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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs494558
log Bayes Factor = 2.91881
Chromosome 13   position 110,929,162  (GRCh37) Explore rs494558 on Ensembl!
Variant rs494558 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
I20-I25 Ischaemic heart diseases
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.968 0.032 0.000
I20 Angina pectoris
0.959 0.041 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.936 0.064 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.922 0.078 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.920 0.080 0.000
Chapter XXI Factors influencing health status and contact with health services
0.920 0.080 0.000
E70-E90 Metabolic disorders
0.915 0.085 0.000
I25 Chronic ischaemic heart disease
0.914 0.086 0.000
I20.9 Angina pectoris, unspecified
0.912 0.088 0.000
R50-R69 General symptoms and signs
0.909 0.091 0.000
Chapter V Mental and behavioural disorders
0.907 0.093 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.905 0.095 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.898 0.102 0.000
R30-R39 Symptoms and signs involving the urinary system
0.895 0.105 0.000
E78.0 Pure hypercholesterolaemia
0.891 0.109 0.000
Z86 Personal history of certain other diseases
0.868 0.132 0.000
Z92 Personal history of medical treatment
0.863 0.137 0.000
E65-E68 Obesity and other hyperalimentation
0.841 0.159 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.838 0.162 0.000
M20-M25 Other joint disorders
0.838 0.162 0.000
I25.1 Atherosclerotic heart disease
0.835 0.165 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.833 0.167 0.000
R10 Abdominal and pelvic pain
0.831 0.169 0.000
I20.0 Unstable angina
0.823 0.176 0.000
I21 Acute myocardial infarction
0.809 0.191 0.000
I60-I69 Cerebrovascular diseases
0.796 0.204 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.794 0.205 0.000
R31 Unspecified haematuria
0.794 0.206 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.791 0.209 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.789 0.211 0.000
L60-L75 Disorders of skin appendages
0.782 0.218 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.779 0.220 0.000
Chapter I Certain infectious and parasitic diseases
0.778 0.222 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.775 0.225 0.000
R11 Nausea and vomiting
0.773 0.227 0.000
Chapter XX External causes of morbidity and mortality
0.773 0.227 0.000
M15-M19 Arthrosis
0.772 0.228 0.000
E10-E14 Diabetes mellitus
0.771 0.229 0.000
R13 Dysphagia
0.769 0.231 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.763 0.237 0.000
R69 Unknown and unspecified causes of morbidity
0.763 0.237 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.761 0.239 0.000
Chapter VII Diseases of the eye and adnexa
0.758 0.242 0.000
I30-I52 Other forms of heart disease
0.758 0.242 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.756 0.244 0.000
Z86.7 Personal history of diseases of the circulatory system
0.749 0.251 0.000
E66 Obesity
0.747 0.253 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.744 0.256 0.000
I22 Subsequent myocardial infarction
0.737 0.263 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.736 0.264 0.000
R51 Headache
0.733 0.267 0.000
R15 Faecal incontinence
0.728 0.272 0.000
R47-R49 Symptoms and signs involving speech and voice
0.727 0.273 0.000
M45-M49 Spondylopathies
0.726 0.274 0.000
Z86.0 Personal history of other neoplasms
0.726 0.274 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.725 0.275 0.000
I10-I15 Hypertensive diseases
0.721 0.279 0.000
R10.3 Pain localised to other parts of lower abdomen
0.719 0.281 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.717 0.283 0.000
L20-L30 Dermatitis and eczema
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
M70-M79 Other soft tissue disorders
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
Chapter XXII Codes for special purposes
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
I23 Certain current complications following acute myocardial infarction
0.710 0.290 0.000
Z83 Family history of other specific disorders
0.710 0.290 0.000
F30-F39 Mood [affective] disorders
0.708 0.292 0.000
R33 Retention of urine
0.708 0.292 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.708 0.292 0.000
R32 Unspecified urinary incontinence
0.706 0.294 0.000
I20.8 Other forms of angina pectoris
0.705 0.295 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.702 0.298 0.000
I24 Other acute ischaemic heart diseases
0.701 0.298 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.701 0.299 0.000
E20-E35 Disorders of other endocrine glands
0.700 0.300 0.000
M50-M54 Other dorsopathies
0.700 0.300 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.700 0.300 0.000
I20.1 Angina pectoris with documented spasm
0.699 0.301 0.000
E00-E07 Disorders of thyroid gland
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.691 0.309 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.690 0.310 0.000
Z97 Presence of other devices
0.688 0.312 0.000
M25 Other joint disorders, not elsewhere classified
0.688 0.312 0.000
R56 Convulsions, not elsewhere classified
0.687 0.313 0.000
M60-M63 Disorders of muscles
0.686 0.314 0.000
R10.1 Pain localised to upper abdomen
0.686 0.314 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.683 0.316 0.000
I25.2 Old myocardial infarction
0.683 0.317 0.000
L82 Seborrhoeic keratosis
0.682 0.318 0.000
E83 Disorders of mineral metabolism
0.681 0.319 0.000
R63 Symptoms and signs concerning food and fluid intake
0.681 0.319 0.000
E66.9 Obesity, unspecified
0.681 0.319 0.000
E40-E46 Malnutrition
0.680 0.320 0.000
R07 Pain in throat and chest
0.680 0.320 0.000
I05-I09 Chronic rheumatic heart diseases
0.679 0.320 0.000
R17 Unspecified jaundice
0.679 0.321 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.678 0.321 0.000
E50-E64 Other nutritional deficiencies
0.677 0.323 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.676 0.324 0.000
M86-M90 Other osteopathies
0.675 0.325 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.674 0.326 0.000
R50 Fever of unknown origin
0.673 0.327 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.673 0.327 0.000
M40-M43 Deforming dorsopathies
0.672 0.328 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.672 0.328 0.000
R14 Flatulence and related conditions
0.670 0.330 0.000
R52 Pain, not elsewhere classified
0.670 0.330 0.000
Z89 Acquired absence of limb
0.669 0.331 0.000
Chapter II Neoplasms
0.669 0.331 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.669 0.331 0.000
F41 Other anxiety disorders
0.667 0.333 0.000
R55 Syncope and collapse
0.667 0.333 0.000
R53 Malaise and fatigue
0.667 0.333 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.666 0.334 0.000
R68 Other general symptoms and signs
0.666 0.334 0.000
Z87 Personal history of other diseases and conditions
0.666 0.334 0.000
I25.5 Ischaemic cardiomyopathy
0.666 0.334 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.665 0.335 0.000
L10-L14 Bullous disorders
0.664 0.336 0.000
Z92.3 Personal history of irradiation
0.664 0.336 0.000
L40-L45 Papulosquamous disorders
0.663 0.337 0.000
Chapter X Diseases of the respiratory system
0.663 0.337 0.000
L50-L54 Urticaria and erythema
0.662 0.338 0.000
E85 Amyloidosis
0.662 0.338 0.000
I25.3 Aneurysm of heart
0.662 0.338 0.000
E73 Lactose intolerance
0.659 0.340 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.659 0.341 0.000
F80-F89 Disorders of psychological development
0.659 0.341 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.659 0.341 0.000
I25.4 Coronary artery aneurysm
0.658 0.342 0.000
R60 Oedema, not elsewhere classified
0.658 0.342 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.657 0.343 0.000
M80-M85 Disorders of bone density and structure
0.657 0.343 0.000
E79 Disorders of purine and pyrimidine metabolism
0.657 0.343 0.000
E72 Other disorders of amino-acid metabolism
0.657 0.343 0.000
R58 Haemorrhage, not elsewhere classified
0.657 0.343 0.000
E70 Disorders of aromatic amino-acid metabolism
0.656 0.343 0.000
E77 Disorders of glycoprotein metabolism
0.656 0.344 0.000
E76 Disorders of glycosaminoglycan metabolism
0.656 0.344 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.656 0.344 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.656 0.344 0.000
I25.6 Silent myocardial ischaemia
0.656 0.344 0.000
R61 Hyperhidrosis
0.655 0.345 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.655 0.345 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.654 0.346 0.000
R64 Cachexia
0.654 0.346 0.000
E11 Non-insulin-dependent diabetes mellitus
0.654 0.346 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.654 0.346 0.000
Z94 Transplanted organ and tissue status
0.653 0.347 0.000
R62 Lack of expected normal physiological development
0.652 0.348 0.000
F70-F79 Mental retardation
0.651 0.348 0.000
F60-F69 Disorders of adult personality and behaviour
0.651 0.349 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.651 0.349 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.651 0.349 0.000
M91-M94 Chondropathies
0.650 0.350 0.000
E78.8 Other disorders of lipoprotein metabolism
0.649 0.350 0.000
E88 Other metabolic disorders
0.649 0.350 0.000
R30 Pain associated with micturition
0.649 0.351 0.000
M00-M03 Infectious arthropathies
0.649 0.351 0.000
M65-M68 Disorders of synovium and tendon
0.649 0.351 0.000
R54 Senility
0.648 0.352 0.000
S50-S59 Injuries to the elbow and forearm
0.647 0.353 0.000
R34 Anuria and oliguria
0.647 0.353 0.000
I21.9 Acute myocardial infarction, unspecified
0.647 0.353 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.647 0.353 0.000
M24 Other specific joint derangements
0.646 0.354 0.000
S60-S69 Injuries to the wrist and hand
0.646 0.354 0.000
E78.6 Lipoprotein deficiency
0.645 0.355 0.000
E78.3 Hyperchylomicronaemia
0.644 0.355 0.000
M35 Other systemic involvement of connective tissue
0.644 0.356 0.000
R36 Urethral discharge
0.644 0.356 0.000
R57 Shock, not elsewhere classified
0.643 0.357 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.643 0.357 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.643 0.357 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.641 0.359 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.640 0.359 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.640 0.360 0.000
E74 Other disorders of carbohydrate metabolism
0.639 0.360 0.000
F99-F99 Unspecified mental disorder
0.639 0.361 0.000
M05-M14 Inflammatory polyarthropathies
0.639 0.361 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.636 0.364 0.000
Z84 Family history of other conditions
0.636 0.364 0.000
Z81 Family history of mental and behavioural disorders
0.635 0.365 0.000
R12 Heartburn
0.635 0.365 0.000
M22 Disorders of patella
0.634 0.366 0.000
M19 Other arthrosis
0.633 0.367 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.632 0.368 0.000
R59 Enlarged lymph nodes
0.632 0.368 0.000
Z93 Artificial opening status
0.630 0.370 0.000
R35 Polyuria
0.629 0.371 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.629 0.371 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.627 0.373 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.626 0.374 0.000
E78.2 Mixed hyperlipidaemia
0.625 0.375 0.000
Z86.4 Personal history of psychoactive substance abuse
0.625 0.375 0.000
I63 Cerebral infarction
0.625 0.375 0.000
T66-T78 Other and unspecified effects of external causes
0.622 0.378 0.000
E78.4 Other hyperlipidaemia
0.621 0.379 0.000
M20 Acquired deformities of fingers and toes
0.621 0.379 0.000
E78.1 Pure hyperglyceridaemia
0.620 0.380 0.000
M21 Other acquired deformities of limbs
0.620 0.380 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.620 0.380 0.000
Chapter VIII Diseases of the ear and mastoid process
0.619 0.380 0.000
Z85 Personal history of malignant neoplasm
0.619 0.380 0.000
Z92.5 Personal history of rehabilitation measures
0.619 0.381 0.000
Z92.9 Personal history of medical treatment, unspecified
0.619 0.381 0.000
S10-S19 Injuries to the neck
0.619 0.381 0.000
E84 Cystic fibrosis
0.618 0.381 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.617 0.383 0.000
S40-S49 Injuries to the shoulder and upper arm
0.616 0.384 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.616 0.384 0.000
E86 Volume depletion
0.614 0.385 0.000
R04 Haemorrhage from respiratory passages
0.613 0.387 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.612 0.388 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.612 0.388 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.611 0.388 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.611 0.389 0.000
R10.0 Acute abdomen
0.611 0.389 0.000
S90-S99 Injuries to the ankle and foot
0.610 0.390 0.000
M34 Systemic sclerosis
0.609 0.390 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.609 0.391 0.000
S00-S09 Injuries to the head
0.608 0.392 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.607 0.393 0.000
E65 Localised adiposity
0.607 0.393 0.000
Z96 Presence of other functional implants
0.606 0.394 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.606 0.394 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.605 0.395 0.000
R10.4 Other and unspecified abdominal pain
0.605 0.395 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.604 0.396 0.000
M33 Dermatopolymyositis
0.604 0.396 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.604 0.396 0.000
M30 Polyarteritis nodosa and related conditions
0.604 0.396 0.000
M23 Internal derangement of knee
0.603 0.397 0.000
Z92.0 Personal history of contraception
0.603 0.397 0.000
M32 Systemic lupus erythematosus
0.603 0.397 0.000
S80-S89 Injuries to the knee and lower leg
0.603 0.397 0.000
E67 Other hyperalimentation
0.603 0.397 0.000
E68 Sequelae of hyperalimentation
0.603 0.397 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.602 0.398 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.601 0.398 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.601 0.399 0.000
M47 Spondylosis
0.601 0.399 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.601 0.399 0.000
T33-T35 Frostbite
0.601 0.399 0.000
Z92.8 Personal history of other medical treatment
0.600 0.400 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.598 0.402 0.000
I26 Pulmonary embolism
0.598 0.402 0.000
I61 Intracerebral haemorrhage
0.596 0.404 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.595 0.405 0.000
T00-T07 Injuries involving multiple body regions
0.594 0.406 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.594 0.406 0.000
Q60-Q64 Congenital malformations of the urinary system
0.593 0.407 0.000
S20-S29 Injuries to the thorax
0.592 0.408 0.000
Z98 Other postsurgical states
0.592 0.408 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.592 0.408 0.000
B35-B49 Mycoses
0.590 0.410 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.589 0.411 0.000
A30-A49 Other bacterial diseases
0.589 0.411 0.000
J40-J47 Chronic lower respiratory diseases
0.589 0.411 0.000
L89 Decubitus ulcer
0.589 0.411 0.000
R10.2 Pelvic and perineal pain
0.589 0.411 0.000
I42 Cardiomyopathy
0.589 0.411 0.000
T79-T79 Certain early complications of trauma
0.588 0.412 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.588 0.412 0.000
M31 Other necrotising vasculopathies
0.587 0.413 0.000
R39 Other symptoms and signs involving the urinary system
0.586 0.413 0.000
I60 Subarachnoid haemorrhage
0.586 0.413 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.586 0.414 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.585 0.415 0.000
I67 Other cerebrovascular diseases
0.584 0.416 0.000
I51 Complications and ill-defined descriptions of heart disease
0.584 0.416 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.584 0.416 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.583 0.417 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.583 0.417 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.583 0.417 0.000
I62 Other nontraumatic intracranial haemorrhage
0.582 0.418 0.000
M18 Arthrosis of first carpometacarpal joint
0.582 0.418 0.000
L60 Nail disorders
0.582 0.418 0.000
R40 Somnolence, stupor and coma
0.581 0.419 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.580 0.420 0.000
L84 Corns and callosities
0.579 0.420 0.000
H53-H54 Visual disturbances and blindness
0.579 0.421 0.000
R42 Dizziness and giddiness
0.578 0.421 0.000
R45 Symptoms and signs involving emotional state
0.578 0.422 0.000
R18 Ascites
0.578 0.422 0.000
B95-B98 Bacterial, viral and other infectious agents
0.577 0.423 0.000
O80-O84 Delivery
0.577 0.423 0.000
Q00-Q07 Congenital malformations of the nervous system
0.576 0.423 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.576 0.424 0.000
Q50-Q56 Congenital malformations of genital organs
0.575 0.424 0.000
H43-H45 Disorders of vitreous body and globe
0.575 0.424 0.000
E78.5 Hyperlipidaemia, unspecified
0.575 0.425 0.000
W00-W19 Falls
0.574 0.426 0.000
Q80-Q89 Other congenital malformations
0.573 0.426 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.573 0.426 0.000
F32 Depressive episode
0.573 0.427 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.572 0.428 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.572 0.428 0.000
R07.3 Other chest pain
0.572 0.428 0.000
B25-B34 Other viral diseases
0.572 0.428 0.000
I21.4 Acute subendocardial myocardial infarction
0.572 0.428 0.000
I46 Cardiac arrest
0.572 0.428 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.572 0.428 0.000
I71 Aortic aneurysm and dissection
0.572 0.428 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.571 0.428 0.000
S70-S79 Injuries to the hip and thigh
0.571 0.429 0.000
I74 Arterial embolism and thrombosis
0.571 0.429 0.000
L71 Rosacea
0.571 0.429 0.000
L83 Acanthosis nigricans
0.570 0.429 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.570 0.429 0.000
Q35-Q37 Cleft lip and cleft palate
0.570 0.430 0.000
L93 Lupus erythematosus
0.570 0.430 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.569 0.430 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.569 0.431 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.569 0.431 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.569 0.431 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.569 0.431 0.000
I50 Heart failure
0.569 0.431 0.000
L80 Vitiligo
0.569 0.431 0.000
F45 Somatoform disorders
0.569 0.431 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.568 0.431 0.000
I69 Sequelae of cerebrovascular disease
0.568 0.432 0.000
R02 Gangrene, not elsewhere classified
0.568 0.432 0.000
I44 Atrioventricular and left bundle-branch block
0.568 0.432 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.568 0.432 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.567 0.433 0.000
L88 Pyoderma gangrenosum
0.567 0.433 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.566 0.434 0.000
H10-H13 Disorders of conjunctiva
0.566 0.434 0.000
L87 Transepidermal elimination disorders
0.566 0.434 0.000
L86 Keratoderma in diseases classified elsewhere
0.566 0.434 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.565 0.435 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.565 0.435 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.564 0.435 0.000
W50-W64 Exposure to animate mechanical forces
0.564 0.435 0.000
R00 Abnormalities of heart beat
0.564 0.436 0.000
R46 Symptoms and signs involving appearance and behaviour
0.564 0.436 0.000
A80-A89 Viral infections of the central nervous system
0.564 0.436 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.563 0.436 0.000
L65 Other nonscarring hair loss
0.563 0.436 0.000
E14 Unspecified diabetes mellitus
0.563 0.437 0.000
L70 Acne
0.563 0.437 0.000
V10-V19 Pedal cyclist injured in transport accident
0.562 0.437 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.562 0.438 0.000
W20-W49 Exposure to inanimate mechanical forces
0.562 0.438 0.000
L68 Hypertrichosis
0.562 0.438 0.000
L63 Alopecia areata
0.561 0.438 0.000
L75 Apocrine sweat disorders
0.561 0.439 0.000
L74 Eccrine sweat disorders
0.561 0.439 0.000
L67 Hair colour and hair shaft abnormalities
0.561 0.439 0.000
L64 Androgenic alopecia
0.561 0.439 0.000
L62 Nail disorders in diseases classified elsewhere
0.561 0.439 0.000
B65-B83 Helminthiases
0.561 0.439 0.000
I73 Other peripheral vascular diseases
0.561 0.439 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.561 0.439 0.000
A15-A19 Tuberculosis
0.560 0.439 0.000
B99-B99 Other infectious diseases
0.560 0.440 0.000
F42 Obsessive-compulsive disorder
0.560 0.440 0.000
I38 Endocarditis, valve unspecified
0.560 0.440 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.560 0.440 0.000
Y00-Y09 Assault
0.559 0.441 0.000
A65-A69 Other spirochaetal diseases
0.559 0.441 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.559 0.441 0.000
M15 Polyarthrosis
0.559 0.441 0.000
F44 Dissociative [conversion] disorders
0.559 0.441 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.558 0.442 0.000
A20-A28 Certain zoonotic bacterial diseases
0.558 0.442 0.000
V01-V09 Pedestrian injured in transport accident
0.558 0.442 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.558 0.442 0.000
A75-A79 Rickettsioses
0.558 0.442 0.000
A70-A74 Other diseases caused by chlamydiae
0.558 0.442 0.000
M16 Coxarthrosis [arthrosis of hip]
0.558 0.442 0.000
E11.9 Without complications
0.558 0.442 0.000
X10-X19 Contact with heat and hot substances
0.557 0.442 0.000
F40 Phobic anxiety disorders
0.557 0.442 0.000
X20-X29 Contact with venomous animals and plants
0.557 0.442 0.000
I72 Other aneurysm
0.557 0.443 0.000
F48 Other neurotic disorders
0.557 0.443 0.000
W75-W84 Other accidental threats to breathing
0.557 0.443 0.000
F43 Reaction to severe stress, and adjustment disorders
0.556 0.443 0.000
H55-H59 Other disorders of eye and adnexa
0.556 0.444 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.556 0.444 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.556 0.444 0.000
X00-X09 Exposure to smoke, fire and flames
0.556 0.444 0.000
Y10-Y34 Event of undetermined intent
0.555 0.444 0.000
V90-V94 Water transport accidents
0.555 0.444 0.000
V98-V99 Other and unspecified transport accidents
0.555 0.444 0.000
V70-V79 Bus occupant injured in transport accident
0.555 0.445 0.000
V95-V97 Air and space transport accidents
0.555 0.445 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.555 0.445 0.000
X30-X39 Exposure to forces of nature
0.555 0.445 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.555 0.445 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.555 0.445 0.000
L94 Other localised connective tissue disorders
0.554 0.446 0.000
Y35-Y36 Legal intervention and operations of war
0.554 0.446 0.000
X85-X99 Assault
0.554 0.446 0.000
W65-W74 Accidental drowning and submersion
0.554 0.446 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.554 0.446 0.000
L91 Hypertrophic disorders of skin
0.554 0.446 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.553 0.446 0.000
R01 Cardiac murmurs and other cardiac sounds
0.553 0.447 0.000
E12 Malnutrition-related diabetes mellitus
0.552 0.447 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.552 0.448 0.000
F41.9 Anxiety disorder, unspecified
0.552 0.448 0.000
V20-V29 Motorcycle rider injured in transport accident
0.552 0.448 0.000
V40-V49 Car occupant injured in transport accident
0.552 0.448 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.551 0.449 0.000
L72.1 Trichilemmal cyst
0.551 0.449 0.000
M17 Gonarthrosis [arthrosis of knee]
0.551 0.449 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.550 0.450 0.000
I30 Acute pericarditis
0.550 0.450 0.000
V80-V89 Other land transport accidents
0.549 0.451 0.000
I49 Other cardiac arrhythmias
0.549 0.451 0.000
M25.7 Osteophyte
0.549 0.451 0.000
I28 Other diseases of pulmonary vessels
0.549 0.451 0.000
M51 Other intervertebral disk disorders
0.549 0.451 0.000
I78 Diseases of capillaries
0.548 0.452 0.000
B15-B19 Viral hepatitis
0.548 0.452 0.000
X50-X57 Overexertion, travel and privation
0.548 0.452 0.000
L90 Atrophic disorders of skin
0.547 0.452 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.547 0.452 0.000
I36 Nonrheumatic tricuspid valve disorders
0.546 0.453 0.000
I37 Pulmonary valve disorders
0.546 0.454 0.000
I31 Other diseases of pericardium
0.546 0.454 0.000
R43 Disturbances of smell and taste
0.546 0.454 0.000
L72.0 Epidermal cyst
0.546 0.454 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.545 0.454 0.000
I27 Other pulmonary heart diseases
0.545 0.455 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.545 0.455 0.000
B50-B64 Protozoal diseases
0.545 0.455 0.000
Z83.5 Family history of eye and ear disorders
0.545 0.455 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.544 0.455 0.000
I40 Acute myocarditis
0.544 0.456 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.544 0.456 0.000
I52 Other heart disorders in diseases classified elsewhere
0.543 0.457 0.000
I48 Atrial fibrillation and flutter
0.543 0.457 0.000
I41 Myocarditis in diseases classified elsewhere
0.543 0.457 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.543 0.457 0.000
I32 Pericarditis in diseases classified elsewhere
0.543 0.457 0.000
L73 Other follicular disorders
0.542 0.458 0.000
D10-D36 Benign neoplasms
0.542 0.458 0.000
E13 Other specified diabetes mellitus
0.542 0.458 0.000
O85-O92 Complications predominantly related to the puerperium
0.542 0.458 0.000
D80-D89 Certain disorders involving the immune mechanism
0.541 0.459 0.000
Z80 Family history of malignant neoplasm
0.540 0.459 0.000
M54 Dorsalgia
0.540 0.460 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.539 0.460 0.000
Z83.7 Family history of diseases of the digestive system
0.539 0.461 0.000
M25.5 Pain in joint
0.539 0.461 0.000
R63.4 Abnormal weight loss
0.539 0.461 0.000
L85 Other epidermal thickening
0.539 0.461 0.000
E66.0 Obesity due to excess calories
0.538 0.462 0.000
R47 Speech disturbances, not elsewhere classified
0.538 0.462 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.538 0.462 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.537 0.463 0.000
H40-H42 Glaucoma
0.537 0.463 0.000
F11 Mental and behavioural disorders due to use of opioids
0.537 0.463 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.536 0.463 0.000
H30-H36 Disorders of choroid and retina
0.536 0.463 0.000
E66.1 Drug-induced obesity
0.536 0.464 0.000
L29 Pruritus
0.536 0.464 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.535 0.465 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.535 0.465 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.534 0.466 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.534 0.466 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.534 0.466 0.000
M45 Ankylosing spondylitis
0.533 0.466 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.533 0.467 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.533 0.467 0.000
I34 Nonrheumatic mitral valve disorders
0.533 0.467 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.533 0.467 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.532 0.467 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.532 0.468 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.532 0.468 0.000
I22.8 Subsequent myocardial infarction of other sites
0.532 0.468 0.000
C50-C50 Malignant neoplasm of breast
0.531 0.469 0.000
M19.9 Arthrosis, unspecified
0.531 0.469 0.000
E66.8 Other obesity
0.530 0.469 0.000
I70 Atherosclerosis
0.530 0.470 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.529 0.470 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.529 0.470 0.000
D00-D09 In situ neoplasms
0.529 0.471 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.529 0.471 0.000
L30 Other dermatitis
0.528 0.471 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.528 0.472 0.000
L27 Dermatitis due to substances taken internally
0.528 0.472 0.000
R56.8 Other and unspecified convulsions
0.527 0.473 0.000
I95 Hypotension
0.526 0.474 0.000
R80 Isolated proteinuria
0.526 0.474 0.000
X60-X84 Intentional self-harm
0.526 0.474 0.000
I99 Other and unspecified disorders of circulatory system
0.526 0.474 0.000
L81 Other disorders of pigmentation
0.525 0.475 0.000
R82 Other abnormal findings in urine
0.525 0.475 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.524 0.476 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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