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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9275659
log Bayes Factor = 44.8216
Chromosome 6   position 32,686,103  (GRCh37) Explore rs9275659 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.001 0.999
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
D80-D89 Certain disorders involving the immune mechanism
0.998 0.002 0.000
E16 Other disorders of pancreatic internal secretion
0.998 0.002 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.998 0.002 0.000
E16.2 Hypoglycaemia, unspecified
0.997 0.003 0.000
E10.1 With ketoacidosis
0.997 0.003 0.000
E03 Other hypothyroidism
0.996 0.004 0.000
R31 Unspecified haematuria
0.000 0.004 0.996
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.008 0.992
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
E20-E35 Disorders of other endocrine glands
0.992 0.008 0.000
E03.9 Hypothyroidism, unspecified
0.991 0.009 0.000
# Top node
0.991 0.009 0.000
M05-M14 Inflammatory polyarthropathies
0.005 0.009 0.986
M05 Seropositive rheumatoid arthritis
0.002 0.009 0.988
D50-D53 Nutritional anaemias
0.990 0.010 0.000
C85.1 B-cell lymphoma, unspecified
0.988 0.012 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.987 0.013 0.000
D50 Iron deficiency anaemia
0.986 0.014 0.000
D50.9 Iron deficiency anaemia, unspecified
0.986 0.014 0.000
D60-D64 Aplastic and other anaemias
0.985 0.015 0.000
D86 Sarcoidosis
0.984 0.016 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.983 0.017 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.982 0.018 0.000
D64 Other anaemias
0.979 0.021 0.000
D64.9 Anaemia, unspecified
0.975 0.025 0.000
E27 Other disorders of adrenal gland
0.973 0.027 0.000
E27.1 Primary adrenocortical insufficiency
0.972 0.028 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.029 0.971
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.970 0.030 0.000
D69 Purpura and other haemorrhagic conditions
0.966 0.034 0.000
M06.3 Rheumatoid nodule
0.000 0.034 0.966
D86.9 Sarcoidosis, unspecified
0.962 0.038 0.000
C81 Hodgkin's disease
0.960 0.040 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.960 0.040 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.956 0.044 0.000
E10.2 With renal complications
0.955 0.045 0.000
D69.6 Thrombocytopenia, unspecified
0.955 0.045 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.951 0.049 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.052 0.948
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.056 0.944
Q43 Other congenital malformations of intestine
0.942 0.058 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.062 0.938
Chapter XII Diseases of the skin and subcutaneous tissue
0.937 0.063 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.933 0.067 0.000
C84.5 Other and unspecified T-cell lymphomas
0.924 0.076 0.000
Chapter I Certain infectious and parasitic diseases
0.921 0.079 0.000
L10-L14 Bullous disorders
0.915 0.085 0.000
L50-L54 Urticaria and erythema
0.915 0.085 0.000
C81.9 Hodgkin's disease, unspecified
0.914 0.086 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.914 0.086 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.088 0.912
E23 Hypofunction and other disorders of pituitary gland
0.904 0.096 0.000
C88 Malignant immunoproliferative diseases
0.900 0.100 0.000
L13 Other bullous disorders
0.899 0.101 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.893 0.107 0.000
E24 Cushing's syndrome
0.891 0.109 0.000
D69.4 Other primary thrombocytopenia
0.889 0.111 0.000
C92 Myeloid leukaemia
0.889 0.111 0.000
E13 Other specified diabetes mellitus
0.888 0.112 0.000
L13.0 Dermatitis herpetiformis
0.888 0.112 0.000
E14 Unspecified diabetes mellitus
0.887 0.113 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.886 0.114 0.000
Q44.6 Cystic disease of liver
0.884 0.116 0.000
Chapter II Neoplasms
0.875 0.125 0.000
C83.7 Burkitt's tumour
0.874 0.126 0.000
L53 Other erythematous conditions
0.868 0.132 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.866 0.134 0.000
C91 Lymphoid leukaemia
0.865 0.135 0.000
E10.4 With neurological complications
0.863 0.137 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.854 0.146 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.147 0.852
D73 Diseases of spleen
0.852 0.148 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.157 0.843
Q43.8 Other specified congenital malformations of intestine
0.843 0.157 0.000
B15-B19 Viral hepatitis
0.841 0.159 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.840 0.160 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.840 0.160 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.165 0.835
C84.0 Mycosis fungoides
0.835 0.165 0.000
B07 Viral warts
0.827 0.173 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.826 0.174 0.000
Q60-Q64 Congenital malformations of the urinary system
0.826 0.174 0.000
E14.3 With ophthalmic complications
0.824 0.176 0.000
E23.2 Diabetes insipidus
0.823 0.177 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.178 0.822
L52 Erythema nodosum
0.821 0.179 0.000
C84.4 Peripheral T-cell lymphoma
0.820 0.180 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.817 0.183 0.000
D73.5 Infarction of spleen
0.813 0.187 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.188 0.812
Chapter XX External causes of morbidity and mortality
0.811 0.189 0.000
D69.2 Other nonthrombocytopenic purpura
0.810 0.190 0.000
C34 Malignant neoplasm of bronchus and lung
0.809 0.191 0.000
E13.9 Without complications
0.808 0.192 0.000
L40-L45 Papulosquamous disorders
0.804 0.196 0.001
D86.3 Sarcoidosis of skin
0.802 0.198 0.000
B25-B34 Other viral diseases
0.801 0.199 0.000
L51 Erythema multiforme
0.800 0.200 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.798 0.202 0.000
C83.3 Large cell (diffuse)
0.793 0.207 0.000
Q50-Q56 Congenital malformations of genital organs
0.792 0.208 0.000
C34.3 Lower lobe, bronchus or lung
0.792 0.208 0.000
Q38.7 Pharyngeal pouch
0.791 0.209 0.000
C83.1 Small cleaved cell (diffuse)
0.789 0.211 0.000
E10.7 With multiple complications
0.789 0.211 0.000
L53.9 Erythematous condition, unspecified
0.788 0.212 0.000
E03.8 Other specified hypothyroidism
0.788 0.212 0.000
D80 Immunodeficiency with predominantly antibody defects
0.787 0.213 0.000
L43 Lichen planus
0.786 0.213 0.000
D55-D59 Haemolytic anaemias
0.786 0.214 0.000
C81.1 Nodular sclerosis
0.786 0.214 0.000
Q00-Q07 Congenital malformations of the nervous system
0.785 0.215 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.781 0.219 0.000
C92.1 Chronic myeloid leukaemia
0.780 0.220 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.220 0.780
E10.0 With coma
0.778 0.222 0.000
D86.0 Sarcoidosis of lung
0.778 0.222 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.774 0.226 0.000
L43.9 Lichen planus, unspecified
0.774 0.226 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.227 0.773
E23.6 Other disorders of pituitary gland
0.773 0.227 0.000
L53.0 Toxic erythema
0.768 0.232 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.232 0.768
B02 Zoster [herpes zoster]
0.765 0.235 0.000
D83 Common variable immunodeficiency
0.764 0.236 0.000
V40-V49 Car occupant injured in transport accident
0.763 0.237 0.000
X20-X29 Contact with venomous animals and plants
0.763 0.237 0.000
C92.0 Acute myeloid leukaemia
0.761 0.239 0.000
E40-E46 Malnutrition
0.757 0.243 0.000
Q40 Other congenital malformations of upper alimentary tract
0.756 0.244 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.755 0.245 0.000
D89.1 Cryoglobulinaemia
0.755 0.245 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.755 0.245 0.000
E24.0 Pituitary-dependent Cushing's disease
0.755 0.245 0.000
A15-A19 Tuberculosis
0.752 0.248 0.000
D82 Immunodeficiency associated with other major defects
0.750 0.250 0.000
B16 Acute hepatitis B
0.750 0.250 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.749 0.251 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.749 0.251 0.000
E31 Polyglandular dysfunction
0.746 0.254 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.746 0.254 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.744 0.256 0.000
C91.1 Chronic lymphocytic leukaemia
0.742 0.258 0.000
C81.2 Mixed cellularity
0.742 0.258 0.000
Q44.5 Other congenital malformations of bile ducts
0.741 0.259 0.000
E24.9 Cushing's syndrome, unspecified
0.741 0.259 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.740 0.260 0.000
D69.9 Haemorrhagic condition, unspecified
0.740 0.260 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.739 0.261 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.735 0.265 0.000
M07 Psoriatic and enteropathic arthropathies
0.003 0.267 0.730
E10.5 With peripheral circulatory complications
0.732 0.268 0.000
C95 Leukaemia of unspecified cell type
0.729 0.271 0.000
D52 Folate deficiency anaemia
0.729 0.271 0.000
X23 Contact with hornets, wasps and bees
0.728 0.272 0.000
C93 Monocytic leukaemia
0.724 0.275 0.000
A80-A89 Viral infections of the central nervous system
0.723 0.277 0.000
Q43.0 Meckel's diverticulum
0.723 0.277 0.000
E14.8 With unspecified complications
0.722 0.278 0.000
C34.2 Middle lobe, bronchus or lung
0.722 0.278 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.722 0.278 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.721 0.279 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.721 0.279 0.000
L51.9 Erythema multiforme, unspecified
0.720 0.280 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.720 0.280 0.000
D86.8 Sarcoidosis of other and combined sites
0.720 0.280 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.719 0.281 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.718 0.282 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.716
M06.2 Rheumatoid bursitis
0.000 0.283 0.716
M06.1 Adult-onset Still's disease
0.000 0.283 0.716
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.716 0.283 0.000
C94 Other leukaemias of specified cell type
0.716 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
D81 Combined immunodeficiencies
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
C85.0 Lymphosarcoma
0.716 0.284 0.000
E06 Thyroiditis
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.715 0.285 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.286 0.714
E03.5 Myxoedema coma
0.714 0.286 0.000
E03.4 Atrophy of thyroid (acquired)
0.714 0.286 0.000
E03.3 Postinfectious hypothyroidism
0.714 0.286 0.000
E03.1 Congenital hypothyroidism without goitre
0.714 0.286 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.714 0.286 0.000
E28 Ovarian dysfunction
0.714 0.286 0.000
B34 Viral infection of unspecified site
0.713 0.287 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.289 0.711
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.289 0.711
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.289 0.711
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.289 0.711
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.289 0.711
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.289 0.711
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.289 0.711
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.289 0.711
E35 Disorders of endocrine glands in diseases classified elsewhere
0.711 0.289 0.000
E32 Diseases of thymus
0.711 0.289 0.000
E30 Disorders of puberty, not elsewhere classified
0.711 0.289 0.000
E25 Adrenogenital disorders
0.711 0.289 0.000
Q61 Cystic kidney disease
0.711 0.289 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.711 0.289 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.004 0.289 0.707
M08 Juvenile arthritis
0.004 0.289 0.707
M05.8 Other seropositive rheumatoid arthritis
0.002 0.290 0.709
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.002 0.290 0.709
M05.2 Rheumatoid vasculitis
0.002 0.290 0.709
M05.1 Rheumatoid lung disease
0.002 0.290 0.709
M05.0 Felty's syndrome
0.002 0.290 0.709
B01 Varicella [chickenpox]
0.710 0.290 0.000
E14.1 With ketoacidosis
0.709 0.291 0.000
D84 Other immunodeficiencies
0.708 0.292 0.000
X23.9 Unspecified place
0.708 0.292 0.000
Q35-Q37 Cleft lip and cleft palate
0.707 0.292 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.707 0.292 0.000
D50.1 Sideropenic dysphagia
0.707 0.293 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.707 0.293 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.706 0.294 0.000
E26 Hyperaldosteronism
0.705 0.295 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.705 0.295 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.705 0.295 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.704 0.296 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.704 0.296 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.704 0.296 0.000
C84.3 Lymphoepithelioid lymphoma
0.704 0.296 0.000
C84.2 T-zone lymphoma
0.704 0.296 0.000
C84.1 Sezary's diease
0.704 0.296 0.000
Q38.1 Ankyloglossia
0.704 0.296 0.000
C91.9 Lymphoid leukaemia, unspecified
0.702 0.298 0.000
D64.4 Congenital dyserythropoietic anaemia
0.702 0.298 0.000
D64.3 Other sideroblastic anaemias
0.702 0.298 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.702 0.298 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.702 0.298 0.000
D64.0 Hereditary sideroblastic anaemia
0.702 0.298 0.000
D61 Other aplastic anaemias
0.701 0.299 0.000
M14 Arthropathies in other diseases classified elsewhere
0.004 0.299 0.698
E10.6 With other specified complications
0.701 0.299 0.000
V48 Car occupant injured in noncollision transport accident
0.701 0.299 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.700 0.300 0.000
D73.1 Hypersplenism
0.700 0.300 0.000
E27.5 Adrenomedullary hyperfunction
0.698 0.302 0.000
E27.0 Other adrenocortical overactivity
0.698 0.302 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.697 0.303 0.000
Q39 Congenital malformations of oesophagus
0.695 0.304 0.000
D67 Hereditary factor IX deficiency
0.695 0.305 0.000
D69.8 Other specified haemorrhagic conditions
0.693 0.307 0.000
D69.1 Qualitative platelet defects
0.693 0.307 0.000
A30-A49 Other bacterial diseases
0.693 0.307 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.308 0.692
M06.38 Rheumatoid nodule (Other)
0.000 0.308 0.692
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.308 0.692
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.308 0.692
M06.33 Rheumatoid nodule (Forearm)
0.000 0.308 0.692
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.308 0.692
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.308 0.692
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.308 0.692
D73.4 Cyst of spleen
0.692 0.308 0.000
D70 Agranulocytosis
0.692 0.308 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.692 0.308 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
C83.0 Small cell (diffuse)
0.690 0.310 0.000
C81.7 Other Hodgkin's disease
0.688 0.312 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.688 0.312 0.000
C81.3 Lymphocytic depletion
0.688 0.312 0.000
B17 Other acute viral hepatitis
0.688 0.312 0.000
D89.3 Immune reconstitution syndrome
0.688 0.312 0.000
D53 Other nutritional anaemias
0.687 0.312 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.687 0.313 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.686 0.314 0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma
0.685 0.315 0.000
E23.7 Disorder of pituitary gland, unspecified
0.685 0.315 0.000
Q43.3 Congenital malformations of intestinal fixation
0.683 0.317 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.683 0.317 0.000
C34.8 Overlapping lesion of bronchus and lung
0.682 0.318 0.000
C83.6 Undifferentiated (diffuse)
0.682 0.318 0.000
C83.5 Lymphoblastic (diffuse)
0.682 0.318 0.000
C83.4 Immunoblastic (diffuse)
0.682 0.318 0.000
C83.2 Mixed small and large cell (diffuse)
0.682 0.318 0.000
E29 Testicular dysfunction
0.681 0.319 0.000
A65-A69 Other spirochaetal diseases
0.678 0.322 0.000
D86.1 Sarcoidosis of lymph nodes
0.678 0.322 0.000
M60-M63 Disorders of muscles
0.677 0.323 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.676 0.324 0.000
E50-E64 Other nutritional deficiencies
0.676 0.324 0.000
M15-M19 Arthrosis
0.676 0.324 0.000
Q43.7 Persistent cloaca
0.675 0.325 0.000
Q43.6 Congenital fistula of rectum and anus
0.675 0.325 0.000
Q43.5 Ectopic anus
0.675 0.325 0.000
Q43.4 Duplication of intestine
0.675 0.325 0.000
Q43.2 Other congenital functional disorders of colon
0.675 0.325 0.000
Q43.1 Hirschsprung's disease
0.675 0.325 0.000
M18 Arthrosis of first carpometacarpal joint
0.675 0.325 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.674 0.326 0.000
B00 Herpesviral [herpes simplex] infections
0.670 0.329 0.000
Q44.7 Other congenital malformations of liver
0.669 0.331 0.000
Q44.4 Choledochal cyst
0.669 0.331 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.669 0.331 0.000
Q44.2 Atresia of bile ducts
0.669 0.331 0.000
Q44.1 Other congenital malformations of gallbladder
0.669 0.331 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.669 0.331 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.331 0.669
E24.2 Drug-induced Cushing's syndrome
0.668 0.332 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.665 0.334 0.000
Q45 Other congenital malformations of digestive system
0.665 0.334 0.000
E07 Other disorders of thyroid
0.665 0.335 0.000
C33 Malignant neoplasm of trachea
0.665 0.335 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.664 0.336 0.000
E20 Hypoparathyroidism
0.663 0.337 0.000
L11 Other acantholytic disorders
0.663 0.337 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.663 0.337 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.662 0.338 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.662 0.338 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.660 0.340 0.000
A75-A79 Rickettsioses
0.660 0.340 0.000
A70-A74 Other diseases caused by chlamydiae
0.660 0.340 0.000
A20-A28 Certain zoonotic bacterial diseases
0.660 0.340 0.000
Q53 Undescended testicle
0.660 0.340 0.000
B02.2 Zoster with other nervous system involvement
0.660 0.340 0.000
E16.1 Other hypoglycaemia
0.659 0.341 0.000
E14.2 Withrenal complications
0.658 0.342 0.000
D62 Acute posthaemorrhagic anaemia
0.657 0.343 0.000
L10 Pemphigus
0.656 0.344 0.000
L14 Bullous disorders in diseases classified elsewhere
0.656 0.344 0.000
L54 Erythema in diseases classified elsewhere
0.656 0.344 0.000
Q61.3 Polycystic kidney, unspecified
0.656 0.344 0.000
D74 Methaemoglobinaemia
0.655 0.345 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.655 0.345 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.655 0.345 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.654 0.346 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.653 0.347 0.000
L12 Pemphigoid
0.653 0.347 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.652 0.347 0.000
D69.5 Secondary thrombocytopenia
0.650 0.350 0.000
C31 Malignant neoplasm of accessory sinuses
0.649 0.351 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.648 0.352 0.000
E23.1 Drug-induced hypopituitarism
0.648 0.352 0.000
C07 Malignant neoplasm of parotid gland
0.648 0.352 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.647 0.353 0.000
D64.8 Other specified anaemias
0.646 0.354 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.645 0.355 0.000
C88.7 Other malignant immunoproliferative diseases
0.645 0.355 0.000
C88.3 Immunoproliferative small intestinal disease
0.645 0.355 0.000
C88.2 Gamma heavy chain disease
0.645 0.355 0.000
C88.1 Alpha heavy chain disease
0.645 0.355 0.000
B15 Acute hepatitis A
0.645 0.355 0.000
L13.9 Bullous disorder, unspecified
0.644 0.355 0.000
L13.8 Other specified bullous disorders
0.644 0.355 0.000
L13.1 Subcorneal pustular dermatitis
0.644 0.355 0.000
M62 Other disorders of muscle
0.644 0.356 0.000
B35-B49 Mycoses
0.642 0.358 0.000
B25 Cytomegaloviral disease
0.641 0.359 0.000
D59 Acquired haemolytic anaemia
0.640 0.360 0.000
B06 Rubella [German measles]
0.640 0.360 0.000
B05 Measles
0.640 0.360 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.640 0.360 0.000
B04 Monkeypox
0.640 0.360 0.000
B03 Smallpox
0.640 0.360 0.000
Y42.7 Androgens and anabolic congeners
0.640 0.360 0.000
M12 Other specific arthropathies
0.004 0.361 0.635
Q64 Other congenital malformations of urinary system
0.639 0.361 0.000
E24.8 Other Cushing's syndrome
0.639 0.361 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.639 0.361 0.000
E24.3 Ectopic ACTH syndrome
0.639 0.361 0.000
E24.1 Nelson's syndrome
0.639 0.361 0.000
X30-X39 Exposure to forces of nature
0.638 0.362 0.000
C92.9 Myeloid leukaemia, unspecified
0.637 0.363 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.637 0.363 0.000
C92.7 Other myeloid leukaemia
0.637 0.363 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.637 0.363 0.000
C92.5 Acute myelomonocytic leukaemia
0.637 0.363 0.000
C92.3 Myeloid sarcoma
0.637 0.363 0.000
C92.2 Subacute myeloid leukaemia
0.637 0.363 0.000
E13.8 With unspecified complications
0.637 0.363 0.000
E13.7 With multiple complications
0.637 0.363 0.000
E13.6 With other specified complications
0.637 0.363 0.000
E13.5 With peripheral circulatory complications
0.637 0.363 0.000
E13.4 With neurological complications
0.637 0.363 0.000
E13.3 With ophthalmic complications
0.637 0.363 0.000
E13.2 With renal complications
0.637 0.363 0.000
E13.1 With ketoacidosis
0.637 0.363 0.000
E13.0 With coma
0.637 0.363 0.000
E14.7 With multiple complications
0.636 0.364 0.000
E14.0 With coma
0.636 0.364 0.000
Q38.8 Other congenital malformations of pharynx
0.635 0.364 0.000
Q38.6 Other congenital malformations of mouth
0.635 0.364 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.635 0.364 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.635 0.364 0.000
Q38.3 Other congenital malformations of tongue
0.635 0.364 0.000
Q38.2 Macroglossia
0.635 0.364 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.635 0.364 0.000
C91.0 Acute lymphoblastic leukaemia
0.635 0.365 0.000
X10-X19 Contact with heat and hot substances
0.634 0.366 0.000
M80-M85 Disorders of bone density and structure
0.633 0.367 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.632 0.368 0.000
C81.0 Lymphocytic predominance
0.632 0.368 0.000
D76.3 Other histiocytosis syndromes
0.630 0.370 0.000
E27.2 Addisonian crisis
0.630 0.370 0.000
Q55 Other congenital malformations of male genital organs
0.629 0.370 0.000
Y43 Primarily systemic agents
0.628 0.372 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.628 0.372 0.000
E14.5 With peripheral circulatory complications
0.628 0.372 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.628 0.372 0.000
A41 Other septicaemia
0.627 0.373 0.000
C91.5 Adult T-cell leukaemia
0.623 0.376 0.000
L53.3 Other chronic figurate erythema
0.622 0.378 0.000
L53.2 Erythema marginatum
0.622 0.378 0.000
L53.1 Erythema annulare centrifugum
0.622 0.378 0.000
E14.6 With other specified complications
0.621 0.379 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.621 0.379 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.620 0.380 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.620 0.380 0.000
C91.7 Other lymphoid leukaemia
0.620 0.380 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.620 0.380 0.000
C91.3 Prolymphocytic leukaemia
0.620 0.380 0.000
C91.2 Subacute lymphocytic leukaemia
0.620 0.380 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.620 0.380 0.000
Q74 Other congenital malformations of limb(s)
0.619 0.380 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.618 0.382 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.384 0.616
E27.9 Disorder of adrenal gland, unspecified
0.616 0.384 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.614 0.386 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.613 0.387 0.000
Y10-Y34 Event of undetermined intent
0.612 0.388 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.389 0.611
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.389 0.611
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.389 0.611
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.389 0.611
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.389 0.611
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.389 0.611
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.389 0.611
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.389 0.611
D73.9 Disease of spleen, unspecified
0.611 0.389 0.000
D73.8 Other diseases of spleen
0.611 0.389 0.000
D73.2 Chronic congestive splenomegaly
0.611 0.389 0.000
C04 Malignant neoplasm of floor of mouth
0.610 0.389 0.000
M62.8 Other specified disorders of muscle
0.610 0.390 0.000
L53.8 Other specified erythematous conditions
0.610 0.390 0.000
D73.3 Abscess of spleen
0.608 0.392 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.608 0.392 0.000
V20-V29 Motorcycle rider injured in transport accident
0.607 0.393 0.000
B19 Unspecified viral hepatitis
0.606 0.393 0.000
W50-W64 Exposure to animate mechanical forces
0.603 0.397 0.000
E34 Other endocrine disorders
0.602 0.398 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.602 0.398 0.000
B65-B83 Helminthiases
0.602 0.398 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.602 0.398 0.000
V90-V94 Water transport accidents
0.601 0.398 0.000
V48.4 Person injured while boarding or alighting
0.601 0.399 0.000
D75 Other diseases of blood and blood-forming organs
0.600 0.399 0.000
Y42.2 Antithyroid drugs
0.599 0.401 0.000
D58 Other hereditary haemolytic anaemias
0.597 0.403 0.000
D83.9 Common variable immunodeficiency, unspecified
0.596 0.403 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.596 0.403 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.595 0.405 0.000
V95-V97 Air and space transport accidents
0.595 0.405 0.000
Q04 Other congenital malformations of brain
0.594 0.405 0.000
M00-M03 Infectious arthropathies
0.594 0.406 0.000
Q03 Congenital hydrocephalus
0.593 0.407 0.000
Chapter XXII Codes for special purposes
0.593 0.407 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.592 0.408 0.000
A80 Acute poliomyelitis
0.591 0.409 0.000
C38.4 Pleura
0.590 0.409 0.000
B02.8 Zoster with other complications
0.590 0.410 0.000
E14.4 With neurological complications
0.589 0.411 0.000
M11 Other crystal arthropathies
0.004 0.412 0.584
X60-X84 Intentional self-harm
0.588 0.412 0.000
Y43.3 Other antineoplastic drugs
0.588 0.412 0.000
B34.9 Viral infection, unspecified
0.588 0.412 0.000
B91 Sequelae of poliomyelitis
0.588 0.412 0.000
A86 Unspecified viral encephalitis
0.586 0.414 0.000
D50.8 Other iron deficiency anaemias
0.586 0.414 0.000
V48.6 Passenger injured in traffic accident
0.585 0.415 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.582 0.418 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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