TreeWAS – Variant ID: rs10179986

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H53.9 Visual disturbance, unspecified	0.037	0.963	0.000
K63.8 Other specified diseases of intestine	0.020	0.980	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.982	0.018
H53.0 Amblyopia ex anopsia	0.017	0.983	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.984	0.016
C71.9 Brain, unspecified	0.015	0.985	0.000
H53 Visual disturbances	0.014	0.986	0.000
C71 Malignant neoplasm of brain	0.011	0.989	0.000
H53.6 Night blindness	0.011	0.989	0.000
H53.5 Colour vision deficiencies	0.011	0.989	0.000
H53.3 Other disorders of binocular vision	0.011	0.989	0.000
C71.3 Parietal lobe	0.010	0.990	0.000
H53.8 Other visual disturbances	0.009	0.991	0.000
C71.8 Overlapping lesion of brain	0.009	0.991	0.000
F05.9 Delirium, unspecified	0.009	0.991	0.000
C71.7 Brain stem	0.009	0.991	0.000
C71.6 Cerebellum	0.008	0.992	0.000
C71.5 Cerebral ventricle	0.008	0.992	0.000
H53.4 Visual field defects	0.008	0.992	0.000
C71.0 Cerebrum, except lobes and ventricles	0.008	0.992	0.000
C71.1 Frontal lobe	0.008	0.992	0.000
N20.1 Calculus of ureter	0.008	0.992	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.008	0.992	0.000
F05.0 Delirium not superimposed on dementia, so described	0.008	0.992	0.000
C71.2 Temporal lobe	0.007	0.993	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.007	0.993	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T21.0 Burn of unspecified degree of trunk	0.007	0.993	0.000
T21 Burn and corrosion of trunk	0.007	0.993	0.000
C71.4 Occipital lobe	0.007	0.993	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.007	0.993	0.000
T20.2 Burn of second degree of head and neck	0.007	0.993	0.000
T20 Burn and corrosion of head and neck	0.007	0.993	0.000
R21 Rash and other nonspecific skin eruption	0.000	0.993	0.007
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.007	0.993	0.000
C69 Malignant neoplasm of eye and adnexa	0.007	0.993	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
C70 Malignant neoplasm of meninges	0.006	0.994	0.000
N20 Calculus of kidney and ureter	0.006	0.994	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.006	0.994	0.000
Y42.7 Androgens and anabolic congeners	0.006	0.994	0.000
T21.3 Burn of third degree of trunk	0.006	0.994	0.000
D18.0 Haemangioma, any site	0.006	0.994	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
N20.0 Calculus of kidney	0.006	0.994	0.000
N41.0 Acute prostatitis	0.000	0.994	0.006
T21.2 Burn of second degree of trunk	0.006	0.994	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
C69.9 Eye, unspecified	0.006	0.994	0.000
F05.1 Delirium superimposed on dementia	0.005	0.994	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.006	0.994	0.000
C70.0 Cerebral meninges	0.005	0.994	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.005	0.994	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.005	0.994	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.005	0.994	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.005	0.994	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.005	0.994	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.005	0.994	0.000
T21.7 Corrosion of third degree of trunk	0.005	0.995	0.000
T21.6 Corrosion of second degree of trunk	0.005	0.995	0.000
T21.5 Corrosion of first degree of trunk	0.005	0.995	0.000
T21.4 Corrosion of unspecified degree of trunk	0.005	0.995	0.000
N20.9 Urinary calculus, unspecified	0.005	0.995	0.000
C69.3 Choroid	0.005	0.995	0.000
D47.2 Monoclonal gammopathy	0.005	0.995	0.000
C69.0 Conjunctiva	0.005	0.995	0.000
T20.7 Corrosion of third degree of head and neck	0.005	0.995	0.000
T20.6 Corrosion of second degree of head and neck	0.005	0.995	0.000
T20.5 Corrosion of first degree of head and neck	0.005	0.995	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.005	0.995	0.000
T20.3 Burn of third degree of head and neck	0.005	0.995	0.000
T23 Burn and corrosion of wrist and hand	0.005	0.995	0.000
F05.8 Other delirium	0.005	0.995	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.005	0.995	0.000
T20.1 Burn of first degree of head and neck	0.005	0.995	0.000
T21.1 Burn of first degree of trunk	0.005	0.995	0.000
F07.0 Organic personality disorder	0.005	0.995	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.005	0.995	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.005	0.995	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.005	0.995	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.005	0.995	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.005	0.995	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.005	0.995	0.000
I07.1 Tricuspid insufficiency	0.005	0.995	0.000
C69.8 Overlapping lesion of eye and adnexa	0.005	0.995	0.000
C69.6 Orbit	0.005	0.995	0.000
C69.5 Lachrymal gland and duct	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
C69.2 Retina	0.005	0.995	0.000
C69.1 Cornea	0.005	0.995	0.000
F03 Unspecified dementia	0.005	0.995	0.000
F06.7 Mild cognitive disorder	0.005	0.995	0.000
C70.9 Meninges, unspecified	0.005	0.995	0.000
C70.1 Spinal meninges	0.005	0.995	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.005	0.995	0.000
T20.0 Burn of unspecified degree of head and neck	0.004	0.995	0.000
C67 Malignant neoplasm of bladder	0.005	0.995	0.000
C67.6 Ureteric orifice	0.005	0.995	0.000
T25 Burn and corrosion of ankle and foot	0.004	0.995	0.000
C67.3 Anterior wall of bladder	0.005	0.995	0.000
F06.3 Organic mood [affective] disorders	0.005	0.995	0.000
N20.2 Calculus of kidney with calculus of ureter	0.005	0.995	0.000
T23.2 Burn of second degree of wrist and hand	0.004	0.996	0.000
C67.1 Dome of bladder	0.004	0.996	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.004	0.996	0.000
C72.9 Central nervous system, unspecified	0.004	0.996	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.996	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.996	0.000
C72.4 Acoustic nerve	0.004	0.996	0.000
C72.3 Optic nerve	0.004	0.996	0.000
C72.2 Olfactory nerve	0.004	0.996	0.000
C72.1 Cauda equina	0.004	0.996	0.000
F09 Unspecified organic or symptomatic mental disorder	0.004	0.996	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.004	0.996	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.996	0.004
C67.4 Posterior wall of bladder	0.004	0.996	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.004	0.996	0.000
F06.5 Organic dissociative disorder	0.004	0.996	0.000
F06.4 Organic anxiety disorder	0.004	0.996	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.004	0.996	0.000
F06.1 Organic catatonic disorder	0.004	0.996	0.000
F06.0 Organic hallucinosis	0.004	0.996	0.000
F02 Dementia in other diseases classified elsewhere	0.004	0.996	0.000
C72.0 Spinal cord	0.004	0.996	0.000
T23.1 Burn of first degree of wrist and hand	0.004	0.996	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
C67.2 Lateral wall of bladder	0.004	0.996	0.000
T23.7 Corrosion of third degree of wrist and hand	0.004	0.996	0.000
T23.6 Corrosion of second degree of wrist and hand	0.004	0.996	0.000
T23.5 Corrosion of first degree of wrist and hand	0.004	0.996	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.004	0.996	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.004	0.996	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.004	0.996	0.000
F07.1 Postencephalitic syndrome	0.004	0.996	0.000
G61.8 Other inflammatory polyneuropathies	0.004	0.996	0.000
G61.0 Guillain-Barre syndrome	0.004	0.996	0.000
D47.1 Chronic myeloproliferative disease	0.004	0.996	0.000
T23.3 Burn of third degree of wrist and hand	0.004	0.996	0.000
D47.4 Osteomyelofibrosis	0.004	0.996	0.000
B37.9 Candidiasis, unspecified	0.004	0.996	0.000
C67.9 Bladder, unspecified	0.004	0.996	0.000
C67.8 Overlapping lesion of bladder	0.004	0.996	0.000
C67.7 Urachus	0.003	0.996	0.000
G61 Inflammatory polyneuropathy	0.004	0.996	0.000
T25.7 Corrosion of third degree of ankle and foot	0.003	0.996	0.000
T25.6 Corrosion of second degree of ankle and foot	0.003	0.996	0.000
T25.5 Corrosion of first degree of ankle and foot	0.003	0.996	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.003	0.996	0.000
T25.1 Burn of first degree of ankle and foot	0.003	0.996	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.003	0.996	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
H53-H54 Visual disturbances and blindness	0.004	0.996	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.996	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.003	0.996	0.000
F01 Vascular dementia	0.003	0.997	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
F02.3 Dementia in Parkinson's disease	0.003	0.997	0.000
F02.0 Dementia in Pick's disease	0.003	0.997	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.003	0.997	0.000
T25.3 Burn of third degree of ankle and foot	0.003	0.997	0.000
C67.5 Bladder neck	0.003	0.997	0.000
F07.2 Postconcussional syndrome	0.003	0.997	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.003	0.997	0.000
F02.2 Dementia in Huntington's disease	0.003	0.997	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.003	0.997	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.997	0.003
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.003	0.997	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.003	0.997	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.003	0.997	0.000
G40 Epilepsy	0.003	0.997	0.000
T25.2 Burn of second degree of ankle and foot	0.003	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
C67.0 Trigone of bladder	0.003	0.997	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.003	0.997	0.000
W07.0 Home	0.000	0.997	0.003
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
G61.1 Serum neuropathy	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
G40.5 Special epileptic syndromes	0.003	0.997	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.003	0.997	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.003	0.997	0.000
F01.8 Other vascular dementia	0.003	0.997	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.003	0.997	0.000
F01.2 Subcortical vascular dementia	0.003	0.997	0.000
F01.1 Multi-infarct dementia	0.003	0.997	0.000
F01.0 Vascular dementia of acute onset	0.003	0.997	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
F00 Dementia in Alzheimer's disease	0.003	0.997	0.000
H10.9 Conjunctivitis, unspecified	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
H18.9 Disorder of cornea, unspecified	0.003	0.997	0.000
H92.1 Otorrhoea	0.000	0.997	0.003
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.997	0.003
H53.1 Subjective visual disturbances	0.002	0.997	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.002	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.997	0.000
F43.0 Acute stress reaction	0.000	0.997	0.003
D18 Haemangioma and lymphangioma, any site	0.003	0.997	0.000
C10.9 Oropharynx, unspecified	0.000	0.997	0.003
R74.8 Abnormal levels of other serum enzymes	0.003	0.997	0.000
J46 Status asthmaticus	0.003	0.997	0.000
K42 Umbilical hernia	0.000	0.997	0.003
D68.8 Other specified coagulation defects	0.002	0.998	0.000
G40.8 Other epilepsy	0.002	0.998	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.998	0.002
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.998	0.002
G40.7 Petit mal, unspecified, without grand mal seizures	0.002	0.998	0.000
B91 Sequelae of poliomyelitis	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
G81.9 Hemiplegia, unspecified	0.002	0.998	0.000
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.998	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
R20 Disturbances of skin sensation	0.000	0.998	0.002
D68 Other coagulation defects	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.998	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.998	0.002
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.000	0.998	0.002
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
J93.0 Spontaneous tension pneumothorax	0.002	0.998	0.000
K42.1 Umbilical hernia with gangrene	0.000	0.998	0.002
R20.0 Anaesthesia of skin	0.000	0.998	0.002
D18.1 Lymphangioma, any site	0.002	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.998	0.002
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.002	0.998	0.000
Y60.0 During surgical operation	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.998	0.002
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.998	0.002
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.998	0.002
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.998	0.002
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.998	0.002
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.998	0.002
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.998	0.002
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.998	0.002
I07.9 Tricuspid valve disease, unspecified	0.002	0.998	0.000
I07.8 Other tricuspid valve diseases	0.002	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.002	0.998	0.000
I07.0 Tricuspid stenosis	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
J93 Pneumothorax	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.000	0.998	0.002
C48.2 Peritoneum, unspecified	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
J93.9 Pneumothorax, unspecified	0.002	0.998	0.000
R20.1 Hypoaesthesia of skin	0.000	0.998	0.002
F01.9 Vascular dementia, unspecified	0.002	0.998	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.002	0.998	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.002	0.998	0.000
G40.9 Epilepsy, unspecified	0.002	0.998	0.000
R74 Abnormal serum enzyme levels	0.002	0.998	0.000
R20.3 Hyperaesthesia	0.000	0.998	0.002
D68.6 Other Thrombophilia	0.002	0.998	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.002	0.998	0.000
N30.0 Acute cystitis	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
H53.2 Diplopia	0.002	0.998	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
G00.1 Pneumococcal meningitis	0.000	0.998	0.002
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
C10 Malignant neoplasm of oropharynx	0.000	0.998	0.002
C48.0 Retroperitoneum	0.002	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
C01 Malignant neoplasm of base of tongue	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
R84.5 Abnormal microbiological findings	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.000	0.998	0.002
J93.8 Other pneumothorax	0.002	0.998	0.000
L85.9 Epidermal thickening, unspecified	0.000	0.998	0.002
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.002	0.998	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.002	0.998	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.998	0.002
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.001
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
D89.1 Cryoglobulinaemia	0.001	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.002	0.998	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.001	0.998	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.001	0.998	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.001	0.998	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.001	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.001	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
D89.3 Immune reconstitution syndrome	0.001	0.998	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.001	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.002	0.998	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.998	0.002
B94.9 Sequelae of unspecified infectious or parasitic disease	0.001	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.001
X49.9 Unspecified place	0.002	0.998	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y79.0 Diagnostic and monitoring devices	0.001	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
N25.8 Other disorders resulting from impaired renal tubular function	0.001	0.998	0.000
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.000	0.998	0.001
C10.8 Overlapping lesion of oropharynx	0.000	0.998	0.001
C10.4 Branchial cleft	0.000	0.998	0.001
C10.3 Posterior wall of oropharynx	0.000	0.998	0.001
C10.2 Lateral wall of oropharynx	0.000	0.998	0.001
C10.1 Anterior surface of epiglottis	0.000	0.998	0.001
C10.0 Vallecula	0.000	0.998	0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.001
C43.6 Malignant melanoma of upper limb, including shoulder	0.002	0.998	0.000
L91.0 Keloid scar	0.000	0.998	0.001
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.001	0.998	0.000
H54.0 Blindness, both eyes	0.001	0.999	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.999	0.001
H10 Conjunctivitis	0.001	0.999	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.999	0.001
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.001	0.999	0.000
K07.6 Temporomandibular joint disorders	0.001	0.999	0.000
C14.0 Pharynx, unspecified	0.000	0.999	0.001
C48.1 Specified parts of peritoneum	0.001	0.999	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
F80.1 Expressive language disorder	0.000	0.999	0.001
M34.1 CR(E)ST syndrome	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.999	0.001
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.999	0.001
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.999	0.001
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.999	0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.999	0.001
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.999	0.001
J20.9 Acute bronchitis, unspecified	0.000	0.999	0.001
Y79.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
C32.9 Larynx, unspecified	0.000	0.999	0.001
B94.8 Sequelae of other specified infectious and parasitic diseases	0.001	0.999	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.001	0.999	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.000	0.999	0.001
C68.0 Urethra	0.001	0.999	0.000
H10.4 Chronic conjunctivitis	0.001	0.999	0.000
B94.2 Sequelae of viral hepatitis	0.001	0.999	0.000
B94.1 Sequelae of viral encephalitis	0.001	0.999	0.000
B94.0 Sequelae of trachoma	0.001	0.999	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.999	0.001
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.999	0.001
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.999	0.000
F43.2 Adjustment disorders	0.000	0.999	0.001
H10.8 Other conjunctivitis	0.001	0.999	0.000
H10.5 Blepharoconjunctivitis	0.001	0.999	0.000
H10.2 Other acute conjunctivitis	0.001	0.999	0.000
H10.1 Acute atopic conjunctivitis	0.001	0.999	0.000
H10.0 Mucopurulent conjunctivitis	0.001	0.999	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.999	0.001
S64.8 Injury of other nerves at wrist and hand level	0.000	0.999	0.001
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.999	0.001
H54 Blindness and low vision	0.001	0.999	0.000
W07 Fall involving chair	0.000	0.999	0.001
H10.3 Acute conjunctivitis, unspecified	0.001	0.999	0.000
K83.0 Cholangitis	0.001	0.999	0.000
Q54.0 Hypospadias, balanic	0.001	0.999	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.001	0.999	0.000
F19.1 Harmful use	0.001	0.999	0.000
G06.1 Intraspinal abscess and granuloma	0.000	0.999	0.001
E28.3 Primary ovarian failure	0.000	0.999	0.001
H54.5 Low vision, one eye	0.001	0.999	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.000	0.999	0.001
U81.0 Vancomycin resistant agent	0.001	0.999	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.001	0.999	0.000
C02.1 Border of tongue	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
B90 Sequelae of tuberculosis	0.001	0.999	0.000
B92 Sequelae of leprosy	0.001	0.999	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.001	0.999	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.999	0.000
G47.9 Sleep disorder, unspecified	0.001	0.999	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.000	0.999	0.001
H54.3 Unqualified visual loss, both eyes	0.001	0.999	0.000
K09.2 Other cysts of jaw	0.001	0.999	0.000
W07.2 School, other institution and public administrative area	0.000	0.999	0.001
W07.8 Other specified place	0.000	0.999	0.001
W07.7 Farm	0.000	0.999	0.001
W07.6 Industrial and construction area	0.000	0.999	0.001
W07.5 Trade and service area	0.000	0.999	0.001
W07.4 Street and highway	0.000	0.999	0.001
W07.3 Sports and athletics area	0.000	0.999	0.001
W07.1 Residential institution	0.000	0.999	0.001
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.999	0.001
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
C32.0 Glottis	0.000	0.999	0.001
C34.0 Main bronchus	0.000	0.999	0.001
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
B80 Enterobiasis	0.001	0.999	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
C45.0 Mesothelioma of pleura	0.001	0.999	0.000
H54.2 Low vision, both eyes	0.001	0.999	0.000
K75.4 Autoimmune hepatitis	0.000	0.999	0.001
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.001	0.999	0.000
R20.2 Paraesthesia of skin	0.000	0.999	0.001
R23.3 Spontaneous ecchymoses	0.000	0.999	0.001
S51.0 Open wound of elbow	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000
C45 Mesothelioma	0.001	0.999	0.000
G00 Bacterial meningitis, not elsewhere classified	0.000	0.999	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.999	0.000
M54.16 Radiculopathy (Lumbar region)	0.001	0.999	0.000
B90.9 Sequelae of respiratory and unspecified tuberculosis	0.001	0.999	0.000
B90.8 Sequelae of tuberculosis of other organs	0.001	0.999	0.000
B90.2 Sequelae of tuberculosis of bones and joints	0.001	0.999	0.000
B90.1 Sequelae of genito-urinary tuberculosis	0.001	0.999	0.000
B90.0 Sequelae of central nervous system tuberculosis	0.001	0.999	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.999	0.001
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.001	0.999	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.001	0.999	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.001	0.999	0.000
Q50.3 Other congenital malformations of ovary	0.001	0.999	0.000
Q50.2 Congenital torsion of ovary	0.001	0.999	0.000
Q50.1 Developmental ovarian cyst	0.001	0.999	0.000
Q50.0 Congenital absence of ovary	0.001	0.999	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.999	0.001
C68 Malignant neoplasm of other and unspecified urinary organs	0.001	0.999	0.000
F43 Reaction to severe stress, and adjustment disorders	0.000	0.999	0.001
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.999	0.001
M54.12 Radiculopathy (Cervical region)	0.001	0.999	0.000
W07.29 Fall involving chair; School, other institution and public administrative area; During unspecified activity	0.000	0.999	0.001
C11.9 Nasopharynx, unspecified	0.000	0.999	0.001
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.000	0.999	0.001
C14.2 Waldeyer's ring	0.000	0.999	0.001
C45.7 Mesothelioma of other sites	0.001	0.999	0.000
C49.4 Connective and soft tissue of abdomen	0.001	0.999	0.000
D04.9 Skin, unspecified	0.001	0.999	0.000
G81 Hemiplegia	0.001	0.999	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.001	0.999	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
C45.9 Mesothelioma, unspecified	0.001	0.999	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.001	0.999	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.999	0.000
R23.2 Flushing	0.000	0.999	0.001
R82.9 Other and unspecified abnormal finding in urine	0.000	0.999	0.001
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.001	0.999	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.999	0.001
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
C45.2 Mesothelioma of pericardium	0.001	0.999	0.000
C45.1 Mesothelioma of peritoneum	0.001	0.999	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.999	0.001
G00.8 Other bacterial meningitis	0.000	0.999	0.001
G00.3 Staphylococcal meningitis	0.000	0.999	0.001
G00.0 Haemophilus meningitis	0.000	0.999	0.001
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
H54.1 Blindness, one eye, low vision, other eye	0.001	0.999	0.000
J15.4 Pneumonia due to other streptococci	0.001	0.999	0.000
M34.0 Progressive systemic sclerosis	0.001	0.999	0.000
N25.1 Nephrogenic diabetes insipidus	0.001	0.999	0.000
Q50.5 Embryonic cyst of broad ligament	0.001	0.999	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.000	0.999	0.001
S90.8 Other superficial injuries of ankle and foot	0.001	0.999	0.000
W07.9 Unspecified place	0.000	0.999	0.001
N20-N23 Urolithiasis	0.001	0.999	0.000
M13.94 Arthritis, unspecified (Hand)	0.001	0.999	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.001	0.999	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.001	0.999	0.000
C32.1 Supraglottis	0.000	0.999	0.001
C68.9 Urinary organ, unspecified	0.001	0.999	0.000
C68.8 Overlapping lesion of urinary organs	0.001	0.999	0.000
C68.1 Paraurethral glands	0.001	0.999	0.000
C81.9 Hodgkin's disease, unspecified	0.001	0.999	0.000
D40.1 Testis	0.000	0.999	0.001
F43.8 Other reactions to severe stress	0.000	0.999	0.001
J15.0 Pneumonia due to Klebsiella pneumoniae	0.001	0.999	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.001	0.999	0.000
N36.9 Urethral disorder, unspecified	0.001	0.999	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.999	0.001
M82 Osteoporosis in diseases classified elsewhere	0.000	0.999	0.001
M54.19 Radiculopathy (Site unspecified)	0.001	0.999	0.000
C49.5 Connective and soft tissue of pelvis	0.001	0.999	0.000
G81.0 Flaccid hemiplegia	0.001	0.999	0.000
K22.0 Achalasia of cardia	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations