TreeWAS – Variant ID: rs10156309

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K02.9 Dental caries, unspecified	0.000	0.707	0.293
K02 Dental caries	0.000	0.796	0.204
K02.8 Other dental caries	0.000	0.849	0.150
K02.5 Caries with pulp exposure	0.000	0.854	0.146
K02.4 Odontoclasia	0.000	0.854	0.146
K02.3 Arrested dental caries	0.000	0.854	0.146
K02.2 Caries of cementum	0.000	0.854	0.146
K02.1 Caries of dentin	0.000	0.854	0.146
K02.0 Caries limited to enamel	0.000	0.854	0.146
K14.8 Other diseases of tongue	0.000	0.864	0.136
K14 Diseases of tongue	0.000	0.865	0.135
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.000	0.866	0.134
K12 Stomatitis and related lesions	0.000	0.872	0.128
K04 Diseases of pulp and periapical tissues	0.000	0.874	0.126
K04.5 Chronic apical periodontitis	0.000	0.881	0.119
K04.8 Radicular cyst	0.000	0.886	0.114
K04.6 Periapical abscess with sinus	0.000	0.890	0.110
K12.1 Other forms of stomatitis	0.000	0.890	0.110
K12.0 Recurrent oral aphthae	0.000	0.891	0.109
K14.0 Glossitis	0.000	0.892	0.108
K12.3 Oral mucositis (ulcerative)	0.000	0.894	0.106
K01 Embedded and impacted teeth	0.000	0.899	0.101
K09 Cysts of oral region, not elsewhere classified	0.000	0.899	0.101
K14.6 Glossodynia	0.000	0.903	0.097
K14.5 Plicated tongue	0.000	0.903	0.097
K14.4 Atrophy of tongue papillae	0.000	0.903	0.097
K14.3 Hypertrophy of tongue papillae	0.000	0.903	0.097
K14.2 Median rhomboid glossitis	0.000	0.903	0.097
K14.1 Geographic tongue	0.000	0.903	0.097
K03 Other diseases of hard tissues of teeth	0.000	0.903	0.096
K12.2 Cellulitis and abscess of mouth	0.000	0.906	0.094
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.907	0.093
K04.3 Abnormal hard tissue formation in pulp	0.000	0.909	0.091
K04.2 Pulp degeneration	0.000	0.909	0.091
K04.1 Necrosis of pulp	0.000	0.909	0.091
K14.9 Disease of tongue, unspecified	0.000	0.911	0.089
K10 Other diseases of jaws	0.000	0.911	0.089
K07 Dentofacial anomalies [including malocclusion]	0.000	0.912	0.088
K01.0 Embedded teeth	0.000	0.920	0.080
K09.2 Other cysts of jaw	0.000	0.922	0.078
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.924	0.076
K00 Disorders of tooth development and eruption	0.000	0.926	0.074
K09.9 Cyst of oral region, unspecified	0.000	0.928	0.072
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.928	0.072
K04.0 Pulpitis	0.000	0.928	0.072
K07.3 Anomalies of tooth position	0.000	0.929	0.071
K03.9 Disease of hard tissues of teeth, unspecified	0.000	0.930	0.069
K03.8 Other specified diseases of hard tissues of teeth	0.000	0.930	0.069
K03.7 Posteruptive colour changes of dental hard tissues	0.000	0.930	0.069
K03.6 Deposits [accretions] on teeth	0.000	0.930	0.069
K03.5 Ankylosis of teeth	0.000	0.930	0.069
K03.4 Hypercementosis	0.000	0.930	0.069
K03.3 Pathological resorption of teeth	0.000	0.930	0.069
K03.2 Erosion of teeth	0.000	0.930	0.069
K03.1 Abrasion of teeth	0.000	0.930	0.069
K03.0 Excessive attrition of teeth	0.000	0.930	0.069
K01.1 Impacted teeth	0.000	0.931	0.069
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.932	0.068
K09.0 Developmental odontogenic cysts	0.000	0.934	0.066
K10.9 Disease of jaws, unspecified	0.000	0.936	0.064
K10.3 Alveolitis of jaws	0.000	0.936	0.064
K10.1 Giant cell granuloma, central	0.000	0.936	0.064
K10.0 Developmental disorders of jaws	0.000	0.936	0.064
K07.9 Dentofacial anomaly, unspecified	0.000	0.937	0.063
K07.8 Other dentofacial anomalies	0.000	0.937	0.063
K07.5 Dentofacial functional abnormalities	0.000	0.937	0.063
K07.4 Malocclusion, unspecified	0.000	0.937	0.063
K07.2 Anomalies of dental arch relationship	0.000	0.937	0.063
K07.0 Major anomalies of jaw size	0.000	0.937	0.063
K10.8 Other specified diseases of jaws	0.000	0.937	0.063
K08 Other disorders of teeth and supporting structures	0.000	0.942	0.058
K06 Other disorders of gingiva and edentulous alveolar ridge	0.000	0.942	0.057
K10.2 Inflammatory conditions of jaws	0.000	0.943	0.056
K07.6 Temporomandibular joint disorders	0.000	0.946	0.053
K00.9 Disorder of tooth development, unspecified	0.000	0.947	0.053
K00.8 Other disorders of tooth development	0.000	0.947	0.053
K00.7 Teething syndrome	0.000	0.947	0.053
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.000	0.947	0.053
K00.4 Disturbances in tooth formation	0.000	0.947	0.053
K00.3 Mottled teeth	0.000	0.947	0.053
K00.2 Abnormalities of size and form of teeth	0.000	0.947	0.053
K00.1 Supernumerary teeth	0.000	0.947	0.053
K07.1 Anomalies of jaw-cranial base relationship	0.000	0.947	0.053
K04.7 Periapical abscess without sinus	0.000	0.949	0.050
K05 Gingivitis and periodontal diseases	0.000	0.950	0.049
K00.0 Anodontia	0.000	0.952	0.047
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.957	0.043
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.957	0.042
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.958	0.042
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.000	0.958	0.041
K06.0 Gingival recession	0.000	0.958	0.041
K00.6 Disturbances in tooth eruption	0.000	0.960	0.039
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.960	0.040
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.001	0.962	0.038
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.963	0.037
K05.2 Acute periodontitis	0.000	0.964	0.036
K05.5 Other periodontal diseases	0.000	0.964	0.036
K05.4 Periodontosis	0.000	0.964	0.036
K05.0 Acute gingivitis	0.000	0.964	0.036
K06.1 Gingival enlargement	0.001	0.966	0.033
K11 Diseases of salivary glands	0.000	0.970	0.030
K05.6 Periodontal disease, unspecified	0.000	0.972	0.028
K05.1 Chronic gingivitis	0.000	0.972	0.027
K13 Other diseases of lip and oral mucosa	0.000	0.973	0.027
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.001	0.974	0.026
K05.22 Aggressive periodontitis, generalized	0.000	0.974	0.026
K05.3 Chronic periodontitis	0.000	0.975	0.025
D13.1 Stomach	0.024	0.976	0.000
K11.7 Disturbances of salivary secretion	0.000	0.978	0.021
K11.4 Fistula of salivary gland	0.000	0.978	0.021
K11.3 Abscess of salivary gland	0.000	0.978	0.021
K11.0 Atrophy of salivary gland	0.000	0.978	0.021
K11.8 Other diseases of salivary glands	0.000	0.980	0.020
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.000	0.980	0.019
K13.5 Oral submucous fibrosis	0.000	0.980	0.019
K13.3 Hairy leukoplakia	0.000	0.980	0.019
K13.1 Cheek and lip biting	0.000	0.980	0.019
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.019	0.981	0.000
K11.6 Mucocele of salivary gland	0.000	0.981	0.019
K11.1 Hypertrophy of salivary gland	0.000	0.982	0.018
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.982	0.018
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.000	0.982	0.018
D13.4 Liver	0.018	0.982	0.000
K11.9 Disease of salivary gland, unspecified	0.000	0.983	0.017
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.983	0.017
D75.1 Secondary polycythaemia	0.017	0.983	0.000
D13.5 Extrahepatic bile ducts	0.017	0.983	0.000
K11.5 Sialolithiasis	0.000	0.984	0.016
K08.3 Retained dental root	0.000	0.984	0.016
K11.2 Sialoadenitis	0.000	0.984	0.016
K13.29 Other disturbances of oral epithelium, including tongue	0.000	0.986	0.014
D13.9 Ill-defined sites within the digestive system	0.014	0.986	0.000
D13.7 Endocrine pancreas	0.014	0.986	0.000
D13.6 Pancreas	0.014	0.986	0.000
D13.3 Other and unspecified parts of small intestine	0.014	0.986	0.000
D13.0 Oesophagus	0.014	0.986	0.000
D13.2 Duodenum	0.014	0.986	0.000
N81.3 Complete uterovaginal prolapse	0.013	0.987	0.000
D75 Other diseases of blood and blood-forming organs	0.012	0.988	0.000
N81.1 Cystocele	0.012	0.988	0.000
N81.6 Rectocele	0.012	0.988	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.989	0.011
N81 Female genital prolapse	0.011	0.989	0.000
D75.2 Essential thrombocytosis	0.010	0.990	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.010	0.990	0.000
N81.5 Vaginal enterocele	0.010	0.990	0.000
D75.0 Familial erythrocytosis	0.009	0.991	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.009	0.991	0.000
N81.8 Other female genital prolapse	0.009	0.991	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.991	0.009
N81.0 Female urethrocele	0.008	0.991	0.000
N81.9 Female genital prolapse, unspecified	0.008	0.992	0.000
K13.0 Diseases of lips	0.000	0.993	0.007
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.993	0.007
Z50.0 Cardiac rehabilitation	0.007	0.993	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.007	0.993	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.993	0.006
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.993	0.006
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.993	0.006
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.993	0.006
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.994	0.006
I12.0 Hypertensive renal disease with renal failure	0.000	0.994	0.006
C85.1 B-cell lymphoma, unspecified	0.000	0.994	0.006
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.005	0.994	0.000
H65.3 Chronic mucoid otitis media	0.000	0.995	0.005
D70 Agranulocytosis	0.005	0.995	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.995	0.005
N32.9 Bladder disorder, unspecified	0.005	0.995	0.000
D74 Methaemoglobinaemia	0.005	0.995	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.005	0.995	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.005	0.995	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.995	0.005
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.005	0.995	0.000
D76.3 Other histiocytosis syndromes	0.005	0.995	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.995	0.005
D69 Purpura and other haemorrhagic conditions	0.005	0.995	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.995	0.005
I12 Hypertensive renal disease	0.000	0.995	0.005
H25.1 Senile nuclear cataract	0.000	0.995	0.005
H65 Nonsuppurative otitis media	0.000	0.995	0.005
D66 Hereditary factor VIII deficiency	0.004	0.995	0.000
Z50 Care involving use of rehabilitation procedures	0.005	0.995	0.000
D69.4 Other primary thrombocytopenia	0.004	0.996	0.000
D68 Other coagulation defects	0.004	0.996	0.000
N32.3 Diverticulum of bladder	0.004	0.996	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.996	0.004
D76.2 Haemophagocytic syndrome, infection-associated	0.004	0.996	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.004	0.996	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.004	0.996	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.004	0.996	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.004	0.996	0.000
D69.5 Secondary thrombocytopenia	0.004	0.996	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.004	0.996	0.000
D73 Diseases of spleen	0.004	0.996	0.000
Z50.1 Other physical therapy	0.004	0.996	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.996	0.004
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.996	0.004
D74.9 Methaemoglobinaemia, unspecified	0.004	0.996	0.000
D74.8 Other methaemoglobinaemias	0.004	0.996	0.000
D74.0 Congenital methaemoglobinaemia	0.004	0.996	0.000
D72 Other disorders of white blood cells	0.004	0.996	0.000
Z50.8 Care involving use of rehabilitation procedures	0.004	0.996	0.000
D68.8 Other specified coagulation defects	0.004	0.996	0.000
D67 Hereditary factor IX deficiency	0.004	0.996	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.004	0.996	0.000
D69.9 Haemorrhagic condition, unspecified	0.004	0.996	0.000
D69.8 Other specified haemorrhagic conditions	0.004	0.996	0.000
D69.2 Other nonthrombocytopenic purpura	0.004	0.996	0.000
D69.1 Qualitative platelet defects	0.004	0.996	0.000
D69.0 Allergic purpura	0.004	0.996	0.000
H65.2 Chronic serous otitis media	0.000	0.996	0.004
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.996	0.003
C85.0 Lymphosarcoma	0.000	0.996	0.003
D68.5 Primary Thrombophilia	0.004	0.996	0.000
D68.2 Hereditary deficiency of other clotting factors	0.004	0.996	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.996	0.003
H65.0 Acute serous otitis media	0.000	0.996	0.003
T81 Complications of procedures, not elsewhere classified	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.003	0.996	0.000
Z50.6 Orthoptic training	0.003	0.996	0.000
Z50.3 Drug rehabilitation	0.003	0.996	0.000
D68.4 Acquired coagulation factor deficiency	0.003	0.997	0.000
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.003	0.997	0.000
Z50.5 Speech therapy	0.003	0.997	0.000
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
N28.1 Cyst of kidney, acquired	0.003	0.997	0.000
C44.3 Skin of other and unspecified parts of face	0.003	0.997	0.000
T42.4 Benzodiazepines	0.000	0.997	0.003
T81.4 Infection following a procedure, not elsewhere classified	0.000	0.997	0.003
D68.6 Other Thrombophilia	0.003	0.997	0.000
D73.8 Other diseases of spleen	0.003	0.997	0.000
D60-D64 Aplastic and other anaemias	0.003	0.997	0.000
D55-D59 Haemolytic anaemias	0.003	0.997	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.997	0.003
D73.9 Disease of spleen, unspecified	0.003	0.997	0.000
D73.5 Infarction of spleen	0.003	0.997	0.000
D73.4 Cyst of spleen	0.003	0.997	0.000
D73.3 Abscess of spleen	0.003	0.997	0.000
D73.2 Chronic congestive splenomegaly	0.003	0.997	0.000
D73.1 Hypersplenism	0.003	0.997	0.000
T81.9 Unspecified complication of procedure	0.000	0.997	0.003
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.000	0.997	0.003
M25.77 Osteophyte (Ankle and foot)	0.003	0.997	0.000
D61 Other aplastic anaemias	0.003	0.997	0.000
D72.9 Disorder of white blood cells, unspecified	0.003	0.997	0.000
D72.0 Genetic anomalies of leukocytes	0.003	0.997	0.000
N32 Other disorders of bladder	0.003	0.997	0.000
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
D72.1 Eosinophilia	0.003	0.997	0.000
D58 Other hereditary haemolytic anaemias	0.003	0.997	0.000
D62 Acute posthaemorrhagic anaemia	0.003	0.997	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.000	0.997	0.003
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.000	0.997	0.003
T81.7 Vascular complications following a procedure, not elsewhere classified	0.000	0.997	0.003
D68.0 Von Willebrand's disease	0.002	0.997	0.000
Z50.2 Alcohol rehabilitation	0.003	0.997	0.000
D58.0 Hereditary spherocytosis	0.002	0.997	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.000	0.997	0.003
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.002	0.997	0.000
D57 Sickle-cell disorders	0.002	0.997	0.000
D56 Thalassaemia	0.002	0.997	0.000
D55 Anaemia due to enzyme disorders	0.002	0.997	0.000
N92.6 Irregular menstruation, unspecified	0.003	0.997	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.997	0.003
D63 Anaemia in chronic diseases classified elsewhere	0.002	0.997	0.000
N81.4 Uterovaginal prolapse, unspecified	0.002	0.997	0.000
D61.8 Other specified aplastic anaemias	0.002	0.997	0.000
D61.3 Idiopathic aplastic anaemia	0.002	0.997	0.000
D61.2 Aplastic anaemia due to other external agents	0.002	0.997	0.000
D61.1 Drug-induced aplastic anaemia	0.002	0.997	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.997	0.000
N32.4 Rupture of bladder, nontraumatic	0.002	0.998	0.000
N32.2 Vesical fistula, not elsewhere classified	0.002	0.998	0.000
Z01.8 Other specified special examinations	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.998	0.002
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.002	0.998	0.000
N32.0 Bladder-neck obstruction	0.002	0.998	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.002	0.998	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.998	0.002
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.998	0.000
D60.8 Other acquired pure red cell aplasias	0.002	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
D56.9 Thalassaemia, unspecified	0.002	0.998	0.000
D56.8 Other thalassaemias	0.002	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.998	0.000
D56.3 Thalassaemia trait	0.002	0.998	0.000
D56.2 Delta-beta thalassaemia	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.002	0.998	0.000
D56.0 Alpha thalassaemia	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
F52.2 Failure of genital response	0.002	0.998	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
D63.1 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.000	0.998	0.002
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.998	0.002
Z02.8 Other examinations for administrative purposes	0.000	0.998	0.002
H80.9 Otosclerosis, unspecified	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
D73.0 Hyposplenism	0.002	0.998	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.998	0.002
J34.3 Hypertrophy of nasal turbinates	0.002	0.998	0.000
H43.8 Other disorders of vitreous body	0.000	0.998	0.002
N32.1 Vesicointestinal fistula	0.002	0.998	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.998	0.002
D84 Other immunodeficiencies	0.002	0.998	0.000
S62.60 Fracture of other finger (closed)	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.998	0.002
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.998	0.002
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.998	0.002
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.998	0.002
D83 Common variable immunodeficiency	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
L90.0 Lichen sclerosus et atrophicus	0.000	0.998	0.002
O70.0 First degree perineal laceration during delivery	0.000	0.998	0.002
N60.4 Mammary duct ectasia	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.001	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.998	0.002
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
H25 Senile cataract	0.000	0.998	0.002
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
D64 Other anaemias	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
E87.6 Hypokalaemia	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.001	0.998	0.000
D84.1 Defects in the complement system	0.001	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.001	0.998	0.000
D81.8 Other combined immunodeficiencies	0.001	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.998	0.000
D81.4 Nezelof's syndrome	0.001	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.1 Di George's syndrome	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
D64.8 Other specified anaemias	0.001	0.998	0.000
H72 Perforation of tympanic membrane	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
M25.74 Osteophyte (Hand)	0.002	0.998	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000
D32.0 Cerebral meninges	0.002	0.998	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.002	0.998	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
H25.2 Senile cataract, morgagnian type	0.000	0.998	0.001
M25.83 Other specified joint disorders (Forearm)	0.001	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.998	0.000
D64.4 Congenital dyserythropoietic anaemia	0.001	0.998	0.000
D64.3 Other sideroblastic anaemias	0.001	0.998	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.001	0.998	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.001	0.998	0.000
D64.0 Hereditary sideroblastic anaemia	0.001	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.001
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.998	0.001
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.999	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.001	0.999	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.999	0.001
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.001	0.999	0.000
I10-I15 Hypertensive diseases	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.999	0.001
M65.34 Trigger finger-Hand	0.000	0.999	0.001
E23.2 Diabetes insipidus	0.001	0.999	0.000
H25.0 Senile incipient cataract	0.000	0.999	0.001
H72.8 Other perforations of tympanic membrane	0.000	0.999	0.001
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.999	0.001
H65-H75 Diseases of middle ear and mastoid	0.000	0.999	0.001
N60.3 Fibrosclerosis of breast	0.001	0.999	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.001	0.999	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.999	0.001
H72.1 Attic perforation of tympanic membrane	0.000	0.999	0.001
M25.8 Other specified joint disorders	0.001	0.999	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.999	0.001
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.999	0.001
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.999	0.001
T42.3 Barbiturates	0.000	0.999	0.001
T42.2 Succinimides and oxazolidinediones	0.000	0.999	0.001
T42.1 Iminostilbenes	0.000	0.999	0.001
T42.0 Hydantoin derivatives	0.000	0.999	0.001
M25.7 Osteophyte	0.001	0.999	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.999	0.001
R61.9 Hyperhidrosis, unspecified	0.001	0.999	0.000
H71 Cholesteatoma of middle ear	0.000	0.999	0.001
I15 Secondary hypertension	0.000	0.999	0.001
M25.42 Effusion of joint (Upper arm)	0.001	0.999	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.999	0.001
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.999	0.001
Z35.5 Supervision of elderly primigravida	0.000	0.999	0.001
M19.0 Primary arthrosis of other joints	0.000	0.999	0.001
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.001	0.999	0.000
I13 Hypertensive heart and renal disease	0.000	0.999	0.001
N60 Benign mammary dysplasia	0.001	0.999	0.000
M25.78 Osteophyte (Other)	0.001	0.999	0.000
E14.3 With ophthalmic complications	0.000	0.999	0.001
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.999	0.001
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.999	0.001
H68 Eustachian salpingitis and obstruction	0.000	0.999	0.001
H67 Otitis media in diseases classified elsewhere	0.000	0.999	0.001
D50-D53 Nutritional anaemias	0.001	0.999	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.001	0.999	0.000
M25.31 Other instability of joint (Shoulder region)	0.001	0.999	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.001	0.999	0.000
M25.88 Other specified joint disorders (Other)	0.001	0.999	0.000
M25.82 Other specified joint disorders (Upper arm)	0.001	0.999	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.001	0.999	0.000
M22.8 Other disorders of patella	0.001	0.999	0.000
N60.1 Diffuse cystic mastopathy	0.001	0.999	0.000
N60.0 Solitary cyst of breast	0.001	0.999	0.000
I11 Hypertensive heart disease	0.000	0.999	0.001
M25.79 Osteophyte (Site unspecified)	0.001	0.999	0.000
M25.73 Osteophyte (Forearm)	0.001	0.999	0.000
M25.70 Osteophyte (Multiple sites)	0.001	0.999	0.000
M25.84 Other specified joint disorders (Hand)	0.001	0.999	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.999	0.001
N60.8 Other benign mammary dysplasias	0.001	0.999	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.999	0.001
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.999	0.001
H25.9 Senile cataract, unspecified	0.000	0.999	0.001
I15.9 Seconday hypertension, unspecified	0.000	0.999	0.001
I15.8 Other secondary hypertension	0.000	0.999	0.001
I15.2 Hypertension secondary to endocrine disorders	0.000	0.999	0.001
I15.0 Renovascular hypertension	0.000	0.999	0.001
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.999	0.001
M25.72 Osteophyte (Upper arm)	0.001	0.999	0.000
S02.20 Fracture of nasal bones (closed)	0.001	0.999	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.001	0.999	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.000	0.999	0.001
H73 Other disorders of tympanic membrane	0.000	0.999	0.001
M19.08 Primary arthrosis of other joints (Other)	0.000	0.999	0.001
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.999	0.001
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.999	0.001
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.999	0.001
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.999	0.001
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations