TreeWAS – Variant ID: rs4669226

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65-H75 Diseases of middle ear and mastoid	0.924	0.076	0.000
H73 Other disorders of tympanic membrane	0.915	0.085	0.000
H65 Nonsuppurative otitis media	0.913	0.087	0.000
H73.8 Other specified disorders of tympanic membrane	0.908	0.092	0.000
H72 Perforation of tympanic membrane	0.885	0.115	0.000
H65.3 Chronic mucoid otitis media	0.866	0.134	0.000
H71 Cholesteatoma of middle ear	0.865	0.135	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.860	0.140	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.830	0.170	0.000
H72.8 Other perforations of tympanic membrane	0.755	0.245	0.000
H69 Other disorders of Eustachian tube	0.712	0.288	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.699	0.301	0.000
H66 Suppurative and unspecified otitis media	0.696	0.304	0.000
H72.1 Attic perforation of tympanic membrane	0.693	0.307	0.000
H70 Mastoiditis and related conditions	0.687	0.313	0.000
H65.2 Chronic serous otitis media	0.679	0.321	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.663	0.337	0.000
H68 Eustachian salpingitis and obstruction	0.663	0.337	0.000
H67 Otitis media in diseases classified elsewhere	0.663	0.337	0.000
H65.4 Other chronic nonsuppurative otitis media	0.661	0.339	0.000
Chapter VIII Diseases of the ear and mastoid process	0.658	0.342	0.000
H73.1 Chronic myringitis	0.656	0.344	0.000
H73.0 Acute myringitis	0.656	0.344	0.000
H65.1 Other acute nonsuppurative otitis media	0.654	0.345	0.000
H65.0 Acute serous otitis media	0.654	0.345	0.000
H72.2 Other marginal perforations of tympanic membrane	0.634	0.365	0.000
H90-H95 Other disorders of ear	0.627	0.373	0.000
H74 Other disorders of middle ear and mastoid	0.620	0.380	0.000
H92 Otalgia and effusion of ear	0.591	0.409	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.577	0.423	0.000
H72.0 Central perforation of tympanic membrane	0.564	0.436	0.000
H92.0 Otalgia	0.552	0.448	0.000
H69.9 Eustachian tube disorder, unspecified	0.548	0.452	0.000
H69.8 Other specified disorders of Eustachian tube	0.524	0.475	0.000
H70.9 Mastoiditis, unspecified	0.517	0.483	0.000
H66.9 Otitis media, unspecified	0.515	0.485	0.000
H90 Conductive and sensorineural hearing loss	0.513	0.487	0.000
H91 Other hearing loss	0.512	0.488	0.000
H69.0 Patulous Eustachian tube	0.510	0.490	0.000
H66.4 Suppurative otitis media, unspecified	0.499	0.501	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.499	0.501	0.000
H66.0 Acute suppurative otitis media	0.499	0.501	0.000
H70.8 Other mastoiditis and related conditions	0.492	0.507	0.000
H70.2 Petrositis	0.492	0.507	0.000
H70.1 Chronic mastoiditis	0.492	0.507	0.000
H70.0 Acute mastoiditis	0.492	0.507	0.000
H92.1 Otorrhoea	0.482	0.517	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.475	0.525	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.475	0.525	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.475	0.525	0.000
H68.1 Obstruction of Eustachian tube	0.475	0.525	0.000
H68.0 Eustachian salpingitis	0.475	0.525	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.475	0.525	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.475	0.525	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.472	0.528	0.000
H74.4 Polyp of middle ear	0.471	0.529	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.449	0.550	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.444	0.555	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.444	0.555	0.000
H74.1 Adhesive middle ear disease	0.444	0.555	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.444	0.556	0.000
H80-H83 Diseases of inner ear	0.438	0.562	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.434	0.566	0.000
H91.9 Hearing loss, unspecified	0.431	0.569	0.000
H92.2 Otorrhagia	0.424	0.576	0.000
H74.0 Tympanosclerosis	0.415	0.585	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.412	0.588	0.000
H66.3 Other chronic suppurative otitis media	0.403	0.597	0.000
H60-H62 Diseases of external ear	0.386	0.614	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.368	0.632	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.368	0.632	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.367	0.632	0.000
H91.3 Deaf mutism, not elsewhere classified	0.367	0.632	0.000
H91.2 Sudden idiopathic hearing loss	0.367	0.632	0.000
H91.1 Presbycusis	0.367	0.632	0.000
H91.0 Ototoxic hearing loss	0.367	0.632	0.000
H91.8 Other specified hearing loss	0.367	0.633	0.000
H93 Other disorders of ear, not elsewhere classified	0.367	0.633	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.365	0.635	0.000
H90.3 Sensorineural hearing loss, bilateral	0.350	0.650	0.000
H90.0 Conductive hearing loss, bilateral	0.341	0.659	0.000
H80 Otosclerosis	0.338	0.662	0.000
H90.5 Sensorineural hearing loss, unspecified	0.337	0.662	0.000
H90.2 Conductive hearing loss, unspecified	0.334	0.666	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.322	0.677	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.322	0.677	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.318	0.681	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.318	0.681	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.318	0.681	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.314	0.686	0.000
H95.1 Other disorders following mastoidectomy	0.313	0.687	0.000
H83 Other diseases of inner ear	0.283	0.717	0.000
H81 Disorders of vestibular function	0.283	0.717	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.277	0.723	0.000
H60 Otitis externa	0.275	0.725	0.000
H80.9 Otosclerosis, unspecified	0.266	0.734	0.000
H93.9 Disorder of ear, unspecified	0.263	0.737	0.000
H93.8 Other specified disorders of ear	0.263	0.737	0.000
H93.3 Disorders of acoustic nerve	0.263	0.737	0.000
H93.2 Other abnormal auditory perceptions	0.263	0.737	0.000
H93.0 Degenerative and vascular disorders of ear	0.263	0.737	0.000
H80.8 Other otosclerosis	0.242	0.758	0.000
H80.2 Cochlear otosclerosis	0.242	0.758	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.242	0.758	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.242	0.758	0.000
H81.1 Benign paroxysmal vertigo	0.230	0.770	0.000
H60.3 Other infective otitis externa	0.215	0.785	0.000
H60.8 Other otitis externa	0.212	0.788	0.000
H83.9 Disease of inner ear, unspecified	0.203	0.797	0.000
H83.8 Other specified diseases of inner ear	0.203	0.797	0.000
H83.3 Noise effects on inner ear	0.203	0.797	0.000
H83.2 Labyrinthine dysfunction	0.203	0.797	0.000
H83.1 Labyrinthine fistula	0.203	0.797	0.000
H81.9 Disorder of vestibular function, unspecified	0.203	0.797	0.000
H81.8 Other disorders of vestibular function	0.203	0.797	0.000
H81.4 Vertigo of central origin	0.203	0.797	0.000
H81.3 Other peripheral vertigo	0.203	0.797	0.000
H81.2 Vestibular neuronitis	0.202	0.798	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.199	0.801	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.199	0.801	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.199	0.801	0.000
H62.2 Otitis externa in mycoses	0.199	0.801	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.199	0.801	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.199	0.801	0.000
H60.5 Acute otitis externa, non-infective	0.197	0.802	0.000
H60.4 Cholesteatoma of external ear	0.197	0.802	0.000
H60.2 Malignant otitis externa	0.197	0.802	0.000
H60.0 Abscess of external ear	0.197	0.802	0.000
H61 Other disorders of external ear	0.194	0.806	0.000
H60.1 Cellulitis of external ear	0.181	0.819	0.000
H93.1 Tinnitus	0.180	0.819	0.000
H83.0 Labyrinthitis	0.172	0.828	0.000
H60.9 Otitis externa, unspecified	0.172	0.828	0.000
H61.8 Other specified disorders of external ear	0.147	0.853	0.000
H61.9 Disorder of external ear, unspecified	0.138	0.861	0.000
H61.3 Acquired stenosis of external ear canal	0.134	0.865	0.000
H61.2 Impacted cerumen	0.134	0.866	0.000
H61.1 Non-infective disorders of pinna	0.125	0.875	0.000
H81.0 Meniere's disease	0.116	0.884	0.000
H61.0 Perichondritis of external ear	0.090	0.910	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.027	0.973	0.000
R51 Headache	0.016	0.984	0.000
Y95 Nosocomial condition	0.000	0.987	0.013
H40.1 Primary open-angle glaucoma	0.010	0.990	0.000
H40.2 Primary angle-closure glaucoma	0.009	0.991	0.000
H40 Glaucoma	0.009	0.991	0.000
J40 Bronchitis, not specified as acute or chronic	0.000	0.991	0.009
H40.9 Glaucoma, unspecified	0.009	0.991	0.000
H40.3 Glaucoma secondary to eye trauma	0.008	0.992	0.000
H40.5 Glaucoma secondary to other eye disorders	0.007	0.993	0.000
H40.6 Glaucoma secondary to drugs	0.007	0.993	0.000
H40.4 Glaucoma secondary to eye inflammation	0.007	0.993	0.000
D64.9 Anaemia, unspecified	0.000	0.994	0.006
H40.8 Other glaucoma	0.005	0.994	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.000	0.994	0.006
M19.94 Arthrosis, unspecified (Hand)	0.000	0.994	0.006
K86.1 Other chronic pancreatitis	0.000	0.995	0.005
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.000	0.996	0.004
Y98 Lifestyle-related condition	0.000	0.996	0.004
Y97 Environmental-pollution-related condition	0.000	0.996	0.004
Y96 Work-related condition	0.000	0.996	0.004
Y91 Evidence of alcohol involvement determined by level of intoxication	0.000	0.996	0.004
H40.0 Glaucoma suspect	0.004	0.996	0.000
D64 Other anaemias	0.000	0.996	0.004
H40-H42 Glaucoma	0.004	0.996	0.000
Y90.9 Presence of alcohol in blood, level not specified	0.000	0.997	0.003
Y90.8 Blood alcohol level of 240 mg/100 ml or more	0.000	0.997	0.003
Y90.7 Blood alcohol level of 200-239 mg/100 ml	0.000	0.997	0.003
Y90.6 Blood alcohol level of 120-199 mg/100 ml	0.000	0.997	0.003
Y90.5 Blood alcohol level of 100-119 mg/100 ml	0.000	0.997	0.003
Y90.4 Blood alcohol level of 80-99 mg/100 ml	0.000	0.997	0.003
Y90.3 Blood alcohol level of 60-79 mg/100 ml	0.000	0.997	0.003
Y90.2 Blood alcohol level of 40-59 mg/100 ml	0.000	0.997	0.003
Y90.1 Blood alcohol level of 20-39 mg/100 ml	0.000	0.997	0.003
Y90.0 Blood alcohol level of less than 20 mg/100 ml	0.000	0.997	0.003
Y91.3 Very severe alcohol intoxication	0.000	0.997	0.003
Y91.2 Severe alcohol intoxication	0.000	0.997	0.003
Y91.1 Moderate alcohol intoxication	0.000	0.997	0.003
Y91.0 Mild alcohol intoxication	0.000	0.997	0.003
D61.9 Aplastic anaemia, unspecified	0.000	0.997	0.003
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.997	0.003
D64.8 Other specified anaemias	0.000	0.997	0.003
D64.4 Congenital dyserythropoietic anaemia	0.000	0.997	0.003
D64.3 Other sideroblastic anaemias	0.000	0.997	0.003
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.997	0.003
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.997	0.003
D64.0 Hereditary sideroblastic anaemia	0.000	0.997	0.003
H42 Glaucoma in diseases classified elsewhere	0.003	0.997	0.000
K86.3 Pseudocyst of pancreas	0.000	0.997	0.003
K86 Other diseases of pancreas	0.000	0.997	0.003
D61 Other aplastic anaemias	0.000	0.997	0.003
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.997	0.003
L30.9 Dermatitis, unspecified	0.003	0.997	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.000	0.997	0.003
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.997	0.003
D60-D64 Aplastic and other anaemias	0.000	0.997	0.003
I72.3 Aneurysm of iliac artery	0.003	0.997	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.997	0.003
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.997	0.003
K86.2 Cyst of pancreas	0.000	0.997	0.003
H42.8 Glaucoma in other diseases classified elsewhere	0.002	0.997	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.002	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
D61.8 Other specified aplastic anaemias	0.000	0.998	0.002
D61.3 Idiopathic aplastic anaemia	0.000	0.998	0.002
D61.2 Aplastic anaemia due to other external agents	0.000	0.998	0.002
D61.1 Drug-induced aplastic anaemia	0.000	0.998	0.002
D61.0 Constitutional aplastic anaemia	0.000	0.998	0.002
L30 Other dermatitis	0.002	0.998	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.998	0.002
J84 Other interstitial pulmonary diseases	0.000	0.998	0.002
L29 Pruritus	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.000
L29.0 Pruritus ani	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
L29.2 Pruritus vulvae	0.002	0.998	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
L29.8 Other pruritus	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
N80.9 Endometriosis, unspecified	0.002	0.998	0.000
L28 Lichen simplex chronicus and prurigo	0.002	0.998	0.000
L30.5 Pityriasis alba	0.002	0.998	0.000
L30.4 Erythema intertrigo	0.002	0.998	0.000
L30.3 Infective dermatitis	0.002	0.998	0.000
L30.2 Cutaneous autosensitisation	0.002	0.998	0.000
L30.1 Dyshidrosis [pompholyx]	0.002	0.998	0.000
L30.0 Nummular dermatitis	0.002	0.998	0.000
L30.8 Other specified dermatitis	0.002	0.998	0.000
L28.1 Prurigo nodularis	0.002	0.998	0.000
L20-L30 Dermatitis and eczema	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.998	0.002
D60.8 Other acquired pure red cell aplasias	0.000	0.998	0.002
D60.1 Transient acquired pure red cell aplasia	0.000	0.998	0.002
D60.0 Chronic acquired pure red cell aplasia	0.000	0.998	0.002
J81 Pulmonary oedema	0.000	0.998	0.002
J84.0 Alveolar and parietoalveolar conditions	0.000	0.998	0.002
L29.3 Anogenital pruritus, unspecified	0.002	0.998	0.000
L29.1 Pruritus scroti	0.002	0.998	0.000
Z13.1 Special screening examination for diabetes mellitus	0.000	0.998	0.002
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.998	0.002
L29.9 Pruritus, unspecified	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.000	0.998	0.002
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.998	0.002
J84.8 Other specified interstitial pulmonary diseases	0.000	0.998	0.002
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
K86.8 Other specified diseases of pancreas	0.000	0.998	0.002
L21 Seborrhoeic dermatitis	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
K14.8 Other diseases of tongue	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
L28.2 Other prurigo	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.002	0.998	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.002	0.998	0.000
L25 Unspecified contact dermatitis	0.002	0.998	0.000
L24 Irritant contact dermatitis	0.002	0.998	0.000
L23 Allergic contact dermatitis	0.002	0.998	0.000
L26 Exfoliative dermatitis	0.002	0.998	0.000
L22 Diaper [napkin] dermatitis	0.002	0.998	0.000
Z13 Special screening examination for other diseases and disorders	0.000	0.998	0.002
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
D50.9 Iron deficiency anaemia, unspecified	0.000	0.998	0.002
L21.9 Seborrhoeic dermatitis, unspecified	0.001	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.002	0.998	0.000
Z13.9 Special screening examination, unspecified	0.000	0.998	0.002
L20 Atopic dermatitis	0.001	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
J45.0 Predominantly allergic asthma	0.000	0.998	0.002
L21.8 Other seborrhoeic dermatitis	0.001	0.998	0.000
L21.1 Seborrhoeic infantile dermatitis	0.001	0.998	0.000
L21.0 Seborrhoea capitis	0.001	0.998	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.998	0.001
D86.8 Sarcoidosis of other and combined sites	0.001	0.998	0.000
H26.8 Other specified cataract	0.000	0.998	0.002
J94.2 Haemothorax	0.001	0.998	0.000
M75.1 Rotator cuff syndrome	0.002	0.998	0.000
Z13.3 Special screening examination for mental and behavioural disorders	0.000	0.998	0.001
C49 Malignant neoplasm of other connective and soft tissue	0.001	0.998	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.001	0.998	0.000
L23.8 Allergic contact dermatitis due to other agents	0.001	0.998	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.001	0.998	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.001	0.998	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.001	0.998	0.000
L23.4 Allergic contact dermatitis due to dyes	0.001	0.998	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.001	0.998	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.001	0.998	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.001	0.998	0.000
L23.0 Allergic contact dermatitis due to metals	0.001	0.998	0.000
L24.9 Irritant contact dermatitis, unspecified cause	0.001	0.998	0.000
L24.8 Irritant contact dermatitis due to other agents	0.001	0.998	0.000
L24.7 Irritant contact dermatitis due to plants, except food	0.001	0.998	0.000
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.001	0.998	0.000
L24.5 Irritant contact dermatitis due to other chemical products	0.001	0.998	0.000
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.001	0.998	0.000
L24.3 Irritant contact dermatitis due to cosmetics	0.001	0.998	0.000
L24.2 Irritant contact dermatitis due to solvents	0.001	0.998	0.000
L24.1 Irritant contact dermatitis due to oils and greases	0.001	0.998	0.000
L24.0 Irritant contact dermatitis due to detergents	0.001	0.998	0.000
L25.9 Unspecified contact dermatitis, unspecified cause	0.001	0.998	0.000
L25.8 Unspecified contact dermatitis due to other agents	0.001	0.998	0.000
L25.5 Unspecified contact dermatitis due to plants, except food	0.001	0.998	0.000
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.001	0.998	0.000
L25.3 Unspecified contact dermatitis due to other chemical products	0.001	0.998	0.000
L25.2 Unspecified contact dermatitis due to dyes	0.001	0.998	0.000
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.001	0.998	0.000
L25.0 Unspecified contact dermatitis due to cosmetics	0.001	0.998	0.000
Z13.8 Special screening examination for other specified diseases and disorders	0.000	0.999	0.001
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.000	0.999	0.001
Z13.4 Special screening examination for certain developmental disorders in childhood	0.000	0.999	0.001
Z13.2 Special screening examination for nutritional disorders	0.000	0.999	0.001
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.999	0.001
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.999	0.001
L20.8 Other atopic dermatitis	0.001	0.999	0.000
L20.0 Besnier's prurigo	0.001	0.999	0.000
D86 Sarcoidosis	0.001	0.999	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.001	0.999	0.000
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.001	0.999	0.000
L27 Dermatitis due to substances taken internally	0.001	0.999	0.000
C49.3 Connective and soft tissue of thorax	0.001	0.999	0.000
S02.6 Fracture of mandible	0.001	0.999	0.000
C45.7 Mesothelioma of other sites	0.001	0.999	0.000
Q21.1 Atrial septal defect	0.000	0.999	0.001
G12.2 Motor neuron disease	0.001	0.999	0.000
C49.9 Connective and soft tissue, unspecified	0.001	0.999	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.001	0.999	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.001	0.999	0.000
C49.5 Connective and soft tissue of pelvis	0.001	0.999	0.000
C49.4 Connective and soft tissue of abdomen	0.001	0.999	0.000
L20.9 Atopic dermatitis, unspecified	0.001	0.999	0.000
J03 Acute tonsillitis	0.000	0.999	0.001
Z13.83 Encounter for screening for respiratory disorder NEC	0.000	0.999	0.001
Z13.82 Encounter for screening for musculoskeletal disorder	0.000	0.999	0.001
H54.9 Unspecified visual impairment (binocular)	0.001	0.999	0.000
I72.0 Aneurysm of carotid artery	0.001	0.999	0.000
K14.0 Glossitis	0.000	0.999	0.001
M23.2 Derangement of meniscus due to old tear or injury	0.001	0.999	0.000
Z13.5 Special screening examination for eye and ear disorders	0.000	0.999	0.001
C45 Mesothelioma	0.001	0.999	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.999	0.001
C45.9 Mesothelioma, unspecified	0.001	0.999	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.999	0.001
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
E07.8 Other specified disorders of thyroid	0.001	0.999	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.001	0.999	0.000
L27.8 Dermatitis due to other substances taken internally	0.001	0.999	0.000
L27.2 Dermatitis due to ingested food	0.001	0.999	0.000
C45.0 Mesothelioma of pleura	0.001	0.999	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.001	0.999	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.001	0.999	0.000
S02.61 Fracture of mandible (open)	0.001	0.999	0.000
J86.0 Pyothorax with fistula	0.001	0.999	0.000
M22.4 Chondromalacia patellae	0.000	0.999	0.001
I72 Other aneurysm	0.001	0.999	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.001	0.999	0.000
C48.0 Retroperitoneum	0.001	0.999	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.001	0.999	0.000
Y40.0 Penicillins	0.001	0.999	0.000
E07 Other disorders of thyroid	0.001	0.999	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
S92.30 Fracture of metatarsal bone (closed)	0.001	0.999	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.000	0.999	0.001
J03.0 Streptococcal tonsillitis	0.000	0.999	0.001
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.001	0.999	0.000
K75.0 Abscess of liver	0.001	0.999	0.000
M19.9 Arthrosis, unspecified	0.000	0.999	0.001
O02.1 Missed abortion	0.000	0.999	0.001
X63.0 Home	0.001	0.999	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.001	0.999	0.000
C45.2 Mesothelioma of pericardium	0.001	0.999	0.000
C45.1 Mesothelioma of peritoneum	0.001	0.999	0.000
I72.9 Aneurysm of unspecified site	0.001	0.999	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.999	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.999	0.000
I72.2 Aneurysm of renal artery	0.001	0.999	0.000
I72.1 Aneurysm of artery of upper extremity	0.001	0.999	0.000
A41.8 Other specified septicaemia	0.000	0.999	0.001
E07.1 Dyshormogenetic goitre	0.001	0.999	0.000
E07.0 Hypersecretion of calcitonin	0.001	0.999	0.000
H54.0 Blindness, both eyes	0.001	0.999	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.001	0.999	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
S81.9 Open wound of lower leg, part unspecified	0.001	0.999	0.000
Y46.2 Hydantoin derivatives	0.001	0.999	0.000
J91 Pleural effusion in conditions classified elsewhere	0.000	0.999	0.001
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.999	0.001
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.001	0.999	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.001	0.999	0.000
S09.9 Unspecified injury of head	0.001	0.999	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.001	0.999	0.000
M89.98 Disorder of bone, unspecified (Other)	0.001	0.999	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.999	0.001
I72.4 Aneurysm of artery of lower extremity	0.001	0.999	0.000
Z04.9 Examination and observation for unspecified reason	0.001	0.999	0.000
Z04.3 Examination and observation following other accident	0.001	0.999	0.000
A41 Other septicaemia	0.000	0.999	0.001
K14 Diseases of tongue	0.000	0.999	0.001
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.001	0.999	0.000
S92.3 Fracture of metatarsal bone	0.001	0.999	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.001	0.999	0.000
R32 Unspecified urinary incontinence	0.000	0.999	0.001
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.001	0.999	0.000
M19.98 Arthrosis, unspecified (Other)	0.000	0.999	0.001
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.999	0.001
S02.80 Fractures of other skull and facial bones (closed)	0.001	0.999	0.000
H54.7 Unspecified visual loss	0.001	0.999	0.000
I72.8 Aneurysm of other specified arteries	0.001	0.999	0.000
J94.8 Other specified pleural conditions	0.001	0.999	0.000
K14.6 Glossodynia	0.000	0.999	0.001
K14.5 Plicated tongue	0.000	0.999	0.001
K14.4 Atrophy of tongue papillae	0.000	0.999	0.001
K14.3 Hypertrophy of tongue papillae	0.000	0.999	0.001
K14.2 Median rhomboid glossitis	0.000	0.999	0.001
K14.1 Geographic tongue	0.000	0.999	0.001
S02.8 Fractures of other skull and facial bones	0.001	0.999	0.000
S02 Fracture of skull and facial bones	0.001	0.999	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
A41.4 Septicaemia due to anaerobes	0.000	0.999	0.001
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.999	0.001
C53.9 Cervix uteri, unspecified	0.001	0.999	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.999	0.001
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.001	0.999	0.000
C46 Kaposi's sarcoma	0.001	0.999	0.000
H54 Blindness and low vision	0.001	0.999	0.000
S80 Superficial injury of lower leg	0.001	0.999	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
S02.81 Fractures of other skull and facial bones (open)	0.001	0.999	0.000
C48.1 Specified parts of peritoneum	0.001	0.999	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.001	0.999	0.000
M19.0 Primary arthrosis of other joints	0.000	0.999	0.001
M25.6 Stiffness of joint, not elsewhere classified	0.001	0.999	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.001	0.999	0.000
S02.7 Multiple fractures involving skull and facial bones	0.001	0.999	0.000
S02.3 Fracture of orbital floor	0.001	0.999	0.000
S02.1 Fracture of base of skull	0.001	0.999	0.000
S80.7 Multiple superficial injuries of lower leg	0.001	0.999	0.000
S80.0 Contusion of knee	0.001	0.999	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.999	0.001
J94 Other pleural conditions	0.001	0.999	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.999	0.001
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.999	0.001
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.999	0.001
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.999	0.001
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.999	0.001
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.001	0.999	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
S02.11 Fracture of base of skull (open)	0.001	0.999	0.000
S02.31 Fracture of orbital floor (open)	0.001	0.999	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.001	0.999	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.001	0.999	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.001	0.999	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.999	0.001
C46.9 Kaposi's sarcoma, unspecified	0.001	0.999	0.000
C46.8 Kaposi's sarcoma of multiple organs	0.001	0.999	0.000
C46.7 Kaposi's sarcoma of other sites	0.001	0.999	0.000
C46.3 Kaposi's sarcoma of lymph nodes	0.001	0.999	0.000
C46.2 Kaposi's sarcoma of palate	0.001	0.999	0.000
C46.1 Kaposi's sarcoma of soft tissue	0.001	0.999	0.000
C46.0 Kaposi's sarcoma of skin	0.001	0.999	0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.001	0.999	0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.001	0.999	0.000
C47.6 Peripheral nerves of trunk, unspecified	0.001	0.999	0.000
C47.5 Peripheral nerves of pelvis	0.001	0.999	0.000
C47.4 Peripheral nerves of abdomen	0.001	0.999	0.000
C47.3 Peripheral nerves of thorax	0.001	0.999	0.000
C47.2 Peripheral nerves of lower limb, including hip	0.001	0.999	0.000
C47.1 Peripheral nerves of upper limb, including shoulder	0.001	0.999	0.000
C47.0 Peripheral nerves of head, face and neck	0.001	0.999	0.000
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
H54.5 Low vision, one eye	0.001	0.999	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.999	0.000
H54.2 Low vision, both eyes	0.001	0.999	0.000
H54.1 Blindness, one eye, low vision, other eye	0.001	0.999	0.000
J94.9 Pleural condition, unspecified	0.001	0.999	0.000
J94.1 Fibrothorax	0.001	0.999	0.000
J94.0 Chylous effusion	0.001	0.999	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.001	0.999	0.000
M23.5 Chronic instability of knee	0.001	0.999	0.000
J00 Acute nasopharyngitis [common cold]	0.000	0.999	0.001
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.999	0.001
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations