This research has been conducted with the support of the Wellcome Trust (
100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (
MC_UU_12010/3), the Oak Foundation (
OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (
204290/Z/16/Z) and the Li Ka Shing Foundation.
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