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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4658627
log Bayes Factor = <0.0001
Chromosome 1   position 244,511,176  (GRCh37) Explore rs4658627 on Ensembl!
Variant rs4658627 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
F60.3 Emotionally unstable personality disorder
0.064 0.936 0.000
F60 Specific personality disorders
0.059 0.941 0.000
F60.6 Anxious [avoidant] personality disorder
0.048 0.952 0.000
F60.0 Paranoid personality disorder
0.048 0.952 0.000
F60.5 Anankastic personality disorder
0.047 0.953 0.000
F60.9 Personality disorder, unspecified
0.046 0.954 0.000
F60-F69 Disorders of adult personality and behaviour
0.043 0.957 0.000
F60.8 Other specific personality disorders
0.042 0.958 0.000
F60.4 Histrionic personality disorder
0.042 0.958 0.000
F60.2 Dissocial personality disorder
0.042 0.958 0.000
F60.1 Schizoid personality disorder
0.042 0.958 0.000
F60.7 Dependent personality disorder
0.040 0.960 0.000
F69 Unspecified disorder of adult personality and behaviour
0.037 0.963 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.033 0.967 0.000
F64 Gender identity disorders
0.033 0.967 0.000
F68 Other disorders of adult personality and behaviour
0.031 0.969 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.031 0.969 0.000
F65 Disorders of sexual preference
0.031 0.969 0.000
F63 Habit and impulse disorders
0.031 0.969 0.000
F61 Mixed and other personality disorders
0.031 0.969 0.000
F62.9 Enduring personality change, unspecified
0.026 0.974 0.000
F64.0 Transsexualism
0.025 0.975 0.000
F62.8 Other enduring personality changes
0.024 0.976 0.000
F62.1 Enduring personality change after psychiatric illness
0.024 0.976 0.000
F62.0 Enduring personality change after catastrophic experience
0.024 0.976 0.000
F64.9 Gender identity disorder, unspecified
0.023 0.976 0.000
F64.8 Other gender identity disorders
0.023 0.976 0.000
F64.2 Gender identity disorder of childhood
0.023 0.976 0.000
F64.1 Dual-role transvestism
0.023 0.976 0.000
F63.9 Habit and impulse disorder, unspecified
0.023 0.977 0.000
F63.8 Other habit and impulse disorders
0.023 0.977 0.000
F63.3 Trichotillomania
0.023 0.977 0.000
F63.2 Pathological stealing [kleptomania]
0.023 0.977 0.000
F63.1 Pathological fire-setting [pyromania]
0.023 0.977 0.000
F63.0 Pathological gambling
0.023 0.977 0.000
F65.9 Disorder of sexual preference, unspecified
0.023 0.977 0.000
F65.8 Other disorders of sexual preference
0.023 0.977 0.000
F65.6 Multiple disorders of sexual preference
0.023 0.977 0.000
F65.5 Sadomasochism
0.023 0.977 0.000
F65.4 Paedophilia
0.023 0.977 0.000
F65.3 Voyeurism
0.023 0.977 0.000
F65.2 Exhibitionism
0.023 0.977 0.000
F65.1 Fetishistic transvestism
0.023 0.977 0.000
F65.0 Fetishism
0.023 0.977 0.000
F66.9 Psychosexual development disorder, unspecified
0.023 0.977 0.000
F66.8 Other psychosexual development disorders
0.023 0.977 0.000
F66.2 Sexual relationship disorder
0.023 0.977 0.000
F66.1 Egodystonic sexual orientation
0.023 0.977 0.000
F66.0 Sexual maturation disorder
0.023 0.977 0.000
F68.8 Other specified disorders of adult personality and behaviour
0.023 0.977 0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]
0.023 0.977 0.000
F68.0 Elaboration of physical symptoms for psychological reasons
0.023 0.977 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.019 0.981 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.982 0.018
D36.1 Peripheral nerves and autonomic nervous system
0.000 0.984 0.016
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.984 0.016
F20 Schizophrenia
0.015 0.985 0.000
Chapter V Mental and behavioural disorders
0.015 0.985 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.014 0.986 0.000
F20.0 Paranoid schizophrenia
0.014 0.986 0.000
F80-F89 Disorders of psychological development
0.014 0.986 0.000
F20.5 Residual schizophrenia
0.013 0.987 0.000
F81 Specific developmental disorders of scholastic skills
0.013 0.987 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.013 0.987 0.000
Z50.8 Care involving use of rehabilitation procedures
0.000 0.987 0.013
F81.9 Developmental disorder of scholastic skills, unspecified
0.012 0.988 0.000
M07.3 Other psoriatic arthropathies
0.000 0.988 0.012
E04.9 Non-toxic goitre, unspecified
0.012 0.988 0.000
F20.9 Schizophrenia, unspecified
0.012 0.988 0.000
N70.1 Chronic salpingitis and oophoritis
0.012 0.988 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.988 0.012
O75.3 Other infection during labour
0.012 0.988 0.000
F80 Specific developmental disorders of speech and language
0.012 0.988 0.000
E04 Other non-toxic goitre
0.011 0.989 0.000
O75.8 Other specified complications of labour and delivery
0.011 0.989 0.000
F20.8 Other schizophrenia
0.011 0.989 0.000
F20.6 Simple schizophrenia
0.011 0.989 0.000
F20.4 Postschizophrenic depression
0.011 0.989 0.000
F20.3 Undifferentiated schizophrenia
0.011 0.989 0.000
F20.2 Catatonic schizophrenia
0.011 0.989 0.000
F20.1 Hebephrenic schizophrenia
0.011 0.989 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.010 0.989 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.011 0.989 0.000
F29 Unspecified nonorganic psychosis
0.011 0.989 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.989 0.011
F02 Dementia in other diseases classified elsewhere
0.010 0.989 0.000
F00 Dementia in Alzheimer's disease
0.010 0.989 0.000
F28 Other nonorganic psychotic disorders
0.010 0.990 0.000
F24 Induced delusional disorder
0.010 0.990 0.000
F21 Schizotypal disorder
0.010 0.990 0.000
E04.1 Non-toxic single thyroid nodule
0.010 0.990 0.000
F25 Schizoaffective disorders
0.010 0.990 0.000
F23 Acute and transient psychotic disorders
0.010 0.990 0.000
F02.3 Dementia in Parkinson's disease
0.010 0.990 0.000
O75.0 Maternal distress during labour and delivery
0.010 0.990 0.000
F89 Unspecified disorder of psychological development
0.010 0.990 0.000
F88 Other disorders of psychological development
0.010 0.990 0.000
F83 Mixed specific developmental disorders
0.010 0.990 0.000
F82 Specific developmental disorder of motor function
0.010 0.990 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.010 0.990 0.000
F70-F79 Mental retardation
0.010 0.990 0.000
E04.2 Non-toxic multinodular goitre
0.010 0.990 0.000
F84 Pervasive developmental disorders
0.010 0.990 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.010 0.990 0.000
F99-F99 Unspecified mental disorder
0.010 0.990 0.000
F81.8 Other developmental disorders of scholastic skills
0.009 0.990 0.000
F81.3 Mixed disorder of scholastic skills
0.009 0.990 0.000
F81.2 Specific disorder of arithmetical skills
0.009 0.990 0.000
F81.1 Specific spelling disorder
0.009 0.990 0.000
F81.0 Specific reading disorder
0.009 0.990 0.000
O75.9 Complication of labour and delivery, unspecified
0.009 0.990 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.009 0.990 0.000
O75.4 Other complications of obstetric surgery and procedures
0.009 0.990 0.000
O75.1 Shock during or following labour and delivery
0.009 0.990 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.990 0.009
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.009 0.991 0.000
N70 Salpingitis and oophoritis
0.009 0.991 0.000
F80.1 Expressive language disorder
0.009 0.991 0.000
F80.2 Receptive language disorder
0.009 0.991 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.991 0.009
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.991 0.009
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.991 0.009
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.991 0.009
N70.0 Acute salpingitis and oophoritis
0.009 0.991 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.991 0.009
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.009 0.991 0.000
F22 Persistent delusional disorders
0.009 0.991 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.009 0.991 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.991 0.008
F80.9 Developmental disorder of speech and language, unspecified
0.008 0.991 0.000
F80.8 Other developmental disorders of speech and language
0.008 0.991 0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]
0.008 0.991 0.000
F80.0 Specific speech articulation disorder
0.008 0.991 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.009 0.991 0.000
F32 Depressive episode
0.008 0.992 0.000
E04.8 Other specified non-toxic goitre
0.008 0.992 0.000
F32.9 Depressive episode, unspecified
0.008 0.992 0.000
F45 Somatoform disorders
0.008 0.992 0.000
E06 Thyroiditis
0.008 0.992 0.000
F30-F39 Mood [affective] disorders
0.008 0.992 0.000
E06.3 Autoimmune thyroiditis
0.008 0.992 0.000
F25.9 Schizoaffective disorder, unspecified
0.008 0.992 0.000
F09 Unspecified organic or symptomatic mental disorder
0.008 0.992 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.008 0.992 0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.008 0.992 0.000
F95 Tic disorders
0.008 0.992 0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence
0.008 0.992 0.000
F93 Emotional disorders with onset specific to childhood
0.008 0.992 0.000
F92 Mixed disorders of conduct and emotions
0.008 0.992 0.000
F91 Conduct disorders
0.008 0.992 0.000
F90 Hyperkinetic disorders
0.008 0.992 0.000
E04.0 Non-toxic diffuse goitre
0.008 0.992 0.000
F25.2 Schizoaffective disorder, mixed type
0.008 0.992 0.000
F02.0 Dementia in Pick's disease
0.008 0.992 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.008 0.992 0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.008 0.992 0.000
F02.2 Dementia in Huntington's disease
0.008 0.992 0.000
F02.1 Dementia in Creutzfeldt-Jakob disease
0.008 0.992 0.000
F07.2 Postconcussional syndrome
0.008 0.992 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.008 0.992 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.008 0.992 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.008 0.992 0.000
F25.8 Other schizoaffective disorders
0.008 0.992 0.000
F23.8 Other acute and transient psychotic disorders
0.007 0.992 0.000
F23.3 Other acute predominantly delusional psychotic disorders
0.007 0.992 0.000
F23.2 Acute schizophrenia-like psychotic disorder
0.007 0.992 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.007 0.992 0.000
F45.0 Somatisation disorder
0.008 0.992 0.000
E00-E07 Disorders of thyroid gland
0.008 0.992 0.000
E06.9 Thyroiditis, unspecified
0.008 0.992 0.000
D36 Benign neoplasm of other and unspecified sites
0.000 0.992 0.007
F25.1 Schizoaffective disorder, depressive type
0.007 0.993 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.007 0.993 0.000
F78 Other mental retardation
0.007 0.993 0.000
F73 Profound mental retardation
0.007 0.993 0.000
F72 Severe mental retardation
0.007 0.993 0.000
F71 Moderate mental retardation
0.007 0.993 0.000
F70 Mild mental retardation
0.007 0.993 0.000
Z90.5 Acquired absence of kidney
0.007 0.993 0.000
F84.9 Pervasive developmental disorder, unspecified
0.007 0.993 0.000
F84.8 Other pervasive developmental disorders
0.007 0.993 0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements
0.007 0.993 0.000
F84.3 Other childhood disintegrative disorder
0.007 0.993 0.000
F84.2 Rett's syndrome
0.007 0.993 0.000
F84.1 Atypical autism
0.007 0.993 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.993 0.007
F44 Dissociative [conversion] disorders
0.007 0.993 0.000
F45.9 Somatoform disorder, unspecified
0.007 0.993 0.000
F84.0 Childhood autism
0.007 0.993 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.007 0.993 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.007 0.993 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.007 0.993 0.000
F25.0 Schizoaffective disorder, manic type
0.007 0.993 0.000
J30.1 Allergic rhinitis due to pollen
0.007 0.993 0.000
F45.8 Other somatoform disorders
0.007 0.993 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.007 0.993 0.000
F84.5 Asperger's syndrome
0.007 0.993 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.007 0.993 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.993 0.007
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
0.006 0.993 0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
0.006 0.993 0.000
F07.1 Postencephalitic syndrome
0.006 0.993 0.000
F39 Unspecified mood [affective] disorder
0.007 0.993 0.000
F79 Unspecified mental retardation
0.006 0.993 0.000
F22.9 Persistent delusional disorder, unspecified
0.006 0.993 0.000
F22.8 Other persistent delusional disorders
0.006 0.993 0.000
F32.1 Moderate depressive episode
0.007 0.993 0.000
F07.0 Organic personality disorder
0.006 0.993 0.000
F45.2 Hypochondriacal disorder
0.006 0.993 0.000
E06.5 Other chronic thyroiditis
0.006 0.993 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.006 0.993 0.000
F38 Other mood [affective] disorders
0.006 0.993 0.000
D36.7 Other specified sites
0.000 0.994 0.006
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.006 0.994 0.001
F48 Other neurotic disorders
0.006 0.994 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.006 0.994 0.000
M81.98 Osteoporosis, unspecified (Other)
0.006 0.994 0.000
F45.1 Undifferentiated somatoform disorder
0.006 0.994 0.000
E06.4 Drug-induced thyroiditis
0.006 0.994 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.006 0.994 0.000
E06.1 Subacute thyroiditis
0.006 0.994 0.000
E06.0 Acute thyroiditis
0.006 0.994 0.000
F44.5 Dissociative convulsions
0.006 0.994 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.994 0.006
F45.4 Persistent somatoform pain disorder
0.006 0.994 0.000
F90.9 Hyperkinetic disorder, unspecified
0.006 0.994 0.000
F90.8 Other hyperkinetic disorders
0.006 0.994 0.000
F90.1 Hyperkinetic conduct disorder
0.006 0.994 0.000
F90.0 Disturbance of activity and attention
0.006 0.994 0.000
F91.9 Conduct disorder, unspecified
0.006 0.994 0.000
F91.8 Other conduct disorders
0.006 0.994 0.000
F91.3 Oppositional defiant disorder
0.006 0.994 0.000
F91.2 Socialised conduct disorder
0.006 0.994 0.000
F91.1 Unsocialised conduct disorder
0.006 0.994 0.000
F91.0 Conduct disorder confined to the family context
0.006 0.994 0.000
F92.9 Mixed disorder of conduct and emotions, unspecified
0.006 0.994 0.000
F92.8 Other mixed disorders of conduct and emotions
0.006 0.994 0.000
F92.0 Depressive conduct disorder
0.006 0.994 0.000
F93.9 Childhood emotional disorder, unspecified
0.006 0.994 0.000
F93.8 Other childhood emotional disorders
0.006 0.994 0.000
F93.3 Sibling rivalry disorder
0.006 0.994 0.000
F93.2 Social anxiety disorder of childhood
0.006 0.994 0.000
F93.1 Phobic anxiety disorder of childhood
0.006 0.994 0.000
F93.0 Separation anxiety disorder of childhood
0.006 0.994 0.000
F94.9 Childhood disorder of social functioning, unspecified
0.006 0.994 0.000
F94.8 Other childhood disorders of social functioning
0.006 0.994 0.000
F94.2 Disinhibited attachment disorder of childhood
0.006 0.994 0.000
F94.1 Reactive attachment disorder of childhood
0.006 0.994 0.000
F94.0 Elective mutism
0.006 0.994 0.000
F95.9 Tic disorder, unspecified
0.006 0.994 0.000
F95.8 Other tic disorders
0.006 0.994 0.000
F95.2 Combined vocal and multiple motor tic disorder [de la Tourette]
0.006 0.994 0.000
F95.1 Chronic motor or vocal tic disorder
0.006 0.994 0.000
F95.0 Transient tic disorder
0.006 0.994 0.000
F98.9 Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.006 0.994 0.000
F98.8 Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.006 0.994 0.000
F98.6 Cluttering
0.006 0.994 0.000
F98.5 Stuttering [stammering]
0.006 0.994 0.000
F98.4 Stereotyped movement disorders
0.006 0.994 0.000
F98.3 Pica of infancy and childhood
0.006 0.994 0.000
F98.2 Feeding disorder of infancy and childhood
0.006 0.994 0.000
F98.1 Nonorganic encopresis
0.006 0.994 0.000
F98.0 Nonorganic enuresis
0.006 0.994 0.000
F99 Mental disorder, not otherwise specified
0.006 0.994 0.000
F42 Obsessive-compulsive disorder
0.006 0.994 0.000
Z34.0 Supervision of normal first pregnancy
0.006 0.994 0.000
F01 Vascular dementia
0.005 0.994 0.001
F33 Recurrent depressive disorder
0.006 0.994 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.006 0.994 0.000
E00 Congenital iodine-deficiency syndrome
0.006 0.994 0.000
F32.8 Other depressive episodes
0.006 0.994 0.000
F70.9 Mild mental retardation (Without mention of impairment of behaviour)
0.005 0.994 0.000
F70.8 Mild mental retardation (Other impairments of behaviour)
0.005 0.994 0.000
F70.1 Mild mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.005 0.994 0.000
F70.0 Mild mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.005 0.994 0.000
F71.9 Moderate mental retardation (Without mention of impairment of behaviour)
0.005 0.994 0.000
F71.8 Moderate mental retardation (Other impairments of behaviour)
0.005 0.994 0.000
F71.1 Moderate mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.005 0.994 0.000
F71.0 Moderate mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.005 0.994 0.000
F72.9 Severe mental retardation (Without mention of impairment of behaviour)
0.005 0.994 0.000
F72.8 Severe mental retardation (Other impairments of behaviour)
0.005 0.994 0.000
F72.1 Severe mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.005 0.994 0.000
F72.0 Severe mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.005 0.994 0.000
F73.9 Profound mental retardation (Without mention of impairment of behaviour)
0.005 0.994 0.000
F73.8 Profound mental retardation (Other impairments of behaviour)
0.005 0.994 0.000
F73.1 Profound mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.005 0.994 0.000
F73.0 Profound mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.005 0.994 0.000
F78.9 Other mental retardation (Without mention of impairment of behaviour)
0.005 0.994 0.000
F78.8 Other mental retardation (Other impairments of behaviour)
0.005 0.994 0.000
F78.1 Other mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.005 0.994 0.000
F78.0 Other mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.005 0.994 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.005 0.994 0.000
Z43.3 Attention to colostomy
0.000 0.995 0.005
F44.8 Other dissociative [conversion] disorders
0.005 0.995 0.000
F44.7 Mixed dissociative [conversion] disorders
0.005 0.995 0.000
F44.6 Dissociative anaesthesia and sensory loss
0.005 0.995 0.000
F44.3 Trance and possession disorders
0.005 0.995 0.000
F44.2 Dissociative stupor
0.005 0.995 0.000
F44.1 Dissociative fugue
0.005 0.995 0.000
F44.0 Dissociative amnesia
0.005 0.995 0.000
F44.4 Dissociative motor disorders
0.005 0.995 0.000
F45.3 Somatoform autonomic dysfunction
0.005 0.995 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.005 0.995 0.000
F51 Nonorganic sleep disorders
0.005 0.995 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.005 0.995 0.000
F55 Abuse of non-dependence-producing substances
0.005 0.995 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.005 0.995 0.000
D36.0 Lymph nodes
0.000 0.995 0.005
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.005 0.995 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.995 0.005
E02 Subclinical iodine-deficiency hypothyroidism
0.005 0.995 0.000
D36.9 Benign neoplasm of unspecified site
0.000 0.995 0.005
O14.9 Preeclampsia, unspecified
0.000 0.995 0.005
F34 Persistent mood [affective] disorders
0.005 0.995 0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.005 0.995 0.000
F38.0 Other single mood [affective] disorders
0.005 0.995 0.000
H18.5 Hereditary corneal dystrophies
0.005 0.995 0.000
F79.8 Unspecified mental retardation (Other impairments of behaviour)
0.005 0.995 0.000
F79.1 Unspecified mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.005 0.995 0.000
F79.0 Unspecified mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.005 0.995 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.005 0.995 0.000
M81.9 Osteoporosis, unspecified
0.005 0.995 0.000
A49.0 Staphylococcal infection, unspecified
0.005 0.995 0.000
S29.9 Unspecified injury of thorax
0.000 0.995 0.005
F38.8 Other specified mood [affective] disorders
0.005 0.995 0.000
F38.1 Other recurrent mood [affective] disorders
0.005 0.995 0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.004 0.995 0.001
F06.6 Organic emotionally labile [asthenic] disorder
0.004 0.995 0.001
F06.5 Organic dissociative disorder
0.004 0.995 0.001
F06.4 Organic anxiety disorder
0.004 0.995 0.001
F06.3 Organic mood [affective] disorders
0.004 0.995 0.001
F06.2 Organic delusional [schizophrenia-like] disorder
0.004 0.995 0.001
F06.1 Organic catatonic disorder
0.004 0.995 0.001
F06.0 Organic hallucinosis
0.004 0.995 0.001
F22.0 Delusional disorder
0.005 0.995 0.000
F48.9 Neurotic disorder, unspecified
0.005 0.995 0.000
F42.0 Predominantly obsessional thoughts or ruminations
0.005 0.995 0.000
F48.8 Other specified neurotic disorders
0.005 0.995 0.000
F48.1 Depersonalisation-derealisation syndrome
0.005 0.995 0.000
E05.5 Thyroid crisis or storm
0.005 0.995 0.000
E05.4 Thyrotoxicosis factitia
0.005 0.995 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.005 0.995 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.005 0.995 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.005 0.995 0.000
E05.8 Other thyrotoxicosis
0.005 0.995 0.000
K63.3 Ulcer of intestine
0.000 0.995 0.005
E03 Other hypothyroidism
0.005 0.995 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.005 0.995 0.000
F48.0 Neurasthenia
0.004 0.995 0.000
H18 Other disorders of cornea
0.005 0.995 0.000
F40 Phobic anxiety disorders
0.005 0.995 0.000
F42.8 Other obsessive-compulsive disorders
0.004 0.995 0.000
F42.2 Mixed obsessional thoughts and acts
0.004 0.995 0.000
F42.1 Predominantly compulsive acts [obsessional rituals]
0.004 0.995 0.000
F32.0 Mild depressive episode
0.004 0.995 0.000
F43 Reaction to severe stress, and adjustment disorders
0.004 0.995 0.000
F01.8 Other vascular dementia
0.004 0.995 0.001
F01.3 Mixed cortical and subcortical vascular dementia
0.004 0.995 0.001
F01.2 Subcortical vascular dementia
0.004 0.995 0.001
F01.1 Multi-infarct dementia
0.004 0.995 0.001
F01.0 Vascular dementia of acute onset
0.004 0.995 0.001
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.004 0.996 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.004 0.996 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.004 0.996 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.004 0.996 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.004 0.996 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.004 0.996 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.004 0.996 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.004 0.996 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.004 0.996 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.004 0.996 0.000
F33.8 Other recurrent depressive disorders
0.004 0.996 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.004 0.996 0.000
A49.8 Other bacterial infections of unspecified site
0.004 0.996 0.000
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)
0.004 0.996 0.000
H18.8 Other specified disorders of cornea
0.004 0.996 0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.004 0.996 0.000
F53.9 Puerperal mental disorder, unspecified
0.004 0.996 0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.004 0.996 0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.004 0.996 0.000
E03.8 Other specified hypothyroidism
0.004 0.996 0.000
F51.9 Nonorganic sleep disorder, unspecified
0.004 0.996 0.000
F51.8 Other nonorganic sleep disorders
0.004 0.996 0.000
F51.5 Nightmares
0.004 0.996 0.000
F51.4 Sleep terrors [night terrors]
0.004 0.996 0.000
F51.3 Sleepwalking [somnambulism]
0.004 0.996 0.000
F51.2 Nonorganic disorder of the sleep-wake schedule
0.004 0.996 0.000
F51.1 Nonorganic hypersomnia
0.004 0.996 0.000
F51.0 Nonorganic insomnia
0.004 0.996 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.004 0.996 0.000
A49 Bacterial infection of unspecified site
0.004 0.996 0.000
M07.6 Other enteropathic arthropathies
0.000 0.996 0.004
M07.5 Arthropathy in ulcerative colitis
0.000 0.996 0.004
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.996 0.004
M07.2 Psoriatic spondylitis
0.000 0.996 0.004
M07.1 Arthritis mutilans
0.000 0.996 0.004
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.996 0.004
F50 Eating disorders
0.004 0.996 0.001
F34.9 Persistent mood [affective] disorder, unspecified
0.004 0.996 0.000
F34.8 Other persistent mood [affective] disorders
0.004 0.996 0.000
F34.0 Cyclothymia
0.004 0.996 0.000
E07 Other disorders of thyroid
0.004 0.996 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.996 0.004
H18.2 Other corneal oedema
0.004 0.996 0.000
H18.4 Corneal degeneration
0.004 0.996 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.004 0.996 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.004 0.996 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.004 0.996 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.004 0.996 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.004 0.996 0.000
F40.0 Agoraphobia
0.004 0.996 0.000
F43.9 Reaction to severe stress, unspecified
0.004 0.996 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.004 0.996 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.996 0.004
F42.9 Obsessive-compulsive disorder, unspecified
0.004 0.996 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.004 0.996 0.000
A49.1 Streptococcal infection, unspecified
0.004 0.996 0.000
F43.1 Posttraumatic stress disorder
0.004 0.996 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.004 0.996 0.000
F30 Manic episode
0.003 0.996 0.000
E03.5 Myxoedema coma
0.004 0.996 0.000
E03.4 Atrophy of thyroid (acquired)
0.004 0.996 0.000
E03.3 Postinfectious hypothyroidism
0.004 0.996 0.000
E03.1 Congenital hypothyroidism without goitre
0.004 0.996 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.004 0.996 0.000
Q07.0 Arnold-Chiari syndrome
0.004 0.996 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.004 0.996 0.000
H18.1 Bullous keratopathy
0.004 0.996 0.000
H18.7 Other corneal deformities
0.003 0.996 0.000
H18.3 Changes in corneal membranes
0.003 0.996 0.000
F40.8 Other phobic anxiety disorders
0.003 0.996 0.000
F40.1 Social phobias
0.003 0.996 0.000
H18.6 Keratoconus
0.003 0.996 0.000
F43.8 Other reactions to severe stress
0.003 0.996 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.003 0.996 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.004 0.996 0.000
H18.0 Corneal pigmentations and deposits
0.003 0.997 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.003 0.997 0.000
H18.9 Disorder of cornea, unspecified
0.003 0.997 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.003 0.997 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.003 0.997 0.000
E05.9 Thyrotoxicosis, unspecified
0.003 0.997 0.000
F40.9 Phobic anxiety disorder, unspecified
0.003 0.997 0.000
H16.0 Corneal ulcer
0.003 0.997 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.997 0.003
F50.2 Bulimia nervosa
0.003 0.997 0.000
Q07 Other congenital malformations of nervous system
0.003 0.997 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.003 0.997 0.000
F14.1 Harmful use
0.003 0.997 0.000
R76.8 Other specified abnormal immunological findings in serum
0.003 0.997 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.003 0.997 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.003 0.997 0.000
Q80-Q89 Other congenital malformations
0.003 0.997 0.000
F11 Mental and behavioural disorders due to use of opioids
0.003 0.997 0.000
E07.8 Other specified disorders of thyroid
0.003 0.997 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.003 0.997 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.997 0.003
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.997 0.003
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.997 0.003
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.997 0.003
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.997 0.003
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.997 0.003
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.997 0.003
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.997 0.003
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.997 0.003
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.997 0.003
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.997 0.003
M07.18 Arthritis mutilans (Other)
0.000 0.997 0.003
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.997 0.003
M07.16 Arthritis mutilans (Lower leg)
0.000 0.997 0.003
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.997 0.003
M07.14 Arthritis mutilans (Hand)
0.000 0.997 0.003
M07.13 Arthritis mutilans (Forearm)
0.000 0.997 0.003
M07.12 Arthritis mutilans (Upper arm)
0.000 0.997 0.003
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.997 0.003
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.997 0.003
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.997 0.003
M07.28 Psoriatic spondylitis (Other)
0.000 0.997 0.003
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.997 0.003
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.997 0.003
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.997 0.003
M07.24 Psoriatic spondylitis (Hand)
0.000 0.997 0.003
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.997 0.003
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.997 0.003
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.997 0.003
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.997 0.003
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.997 0.003
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.997 0.003
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.997 0.003
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.997 0.003
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.997 0.003
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.000 0.997 0.003
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.000 0.997 0.003
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.000 0.997 0.003
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.000 0.997 0.003
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.000 0.997 0.003
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.000 0.997 0.003
M07.58 Arthropathy in ulcerative colitis (Other)
0.000 0.997 0.003
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.000 0.997 0.003
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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