TreeWAS – Variant ID: rs10183486

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H04 Disorders of lachrymal system	0.641	0.359	0.000
H04.2 Epiphora	0.632	0.368	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.627	0.373	0.000
H04.1 Other disorders of lachrymal gland	0.613	0.387	0.000
H04.9 Disorder of lachrymal system, unspecified	0.591	0.409	0.000
H04.8 Other disorders of lachrymal system	0.589	0.411	0.000
H04.0 Dacryoadenitis	0.490	0.510	0.000
H04.6 Other changes in lachrymal passages	0.471	0.529	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.399	0.601	0.000
H04.4 Chronic inflammation of lachrymal passages	0.371	0.629	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.091	0.909	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.077	0.923	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.071	0.929	0.000
H06.2 Dysthyroid exophthalmos	0.067	0.933	0.000
H05 Disorders of orbit	0.066	0.934	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.056	0.944	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.055	0.945	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.055	0.945	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.055	0.945	0.000
H01 Other inflammation of eyelid	0.055	0.945	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.053	0.947	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.051	0.949	0.000
H05.9 Disorder of orbit, unspecified	0.051	0.949	0.000
H05.0 Acute inflammation of orbit	0.051	0.949	0.000
H05.2 Exophthalmic conditions	0.049	0.951	0.000
H05.1 Chronic inflammatory disorders of orbit	0.048	0.951	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.048	0.952	0.000
H05.3 Deformity of orbit	0.048	0.952	0.000
H05.8 Other disorders of orbit	0.048	0.952	0.000
H01.8 Other specified inflammation of eyelid	0.046	0.953	0.000
H05.4 Enophthalmos	0.037	0.963	0.000
H01.9 Inflammation of eyelid, unspecified	0.034	0.965	0.000
H01.1 Non-infectious dermatoses of eyelid	0.034	0.966	0.000
H01.0 Blepharitis	0.031	0.969	0.000
H00 Hordeolum and chalazion	0.026	0.974	0.000
C15.5 Lower third of oesophagus	0.020	0.980	0.000
G47.9 Sleep disorder, unspecified	0.000	0.982	0.018
C15 Malignant neoplasm of oesophagus	0.014	0.986	0.000
C15.9 Oesophagus, unspecified	0.013	0.987	0.000
H11.3 Conjunctival haemorrhage	0.013	0.987	0.000
C15.0 Cervical part of oesophagus	0.011	0.989	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.989	0.011
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.989	0.011
C15.3 Upper third of oesophagus	0.011	0.989	0.000
O42 Premature rupture of membranes	0.000	0.990	0.010
C15.8 Overlapping lesion of oesophagus	0.010	0.990	0.000
C15.2 Abdominal part of oesophagus	0.010	0.990	0.000
C15.1 Thoracic part of oesophagus	0.010	0.990	0.000
H11 Other disorders of conjunctiva	0.010	0.990	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.990	0.010
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.990	0.010
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.990	0.010
C15.4 Middle third of oesophagus	0.010	0.990	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.009	0.990	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.010	0.990	0.000
H11.8 Other specified disorders of conjunctiva	0.009	0.991	0.000
H50.9 Strabismus, unspecified	0.009	0.991	0.000
H18.1 Bullous keratopathy	0.009	0.991	0.000
H10-H13 Disorders of conjunctiva	0.008	0.991	0.000
H21 Other disorders of iris and ciliary body	0.008	0.992	0.000
H18 Other disorders of cornea	0.008	0.992	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.992	0.008
H50 Other strabismus	0.008	0.992	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.008	0.992	0.000
H50.0 Convergent concomitant strabismus	0.008	0.992	0.000
Chapter VII Diseases of the eye and adnexa	0.008	0.992	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.008	0.992	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.008	0.992	0.000
H18.2 Other corneal oedema	0.007	0.993	0.000
H18.3 Changes in corneal membranes	0.007	0.993	0.000
H11.9 Disorder of conjunctiva, unspecified	0.007	0.993	0.000
H18.6 Keratoconus	0.007	0.993	0.000
H11.2 Conjunctival scars	0.007	0.993	0.000
H18.0 Corneal pigmentations and deposits	0.007	0.993	0.000
H11.1 Conjunctival degenerations and deposits	0.007	0.993	0.000
H21.0 Hyphaema	0.007	0.993	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.007	0.993	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.007	0.993	0.000
H49 Paralytic strabismus	0.007	0.993	0.000
H50.6 Mechanical strabismus	0.006	0.993	0.000
H17 Corneal scars and opacities	0.006	0.993	0.000
H18.4 Corneal degeneration	0.006	0.994	0.000
H21.4 Pupillary membranes	0.006	0.994	0.000
H50.8 Other specified strabismus	0.006	0.994	0.000
H49.2 Sixth [abducent] nerve palsy	0.006	0.994	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.006	0.994	0.000
H18.7 Other corneal deformities	0.006	0.994	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.006	0.994	0.000
H21.2 Degeneration of iris and ciliary body	0.006	0.994	0.000
H21.8 Other specified disorders of iris and ciliary body	0.006	0.994	0.000
H50.3 Intermittent heterotropia	0.006	0.994	0.000
H51 Other disorders of binocular movement	0.006	0.994	0.000
K12.2 Cellulitis and abscess of mouth	0.006	0.994	0.000
H49.8 Other paralytic strabismus	0.006	0.994	0.000
H50.5 Heterophoria	0.006	0.994	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.006	0.994	0.000
H20 Iridocyclitis	0.006	0.994	0.000
N64.1 Fat necrosis of breast	0.000	0.994	0.006
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.994	0.006
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.994	0.006
H20.8 Other iridocyclitis	0.005	0.995	0.000
H17.9 Corneal scar and opacity, unspecified	0.005	0.995	0.000
H49.9 Paralytic strabismus, unspecified	0.005	0.995	0.000
H15 Disorders of sclera	0.005	0.995	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.005	0.995	0.000
H00.1 Chalazion	0.005	0.995	0.000
H49.4 Progressive external ophthalmoplegia	0.005	0.995	0.000
K12.3 Oral mucositis (ulcerative)	0.005	0.995	0.000
S42.2 Fracture of upper end of humerus	0.000	0.995	0.005
N64.5 Other signs and symptoms in breast	0.000	0.995	0.005
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
N97.1 Female infertility of tubal origin	0.000	0.995	0.005
H49.3 Total (external) ophthalmoplegia	0.005	0.995	0.000
H50.4 Other and unspecified heterotropia	0.005	0.995	0.000
H51.9 Disorder of binocular movement, unspecified	0.005	0.995	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.995	0.005
H10 Conjunctivitis	0.005	0.995	0.000
H17.1 Other central corneal opacity	0.005	0.995	0.000
H17.0 Adherent leukoma	0.005	0.995	0.000
H02.0 Entropion and trichiasis of eyelid	0.005	0.995	0.000
H17.8 Other corneal scars and opacities	0.005	0.995	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
G47 Sleep disorders	0.000	0.995	0.005
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.005	0.995	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.005	0.995	0.000
H13.0 Filarial infection of conjunctiva	0.005	0.995	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.995	0.005
H50.2 Vertical strabismus	0.005	0.995	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
H02.5 Other disorders affecting eyelid function	0.005	0.995	0.000
H20.0 Acute and subacute iridocyclitis	0.005	0.995	0.000
F05.9 Delirium, unspecified	0.005	0.995	0.000
H51.8 Other specified disorders of binocular movement	0.004	0.995	0.000
H51.1 Convergence insufficiency and excess	0.004	0.995	0.000
H51.0 Palsy of conjugate gaze	0.004	0.995	0.000
K12 Stomatitis and related lesions	0.005	0.995	0.000
H13.3 Ocular pemphigoid	0.004	0.995	0.000
H10.1 Acute atopic conjunctivitis	0.004	0.995	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.004	0.995	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
H20.2 Lens-induced iridocyclitis	0.004	0.996	0.000
H51.2 Internuclear ophthalmoplegia	0.004	0.996	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.004	0.996	0.000
H18.8 Other specified disorders of cornea	0.004	0.996	0.000
H02 Other disorders of eyelid	0.004	0.996	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.996	0.004
H15.9 Disorder of sclera, unspecified	0.004	0.996	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.004	0.996	0.000
E86 Volume depletion	0.004	0.996	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
K12.0 Recurrent oral aphthae	0.004	0.996	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.004	0.996	0.000
H15.1 Episcleritis	0.004	0.996	0.000
H50.1 Divergent concomitant strabismus	0.004	0.996	0.000
H18.9 Disorder of cornea, unspecified	0.004	0.996	0.000
N64 Other disorders of breast	0.000	0.996	0.004
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.004	0.996	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.004	0.996	0.000
N97.9 Female infertility, unspecified	0.000	0.996	0.004
S42.21 Fracture of upper end of humerus (open)	0.000	0.996	0.004
H20.1 Chronic iridocyclitis	0.004	0.996	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
H10.8 Other conjunctivitis	0.004	0.996	0.000
H10.5 Blepharoconjunctivitis	0.004	0.996	0.000
H10.2 Other acute conjunctivitis	0.004	0.996	0.000
G47.8 Other sleep disorders	0.000	0.996	0.004
G47.3 Sleep apnoea	0.000	0.996	0.004
H10.3 Acute conjunctivitis, unspecified	0.004	0.996	0.000
H11.0 Pterygium	0.004	0.996	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.996	0.004
N36.8 Other specified disorders of urethra	0.000	0.996	0.004
M94.88 Other specified disorders of cartilage (Other)	0.004	0.996	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
G47.4 Narcolepsy and cataplexy	0.000	0.996	0.004
H10.0 Mucopurulent conjunctivitis	0.003	0.996	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
H15.8 Other disorders of sclera	0.003	0.996	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.003	0.996	0.000
H10.4 Chronic conjunctivitis	0.003	0.996	0.000
N64.4 Mastodynia	0.000	0.996	0.004
N97 Female infertility	0.000	0.996	0.004
H49.0 Third [oculomotor] nerve palsy	0.003	0.996	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.996	0.003
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
Y85.0 Sequelae of motor-vehicle accident	0.003	0.997	0.000
H40-H42 Glaucoma	0.003	0.997	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.003	0.997	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.003	0.997	0.000
H15.0 Scleritis	0.003	0.997	0.000
O02.1 Missed abortion	0.000	0.997	0.003
M94.8 Other specified disorders of cartilage	0.003	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.997	0.000
H49.1 Fourth [trochlear] nerve palsy	0.003	0.997	0.000
H46 Optic neuritis	0.003	0.997	0.000
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
D11.0 Parotid gland	0.000	0.997	0.003
N64.3 Galactorrhoea not associated with childbirth	0.000	0.997	0.003
N64.2 Atrophy of breast	0.000	0.997	0.003
N64.0 Fissure and fistula of nipple	0.000	0.997	0.003
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
C18.7 Sigmoid colon	0.000	0.997	0.003
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.997	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.003	0.997	0.000
G83.4 Cauda equina syndrome	0.000	0.997	0.003
F05 Delirium, not induced by alcohol and other psychoactive substances	0.003	0.997	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.003	0.997	0.000
C24.1 Ampulla of Vater	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.003	0.997	0.000
G47.2 Disorders of the sleep-wake schedule	0.000	0.997	0.003
N17.0 Acute renal failure with tubular necrosis	0.003	0.997	0.000
H55-H59 Other disorders of eye and adnexa	0.003	0.997	0.000
H43-H45 Disorders of vitreous body and globe	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.003	0.997	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.003	0.997	0.000
F05.8 Other delirium	0.003	0.997	0.000
N97.4 Female infertility associated with male factors	0.000	0.997	0.003
N97.3 Female infertility of cervical origin	0.000	0.997	0.003
N97.2 Female infertility of uterine origin	0.000	0.997	0.003
J36 Peritonsillar abscess	0.000	0.997	0.003
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.997	0.003
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.002	0.997	0.001
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.002	0.997	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.002	0.997	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.002	0.997	0.000
N97.8 Female infertility of other origin	0.000	0.997	0.003
H42 Glaucoma in diseases classified elsewhere	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.003	0.997	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.003	0.997	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.003	0.997	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.003	0.997	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
H16 Keratitis	0.002	0.997	0.000
M94.26 Chondromalacia (Lower leg)	0.003	0.997	0.000
O86 Other puerperal infections	0.000	0.997	0.003
O86.2 Urinary tract infection following delivery	0.000	0.997	0.002
M94 Other disorders of cartilage	0.002	0.997	0.000
M94.2 Chondromalacia	0.002	0.997	0.000
Z98.1 Arthrodesis status	0.003	0.997	0.000
H02.2 Lagophthalmos	0.002	0.997	0.000
N97.0 Female infertility associated with anovulation	0.000	0.997	0.002
O86.4 Pyrexia of unknown origin following delivery	0.000	0.998	0.002
F01 Vascular dementia	0.002	0.998	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.002	0.998	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.998	0.002
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.002	0.998	0.000
U88 Agent resistant to multiple antibiotics	0.002	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.000	0.998	0.002
H57.1 Ocular pain	0.002	0.998	0.000
O87 Venous complications in the puerperium	0.000	0.998	0.002
M23.30 Other meniscus derangements (Multiple sites)	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
Y85 Sequelae of transport accidents	0.002	0.998	0.000
F01.1 Multi-infarct dementia	0.002	0.998	0.000
D66 Hereditary factor VIII deficiency	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.002	0.998	0.000
D39.1 Ovary	0.000	0.998	0.002
H42.8 Glaucoma in other diseases classified elsewhere	0.002	0.998	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
O87.2 Haemorrhoids in the puerperium	0.000	0.998	0.002
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
K86.2 Cyst of pancreas	0.000	0.998	0.002
O87.0 Superficial thrombophlebitis in the puerperium	0.000	0.998	0.002
H16.4 Corneal neovascularisation	0.002	0.998	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.998	0.002
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
O02 Other abnormal products of conception	0.000	0.998	0.002
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.000	0.998	0.002
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.998	0.002
O87.8 Other venous complications in the puerperium	0.000	0.998	0.002
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.998	0.002
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.002	0.998	0.000
O86.8 Other specified puerperal infections	0.000	0.998	0.002
O86.3 Other genito-urinary tract infections following delivery	0.000	0.998	0.002
O85-O92 Complications predominantly related to the puerperium	0.000	0.998	0.002
M94.3 Chondrolysis	0.002	0.998	0.000
M94.1 Relapsing polychondritis	0.002	0.998	0.000
N64.9 Disorder of breast, unspecified	0.000	0.998	0.002
S32.0 Fracture of lumbar vertebra	0.000	0.998	0.002
U80 Agent resistant to penicillin and related antibiotics	0.002	0.998	0.000
M94.29 Chondromalacia (Site unspecified)	0.002	0.998	0.000
M94.28 Chondromalacia (Other)	0.002	0.998	0.000
M94.27 Chondromalacia (Ankle and foot)	0.002	0.998	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.002	0.998	0.000
M94.24 Chondromalacia (Hand)	0.002	0.998	0.000
M94.23 Chondromalacia (Forearm)	0.002	0.998	0.000
M94.22 Chondromalacia (Upper arm)	0.002	0.998	0.000
M94.21 Chondromalacia (Shoulder region)	0.002	0.998	0.000
M94.20 Chondromalacia (Multiple sites)	0.002	0.998	0.000
Z56.0 Unemployment, unspecified	0.002	0.998	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
F01.8 Other vascular dementia	0.002	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.998	0.000
F01.2 Subcortical vascular dementia	0.002	0.998	0.000
F01.0 Vascular dementia of acute onset	0.002	0.998	0.000
H16.8 Other keratitis	0.002	0.998	0.000
N81.3 Complete uterovaginal prolapse	0.000	0.998	0.002
U89 Agent resistant to other and unspecified antibiotics	0.002	0.998	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.002	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
H43.2 Crystalline deposits in vitreous body	0.002	0.998	0.000
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.002	0.998	0.000
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.002	0.998	0.000
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.002	0.998	0.000
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.002	0.998	0.000
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.002	0.998	0.000
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.002	0.998	0.000
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.002	0.998	0.000
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.002	0.998	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.002	0.998	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.002	0.998	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.002	0.998	0.000
O97 Death from sequelae of direct obstetric causes	0.000	0.998	0.002
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.998	0.002
O95 Obstetric death of unspecified cause	0.000	0.998	0.002
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.998	0.002
H16.9 Keratitis, unspecified	0.002	0.998	0.000
O87.9 Venous complication in the puerperium, unspecified	0.000	0.998	0.002
O87.3 Cerebral venous thrombosis in the puerperium	0.000	0.998	0.002
O87.1 Deep phlebothrombosis in the puerperium	0.000	0.998	0.002
U89.9 Agent resistant to unspecified antibiotic	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.998	0.000
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.001	0.998	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.998	0.002
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
K86 Other diseases of pancreas	0.000	0.998	0.002
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
O86.1 Other infection of genital tract following delivery	0.000	0.998	0.002
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
G83.2 Monoplegia of upper limb	0.000	0.998	0.002
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.002	0.998	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.002	0.998	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.002	0.998	0.000
O02.9 Abnormal product of conception, unspecified	0.000	0.998	0.002
O02.8 Other specified abnormal products of conception	0.000	0.998	0.002
O92.1 Cracked nipple associated with childbirth	0.000	0.998	0.002
H47.2 Optic atrophy	0.002	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.998	0.002
O85 Puerperal sepsis	0.000	0.998	0.002
H25-H28 Disorders of lens	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.001	0.998	0.000
O92.7 Other and unspecified disorders of lactation	0.000	0.998	0.002
O92.6 Galactorrhoea	0.000	0.998	0.002
O92.5 Suppressed lactation	0.000	0.998	0.002
O92.4 Hypogalactia	0.000	0.998	0.002
O92.3 Agalactia	0.000	0.998	0.002
O92.0 Retracted nipple associated with childbirth	0.000	0.998	0.002
G83 Other paralytic syndromes	0.000	0.998	0.002
M94.9 Disorder of cartilage, unspecified	0.001	0.998	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.002	0.998	0.000
O90 Complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
O88 Obstetric embolism	0.000	0.998	0.002
M94.19 Relapsing polychondritis (Site unspecified)	0.002	0.998	0.000
M94.18 Relapsing polychondritis (Other)	0.002	0.998	0.000
M94.17 Relapsing polychondritis (Ankle and foot)	0.002	0.998	0.000
M94.16 Relapsing polychondritis (Lower leg)	0.002	0.998	0.000
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.002	0.998	0.000
M94.14 Relapsing polychondritis (Hand)	0.002	0.998	0.000
M94.13 Relapsing polychondritis (Forearm)	0.002	0.998	0.000
M94.12 Relapsing polychondritis (Upper arm)	0.002	0.998	0.000
M94.11 Relapsing polychondritis (Shoulder region)	0.002	0.998	0.000
M94.10 Relapsing polychondritis (Multiple sites)	0.002	0.998	0.000
M94.39 Chondrolysis (Site unspecified)	0.002	0.998	0.000
M94.38 Chondrolysis (Other)	0.002	0.998	0.000
M94.37 Chondrolysis (Ankle and foot)	0.002	0.998	0.000
M94.36 Chondrolysis (Lower leg)	0.002	0.998	0.000
M94.35 Chondrolysis (Pelvic region and thigh)	0.002	0.998	0.000
M94.34 Chondrolysis (Hand)	0.002	0.998	0.000
M94.33 Chondrolysis (Forearm)	0.002	0.998	0.000
M94.32 Chondrolysis (Upper arm)	0.002	0.998	0.000
M94.31 Chondrolysis (Shoulder region)	0.002	0.998	0.000
M94.30 Chondrolysis (Multiple sites)	0.002	0.998	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.998	0.002
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
I15.1 Hypertension secondary to other renal disorders	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.002	0.998	0.000
S10.9 Superficial injury of neck, part unspecified	0.002	0.998	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.000	0.998	0.002
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.002	0.998	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
U84 Resistance to other antimicrobial drugs	0.002	0.998	0.000
U83 Resistance to other antibiotics	0.002	0.998	0.000
U82 Resistance to betalactam antibiotics	0.002	0.998	0.000
U85 Resistance to antineoplastic drugs	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.000	0.998	0.001
O96.1 Death from indirect obstetric cause	0.000	0.998	0.001
O96.0 Death from direct obstetric cause	0.000	0.998	0.001
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.998	0.001
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.998	0.001
O97.0 Death from sequelae of direct obstetric cause	0.000	0.998	0.001
H53-H54 Visual disturbances and blindness	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
C24.0 Extrahepatic bile duct	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.998	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.998	0.002
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.001	0.998	0.000
H47.6 Disorders of visual cortex	0.001	0.998	0.000
H47.5 Disorders of other visual pathways	0.001	0.998	0.000
H47.4 Disorders of optic chiasm	0.001	0.998	0.000
Z90.3 Acquired absence of part of stomach	0.002	0.998	0.000
H27 Other disorders of lens	0.002	0.998	0.000
D07.1 Vulva	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.001	0.998	0.000
O91 Infections of breast associated with childbirth	0.000	0.998	0.002
G24.5 Blepharospasm	0.000	0.998	0.002
G83.8 Other specified paralytic syndromes	0.000	0.998	0.002
H27.1 Dislocation of lens	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
N62 Hypertrophy of breast	0.000	0.998	0.002
O89 Complications of anaesthesia during the puerperium	0.000	0.998	0.001
C25.2 Tail of pancreas	0.002	0.998	0.000
H27.0 Aphakia	0.002	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.001	0.998	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
L03.1 Cellulitis of other parts of limb	0.002	0.998	0.000
O90.9 Complication of the puerperium, unspecified	0.000	0.998	0.002
O90.2 Haematoma of obstetric wound	0.000	0.998	0.001
S32.4 Fracture of acetabulum	0.000	0.998	0.002
F09 Unspecified organic or symptomatic mental disorder	0.001	0.998	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.001	0.998	0.000
F11.2 Dependence syndrome	0.002	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
H43 Disorders of vitreous body	0.002	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
C25.1 Body of pancreas	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
G83.5 Locked-in syndrome	0.000	0.998	0.001
G83.3 Monoplegia, unspecified	0.000	0.998	0.001
G83.1 Monoplegia of lower limb	0.000	0.998	0.002
G83.0 Diplegia of upper limbs	0.000	0.998	0.001
H31.1 Choroidal degeneration	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.001	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.000	0.998	0.001
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.001	0.998	0.000
M94.98 Disorder of cartilage, unspecified (Other)	0.001	0.998	0.000
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.001	0.998	0.000
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M94.94 Disorder of cartilage, unspecified (Hand)	0.001	0.998	0.000
M94.93 Disorder of cartilage, unspecified (Forearm)	0.001	0.998	0.000
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.001	0.998	0.000
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.001	0.998	0.000
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.001	0.998	0.000
C24.8 Overlapping lesion of biliary tract	0.001	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations