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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2524054
log Bayes Factor = 252.073
Chromosome 6   position 31,252,396  (GRCh37) Explore rs2524054 on Ensembl!
Variant rs2524054 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
R31 Unspecified haematuria
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
D69.6 Thrombocytopenia, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
# Top node
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.000 1.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.000 1.000
E27.1 Primary adrenocortical insufficiency
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.001 0.999
Chapter VI Diseases of the nervous system
0.000 0.001 0.999
L40 Psoriasis
0.998 0.002 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.002 0.998
H36.0 Diabetic retinopathy
0.000 0.003 0.997
H36 Retinal disorders in diseases classified elsewhere
0.000 0.004 0.996
H30-H36 Disorders of choroid and retina
0.000 0.004 0.996
Chapter I Certain infectious and parasitic diseases
0.000 0.004 0.996
E50-E64 Other nutritional deficiencies
0.000 0.004 0.996
E27 Other disorders of adrenal gland
0.000 0.004 0.996
Chapter VII Diseases of the eye and adnexa
0.000 0.004 0.996
M45.X9 Ankylosing spondylitis (Site unspecified)
0.995 0.005 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.005 0.995
D86 Sarcoidosis
0.000 0.005 0.995
K90 Intestinal malabsorption
0.000 0.005 0.995
D51 Vitamin B12 deficiency anaemia
0.000 0.006 0.994
E53 Deficiency of other B group vitamins
0.000 0.006 0.994
D50 Iron deficiency anaemia
0.000 0.007 0.993
D86.9 Sarcoidosis, unspecified
0.000 0.007 0.993
E53.8 Deficiency of other specified B group vitamins
0.000 0.009 0.991
E10.1 With ketoacidosis
0.000 0.009 0.991
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.013 0.987
D50.9 Iron deficiency anaemia, unspecified
0.000 0.015 0.985
E14 Unspecified diabetes mellitus
0.000 0.016 0.984
E10.2 With renal complications
0.000 0.016 0.984
L40.5 Arthropathic psoriasis
0.984 0.016 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.016 0.984
E14.3 With ophthalmic complications
0.000 0.022 0.978
K90-K93 Other diseases of the digestive system
0.000 0.024 0.976
Chapter XI Diseases of the digestive system
0.000 0.024 0.976
B35-B49 Mycoses
0.000 0.025 0.975
B07 Viral warts
0.000 0.026 0.974
R30-R39 Symptoms and signs involving the urinary system
0.973 0.027 0.000
K70-K77 Diseases of liver
0.000 0.029 0.971
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.029 0.971
B37 Candidiasis
0.000 0.030 0.970
R30 Pain associated with micturition
0.969 0.031 0.000
R30.0 Dysuria
0.968 0.032 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.032 0.968
I25 Chronic ischaemic heart disease
0.968 0.032 0.000
H34 Retinal vascular occlusions
0.000 0.033 0.967
B37.8 Candidiasis of other sites
0.000 0.033 0.967
K75 Other inflammatory liver diseases
0.000 0.034 0.966
K75.4 Autoimmune hepatitis
0.000 0.038 0.962
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.040 0.960
I20-I25 Ischaemic heart diseases
0.957 0.043 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.046 0.954
I25.1 Atherosclerotic heart disease
0.954 0.046 0.000
I20 Angina pectoris
0.938 0.062 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.064 0.936
B37.9 Candidiasis, unspecified
0.000 0.067 0.933
E16 Other disorders of pancreatic internal secretion
0.000 0.068 0.932
I25.2 Old myocardial infarction
0.925 0.075 0.000
B25-B34 Other viral diseases
0.000 0.079 0.921
E06 Thyroiditis
0.000 0.079 0.921
K70 Alcoholic liver disease
0.000 0.082 0.918
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.083 0.917
G00 Bacterial meningitis, not elsewhere classified
0.000 0.085 0.915
E16.2 Hypoglycaemia, unspecified
0.000 0.086 0.914
D80 Immunodeficiency with predominantly antibody defects
0.000 0.089 0.911
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.090 0.910
L40.8 Other psoriasis
0.907 0.093 0.000
G30-G32 Other degenerative diseases of the nervous system
0.000 0.095 0.905
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.095 0.905
M45 Ankylosing spondylitis
0.902 0.097 0.001
K90.9 Intestinal malabsorption, unspecified
0.000 0.097 0.903
K73 Chronic hepatitis, not elsewhere classified
0.000 0.097 0.903
I20.0 Unstable angina
0.902 0.098 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.101 0.899
H34.8 Other retinal vascular occlusions
0.000 0.106 0.894
E06.3 Autoimmune thyroiditis
0.000 0.107 0.893
H16 Keratitis
0.000 0.107 0.893
B25 Cytomegaloviral disease
0.000 0.108 0.892
L40.0 Psoriasis vulgaris
0.891 0.109 0.000
R39 Other symptoms and signs involving the urinary system
0.888 0.112 0.000
D60-D64 Aplastic and other anaemias
0.000 0.113 0.887
K70.9 Alcoholic liver disease, unspecified
0.000 0.115 0.885
R35 Polyuria
0.883 0.117 0.000
H34.2 Other retinal artery occlusions
0.000 0.121 0.879
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.124 0.876
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.124 0.876
D69.4 Other primary thrombocytopenia
0.000 0.125 0.875
I20.9 Angina pectoris, unspecified
0.873 0.127 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.871 0.129 0.000
I25.5 Ischaemic cardiomyopathy
0.870 0.130 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.132 0.868
I22 Subsequent myocardial infarction
0.867 0.133 0.000
D69.5 Secondary thrombocytopenia
0.000 0.136 0.864
D55-D59 Haemolytic anaemias
0.000 0.137 0.863
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.137 0.863
I25.8 Other forms of chronic ischaemic heart disease
0.862 0.138 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.139 0.861
I25.9 Chronic ischaemic heart disease, unspecified
0.861 0.139 0.000
B25.9 Cytomegaloviral disease, unspecified
0.000 0.139 0.861
H30 Chorioretinal inflammation
0.000 0.142 0.858
H18 Other disorders of cornea
0.000 0.142 0.858
E10.4 With neurological complications
0.000 0.143 0.857
D72 Other disorders of white blood cells
0.000 0.146 0.854
I22.1 Subsequent myocardial infarction of inferior wall
0.854 0.146 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.146 0.853
H16.0 Corneal ulcer
0.000 0.147 0.853
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.147 0.853
D69.2 Other nonthrombocytopenic purpura
0.000 0.148 0.852
E20 Hypoparathyroidism
0.000 0.149 0.851
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.849 0.151 0.000
A63.0 Anogenital (venereal) warts
0.000 0.151 0.849
K75.8 Other specified inflammatory liver diseases
0.000 0.154 0.846
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.155 0.845
E55 Vitamin D deficiency
0.000 0.155 0.845
L40.4 Guttate psoriasis
0.844 0.156 0.000
H06.2 Dysthyroid exophthalmos
0.000 0.158 0.842
D50.1 Sideropenic dysphagia
0.000 0.160 0.840
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.161 0.839
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.162 0.837
H05 Disorders of orbit
0.000 0.163 0.837
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.163 0.837
D70 Agranulocytosis
0.000 0.168 0.832
D61 Other aplastic anaemias
0.000 0.170 0.830
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.170 0.830
B44 Aspergillosis
0.000 0.171 0.829
D64 Other anaemias
0.000 0.171 0.829
B01 Varicella [chickenpox]
0.000 0.172 0.828
D86.3 Sarcoidosis of skin
0.000 0.172 0.828
E27.2 Addisonian crisis
0.000 0.173 0.827
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.174 0.826
E31 Polyglandular dysfunction
0.000 0.176 0.824
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.177 0.823
D53 Other nutritional anaemias
0.000 0.178 0.822
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.179 0.821
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.180 0.820
G37 Other demyelinating diseases of central nervous system
0.000 0.182 0.818
E10.7 With multiple complications
0.000 0.186 0.814
H18.6 Keratoconus
0.000 0.190 0.810
H31 Other disorders of choroid
0.000 0.194 0.806
D59 Acquired haemolytic anaemia
0.000 0.195 0.805
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.196 0.804
H46 Optic neuritis
0.000 0.198 0.802
G00.9 Bacterial meningitis, unspecified
0.000 0.200 0.800
E03.8 Other specified hypothyroidism
0.000 0.201 0.799
D69.8 Other specified haemorrhagic conditions
0.000 0.202 0.798
E14.2 Withrenal complications
0.000 0.203 0.797
I23 Certain current complications following acute myocardial infarction
0.795 0.205 0.000
A30-A49 Other bacterial diseases
0.000 0.206 0.794
G00.1 Pneumococcal meningitis
0.000 0.208 0.792
D61.9 Aplastic anaemia, unspecified
0.000 0.208 0.792
K50-K52 Noninfective enteritis and colitis
0.000 0.212 0.788
D83 Common variable immunodeficiency
0.000 0.213 0.787
D84 Other immunodeficiencies
0.000 0.216 0.784
H18.1 Bullous keratopathy
0.000 0.219 0.781
B27 Infectious mononucleosis
0.000 0.221 0.779
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.222 0.778
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.000 0.224 0.776
I21 Acute myocardial infarction
0.776 0.224 0.000
D72.8 Other specified disorders of white blood cells
0.000 0.225 0.775
M35 Other systemic involvement of connective tissue
0.000 0.227 0.773
B37.2 Candidiasis of skin and nail
0.000 0.229 0.771
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.231 0.769
H05.2 Exophthalmic conditions
0.000 0.236 0.764
R34 Anuria and oliguria
0.764 0.236 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.238 0.762
H16.9 Keratitis, unspecified
0.000 0.238 0.762
L40.1 Generalised pustular psoriasis
0.759 0.241 0.000
D52 Folate deficiency anaemia
0.000 0.241 0.759
I25.3 Aneurysm of heart
0.757 0.243 0.000
G00.2 Streptococcal meningitis
0.000 0.244 0.756
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.244 0.756
E05.8 Other thyrotoxicosis
0.000 0.244 0.756
D66 Hereditary factor VIII deficiency
0.000 0.245 0.755
D86.1 Sarcoidosis of lymph nodes
0.000 0.247 0.753
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.251 0.749
B15-B19 Viral hepatitis
0.000 0.252 0.748
E20.9 Hypoparathyroidism, unspecified
0.000 0.252 0.748
E51 Thiamine deficiency
0.000 0.253 0.747
E14.6 With other specified complications
0.000 0.253 0.747
H18.3 Changes in corneal membranes
0.000 0.257 0.743
M45.X2 Ankylosing spondylitis (Cervical region)
0.742 0.257 0.000
E10.8 With unspecified complications
0.000 0.258 0.742
G70-G73 Diseases of myoneural junction and muscle
0.000 0.260 0.740
K73.9 Chronic hepatitis, unspecified
0.000 0.260 0.740
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.263 0.737
E55.9 Vitamin D deficiency, unspecified
0.000 0.264 0.736
I25.0 Atherosclerotic cardiovascular disease, so described
0.736 0.264 0.000
H30.9 Chorioretinal inflammation, unspecified
0.000 0.266 0.734
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.267 0.733
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.268 0.732
E14.8 With unspecified complications
0.000 0.269 0.730
D64.8 Other specified anaemias
0.000 0.270 0.730
B25.0 Cytomegaloviral pneumonitis
0.000 0.275 0.725
H34.9 Retinal vascular occlusion, unspecified
0.000 0.276 0.724
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.276 0.724
D89.1 Cryoglobulinaemia
0.000 0.278 0.721
E63 Other nutritional deficiencies
0.000 0.279 0.721
E14.5 With peripheral circulatory complications
0.000 0.279 0.720
I21.9 Acute myocardial infarction, unspecified
0.720 0.280 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.281 0.719
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
B44.9 Aspergillosis, unspecified
0.000 0.283 0.717
D81 Combined immunodeficiencies
0.000 0.283 0.717
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.715 0.284 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.285 0.714
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.286 0.714
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.286 0.714
A75-A79 Rickettsioses
0.000 0.286 0.714
A70-A74 Other diseases caused by chlamydiae
0.000 0.286 0.714
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.286 0.714
E50 Vitamin A deficiency
0.000 0.286 0.714
E60 Dietary zinc deficiency
0.000 0.286 0.714
E59 Dietary selenium deficiency
0.000 0.286 0.714
E52 Niacin deficiency [pellagra]
0.000 0.286 0.714
E14.1 With ketoacidosis
0.000 0.286 0.714
E27.5 Adrenomedullary hyperfunction
0.000 0.286 0.714
E27.0 Other adrenocortical overactivity
0.000 0.286 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.713
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.713
K90.3 Pancreatic steatorrhoea
0.000 0.287 0.713
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.287 0.713
K90.1 Tropical sprue
0.000 0.287 0.713
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.287 0.713
D51.2 Transcobalamin II deficiency
0.000 0.287 0.713
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.287 0.713
E53.1 Pyridoxine deficiency
0.000 0.287 0.713
E53.0 Riboflavin deficiency
0.000 0.287 0.713
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.289 0.711
H16.8 Other keratitis
0.000 0.289 0.711
E10.0 With coma
0.000 0.290 0.710
G31.2 Degeneration of nervous system due to alcohol
0.000 0.291 0.709
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.291 0.708
D64.9 Anaemia, unspecified
0.000 0.292 0.708
E14.7 With multiple complications
0.000 0.294 0.706
E14.0 With coma
0.000 0.294 0.706
B06 Rubella [German measles]
0.000 0.294 0.705
B05 Measles
0.000 0.294 0.705
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.000 0.294 0.705
B04 Monkeypox
0.000 0.294 0.705
B03 Smallpox
0.000 0.294 0.705
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.295 0.705
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.296 0.704
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.298 0.702
E31.0 Autoimmune polyglandular failure
0.000 0.298 0.702
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.000 0.299 0.701
K90.8 Other intestinal malabsorption
0.000 0.299 0.701
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.300 0.700
B48 Other mycoses, not elsewhere classified
0.000 0.301 0.699
B46 Zygomycosis
0.000 0.301 0.699
B45 Cryptococcosis
0.000 0.301 0.699
B43 Chromomycosis and phaeomycotic abscess
0.000 0.301 0.699
B42 Sporotrichosis
0.000 0.301 0.699
B41 Paracoccidioidomycosis
0.000 0.301 0.699
B40 Blastomycosis
0.000 0.301 0.699
B39 Histoplasmosis
0.000 0.301 0.699
B38 Coccidioidomycosis
0.000 0.301 0.699
G36 Other acute disseminated demyelination
0.000 0.301 0.699
B36 Other superficial mycoses
0.000 0.304 0.696
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.304 0.696
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.304 0.695
B37.6 Candidal endocarditis
0.000 0.305 0.695
B37.5 Candidal meningitis
0.000 0.305 0.695
B01.9 Varicella without complications
0.000 0.305 0.695
K51 Ulcerative colitis
0.000 0.305 0.695
D69.9 Haemorrhagic condition, unspecified
0.000 0.306 0.694
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.306 0.694
E34 Other endocrine disorders
0.000 0.306 0.693
K52 Other non-infective gastro-enteritis and colitis
0.000 0.307 0.693
H16.1 Other superficial keratitis without conjunctivitis
0.000 0.307 0.693
H34.0 Transient retinal artery occlusion
0.000 0.307 0.693
K75.2 Nonspecific reactive hepatitis
0.000 0.308 0.692
K75.1 Phlebitis of portal vein
0.000 0.308 0.692
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.308 0.692
H05.0 Acute inflammation of orbit
0.000 0.308 0.692
E15 Nondiabetic hypoglycaemic coma
0.000 0.312 0.688
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.312 0.688
E06.9 Thyroiditis, unspecified
0.000 0.313 0.687
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.314 0.685
D89.3 Immune reconstitution syndrome
0.000 0.316 0.684
A20-A28 Certain zoonotic bacterial diseases
0.000 0.316 0.684
H34.1 Central retinal artery occlusion
0.000 0.316 0.684
B37.7 Candidal septicaemia
0.000 0.318 0.682
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.681 0.318 0.001
B00 Herpesviral [herpes simplex] infections
0.000 0.318 0.682
D53.9 Nutritional anaemia, unspecified
0.000 0.319 0.681
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.320 0.680
E03.1 Congenital hypothyroidism without goitre
0.000 0.320 0.680
E10.5 With peripheral circulatory complications
0.000 0.322 0.678
E14.4 With neurological complications
0.000 0.323 0.677
I24 Other acute ischaemic heart diseases
0.677 0.323 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.324 0.676
A65-A69 Other spirochaetal diseases
0.000 0.324 0.676
M35.7 Hypermobility syndrome
0.000 0.324 0.676
D59.1 Other autoimmune haemolytic anaemias
0.000 0.326 0.674
B16 Acute hepatitis B
0.000 0.327 0.673
D72.1 Eosinophilia
0.000 0.327 0.673
H31.0 Chorioretinal scars
0.000 0.328 0.672
H10-H13 Disorders of conjunctiva
0.000 0.328 0.671
D74 Methaemoglobinaemia
0.000 0.329 0.671
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.329 0.671
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.329 0.671
B27.9 Infectious mononucleosis, unspecified
0.000 0.329 0.671
R30.1 Vesical tenesmus
0.670 0.330 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.331 0.668
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.332 0.668
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.332 0.668
E16.4 Abnormal secretion of gastrin
0.000 0.332 0.668
E16.3 Increased secretion of glucagon
0.000 0.332 0.668
K77 Liver disorders in diseases classified elsewhere
0.000 0.335 0.665
E07 Other disorders of thyroid
0.000 0.335 0.665
E58 Dietary calcium deficiency
0.000 0.335 0.665
I20.8 Other forms of angina pectoris
0.665 0.335 0.000
D76.3 Other histiocytosis syndromes
0.000 0.336 0.664
H18.5 Hereditary corneal dystrophies
0.000 0.336 0.664
H30.2 Posterior cyclitis
0.000 0.336 0.664
G00.8 Other bacterial meningitis
0.000 0.337 0.663
B37.4 Candidiasis of other urogenital sites
0.000 0.338 0.662
M35.3 Polymyalgia rheumatica
0.000 0.338 0.662
B26 Mumps
0.000 0.339 0.660
E06.4 Drug-induced thyroiditis
0.000 0.339 0.660
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.339 0.660
E06.0 Acute thyroiditis
0.000 0.339 0.660
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.340 0.660
I23.8 Other current complications following acute myocardial infarction
0.659 0.341 0.000
H16.3 Interstitial and deep keratitis
0.000 0.341 0.659
E54 Ascorbic acid deficiency
0.000 0.341 0.658
A59 Trichomoniasis
0.000 0.342 0.658
A56 Other sexually transmitted chlamydial diseases
0.000 0.342 0.658
A54 Gonococcal infection
0.000 0.342 0.658
A53 Other and unspecified syphilis
0.000 0.342 0.658
A51 Early syphilis
0.000 0.342 0.658
A50 Congenital syphilis
0.000 0.342 0.658
A64 Unspecified sexually transmitted disease
0.000 0.342 0.658
A58 Granuloma inguinale
0.000 0.342 0.658
A57 Chancroid
0.000 0.342 0.658
A55 Chlamydial lymphogranuloma (venereum)
0.000 0.342 0.658
G00.0 Haemophilus meningitis
0.000 0.344 0.656
E28 Ovarian dysfunction
0.000 0.344 0.655
G62 Other polyneuropathies
0.000 0.346 0.654
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.347 0.653
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.347 0.653
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.347 0.653
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.347 0.653
B44.1 Other pulmonary aspergillosis
0.000 0.349 0.651
A40 Streptococcal septicaemia
0.000 0.351 0.649
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.351 0.649
K70.3 Alcoholic cirrhosis of liver
0.000 0.351 0.649
E40-E46 Malnutrition
0.000 0.352 0.648
L40-L45 Papulosquamous disorders
0.525 0.352 0.123
G31.0 Circumscribed brain atrophy
0.000 0.352 0.648
D75 Other diseases of blood and blood-forming organs
0.000 0.352 0.647
A41 Other septicaemia
0.000 0.353 0.647
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.647 0.353 0.001
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.647 0.353 0.001
M45.X4 Ankylosing spondylitis (Thoracic region)
0.647 0.353 0.001
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.647 0.353 0.001
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.647 0.353 0.001
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.353 0.647
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.353 0.647
M45.X6 Ankylosing spondylitis (Lumbar region)
0.646 0.353 0.001
E56 Other vitamin deficiencies
0.000 0.354 0.646
G06.0 Intracranial abscess and granuloma
0.000 0.354 0.646
E22 Hyperfunction of pituitary gland
0.000 0.355 0.645
K65-K67 Diseases of peritoneum
0.000 0.355 0.645
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.000 0.355 0.645
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.000 0.355 0.645
D82 Immunodeficiency associated with other major defects
0.000 0.355 0.644
B01.2 Varicella pneumonia
0.000 0.356 0.644
A48 Other bacterial diseases, not elsewhere classified
0.000 0.357 0.643
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.357 0.643
E27.8 Other specified disorders of adrenal gland
0.000 0.357 0.643
G62.9 Polyneuropathy, unspecified
0.000 0.359 0.641
B25.2 Cytomegaloviral pancreatitis
0.000 0.361 0.639
B25.1 Cytomegaloviral hepatitis
0.000 0.361 0.639
D69.1 Qualitative platelet defects
0.000 0.361 0.639
H05.4 Enophthalmos
0.000 0.361 0.639
L50-L54 Urticaria and erythema
0.000 0.361 0.639
E24 Cushing's syndrome
0.000 0.362 0.638
H18.0 Corneal pigmentations and deposits
0.000 0.363 0.637
R39.2 Extrarenal uraemia
0.637 0.363 0.000
B47 Mycetoma
0.000 0.364 0.636
D83.9 Common variable immunodeficiency, unspecified
0.000 0.366 0.634
B30 Viral conjunctivitis
0.000 0.366 0.634
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.367 0.633
H05.8 Other disorders of orbit
0.000 0.367 0.633
H31.9 Disorder of choroid, unspecified
0.000 0.369 0.630
I25.4 Coronary artery aneurysm
0.628 0.372 0.000
E25 Adrenogenital disorders
0.000 0.372 0.628
H16.2 Keratoconjunctivitis
0.000 0.372 0.628
B08.1 Molluscum contagiosum
0.000 0.373 0.627
L10-L14 Bullous disorders
0.000 0.373 0.627
D58 Other hereditary haemolytic anaemias
0.000 0.374 0.626
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.374 0.626
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.374 0.626
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.375 0.625
H18.7 Other corneal deformities
0.000 0.376 0.624
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.376 0.624
B25.8 Other cytomegaloviral diseases
0.000 0.376 0.623
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.377 0.623
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.377 0.623
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.377 0.623
I25.6 Silent myocardial ischaemia
0.622 0.377 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.378 0.622
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.378 0.622
A46 Erysipelas
0.000 0.379 0.621
K70.1 Alcoholic hepatitis
0.000 0.379 0.621
D55 Anaemia due to enzyme disorders
0.000 0.381 0.619
A60 Anogenital herpesviral [herpes simplex] infections
0.000 0.381 0.619
B16.9 Acute hepatitis B without delta-agent and without hepatic coma
0.000 0.382 0.618
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.382 0.618
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.000 0.382 0.618
H30.8 Other chorioretinal inflammations
0.000 0.385 0.615
H30.1 Disseminated chorioretinal inflammation
0.000 0.385 0.615
H30.0 Focal chorioretinal inflammation
0.000 0.385 0.615
D64.3 Other sideroblastic anaemias
0.000 0.385 0.615
A63.8 Other specified predominantly sexually transmitted diseases
0.000 0.385 0.615
D64.0 Hereditary sideroblastic anaemia
0.000 0.385 0.615
A39 Meningococcal infection
0.000 0.386 0.613
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.000 0.387 0.613
D72.9 Disorder of white blood cells, unspecified
0.000 0.388 0.612
D72.0 Genetic anomalies of leukocytes
0.000 0.388 0.612
E20.8 Other hypoparathyroidism
0.000 0.388 0.612
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.388 0.612
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.389 0.611
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.389 0.611
G03 Meningitis due to other and unspecified causes
0.000 0.389 0.611
H31.8 Other specified disorders of choroid
0.000 0.389 0.610
E20.1 Pseudohypoparathyroidism
0.000 0.390 0.610
E20.0 Idiopathic hypoparathyroidism
0.000 0.390 0.610
K70.0 Alcoholic fatty liver
0.000 0.390 0.610
K75.0 Abscess of liver
0.000 0.391 0.609
D84.9 Immunodeficiency, unspecified
0.000 0.393 0.607
A52 Late syphilis
0.000 0.393 0.606
H16.4 Corneal neovascularisation
0.000 0.394 0.606
E55.0 Rickets, active
0.000 0.394 0.605
G00.3 Staphylococcal meningitis
0.000 0.395 0.605
B33 Other viral diseases, not elsewhere classified
0.000 0.396 0.604
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.603 0.397 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.397 0.603
D84.1 Defects in the complement system
0.000 0.397 0.603
D61.0 Constitutional aplastic anaemia
0.000 0.399 0.601
D67 Hereditary factor IX deficiency
0.000 0.399 0.601
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.399 0.600
H05.3 Deformity of orbit
0.000 0.399 0.600
L40.3 Pustulosis palmaris et plantaris
0.600 0.400 0.000
A40.8 Other streptococcal septicaemia
0.000 0.400 0.600
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.400 0.600
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.401 0.599
R39.0 Extravasation of urine
0.598 0.402 0.000
B01.0 Varicella meningitis
0.000 0.402 0.598
D57 Sickle-cell disorders
0.000 0.404 0.596
K70.4 Alcoholic hepatic failure
0.000 0.405 0.595
H02 Other disorders of eyelid
0.000 0.405 0.595
D86.0 Sarcoidosis of lung
0.000 0.405 0.595
D61.8 Other specified aplastic anaemias
0.000 0.405 0.595
D61.3 Idiopathic aplastic anaemia
0.000 0.405 0.595
D61.2 Aplastic anaemia due to other external agents
0.000 0.405 0.595
B44.7 Disseminated aspergillosis
0.000 0.405 0.595
B44.2 Tonsillar aspergillosis
0.000 0.405 0.595
B44.0 Invasive pulmonary aspergillosis
0.000 0.405 0.595
D64.4 Congenital dyserythropoietic anaemia
0.000 0.406 0.594
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.406 0.594
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.406 0.594
B01.1 Varicella encephalitis
0.000 0.406 0.594
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.408 0.591
E31.9 Polyglandular dysfunction, unspecified
0.000 0.409 0.591
E31.8 Other polyglandular dysfunction
0.000 0.409 0.591
E31.1 Polyglandular hyperfunction
0.000 0.409 0.591
K51.5 Mucosal proctocolitis
0.000 0.410 0.590

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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