TreeWAS – Variant ID: rs77130284

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	0.440	0.560	0.000
E03.5 Myxoedema coma	0.315	0.685	0.000
E03.4 Atrophy of thyroid (acquired)	0.315	0.685	0.000
E03.3 Postinfectious hypothyroidism	0.315	0.685	0.000
E03.1 Congenital hypothyroidism without goitre	0.315	0.685	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.315	0.685	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.287	0.712	0.000
E03.8 Other specified hypothyroidism	0.267	0.732	0.000
E00-E07 Disorders of thyroid gland	0.203	0.797	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.160	0.840	0.000
E06 Thyroiditis	0.157	0.843	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.145	0.855	0.000
E00 Congenital iodine-deficiency syndrome	0.145	0.855	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.145	0.855	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.141	0.859	0.000
E06.3 Autoimmune thyroiditis	0.137	0.863	0.000
E05.9 Thyrotoxicosis, unspecified	0.119	0.881	0.000
E07 Other disorders of thyroid	0.116	0.884	0.000
E05.5 Thyroid crisis or storm	0.115	0.885	0.000
E05.4 Thyrotoxicosis factitia	0.115	0.885	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.115	0.885	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.115	0.885	0.000
E06.5 Other chronic thyroiditis	0.112	0.887	0.000
E06.4 Drug-induced thyroiditis	0.112	0.887	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.112	0.887	0.000
E06.1 Subacute thyroiditis	0.112	0.887	0.000
E06.0 Acute thyroiditis	0.112	0.887	0.000
E05.8 Other thyrotoxicosis	0.108	0.892	0.000
E04 Other non-toxic goitre	0.106	0.894	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.104	0.895	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.104	0.895	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.104	0.895	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.104	0.895	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.104	0.895	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.104	0.895	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.104	0.895	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.104	0.895	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.092	0.908	0.000
E07.8 Other specified disorders of thyroid	0.090	0.910	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.089	0.911	0.000
E20-E35 Disorders of other endocrine glands	0.086	0.914	0.000
E04.1 Non-toxic single thyroid nodule	0.084	0.916	0.000
E06.9 Thyroiditis, unspecified	0.083	0.916	0.000
E07.1 Dyshormogenetic goitre	0.083	0.917	0.000
E07.0 Hypersecretion of calcitonin	0.083	0.917	0.000
E34 Other endocrine disorders	0.082	0.918	0.000
E04.0 Non-toxic diffuse goitre	0.079	0.921	0.000
E27 Other disorders of adrenal gland	0.079	0.921	0.000
D50.9 Iron deficiency anaemia, unspecified	0.077	0.923	0.000
E04.8 Other specified non-toxic goitre	0.076	0.923	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.073	0.927	0.000
E34.0 Carcinoid syndrome	0.073	0.927	0.000
E27.2 Addisonian crisis	0.072	0.928	0.000
E50-E64 Other nutritional deficiencies	0.072	0.928	0.000
E27.1 Primary adrenocortical insufficiency	0.070	0.930	0.000
E31 Polyglandular dysfunction	0.070	0.930	0.000
E40-E46 Malnutrition	0.070	0.930	0.000
E34.9 Endocrine disorder, unspecified	0.069	0.931	0.000
E20 Hypoparathyroidism	0.068	0.931	0.000
E61 Deficiency of other nutrient elements	0.068	0.932	0.000
E22 Hyperfunction of pituitary gland	0.068	0.932	0.000
E34.8 Other specified endocrine disorders	0.066	0.934	0.000
E61.1 Iron deficiency	0.065	0.935	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.062	0.938	0.000
E32 Diseases of thymus	0.062	0.938	0.000
E30 Disorders of puberty, not elsewhere classified	0.062	0.938	0.000
E25 Adrenogenital disorders	0.062	0.938	0.000
E65-E68 Obesity and other hyperalimentation	0.061	0.939	0.000
E28 Ovarian dysfunction	0.061	0.939	0.000
E26 Hyperaldosteronism	0.061	0.939	0.000
E16 Other disorders of pancreatic internal secretion	0.060	0.940	0.000
E04.2 Non-toxic multinodular goitre	0.060	0.940	0.000
D50 Iron deficiency anaemia	0.060	0.940	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.059	0.941	0.000
E34.5 Androgen resistance syndrome	0.059	0.941	0.000
E34.4 Constitutional tall stature	0.059	0.941	0.000
E34.3 Short stature, not elsewhere classified	0.059	0.941	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.059	0.941	0.000
E34.1 Other hypersecretion of intestinal hormones	0.059	0.941	0.000
E31.0 Autoimmune polyglandular failure	0.058	0.942	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.057	0.942	0.000
D50-D53 Nutritional anaemias	0.057	0.943	0.000
E27.5 Adrenomedullary hyperfunction	0.056	0.943	0.000
E27.0 Other adrenocortical overactivity	0.056	0.943	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.056	0.944	0.000
E20.9 Hypoparathyroidism, unspecified	0.056	0.944	0.000
E65 Localised adiposity	0.054	0.946	0.000
E29 Testicular dysfunction	0.054	0.946	0.000
E46 Unspecified protein-energy malnutrition	0.054	0.946	0.000
E24 Cushing's syndrome	0.053	0.947	0.000
E15 Nondiabetic hypoglycaemic coma	0.053	0.947	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.052	0.948	0.000
E63 Other nutritional deficiencies	0.052	0.948	0.000
E56 Other vitamin deficiencies	0.052	0.948	0.000
E51 Thiamine deficiency	0.052	0.948	0.000
E50 Vitamin A deficiency	0.052	0.948	0.000
E60 Dietary zinc deficiency	0.052	0.948	0.000
E59 Dietary selenium deficiency	0.052	0.948	0.000
E58 Dietary calcium deficiency	0.052	0.948	0.000
E54 Ascorbic acid deficiency	0.052	0.948	0.000
E52 Niacin deficiency [pellagra]	0.052	0.948	0.000
D52 Folate deficiency anaemia	0.052	0.948	0.000
E16.2 Hypoglycaemia, unspecified	0.051	0.949	0.000
E22.0 Acromegaly and pituitary gigantism	0.050	0.949	0.000
E61.2 Magnesium deficiency	0.050	0.949	0.000
E31.9 Polyglandular dysfunction, unspecified	0.050	0.950	0.000
E31.8 Other polyglandular dysfunction	0.050	0.950	0.000
E31.1 Polyglandular hyperfunction	0.050	0.950	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.050	0.950	0.000
E45 Retarded development following protein-energy malnutrition	0.050	0.950	0.000
E43 Unspecified severe protein-energy malnutrition	0.050	0.950	0.000
E42 Marasmic kwashiorkor	0.050	0.950	0.000
E41 Nutritional marasmus	0.050	0.950	0.000
E40 Kwashiorkor	0.050	0.950	0.000
D51 Vitamin B12 deficiency anaemia	0.049	0.950	0.000
E20.8 Other hypoparathyroidism	0.049	0.951	0.000
E20.1 Pseudohypoparathyroidism	0.049	0.951	0.000
E20.0 Idiopathic hypoparathyroidism	0.049	0.951	0.000
E61.9 Deficiency of nutrient element, unspecified	0.049	0.951	0.000
E61.8 Deficiency of other specified nutrient elements	0.049	0.951	0.000
E61.7 Deficiency of multiple nutrient elements	0.049	0.951	0.000
E61.6 Vanadium deficiency	0.049	0.951	0.000
E61.5 Molybdenum deficiency	0.049	0.951	0.000
E61.4 Chromium deficiency	0.049	0.951	0.000
E61.3 Manganese deficiency	0.049	0.951	0.000
E61.0 Copper deficiency	0.049	0.951	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.049	0.951	0.000
E22.8 Other hyperfunction of pituitary gland	0.049	0.951	0.000
E28.2 Polycystic ovarian syndrome	0.048	0.951	0.000
D86 Sarcoidosis	0.048	0.952	0.000
D80-D89 Certain disorders involving the immune mechanism	0.048	0.952	0.000
E27.9 Disorder of adrenal gland, unspecified	0.048	0.952	0.000
D52.9 Folate deficiency anaemia, unspecified	0.048	0.952	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.047	0.953	0.000
E10-E14 Diabetes mellitus	0.046	0.954	0.000
M06 Other rheumatoid arthritis	0.046	0.954	0.000
M06.9 Rheumatoid arthritis, unspecified	0.046	0.954	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.046	0.954	0.000
E25.9 Adrenogenital disorder, unspecified	0.044	0.955	0.000
E25.8 Other adrenogenital disorders	0.044	0.955	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.044	0.955	0.000
E30.9 Disorder of puberty, unspecified	0.044	0.955	0.000
E30.8 Other disorders of puberty	0.044	0.955	0.000
E30.1 Precocious puberty	0.044	0.955	0.000
E30.0 Delayed puberty	0.044	0.955	0.000
E32.9 Disease of thymus, unspecified	0.044	0.955	0.000
E32.8 Other diseases of thymus	0.044	0.955	0.000
E32.1 Abscess of thymus	0.044	0.955	0.000
E32.0 Persistent hyperplasia of thymus	0.044	0.955	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.044	0.955	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.044	0.955	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.044	0.955	0.000
E67 Other hyperalimentation	0.044	0.956	0.000
E68 Sequelae of hyperalimentation	0.044	0.956	0.000
E28.9 Ovarian dysfunction, unspecified	0.044	0.956	0.000
E28.8 Other ovarian dysfunction	0.044	0.956	0.000
E28.1 Androgen excess	0.044	0.956	0.000
E28.0 Oestrogen excess	0.044	0.956	0.000
D86.9 Sarcoidosis, unspecified	0.044	0.956	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.044	0.956	0.000
E26.9 Hyperaldosteronism, unspecified	0.044	0.956	0.000
E26.8 Other hyperaldosteronism	0.044	0.956	0.000
E26.1 Secondary hyperaldosteronism	0.044	0.956	0.000
E22.1 Hyperprolactinaemia	0.043	0.956	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.043	0.957	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.043	0.957	0.000
E16.4 Abnormal secretion of gastrin	0.043	0.957	0.000
E16.3 Increased secretion of glucagon	0.043	0.957	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.043	0.957	0.000
M06.4 Inflammatory polyarthropathy	0.043	0.957	0.000
D50.1 Sideropenic dysphagia	0.043	0.957	0.000
E26.0 Primary hyperaldosteronism	0.042	0.957	0.000
E16.1 Other hypoglycaemia	0.042	0.958	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.042	0.958	0.000
D53 Other nutritional anaemias	0.041	0.958	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.041	0.959	0.000
D86.0 Sarcoidosis of lung	0.041	0.959	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.041	0.959	0.000
D80 Immunodeficiency with predominantly antibody defects	0.040	0.960	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.040	0.960	0.000
E04.9 Non-toxic goitre, unspecified	0.039	0.961	0.000
E29.9 Testicular dysfunction, unspecified	0.039	0.961	0.000
E29.8 Other testicular dysfunction	0.039	0.961	0.000
E29.0 Testicular hyperfunction	0.039	0.961	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.039	0.961	0.000
D86.3 Sarcoidosis of skin	0.039	0.961	0.000
E27.8 Other specified disorders of adrenal gland	0.038	0.961	0.000
E53 Deficiency of other B group vitamins	0.038	0.961	0.000
E24.8 Other Cushing's syndrome	0.038	0.961	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.038	0.961	0.000
E24.3 Ectopic ACTH syndrome	0.038	0.961	0.000
E24.2 Drug-induced Cushing's syndrome	0.038	0.961	0.000
E24.1 Nelson's syndrome	0.038	0.961	0.000
E24.0 Pituitary-dependent Cushing's disease	0.038	0.961	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.038	0.962	0.000
D55-D59 Haemolytic anaemias	0.038	0.962	0.000
M05-M14 Inflammatory polyarthropathies	0.038	0.962	0.000
M06.0 Seronegative rheumatoid arthritis	0.038	0.962	0.000
E07.9 Disorder of thyroid, unspecified	0.037	0.962	0.000
E28.3 Primary ovarian failure	0.037	0.962	0.000
E50.9 Vitamin A deficiency, unspecified	0.037	0.962	0.000
E50.8 Other manifestations of vitamin A deficiency	0.037	0.962	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.037	0.962	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.037	0.962	0.000
E50.5 Vitamin A deficiency with night blindness	0.037	0.962	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.037	0.962	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.037	0.962	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.037	0.962	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.037	0.962	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.037	0.962	0.000
E51.9 Thiamine deficiency, unspecified	0.037	0.962	0.000
E51.8 Other manifestations of thiamine deficiency	0.037	0.962	0.000
E51.2 Wernicke's encephalopathy	0.037	0.962	0.000
E51.1 Beriberi	0.037	0.962	0.000
E56.9 Vitamin deficiency, unspecified	0.037	0.962	0.000
E56.8 Deficiency of other vitamins	0.037	0.962	0.000
E56.1 Deficiency of vitamin K	0.037	0.962	0.000
E56.0 Deficiency of vitamin E	0.037	0.962	0.000
E63.9 Nutritional deficiency, unspecified	0.037	0.962	0.000
E63.8 Other specified nutritional deficiencies	0.037	0.962	0.000
E63.1 Imbalance of constituents of food intake	0.037	0.962	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.037	0.962	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.037	0.962	0.000
E64.8 Sequelae of other nutritional deficiencies	0.037	0.962	0.000
E64.3 Sequelae of rickets	0.037	0.962	0.000
E64.2 Sequelae of vitamin C deficiency	0.037	0.962	0.000
E64.1 Sequelae of vitamin A deficiency	0.037	0.962	0.000
E64.0 Sequelae of protein-energy malnutrition	0.037	0.962	0.000
D86.1 Sarcoidosis of lymph nodes	0.037	0.963	0.000
E14 Unspecified diabetes mellitus	0.037	0.963	0.000
D52.8 Other folate deficiency anaemias	0.037	0.963	0.000
D52.1 Drug-induced folate deficiency anaemia	0.037	0.963	0.000
D52.0 Dietary folate deficiency anaemia	0.037	0.963	0.000
D83 Common variable immunodeficiency	0.037	0.963	0.000
M06.8 Other specified rheumatoid arthritis	0.036	0.963	0.000
M11 Other crystal arthropathies	0.036	0.963	0.000
E23 Hypofunction and other disorders of pituitary gland	0.036	0.964	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.036	0.964	0.000
E44.1 Mild protein-energy malnutrition	0.036	0.964	0.000
E44.0 Moderate protein-energy malnutrition	0.036	0.964	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.036	0.964	0.000
D86.8 Sarcoidosis of other and combined sites	0.036	0.964	0.000
D22.5 Melanocytic naevi of trunk	0.000	0.964	0.036
D51.8 Other vitamin B12 deficiency anaemias	0.036	0.964	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.036	0.964	0.000
D51.2 Transcobalamin II deficiency	0.036	0.964	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.036	0.964	0.000
E10 Insulin-dependent diabetes mellitus	0.035	0.965	0.000
M11.2 Other chondrocalcinosis	0.035	0.965	0.000
D82 Immunodeficiency associated with other major defects	0.035	0.965	0.000
D81 Combined immunodeficiencies	0.035	0.965	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.034	0.966	0.000
E55 Vitamin D deficiency	0.033	0.966	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.034	0.966	0.000
D84 Other immunodeficiencies	0.034	0.966	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.034	0.966	0.000
M07 Psoriatic and enteropathic arthropathies	0.034	0.966	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.034	0.966	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.034	0.966	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.034	0.966	0.000
E10.4 With neurological complications	0.034	0.966	0.000
E12 Malnutrition-related diabetes mellitus	0.033	0.967	0.000
M06.2 Rheumatoid bursitis	0.033	0.967	0.000
M06.1 Adult-onset Still's disease	0.033	0.967	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.033	0.967	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.033	0.967	0.000
D58 Other hereditary haemolytic anaemias	0.032	0.968	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.032	0.968	0.000
E67.8 Other specified hyperalimentation	0.032	0.968	0.000
E67.3 Hypervitaminosis D	0.032	0.968	0.000
E67.2 Megavitamin-B6 syndrome	0.032	0.968	0.000
E67.1 Hypercarotenaemia	0.032	0.968	0.000
E67.0 Hypervitaminosis A	0.032	0.968	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.032	0.968	0.000
E14.4 With neurological complications	0.032	0.968	0.000
M06.3 Rheumatoid nodule	0.032	0.968	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.031	0.969	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.031	0.969	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.031	0.969	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.031	0.969	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.031	0.969	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.031	0.969	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.031	0.969	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.031	0.969	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.031	0.969	0.000
M07.3 Other psoriatic arthropathies	0.031	0.969	0.000
E29.1 Testicular hypofunction	0.031	0.969	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.031	0.969	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.031	0.969	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.031	0.969	0.000
D53.9 Nutritional anaemia, unspecified	0.030	0.970	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.030	0.970	0.000
E21.4 Other specified disorders of parathyroid gland	0.030	0.970	0.000
E21.2 Other hyperparathyroidism	0.030	0.970	0.000
D53.8 Other specified nutritional anaemias	0.030	0.970	0.000
D53.2 Scorbutic anaemia	0.030	0.970	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.030	0.970	0.000
D53.0 Protein deficiency anaemia	0.030	0.970	0.000
E14.2 Withrenal complications	0.030	0.970	0.000
E24.9 Cushing's syndrome, unspecified	0.030	0.970	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.030	0.970	0.000
D89.3 Immune reconstitution syndrome	0.030	0.970	0.000
D89.1 Cryoglobulinaemia	0.030	0.970	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.030	0.970	0.000
D59 Acquired haemolytic anaemia	0.029	0.970	0.000
D56 Thalassaemia	0.029	0.971	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.029	0.971	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.029	0.971	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.029	0.971	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.029	0.971	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.029	0.971	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.029	0.971	0.000
M05 Seropositive rheumatoid arthritis	0.029	0.971	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.029	0.971	0.000
D83.9 Common variable immunodeficiency, unspecified	0.029	0.971	0.000
M10 Gout	0.029	0.971	0.000
M11.9 Crystal arthropathy, unspecified	0.029	0.971	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.029	0.971	0.000
E21.0 Primary hyperparathyroidism	0.028	0.972	0.000
E13 Other specified diabetes mellitus	0.028	0.972	0.000
E53.1 Pyridoxine deficiency	0.028	0.972	0.000
E53.0 Riboflavin deficiency	0.028	0.972	0.000
E10.8 With unspecified complications	0.028	0.972	0.000
M12 Other specific arthropathies	0.028	0.972	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.028	0.972	0.000
M08 Juvenile arthritis	0.028	0.972	0.000
D57 Sickle-cell disorders	0.028	0.972	0.000
D55 Anaemia due to enzyme disorders	0.028	0.972	0.000
E14.1 With ketoacidosis	0.027	0.972	0.000
E14.8 With unspecified complications	0.027	0.973	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.027	0.973	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.027	0.973	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.027	0.973	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.027	0.973	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.027	0.973	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.027	0.973	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.027	0.973	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.027	0.973	0.000
M14 Arthropathies in other diseases classified elsewhere	0.027	0.973	0.000
E23.7 Disorder of pituitary gland, unspecified	0.027	0.973	0.000
E14.7 With multiple complications	0.027	0.973	0.000
E14.6 With other specified complications	0.027	0.973	0.000
E14.5 With peripheral circulatory complications	0.027	0.973	0.000
E14.0 With coma	0.027	0.973	0.000
E53.9 Vitamin B deficiency, unspecified	0.027	0.973	0.000
D83.8 Other common variable immunodeficiencies	0.027	0.973	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.027	0.973	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.027	0.973	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.027	0.973	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.027	0.973	0.000
E10.0 With coma	0.027	0.973	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.026	0.973	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.026	0.973	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.026	0.973	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.026	0.973	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.026	0.973	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.026	0.973	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.026	0.973	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.026	0.973	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.026	0.973	0.000
M11.8 Other specified crystal arthropathies	0.026	0.974	0.000
M11.1 Familial chondrocalcinosis	0.026	0.974	0.000
M11.0 Hydroxyapatite deposition disease	0.026	0.974	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.026	0.974	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.026	0.974	0.000
E23.1 Drug-induced hypopituitarism	0.026	0.974	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.026	0.974	0.000
D58.0 Hereditary spherocytosis	0.026	0.974	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.026	0.974	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.025	0.974	0.000
E10.6 With other specified complications	0.025	0.974	0.000
E10.7 With multiple complications	0.025	0.975	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.025	0.975	0.000
M11.28 Other chondrocalcinosis (Other)	0.025	0.975	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.025	0.975	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.025	0.975	0.000
M11.24 Other chondrocalcinosis (Hand)	0.025	0.975	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.025	0.975	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.025	0.975	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.025	0.975	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.025	0.975	0.000
D81.9 Combined immunodeficiency, unspecified	0.025	0.975	0.000
D81.8 Other combined immunodeficiencies	0.025	0.975	0.000
D81.7 Major histocompatibility complex class II deficiency	0.025	0.975	0.000
D81.6 Major histocompatibility complex class I deficiency	0.025	0.975	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.025	0.975	0.000
D81.4 Nezelof's syndrome	0.025	0.975	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.025	0.975	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.025	0.975	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.025	0.975	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.025	0.975	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.025	0.975	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.025	0.975	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.025	0.975	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.025	0.975	0.000
D82.2 Immunodeficiency with short-limbed stature	0.025	0.975	0.000
D82.1 Di George's syndrome	0.025	0.975	0.000
D82.0 Wiskott-Aldrich syndrome	0.025	0.975	0.000
E55.0 Rickets, active	0.023	0.975	0.001
D84.8 Other specified immunodeficiencies	0.025	0.975	0.000
D84.1 Defects in the complement system	0.025	0.975	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.025	0.975	0.000
M07.6 Other enteropathic arthropathies	0.025	0.975	0.000
M07.5 Arthropathy in ulcerative colitis	0.025	0.975	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.025	0.975	0.000
M07.2 Psoriatic spondylitis	0.025	0.975	0.000
M07.1 Arthritis mutilans	0.025	0.975	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.025	0.975	0.000
E14.3 With ophthalmic complications	0.024	0.975	0.000
M06.34 Rheumatoid nodule (Hand)	0.024	0.976	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.024	0.976	0.000
D84.9 Immunodeficiency, unspecified	0.024	0.976	0.000
E12.9 Without complications	0.024	0.976	0.000
E12.8 With unspecified complications	0.024	0.976	0.000
E12.7 With multiple complications	0.024	0.976	0.000
E12.6 With other specified complications	0.024	0.976	0.000
E12.5 With peripheral circulatory complications	0.024	0.976	0.000
E12.4 With neurological complications	0.024	0.976	0.000
E12.3 With ophthalmic complications	0.024	0.976	0.000
E12.2 With renal complications	0.024	0.976	0.000
E12.1 With ketoacidosis	0.024	0.976	0.000
E12.0 With coma	0.024	0.976	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.024	0.976	0.000
M06.18 Adult-onset Still's disease (Other)	0.024	0.976	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.024	0.976	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.024	0.976	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.024	0.976	0.000
M06.14 Adult-onset Still's disease (Hand)	0.024	0.976	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.024	0.976	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.024	0.976	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.024	0.976	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.024	0.976	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.024	0.976	0.000
M06.28 Rheumatoid bursitis (Other)	0.024	0.976	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.024	0.976	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.024	0.976	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.024	0.976	0.000
M06.24 Rheumatoid bursitis (Hand)	0.024	0.976	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.024	0.976	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.024	0.976	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.024	0.976	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.024	0.976	0.000
E14.9 Without complications	0.023	0.977	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.023	0.977	0.000
D58.2 Other haemoglobinopathies	0.023	0.977	0.000
D58.1 Hereditary elliptocytosis	0.023	0.977	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.023	0.977	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.023	0.977	0.000
M06.38 Rheumatoid nodule (Other)	0.023	0.977	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.023	0.977	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.023	0.977	0.000
M06.33 Rheumatoid nodule (Forearm)	0.023	0.977	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.023	0.977	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.023	0.977	0.000
D56.3 Thalassaemia trait	0.023	0.977	0.000
E23.6 Other disorders of pituitary gland	0.022	0.977	0.000
E10.2 With renal complications	0.023	0.977	0.000
M07.38 Other psoriatic arthropathies (Other)	0.022	0.977	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.022	0.977	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.022	0.977	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.022	0.977	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.022	0.977	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.022	0.977	0.000
D59.1 Other autoimmune haemolytic anaemias	0.022	0.977	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.022	0.977	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.022	0.978	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.022	0.978	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.022	0.978	0.000
E10.9 Without complications	0.022	0.978	0.000
M10.0 Idiopathic gout	0.021	0.978	0.000
D59.8 Other acquired haemolytic anaemias	0.021	0.979	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.021	0.979	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.021	0.979	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.021	0.979	0.000
D59.3 Haemolytic-uraemic syndrome	0.021	0.979	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.021	0.979	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.021	0.979	0.000
M10.9 Gout, unspecified	0.021	0.979	0.000
D56.9 Thalassaemia, unspecified	0.021	0.979	0.000
D56.8 Other thalassaemias	0.021	0.979	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.021	0.979	0.000
D56.2 Delta-beta thalassaemia	0.021	0.979	0.000
D56.1 Beta thalassaemia	0.021	0.979	0.000
D56.0 Alpha thalassaemia	0.021	0.979	0.000
E10.3 With ophthalmic complications	0.021	0.979	0.000
E23.2 Diabetes insipidus	0.021	0.979	0.000
M05.8 Other seropositive rheumatoid arthritis	0.021	0.979	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.021	0.979	0.000
M05.2 Rheumatoid vasculitis	0.021	0.979	0.000
M05.1 Rheumatoid lung disease	0.021	0.979	0.000
M05.0 Felty's syndrome	0.021	0.979	0.000
M10.4 Other secondary gout	0.021	0.979	0.000
M10.3 Gout due to impairment of renal function	0.021	0.979	0.000
M10.2 Drug-induced gout	0.021	0.979	0.000
M10.1 Lead-induced gout	0.021	0.979	0.000
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.021	0.979	0.000
M11.98 Crystal arthropathy, unspecified (Other)	0.021	0.979	0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.021	0.979	0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.021	0.979	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations