TreeWAS – Variant ID: rs10221903

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M43.16 Spondylolisthesis (Lumbar region)	1.000	0.000	0.000
M43.1 Spondylolisthesis	1.000	0.000	0.000
M40-M43 Deforming dorsopathies	1.000	0.000	0.000
M43 Other deforming dorsopathies	1.000	0.000	0.000
M48.06 Spinal stenosis (Lumbar region)	0.999	0.001	0.000
M48.0 Spinal stenosis	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002	0.000
M48 Other spondylopathies	0.996	0.004	0.000
M41 Scoliosis	0.994	0.006	0.000
M45-M49 Spondylopathies	0.994	0.006	0.000
M48.02 Spinal stenosis (Cervical region)	0.990	0.010	0.000
M41.9 Scoliosis, unspecified	0.989	0.011	0.000
M50-M54 Other dorsopathies	0.987	0.013	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.982	0.018	0.000
M54.1 Radiculopathy	0.975	0.025	0.000
M54 Dorsalgia	0.974	0.026	0.000
M05-M14 Inflammatory polyarthropathies	0.974	0.026	0.000
M54.16 Radiculopathy (Lumbar region)	0.970	0.030	0.000
M13 Other arthritis	0.968	0.032	0.000
M13.9 Arthritis, unspecified	0.960	0.040	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.958	0.042	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.948	0.052	0.000
M54.8 Other dorsalgia	0.901	0.099	0.000
M50 Cervical disk disorders	0.901	0.099	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.884	0.116	0.000
M50.1 Cervical disk disorder with radiculopathy	0.875	0.125	0.000
M12 Other specific arthropathies	0.872	0.128	0.000
M50.0 Cervical disk disorder with myelopathy	0.868	0.132	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.868	0.132	0.000
M54.19 Radiculopathy (Site unspecified)	0.864	0.136	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.863	0.137	0.000
M60-M63 Disorders of muscles	0.859	0.141	0.000
M13.93 Arthritis, unspecified (Forearm)	0.857	0.143	0.000
M48.8 Other specified spondylopathies	0.853	0.147	0.000
M54.12 Radiculopathy (Cervical region)	0.835	0.165	0.000
M41.8 Other forms of scoliosis	0.828	0.172	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.808	0.192	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.800	0.200	0.000
M13.1 Monoarthritis, not elsewhere classified	0.793	0.207	0.000
M13.8 Other specified arthritis	0.775	0.225	0.000
M48.04 Spinal stenosis (Thoracic region)	0.773	0.227	0.000
M65-M68 Disorders of synovium and tendon	0.769	0.231	0.000
M54.14 Radiculopathy (Thoracic region)	0.761	0.239	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.759	0.241	0.000
M08 Juvenile arthritis	0.753	0.247	0.000
M12.3 Palindromic rheumatism	0.753	0.247	0.000
M54.86 Other dorsalgia (Lumbar region)	0.749	0.251	0.000
M86-M90 Other osteopathies	0.749	0.251	0.000
M43.9 Deforming dorsopathy, unspecified	0.744	0.256	0.000
M43.6 Torticollis	0.742	0.258	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.741	0.259	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.740	0.260	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.735	0.265	0.000
M54.84 Other dorsalgia (Thoracic region)	0.733	0.267	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.731	0.269	0.000
M60 Myositis	0.726	0.274	0.000
M43.12 Spondylolisthesis (Cervical region)	0.726	0.274	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.725	0.274	0.000
M43.2 Other fusion of spine	0.724	0.276	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.723	0.277	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.723	0.277	0.000
M10 Gout	0.721	0.279	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.717	0.283	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.717	0.283	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.717	0.283	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.717	0.283	0.000
M42 Spinal osteochondrosis	0.717	0.283	0.000
M43.8 Other specified deforming dorsopathies	0.717	0.283	0.000
M43.5 Other recurrent vertebral subluxation	0.717	0.283	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.717	0.283	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.717	0.283	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.716	0.284	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.716	0.284	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.716	0.284	0.000
M48.4 Fatigue fracture of vertebra	0.714	0.286	0.000
M48.3 Traumatic spondylopathy	0.714	0.286	0.000
M48.2 Kissing spine	0.714	0.286	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.714	0.286	0.000
M43.0 Spondylolysis	0.714	0.286	0.000
M41.4 Neuromuscular scoliosis	0.713	0.287	0.000
M41.3 Thoracogenic scoliosis	0.713	0.287	0.000
M41.2 Other idiopathic scoliosis	0.713	0.287	0.000
M41.1 Juvenile idiopathic scoliosis	0.713	0.287	0.000
M41.0 Infantile idiopathic scoliosis	0.713	0.287	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.713	0.287	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.709	0.291	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.709	0.291	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.709	0.291	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.706	0.294	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.699	0.301	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.699	0.301	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.699	0.301	0.000
M54.0 Panniculitis affecting regions of neck and back	0.699	0.301	0.000
M54.89 Other dorsalgia (Site unspecified)	0.698	0.301	0.000
M67 Other disorders of synovium and tendon	0.698	0.302	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.698	0.302	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.694	0.306	0.000
M48.9 Spondylopathy, unspecified	0.693	0.307	0.000
M00-M03 Infectious arthropathies	0.681	0.319	0.000
M54.5 Low back pain	0.679	0.321	0.000
M62 Other disorders of muscle	0.677	0.323	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.675	0.325	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.672	0.328	0.000
M67.8 Other specified disorders of synovium and tendon	0.671	0.329	0.000
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.668	0.331	0.000
M13.98 Arthritis, unspecified (Other)	0.666	0.333	0.000
M07 Psoriatic and enteropathic arthropathies	0.665	0.335	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.664	0.336	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.658	0.342	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.657	0.343	0.000
M41.5 Other secondary scoliosis	0.655	0.345	0.000
M11 Other crystal arthropathies	0.655	0.345	0.000
M13.0 Polyarthritis, unspecified	0.650	0.350	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.648	0.352	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.646	0.354	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.646	0.354	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.646	0.354	0.000
M54.82 Other dorsalgia (Cervical region)	0.646	0.354	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.646	0.354	0.000
M12.2 Villonodular synovitis (pigmented)	0.646	0.354	0.000
M90 Osteopathies in diseases classified elsewhere	0.643	0.357	0.000
M49 Spondylopathies in diseases classified elsewhere	0.639	0.361	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.637	0.363	0.000
M54.6 Pain in thoracic spine	0.637	0.363	0.000
M99 Biomechanical lesions, not elsewhere classified	0.633	0.367	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.633	0.367	0.000
M88 Paget's disease of bone [osteitis deformans]	0.630	0.370	0.000
M54.50 Low back pain (Multiple sites in spine)	0.628	0.372	0.000
M12.5 Traumatic arthropathy	0.625	0.375	0.000
M12.4 Intermittent hydrarthrosis	0.625	0.375	0.000
M12.1 Kaschin-Beck disease	0.625	0.375	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.625	0.375	0.000
M13.80 Other specified arthritis (Multiple sites)	0.619	0.381	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.616	0.384	0.000
M61 Calcification and ossification of muscle	0.616	0.384	0.000
M51 Other intervertebral disk disorders	0.615	0.385	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.611	0.389	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.611	0.389	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.611	0.389	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.611	0.389	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.611	0.389	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.611	0.389	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.611	0.389	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.611	0.389	0.000
M54.57 Low back pain (Lumbosacral region)	0.607	0.393	0.000
M50.8 Other cervical disk disorders	0.603	0.397	0.000
M13.84 Other specified arthritis (Hand)	0.599	0.401	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.598	0.402	0.000
M08.0 Juvenile rheumatoid arthritis	0.595	0.405	0.000
M60.0 Infective myositis	0.594	0.406	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.593	0.407	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.593	0.407	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.593	0.407	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.593	0.407	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.593	0.407	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.593	0.407	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.593	0.407	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.593	0.407	0.000
M66 Spontaneous rupture of synovium and tendon	0.592	0.408	0.000
M12.88 Other specific arthropathies, not elsewhere classified (Other)	0.588	0.412	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.587	0.413	0.000
M14 Arthropathies in other diseases classified elsewhere	0.586	0.414	0.000
M80-M85 Disorders of bone density and structure	0.584	0.416	0.000
M40 Kyphosis and lordosis	0.584	0.416	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.584	0.416	0.000
M43.09 Spondylolysis (Site unspecified)	0.579	0.421	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.578	0.421	0.000
M13.86 Other specified arthritis (Lower leg)	0.578	0.421	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.570	0.430	0.000
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)	0.569	0.431	0.000
M13.18 Monoarthritis, not elsewhere classified (Other)	0.569	0.431	0.000
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)	0.569	0.431	0.000
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)	0.569	0.431	0.000
M13.14 Monoarthritis, not elsewhere classified (Hand)	0.569	0.431	0.000
M13.13 Monoarthritis, not elsewhere classified (Forearm)	0.569	0.431	0.000
M13.12 Monoarthritis, not elsewhere classified (Upper arm)	0.569	0.431	0.000
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)	0.569	0.431	0.000
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)	0.569	0.431	0.000
M43.99 Deforming dorsopathy, unspecified (Site unspecified)	0.560	0.440	0.000
M13.88 Other specified arthritis (Other)	0.556	0.444	0.000
M13.85 Other specified arthritis (Pelvic region and thigh)	0.556	0.444	0.000
M13.83 Other specified arthritis (Forearm)	0.556	0.444	0.000
M13.82 Other specified arthritis (Upper arm)	0.556	0.444	0.000
M13.81 Other specified arthritis (Shoulder region)	0.556	0.444	0.000
M67.1 Other contracture of tendon (sheath)	0.555	0.445	0.000
M43.62 Torticollis-Cervical	0.555	0.445	0.000
M60.9 Myositis, unspecified	0.553	0.447	0.000
M95.2 Other acquired deformity of head	0.552	0.448	0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified	0.551	0.448	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.551	0.448	0.000
M53 Other dorsopathies, not elsewhere classified	0.551	0.449	0.000
M43.06 Spondylolysis (Lumbar region)	0.549	0.451	0.000
M10.3 Gout due to impairment of renal function	0.549	0.451	0.000
M10.0 Idiopathic gout	0.549	0.451	0.000
M08.9 Juvenile arthritis, unspecified	0.540	0.460	0.000
M08.8 Other juvenile arthritis	0.540	0.460	0.000
M08.4 Pauciarticular juvenile arthritis	0.540	0.460	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.540	0.460	0.000
M08.2 Juvenile arthritis with systemic onset	0.540	0.460	0.000
M08.1 Juvenile ankylosing spondylitis	0.540	0.460	0.000
M12.38 Palindromic rheumatism (Other)	0.540	0.460	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.540	0.460	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.540	0.460	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.540	0.460	0.000
M12.34 Palindromic rheumatism (Hand)	0.540	0.460	0.000
M12.33 Palindromic rheumatism (Forearm)	0.540	0.460	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.540	0.460	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.540	0.460	0.000
M51.9 Intervertebral disk disorder, unspecified	0.539	0.461	0.000
M43.69 Torticollis-Site unspe	0.535	0.465	0.000
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.533	0.467	0.000
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)	0.533	0.467	0.000
M43.96 Deforming dorsopathy, unspecified (Lumbar region)	0.533	0.467	0.000
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)	0.533	0.467	0.000
M43.94 Deforming dorsopathy, unspecified (Thoracic region)	0.533	0.467	0.000
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)	0.533	0.467	0.000
M43.92 Deforming dorsopathy, unspecified (Cervical region)	0.533	0.467	0.000
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)	0.533	0.467	0.000
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)	0.533	0.467	0.000
M62.8 Other specified disorders of muscle	0.533	0.467	0.000
M88.9 Paget's disease of bone, unspecified	0.533	0.467	0.000
M02 Reactive arthropathies	0.532	0.467	0.000
M43.68 Torticollis-Sacral/sacrococ	0.532	0.468	0.000
M43.67 Torticollis-Lumbosacral	0.532	0.468	0.000
M43.66 Torticollis-Lumbar	0.532	0.468	0.000
M43.65 Torticollis-Thoracolumbar	0.532	0.468	0.000
M43.64 Torticollis-Thoracic	0.532	0.468	0.000
M43.63 Torticollis-Cervicothoracic	0.532	0.468	0.000
M43.61 Torticollis-Occipit-atl-axl	0.532	0.468	0.000
M43.60 Torticollis-Mult site	0.532	0.468	0.000
M43.26 Other fusion of spine (Lumbar region)	0.529	0.471	0.000
M54.3 Sciatica	0.528	0.472	0.000
M62.6 Muscle strain	0.525	0.475	0.000
M07.6 Other enteropathic arthropathies	0.525	0.475	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.524	0.476	0.000
M81 Osteoporosis without pathological fracture	0.522	0.478	0.000
M60.8 Other myositis	0.521	0.479	0.000
M60.1 Interstitial myositis	0.521	0.479	0.000
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.519	0.481	0.000
M43.27 Other fusion of spine (Lumbosacral region)	0.519	0.481	0.000
M43.25 Other fusion of spine (Thoracolumbar region)	0.519	0.481	0.000
M43.24 Other fusion of spine (Thoracic region)	0.519	0.481	0.000
M43.23 Other fusion of spine (Cervicothoracic region)	0.519	0.481	0.000
M43.22 Other fusion of spine (Cervical region)	0.519	0.481	0.000
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.519	0.481	0.000
M43.20 Other fusion of spine (Multiple sites in spine)	0.519	0.481	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.518	0.481	0.000
M10.4 Other secondary gout	0.517	0.483	0.000
M10.2 Drug-induced gout	0.517	0.483	0.000
M10.1 Lead-induced gout	0.517	0.483	0.000
M43.29 Other fusion of spine (Site unspecified)	0.516	0.483	0.000
M67.0 Short Achilles tendon (acquired)	0.515	0.485	0.000
M90.7 Fracture of bone in neoplastic disease	0.514	0.486	0.000
M42.9 Spinal osteochondrosis, unspecified	0.514	0.486	0.000
M42.1 Adult osteochondrosis of spine	0.514	0.486	0.000
M42.0 Juvenile osteochondrosis of spine	0.514	0.486	0.000
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.514	0.486	0.000
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.514	0.486	0.000
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.514	0.486	0.000
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.514	0.486	0.000
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.514	0.486	0.000
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.514	0.486	0.000
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.514	0.486	0.000
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.514	0.486	0.000
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.514	0.486	0.000
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.514	0.486	0.000
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.514	0.486	0.000
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.514	0.486	0.000
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.514	0.486	0.000
M43.46 Other recurrent atlantoaxial subluxation-Lumbar	0.514	0.486	0.000
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar	0.514	0.486	0.000
M43.44 Other recurrent atlantoaxial subluxation-Thoracic	0.514	0.486	0.000
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic	0.514	0.486	0.000
M43.42 Other recurrent atlantoaxial subluxation-Cervical	0.514	0.486	0.000
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl	0.514	0.486	0.000
M43.40 Other recurrent atlantoaxial subluxation-Mult site	0.514	0.486	0.000
M43.59 Other recurrent vertebral subluxation (Site unspecified)	0.514	0.486	0.000
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)	0.514	0.486	0.000
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)	0.514	0.486	0.000
M43.56 Other recurrent vertebral subluxation (Lumbar region)	0.514	0.486	0.000
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)	0.514	0.486	0.000
M43.54 Other recurrent vertebral subluxation (Thoracic region)	0.514	0.486	0.000
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)	0.514	0.486	0.000
M43.52 Other recurrent vertebral subluxation (Cervical region)	0.514	0.486	0.000
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl	0.514	0.486	0.000
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)	0.514	0.486	0.000
M43.89 Other specified deforming dorsopathies (Site unspecified)	0.514	0.486	0.000
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)	0.514	0.486	0.000
M43.87 Other specified deforming dorsopathies (Lumbosacral region)	0.514	0.486	0.000
M43.86 Other specified deforming dorsopathies (Lumbar region)	0.514	0.486	0.000
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)	0.514	0.486	0.000
M43.84 Other specified deforming dorsopathies (Thoracic region)	0.514	0.486	0.000
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)	0.514	0.486	0.000
M43.82 Other specified deforming dorsopathies (Cervical region)	0.514	0.486	0.000
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)	0.514	0.486	0.000
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)	0.514	0.486	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.513	0.487	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.512	0.488	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.512	0.488	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.512	0.488	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.512	0.488	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.512	0.488	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.512	0.488	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.512	0.488	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.512	0.488	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.512	0.488	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.512	0.488	0.000
M48.29 Kissing spine (Site unspecified)	0.512	0.488	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.512	0.488	0.000
M48.27 Kissing spine (Lumbosacral region)	0.512	0.488	0.000
M48.26 Kissing spine (Lumbar region)	0.512	0.488	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.512	0.488	0.000
M48.24 Kissing spine (Thoracic region)	0.512	0.488	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.512	0.488	0.000
M48.22 Kissing spine (Cervical region)	0.512	0.488	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.512	0.488	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.512	0.488	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.512	0.488	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.512	0.488	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.512	0.488	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.512	0.488	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.512	0.488	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.512	0.488	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.512	0.488	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.512	0.488	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.512	0.488	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.512	0.488	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.512	0.488	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.512	0.488	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.512	0.488	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.512	0.488	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.512	0.488	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.512	0.488	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.512	0.488	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.512	0.488	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.512	0.488	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.512	0.488	0.000
M62.9 Disorder of muscle, unspecified	0.512	0.488	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.512	0.488	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.512	0.488	0.000
M43.04 Spondylolysis (Thoracic region)	0.512	0.488	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.512	0.488	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.512	0.488	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.512	0.488	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.511	0.488	0.000
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.511	0.489	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.511	0.489	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.511	0.489	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.511	0.489	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.511	0.489	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.511	0.489	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.511	0.489	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.511	0.489	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.511	0.489	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.511	0.489	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.511	0.489	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.511	0.489	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.511	0.489	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.511	0.489	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.511	0.489	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.511	0.489	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.511	0.489	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.511	0.489	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.511	0.489	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.511	0.489	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.511	0.489	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.511	0.489	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.511	0.489	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.511	0.489	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.511	0.489	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.511	0.489	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.511	0.489	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.511	0.489	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.511	0.489	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.511	0.489	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.511	0.489	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.511	0.489	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.511	0.489	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.511	0.489	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.511	0.489	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.511	0.489	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.511	0.489	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.511	0.489	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.511	0.489	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.511	0.489	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.511	0.489	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.511	0.489	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.511	0.489	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.511	0.489	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.511	0.489	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.511	0.489	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.511	0.489	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.511	0.489	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.511	0.489	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.511	0.489	0.000
M86 Osteomyelitis	0.511	0.489	0.000
M91-M94 Chondropathies	0.509	0.491	0.001
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)	0.506	0.494	0.000
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)	0.506	0.494	0.000
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)	0.506	0.494	0.000
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)	0.506	0.494	0.000
M12.84 Other specific arthropathies, not elsewhere classified (Hand)	0.506	0.494	0.000
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)	0.506	0.494	0.000
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)	0.506	0.494	0.000
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)	0.506	0.494	0.000
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)	0.506	0.494	0.000
M81.4 Drug-induced osteoporosis	0.506	0.494	0.000
M51.8 Other specified intervertebral disk disorders	0.505	0.495	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.503	0.497	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.501	0.498	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.501	0.499	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.501	0.499	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.501	0.499	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.501	0.499	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.501	0.499	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.501	0.499	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.501	0.499	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.501	0.499	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.501	0.499	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.501	0.499	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.501	0.499	0.000
M67.3 Transient synovitis	0.501	0.499	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.500	0.499	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.500	0.499	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.500	0.499	0.000
M09.0 Juvenile arthritis in psoriasis	0.500	0.499	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.500	0.500	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.499	0.501	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.498	0.502	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.497	0.503	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.497	0.503	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.497	0.503	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.497	0.503	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.497	0.503	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.497	0.503	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.497	0.503	0.000
M54.54 Low back pain-Thoracic	0.495	0.505	0.000
M95.3 Acquired deformity of neck	0.492	0.508	0.000
M99.8 Other biomechanical lesions	0.488	0.511	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.488	0.512	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.488	0.512	0.000
M54.55 Low back pain (Thoracolumbar region)	0.487	0.513	0.000
M54.53 Low back pain-Cervicothoracic	0.487	0.513	0.000
M54.52 Low back pain-Cervical	0.487	0.513	0.000
M54.51 Low back pain-Occipit-atl-axl	0.487	0.513	0.000
M11.2 Other chondrocalcinosis	0.486	0.514	0.000
M62.4 Contracture of muscle	0.486	0.514	0.000
M62.3 Immobility syndrome (paraplegic)	0.486	0.514	0.000
M62.2 Ischaemic infarction of muscle	0.486	0.514	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.485	0.515	0.000
M62.0 Diastasis of muscle	0.484	0.515	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.481	0.519	0.000
M66.4 Spontaneous rupture of other tendons	0.480	0.520	0.000
M14.2 Diabetic arthropathy	0.477	0.523	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.477	0.523	0.000
M07.5 Arthropathy in ulcerative colitis	0.477	0.523	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.477	0.523	0.000
M07.2 Psoriatic spondylitis	0.477	0.523	0.000
M07.1 Arthritis mutilans	0.477	0.523	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.477	0.523	0.000
M87 Osteonecrosis	0.476	0.524	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.473	0.526	0.000
M88.8 Paget's disease of other bones	0.472	0.527	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.472	0.528	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.470	0.530	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.470	0.530	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.470	0.530	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.470	0.530	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.470	0.530	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.470	0.530	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.470	0.530	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.470	0.530	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.470	0.530	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.470	0.530	0.000
M11.1 Familial chondrocalcinosis	0.470	0.530	0.000
M11.0 Hydroxyapatite deposition disease	0.470	0.530	0.000
M10.9 Gout, unspecified	0.468	0.532	0.000
M13.89 Other specified arthritis (Site unspecified)	0.467	0.532	0.000
M13.08 Polyarthritis, unspecified (Other)	0.466	0.534	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.466	0.534	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.466	0.534	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.466	0.534	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.466	0.534	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.466	0.534	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.466	0.534	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.463	0.537	0.000
M12.28 Villonodular synovitis (pigmented) (Other)	0.463	0.537	0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.463	0.537	0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.463	0.537	0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.463	0.537	0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.463	0.537	0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.463	0.537	0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.463	0.537	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.463	0.537	0.000
M90.6 Osteitis deformans in neoplastic disease	0.461	0.539	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.461	0.539	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.461	0.539	0.000
M90.3 Osteonecrosis in caisson disease	0.461	0.539	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.461	0.539	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations