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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10034228
log Bayes Factor = 0.879762
Chromosome 4   position 112,611,750  (GRCh37) Explore rs10034228 on Ensembl!
Variant rs10034228 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H18 Other disorders of cornea
0.000 0.222 0.778
H18.8 Other specified disorders of cornea
0.000 0.242 0.758
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.248 0.752
H18.9 Disorder of cornea, unspecified
0.000 0.258 0.742
H21 Other disorders of iris and ciliary body
0.000 0.264 0.736
H18.4 Corneal degeneration
0.000 0.271 0.729
H21.8 Other specified disorders of iris and ciliary body
0.000 0.273 0.727
H18.2 Other corneal oedema
0.000 0.302 0.698
H20 Iridocyclitis
0.000 0.348 0.652
H18.0 Corneal pigmentations and deposits
0.000 0.366 0.634
H17 Corneal scars and opacities
0.000 0.418 0.582
H21.9 Disorder of iris and ciliary body, unspecified
0.000 0.425 0.575
H18.6 Keratoconus
0.000 0.431 0.569
H18.3 Changes in corneal membranes
0.000 0.441 0.559
H18.7 Other corneal deformities
0.000 0.442 0.558
H20.8 Other iridocyclitis
0.000 0.443 0.557
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.444 0.555
H21.4 Pupillary membranes
0.000 0.455 0.545
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.462 0.537
H21.2 Degeneration of iris and ciliary body
0.000 0.466 0.534
H15 Disorders of sclera
0.000 0.471 0.528
H21.3 Cyst of iris, ciliary body and anterior chamber
0.000 0.473 0.527
H20.1 Chronic iridocyclitis
0.000 0.476 0.524
H20.9 Iridocyclitis, unspecified
0.000 0.489 0.511
H18.1 Bullous keratopathy
0.000 0.489 0.511
H18.5 Hereditary corneal dystrophies
0.000 0.499 0.501
H21.1 Other vascular disorders of iris and ciliary body
0.000 0.516 0.484
H21.5 Other adhesions and disruptions of iris and ciliary body
0.000 0.522 0.478
H16 Keratitis
0.000 0.530 0.470
H21.0 Hyphaema
0.000 0.532 0.467
H20.2 Lens-induced iridocyclitis
0.000 0.533 0.467
H17.8 Other corneal scars and opacities
0.000 0.540 0.460
C78.0 Secondary malignant neoplasm of lung
0.437 0.563 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.000 0.567 0.433
H17.1 Other central corneal opacity
0.000 0.583 0.417
H17.0 Adherent leukoma
0.000 0.583 0.417
H17.9 Corneal scar and opacity, unspecified
0.000 0.584 0.416
H16.2 Keratoconjunctivitis
0.000 0.590 0.410
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.000 0.602 0.398
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.000 0.602 0.398
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.000 0.602 0.398
H20.0 Acute and subacute iridocyclitis
0.000 0.614 0.386
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.614 0.385
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.000 0.614 0.385
H22.1 Iridocyclitis in other diseases classified elsewhere
0.000 0.616 0.383
H15.1 Episcleritis
0.000 0.617 0.383
H15.9 Disorder of sclera, unspecified
0.000 0.621 0.379
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.000 0.626 0.374
H15.0 Scleritis
0.000 0.626 0.374
H15.8 Other disorders of sclera
0.000 0.631 0.369
H16.4 Corneal neovascularisation
0.000 0.663 0.337
H16.3 Interstitial and deep keratitis
0.000 0.663 0.337
H16.9 Keratitis, unspecified
0.000 0.682 0.318
H16.8 Other keratitis
0.000 0.695 0.305
H16.1 Other superficial keratitis without conjunctivitis
0.000 0.698 0.302
Chapter VII Diseases of the eye and adnexa
0.000 0.705 0.295
H25-H28 Disorders of lens
0.000 0.721 0.279
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.722 0.278
H27 Other disorders of lens
0.000 0.748 0.252
H26 Other cataract
0.000 0.748 0.252
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.748 0.252
H26.4 After-cataract
0.000 0.750 0.250
H46 Optic neuritis
0.000 0.759 0.241
H47.0 Disorders of optic nerve, not elsewhere classified
0.000 0.764 0.236
H27.8 Other specified disorders of lens
0.000 0.766 0.234
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.769 0.231
H16.0 Corneal ulcer
0.000 0.777 0.223
H52 Disorders of refraction and accommodation
0.000 0.780 0.220
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.788 0.212
H55-H59 Other disorders of eye and adnexa
0.000 0.798 0.202
H43-H45 Disorders of vitreous body and globe
0.000 0.798 0.202
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.800 0.199
H27.1 Dislocation of lens
0.000 0.804 0.196
H52.3 Anisometropia and aniseikonia
0.000 0.808 0.192
H52.1 Myopia
0.000 0.809 0.191
H26.2 Complicated cataract
0.000 0.812 0.188
H47.1 Papilloedema, unspecified
0.000 0.812 0.188
H52.2 Astigmatism
0.000 0.812 0.188
H55 Nystagmus and other irregular eye movements
0.000 0.817 0.183
H27.9 Disorder of lens, unspecified
0.000 0.819 0.181
H47.7 Disorder of visual pathways, unspecified
0.000 0.819 0.181
H47.6 Disorders of visual cortex
0.000 0.819 0.181
H47.5 Disorders of other visual pathways
0.000 0.819 0.181
H47.4 Disorders of optic chiasm
0.000 0.819 0.181
H26.1 Traumatic cataract
0.000 0.819 0.180
H52.0 Hypermetropia
0.000 0.821 0.179
H44 Disorders of globe
0.000 0.826 0.174
H47.3 Other disorders of optic disk
0.000 0.828 0.172
H47.2 Optic atrophy
0.000 0.832 0.168
H26.0 Infantile, juvenile and presenile cataract
0.000 0.832 0.167
H49 Paralytic strabismus
0.000 0.833 0.167
H28.0 Diabetic cataract
0.000 0.835 0.165
H26.3 Drug-induced cataract
0.000 0.838 0.162
H26.8 Other specified cataract
0.000 0.841 0.159
H52.6 Other disorders of refraction
0.000 0.842 0.158
H52.5 Disorders of accommodation
0.000 0.842 0.158
H27.0 Aphakia
0.000 0.842 0.158
H25 Senile cataract
0.000 0.846 0.154
H49.9 Paralytic strabismus, unspecified
0.000 0.847 0.153
H28.8 Other disorders of lens in diseases classified elsewhere
0.000 0.848 0.152
H28.2 Cataract in other diseases classified elsewhere
0.000 0.848 0.152
H28.1 Cataract in other endocrine, nutritional and metabolic diseases
0.000 0.848 0.152
H10-H13 Disorders of conjunctiva
0.000 0.848 0.152
H52.4 Presbyopia
0.000 0.849 0.151
H51 Other disorders of binocular movement
0.000 0.851 0.149
H04.1 Other disorders of lachrymal gland
0.000 0.854 0.146
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.854 0.146
H25.8 Other senile cataract
0.000 0.855 0.145
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.855 0.145
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.000 0.855 0.145
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere
0.000 0.857 0.143
H48.1 Retrobulbar neuritis in diseases classified elsewhere
0.000 0.857 0.143
H48.0 Optic atrophy in diseases classified elsewhere
0.000 0.857 0.143
H04 Disorders of lachrymal system
0.000 0.861 0.139
H44.0 Purulent endophthalmitis
0.000 0.861 0.139
H49.0 Third [oculomotor] nerve palsy
0.000 0.862 0.138
H40-H42 Glaucoma
0.000 0.862 0.138
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.138 0.862 0.000
H44.8 Other disorders of globe
0.000 0.867 0.133
H44.9 Disorder of globe, unspecified
0.000 0.867 0.133
H44.2 Degenerative myopia
0.000 0.868 0.132
H44.1 Other endophthalmitis
0.000 0.870 0.130
C78.2 Secondary malignant neoplasm of pleura
0.126 0.874 0.000
H44.5 Degenerated conditions of globe
0.000 0.875 0.125
H44.7 Retained (old) intraocular foreign body, nonmagnetic
0.000 0.875 0.125
H44.6 Retained (old) intraocular foreign body, magnetic
0.000 0.875 0.125
H44.3 Other degenerative disorders of globe
0.000 0.875 0.125
H44.4 Hypotony of eye
0.000 0.878 0.122
C78.7 Secondary malignant neoplasm of liver
0.121 0.879 0.000
H49.8 Other paralytic strabismus
0.000 0.880 0.120
H49.3 Total (external) ophthalmoplegia
0.000 0.880 0.120
H52.7 Disorder of refraction, unspecified
0.000 0.881 0.119
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.884 0.116
H04.8 Other disorders of lachrymal system
0.000 0.884 0.116
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.884 0.116
H30-H36 Disorders of choroid and retina
0.000 0.886 0.114
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.887 0.113
H25.2 Senile cataract, morgagnian type
0.000 0.889 0.111
H53-H54 Visual disturbances and blindness
0.000 0.890 0.110
H13 Disorders of conjunctiva in diseases classified elsewhere
0.000 0.891 0.109
H59.8 Other postprocedural disorders of eye and adnexa
0.000 0.891 0.109
H51.9 Disorder of binocular movement, unspecified
0.000 0.893 0.107
H51.8 Other specified disorders of binocular movement
0.000 0.893 0.107
H51.1 Convergence insufficiency and excess
0.000 0.893 0.107
H51.0 Palsy of conjugate gaze
0.000 0.893 0.107
H04.6 Other changes in lachrymal passages
0.000 0.893 0.107
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.104 0.896 0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.896 0.104
H45.1 Endophthalmitis in diseases classified elsewhere
0.000 0.896 0.104
H45.0 Vitreous haemorrhage in diseases classified elsewhere
0.000 0.896 0.104
H04.4 Chronic inflammation of lachrymal passages
0.000 0.897 0.103
H59.9 Postprocedural disorder of eye and adnexa, unspecified
0.000 0.897 0.102
H04.0 Dacryoadenitis
0.000 0.900 0.100
H42 Glaucoma in diseases classified elsewhere
0.000 0.901 0.099
H59.0 Vitreous syndrome following cataract surgery
0.000 0.901 0.099
H31 Other disorders of choroid
0.000 0.903 0.097
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.096 0.904 0.000
H49.4 Progressive external ophthalmoplegia
0.000 0.904 0.096
H06.2 Dysthyroid exophthalmos
0.000 0.905 0.095
C78.1 Secondary malignant neoplasm of mediastinum
0.095 0.905 0.000
H11 Other disorders of conjunctiva
0.000 0.907 0.093
H33 Retinal detachments and breaks
0.000 0.907 0.093
H31.8 Other specified disorders of choroid
0.000 0.908 0.092
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.000 0.910 0.090
H51.2 Internuclear ophthalmoplegia
0.000 0.910 0.089
H49.1 Fourth [trochlear] nerve palsy
0.000 0.914 0.086
H04.9 Disorder of lachrymal system, unspecified
0.000 0.914 0.086
H33.0 Retinal detachment with retinal break
0.000 0.914 0.086
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.916 0.084
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.916 0.084
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.916 0.084
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere
0.000 0.917 0.083
H58.1 Visual disturbances in diseases classified elsewhere
0.000 0.917 0.083
H58.0 Anomalies of pupillary function in diseases classified elsewhere
0.000 0.917 0.083
H26.9 Cataract, unspecified
0.000 0.918 0.082
H25.1 Senile nuclear cataract
0.000 0.918 0.082
H00 Hordeolum and chalazion
0.000 0.918 0.082
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.918 0.082
H33.2 Serous retinal detachment
0.000 0.918 0.082
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.000 0.919 0.081
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere
0.000 0.919 0.081
H30 Chorioretinal inflammation
0.000 0.920 0.080
H13.8 Other disorders of conjunctiva in diseases classified elsewhere
0.000 0.921 0.078
H13.3 Ocular pemphigoid
0.000 0.921 0.078
H13.2 Conjunctivitis in other diseases classified elsewhere
0.000 0.921 0.078
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere
0.000 0.921 0.078
H13.0 Filarial infection of conjunctiva
0.000 0.921 0.078
H10 Conjunctivitis
0.000 0.923 0.077
H11.1 Conjunctival degenerations and deposits
0.000 0.923 0.077
H11.9 Disorder of conjunctiva, unspecified
0.000 0.925 0.075
H31.1 Choroidal degeneration
0.000 0.925 0.074
H57 Other disorders of eye and adnexa
0.000 0.925 0.075
H11.2 Conjunctival scars
0.000 0.927 0.073
H49.2 Sixth [abducent] nerve palsy
0.000 0.928 0.072
H04.2 Epiphora
0.000 0.928 0.072
H54 Blindness and low vision
0.000 0.928 0.072
H42.8 Glaucoma in other diseases classified elsewhere
0.000 0.928 0.071
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.000 0.928 0.071
H31.4 Choroidal detachment
0.000 0.930 0.070
H31.2 Hereditary choroidal dystrophy
0.000 0.930 0.070
H54.9 Unspecified visual impairment (binocular)
0.000 0.931 0.069
H00.0 Hordeolum and other deep inflammation of eyelid
0.000 0.932 0.068
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.933 0.067
H33.1 Retinoschisis and retinal cysts
0.000 0.933 0.067
H33.4 Traction detachment of retina
0.000 0.934 0.066
H31.9 Disorder of choroid, unspecified
0.000 0.934 0.066
H43 Disorders of vitreous body
0.000 0.934 0.066
H34 Retinal vascular occlusions
0.000 0.938 0.062
C78.4 Secondary malignant neoplasm of small intestine
0.061 0.938 0.000
H11.8 Other specified disorders of conjunctiva
0.000 0.939 0.061
H11.0 Pterygium
0.000 0.939 0.061
H25.0 Senile incipient cataract
0.000 0.939 0.061
H54.2 Low vision, both eyes
0.000 0.940 0.060
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.941 0.059
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.941 0.059
H31.0 Chorioretinal scars
0.000 0.942 0.057
H30.8 Other chorioretinal inflammations
0.000 0.943 0.057
H30.2 Posterior cyclitis
0.000 0.943 0.057
H30.1 Disseminated chorioretinal inflammation
0.000 0.943 0.057
H30.0 Focal chorioretinal inflammation
0.000 0.943 0.057
H11.3 Conjunctival haemorrhage
0.000 0.943 0.057
H31.3 Choroidal haemorrhage and rupture
0.000 0.944 0.056
H54.0 Blindness, both eyes
0.000 0.944 0.056
H10.8 Other conjunctivitis
0.000 0.944 0.055
H10.5 Blepharoconjunctivitis
0.000 0.944 0.055
H10.3 Acute conjunctivitis, unspecified
0.000 0.944 0.055
H10.2 Other acute conjunctivitis
0.000 0.944 0.055
H10.1 Acute atopic conjunctivitis
0.000 0.944 0.055
H10.0 Mucopurulent conjunctivitis
0.000 0.944 0.055
H30.9 Chorioretinal inflammation, unspecified
0.000 0.945 0.055
H10.4 Chronic conjunctivitis
0.000 0.945 0.054
H58.8 Visual disturbances in diseases classified elsewhere
0.000 0.946 0.054
H43.1 Vitreous haemorrhage
0.000 0.947 0.053
H05 Disorders of orbit
0.000 0.947 0.052
H36 Retinal disorders in diseases classified elsewhere
0.000 0.947 0.053
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.052 0.948 0.000
H57.0 Anomalies of pupillary function
0.000 0.948 0.052
H01 Other inflammation of eyelid
0.000 0.949 0.051
H54.5 Low vision, one eye
0.000 0.950 0.050
H57.8 Other specified disorders of eye and adnexa
0.000 0.951 0.049
H43.0 Vitreous prolapse
0.000 0.952 0.048
K43.9 Ventral hernia without obstruction or gangrene
0.048 0.952 0.000
H54.6 Unqualified visual loss, one eye
0.000 0.955 0.045
H57.9 Disorder of eye and adnexa, unspecified
0.000 0.955 0.045
H34.0 Transient retinal artery occlusion
0.000 0.955 0.045
H43.2 Crystalline deposits in vitreous body
0.000 0.955 0.045
H33.3 Retinal breaks without detachment
0.000 0.955 0.045
H54.3 Unqualified visual loss, both eyes
0.000 0.956 0.044
H34.8 Other retinal vascular occlusions
0.000 0.956 0.044
H34.1 Central retinal artery occlusion
0.000 0.957 0.043
H43.9 Disorder of vitreous body, unspecified
0.000 0.958 0.042
H34.9 Retinal vascular occlusion, unspecified
0.000 0.959 0.041
H25.9 Senile cataract, unspecified
0.000 0.961 0.039
H05.0 Acute inflammation of orbit
0.000 0.962 0.038
H11.4 Other conjunctival vascular disorders and cysts
0.000 0.962 0.038
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.962 0.038
H05.4 Enophthalmos
0.000 0.962 0.038
H05.3 Deformity of orbit
0.000 0.962 0.038
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.962 0.038
H05.1 Chronic inflammatory disorders of orbit
0.000 0.963 0.037
H01.1 Non-infectious dermatoses of eyelid
0.000 0.964 0.036
H54.1 Blindness, one eye, low vision, other eye
0.000 0.964 0.036
H01.9 Inflammation of eyelid, unspecified
0.000 0.964 0.036
H34.2 Other retinal artery occlusions
0.000 0.964 0.036
H54.4 Blindness, one eye
0.000 0.965 0.035
H43.3 Other vitreous opacities
0.000 0.966 0.034
H33.5 Other retinal detachments
0.000 0.967 0.033
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.032 0.968 0.000
H05.2 Exophthalmic conditions
0.000 0.969 0.031
C71 Malignant neoplasm of brain
0.030 0.970 0.000
C71.9 Brain, unspecified
0.029 0.971 0.000
H05.9 Disorder of orbit, unspecified
0.000 0.972 0.028
C71.0 Cerebrum, except lobes and ventricles
0.027 0.973 0.000
C71.3 Parietal lobe
0.027 0.973 0.000
C71.8 Overlapping lesion of brain
0.026 0.974 0.000
H05.8 Other disorders of orbit
0.000 0.974 0.026
H10.9 Conjunctivitis, unspecified
0.000 0.974 0.026
H40 Glaucoma
0.000 0.974 0.026
H57.1 Ocular pain
0.000 0.974 0.025
H50 Other strabismus
0.000 0.975 0.025
H54.7 Unspecified visual loss
0.000 0.976 0.024
C71.1 Frontal lobe
0.023 0.977 0.000
H40.5 Glaucoma secondary to other eye disorders
0.000 0.977 0.023
C71.7 Brain stem
0.023 0.977 0.000
H40.4 Glaucoma secondary to eye inflammation
0.000 0.978 0.022
H01.8 Other specified inflammation of eyelid
0.000 0.978 0.021
C71.6 Cerebellum
0.021 0.979 0.000
C71.5 Cerebral ventricle
0.021 0.979 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.979 0.021
C71.2 Temporal lobe
0.021 0.979 0.000
H01.0 Blepharitis
0.000 0.980 0.020
C71.4 Occipital lobe
0.020 0.980 0.000
H50.4 Other and unspecified heterotropia
0.000 0.980 0.020
H40.6 Glaucoma secondary to drugs
0.000 0.981 0.019
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.981 0.019
H40.3 Glaucoma secondary to eye trauma
0.000 0.981 0.018
H40.0 Glaucoma suspect
0.000 0.982 0.018
H50.6 Mechanical strabismus
0.000 0.982 0.018
H50.3 Intermittent heterotropia
0.000 0.982 0.018
E16.2 Hypoglycaemia, unspecified
0.018 0.982 0.000
H50.5 Heterophoria
0.000 0.982 0.018
H50.8 Other specified strabismus
0.000 0.983 0.017
I20.8 Other forms of angina pectoris
0.016 0.984 0.000
E16 Other disorders of pancreatic internal secretion
0.016 0.984 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.985 0.015
K31.8 Other specified diseases of stomach and duodenum
0.015 0.985 0.000
H43.8 Other disorders of vitreous body
0.000 0.986 0.014
E16.0 Drug-induced hypoglycaemia without coma
0.014 0.986 0.000
E16.1 Other hypoglycaemia
0.014 0.986 0.000
D86.0 Sarcoidosis of lung
0.000 0.987 0.013
H50.0 Convergent concomitant strabismus
0.000 0.987 0.012
H02 Other disorders of eyelid
0.000 0.988 0.012
H50.2 Vertical strabismus
0.000 0.988 0.011
K43 Ventral hernia
0.011 0.988 0.000
H40.8 Other glaucoma
0.000 0.989 0.011
E16.9 Disorder of pancreatic internal secretion, unspecified
0.011 0.989 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.011 0.989 0.000
E16.4 Abnormal secretion of gastrin
0.011 0.989 0.000
E16.3 Increased secretion of glucagon
0.011 0.989 0.000
H50.9 Strabismus, unspecified
0.000 0.989 0.011
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.010 0.989 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.990 0.010
H02.0 Entropion and trichiasis of eyelid
0.000 0.991 0.009
H02.5 Other disorders affecting eyelid function
0.000 0.991 0.009
H02.2 Lagophthalmos
0.000 0.991 0.009
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.991 0.009
H00.1 Chalazion
0.000 0.991 0.009
H02.6 Xanthelasma of eyelid
0.000 0.991 0.009
H02.4 Ptosis of eyelid
0.000 0.991 0.009
K43.7 Other and unspecified ventral hernia with gangrene
0.008 0.991 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.008 0.991 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.008 0.991 0.000
K43.4 Parastomal hernia with gangrene
0.008 0.991 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.008 0.991 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.008 0.991 0.000
K43.1 Ventral hernia with gangrene
0.008 0.991 0.000
H40.2 Primary angle-closure glaucoma
0.000 0.992 0.008
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.992 0.008
H36.0 Diabetic retinopathy
0.000 0.992 0.008
H02.1 Ectropion of eyelid
0.000 0.992 0.008
C70 Malignant neoplasm of meninges
0.008 0.992 0.000
E83.5 Disorders of calcium metabolism
0.008 0.992 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.008 0.992 0.000
D86 Sarcoidosis
0.000 0.993 0.007
O14.0 Moderate preeclampsia
0.000 0.993 0.007
C69 Malignant neoplasm of eye and adnexa
0.007 0.993 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.007 0.993 0.000
D50.8 Other iron deficiency anaemias
0.007 0.993 0.000
C70.0 Cerebral meninges
0.006 0.994 0.000
C70.9 Meninges, unspecified
0.006 0.994 0.000
C70.1 Spinal meninges
0.006 0.994 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.994 0.006
H40.1 Primary open-angle glaucoma
0.000 0.994 0.006
I35.1 Aortic (valve) insufficiency
0.006 0.994 0.000
C72.9 Central nervous system, unspecified
0.006 0.994 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.006 0.994 0.000
C72.5 Other and unspecified cranial nerves
0.006 0.994 0.000
C72.4 Acoustic nerve
0.006 0.994 0.000
C72.3 Optic nerve
0.006 0.994 0.000
C72.2 Olfactory nerve
0.006 0.994 0.000
C72.1 Cauda equina
0.006 0.994 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.994 0.006
L03.1 Cellulitis of other parts of limb
0.000 0.994 0.006
C72.0 Spinal cord
0.005 0.994 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.995 0.005
C69.0 Conjunctiva
0.005 0.995 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.995 0.005
C69.6 Orbit
0.005 0.995 0.000
D86.3 Sarcoidosis of skin
0.000 0.995 0.005
S92.30 Fracture of metatarsal bone (closed)
0.000 0.995 0.005
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.005 0.995 0.000
C69.8 Overlapping lesion of eye and adnexa
0.005 0.995 0.000
C69.5 Lachrymal gland and duct
0.005 0.995 0.000
C69.4 Ciliary body
0.005 0.995 0.000
C69.2 Retina
0.005 0.995 0.000
C69.1 Cornea
0.005 0.995 0.000
Z32.1 Pregnancy confirmed
0.000 0.995 0.005
E15 Nondiabetic hypoglycaemic coma
0.005 0.995 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.005 0.995 0.000
I35.8 Other aortic valve disorders
0.005 0.995 0.000
H35 Other retinal disorders
0.000 0.995 0.005
T80 Complications following infusion, transfusion and therapeutic injection
0.005 0.995 0.000
S92.3 Fracture of metatarsal bone
0.000 0.995 0.005
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.005 0.995 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.000 0.995 0.005
H50.1 Divergent concomitant strabismus
0.000 0.995 0.004
S92.20 Fracture of other tarsal bone(s) (closed)
0.000 0.995 0.004
F81.9 Developmental disorder of scholastic skills, unspecified
0.000 0.995 0.004
O14.9 Preeclampsia, unspecified
0.000 0.996 0.004
S92.2 Fracture of other tarsal bone(s)
0.000 0.996 0.004
S92 Fracture of foot, except ankle
0.000 0.996 0.004
C69.9 Eye, unspecified
0.004 0.996 0.000
K59.0 Constipation
0.004 0.996 0.000
N18.2 Chronic kidney disease, stage 2
0.000 0.996 0.004
S92.5 Fracture of other toe
0.000 0.996 0.004
I70 Atherosclerosis
0.000 0.996 0.004
S92.50 Fracture of other toe (closed)
0.000 0.996 0.004
K43.0 Ventral hernia with obstruction, without gangrene
0.004 0.996 0.000
C69.3 Choroid
0.004 0.996 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.004 0.996 0.000
O14.1 Severe preeclampsia
0.000 0.996 0.004
I35 Nonrheumatic aortic valve disorders
0.004 0.996 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.000 0.996 0.004
H35.1 Retinopathy of prematurity
0.000 0.996 0.004
S92.7 Multiple fractures of foot
0.000 0.996 0.004
I35.9 Aortic valve disorder, unspecified
0.004 0.996 0.000
T80.6 Other serum reactions
0.003 0.996 0.000
T80.5 Anaphylactic shock due to serum
0.003 0.996 0.000
T80.4 Rh incompatibility reaction
0.003 0.996 0.000
T80.3 ABO incompatibility reaction
0.003 0.996 0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection
0.003 0.996 0.000
S92.31 Fracture of metatarsal bone (open)
0.000 0.996 0.003
O14.2 HELLP syndrome
0.000 0.996 0.003
H74.3 Other acquired abnormalities of ear ossicles
0.003 0.997 0.000
S92.0 Fracture of calcaneus
0.000 0.997 0.003
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection
0.003 0.997 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.003 0.997 0.000
I49.8 Other specified cardiac arrhythmias
0.000 0.997 0.003
S92.4 Fracture of great toe
0.000 0.997 0.003
H35.4 Peripheral retinal degeneration
0.000 0.997 0.003
S92.21 Fracture of other tarsal bone(s) (open)
0.000 0.997 0.003
S92.9 Fracture of foot, unspecified
0.000 0.997 0.003
I70.1 Atherosclerosis of renal artery
0.000 0.997 0.003
I70.8 Atherosclerosis of other arteries
0.000 0.997 0.003
S92.51 Fracture of other toe (open)
0.000 0.997 0.003
H35.7 Separation of retinal layers
0.000 0.997 0.003
I70.9 Generalised and unspecified atherosclerosis
0.000 0.997 0.003
S92.70 Multiple fractures of foot (closed)
0.000 0.997 0.003
H35.0 Background retinopathy and retinal vascular changes
0.000 0.997 0.003
S92.1 Fracture of talus
0.000 0.997 0.003
H61.2 Impacted cerumen
0.000 0.997 0.003
H35.9 Retinal disorder, unspecified
0.000 0.997 0.003
I27.0 Primary pulmonary hypertension
0.000 0.997 0.003
K31.7 Polyp of stomach and duodenum
0.003 0.997 0.000
I70.0 Atherosclerosis of aorta
0.000 0.997 0.003
S92.71 Multiple fractures of foot (open)
0.000 0.997 0.003
O69.1 Labour and delivery complicated by cord around neck, with compression
0.003 0.997 0.000
S92.00 Fracture of calcaneus (closed)
0.000 0.997 0.003
S19.9 Unspecified injury of neck
0.003 0.997 0.000
S92.40 Fracture of great toe (closed)
0.000 0.997 0.003
S92.01 Fracture of calcaneus (open)
0.000 0.997 0.003
H35.6 Retinal haemorrhage
0.000 0.997 0.003
Q25 Congenital malformations of great arteries
0.003 0.997 0.000
S92.41 Fracture of great toe (open)
0.000 0.997 0.003
Q23.0 Congenital stenosis of aortic valve
0.003 0.997 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.997 0.003
S92.91 Fracture of foot, unspecified (open)
0.000 0.997 0.002
S92.90 Fracture of foot, unspecified (closed)
0.000 0.997 0.002
H35.5 Hereditary retinal dystrophy
0.000 0.997 0.003
Q25.4 Other congenital malformations of aorta
0.003 0.997 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.997 0.002
H74.0 Tympanosclerosis
0.003 0.997 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.997 0.002
S12.20 Fracture of other specified cervical vertebra (closed)
0.003 0.997 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.003 0.997 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.997 0.002
S06.30 Focal brain injury (without open intracranial wound)
0.003 0.997 0.000
Q23 Congenital malformations of aortic and mitral valves
0.003 0.997 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.997 0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.997 0.002
S92.11 Fracture of talus (open)
0.000 0.997 0.002
H74.1 Adhesive middle ear disease
0.002 0.997 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.002 0.997 0.000
H60.9 Otitis externa, unspecified
0.000 0.998 0.002
N95.3 States associated with artificial menopause
0.000 0.998 0.002
Q25.3 Stenosis of aorta
0.002 0.998 0.000
S19.8 Other specified injuries of neck
0.002 0.998 0.000
F81 Specific developmental disorders of scholastic skills
0.000 0.998 0.002
Q25.1 Coarctation of aorta
0.002 0.998 0.000
H74 Other disorders of middle ear and mastoid
0.002 0.998 0.000
Z32 Pregnancy examination and test
0.000 0.998 0.002
H35.2 Other proliferative retinopathy
0.000 0.998 0.002
Q20-Q28 Congenital malformations of the circulatory system
0.002 0.998 0.000
S19 Other and unspecified injuries of neck
0.002 0.998 0.000
Q27 Other congenital malformations of peripheral vascular system
0.002 0.998 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.002 0.998 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.998 0.002
Q27.8 Other specified congenital malformations of peripheral vascular system
0.002 0.998 0.000
H35.8 Other specified retinal disorders
0.000 0.998 0.002
Q22.1 Congenital pulmonary valve stenosis
0.002 0.998 0.000
S92.10 Fracture of talus (closed)
0.000 0.998 0.002
D39.1 Ovary
0.002 0.998 0.000
L05.0 Pilonidal cyst with abscess
0.000 0.998 0.002
Q25.9 Congenital malformation of great arteries, unspecified
0.002 0.998 0.000
Q25.8 Other congenital malformations of great arteries
0.002 0.998 0.000
Q25.5 Atresia of pulmonary artery
0.002 0.998 0.000
Q25.2 Atresia of aorta
0.002 0.998 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.000 0.998 0.002
H02.9 Disorder of eyelid, unspecified
0.000 0.998 0.002
J95.8 Other postprocedural respiratory disorders
0.002 0.998 0.000
C76.2 Abdomen
0.002 0.998 0.000
Q23.1 Congenital insufficiency of aortic valve
0.002 0.998 0.000
Q25.0 Patent ductus arteriosus
0.002 0.998 0.000
S12.2 Fracture of other specified cervical vertebra
0.002 0.998 0.000
C80 Malignant neoplasm without specification of site
0.002 0.998 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.002 0.998 0.000
C76.7 Other ill-defined sites
0.002 0.998 0.000
C76.5 Lower limb
0.002 0.998 0.000
C76.4 Upper limb
0.002 0.998 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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