000 0.952 0.047
C94.2 Acute megakaryoblastic leukaemia
0.000 0.952 0.047
C94.1 Chronic erythraemia
0.000 0.952 0.047
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.952 0.047
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.953 0.047
C88.7 Other malignant immunoproliferative diseases
0.000 0.953 0.047
C88.3 Immunoproliferative small intestinal disease
0.000 0.953 0.047
C88.2 Gamma heavy chain disease
0.000 0.953 0.047
C88.1 Alpha heavy chain disease
0.000 0.953 0.047
C93.1 Chronic monocytic leukaemia
0.000 0.953 0.047
E22.1 Hyperprolactinaemia
0.000 0.953 0.047
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.953 0.047
G63.2 Diabetic polyneuropathy
0.047 0.953 0.000
C95.7 Other leukaemia of unspecified cell type
0.000 0.953 0.047
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.953 0.047
E53 Deficiency of other B group vitamins
0.000 0.954 0.046
E55 Vitamin D deficiency
0.000 0.954 0.045
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.955 0.045
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.956 0.044
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.956 0.044
C92.3 Myeloid sarcoma
0.000 0.956 0.044
C92.2 Subacute myeloid leukaemia
0.000 0.956 0.044
E04.8 Other specified non-toxic goitre
0.000 0.957 0.043
C92.5 Acute myelomonocytic leukaemia
0.000 0.957 0.043
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.957 0.043
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.958 0.042
E83 Disorders of mineral metabolism
0.039 0.958 0.002
E27 Other disorders of adrenal gland
0.000 0.958 0.042
E14.9 Without complications
0.000 0.958 0.042
C84.4 Peripheral T-cell lymphoma
0.000 0.959 0.040
M35.3 Polymyalgia rheumatica
0.000 0.960 0.040
E61.1 Iron deficiency
0.000 0.960 0.040
C95.0 Acute leukaemia of unspecified cell type
0.000 0.960 0.039
E65 Localised adiposity
0.000 0.961 0.039
C83.0 Small cell (diffuse)
0.000 0.963 0.037
C92.9 Myeloid leukaemia, unspecified
0.000 0.963 0.037
C91 Lymphoid leukaemia
0.000 0.963 0.037
E67.8 Other specified hyperalimentation
0.000 0.964 0.036
E67.3 Hypervitaminosis D
0.000 0.964 0.036
E67.2 Megavitamin-B6 syndrome
0.000 0.964 0.036
E67.1 Hypercarotenaemia
0.000 0.964 0.036
E67.0 Hypervitaminosis A
0.000 0.964 0.036
E04.0 Non-toxic diffuse goitre
0.000 0.964 0.036
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.964 0.036
E34.9 Endocrine disorder, unspecified
0.001 0.964 0.035
E22.0 Acromegaly and pituitary gigantism
0.000 0.965 0.034
C92.4 Acute promyelocytic leukaemia
0.000 0.966 0.034
N05.2 Diffuse membranous glomerulonephritis
0.000 0.966 0.034
E34.0 Carcinoid syndrome
0.001 0.966 0.033
N05.9 Unspecified
0.000 0.967 0.033
E53.1 Pyridoxine deficiency
0.000 0.967 0.033
E53.0 Riboflavin deficiency
0.000 0.967 0.033
C92.7 Other myeloid leukaemia
0.000 0.967 0.033
N05 Unspecified nephritic syndrome
0.000 0.967 0.033
E55.0 Rickets, active
0.000 0.967 0.033
C91.9 Lymphoid leukaemia, unspecified
0.000 0.968 0.031
E83.9 Disorder of mineral metabolism, unspecified
0.029 0.969 0.002
E83.8 Other disorders of mineral metabolism
0.028 0.970 0.002
E83.2 Disorders of zinc metabolism
0.028 0.970 0.002
E83.0 Disorders of copper metabolism
0.028 0.970 0.002
E27.5 Adrenomedullary hyperfunction
0.000 0.970 0.030
E27.0 Other adrenocortical overactivity
0.000 0.970 0.030
E53.9 Vitamin B deficiency, unspecified
0.000 0.970 0.029
E27.1 Primary adrenocortical insufficiency
0.000 0.971 0.029
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.971 0.029
N05.1 Focal and segmental glomerular lesions
0.000 0.971 0.029
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.971 0.028
E27.9 Disorder of adrenal gland, unspecified
0.000 0.972 0.028
K60.1 Chronic anal fissure
0.000 0.972 0.028
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.973 0.027
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.973 0.027
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.973 0.026
C91.7 Other lymphoid leukaemia
0.000 0.973 0.026
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.973 0.026
C91.3 Prolymphocytic leukaemia
0.000 0.973 0.026
C91.2 Subacute lymphocytic leukaemia
0.000 0.973 0.026
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.974 0.026
K93.1 Megacolon in Chagas' disease
0.000 0.974 0.026
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.974 0.026
C91.5 Adult T-cell leukaemia
0.000 0.974 0.025
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.975 0.025
S72.30 Fracture of shaft of femur (closed)
0.025 0.975 0.000
N05.6 Dense deposit disease
0.000 0.976 0.024
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.976 0.024
N05.0 Minor glomerular abnormality
0.000 0.976 0.024
E27.2 Addisonian crisis
0.000 0.977 0.023
S72.3 Fracture of shaft of femur
0.022 0.978 0.000
C90.1 Plasma cell leukaemia
0.001 0.978 0.022
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.978 0.022
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.978 0.022
C91.4 Hairy-cell leukaemia
0.000 0.978 0.022
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.022 0.978 0.000
N05.8 Other
0.000 0.979 0.021
G63 Polyneuropathy in diseases classified elsewhere
0.021 0.979 0.000
S72 Fracture of femur
0.020 0.980 0.000
C90.3 Solitary plasmacytoma
0.001 0.980 0.019
E83.3 Disorders of phosphorus metabolism
0.018 0.981 0.002
C91.0 Acute lymphoblastic leukaemia
0.000 0.981 0.019

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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