TreeWAS – Variant ID: rs10168266

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	0.984	0.016	0.000
E00-E07 Disorders of thyroid gland	0.968	0.032	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.958	0.042	0.000
E05.9 Thyrotoxicosis, unspecified	0.940	0.060	0.000
E07 Other disorders of thyroid	0.835	0.165	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.822	0.178	0.000
E06 Thyroiditis	0.819	0.181	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.789	0.211	0.000
E03.8 Other specified hypothyroidism	0.783	0.217	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.772	0.228	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.732	0.268	0.000
E07.9 Disorder of thyroid, unspecified	0.730	0.270	0.000
E03.5 Myxoedema coma	0.705	0.295	0.000
E03.4 Atrophy of thyroid (acquired)	0.705	0.295	0.000
E03.3 Postinfectious hypothyroidism	0.705	0.295	0.000
E03.1 Congenital hypothyroidism without goitre	0.705	0.295	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.694	0.306	0.000
E00 Congenital iodine-deficiency syndrome	0.694	0.306	0.000
E05.5 Thyroid crisis or storm	0.687	0.313	0.000
E05.4 Thyrotoxicosis factitia	0.687	0.313	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.687	0.313	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.687	0.313	0.000
E06.9 Thyroiditis, unspecified	0.674	0.326	0.000
E06.3 Autoimmune thyroiditis	0.647	0.353	0.000
E07.8 Other specified disorders of thyroid	0.618	0.381	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.618	0.382	0.000
E05.8 Other thyrotoxicosis	0.605	0.395	0.000
E07.1 Dyshormogenetic goitre	0.598	0.401	0.000
E07.0 Hypersecretion of calcitonin	0.598	0.401	0.000
E06.5 Other chronic thyroiditis	0.587	0.413	0.000
E06.4 Drug-induced thyroiditis	0.587	0.413	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.587	0.413	0.000
E06.1 Subacute thyroiditis	0.587	0.413	0.000
E06.0 Acute thyroiditis	0.587	0.413	0.000
E04 Other non-toxic goitre	0.573	0.427	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.497	0.502	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.497	0.502	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.497	0.502	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.497	0.502	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.497	0.502	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.497	0.502	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.497	0.502	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.497	0.502	0.000
E04.0 Non-toxic diffuse goitre	0.480	0.520	0.000
E04.1 Non-toxic single thyroid nodule	0.442	0.558	0.000
E04.8 Other specified non-toxic goitre	0.411	0.589	0.000
E04.9 Non-toxic goitre, unspecified	0.298	0.702	0.000
E04.2 Non-toxic multinodular goitre	0.217	0.783	0.000
J34.3 Hypertrophy of nasal turbinates	0.000	0.915	0.085
J34 Other disorders of nose and nasal sinuses	0.000	0.948	0.052
M35.0 Sicca syndrome [Sjogren]	0.047	0.953	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.000	0.954	0.046
J34.0 Abscess, furuncle and carbuncle of nose	0.000	0.960	0.040
M35 Other systemic involvement of connective tissue	0.038	0.962	0.000
M35.3 Polymyalgia rheumatica	0.038	0.962	0.000
J34.2 Deviated nasal septum	0.000	0.963	0.037
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.966	0.034
M35.1 Other overlap syndromes	0.032	0.968	0.000
M35.8 Other specified systemic involvement of connective tissue	0.030	0.970	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.028	0.972	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.028	0.972	0.000
M35.5 Multifocal fibrosclerosis	0.028	0.972	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.028	0.972	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.026	0.974	0.000
M35.2 Behcet's disease	0.024	0.976	0.000
E50-E64 Other nutritional deficiencies	0.020	0.980	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.020	0.980	0.000
C18.7 Sigmoid colon	0.019	0.981	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.018	0.982	0.000
E40-E46 Malnutrition	0.018	0.982	0.000
E61 Deficiency of other nutrient elements	0.017	0.983	0.000
E55 Vitamin D deficiency	0.017	0.983	0.000
M35.7 Hypermobility syndrome	0.016	0.984	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.015	0.985	0.000
E63 Other nutritional deficiencies	0.015	0.985	0.000
E56 Other vitamin deficiencies	0.015	0.985	0.000
E51 Thiamine deficiency	0.015	0.985	0.000
E50 Vitamin A deficiency	0.015	0.985	0.000
E60 Dietary zinc deficiency	0.015	0.985	0.000
E59 Dietary selenium deficiency	0.015	0.985	0.000
E58 Dietary calcium deficiency	0.015	0.985	0.000
E54 Ascorbic acid deficiency	0.015	0.985	0.000
E52 Niacin deficiency [pellagra]	0.015	0.985	0.000
E20-E35 Disorders of other endocrine glands	0.015	0.985	0.000
E55.9 Vitamin D deficiency, unspecified	0.015	0.985	0.000
E61.2 Magnesium deficiency	0.014	0.986	0.000
E61.1 Iron deficiency	0.014	0.986	0.000
E15 Nondiabetic hypoglycaemic coma	0.013	0.987	0.000
E24 Cushing's syndrome	0.013	0.987	0.000
E27 Other disorders of adrenal gland	0.013	0.987	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.013	0.987	0.000
E45 Retarded development following protein-energy malnutrition	0.013	0.987	0.000
E43 Unspecified severe protein-energy malnutrition	0.013	0.987	0.000
E42 Marasmic kwashiorkor	0.013	0.987	0.000
E41 Nutritional marasmus	0.013	0.987	0.000
E40 Kwashiorkor	0.013	0.987	0.000
E27.1 Primary adrenocortical insufficiency	0.013	0.987	0.000
I73.0 Raynaud's syndrome	0.013	0.987	0.000
E16 Other disorders of pancreatic internal secretion	0.013	0.987	0.000
E61.9 Deficiency of nutrient element, unspecified	0.012	0.987	0.000
E61.8 Deficiency of other specified nutrient elements	0.012	0.987	0.000
E61.7 Deficiency of multiple nutrient elements	0.012	0.987	0.000
E61.6 Vanadium deficiency	0.012	0.987	0.000
E61.5 Molybdenum deficiency	0.012	0.987	0.000
E61.4 Chromium deficiency	0.012	0.987	0.000
E61.3 Manganese deficiency	0.012	0.987	0.000
E61.0 Copper deficiency	0.012	0.987	0.000
E55.0 Rickets, active	0.012	0.987	0.000
E65-E68 Obesity and other hyperalimentation	0.012	0.988	0.000
E46 Unspecified protein-energy malnutrition	0.012	0.988	0.000
E24.9 Cushing's syndrome, unspecified	0.012	0.988	0.000
R56.8 Other and unspecified convulsions	0.000	0.988	0.012
I49.5 Sick sinus syndrome	0.011	0.989	0.000
N03.9 Unspecified	0.011	0.989	0.000
E50.9 Vitamin A deficiency, unspecified	0.011	0.989	0.000
E50.8 Other manifestations of vitamin A deficiency	0.011	0.989	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.011	0.989	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.011	0.989	0.000
E50.5 Vitamin A deficiency with night blindness	0.011	0.989	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.011	0.989	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.011	0.989	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.011	0.989	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.011	0.989	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.011	0.989	0.000
E51.9 Thiamine deficiency, unspecified	0.011	0.989	0.000
E51.8 Other manifestations of thiamine deficiency	0.011	0.989	0.000
E51.2 Wernicke's encephalopathy	0.011	0.989	0.000
E51.1 Beriberi	0.011	0.989	0.000
E56.9 Vitamin deficiency, unspecified	0.011	0.989	0.000
E56.8 Deficiency of other vitamins	0.011	0.989	0.000
E56.1 Deficiency of vitamin K	0.011	0.989	0.000
E56.0 Deficiency of vitamin E	0.011	0.989	0.000
E63.9 Nutritional deficiency, unspecified	0.011	0.989	0.000
E63.8 Other specified nutritional deficiencies	0.011	0.989	0.000
E63.1 Imbalance of constituents of food intake	0.011	0.989	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.011	0.989	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.011	0.989	0.000
E64.8 Sequelae of other nutritional deficiencies	0.011	0.989	0.000
E64.3 Sequelae of rickets	0.011	0.989	0.000
E64.2 Sequelae of vitamin C deficiency	0.011	0.989	0.000
E64.1 Sequelae of vitamin A deficiency	0.011	0.989	0.000
E64.0 Sequelae of protein-energy malnutrition	0.011	0.989	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.011	0.989	0.000
E32 Diseases of thymus	0.011	0.989	0.000
E31 Polyglandular dysfunction	0.011	0.989	0.000
E30 Disorders of puberty, not elsewhere classified	0.011	0.989	0.000
E25 Adrenogenital disorders	0.011	0.989	0.000
E26 Hyperaldosteronism	0.011	0.989	0.000
E53 Deficiency of other B group vitamins	0.010	0.989	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.010	0.990	0.000
E29 Testicular dysfunction	0.010	0.990	0.000
E20 Hypoparathyroidism	0.010	0.990	0.000
E24.0 Pituitary-dependent Cushing's disease	0.010	0.990	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.010	0.990	0.000
E24.8 Other Cushing's syndrome	0.010	0.990	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.010	0.990	0.000
E24.3 Ectopic ACTH syndrome	0.010	0.990	0.000
E24.1 Nelson's syndrome	0.010	0.990	0.000
E27.5 Adrenomedullary hyperfunction	0.010	0.990	0.000
E27.0 Other adrenocortical overactivity	0.010	0.990	0.000
E16.1 Other hypoglycaemia	0.010	0.990	0.000
E44.1 Mild protein-energy malnutrition	0.009	0.990	0.000
E44.0 Moderate protein-energy malnutrition	0.009	0.990	0.000
E27.9 Disorder of adrenal gland, unspecified	0.010	0.990	0.000
E28 Ovarian dysfunction	0.010	0.990	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.009	0.991	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.009	0.991	0.000
E16.4 Abnormal secretion of gastrin	0.009	0.991	0.000
E16.3 Increased secretion of glucagon	0.009	0.991	0.000
E65 Localised adiposity	0.009	0.991	0.000
E24.2 Drug-induced Cushing's syndrome	0.009	0.991	0.000
E22 Hyperfunction of pituitary gland	0.009	0.991	0.000
E67 Other hyperalimentation	0.009	0.991	0.000
E68 Sequelae of hyperalimentation	0.009	0.991	0.000
E34 Other endocrine disorders	0.009	0.991	0.000
E16.2 Hypoglycaemia, unspecified	0.009	0.991	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.008	0.991	0.000
E23 Hypofunction and other disorders of pituitary gland	0.008	0.991	0.000
E27.2 Addisonian crisis	0.008	0.992	0.000
E53.9 Vitamin B deficiency, unspecified	0.008	0.992	0.000
E25.9 Adrenogenital disorder, unspecified	0.008	0.992	0.000
E25.8 Other adrenogenital disorders	0.008	0.992	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.008	0.992	0.000
E30.9 Disorder of puberty, unspecified	0.008	0.992	0.000
E30.8 Other disorders of puberty	0.008	0.992	0.000
E30.1 Precocious puberty	0.008	0.992	0.000
E30.0 Delayed puberty	0.008	0.992	0.000
E31.9 Polyglandular dysfunction, unspecified	0.008	0.992	0.000
E31.8 Other polyglandular dysfunction	0.008	0.992	0.000
E31.1 Polyglandular hyperfunction	0.008	0.992	0.000
E31.0 Autoimmune polyglandular failure	0.008	0.992	0.000
E32.9 Disease of thymus, unspecified	0.008	0.992	0.000
E32.8 Other diseases of thymus	0.008	0.992	0.000
E32.1 Abscess of thymus	0.008	0.992	0.000
E32.0 Persistent hyperplasia of thymus	0.008	0.992	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.008	0.992	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.008	0.992	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.008	0.992	0.000
E26.9 Hyperaldosteronism, unspecified	0.008	0.992	0.000
E26.8 Other hyperaldosteronism	0.008	0.992	0.000
E26.1 Secondary hyperaldosteronism	0.008	0.992	0.000
N95.2 Postmenopausal atrophic vaginitis	0.008	0.992	0.000
E26.0 Primary hyperaldosteronism	0.008	0.992	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.008	0.992	0.000
E53.1 Pyridoxine deficiency	0.008	0.992	0.000
E53.0 Riboflavin deficiency	0.008	0.992	0.000
K22.9 Disease of oesophagus, unspecified	0.008	0.992	0.000
E29.9 Testicular dysfunction, unspecified	0.007	0.992	0.000
E29.8 Other testicular dysfunction	0.007	0.992	0.000
E29.0 Testicular hyperfunction	0.007	0.992	0.000
E20.8 Other hypoparathyroidism	0.007	0.992	0.000
E20.1 Pseudohypoparathyroidism	0.007	0.992	0.000
E20.0 Idiopathic hypoparathyroidism	0.007	0.992	0.000
E27.8 Other specified disorders of adrenal gland	0.007	0.992	0.000
E22.1 Hyperprolactinaemia	0.007	0.992	0.000
E23.6 Other disorders of pituitary gland	0.007	0.993	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.007	0.993	0.000
E28.9 Ovarian dysfunction, unspecified	0.007	0.993	0.000
E28.8 Other ovarian dysfunction	0.007	0.993	0.000
E28.1 Androgen excess	0.007	0.993	0.000
E28.0 Oestrogen excess	0.007	0.993	0.000
E28.2 Polycystic ovarian syndrome	0.007	0.993	0.000
E20.9 Hypoparathyroidism, unspecified	0.007	0.993	0.000
E29.1 Testicular hypofunction	0.007	0.993	0.000
E21.2 Other hyperparathyroidism	0.007	0.993	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.007	0.993	0.000
E22.8 Other hyperfunction of pituitary gland	0.007	0.993	0.000
E67.8 Other specified hyperalimentation	0.007	0.993	0.000
E67.3 Hypervitaminosis D	0.007	0.993	0.000
E67.2 Megavitamin-B6 syndrome	0.007	0.993	0.000
E67.1 Hypercarotenaemia	0.007	0.993	0.000
E67.0 Hypervitaminosis A	0.007	0.993	0.000
E34.5 Androgen resistance syndrome	0.007	0.993	0.000
E34.4 Constitutional tall stature	0.007	0.993	0.000
E34.3 Short stature, not elsewhere classified	0.007	0.993	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.007	0.993	0.000
E34.1 Other hypersecretion of intestinal hormones	0.007	0.993	0.000
C18 Malignant neoplasm of colon	0.007	0.993	0.000
E34.9 Endocrine disorder, unspecified	0.007	0.993	0.000
C18.9 Colon, unspecified	0.007	0.993	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.006	0.994	0.000
E23.1 Drug-induced hypopituitarism	0.006	0.994	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.006	0.994	0.000
Z85.6 Personal history of leukaemia	0.000	0.994	0.006
E23.2 Diabetes insipidus	0.006	0.994	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.006	0.994	0.000
E34.0 Carcinoid syndrome	0.006	0.994	0.000
C18.5 Splenic flexure	0.006	0.994	0.000
M07.3 Other psoriatic arthropathies	0.006	0.994	0.000
E34.8 Other specified endocrine disorders	0.006	0.994	0.000
J43.9 Emphysema, unspecified	0.000	0.994	0.006
E21.4 Other specified disorders of parathyroid gland	0.006	0.994	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.006	0.994	0.000
C18.3 Hepatic flexure	0.006	0.994	0.000
E28.3 Primary ovarian failure	0.006	0.994	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.006	0.994	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.006	0.994	0.000
N03 Chronic nephritic syndrome	0.005	0.994	0.000
L90.0 Lichen sclerosus et atrophicus	0.005	0.995	0.000
C18.4 Transverse colon	0.005	0.995	0.000
E22.0 Acromegaly and pituitary gigantism	0.005	0.995	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.005	0.995	0.000
Z01.8 Other specified special examinations	0.000	0.995	0.005
R56 Convulsions, not elsewhere classified	0.000	0.995	0.005
E23.7 Disorder of pituitary gland, unspecified	0.005	0.995	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.005	0.995	0.000
R59.0 Localised enlarged lymph nodes	0.000	0.995	0.005
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.005	0.995	0.000
C18.2 Ascending colon	0.005	0.995	0.000
M07.38 Other psoriatic arthropathies (Other)	0.004	0.995	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.004	0.995	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.004	0.995	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.004	0.995	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.004	0.995	0.000
S22.1 Multiple fractures of thoracic spine	0.005	0.995	0.000
M25.56 Pain in joint (Lower leg)	0.000	0.996	0.004
C18.8 Overlapping lesion of colon	0.004	0.996	0.000
N03.8 Other	0.004	0.996	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.004	0.996	0.000
N03.6 Dense deposit disease	0.004	0.996	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.004	0.996	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.004	0.996	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.004	0.996	0.000
N03.2 Diffuse membranous glomerulonephritis	0.004	0.996	0.000
N03.1 Focal and segmental glomerular lesions	0.004	0.996	0.000
N03.0 Minor glomerular abnormality	0.004	0.996	0.000
F17.2 Dependence syndrome	0.000	0.996	0.004
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
S22.50 Flail chest (closed)	0.004	0.996	0.000
C18.1 Appendix	0.004	0.996	0.000
S22.5 Flail chest	0.004	0.996	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.004	0.996	0.000
R56.0 Febrile convulsions	0.000	0.996	0.004
M34.9 Systemic sclerosis, unspecified	0.004	0.996	0.000
Q61.9 Cystic kidney disease, unspecified	0.004	0.996	0.000
D59.1 Other autoimmune haemolytic anaemias	0.004	0.996	0.000
M07 Psoriatic and enteropathic arthropathies	0.004	0.996	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.003	0.996	0.000
C18.6 Descending colon	0.003	0.996	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.004	0.996	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.004	0.996	0.000
Q61.0 Congenital single renal cyst	0.004	0.996	0.000
S22.3 Fracture of rib	0.003	0.997	0.000
S22.2 Fracture of sternum	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
D23.6 Skin of upper limb, including shoulder	0.000	0.997	0.003
L92.0 Granuloma annulare	0.000	0.997	0.003
M06.9 Rheumatoid arthritis, unspecified	0.003	0.997	0.000
M34 Systemic sclerosis	0.003	0.997	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
S22.30 Fracture of rib (closed)	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.003	0.997	0.000
S22.51 Flail chest (open)	0.003	0.997	0.000
S22.9 Fracture of bony thorax, part unspecified	0.003	0.997	0.000
S22.8 Fracture of other parts of bony thorax	0.003	0.997	0.000
S22.20 Fracture of sternum (closed)	0.003	0.997	0.000
M34.1 CR(E)ST syndrome	0.003	0.997	0.000
R23.8 Other and unspecified skin changes	0.003	0.997	0.000
C50.3 Lower-inner quadrant of breast	0.003	0.997	0.000
K26.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
H53.2 Diplopia	0.003	0.997	0.000
M07.6 Other enteropathic arthropathies	0.003	0.997	0.000
M07.5 Arthropathy in ulcerative colitis	0.003	0.997	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.003	0.997	0.000
M07.2 Psoriatic spondylitis	0.003	0.997	0.000
M07.1 Arthritis mutilans	0.003	0.997	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
N42.2 Atrophy of prostate	0.003	0.997	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.997	0.003
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
S22.31 Fracture of rib (open)	0.003	0.997	0.000
S22.21 Fracture of sternum (open)	0.003	0.997	0.000
S22.0 Fracture of thoracic vertebra	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.997	0.003
D59 Acquired haemolytic anaemia	0.003	0.997	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.997	0.003
M34.2 Systemic sclerosis induced by drugs and chemicals	0.002	0.997	0.000
M34.0 Progressive systemic sclerosis	0.002	0.997	0.000
J43 Emphysema	0.000	0.997	0.003
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.997	0.003
S62.51 Fracture of thumb (open)	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.002	0.997	0.000
E66 Obesity	0.003	0.997	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.997	0.003
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.997	0.003
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.997	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.002	0.998	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.002	0.998	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.002	0.998	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.002	0.998	0.000
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
N50.1 Vascular disorders of male genital organs	0.002	0.998	0.000
Z01.7 Laboratory examination	0.000	0.998	0.002
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
G58.9 Mononeuropathy, unspecified	0.000	0.998	0.002
O62.2 Other uterine inertia	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.002	0.998	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.002	0.998	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.002	0.998	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.002	0.998	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.002	0.998	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.002	0.998	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.002	0.998	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.002	0.998	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.002	0.998	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.002	0.998	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.002	0.998	0.000
M07.18 Arthritis mutilans (Other)	0.002	0.998	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.002	0.998	0.000
M07.16 Arthritis mutilans (Lower leg)	0.002	0.998	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.002	0.998	0.000
M07.14 Arthritis mutilans (Hand)	0.002	0.998	0.000
M07.13 Arthritis mutilans (Forearm)	0.002	0.998	0.000
M07.12 Arthritis mutilans (Upper arm)	0.002	0.998	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.002	0.998	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.002	0.998	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.002	0.998	0.000
M07.28 Psoriatic spondylitis (Other)	0.002	0.998	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.002	0.998	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.002	0.998	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.002	0.998	0.000
M07.24 Psoriatic spondylitis (Hand)	0.002	0.998	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.002	0.998	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.002	0.998	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.002	0.998	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.002	0.998	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.002	0.998	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.002	0.998	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.002	0.998	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.002	0.998	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.002	0.998	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.002	0.998	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.002	0.998	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.002	0.998	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.002	0.998	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.002	0.998	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.002	0.998	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.002	0.998	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.002	0.998	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.002	0.998	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.002	0.998	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.002	0.998	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.002	0.998	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.002	0.998	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.002	0.998	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.002	0.998	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.002	0.998	0.000
M07.68 Other enteropathic arthropathies (Other)	0.002	0.998	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.002	0.998	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.002	0.998	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.002	0.998	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.002	0.998	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.002	0.998	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.002	0.998	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
S22.4 Multiple fractures of ribs	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
D41.4 Bladder	0.000	0.998	0.002
K75.4 Autoimmune hepatitis	0.002	0.998	0.000
R59 Enlarged lymph nodes	0.000	0.998	0.002
G47.9 Sleep disorder, unspecified	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
J43.2 Centrilobular emphysema	0.000	0.998	0.002
S22.01 Fracture of thoracic vertebra (open)	0.002	0.998	0.000
M05 Seropositive rheumatoid arthritis	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
E66.0 Obesity due to excess calories	0.002	0.998	0.000
J43.1 Panlobular emphysema	0.000	0.998	0.002
J43.0 MacLeod's syndrome	0.000	0.998	0.002
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.998	0.002
E66.1 Drug-induced obesity	0.002	0.998	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.998	0.002
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.998	0.002
X10.0 Home	0.002	0.998	0.000
S27.1 Traumatic haemothorax	0.002	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.002	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
J43.8 Other emphysema	0.000	0.998	0.002
M23.5 Chronic instability of knee	0.002	0.998	0.000
F10.4 Withdrawal state with delirium	0.000	0.998	0.002
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
G58.8 Other specified mononeuropathies	0.000	0.998	0.002
S22.41 Multiple fractures of ribs (open)	0.002	0.998	0.000
M06 Other rheumatoid arthritis	0.002	0.998	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.998	0.002
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
S21 Open wound of thorax	0.002	0.998	0.000
R57.2 Septic shock	0.000	0.998	0.002
S27.3 Other injuries of lung	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.000	0.998	0.002
M05.8 Other seropositive rheumatoid arthritis	0.002	0.998	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.998	0.000
M05.2 Rheumatoid vasculitis	0.002	0.998	0.000
M05.1 Rheumatoid lung disease	0.002	0.998	0.000
M05.0 Felty's syndrome	0.002	0.998	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.002	0.998	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.998	0.002
N42 Other disorders of prostate	0.002	0.998	0.000
N42.0 Calculus of prostate	0.002	0.998	0.000
Z01.6 Radiological examination, not elsewhere classified	0.000	0.998	0.002
M05-M14 Inflammatory polyarthropathies	0.002	0.998	0.000
R59.9 Enlarged lymph nodes, unspecified	0.000	0.998	0.002
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
L40.5 Arthropathic psoriasis	0.002	0.998	0.000
N42.8 Other specified disorders of prostate	0.002	0.998	0.000
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations