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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79694611
log Bayes Factor = 14.1335
Chromosome 14   position 94,593,576  (GRCh37) Explore rs79694611 on Ensembl!
Variant rs79694611 is part of Cluster X0146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.993 0.007 0.000
N17-N19 Renal failure
0.990 0.010 0.000
I47 Paroxysmal tachycardia
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.984 0.016 0.000
Chapter VII Diseases of the eye and adnexa
0.983 0.017 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.979 0.021 0.000
I47.2 Ventricular tachycardia
0.972 0.028 0.000
M20-M25 Other joint disorders
0.971 0.029 0.000
C15-C26 Malignant neoplasms of digestive organs
0.970 0.030 0.000
N18 Chronic renal failure
0.966 0.034 0.000
M25 Other joint disorders, not elsewhere classified
0.964 0.036 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.960 0.040 0.000
I51 Complications and ill-defined descriptions of heart disease
0.955 0.045 0.000
Chapter I Certain infectious and parasitic diseases
0.949 0.051 0.000
S00-S09 Injuries to the head
0.946 0.054 0.000
I26 Pulmonary embolism
0.943 0.057 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.936 0.064 0.000
M45-M49 Spondylopathies
0.936 0.064 0.000
H40-H42 Glaucoma
0.932 0.068 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.932 0.068 0.000
N17 Acute renal failure
0.928 0.072 0.000
C18 Malignant neoplasm of colon
0.927 0.073 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.923 0.077 0.000
M25.5 Pain in joint
0.920 0.080 0.000
C50-C50 Malignant neoplasm of breast
0.920 0.080 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.918 0.082 0.000
C79 Secondary malignant neoplasm of other sites
0.916 0.084 0.000
M70-M79 Other soft tissue disorders
0.915 0.085 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.907 0.093 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.905 0.095 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.905 0.095 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.904 0.096 0.000
I35 Nonrheumatic aortic valve disorders
0.898 0.102 0.000
N18.3 Chronic kidney disease, stage 3
0.897 0.103 0.000
H40 Glaucoma
0.896 0.104 0.000
E10-E14 Diabetes mellitus
0.894 0.106 0.000
S09 Other and unspecified injuries of head
0.894 0.106 0.000
S80-S89 Injuries to the knee and lower leg
0.890 0.110 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.889 0.111 0.000
N17.9 Acute renal failure, unspecified
0.884 0.116 0.000
I51.8 Other ill-defined heart diseases
0.883 0.117 0.000
Chapter XX External causes of morbidity and mortality
0.881 0.119 0.000
C64-C68 Malignant neoplasms of urinary tract
0.881 0.119 0.000
M25.56 Pain in joint (Lower leg)
0.877 0.123 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.877 0.123 0.000
I49 Other cardiac arrhythmias
0.875 0.125 0.000
N20-N23 Urolithiasis
0.872 0.128 0.000
M05-M14 Inflammatory polyarthropathies
0.870 0.130 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.869 0.131 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.868 0.132 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.865 0.134 0.000
M25.4 Effusion of joint
0.865 0.135 0.000
I51.7 Cardiomegaly
0.864 0.136 0.000
C50 Malignant neoplasm of breast
0.863 0.137 0.000
I60-I69 Cerebrovascular diseases
0.860 0.140 0.000
E10 Insulin-dependent diabetes mellitus
0.860 0.140 0.000
M47 Spondylosis
0.859 0.141 0.000
S09.9 Unspecified injury of head
0.857 0.143 0.000
I05-I09 Chronic rheumatic heart diseases
0.857 0.143 0.000
M80-M85 Disorders of bone density and structure
0.854 0.146 0.000
R10 Abdominal and pelvic pain
0.854 0.146 0.000
I47.1 Supraventricular tachycardia
0.849 0.151 0.000
C18.7 Sigmoid colon
0.848 0.152 0.000
I45 Other conduction disorders
0.847 0.153 0.000
I71 Aortic aneurysm and dissection
0.846 0.154 0.000
N19 Unspecified renal failure
0.845 0.155 0.000
R10.4 Other and unspecified abdominal pain
0.844 0.156 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.843 0.157 0.000
E70-E90 Metabolic disorders
0.841 0.159 0.000
B35-B49 Mycoses
0.840 0.160 0.000
I42 Cardiomyopathy
0.837 0.162 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.837 0.163 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.835 0.165 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.835 0.165 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.833 0.167 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.831 0.169 0.000
E20-E35 Disorders of other endocrine glands
0.828 0.172 0.000
N99-N99 Other disorders of the genitourinary system
0.827 0.173 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.826 0.174 0.000
Chapter XXII Codes for special purposes
0.826 0.174 0.000
M86-M90 Other osteopathies
0.825 0.175 0.000
R11 Nausea and vomiting
0.824 0.176 0.000
S82 Fracture of lower leg, including ankle
0.822 0.178 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.822 0.178 0.000
N18.5 Chronic kidney disease, stage 5
0.820 0.180 0.000
M13 Other arthritis
0.815 0.185 0.000
M47.8 Other spondylosis
0.815 0.185 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.812 0.188 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.812 0.188 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.811 0.189 0.000
A00-A09 Intestinal infectious diseases
0.810 0.190 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.808 0.192 0.000
Chapter XXI Factors influencing health status and contact with health services
0.806 0.194 0.000
N00-N08 Glomerular diseases
0.806 0.194 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.805 0.195 0.000
E10.3 With ophthalmic complications
0.805 0.195 0.000
C80 Malignant neoplasm without specification of site
0.804 0.196 0.000
N18.0 End-stage renal disease
0.804 0.196 0.000
L60-L75 Disorders of skin appendages
0.801 0.199 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.800 0.200 0.000
H00 Hordeolum and chalazion
0.800 0.200 0.000
Q60-Q64 Congenital malformations of the urinary system
0.798 0.202 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.796 0.204 0.000
C50.8 Overlapping lesion of breast
0.795 0.205 0.000
I77 Other disorders of arteries and arterioles
0.793 0.207 0.000
R26 Abnormalities of gait and mobility
0.793 0.207 0.000
M25.46 Effusion of joint (Lower leg)
0.792 0.208 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.792 0.208 0.000
Chapter V Mental and behavioural disorders
0.790 0.210 0.000
S90-S99 Injuries to the ankle and foot
0.789 0.211 0.000
H30-H36 Disorders of choroid and retina
0.789 0.211 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.788 0.212 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.788 0.212 0.000
E86 Volume depletion
0.787 0.213 0.000
I49.3 Ventricular premature depolarisation
0.787 0.213 0.000
E40-E46 Malnutrition
0.787 0.213 0.000
M46 Other inflammatory spondylopathies
0.787 0.213 0.000
I33 Acute and subacute endocarditis
0.786 0.214 0.000
H04 Disorders of lachrymal system
0.783 0.217 0.000
M25.0 Haemarthrosis
0.782 0.218 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.781 0.219 0.000
Chapter VIII Diseases of the ear and mastoid process
0.781 0.219 0.000
M24 Other specific joint derangements
0.780 0.220 0.000
E65-E68 Obesity and other hyperalimentation
0.779 0.221 0.000
I63 Cerebral infarction
0.778 0.222 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.777 0.223 0.000
M79.8 Other specified soft tissue disorders
0.776 0.224 0.000
M13.9 Arthritis, unspecified
0.775 0.225 0.000
H40.1 Primary open-angle glaucoma
0.774 0.226 0.000
N30-N39 Other diseases of urinary system
0.771 0.229 0.000
H40.9 Glaucoma, unspecified
0.770 0.230 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.768 0.232 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.768 0.232 0.000
S02 Fracture of skull and facial bones
0.768 0.232 0.000
C50.2 Upper-inner quadrant of breast
0.767 0.233 0.000
M25.8 Other specified joint disorders
0.763 0.237 0.000
Q80-Q89 Other congenital malformations
0.762 0.238 0.000
M60-M63 Disorders of muscles
0.762 0.238 0.000
R10.1 Pain localised to upper abdomen
0.761 0.239 0.000
N18.4 Chronic kidney disease, stage 4
0.761 0.239 0.000
C67 Malignant neoplasm of bladder
0.760 0.240 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.759 0.241 0.000
E10.2 With renal complications
0.758 0.242 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.757 0.243 0.000
M25.54 Pain in joint (Hand)
0.756 0.244 0.000
H10-H13 Disorders of conjunctiva
0.754 0.246 0.000
C18.9 Colon, unspecified
0.754 0.246 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.754 0.246 0.000
M79.6 Pain in limb
0.753 0.247 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.753 0.247 0.000
T66-T78 Other and unspecified effects of external causes
0.753 0.247 0.000
I08 Multiple valve diseases
0.753 0.247 0.000
H40.0 Glaucoma suspect
0.751 0.249 0.000
H43-H45 Disorders of vitreous body and globe
0.750 0.250 0.000
M35 Other systemic involvement of connective tissue
0.749 0.251 0.000
R47-R49 Symptoms and signs involving speech and voice
0.747 0.253 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.747 0.253 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.746 0.254 0.000
M22 Disorders of patella
0.746 0.254 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.746 0.254 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.745 0.255 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.744 0.256 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.743 0.257 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.742 0.258 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.742 0.258 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.741 0.259 0.000
H55-H59 Other disorders of eye and adnexa
0.740 0.260 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.738 0.262 0.000
S82.8 Fractures of other parts of lower leg
0.737 0.263 0.000
S40-S49 Injuries to the shoulder and upper arm
0.736 0.264 0.000
C50.0 Nipple and areola
0.736 0.264 0.000
H00.1 Chalazion
0.736 0.264 0.000
I49.4 Other and unspecified premature depolarisation
0.734 0.266 0.000
T42.4 Benzodiazepines
0.733 0.267 0.000
I42.0 Dilated cardiomyopathy
0.730 0.270 0.000
D60-D64 Aplastic and other anaemias
0.729 0.271 0.000
M72 Fibroblastic disorders
0.729 0.271 0.000
M21 Other acquired deformities of limbs
0.729 0.271 0.000
M40-M43 Deforming dorsopathies
0.728 0.272 0.000
I80 Phlebitis and thrombophlebitis
0.728 0.272 0.000
N20 Calculus of kidney and ureter
0.728 0.272 0.000
E50-E64 Other nutritional deficiencies
0.728 0.272 0.000
L90 Atrophic disorders of skin
0.728 0.272 0.000
I61 Intracerebral haemorrhage
0.727 0.273 0.000
X60-X84 Intentional self-harm
0.727 0.273 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.726 0.274 0.000
M25.7 Osteophyte
0.726 0.274 0.000
C51-C58 Malignant neoplasms of female genital organs
0.725 0.275 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.725 0.275 0.000
I35.1 Aortic (valve) insufficiency
0.725 0.275 0.000
R30-R39 Symptoms and signs involving the urinary system
0.724 0.276 0.000
M25.57 Pain in joint (Ankle and foot)
0.723 0.277 0.000
N10-N16 Renal tubulo-interstitial diseases
0.722 0.278 0.000
D46 Myelodysplastic syndromes
0.721 0.279 0.000
B37 Candidiasis
0.721 0.279 0.000
B95-B98 Bacterial, viral and other infectious agents
0.720 0.280 0.000
B25-B34 Other viral diseases
0.720 0.280 0.000
H49 Paralytic strabismus
0.720 0.280 0.000
R14 Flatulence and related conditions
0.719 0.281 0.000
C18.6 Descending colon
0.718 0.282 0.000
D37.4 Colon
0.718 0.282 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
M47.82 Other spondylosis (Cervical region)
0.716 0.284 0.000
C16 Malignant neoplasm of stomach
0.716 0.284 0.000
C18.4 Transverse colon
0.715 0.285 0.000
M91-M94 Chondropathies
0.714 0.286 0.000
N25-N29 Other disorders of kidney and ureter
0.714 0.286 0.000
N21 Calculus of lower urinary tract
0.714 0.286 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.713 0.287 0.000
C18.2 Ascending colon
0.712 0.288 0.000
C18.5 Splenic flexure
0.712 0.288 0.000
S82.6 Fracture of lateral malleolus
0.711 0.289 0.000
I77.1 Stricture of artery
0.711 0.289 0.000
M47.86 Other spondylosis (Lumbar region)
0.711 0.289 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.710 0.290 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.709 0.291 0.000
C77.3 Axillary and upper limb lymph nodes
0.709 0.291 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.708 0.292 0.000
I47.0 Reentry ventricular arrhythmia
0.708 0.292 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.706 0.294 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.706 0.294 0.000
Z93 Artificial opening status
0.705 0.295 0.000
T79-T79 Certain early complications of trauma
0.705 0.295 0.000
Q00-Q07 Congenital malformations of the nervous system
0.704 0.295 0.000
H40.2 Primary angle-closure glaucoma
0.704 0.296 0.000
R39 Other symptoms and signs involving the urinary system
0.703 0.297 0.000
S01 Open wound of head
0.702 0.298 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.702 0.298 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.702 0.298 0.000
M25.51 Pain in joint (Shoulder region)
0.700 0.299 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.699 0.300 0.000
W00-W19 Falls
0.699 0.301 0.000
M48 Other spondylopathies
0.699 0.301 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.699 0.301 0.000
H36 Retinal disorders in diseases classified elsewhere
0.697 0.302 0.000
Q61 Cystic kidney disease
0.697 0.303 0.000
L81 Other disorders of pigmentation
0.697 0.303 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.303 0.000
M34 Systemic sclerosis
0.696 0.303 0.000
M33 Dermatopolymyositis
0.696 0.303 0.000
M32 Systemic lupus erythematosus
0.696 0.303 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.303 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.696 0.304 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.695 0.304 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.695 0.304 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.695 0.304 0.000
C21 Malignant neoplasm of anus and anal canal
0.695 0.304 0.000
C17 Malignant neoplasm of small intestine
0.695 0.304 0.000
C23 Malignant neoplasm of gallbladder
0.695 0.304 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.695 0.305 0.000
S32 Fracture of lumbar spine and pelvis
0.695 0.305 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.694 0.306 0.000
N18.8 Other chronic renal failure
0.693 0.307 0.000
N18.2 Chronic kidney disease, stage 2
0.693 0.307 0.000
N18.1 Chronic kidney disease, stage 1
0.693 0.307 0.000
I46 Cardiac arrest
0.693 0.307 0.000
R18 Ascites
0.693 0.307 0.000
I62 Other nontraumatic intracranial haemorrhage
0.692 0.308 0.000
D45 Polycythaemia vera
0.692 0.308 0.000
M25.9 Joint disorder, unspecified
0.691 0.309 0.000
M25.3 Other instability of joint
0.691 0.309 0.000
M25.2 Flail joint
0.691 0.309 0.000
M25.1 Fistula of joint
0.691 0.309 0.000
I45.2 Bifascicular block
0.691 0.309 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.690 0.309 0.000
N18.9 Chronic renal failure, unspecified
0.690 0.310 0.000
S60-S69 Injuries to the wrist and hand
0.689 0.311 0.000
S50-S59 Injuries to the elbow and forearm
0.689 0.311 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.689 0.311 0.000
I78 Diseases of capillaries
0.688 0.311 0.000
I28 Other diseases of pulmonary vessels
0.688 0.312 0.000
V80-V89 Other land transport accidents
0.688 0.312 0.000
I35.8 Other aortic valve disorders
0.687 0.313 0.000
N40-N51 Diseases of male genital organs
0.687 0.313 0.000
C78.0 Secondary malignant neoplasm of lung
0.686 0.314 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.686 0.314 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.686 0.314 0.000
F60-F69 Disorders of adult personality and behaviour
0.685 0.315 0.000
I51.6 Cardiovascular disease, unspecified
0.685 0.315 0.000
I51.5 Myocardial degeneration
0.685 0.315 0.000
I51.4 Myocarditis, unspecified
0.685 0.315 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.685 0.315 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.685 0.315 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.685 0.315 0.000
I51.0 Cardiac septal defect, acquired
0.685 0.315 0.000
S70-S79 Injuries to the hip and thigh
0.684 0.315 0.000
Z95.2 Presence of prosthetic heart valve
0.684 0.316 0.000
M79.2 Neuralgia and neuritis, unspecified
0.684 0.316 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.683 0.317 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.683 0.317 0.000
C80.9 Malignant neoplasm, unspecified
0.682 0.318 0.000
B49 Unspecified mycosis
0.682 0.318 0.000
B15-B19 Viral hepatitis
0.682 0.318 0.000
I45.1 Other and unspecified right bundle-branch block
0.682 0.318 0.000
C25 Malignant neoplasm of pancreas
0.682 0.318 0.000
E16 Other disorders of pancreatic internal secretion
0.681 0.319 0.000
S80 Superficial injury of lower leg
0.681 0.319 0.000
B99-B99 Other infectious diseases
0.680 0.320 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.680 0.320 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.680 0.320 0.000
B65-B83 Helminthiases
0.680 0.320 0.000
B50-B64 Protozoal diseases
0.680 0.320 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.680 0.320 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.680 0.320 0.000
A80-A89 Viral infections of the central nervous system
0.680 0.320 0.000
A75-A79 Rickettsioses
0.680 0.320 0.000
A70-A74 Other diseases caused by chlamydiae
0.680 0.320 0.000
A65-A69 Other spirochaetal diseases
0.680 0.320 0.000
A20-A28 Certain zoonotic bacterial diseases
0.680 0.320 0.000
A15-A19 Tuberculosis
0.680 0.320 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.680 0.320 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.680 0.320 0.000
D38.1 Trachea, bronchus and lung
0.680 0.320 0.000
M77 Other enthesopathies
0.680 0.320 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.680 0.320 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.678 0.322 0.000
S08 Traumatic amputation of part of head
0.678 0.322 0.000
S07 Crushing injury of head
0.678 0.322 0.000
S05 Injury of eye and orbit
0.678 0.322 0.000
S04 Injury of cranial nerves
0.678 0.322 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.678 0.322 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.678 0.322 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.676 0.324 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.676 0.324 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.676 0.324 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.675 0.324 0.000
T93 Sequelae of injuries of lower limb
0.675 0.325 0.000
C77.5 Intrapelvic lymph nodes
0.675 0.325 0.000
T90 Sequelae of injuries of head
0.674 0.326 0.000
N35 Urethral stricture
0.674 0.326 0.000
M35.3 Polymyalgia rheumatica
0.674 0.326 0.000
E10.4 With neurological complications
0.674 0.326 0.000
A30-A49 Other bacterial diseases
0.674 0.326 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.673 0.327 0.000
M89 Other disorders of bone
0.673 0.327 0.000
V10-V19 Pedal cyclist injured in transport accident
0.673 0.327 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.672 0.327 0.000
M65-M68 Disorders of synovium and tendon
0.672 0.328 0.000
M50-M54 Other dorsopathies
0.672 0.328 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.672 0.328 0.000
C77.2 Intra-abdominal lymph nodes
0.671 0.328 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.671 0.329 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.671 0.329 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.671 0.329 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.671 0.329 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.671 0.329 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.671 0.329 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.671 0.329 0.000
T36 Poisoning by systemic antibiotics
0.671 0.329 0.000
M49 Spondylopathies in diseases classified elsewhere
0.671 0.329 0.000
N02 Recurrent and persistent haematuria
0.671 0.329 0.000
E22 Hyperfunction of pituitary gland
0.670 0.329 0.000
A08 Viral and other specified intestinal infections
0.670 0.330 0.000
W20-W49 Exposure to inanimate mechanical forces
0.670 0.330 0.000
H65-H75 Diseases of middle ear and mastoid
0.670 0.330 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.669 0.331 0.000
M10 Gout
0.669 0.331 0.000
Z98 Other postsurgical states
0.669 0.331 0.000
L90.0 Lichen sclerosus et atrophicus
0.669 0.331 0.000
S06 Intracranial injury
0.669 0.331 0.000
M84 Disorders of continuity of bone
0.668 0.331 0.000
H42 Glaucoma in diseases classified elsewhere
0.668 0.332 0.000
X50-X57 Overexertion, travel and privation
0.667 0.333 0.000
D61 Other aplastic anaemias
0.667 0.333 0.000
M80 Osteoporosis with pathological fracture
0.666 0.334 0.000
N17.8 Other acute renal failure
0.665 0.335 0.000
N17.2 Acute renal failure with medullary necrosis
0.665 0.335 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.665 0.335 0.000
N17.0 Acute renal failure with tubular necrosis
0.665 0.335 0.000
R10.0 Acute abdomen
0.665 0.335 0.000
I63.9 Cerebral infarction, unspecified
0.665 0.335 0.000
L20-L30 Dermatitis and eczema
0.665 0.335 0.000
C18.8 Overlapping lesion of colon
0.665 0.335 0.000
C18.3 Hepatic flexure
0.665 0.335 0.000
C18.1 Appendix
0.665 0.335 0.000
L72.0 Epidermal cyst
0.665 0.335 0.000
M81 Osteoporosis without pathological fracture
0.665 0.335 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.664 0.336 0.000
M79.5 Residual foreign body in soft tissue
0.664 0.336 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.664 0.336 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.663 0.337 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.663 0.337 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.662 0.338 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.662 0.338 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.662 0.338 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.662 0.338 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.662 0.338 0.000
M79.1 Myalgia
0.661 0.339 0.000
H33 Retinal detachments and breaks
0.660 0.340 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.660 0.340 0.000
M25.59 Pain in joint (Site unspecified)
0.660 0.340 0.000
M25.58 Pain in joint (Other)
0.660 0.340 0.000
M25.52 Pain in joint (Upper arm)
0.660 0.340 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.659 0.341 0.000
M13.98 Arthritis, unspecified (Other)
0.658 0.342 0.000
S20-S29 Injuries to the thorax
0.658 0.342 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.658 0.342 0.000
Q50-Q56 Congenital malformations of genital organs
0.658 0.342 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.658 0.342 0.000
Q35-Q37 Cleft lip and cleft palate
0.658 0.342 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.658 0.342 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.658 0.342 0.000
R47 Speech disturbances, not elsewhere classified
0.658 0.342 0.000
C79.6 Secondary malignant neoplasm of ovary
0.657 0.343 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.657 0.343 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.657 0.343 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.657 0.343 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.657 0.343 0.000
I08.8 Other multiple valve diseases
0.656 0.344 0.000
E29 Testicular dysfunction
0.656 0.344 0.000
M76 Enthesopathies of lower limb, excluding foot
0.656 0.344 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.656 0.344 0.000
I82 Other venous embolism and thrombosis
0.655 0.345 0.000
L89 Decubitus ulcer
0.655 0.345 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.654 0.346 0.000
T40.4 Other synthetic narcotics
0.654 0.346 0.000
M71 Other bursopathies
0.653 0.347 0.000
S10 Superficial injury of neck
0.652 0.348 0.000
E10.1 With ketoacidosis
0.652 0.348 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.652 0.348 0.000
M25.06 Haemarthrosis (Lower leg)
0.652 0.348 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.650 0.349 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.650 0.350 0.000
L10-L14 Bullous disorders
0.650 0.350 0.000
T11 Other injuries of upper limb, level unspecified
0.650 0.350 0.000
E83 Disorders of mineral metabolism
0.650 0.350 0.000
Z46 Fitting and adjustment of other devices
0.649 0.350 0.000
T87 Complications peculiar to reattachment and amputation
0.649 0.351 0.000
T86 Failure and rejection of transplanted organs and tissues
0.649 0.351 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.649 0.351 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.649 0.351 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.648 0.352 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.648 0.352 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.648 0.352 0.000
S82.4 Fracture of fibula alone
0.647 0.353 0.000
C77.8 Lymph nodes of multiple regions
0.647 0.353 0.000
E46 Unspecified protein-energy malnutrition
0.646 0.354 0.000
I72 Other aneurysm
0.645 0.354 0.000
I05 Rheumatic mitral valve diseases
0.645 0.354 0.000
M86 Osteomyelitis
0.645 0.354 0.000
M79.7 Fibromyalgia
0.645 0.355 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.644 0.356 0.000
I35.9 Aortic valve disorder, unspecified
0.644 0.356 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.644 0.356 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.644 0.356 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.643 0.357 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.643 0.357 0.000
M31 Other necrotising vasculopathies
0.642 0.357 0.000
H40.8 Other glaucoma
0.642 0.358 0.000
H40.6 Glaucoma secondary to drugs
0.642 0.358 0.000
H40.5 Glaucoma secondary to other eye disorders
0.642 0.358 0.000
H40.4 Glaucoma secondary to eye inflammation
0.642 0.358 0.000
H40.3 Glaucoma secondary to eye trauma
0.642 0.358 0.000
E13 Other specified diabetes mellitus
0.641 0.359 0.000
E12 Malnutrition-related diabetes mellitus
0.641 0.359 0.000
S09.8 Other specified injuries of head
0.641 0.359 0.000
S09.7 Multiple injuries of head
0.641 0.359 0.000
S09.2 Traumatic rupture of ear drum
0.641 0.359 0.000
S09.1 Injury of muscle and tendon of head
0.641 0.359 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.641 0.359 0.000
N23 Unspecified renal colic
0.641 0.359 0.000
L65 Other nonscarring hair loss
0.640 0.360 0.000
M79.62 Pain in limb (Upper arm)
0.640 0.360 0.000
Z95.0 Presence of cardiac pacemaker
0.639 0.361 0.000
R42 Dizziness and giddiness
0.639 0.361 0.000
S88 Traumatic amputation of lower leg
0.638 0.361 0.000
S87 Crushing injury of lower leg
0.638 0.361 0.000
S86 Injury of muscle and tendon at lower leg level
0.638 0.361 0.000
S85 Injury of blood vessels at lower leg level
0.638 0.361 0.000
S84 Injury of nerves at lower leg level
0.638 0.361 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.638 0.362 0.000
C73 Malignant neoplasm of thyroid gland
0.637 0.363 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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