TreeWAS – Variant ID: rs429479

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
N40 Hyperplasia of prostate	0.000	0.000	1.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.000	1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	0.980	0.000	0.019
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	0.999	0.001	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.999	0.001	0.000
K40 Inguinal hernia	0.000	0.001	0.999
H30-H36 Disorders of choroid and retina	0.999	0.001	0.000
K90 Intestinal malabsorption	0.998	0.001	0.001
E20-E35 Disorders of other endocrine glands	0.998	0.002	0.000
K90-K93 Other diseases of the digestive system	0.980	0.002	0.019
I73 Other peripheral vascular diseases	0.998	0.002	0.000
E27 Other disorders of adrenal gland	0.998	0.002	0.000
E14 Unspecified diabetes mellitus	0.998	0.002	0.000
E27.1 Primary adrenocortical insufficiency	0.998	0.002	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.002	0.998
H36 Retinal disorders in diseases classified elsewhere	0.997	0.003	0.000
K44 Diaphragmatic hernia	0.000	0.003	0.997
K40-K46 Hernia	0.000	0.003	0.997
H36.0 Diabetic retinopathy	0.997	0.003	0.000
H43-H45 Disorders of vitreous body and globe	0.996	0.004	0.000
I73.9 Peripheral vascular disease, unspecified	0.996	0.004	0.000
Chapter IX Diseases of the circulatory system	0.995	0.005	0.000
D80-D89 Certain disorders involving the immune mechanism	0.995	0.005	0.000
Chapter II Neoplasms	0.994	0.006	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.993	0.007	0.000
E14.3 With ophthalmic complications	0.992	0.008	0.000
E10.2 With renal complications	0.991	0.009	0.000
Chapter VI Diseases of the nervous system	0.991	0.009	0.000
H43 Disorders of vitreous body	0.991	0.009	0.000
E10.1 With ketoacidosis	0.991	0.009	0.000
H25-H28 Disorders of lens	0.990	0.010	0.000
Chapter I Certain infectious and parasitic diseases	0.990	0.010	0.000
B35-B49 Mycoses	0.990	0.010	0.000
M15-M19 Arthrosis	0.989	0.011	0.000
K70-K77 Diseases of liver	0.988	0.012	0.000
K75 Other inflammatory liver diseases	0.988	0.012	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.987	0.013	0.000
H26 Other cataract	0.987	0.013	0.000
M05-M14 Inflammatory polyarthropathies	0.987	0.013	0.000
M17 Gonarthrosis [arthrosis of knee]	0.987	0.013	0.000
B37 Candidiasis	0.987	0.013	0.000
K75.4 Autoimmune hepatitis	0.987	0.013	0.000
H26.9 Cataract, unspecified	0.986	0.014	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.985	0.015	0.000
I74 Arterial embolism and thrombosis	0.984	0.016	0.000
H43.1 Vitreous haemorrhage	0.984	0.016	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.982	0.018	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.979	0.021	0.000
M17.9 Gonarthrosis, unspecified	0.977	0.023	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.975	0.025	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.973	0.027	0.000
D86 Sarcoidosis	0.972	0.028	0.000
E11 Non-insulin-dependent diabetes mellitus	0.971	0.029	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.970	0.030	0.000
E50-E64 Other nutritional deficiencies	0.969	0.031	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.967	0.033	0.000
M31 Other necrotising vasculopathies	0.964	0.036	0.000
E10.4 With neurological complications	0.961	0.039	0.000
C15-C26 Malignant neoplasms of digestive organs	0.960	0.040	0.000
M17.1 Other primary gonarthrosis	0.959	0.041	0.000
D50-D53 Nutritional anaemias	0.959	0.041	0.000
M06 Other rheumatoid arthritis	0.957	0.043	0.000
B37.9 Candidiasis, unspecified	0.957	0.043	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.046	0.954
I77 Other disorders of arteries and arterioles	0.952	0.048	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.951	0.049	0.000
B44 Aspergillosis	0.950	0.050	0.000
D86.9 Sarcoidosis, unspecified	0.950	0.050	0.000
M06.9 Rheumatoid arthritis, unspecified	0.947	0.053	0.000
M23 Internal derangement of knee	0.945	0.055	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.943	0.057	0.000
K72 Hepatic failure, not elsewhere classified	0.943	0.057	0.000
E11.9 Without complications	0.941	0.059	0.000
L50-L54 Urticaria and erythema	0.941	0.059	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.937	0.063	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.934	0.066	0.000
H34 Retinal vascular occlusions	0.934	0.066	0.000
G56 Mononeuropathies of upper limb	0.932	0.068	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.932	0.068	0.000
B37.8 Candidiasis of other sites	0.930	0.070	0.000
L20-L30 Dermatitis and eczema	0.929	0.071	0.000
M31.6 Other giant cell arteritis	0.928	0.072	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.927	0.073	0.000
N40-N51 Diseases of male genital organs	0.000	0.074	0.926
M35.3 Polymyalgia rheumatica	0.924	0.076	0.000
G56.0 Carpal tunnel syndrome	0.923	0.077	0.000
B37.0 Candidal stomatitis	0.923	0.077	0.000
G58 Other mononeuropathies	0.922	0.078	0.000
M34 Systemic sclerosis	0.922	0.078	0.000
D50 Iron deficiency anaemia	0.922	0.078	0.000
C25 Malignant neoplasm of pancreas	0.921	0.079	0.000
N42 Other disorders of prostate	0.000	0.080	0.920
Q38-Q45 Other congenital malformations of the digestive system	0.915	0.085	0.000
M25 Other joint disorders, not elsewhere classified	0.914	0.086	0.000
K90.9 Intestinal malabsorption, unspecified	0.913	0.087	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.910	0.090	0.000
G35 Multiple sclerosis	0.910	0.090	0.000
C81 Hodgkin's disease	0.908	0.092	0.000
K75.8 Other specified inflammatory liver diseases	0.908	0.092	0.000
M22 Disorders of patella	0.907	0.093	0.000
G51 Facial nerve disorders	0.907	0.093	0.000
C34 Malignant neoplasm of bronchus and lung	0.906	0.094	0.000
L30 Other dermatitis	0.904	0.096	0.000
C85.1 B-cell lymphoma, unspecified	0.904	0.096	0.000
E83.1 Disorders of iron metabolism	0.000	0.096	0.904
G58.9 Mononeuropathy, unspecified	0.903	0.097	0.000
H05 Disorders of orbit	0.902	0.098	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.900	0.100	0.000
E11.5 With peripheral circulatory complications	0.899	0.101	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.898	0.102	0.000
D50.9 Iron deficiency anaemia, unspecified	0.898	0.102	0.000
E53 Deficiency of other B group vitamins	0.897	0.103	0.000
I73.0 Raynaud's syndrome	0.894	0.106	0.000
M18 Arthrosis of first carpometacarpal joint	0.894	0.106	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.894	0.106	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.893	0.107	0.000
I77.1 Stricture of artery	0.892	0.108	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.889	0.111	0.000
L30.9 Dermatitis, unspecified	0.888	0.112	0.000
C18 Malignant neoplasm of colon	0.888	0.112	0.000
K73 Chronic hepatitis, not elsewhere classified	0.887	0.113	0.000
H02 Other disorders of eyelid	0.887	0.113	0.000
H34.8 Other retinal vascular occlusions	0.883	0.117	0.000
B25-B34 Other viral diseases	0.880	0.120	0.000
M25.9 Joint disorder, unspecified	0.880	0.120	0.000
I77.6 Arteritis, unspecified	0.879	0.121	0.000
L94 Other localised connective tissue disorders	0.879	0.121	0.000
M65-M68 Disorders of synovium and tendon	0.879	0.121	0.000
D61 Other aplastic anaemias	0.878	0.122	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.875	0.125	0.000
M20.1 Hallux valgus (acquired)	0.000	0.126	0.874
I60-I69 Cerebrovascular diseases	0.870	0.130	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.870	0.130	0.000
C04 Malignant neoplasm of floor of mouth	0.868	0.132	0.000
K72.9 Hepatic failure, unspecified	0.867	0.133	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.867	0.133	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.133	0.867
B44.1 Other pulmonary aspergillosis	0.867	0.133	0.000
M23.3 Other meniscus derangements	0.865	0.135	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.863	0.137	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.861	0.139	0.000
B44.9 Aspergillosis, unspecified	0.861	0.139	0.000
H44 Disorders of globe	0.860	0.140	0.000
E24 Cushing's syndrome	0.860	0.140	0.000
K50-K52 Noninfective enteritis and colitis	0.289	0.140	0.571
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.856	0.144	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.144	0.856
H26.4 After-cataract	0.856	0.144	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.855	0.145	0.000
C25.9 Pancreas, unspecified	0.854	0.146	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.854	0.146	0.000
E61 Deficiency of other nutrient elements	0.853	0.147	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.851	0.149	0.000
M20 Acquired deformities of fingers and toes	0.004	0.149	0.847
C07 Malignant neoplasm of parotid gland	0.850	0.150	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.849	0.151	0.000
E53.8 Deficiency of other specified B group vitamins	0.848	0.152	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.847	0.153	0.000
M10 Gout	0.847	0.153	0.000
H02.5 Other disorders affecting eyelid function	0.846	0.154	0.000
L52 Erythema nodosum	0.846	0.154	0.000
C34.3 Lower lobe, bronchus or lung	0.845	0.155	0.000
M60-M63 Disorders of muscles	0.844	0.156	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.157	0.843
Q50-Q56 Congenital malformations of genital organs	0.843	0.157	0.000
G70-G73 Diseases of myoneural junction and muscle	0.841	0.159	0.000
H46 Optic neuritis	0.840	0.160	0.000
I27 Other pulmonary heart diseases	0.838	0.162	0.000
M25.4 Effusion of joint	0.837	0.163	0.000
G51.9 Disorder of facial nerve, unspecified	0.836	0.164	0.000
E11.3 With ophthalmic complications	0.833	0.167	0.000
M11 Other crystal arthropathies	0.833	0.167	0.000
N42.8 Other specified disorders of prostate	0.000	0.168	0.832
D83 Common variable immunodeficiency	0.831	0.169	0.000
K72.0 Acute and subacute hepatic failure	0.827	0.173	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.176	0.824
E14.9 Without complications	0.821	0.179	0.000
L10-L14 Bullous disorders	0.821	0.179	0.000
L50 Urticaria	0.821	0.179	0.000
E20 Hypoparathyroidism	0.819	0.181	0.000
E70-E90 Metabolic disorders	0.819	0.181	0.000
E13 Other specified diabetes mellitus	0.819	0.181	0.000
D86.0 Sarcoidosis of lung	0.819	0.181	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.819	0.181	0.000
G30-G32 Other degenerative diseases of the nervous system	0.819	0.181	0.000
C18.9 Colon, unspecified	0.816	0.184	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.814	0.186	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.813	0.187	0.000
E10.0 With coma	0.811	0.189	0.000
D80 Immunodeficiency with predominantly antibody defects	0.811	0.189	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.811	0.189	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.810	0.190	0.000
N41 Inflammatory diseases of prostate	0.000	0.190	0.810
M34.9 Systemic sclerosis, unspecified	0.807	0.193	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.806	0.193	0.000
M07 Psoriatic and enteropathic arthropathies	0.805	0.195	0.000
H43.8 Other disorders of vitreous body	0.803	0.197	0.000
B02 Zoster [herpes zoster]	0.803	0.197	0.000
H30 Chorioretinal inflammation	0.803	0.197	0.000
A15-A19 Tuberculosis	0.803	0.197	0.000
H02.3 Blepharochalasis	0.802	0.198	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.800	0.200	0.000
H05.0 Acute inflammation of orbit	0.800	0.200	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.800	0.200	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.800	0.200	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.799	0.201	0.000
G51.0 Bell's palsy	0.799	0.201	0.000
Q00-Q07 Congenital malformations of the nervous system	0.799	0.201	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.798	0.202	0.000
C84.5 Other and unspecified T-cell lymphomas	0.797	0.203	0.000
M67 Other disorders of synovium and tendon	0.796	0.204	0.000
H43.9 Disorder of vitreous body, unspecified	0.795	0.205	0.000
C15 Malignant neoplasm of oesophagus	0.795	0.205	0.000
C25.3 Pancreatic duct	0.794	0.205	0.000
E10.7 With multiple complications	0.794	0.206	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.207	0.793
I70 Atherosclerosis	0.793	0.207	0.000
M22.8 Other disorders of patella	0.791	0.209	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.790	0.210	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.790	0.210	0.000
Q43 Other congenital malformations of intestine	0.788	0.212	0.000
L40-L45 Papulosquamous disorders	0.787	0.212	0.000
B25 Cytomegaloviral disease	0.784	0.216	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.784	0.216	0.000
N42.2 Atrophy of prostate	0.000	0.217	0.783
C06 Malignant neoplasm of other and unspecified parts of mouth	0.783	0.217	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.783	0.217	0.000
M22.3 Other derangements of patella	0.783	0.217	0.000
C34.0 Main bronchus	0.783	0.217	0.000
D55-D59 Haemolytic anaemias	0.782	0.218	0.000
D61.9 Aplastic anaemia, unspecified	0.781	0.219	0.000
C18.4 Transverse colon	0.781	0.219	0.000
I62 Other nontraumatic intracranial haemorrhage	0.780	0.220	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.780	0.220	0.000
H26.1 Traumatic cataract	0.779	0.221	0.000
I60 Subarachnoid haemorrhage	0.779	0.221	0.000
C91 Lymphoid leukaemia	0.779	0.221	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.778	0.222	0.000
I74.8 Embolism and thrombosis of other arteries	0.778	0.222	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.778	0.222	0.000
E10.5 With peripheral circulatory complications	0.777	0.223	0.000
K46 Unspecified abdominal hernia	0.000	0.223	0.777
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.223	0.777
K75.9 Inflammatory liver disease, unspecified	0.776	0.224	0.000
C13 Malignant neoplasm of hypopharynx	0.776	0.224	0.000
M32 Systemic lupus erythematosus	0.775	0.225	0.000
I27.2 Other secondary pulmonary hypertension	0.775	0.225	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.774	0.226	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.774	0.226	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.773	0.226	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.773	0.227	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.772	0.227	0.000
M86-M90 Other osteopathies	0.772	0.228	0.000
C01 Malignant neoplasm of base of tongue	0.772	0.228	0.000
E14.8 With unspecified complications	0.769	0.231	0.000
E07 Other disorders of thyroid	0.769	0.231	0.000
M34.1 CR(E)ST syndrome	0.768	0.232	0.000
H06.2 Dysthyroid exophthalmos	0.768	0.232	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.768	0.232	0.000
E61.1 Iron deficiency	0.768	0.232	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.767	0.233	0.000
N48 Other disorders of penis	0.000	0.233	0.767
C23 Malignant neoplasm of gallbladder	0.767	0.233	0.000
C03 Malignant neoplasm of gum	0.766	0.234	0.000
G50 Disorders of trigeminal nerve	0.765	0.235	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.764	0.236	0.000
L93 Lupus erythematosus	0.762	0.238	0.000
L94.0 Localised scleroderma [morphea]	0.762	0.238	0.000
E14.6 With other specified complications	0.761	0.239	0.000
C04.0 Anterior floor of mouth	0.761	0.239	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.761	0.239	0.000
H02.0 Entropion and trichiasis of eyelid	0.760	0.240	0.000
E14.2 Withrenal complications	0.759	0.241	0.000
D51 Vitamin B12 deficiency anaemia	0.759	0.241	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.758	0.242	0.000
E10.6 With other specified complications	0.758	0.242	0.000
H27 Other disorders of lens	0.758	0.242	0.000
K90.8 Other intestinal malabsorption	0.757	0.243	0.000
H43.2 Crystalline deposits in vitreous body	0.757	0.243	0.000
C16 Malignant neoplasm of stomach	0.757	0.243	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.245	0.755
E14.1 With ketoacidosis	0.755	0.245	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.753	0.247	0.000
C88 Malignant immunoproliferative diseases	0.753	0.247	0.000
E24.2 Drug-induced Cushing's syndrome	0.753	0.247	0.000
L80 Vitiligo	0.752	0.248	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.751	0.249	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.750	0.250	0.000
M06.4 Inflammatory polyarthropathy	0.750	0.250	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.750	0.250	0.000
D84 Other immunodeficiencies	0.750	0.250	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.749	0.251	0.000
M12 Other specific arthropathies	0.749	0.251	0.000
C81.0 Lymphocytic predominance	0.748	0.252	0.000
I27.0 Primary pulmonary hypertension	0.746	0.254	0.000
H02.1 Ectropion of eyelid	0.746	0.254	0.000
H31 Other disorders of choroid	0.745	0.255	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.741	0.259	0.000
N48.1 Balanoposthitis	0.000	0.259	0.741
H05.2 Exophthalmic conditions	0.740	0.260	0.000
E29 Testicular dysfunction	0.740	0.260	0.000
B15-B19 Viral hepatitis	0.740	0.260	0.000
C95 Leukaemia of unspecified cell type	0.739	0.261	0.000
E03.8 Other specified hypothyroidism	0.738	0.262	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.738	0.262	0.000
E23 Hypofunction and other disorders of pituitary gland	0.737	0.262	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.737	0.263	0.000
E55 Vitamin D deficiency	0.737	0.263	0.000
C81.2 Mixed cellularity	0.737	0.263	0.000
M00-M03 Infectious arthropathies	0.734	0.266	0.000
E11.0 With coma	0.732	0.268	0.000
E51 Thiamine deficiency	0.732	0.268	0.000
C18.6 Descending colon	0.731	0.269	0.000
I65.2 Occlusion and stenosis of carotid artery	0.731	0.269	0.000
G12 Spinal muscular atrophy and related syndromes	0.731	0.269	0.000
C81.9 Hodgkin's disease, unspecified	0.731	0.269	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.731	0.269	0.000
H47.2 Optic atrophy	0.730	0.269	0.000
K35-K38 Diseases of appendix	0.725	0.270	0.005
M25.96 Joint disorder, unspecified (Lower leg)	0.729	0.271	0.000
L43 Lichen planus	0.728	0.272	0.000
E14.4 With neurological complications	0.728	0.272	0.000
M86 Osteomyelitis	0.728	0.272	0.000
D50.8 Other iron deficiency anaemias	0.728	0.272	0.000
B02.9 Zoster without complication	0.727	0.273	0.000
M23.5 Chronic instability of knee	0.727	0.273	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.726	0.274	0.000
M67.8 Other specified disorders of synovium and tendon	0.725	0.275	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.724	0.276	0.000
C84.0 Mycosis fungoides	0.723	0.276	0.000
H34.2 Other retinal artery occlusions	0.723	0.277	0.000
M11.2 Other chondrocalcinosis	0.723	0.277	0.000
G52 Disorders of other cranial nerves	0.722	0.278	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.721	0.279	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.721	0.279	0.000
M17.3 Other posttraumatic gonarthrosis	0.721	0.279	0.000
M23.1 Discoid meniscus (congenital)	0.720	0.279	0.000
Q45 Other congenital malformations of digestive system	0.718	0.282	0.000
L92.0 Granuloma annulare	0.718	0.282	0.000
L27 Dermatitis due to substances taken internally	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
L94.2 Calcinosis cutis	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.8 Other specified systemic involvement of connective tissue	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
M35.2 Behcet's disease	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
M15 Polyarthrosis	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.284	0.716
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.284	0.716
H32 Chorioretinal disorders in diseases classified elsewhere	0.716	0.284	0.000
H01 Other inflammation of eyelid	0.716	0.284	0.000
M62 Other disorders of muscle	0.716	0.284	0.000
K90.3 Pancreatic steatorrhoea	0.715	0.284	0.001
K90.2 Blind loop syndrome, not elsewhere classified	0.715	0.284	0.001
K90.1 Tropical sprue	0.715	0.284	0.001
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E31 Polyglandular dysfunction	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.702	0.284	0.014
B25.9 Cytomegaloviral disease, unspecified	0.716	0.284	0.000
D53 Other nutritional anaemias	0.716	0.284	0.000
E27.5 Adrenomedullary hyperfunction	0.715	0.284	0.000
E27.0 Other adrenocortical overactivity	0.715	0.284	0.000
E40-E46 Malnutrition	0.715	0.285	0.000
E14.7 With multiple complications	0.715	0.285	0.000
E14.5 With peripheral circulatory complications	0.715	0.285	0.000
E14.0 With coma	0.715	0.285	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.715	0.285	0.000
K44.1 Diaphragmatic hernia with gangrene	0.000	0.285	0.715
C02.9 Tongue, unspecified	0.715	0.285	0.000
M23.9 Internal derangement of knee, unspecified	0.715	0.285	0.000
H47.3 Other disorders of optic disk	0.715	0.285	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.714	0.286	0.000
L23 Allergic contact dermatitis	0.714	0.286	0.000
I00-I02 Acute rheumatic fever	0.714	0.286	0.000
D83.9 Common variable immunodeficiency, unspecified	0.713	0.287	0.000
B49 Unspecified mycosis	0.713	0.287	0.000
D82 Immunodeficiency associated with other major defects	0.713	0.287	0.000
D81 Combined immunodeficiencies	0.713	0.287	0.000
G71 Primary disorders of muscles	0.712	0.287	0.000
E10.8 With unspecified complications	0.712	0.288	0.000
H44.0 Purulent endophthalmitis	0.712	0.288	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.712	0.288	0.000
C94 Other leukaemias of specified cell type	0.712	0.288	0.000
C93 Monocytic leukaemia	0.712	0.288	0.000
C86 Other specified types of T/NK-cell lymphoma	0.712	0.288	0.000
M70-M79 Other soft tissue disorders	0.711	0.289	0.000
C11 Malignant neoplasm of nasopharynx	0.710	0.289	0.000
H43.0 Vitreous prolapse	0.710	0.290	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.710	0.290	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.710	0.290	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.710	0.290	0.000
A75-A79 Rickettsioses	0.710	0.290	0.000
A70-A74 Other diseases caused by chlamydiae	0.710	0.290	0.000
A20-A28 Certain zoonotic bacterial diseases	0.710	0.290	0.000
B48 Other mycoses, not elsewhere classified	0.709	0.290	0.000
B47 Mycetoma	0.709	0.290	0.000
B46 Zygomycosis	0.709	0.290	0.000
B45 Cryptococcosis	0.709	0.290	0.000
B43 Chromomycosis and phaeomycotic abscess	0.709	0.290	0.000
B42 Sporotrichosis	0.709	0.290	0.000
B41 Paracoccidioidomycosis	0.709	0.290	0.000
B40 Blastomycosis	0.709	0.290	0.000
B39 Histoplasmosis	0.709	0.290	0.000
B38 Coccidioidomycosis	0.709	0.290	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.709	0.291	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.709	0.291	0.000
K77 Liver disorders in diseases classified elsewhere	0.708	0.291	0.000
K71 Toxic liver disease	0.708	0.291	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.708	0.292	0.000
K75.2 Nonspecific reactive hepatitis	0.708	0.292	0.000
K75.1 Phlebitis of portal vein	0.708	0.292	0.000
L53 Other erythematous conditions	0.708	0.292	0.000
H02.6 Xanthelasma of eyelid	0.708	0.292	0.000
H26.3 Drug-induced cataract	0.708	0.292	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.708	0.292	0.000
M08 Juvenile arthritis	0.708	0.292	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.708	0.292	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.708	0.292	0.000
B37.7 Candidal septicaemia	0.708	0.292	0.000
B37.6 Candidal endocarditis	0.708	0.292	0.000
B37.5 Candidal meningitis	0.708	0.292	0.000
B37.1 Pulmonary candidiasis	0.708	0.292	0.000
C25.2 Tail of pancreas	0.707	0.293	0.000
M34.8 Other forms of systemic sclerosis	0.707	0.293	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.706	0.293	0.000
C85.0 Lymphosarcoma	0.706	0.293	0.000
C69 Malignant neoplasm of eye and adnexa	0.706	0.294	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.706	0.294	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.706	0.294	0.000
I63 Cerebral infarction	0.706	0.294	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.706	0.294	0.000
M10.0 Idiopathic gout	0.705	0.295	0.000
M91-M94 Chondropathies	0.705	0.295	0.000
L94.8 Other specified localised connective tissue disorders	0.704	0.296	0.000
E16.1 Other hypoglycaemia	0.704	0.296	0.000
M25.46 Effusion of joint (Lower leg)	0.704	0.296	0.000
B34 Viral infection of unspecified site	0.704	0.296	0.000
H05.8 Other disorders of orbit	0.704	0.296	0.000
C25.1 Body of pancreas	0.703	0.297	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.297	0.702
I77.8 Other specified disorders of arteries and arterioles	0.703	0.297	0.000
L51 Erythema multiforme	0.702	0.298	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.298	0.702
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.702	0.298	0.000
C00 Malignant neoplasm of lip	0.702	0.298	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations