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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1012899
log Bayes Factor = 33.977
Chromosome 6   position 25,605,091  (GRCh37) Explore rs1012899 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
D64.9 Anaemia, unspecified
0.788 0.212 0.000
D64 Other anaemias
0.702 0.298 0.000
K90 Intestinal malabsorption
0.622 0.378 0.000
D60-D64 Aplastic and other anaemias
0.595 0.405 0.000
D64.8 Other specified anaemias
0.586 0.414 0.000
D86.9 Sarcoidosis, unspecified
0.521 0.479 0.000
D86 Sarcoidosis
0.520 0.480 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.513 0.487 0.000
D80-D89 Certain disorders involving the immune mechanism
0.513 0.487 0.000
D64.4 Congenital dyserythropoietic anaemia
0.503 0.497 0.000
D64.3 Other sideroblastic anaemias
0.503 0.497 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.503 0.497 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.503 0.497 0.000
D64.0 Hereditary sideroblastic anaemia
0.503 0.497 0.000
D62 Acute posthaemorrhagic anaemia
0.496 0.504 0.000
K90.9 Intestinal malabsorption, unspecified
0.494 0.506 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.489 0.511 0.000
D55-D59 Haemolytic anaemias
0.477 0.523 0.000
D61 Other aplastic anaemias
0.473 0.527 0.000
D86.3 Sarcoidosis of skin
0.461 0.539 0.000
D59 Acquired haemolytic anaemia
0.447 0.553 0.000
K90.3 Pancreatic steatorrhoea
0.446 0.554 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.446 0.554 0.000
K90.1 Tropical sprue
0.446 0.554 0.000
K90.8 Other intestinal malabsorption
0.441 0.559 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.426 0.573 0.000
N20.0 Calculus of kidney
0.000 0.580 0.420
D86.0 Sarcoidosis of lung
0.419 0.581 0.000
D59.1 Other autoimmune haemolytic anaemias
0.410 0.590 0.000
N20 Calculus of kidney and ureter
0.000 0.609 0.391
D83 Common variable immunodeficiency
0.388 0.612 0.000
D61.9 Aplastic anaemia, unspecified
0.376 0.624 0.000
D58 Other hereditary haemolytic anaemias
0.374 0.626 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.373 0.627 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.373 0.627 0.000
D84 Other immunodeficiencies
0.372 0.628 0.000
D61.0 Constitutional aplastic anaemia
0.371 0.629 0.000
D86.8 Sarcoidosis of other and combined sites
0.369 0.631 0.000
D82 Immunodeficiency associated with other major defects
0.368 0.632 0.000
D81 Combined immunodeficiencies
0.368 0.632 0.000
N20.1 Calculus of ureter
0.000 0.638 0.362
N20.2 Calculus of kidney with calculus of ureter
0.000 0.651 0.349
D57 Sickle-cell disorders
0.342 0.657 0.000
D55 Anaemia due to enzyme disorders
0.342 0.657 0.000
D80 Immunodeficiency with predominantly antibody defects
0.341 0.659 0.000
D61.8 Other specified aplastic anaemias
0.339 0.661 0.000
D61.3 Idiopathic aplastic anaemia
0.339 0.661 0.000
D61.2 Aplastic anaemia due to other external agents
0.339 0.661 0.000
D86.1 Sarcoidosis of lymph nodes
0.335 0.665 0.000
D56 Thalassaemia
0.330 0.670 0.000
D59.8 Other acquired haemolytic anaemias
0.321 0.679 0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.321 0.679 0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.321 0.679 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.321 0.679 0.000
D59.3 Haemolytic-uraemic syndrome
0.321 0.679 0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.321 0.679 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.321 0.679 0.000
N20.9 Urinary calculus, unspecified
0.000 0.682 0.318
D61.1 Drug-induced aplastic anaemia
0.316 0.684 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.306 0.694 0.000
D60.8 Other acquired pure red cell aplasias
0.306 0.694 0.000
D60.1 Transient acquired pure red cell aplasia
0.306 0.694 0.000
D60.0 Chronic acquired pure red cell aplasia
0.306 0.694 0.000
D83.9 Common variable immunodeficiency, unspecified
0.298 0.702 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.293 0.707 0.000
D58.2 Other haemoglobinopathies
0.290 0.710 0.000
D84.1 Defects in the complement system
0.279 0.721 0.000
D83.8 Other common variable immunodeficiencies
0.278 0.722 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.278 0.722 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.278 0.722 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.278 0.722 0.000
D84.8 Other specified immunodeficiencies
0.274 0.726 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.268 0.732 0.000
D58.1 Hereditary elliptocytosis
0.268 0.732 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.267 0.733 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.266 0.734 0.000
D81.9 Combined immunodeficiency, unspecified
0.264 0.736 0.000
D81.8 Other combined immunodeficiencies
0.264 0.736 0.000
D81.7 Major histocompatibility complex class II deficiency
0.264 0.736 0.000
D81.6 Major histocompatibility complex class I deficiency
0.264 0.736 0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.264 0.736 0.000
D81.4 Nezelof's syndrome
0.264 0.736 0.000
D81.3 Adenosine deaminase [ADA] deficiency
0.264 0.736 0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.264 0.736 0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.264 0.736 0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.264 0.736 0.000
D82.9 Immunodeficiency associated with major defect, unspecified
0.264 0.736 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.264 0.736 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.264 0.736 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.264 0.736 0.000
D82.2 Immunodeficiency with short-limbed stature
0.264 0.736 0.000
D82.1 Di George's syndrome
0.264 0.736 0.000
D82.0 Wiskott-Aldrich syndrome
0.264 0.736 0.000
D84.9 Immunodeficiency, unspecified
0.251 0.749 0.000
D58.0 Hereditary spherocytosis
0.250 0.750 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.249 0.751 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.246 0.754 0.000
D55.9 Anaemia due to enzyme disorder, unspecified
0.246 0.754 0.000
D55.8 Other anaemias due to enzyme disorders
0.246 0.754 0.000
D55.3 Anaemia due to disorders of nucleotide metabolism
0.246 0.754 0.000
D55.2 Anaemia due to disorders of glycolytic enzymes
0.246 0.754 0.000
D55.1 Anaemia due to other disorders of glutathione metabolism
0.246 0.754 0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.246 0.754 0.000
D57.8 Other sickle-cell disorders
0.246 0.754 0.000
D57.3 Sickle-cell trait
0.246 0.754 0.000
D57.2 Double heterozygous sickling disorders
0.246 0.754 0.000
D57.1 Sickle-cell anaemia without crisis
0.246 0.754 0.000
D57.0 Sickle-cell anaemia with crisis
0.246 0.754 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.245 0.754 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.244 0.755 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.244 0.755 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.244 0.755 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.244 0.755 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.244 0.755 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.244 0.755 0.000
D56.9 Thalassaemia, unspecified
0.237 0.763 0.000
D56.8 Other thalassaemias
0.237 0.763 0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.237 0.763 0.000
D56.2 Delta-beta thalassaemia
0.237 0.763 0.000
D56.0 Alpha thalassaemia
0.237 0.763 0.000
D56.1 Beta thalassaemia
0.231 0.769 0.000
D56.3 Thalassaemia trait
0.230 0.770 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.225 0.775 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.207 0.792 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.201 0.799 0.000
D50-D53 Nutritional anaemias
0.192 0.808 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.191 0.809 0.000
D89.3 Immune reconstitution syndrome
0.191 0.809 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.183 0.817 0.000
D89.1 Cryoglobulinaemia
0.171 0.829 0.000
D37.5 Rectum
0.000 0.830 0.170
D63.1 Anaemia in other chronic diseases classified elsewhere
0.161 0.839 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.000 0.840 0.160
D37.7 Other digestive organs
0.000 0.847 0.153
D37.1 Stomach
0.000 0.847 0.153
D37.6 Liver, gallbladder and bile ducts
0.000 0.855 0.145
K90-K93 Other diseases of the digestive system
0.144 0.856 0.000
D53 Other nutritional anaemias
0.143 0.857 0.000
D52 Folate deficiency anaemia
0.136 0.864 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.128 0.872 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.121 0.878 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.121 0.879 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.115 0.885 0.000
D37.2 Small intestine
0.000 0.890 0.109
D53.9 Nutritional anaemia, unspecified
0.107 0.893 0.000
D37.3 Appendix
0.000 0.894 0.106
D37.0 Lip, oral cavity and pharynx
0.000 0.896 0.104
K93 Disorders of other digestive organs in diseases classified elsewhere
0.104 0.896 0.000
D53.8 Other specified nutritional anaemias
0.102 0.897 0.000
D53.2 Scorbutic anaemia
0.102 0.897 0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.102 0.897 0.000
D53.0 Protein deficiency anaemia
0.102 0.897 0.000
D37.9 Digestive organ, unspecified
0.000 0.898 0.102
K91.4 Colostomy and enterostomy malfunction
0.099 0.901 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.000 0.902 0.098
D52.8 Other folate deficiency anaemias
0.098 0.902 0.000
D52.1 Drug-induced folate deficiency anaemia
0.098 0.902 0.000
D52.0 Dietary folate deficiency anaemia
0.098 0.902 0.000
D52.9 Folate deficiency anaemia, unspecified
0.096 0.903 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.095 0.905 0.000
D51 Vitamin B12 deficiency anaemia
0.095 0.905 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.091 0.909 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.090 0.910 0.000
D67 Hereditary factor IX deficiency
0.087 0.913 0.000
K91.3 Postoperative intestinal obstruction
0.086 0.914 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.083 0.917 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.083 0.917 0.000
K91.1 Postgastric surgery syndromes
0.081 0.919 0.000
N20-N23 Urolithiasis
0.000 0.920 0.080
K91.5 Postcholecystectomy syndrome
0.077 0.923 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.077 0.923 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.077 0.923 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.074 0.925 0.000
K93.1 Megacolon in Chagas' disease
0.074 0.925 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.074 0.925 0.000
D66 Hereditary factor VIII deficiency
0.074 0.926 0.000
C43 Malignant melanoma of skin
0.072 0.928 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.068 0.931 0.000
D51.2 Transcobalamin II deficiency
0.068 0.931 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.068 0.931 0.000
C43.9 Malignant melanoma of skin, unspecified
0.066 0.934 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.065 0.935 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.062 0.938 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.062 0.938 0.000
D74 Methaemoglobinaemia
0.060 0.940 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.060 0.940 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.060 0.940 0.000
C85.1 B-cell lymphoma, unspecified
0.060 0.940 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.060 0.940 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.059 0.941 0.000
C43.5 Malignant melanoma of trunk
0.058 0.942 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.000 0.943 0.057
R79 Other abnormal findings of blood chemistry
0.000 0.943 0.057
D70 Agranulocytosis
0.057 0.943 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.057 0.943 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.056 0.944 0.000
N21 Calculus of lower urinary tract
0.000 0.944 0.056
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.055 0.944 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.055 0.945 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.054 0.946 0.000
E83 Disorders of mineral metabolism
0.000 0.947 0.053
D50 Iron deficiency anaemia
0.053 0.947 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.052 0.948 0.000
C82.2 Large cell, follicular
0.052 0.948 0.000
C43.8 Overlapping malignant melanoma of skin
0.052 0.948 0.000
C43.0 Malignant melanoma of lip
0.052 0.948 0.000
D63.0 Anaemia in neoplastic disease
0.050 0.949 0.000
N21.0 Calculus in bladder
0.000 0.950 0.050
C82.0 Small cleaved cell, follicular
0.050 0.950 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.000 0.952 0.048
C83 Diffuse non-Hodgkin's lymphoma
0.047 0.953 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.047 0.953 0.000
C43.4 Malignant melanoma of scalp and neck
0.046 0.954 0.000
D37.4 Colon
0.000 0.955 0.045
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.045 0.955 0.000
C92 Myeloid leukaemia
0.045 0.955 0.000
C95 Leukaemia of unspecified cell type
0.045 0.955 0.000
D73 Diseases of spleen
0.044 0.956 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.044 0.956 0.000
D74.9 Methaemoglobinaemia, unspecified
0.043 0.957 0.000
D74.8 Other methaemoglobinaemias
0.043 0.957 0.000
D74.0 Congenital methaemoglobinaemia
0.043 0.957 0.000
C85.0 Lymphosarcoma
0.043 0.957 0.000
C83.3 Large cell (diffuse)
0.043 0.957 0.000
C82.6 Cutaneous follicle centre lymphoma
0.043 0.957 0.000
C82.5 Diffuse follicle centre lymphoma
0.043 0.957 0.000
C82.4 Follicular lymphoma grade IIIb
0.043 0.957 0.000
D50.1 Sideropenic dysphagia
0.043 0.957 0.000
C92.0 Acute myeloid leukaemia
0.043 0.957 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.042 0.958 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.042 0.958 0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere
0.000 0.959 0.041
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]
0.000 0.959 0.041
R79.0 Abnormal level of blood mineral
0.000 0.959 0.041
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.040 0.959 0.000
C94 Other leukaemias of specified cell type
0.040 0.959 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.000 0.960 0.040
D76.2 Haemophagocytic syndrome, infection-associated
0.040 0.960 0.000
D76.1 Haemophagocytic lymphohistiocytosis
0.040 0.960 0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.040 0.960 0.000
C83.0 Small cell (diffuse)
0.040 0.960 0.000
C81 Hodgkin's disease
0.040 0.960 0.000
C86 Other specified types of T/NK-cell lymphoma
0.039 0.960 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.039 0.961 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.962 0.038
E83.8 Other disorders of mineral metabolism
0.000 0.962 0.038
E83.2 Disorders of zinc metabolism
0.000 0.962 0.038
E83.0 Disorders of copper metabolism
0.000 0.962 0.038
C93 Monocytic leukaemia
0.038 0.962 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.038 0.962 0.000
C95.9 Leukaemia, unspecified
0.036 0.964 0.000
C91 Lymphoid leukaemia
0.036 0.964 0.000
D76.3 Other histiocytosis syndromes
0.035 0.964 0.000
C84.5 Other and unspecified T-cell lymphomas
0.035 0.964 0.000
D69 Purpura and other haemorrhagic conditions
0.035 0.965 0.000
D72 Other disorders of white blood cells
0.034 0.966 0.000
D73.5 Infarction of spleen
0.034 0.966 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.034 0.966 0.000
C83.6 Undifferentiated (diffuse)
0.034 0.966 0.000
C83.5 Lymphoblastic (diffuse)
0.034 0.966 0.000
C83.4 Immunoblastic (diffuse)
0.034 0.966 0.000
C83.2 Mixed small and large cell (diffuse)
0.034 0.966 0.000
N21.1 Calculus in urethra
0.000 0.966 0.034
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.034 0.966 0.000
D73.4 Cyst of spleen
0.034 0.966 0.000
C82.3 Follicular lymphoma grade IIIa
0.033 0.966 0.000
C91.0 Acute lymphoblastic leukaemia
0.033 0.966 0.000
C92.9 Myeloid leukaemia, unspecified
0.033 0.967 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.032 0.968 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.032 0.968 0.000
C92.5 Acute myelomonocytic leukaemia
0.032 0.968 0.000
C92.3 Myeloid sarcoma
0.032 0.968 0.000
C92.2 Subacute myeloid leukaemia
0.032 0.968 0.000
C88 Malignant immunoproliferative diseases
0.032 0.968 0.000
C95.7 Other leukaemia of unspecified cell type
0.032 0.968 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.032 0.968 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.032 0.968 0.000
C95.0 Acute leukaemia of unspecified cell type
0.032 0.968 0.000
C83.1 Small cleaved cell (diffuse)
0.032 0.968 0.000
D73.9 Disease of spleen, unspecified
0.032 0.968 0.000
D73.3 Abscess of spleen
0.032 0.968 0.000
D73.2 Chronic congestive splenomegaly
0.032 0.968 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.031 0.968 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.031 0.968 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.031 0.968 0.000
C84.3 Lymphoepithelioid lymphoma
0.031 0.968 0.000
C84.2 T-zone lymphoma
0.031 0.968 0.000
C84.1 Sezary's diease
0.031 0.968 0.000
D68 Other coagulation defects
0.031 0.968 0.001
C81.2 Mixed cellularity
0.031 0.969 0.000
C81.0 Lymphocytic predominance
0.031 0.969 0.000
D73.1 Hypersplenism
0.030 0.969 0.000
C92.4 Acute promyelocytic leukaemia
0.030 0.970 0.000
C84.0 Mycosis fungoides
0.030 0.970 0.000
D73.8 Other diseases of spleen
0.030 0.970 0.000
C83.7 Burkitt's tumour
0.029 0.970 0.000
C94.7 Other specified leukaemias
0.029 0.971 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.029 0.971 0.000
C94.5 Acute myelofibrosis
0.029 0.971 0.000
C94.4 Acute panmyelosis
0.029 0.971 0.000
C94.3 Mast cell leukaemia
0.029 0.971 0.000
C94.2 Acute megakaryoblastic leukaemia
0.029 0.971 0.000
C94.1 Chronic erythraemia
0.029 0.971 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.029 0.971 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.029 0.971 0.000
C96.8 Histiocytic sarcoma
0.029 0.971 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.029 0.971 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.029 0.971 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.029 0.971 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.029 0.971 0.000
C96.3 True histiocytic lymphoma
0.029 0.971 0.000
C96.2 Malignant mast cell tumour
0.029 0.971 0.000
C96.1 Malignant histiocytosis
0.029 0.971 0.000
C96.0 Letterer-Siwe disease
0.029 0.971 0.000
D69.0 Allergic purpura
0.029 0.971 0.000
C81.7 Other Hodgkin's disease
0.029 0.971 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.971 0.029
C92.7 Other myeloid leukaemia
0.029 0.971 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.971 0.029
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.028 0.971 0.000
C81.3 Lymphocytic depletion
0.028 0.971 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.028 0.971 0.000
C86.4 Blastic NK-cell lymphoma
0.028 0.971 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.028 0.971 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.028 0.971 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.028 0.971 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.028 0.971 0.000
C91.5 Adult T-cell leukaemia
0.028 0.972 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.028 0.972 0.000
C93.9 Monocytic leukaemia, unspecified
0.027 0.972 0.000
C93.7 Other monocytic leukaemia
0.027 0.972 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.027 0.972 0.000
C93.2 Subacute monocytic leukaemia
0.027 0.972 0.000
C93.0 Acute monocytic leukaemia
0.027 0.972 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.027 0.972 0.000
D68.8 Other specified coagulation defects
0.026 0.973 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.026 0.974 0.000
C91.7 Other lymphoid leukaemia
0.026 0.974 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.026 0.974 0.000
C91.3 Prolymphocytic leukaemia
0.026 0.974 0.000
C91.2 Subacute lymphocytic leukaemia
0.026 0.974 0.000
D69.4 Other primary thrombocytopenia
0.026 0.974 0.000
D69.2 Other nonthrombocytopenic purpura
0.026 0.974 0.000
C81.1 Nodular sclerosis
0.026 0.974 0.000
C91.9 Lymphoid leukaemia, unspecified
0.026 0.974 0.000
D68.1 Hereditary factor XI deficiency
0.026 0.974 0.000
D69.8 Other specified haemorrhagic conditions
0.026 0.974 0.000
D69.1 Qualitative platelet defects
0.026 0.974 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.025 0.975 0.000
C93.1 Chronic monocytic leukaemia
0.025 0.975 0.000
D72.9 Disorder of white blood cells, unspecified
0.025 0.975 0.000
D72.0 Genetic anomalies of leukocytes
0.025 0.975 0.000
N21.8 Other lower urinary tract calculus
0.001 0.975 0.024
C81.9 Hodgkin's disease, unspecified
0.024 0.976 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.023 0.977 0.000
C88.7 Other malignant immunoproliferative diseases
0.023 0.977 0.000
C88.3 Immunoproliferative small intestinal disease
0.023 0.977 0.000
C88.2 Gamma heavy chain disease
0.023 0.977 0.000
C88.1 Alpha heavy chain disease
0.023 0.977 0.000
D69.9 Haemorrhagic condition, unspecified
0.023 0.977 0.000
D68.4 Acquired coagulation factor deficiency
0.022 0.977 0.001
D68.6 Other Thrombophilia
0.021 0.979 0.001
D72.1 Eosinophilia
0.020 0.979 0.000
C90.1 Plasma cell leukaemia
0.020 0.979 0.000
C84.4 Peripheral T-cell lymphoma
0.020 0.980 0.000
N23 Unspecified renal colic
0.000 0.980 0.020
D68.9 Coagulation defect, unspecified
0.020 0.980 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.020 0.980 0.000
C90.3 Solitary plasmacytoma
0.020 0.980 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.020 0.980 0.000
C92.1 Chronic myeloid leukaemia
0.019 0.980 0.000
C91.4 Hairy-cell leukaemia
0.019 0.981 0.000
M34.9 Systemic sclerosis, unspecified
0.019 0.981 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.981 0.019
D50.9 Iron deficiency anaemia, unspecified
0.018 0.982 0.000
C90.2 Plasmacytoma, extramedullary
0.018 0.982 0.000
T42.4 Benzodiazepines
0.000 0.982 0.018
D68.5 Primary Thrombophilia
0.017 0.982 0.001
D75 Other diseases of blood and blood-forming organs
0.017 0.983 0.000
D68.0 Von Willebrand's disease
0.017 0.983 0.001
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.016 0.983 0.001
M34 Systemic sclerosis
0.017 0.983 0.000
M34.1 CR(E)ST syndrome
0.016 0.984 0.000
D69.5 Secondary thrombocytopenia
0.016 0.984 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.985 0.015
D69.6 Thrombocytopenia, unspecified
0.015 0.985 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.985 0.015
D69.3 Idiopathic thrombocytopenic purpura
0.014 0.985 0.000
C90.0 Multiple myeloma
0.014 0.986 0.000
M34.8 Other forms of systemic sclerosis
0.014 0.986 0.000
T39.0 Salicylates
0.000 0.987 0.013
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.987 0.013
D75.0 Familial erythrocytosis
0.012 0.987 0.000
D73.0 Hyposplenism
0.012 0.987 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.012 0.988 0.000
M34.0 Progressive systemic sclerosis
0.012 0.988 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.012 0.988 0.000
H65 Nonsuppurative otitis media
0.000 0.988 0.012
M24 Other specific joint derangements
0.012 0.988 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.988 0.012
H65.2 Chronic serous otitis media
0.000 0.988 0.012
D75.9 Disease of blood and blood-forming organs, unspecified
0.011 0.988 0.000
M24.5 Contracture of joint
0.011 0.989 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.989 0.011
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.989 0.011
M24.8 Other specific joint derangements, not elsewhere classified
0.011 0.989 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.989 0.011
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.989 0.011
T42.3 Barbiturates
0.000 0.989 0.011
T42.2 Succinimides and oxazolidinediones
0.000 0.989 0.011
M24.0 Loose body in joint
0.011 0.989 0.000
T42.1 Iminostilbenes
0.000 0.989 0.011
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.989 0.011
M24.54 Contracture of joint (Hand)
0.010 0.990 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.990 0.010
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.990 0.010
M24.4 Recurrent dislocation and subluxation of joint
0.010 0.990 0.000
D72.8 Other specified disorders of white blood cells
0.010 0.990 0.000
D75.2 Essential thrombocytosis
0.010 0.990 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.010 0.990 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.990 0.010
M24.1 Other articular cartilage disorders
0.010 0.990 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.990 0.010
M24.01 Loose body in joint (Shoulder region)
0.010 0.990 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.990 0.009
M24.52 Contracture of joint (Upper arm)
0.009 0.991 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.009 0.991 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.009 0.991 0.000
H65.4 Other chronic nonsuppurative otitis media
0.000 0.991 0.009
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.009 0.991 0.000
M24.7 Protrusio acetabuli
0.009 0.991 0.000
T42.0 Hydantoin derivatives
0.000 0.991 0.009
K92 Other diseases of digestive system
0.009 0.991 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.009 0.991 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.009 0.991 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.009 0.991 0.000
M24.6 Ankylosis of joint
0.009 0.991 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.009 0.991 0.000
M24.02 Loose body in joint (Upper arm)
0.009 0.991 0.000
M24.9 Joint derangement, unspecified
0.009 0.991 0.000
T39.4 Antirheumatics, not elsewhere classified
0.000 0.991 0.009
T39.2 Pyrazolone derivatives
0.000 0.991 0.009
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.009 0.991 0.000
M24.51 Contracture of joint (Shoulder region)
0.008 0.991 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.991 0.008
H65.0 Acute serous otitis media
0.000 0.991 0.008
K92.8 Other specified diseases of digestive system
0.009 0.991 0.000
H65.1 Other acute nonsuppurative otitis media
0.000 0.991 0.008
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.008 0.991 0.000
M24.59 Contracture of joint (Site unspecified)
0.008 0.992 0.000
M24.58 Contracture of joint (Other)
0.008 0.992 0.000
M24.53 Contracture of joint (Forearm)
0.008 0.992 0.000
M24.50 Contracture of joint (Multiple sites)
0.008 0.992 0.000
T39.1 4-Aminophenol derivatives
0.000 0.992 0.008
M24.56 Contracture of joint (Lower leg)
0.008 0.992 0.000
T36 Poisoning by systemic antibiotics
0.000 0.992 0.008
M24.04 Loose body in joint (Hand)
0.008 0.992 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.008 0.992 0.000
M24.57 Contracture of joint (Ankle and foot)
0.008 0.992 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.992 0.008
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.992 0.008
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.992 0.008
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.008 0.992 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.008 0.992 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.008 0.992 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.992 0.008
M24.09 Loose body in joint (Site unspecified)
0.008 0.992 0.000
M24.08 Loose body in joint (Other)
0.008 0.992 0.000
M24.06 Loose body in joint-Lower leg
0.008 0.992 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.008 0.992 0.000
M24.00 Loose body in joint (Multiple sites)
0.008 0.992 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.992 0.008
M24.03 Loose body in joint (Forearm)
0.008 0.992 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.992 0.008
L72.1 Trichilemmal cyst
0.000 0.992 0.008
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.992 0.008
M24.64 Ankylosis of joint (Hand)
0.008 0.992 0.000
T50.8 Diagnostic agents
0.000 0.992 0.008
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.992 0.007
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.992 0.007
T47.7 Emetics
0.000 0.992 0.007
T47.6 Antidiarrhoeal drugs
0.000 0.992 0.007
T47.5 Digestants
0.000 0.992 0.007
T47.4 Other laxatives
0.000 0.992 0.007
T47.3 Saline and osmotic laxatives
0.000 0.992 0.007
T47.2 Stimulant laxatives
0.000 0.992 0.007
T47.0 Histamine H(2)-receptor antagonists
0.000 0.992 0.007
T50.7 Analeptics and opioid receptor antagonists
0.000 0.992 0.007
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.992 0.007
T50.5 Appetite depressants
0.000 0.992 0.007
T50.4 Drugs affecting uric acid metabolism
0.000 0.992 0.007
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.992 0.007
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.992 0.007
T50.1 Loop [high-ceiling] diuretics
0.000 0.992 0.007
T50.0 Mineralocorticoids and their antagonists
0.000 0.992 0.007
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.007 0.993 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.007 0.993 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.007 0.993 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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