TreeWAS – Variant ID: rs10012953

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21.0 Primary hyperparathyroidism	0.562	0.438	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.540	0.460	0.000
E21.3 Hyperparathyroidism, unspecified	0.538	0.462	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.393	0.607	0.000
E21.4 Other specified disorders of parathyroid gland	0.387	0.613	0.000
E21.2 Other hyperparathyroidism	0.387	0.613	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.281	0.719	0.000
E20-E35 Disorders of other endocrine glands	0.220	0.780	0.000
E34 Other endocrine disorders	0.205	0.795	0.000
E34.9 Endocrine disorder, unspecified	0.187	0.813	0.000
E20 Hypoparathyroidism	0.187	0.813	0.000
E34.8 Other specified endocrine disorders	0.180	0.820	0.000
E24 Cushing's syndrome	0.175	0.825	0.000
E20.9 Hypoparathyroidism, unspecified	0.164	0.836	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.158	0.842	0.000
E32 Diseases of thymus	0.158	0.842	0.000
E31 Polyglandular dysfunction	0.158	0.842	0.000
E30 Disorders of puberty, not elsewhere classified	0.158	0.842	0.000
E25 Adrenogenital disorders	0.157	0.843	0.000
E26 Hyperaldosteronism	0.151	0.849	0.000
E34.5 Androgen resistance syndrome	0.147	0.853	0.000
E34.4 Constitutional tall stature	0.147	0.853	0.000
E34.3 Short stature, not elsewhere classified	0.147	0.853	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.147	0.853	0.000
E34.1 Other hypersecretion of intestinal hormones	0.147	0.853	0.000
E24.9 Cushing's syndrome, unspecified	0.146	0.854	0.000
E20.8 Other hypoparathyroidism	0.134	0.866	0.000
E20.1 Pseudohypoparathyroidism	0.134	0.866	0.000
E20.0 Idiopathic hypoparathyroidism	0.134	0.866	0.000
E24.2 Drug-induced Cushing's syndrome	0.130	0.870	0.000
E23 Hypofunction and other disorders of pituitary gland	0.128	0.872	0.000
E34.0 Carcinoid syndrome	0.128	0.872	0.000
E24.8 Other Cushing's syndrome	0.125	0.874	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.125	0.874	0.000
E24.3 Ectopic ACTH syndrome	0.125	0.874	0.000
E24.1 Nelson's syndrome	0.125	0.874	0.000
E27 Other disorders of adrenal gland	0.125	0.875	0.000
E28 Ovarian dysfunction	0.124	0.876	0.000
E24.0 Pituitary-dependent Cushing's disease	0.114	0.885	0.000
E26.9 Hyperaldosteronism, unspecified	0.114	0.886	0.000
E22 Hyperfunction of pituitary gland	0.114	0.886	0.000
E30.9 Disorder of puberty, unspecified	0.113	0.887	0.000
E30.8 Other disorders of puberty	0.113	0.887	0.000
E30.1 Precocious puberty	0.113	0.887	0.000
E30.0 Delayed puberty	0.113	0.887	0.000
E31.9 Polyglandular dysfunction, unspecified	0.113	0.887	0.000
E31.8 Other polyglandular dysfunction	0.113	0.887	0.000
E31.1 Polyglandular hyperfunction	0.113	0.887	0.000
E31.0 Autoimmune polyglandular failure	0.113	0.887	0.000
E32.9 Disease of thymus, unspecified	0.113	0.887	0.000
E32.8 Other diseases of thymus	0.113	0.887	0.000
E32.1 Abscess of thymus	0.113	0.887	0.000
E32.0 Persistent hyperplasia of thymus	0.113	0.887	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.113	0.887	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.113	0.887	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.113	0.887	0.000
E25.9 Adrenogenital disorder, unspecified	0.113	0.887	0.000
E25.8 Other adrenogenital disorders	0.113	0.887	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.112	0.888	0.000
E29 Testicular dysfunction	0.110	0.889	0.000
E26.8 Other hyperaldosteronism	0.109	0.891	0.000
E26.1 Secondary hyperaldosteronism	0.109	0.891	0.000
E23.6 Other disorders of pituitary gland	0.105	0.895	0.000
E27.1 Primary adrenocortical insufficiency	0.099	0.901	0.000
E27.8 Other specified disorders of adrenal gland	0.097	0.903	0.000
E26.0 Primary hyperaldosteronism	0.095	0.905	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.092	0.908	0.000
E23.1 Drug-induced hypopituitarism	0.092	0.908	0.000
E28.3 Primary ovarian failure	0.090	0.910	0.000
E27.5 Adrenomedullary hyperfunction	0.090	0.910	0.000
E27.0 Other adrenocortical overactivity	0.090	0.910	0.000
E28.9 Ovarian dysfunction, unspecified	0.089	0.911	0.000
E28.8 Other ovarian dysfunction	0.089	0.911	0.000
E28.1 Androgen excess	0.089	0.911	0.000
E28.0 Oestrogen excess	0.089	0.911	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.088	0.912	0.000
E27.2 Addisonian crisis	0.087	0.912	0.000
E23.0 Hypopituitarism	0.086	0.914	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.917	0.083
E22.9 Hyperfunction of pituitary gland, unspecified	0.082	0.918	0.000
E22.8 Other hyperfunction of pituitary gland	0.082	0.918	0.000
E22.1 Hyperprolactinaemia	0.081	0.919	0.000
E29.9 Testicular dysfunction, unspecified	0.079	0.921	0.000
E29.8 Other testicular dysfunction	0.079	0.921	0.000
E29.0 Testicular hyperfunction	0.079	0.921	0.000
E23.7 Disorder of pituitary gland, unspecified	0.078	0.922	0.000
E27.9 Disorder of adrenal gland, unspecified	0.077	0.922	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.929	0.071
E23.2 Diabetes insipidus	0.067	0.932	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.933	0.067
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.067	0.933	0.000
E22.0 Acromegaly and pituitary gigantism	0.064	0.936	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.937	0.063
E27.4 Other and unspecified adrenocortical insufficiency	0.054	0.946	0.000
E28.2 Polycystic ovarian syndrome	0.053	0.946	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.946	0.054
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.947	0.053
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.950	0.050
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.951	0.049
C79 Secondary malignant neoplasm of other sites	0.000	0.952	0.048
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.954	0.046
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.955	0.045
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.955	0.045
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.956	0.043
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.957	0.043
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.961	0.039
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.963	0.037
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.965	0.035
E29.1 Testicular hypofunction	0.031	0.968	0.001
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.971	0.029
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.971	0.029
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.973	0.027
F31.9 Bipolar affective disorder, unspecified	0.027	0.973	0.000
K62.1 Rectal polyp	0.027	0.973	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.975	0.025
C79.2 Secondary malignant neoplasm of skin	0.000	0.975	0.025
C76.0 Head, face and neck	0.000	0.977	0.023
C79.6 Secondary malignant neoplasm of ovary	0.000	0.977	0.023
C80 Malignant neoplasm without specification of site	0.000	0.978	0.022
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.979	0.021
C76.7 Other ill-defined sites	0.000	0.979	0.021
C76.5 Lower limb	0.000	0.979	0.021
C76.4 Upper limb	0.000	0.979	0.021
G93.3 Postviral fatigue syndrome	0.000	0.980	0.020
C76.1 Thorax	0.000	0.980	0.020
C76.2 Abdomen	0.000	0.981	0.019
C76.3 Pelvis	0.000	0.981	0.019
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.981	0.019
U89 Agent resistant to other and unspecified antibiotics	0.000	0.982	0.018
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.985	0.015
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.015	0.985	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.986	0.013
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.987	0.013
N93.0 Postcoital and contact bleeding	0.013	0.987	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.988	0.012
E88 Other metabolic disorders	0.012	0.988	0.000
N30.3 Trigonitis	0.000	0.988	0.012
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.989	0.011
Chapter IV Endocrine, nutritional and metabolic diseases	0.011	0.989	0.000
E06.9 Thyroiditis, unspecified	0.010	0.990	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.010	0.990	0.000
E06 Thyroiditis	0.010	0.990	0.000
U84 Resistance to other antimicrobial drugs	0.000	0.990	0.010
U83 Resistance to other antibiotics	0.000	0.990	0.010
U82 Resistance to betalactam antibiotics	0.000	0.990	0.010
U85 Resistance to antineoplastic drugs	0.000	0.990	0.010
E06.3 Autoimmune thyroiditis	0.010	0.990	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.009	0.991	0.000
E88.9 Metabolic disorder, unspecified	0.009	0.991	0.000
E88.3 Tumour lysis syndrome	0.009	0.991	0.000
E88.8 Other specified metabolic disorders	0.009	0.991	0.000
E00-E07 Disorders of thyroid gland	0.009	0.991	0.000
E88.2 Lipomatosis, not elsewhere classified	0.009	0.991	0.000
E66.8 Other obesity	0.009	0.991	0.000
E70-E90 Metabolic disorders	0.008	0.992	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.008	0.992	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.008	0.992	0.000
E85 Amyloidosis	0.008	0.992	0.000
E65-E68 Obesity and other hyperalimentation	0.008	0.992	0.000
E06.5 Other chronic thyroiditis	0.007	0.992	0.000
E06.4 Drug-induced thyroiditis	0.007	0.992	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.007	0.992	0.000
E06.1 Subacute thyroiditis	0.007	0.992	0.000
E06.0 Acute thyroiditis	0.007	0.992	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.992	0.007
H26.4 After-cataract	0.000	0.993	0.007
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.007	0.993	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.993	0.007
U82.8 Resistance to other betalactam antibiotics	0.000	0.993	0.007
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.993	0.007
U82.1 Resistance to methicillin	0.000	0.993	0.007
U82.0 Resistance to penicillin	0.000	0.993	0.007
U83.9 Resistance to unspecified antibiotic	0.000	0.993	0.007
U83.8 Resistance to other single specified antibiotic	0.000	0.993	0.007
U83.7 Resistance to multiple antibiotics	0.000	0.993	0.007
U83.2 Resistance to quinolones	0.000	0.993	0.007
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.993	0.007
U83.0 Resistance to vancomycin	0.000	0.993	0.007
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.993	0.007
U84.8 Resistance to other specified antimicrobial drug	0.000	0.993	0.007
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.993	0.007
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.993	0.007
U84.2 Resistance to antiviral drug(s)	0.000	0.993	0.007
U84.1 Resistance to antifungal drug(s)	0.000	0.993	0.007
U84.0 Resistance to antiparasitic drug(s)	0.000	0.993	0.007
E85.3 Secondary systemic amyloidosis	0.007	0.993	0.000
Z04.1 Examination and observation following transport accident	0.007	0.993	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.007	0.993	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.007	0.993	0.000
E66 Obesity	0.007	0.993	0.000
Q76 Congenital malformations of spine and bony thorax	0.007	0.993	0.000
Q74 Other congenital malformations of limb(s)	0.007	0.993	0.000
E05.8 Other thyrotoxicosis	0.007	0.993	0.000
Q65 Congenital deformities of hip	0.007	0.993	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.006	0.993	0.000
E00 Congenital iodine-deficiency syndrome	0.006	0.993	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.006	0.993	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.006	0.993	0.000
E70 Disorders of aromatic amino-acid metabolism	0.006	0.993	0.000
Q66 Congenital deformities of feet	0.006	0.994	0.000
E85.9 Amyloidosis, unspecified	0.006	0.994	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.006	0.994	0.000
E74 Other disorders of carbohydrate metabolism	0.006	0.994	0.000
Q79.6 Ehlers-Danlos syndrome	0.006	0.994	0.000
E84 Cystic fibrosis	0.006	0.994	0.000
E79 Disorders of purine and pyrimidine metabolism	0.006	0.994	0.000
E77 Disorders of glycoprotein metabolism	0.006	0.994	0.000
E76 Disorders of glycosaminoglycan metabolism	0.006	0.994	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.006	0.994	0.000
E72 Other disorders of amino-acid metabolism	0.006	0.994	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.006	0.994	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.006	0.994	0.000
E05.5 Thyroid crisis or storm	0.006	0.994	0.000
E05.4 Thyrotoxicosis factitia	0.006	0.994	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.006	0.994	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.006	0.994	0.000
D11.0 Parotid gland	0.006	0.994	0.000
E89.0 Postprocedural hypothyroidism	0.006	0.994	0.000
E80.6 Other disorders of bilirubin metabolism	0.006	0.994	0.000
E40-E46 Malnutrition	0.006	0.994	0.000
Q76.0 Spina bifida occulta	0.006	0.994	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.006	0.994	0.000
Q78 Other osteochondrodysplasias	0.006	0.994	0.000
Q70 Syndactyly	0.006	0.994	0.000
E67 Other hyperalimentation	0.006	0.994	0.000
E68 Sequelae of hyperalimentation	0.006	0.994	0.000
E85.8 Other amyloidosis	0.006	0.994	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.006	0.994	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.006	0.994	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.006	0.994	0.000
S06.2 Diffuse brain injury	0.006	0.994	0.000
E85.4 Organ-limited amyloidosis	0.006	0.994	0.000
E80.1 Porphyria cutanea tarda	0.006	0.994	0.000
G12.2 Motor neuron disease	0.006	0.994	0.000
Q65.8 Other congenital deformities of hip	0.006	0.994	0.000
E89.2 Postprocedural hypoparathyroidism	0.006	0.994	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.005	0.994	0.000
E73 Lactose intolerance	0.005	0.994	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.994	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.994	0.000
Q73 Reduction defects of unspecified limb	0.005	0.994	0.000
Q72 Reduction defects of lower limb	0.005	0.994	0.000
Q71 Reduction defects of upper limb	0.005	0.994	0.000
Q69 Polydactyly	0.005	0.994	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.994	0.000
Q76.5 Cervical rib	0.005	0.994	0.000
Q74.1 Congenital malformation of knee	0.005	0.994	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.005	0.995	0.000
I50.0 Congestive heart failure	0.000	0.995	0.005
E89.4 Postprocedural ovarian failure	0.005	0.995	0.000
Q66.2 Metatarsus varus	0.005	0.995	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.005	0.995	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.005	0.995	0.000
Q67.6 Pectus excavatum	0.005	0.995	0.000
Q66.3 Other congenital varus deformities of feet	0.005	0.995	0.000
E70.3 Albinism	0.005	0.995	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.005	0.995	0.000
E80.5 Crigler-Najjar syndrome	0.005	0.995	0.000
E80.3 Defects of catalase and peroxydase	0.005	0.995	0.000
E80.0 Hereditary erythropoietic porphyria	0.005	0.995	0.000
E74.0 Glycogen storage disease	0.005	0.995	0.000
Q76.1 Klippel-Feil syndrome	0.005	0.995	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.005	0.995	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.005	0.995	0.000
E89.5 Postprocedural testicular hypofunction	0.005	0.995	0.000
E89.1 Postprocedural hypoinsulinaemia	0.005	0.995	0.000
E66.1 Drug-induced obesity	0.005	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.005	0.995	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.005	0.995	0.000
Q76.8 Other congenital malformations of bony thorax	0.005	0.995	0.000
Q76.7 Congenital malformation of sternum	0.005	0.995	0.000
Q76.6 Other congenital malformations of ribs	0.005	0.995	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.005	0.995	0.000
Q76.2 Congenital spondylolisthesis	0.005	0.995	0.000
Q66.0 Talipes equinovarus	0.005	0.995	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.005	0.995	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.005	0.995	0.000
Q74.3 Arthrogryposis multiplex congenita	0.005	0.995	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.995	0.005
Q65.9 Congenital deformity of hip, unspecified	0.005	0.995	0.000
Q65.6 Unstable hip	0.005	0.995	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.005	0.995	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.005	0.995	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.005	0.995	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.005	0.995	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.005	0.995	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.995	0.005
E50-E64 Other nutritional deficiencies	0.005	0.995	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.005	0.995	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.005	0.995	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.005	0.995	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.005	0.995	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.995	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.005	0.995	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.005	0.995	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.005	0.995	0.000
E66.0 Obesity due to excess calories	0.005	0.995	0.000
E80.4 Gilbert's syndrome	0.005	0.995	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.005	0.995	0.000
Q79.5 Other congenital malformations of abdominal wall	0.005	0.995	0.000
Q79.4 Prune belly syndrome	0.005	0.995	0.000
Q79.3 Gastroschisis	0.005	0.995	0.000
Q79.2 Exomphalos	0.005	0.995	0.000
Q79.1 Other congenital malformations of diaphragm	0.005	0.995	0.000
Q79.0 Congenital diaphragmatic hernia	0.005	0.995	0.000
Q78.0 Osteogenesis imperfecta	0.005	0.995	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.005	0.995	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.005	0.995	0.000
E70.2 Disorders of tyrosine metabolism	0.005	0.995	0.000
E70.1 Other hyperphenylalaninaemias	0.005	0.995	0.000
E70.0 Classical phenylketonuria	0.005	0.995	0.000
Q67.5 Congenital deformity of spine	0.005	0.995	0.000
Q66.9 Congenital deformity of feet, unspecified	0.005	0.995	0.000
Q66.7 Pes cavus	0.005	0.995	0.000
Q66.5 Congenital pes planus	0.005	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.005	0.995	0.000
Q66.1 Talipes calcaneovarus	0.005	0.995	0.000
Q70.3 Webbed toes	0.005	0.995	0.000
Chapter XXII Codes for special purposes	0.000	0.995	0.005
Q66.8 Other congenital deformities of feet	0.005	0.995	0.000
Q67.8 Other congenital deformities of chest	0.005	0.995	0.000
Q67.7 Pectus carinatum	0.005	0.995	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.005	0.995	0.000
Q67.3 Plagiocephaly	0.005	0.995	0.000
Q67.2 Dolichocephaly	0.005	0.995	0.000
Q67.1 Compression facies	0.005	0.995	0.000
Q67.0 Facial asymmetry	0.005	0.995	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.005	0.995	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.005	0.995	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.005	0.995	0.000
E74.2 Disorders of galactose metabolism	0.005	0.995	0.000
E74.1 Disorders of fructose metabolism	0.005	0.995	0.000
E71.3 Disorders of fatty-acid metabolism	0.004	0.995	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.004	0.995	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.004	0.995	0.000
E71.0 Maple-syrup-urine disease	0.004	0.995	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.004	0.995	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.004	0.995	0.000
E72.5 Disorders of glycine metabolism	0.004	0.995	0.000
E72.4 Disorders of ornithine metabolism	0.004	0.995	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.004	0.995	0.000
E72.2 Disorders of urea cycle metabolism	0.004	0.995	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.004	0.995	0.000
E72.0 Disorders of amino-acid transport	0.004	0.995	0.000
E75.6 Lipid storage disorder, unspecified	0.004	0.995	0.000
E75.5 Other lipid storage disorders	0.004	0.995	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.004	0.995	0.000
E75.3 Sphingolipidosis, unspecified	0.004	0.995	0.000
E75.2 Other sphingolipidosis	0.004	0.995	0.000
E75.1 Other gangliosidosis	0.004	0.995	0.000
E75.0 GM2 gangliosidosis	0.004	0.995	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.004	0.995	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.004	0.995	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.004	0.995	0.000
E76.2 Other mucopolysaccharidoses	0.004	0.995	0.000
E76.1 Mucopolysaccharidosis, type II	0.004	0.995	0.000
E76.0 Mucopolysaccharidosis, type I	0.004	0.995	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.004	0.995	0.000
E77.8 Other disorders of glycoprotein metabolism	0.004	0.995	0.000
E77.1 Defects in glycoprotein degradation	0.004	0.995	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.004	0.995	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.004	0.995	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.004	0.995	0.000
E79.1 Lesch-Nyhan syndrome	0.004	0.995	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.004	0.995	0.000
E84.9 Cystic fibrosis, unspecified	0.004	0.995	0.000
E84.8 Cystic fibrosis with other manifestations	0.004	0.995	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.004	0.995	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.004	0.995	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.995	0.005
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.995	0.005
E80.2 Other porphyria	0.004	0.995	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.004	0.995	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.004	0.995	0.000
E45 Retarded development following protein-energy malnutrition	0.004	0.995	0.000
E43 Unspecified severe protein-energy malnutrition	0.004	0.995	0.000
E42 Marasmic kwashiorkor	0.004	0.995	0.000
E41 Nutritional marasmus	0.004	0.995	0.000
E40 Kwashiorkor	0.004	0.995	0.000
E15 Nondiabetic hypoglycaemic coma	0.004	0.995	0.000
H53.0 Amblyopia ex anopsia	0.000	0.995	0.005
Q79.8 Other congenital malformations of musculoskeletal system	0.004	0.995	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.004	0.995	0.000
Q78.8 Other specified osteochondrodysplasias	0.004	0.995	0.000
Q78.6 Multiple congenital exostoses	0.004	0.995	0.000
Q78.5 Metaphyseal dysplasia	0.004	0.995	0.000
Q78.4 Enchondromatosis	0.004	0.995	0.000
Q78.3 Progressive diaphyseal dysplasia	0.004	0.995	0.000
Q78.2 Osteopetrosis	0.004	0.995	0.000
Q78.1 Polyostotic fibrous dysplasia	0.004	0.995	0.000
Q70.9 Syndactyly, unspecified	0.004	0.995	0.000
Q70.4 Polysyndactyly	0.004	0.995	0.000
Q70.2 Fused toes	0.004	0.995	0.000
Q70.1 Webbed fingers	0.004	0.995	0.000
Q70.0 Fused fingers	0.004	0.995	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.004	0.995	0.000
E67.8 Other specified hyperalimentation	0.004	0.996	0.000
E67.3 Hypervitaminosis D	0.004	0.996	0.000
E67.2 Megavitamin-B6 syndrome	0.004	0.996	0.000
E67.1 Hypercarotenaemia	0.004	0.996	0.000
E67.0 Hypervitaminosis A	0.004	0.996	0.000
G93.6 Cerebral oedema	0.000	0.996	0.004
S06.21 Diffuse brain injury (with open intracranial wound)	0.004	0.996	0.000
E05.9 Thyrotoxicosis, unspecified	0.004	0.996	0.000
E73.8 Other lactose intolerance	0.004	0.996	0.000
E73.1 Secondary lactase deficiency	0.004	0.996	0.000
E73.0 Congenital lactase deficiency	0.004	0.996	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.004	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.004	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.004	0.996	0.000
Q68.3 Congenital bowing of femur	0.004	0.996	0.000
Q68.2 Congenital deformity of knee	0.004	0.996	0.000
Q68.1 Congenital deformity of hand	0.004	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.004	0.996	0.000
Q69.9 Polydactyly, unspecified	0.004	0.996	0.000
Q69.2 Accessory toe(s)	0.004	0.996	0.000
Q69.1 Accessory thumb(s)	0.004	0.996	0.000
Q69.0 Accessory finger(s)	0.004	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.004	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.004	0.996	0.000
Q71.6 Lobster-claw hand	0.004	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.004	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.004	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.004	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.004	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.004	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.004	0.996	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.004	0.996	0.000
Q72.8 Other reduction defects of lower limb(s)	0.004	0.996	0.000
Q72.7 Split foot	0.004	0.996	0.000
Q72.6 Longitudinal reduction defect of fibula	0.004	0.996	0.000
Q72.5 Longitudinal reduction defect of tibia	0.004	0.996	0.000
Q72.4 Longitudinal reduction defect of femur	0.004	0.996	0.000
Q72.3 Congenital absence of foot and toe(s)	0.004	0.996	0.000
Q72.2 Congenital absence of both lower leg and foot	0.004	0.996	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.004	0.996	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.004	0.996	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.004	0.996	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.004	0.996	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.004	0.996	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.004	0.996	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.004	0.996	0.000
Q75.5 Oculomandibular dysostosis	0.004	0.996	0.000
Q75.4 Mandibulofacial dysostosis	0.004	0.996	0.000
Q75.3 Macrocephaly	0.004	0.996	0.000
Q75.2 Hypertelorism	0.004	0.996	0.000
Q75.1 Craniofacial dysostosis	0.004	0.996	0.000
Q75.0 Craniosynostosis	0.004	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.004	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.004	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.004	0.996	0.000
Q77.5 Diastrophic dysplasia	0.004	0.996	0.000
Q77.4 Achondroplasia	0.004	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.004	0.996	0.000
Q77.2 Short rib syndrome	0.004	0.996	0.000
Q77.1 Thanatophoric short stature	0.004	0.996	0.000
Q77.0 Achondrogenesis	0.004	0.996	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.004	0.996	0.000
V18.0 Driver injured in nontraffic accident	0.004	0.996	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.996	0.004
E74.3 Other disorders of intestinal carbohydrate absorption	0.004	0.996	0.000
S06.5 Traumatic subdural haemorrhage	0.004	0.996	0.000
G93 Other disorders of brain	0.000	0.996	0.004
Z51.8 Other specified medical care	0.000	0.996	0.004
S06 Intracranial injury	0.004	0.996	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.004	0.996	0.000
E58 Dietary calcium deficiency	0.004	0.996	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.996	0.004
E64 Sequelae of malnutrition and other nutritional deficiencies	0.004	0.996	0.000
E63 Other nutritional deficiencies	0.004	0.996	0.000
E56 Other vitamin deficiencies	0.004	0.996	0.000
E51 Thiamine deficiency	0.004	0.996	0.000
E50 Vitamin A deficiency	0.004	0.996	0.000
E60 Dietary zinc deficiency	0.004	0.996	0.000
E59 Dietary selenium deficiency	0.004	0.996	0.000
E54 Ascorbic acid deficiency	0.004	0.996	0.000
E52 Niacin deficiency [pellagra]	0.004	0.996	0.000
S06.4 Epidural haemorrhage	0.004	0.996	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.996	0.004
S06.40 Epidural haemorrhage (without open intracranial wound)	0.004	0.996	0.000
E65 Localised adiposity	0.003	0.996	0.000
G93.4 Encephalopathy, unspecified	0.000	0.996	0.004
E73.9 Lactose intolerance, unspecified	0.003	0.996	0.000
E44.1 Mild protein-energy malnutrition	0.003	0.996	0.000
E44.0 Moderate protein-energy malnutrition	0.003	0.996	0.000
E07 Other disorders of thyroid	0.003	0.996	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.003	0.997	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.997	0.003
E61 Deficiency of other nutrient elements	0.003	0.997	0.000
S06.1 Traumatic cerebral oedema	0.003	0.997	0.000
E55 Vitamin D deficiency	0.002	0.997	0.001
S71.1 Open wound of thigh	0.003	0.997	0.000
G58.8 Other specified mononeuropathies	0.000	0.997	0.003
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.997	0.003
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
E10.9 Without complications	0.000	0.997	0.003
G93.7 Reye's syndrome	0.000	0.997	0.003
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.997	0.003
E89.3 Postprocedural hypopituitarism	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations