TreeWAS – Variant ID: rs3134605

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
N18 Chronic renal failure	1.000	0.000	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	1.000	0.000	0.000
N00-N08 Glomerular diseases	1.000	0.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	1.000	0.000	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
G50-G59 Nerve, nerve root and plexus disorders	1.000	0.000	0.000
L40-L45 Papulosquamous disorders	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000	0.000
N17-N19 Renal failure	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
E20-E35 Disorders of other endocrine glands	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.999	0.001	0.000
G56 Mononeuropathies of upper limb	0.999	0.001	0.000
K70-K77 Diseases of liver	0.999	0.001	0.000
G56.0 Carpal tunnel syndrome	0.999	0.001	0.000
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
K75 Other inflammatory liver diseases	0.999	0.001	0.000
E16.2 Hypoglycaemia, unspecified	0.999	0.001	0.000
N18.3 Chronic kidney disease, stage 3	0.998	0.002	0.000
Chapter II Neoplasms	0.998	0.002	0.000
N04 Nephrotic syndrome	0.998	0.002	0.000
E27 Other disorders of adrenal gland	0.997	0.003	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.997	0.003	0.000
Chapter VI Diseases of the nervous system	0.997	0.003	0.000
E27.1 Primary adrenocortical insufficiency	0.997	0.003	0.000
E14.9 Without complications	0.997	0.003	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.996	0.004	0.000
K29 Gastritis and duodenitis	0.995	0.005	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.995	0.005	0.000
N04.9 Unspecified	0.993	0.007	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.993	0.007	0.000
K31 Other diseases of stomach and duodenum	0.993	0.007	0.000
K75.4 Autoimmune hepatitis	0.993	0.007	0.000
E70-E90 Metabolic disorders	0.993	0.007	0.000
N18.9 Chronic renal failure, unspecified	0.992	0.008	0.000
K31.8 Other specified diseases of stomach and duodenum	0.992	0.008	0.000
G51 Facial nerve disorders	0.992	0.008	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.992	0.008	0.000
E14.3 With ophthalmic complications	0.992	0.008	0.000
K75.8 Other specified inflammatory liver diseases	0.992	0.008	0.000
K29.5 Chronic gastritis, unspecified	0.991	0.009	0.000
E89.0 Postprocedural hypothyroidism	0.991	0.009	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.988	0.012	0.000
N05 Unspecified nephritic syndrome	0.987	0.013	0.000
C85.1 B-cell lymphoma, unspecified	0.986	0.014	0.000
C83.3 Large cell (diffuse)	0.985	0.015	0.000
K29.8 Duodenitis	0.985	0.015	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.985	0.015	0.000
E10.2 With renal complications	0.979	0.021	0.000
C15-C26 Malignant neoplasms of digestive organs	0.978	0.022	0.000
L40.0 Psoriasis vulgaris	0.976	0.024	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.975	0.025	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.975	0.025	0.000
K73 Chronic hepatitis, not elsewhere classified	0.975	0.025	0.000
N18.2 Chronic kidney disease, stage 2	0.975	0.025	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.975	0.025	0.000
Chapter IX Diseases of the circulatory system	0.972	0.028	0.000
Chapter I Certain infectious and parasitic diseases	0.969	0.031	0.000
G51.0 Bell's palsy	0.968	0.032	0.000
D70 Agranulocytosis	0.966	0.034	0.000
K90-K93 Other diseases of the digestive system	0.964	0.036	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.963	0.037	0.000
E50-E64 Other nutritional deficiencies	0.963	0.037	0.000
L10-L14 Bullous disorders	0.963	0.037	0.000
K90 Intestinal malabsorption	0.962	0.038	0.000
L50-L54 Urticaria and erythema	0.961	0.039	0.000
K90.9 Intestinal malabsorption, unspecified	0.958	0.042	0.000
G51.9 Disorder of facial nerve, unspecified	0.957	0.043	0.000
C34 Malignant neoplasm of bronchus and lung	0.955	0.045	0.000
E11.3 With ophthalmic complications	0.955	0.045	0.000
D80-D89 Certain disorders involving the immune mechanism	0.955	0.045	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.955	0.045	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.955	0.045	0.000
E11.1 With ketoacidosis	0.950	0.050	0.000
K29.7 Gastritis, unspecified	0.948	0.052	0.000
C20 Malignant neoplasm of rectum	0.947	0.053	0.000
C91 Lymphoid leukaemia	0.943	0.057	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.942	0.058	0.000
I74 Arterial embolism and thrombosis	0.940	0.060	0.000
E10.4 With neurological complications	0.938	0.062	0.000
N05.2 Diffuse membranous glomerulonephritis	0.938	0.062	0.000
Q50-Q56 Congenital malformations of genital organs	0.936	0.064	0.000
L13 Other bullous disorders	0.931	0.069	0.000
E11.5 With peripheral circulatory complications	0.926	0.074	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.925	0.075	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.923	0.077	0.000
K50-K52 Noninfective enteritis and colitis	0.917	0.077	0.007
C34.3 Lower lobe, bronchus or lung	0.922	0.078	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.922	0.078	0.000
I77 Other disorders of arteries and arterioles	0.922	0.078	0.000
E11.2 With renal complications	0.914	0.086	0.000
K52 Other non-infective gastro-enteritis and colitis	0.911	0.087	0.002
K73.9 Chronic hepatitis, unspecified	0.913	0.087	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.909	0.091	0.000
E14.8 With unspecified complications	0.909	0.091	0.000
L13.0 Dermatitis herpetiformis	0.909	0.091	0.000
C18 Malignant neoplasm of colon	0.908	0.092	0.000
I73 Other peripheral vascular diseases	0.907	0.093	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.906	0.094	0.000
L40.1 Generalised pustular psoriasis	0.905	0.095	0.000
L52 Erythema nodosum	0.905	0.095	0.000
D50-D53 Nutritional anaemias	0.904	0.096	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.901	0.099	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.900	0.100	0.000
C18.7 Sigmoid colon	0.900	0.100	0.000
B00 Herpesviral [herpes simplex] infections	0.899	0.101	0.000
N18.0 End-stage renal disease	0.899	0.101	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.895	0.105	0.000
I77.1 Stricture of artery	0.894	0.106	0.000
Q80-Q89 Other congenital malformations	0.890	0.110	0.000
N05.1 Focal and segmental glomerular lesions	0.889	0.111	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.889	0.111	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.887	0.113	0.000
H36.0 Diabetic retinopathy	0.887	0.113	0.000
C91.1 Chronic lymphocytic leukaemia	0.885	0.115	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.882	0.118	0.000
D86 Sarcoidosis	0.880	0.120	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.878	0.122	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.876	0.124	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.873	0.127	0.000
M07.3 Other psoriatic arthropathies	0.872	0.128	0.000
G59.0 Diabetic mononeuropathy	0.871	0.129	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.871	0.129	0.000
E55 Vitamin D deficiency	0.870	0.130	0.000
E53 Deficiency of other B group vitamins	0.869	0.131	0.000
G70-G73 Diseases of myoneural junction and muscle	0.869	0.131	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.866	0.134	0.000
D55-D59 Haemolytic anaemias	0.862	0.138	0.000
E88 Other metabolic disorders	0.862	0.138	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.139	0.861
L97 Ulcer of lower limb, not elsewhere classified	0.861	0.139	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.860	0.140	0.000
H36 Retinal disorders in diseases classified elsewhere	0.859	0.141	0.000
B07 Viral warts	0.858	0.142	0.000
C18.9 Colon, unspecified	0.858	0.142	0.000
Q60-Q64 Congenital malformations of the urinary system	0.857	0.143	0.000
E23 Hypofunction and other disorders of pituitary gland	0.857	0.143	0.000
I24.8 Other forms of acute ischaemic heart disease	0.855	0.145	0.000
I27 Other pulmonary heart diseases	0.855	0.145	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.855	0.145	0.000
I24 Other acute ischaemic heart diseases	0.854	0.146	0.000
I20-I25 Ischaemic heart diseases	0.851	0.149	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.850	0.150	0.000
E21.0 Primary hyperparathyroidism	0.849	0.151	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.848	0.152	0.000
E14.1 With ketoacidosis	0.845	0.155	0.000
B02 Zoster [herpes zoster]	0.845	0.155	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.844	0.156	0.000
B15-B19 Viral hepatitis	0.844	0.156	0.000
N04.2 Diffuse membranous glomerulonephritis	0.843	0.157	0.000
E73 Lactose intolerance	0.842	0.158	0.000
I73.9 Peripheral vascular disease, unspecified	0.841	0.159	0.000
E24 Cushing's syndrome	0.841	0.159	0.000
L92.0 Granuloma annulare	0.840	0.160	0.000
H30-H36 Disorders of choroid and retina	0.839	0.161	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.838	0.162	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.837	0.163	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.835	0.165	0.000
Q43 Other congenital malformations of intestine	0.835	0.165	0.000
E78.2 Mixed hyperlipidaemia	0.834	0.166	0.000
Chapter VII Diseases of the eye and adnexa	0.834	0.166	0.000
E10.8 With unspecified complications	0.832	0.167	0.000
C23 Malignant neoplasm of gallbladder	0.830	0.170	0.000
D80 Immunodeficiency with predominantly antibody defects	0.828	0.172	0.000
K25 Gastric ulcer	0.827	0.173	0.000
C81 Hodgkin's disease	0.826	0.174	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.826	0.174	0.000
N18.4 Chronic kidney disease, stage 4	0.826	0.174	0.000
L44 Other papulosquamous disorders	0.825	0.175	0.000
Q51 Congenital malformations of uterus and cervix	0.824	0.176	0.000
E53.8 Deficiency of other specified B group vitamins	0.824	0.176	0.000
B00.9 Herpesviral infection, unspecified	0.824	0.176	0.000
G50 Disorders of trigeminal nerve	0.819	0.181	0.000
N04.1 Focal and segmental glomerular lesions	0.818	0.182	0.000
E06 Thyroiditis	0.818	0.182	0.000
D00-D09 In situ neoplasms	0.815	0.185	0.000
G30-G32 Other degenerative diseases of the nervous system	0.815	0.185	0.000
D51 Vitamin B12 deficiency anaemia	0.815	0.185	0.000
E89.2 Postprocedural hypoparathyroidism	0.811	0.189	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.810	0.190	0.000
I73.0 Raynaud's syndrome	0.810	0.190	0.000
G56.4 Causalgia	0.809	0.191	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.809	0.191	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.808	0.192	0.000
E07 Other disorders of thyroid	0.808	0.192	0.000
M07 Psoriatic and enteropathic arthropathies	0.800	0.193	0.007
L40.3 Pustulosis palmaris et plantaris	0.807	0.193	0.000
E10.0 With coma	0.806	0.194	0.000
E11.4 With neurological complications	0.806	0.194	0.000
I74.5 Embolism and thrombosis of iliac artery	0.805	0.195	0.000
B02.9 Zoster without complication	0.804	0.196	0.000
E55.9 Vitamin D deficiency, unspecified	0.804	0.196	0.000
L50 Urticaria	0.804	0.196	0.000
A15-A19 Tuberculosis	0.801	0.199	0.000
D61 Other aplastic anaemias	0.801	0.199	0.000
D86.3 Sarcoidosis of skin	0.800	0.200	0.000
E21.3 Hyperparathyroidism, unspecified	0.799	0.201	0.000
E10.5 With peripheral circulatory complications	0.798	0.202	0.000
D04 Carcinoma in situ of skin	0.798	0.202	0.000
A63.0 Anogenital (venereal) warts	0.797	0.203	0.000
L20-L30 Dermatitis and eczema	0.797	0.203	0.000
B35-B49 Mycoses	0.796	0.204	0.000
E13 Other specified diabetes mellitus	0.794	0.206	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.794	0.206	0.000
I60-I69 Cerebrovascular diseases	0.791	0.209	0.000
E10.7 With multiple complications	0.790	0.210	0.000
C88 Malignant immunoproliferative diseases	0.789	0.211	0.000
C34.0 Main bronchus	0.789	0.211	0.000
E28 Ovarian dysfunction	0.789	0.211	0.000
I27.9 Pulmonary heart disease, unspecified	0.788	0.212	0.000
Q54 Hypospadias	0.787	0.213	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.786	0.214	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.786	0.214	0.000
C34.8 Overlapping lesion of bronchus and lung	0.785	0.215	0.000
E31 Polyglandular dysfunction	0.785	0.215	0.000
L94 Other localised connective tissue disorders	0.783	0.217	0.000
D73 Diseases of spleen	0.782	0.218	0.000
H34 Retinal vascular occlusions	0.782	0.218	0.000
L93 Lupus erythematosus	0.781	0.219	0.000
L28 Lichen simplex chronicus and prurigo	0.781	0.219	0.000
I27.2 Other secondary pulmonary hypertension	0.780	0.220	0.000
C18.6 Descending colon	0.778	0.222	0.000
K29.0 Acute haemorrhagic gastritis	0.777	0.223	0.000
E78.6 Lipoprotein deficiency	0.776	0.224	0.000
D59 Acquired haemolytic anaemia	0.776	0.224	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.776	0.224	0.000
D86.9 Sarcoidosis, unspecified	0.775	0.225	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.775	0.225	0.000
Q00-Q07 Congenital malformations of the nervous system	0.775	0.225	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.774	0.226	0.000
N17 Acute renal failure	0.774	0.226	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.774	0.226	0.000
I63 Cerebral infarction	0.774	0.226	0.000
E23.6 Other disorders of pituitary gland	0.771	0.229	0.000
E21.2 Other hyperparathyroidism	0.770	0.230	0.000
C60-C63 Malignant neoplasms of male genital organs	0.769	0.231	0.000
L80 Vitiligo	0.769	0.231	0.000
L28.0 Lichen simplex chronicus	0.768	0.232	0.000
I05-I09 Chronic rheumatic heart diseases	0.767	0.232	0.000
C22.9 Liver, unspecified	0.766	0.234	0.000
M05-M14 Inflammatory polyarthropathies	0.748	0.234	0.017
E89.3 Postprocedural hypopituitarism	0.764	0.236	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.763	0.237	0.000
E03.8 Other specified hypothyroidism	0.763	0.237	0.000
E14.5 With peripheral circulatory complications	0.762	0.238	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.761	0.239	0.000
E51 Thiamine deficiency	0.759	0.240	0.000
C34.2 Middle lobe, bronchus or lung	0.759	0.240	0.000
N05.8 Other	0.758	0.242	0.000
C84.5 Other and unspecified T-cell lymphomas	0.758	0.242	0.000
H46 Optic neuritis	0.758	0.242	0.000
C22.1 Intrahepatic bile duct carcinoma	0.757	0.243	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.757	0.243	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.756	0.243	0.000
C38.4 Pleura	0.756	0.244	0.000
G52 Disorders of other cranial nerves	0.756	0.244	0.000
H34.8 Other retinal vascular occlusions	0.755	0.245	0.000
L43 Lichen planus	0.753	0.247	0.000
L40.8 Other psoriasis	0.752	0.247	0.000
E14.4 With neurological complications	0.751	0.249	0.000
G71 Primary disorders of muscles	0.750	0.250	0.000
G56.1 Other lesions of median nerve	0.750	0.250	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.749	0.251	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.746	0.252	0.002
Q60 Renal agenesis and other reduction defects of kidney	0.748	0.252	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.748	0.252	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.746	0.254	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.746	0.254	0.000
L53 Other erythematous conditions	0.744	0.256	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.744	0.256	0.000
E24.0 Pituitary-dependent Cushing's disease	0.744	0.256	0.000
E88.8 Other specified metabolic disorders	0.744	0.256	0.000
E07.8 Other specified disorders of thyroid	0.743	0.257	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.743	0.257	0.000
Q40 Other congenital malformations of upper alimentary tract	0.743	0.257	0.000
C91.9 Lymphoid leukaemia, unspecified	0.742	0.258	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.742	0.258	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.741	0.259	0.000
E20 Hypoparathyroidism	0.741	0.259	0.000
K29.3 Chronic superficial gastritis	0.739	0.261	0.000
L11 Other acantholytic disorders	0.739	0.261	0.000
N10-N16 Renal tubulo-interstitial diseases	0.738	0.262	0.000
C34.9 Bronchus or lung, unspecified	0.737	0.263	0.000
D04.3 Skin of other and unspecified parts of face	0.736	0.264	0.000
K71 Toxic liver disease	0.735	0.265	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.735	0.265	0.000
E73.9 Lactose intolerance, unspecified	0.734	0.266	0.000
D04.5 Skin of trunk	0.733	0.267	0.000
C15 Malignant neoplasm of oesophagus	0.732	0.268	0.000
E14.2 Withrenal complications	0.731	0.269	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.731	0.269	0.000
C95 Leukaemia of unspecified cell type	0.730	0.270	0.000
B91 Sequelae of poliomyelitis	0.730	0.270	0.000
Q85 Phakomatoses, not elsewhere classified	0.729	0.271	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.729	0.271	0.000
I00-I02 Acute rheumatic fever	0.727	0.273	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.722	0.278	0.000
B01 Varicella [chickenpox]	0.722	0.278	0.000
E27.2 Addisonian crisis	0.720	0.280	0.000
D53 Other nutritional anaemias	0.720	0.280	0.000
K31.3 Pylorospasm, not elsewhere classified	0.719	0.281	0.000
E78.4 Other hyperlipidaemia	0.719	0.281	0.000
E16.1 Other hypoglycaemia	0.719	0.281	0.000
C83.7 Burkitt's tumour	0.718	0.282	0.000
E78.8 Other disorders of lipoprotein metabolism	0.718	0.282	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.717	0.283	0.000
E10.6 With other specified complications	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E11.7 With multiple complications	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.717	0.283	0.000
N06 Isolated proteinuria with specified morphological lesion	0.717	0.283	0.000
N01 Rapidly progressive nephritic syndrome	0.717	0.283	0.000
N00 Acute nephritic syndrome	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.717	0.283	0.000
C94 Other leukaemias of specified cell type	0.717	0.283	0.000
C93 Monocytic leukaemia	0.717	0.283	0.000
C86 Other specified types of T/NK-cell lymphoma	0.717	0.283	0.000
C85.0 Lymphosarcoma	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.717	0.283	0.000
L41 Parapsoriasis	0.717	0.283	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E25 Adrenogenital disorders	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.716	0.283	0.000
G58 Other mononeuropathies	0.716	0.284	0.000
K77 Liver disorders in diseases classified elsewhere	0.716	0.284	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.716	0.284	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.716	0.284	0.000
E16.4 Abnormal secretion of gastrin	0.716	0.284	0.000
E16.3 Increased secretion of glucagon	0.716	0.284	0.000
K75.2 Nonspecific reactive hepatitis	0.716	0.284	0.000
K75.1 Phlebitis of portal vein	0.716	0.284	0.000
B18 Chronic viral hepatitis	0.715	0.285	0.000
N04.8 Other	0.715	0.285	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.715	0.285	0.000
N04.6 Dense deposit disease	0.715	0.285	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.715	0.285	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.715	0.285	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.715	0.285	0.000
N04.0 Minor glomerular abnormality	0.715	0.285	0.000
E27.5 Adrenomedullary hyperfunction	0.715	0.285	0.000
E27.0 Other adrenocortical overactivity	0.715	0.285	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.715	0.285	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.715	0.285	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.715	0.285	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.715	0.285	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.715	0.285	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.715	0.285	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.715	0.285	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.715	0.285	0.000
K29.9 Gastroduodenitis, unspecified	0.714	0.286	0.000
Q35-Q37 Cleft lip and cleft palate	0.713	0.286	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.713	0.286	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.713	0.287	0.000
K31.6 Fistula of stomach and duodenum	0.712	0.288	0.000
K31.2 Hourglass stricture and stenosis of stomach	0.712	0.288	0.000
K31.0 Acute dilatation of stomach	0.712	0.288	0.000
I07 Rheumatic tricuspid valve diseases	0.712	0.288	0.000
E84 Cystic fibrosis	0.712	0.288	0.000
E77 Disorders of glycoprotein metabolism	0.712	0.288	0.000
E76 Disorders of glycosaminoglycan metabolism	0.712	0.288	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.712	0.288	0.000
E72 Other disorders of amino-acid metabolism	0.712	0.288	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.712	0.288	0.000
E70 Disorders of aromatic amino-acid metabolism	0.712	0.288	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.712	0.288	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.712	0.288	0.000
D83 Common variable immunodeficiency	0.711	0.289	0.000
G51.4 Facial myokymia	0.711	0.289	0.000
G51.2 Melkersson's syndrome	0.711	0.289	0.000
G51.1 Geniculate ganglionitis	0.711	0.289	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.711	0.289	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.711	0.289	0.000
E89.5 Postprocedural testicular hypofunction	0.711	0.289	0.000
E89.1 Postprocedural hypoinsulinaemia	0.711	0.289	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.708	0.292	0.000
E27.9 Disorder of adrenal gland, unspecified	0.708	0.292	0.000
C83.6 Undifferentiated (diffuse)	0.708	0.292	0.000
C83.5 Lymphoblastic (diffuse)	0.708	0.292	0.000
C83.4 Immunoblastic (diffuse)	0.708	0.292	0.000
C83.2 Mixed small and large cell (diffuse)	0.708	0.292	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.708	0.292	0.000
N05.6 Dense deposit disease	0.708	0.292	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.708	0.292	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.708	0.292	0.000
N05.0 Minor glomerular abnormality	0.708	0.292	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.708	0.292	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.707	0.293	0.000
D50 Iron deficiency anaemia	0.707	0.293	0.000
I27.0 Primary pulmonary hypertension	0.706	0.294	0.000
E23.2 Diabetes insipidus	0.705	0.295	0.000
N11 Chronic tubulo-interstitial nephritis	0.704	0.296	0.000
K31.4 Gastric diverticulum	0.703	0.297	0.000
B37 Candidiasis	0.703	0.297	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.702	0.298	0.000
E89.4 Postprocedural ovarian failure	0.702	0.298	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.702	0.298	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.701	0.298	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.700	0.300	0.000
D74 Methaemoglobinaemia	0.699	0.301	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.699	0.301	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.699	0.301	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.699	0.301	0.000
C31 Malignant neoplasm of accessory sinuses	0.699	0.301	0.000
C33 Malignant neoplasm of trachea	0.699	0.301	0.000
L44.0 Pityriasis rubra pilaris	0.699	0.301	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.699	0.301	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.699	0.301	0.000
K29.4 Chronic atrophic gastritis	0.699	0.301	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.698	0.302	0.000
D82 Immunodeficiency associated with other major defects	0.698	0.302	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.697	0.303	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.696	0.304	0.000
K72 Hepatic failure, not elsewhere classified	0.696	0.304	0.000
D04.6 Skin of upper limb, including shoulder	0.695	0.305	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.695	0.305	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.695	0.305	0.000
A75-A79 Rickettsioses	0.695	0.305	0.000
A70-A74 Other diseases caused by chlamydiae	0.695	0.305	0.000
A20-A28 Certain zoonotic bacterial diseases	0.695	0.305	0.000
B00.5 Herpesviral ocular disease	0.695	0.305	0.000
D72 Other disorders of white blood cells	0.695	0.305	0.000
L94.9 Localised connective tissue disorder, unspecified	0.694	0.306	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.694	0.306	0.000
I77.6 Arteritis, unspecified	0.694	0.306	0.000
K25.4 Chronic or unspecified with haemorrhage	0.694	0.306	0.000
C60 Malignant neoplasm of penis	0.692	0.308	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.692	0.308	0.000
C91.0 Acute lymphoblastic leukaemia	0.692	0.308	0.000
Q52 Other congenital malformations of female genitalia	0.691	0.309	0.000
B17 Other acute viral hepatitis	0.691	0.309	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.691	0.309	0.000
D64.8 Other specified anaemias	0.691	0.309	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.690	0.310	0.000
E63 Other nutritional deficiencies	0.690	0.310	0.000
E56 Other vitamin deficiencies	0.690	0.310	0.000
E50 Vitamin A deficiency	0.690	0.310	0.000
E60 Dietary zinc deficiency	0.690	0.310	0.000
E59 Dietary selenium deficiency	0.690	0.310	0.000
E58 Dietary calcium deficiency	0.690	0.310	0.000
E54 Ascorbic acid deficiency	0.690	0.310	0.000
E52 Niacin deficiency [pellagra]	0.690	0.310	0.000
L10 Pemphigus	0.690	0.310	0.000
L14 Bullous disorders in diseases classified elsewhere	0.690	0.310	0.000
K25.0 Acute with haemorrhage	0.690	0.310	0.000
K90.3 Pancreatic steatorrhoea	0.690	0.310	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.690	0.310	0.000
K90.1 Tropical sprue	0.690	0.310	0.000
K90.0 Coeliac disease	0.690	0.310	0.000
D86.8 Sarcoidosis of other and combined sites	0.690	0.310	0.000
L54 Erythema in diseases classified elsewhere	0.689	0.311	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.688	0.312	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations