TreeWAS – Variant ID: rs10253361

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H16.0 Corneal ulcer	0.000	0.966	0.034
H16 Keratitis	0.000	0.967	0.033
H20.9 Iridocyclitis, unspecified	0.000	0.968	0.032
H20 Iridocyclitis	0.000	0.968	0.032
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.971	0.029
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.971	0.029
H20.8 Other iridocyclitis	0.000	0.971	0.028
H16.4 Corneal neovascularisation	0.000	0.974	0.026
H16.3 Interstitial and deep keratitis	0.000	0.974	0.026
H16.9 Keratitis, unspecified	0.000	0.975	0.025
H17 Corneal scars and opacities	0.000	0.976	0.024
H20.0 Acute and subacute iridocyclitis	0.000	0.976	0.024
H16.8 Other keratitis	0.000	0.976	0.024
I85.9 Oesophageal varices without bleeding	0.000	0.976	0.024
H15 Disorders of sclera	0.000	0.976	0.024
H20.1 Chronic iridocyclitis	0.000	0.976	0.023
I85.0 Oesophageal varices with bleeding	0.000	0.977	0.023
H20.2 Lens-induced iridocyclitis	0.000	0.977	0.023
S61.1 Open wound of finger(s) with damage to nail	0.022	0.978	0.000
H17.9 Corneal scar and opacity, unspecified	0.000	0.978	0.022
I85 Oesophageal varices	0.000	0.978	0.022
H15.8 Other disorders of sclera	0.000	0.980	0.020
H18 Other disorders of cornea	0.000	0.980	0.020
K76.6 Portal hypertension	0.000	0.980	0.020
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.000	0.980	0.020
S61 Open wound of wrist and hand	0.020	0.980	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.981	0.018
S61.9 Open wound of wrist and hand, part unspecified	0.018	0.982	0.000
S60-S69 Injuries to the wrist and hand	0.018	0.982	0.000
H15.1 Episcleritis	0.000	0.982	0.018
H15.9 Disorder of sclera, unspecified	0.000	0.982	0.018
H17.1 Other central corneal opacity	0.000	0.982	0.018
H17.0 Adherent leukoma	0.000	0.982	0.018
S67 Crushing injury of wrist and hand	0.017	0.983	0.000
H16.2 Keratoconjunctivitis	0.000	0.983	0.017
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.017	0.983	0.000
H18.4 Corneal degeneration	0.000	0.983	0.017
S63.6 Sprain and strain of finger(s)	0.017	0.983	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.016	0.984	0.000
H18.1 Bullous keratopathy	0.000	0.984	0.016
H18.0 Corneal pigmentations and deposits	0.000	0.984	0.016
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.000	0.984	0.016
H18.9 Disorder of cornea, unspecified	0.000	0.984	0.016
S65 Injury of blood vessels at wrist and hand level	0.016	0.984	0.000
S69 Other and unspecified injuries of wrist and hand	0.016	0.984	0.000
H15.0 Scleritis	0.000	0.985	0.015
H18.7 Other corneal deformities	0.000	0.985	0.015
S62 Fracture at wrist and hand level	0.015	0.985	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.985	0.015
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.000	0.986	0.014
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.000	0.986	0.014
S69.9 Unspecified injury of wrist and hand	0.014	0.986	0.000
H17.8 Other corneal scars and opacities	0.000	0.986	0.014
S61.7 Multiple open wounds of wrist and hand	0.014	0.986	0.000
H18.2 Other corneal oedema	0.000	0.986	0.014
S68 Traumatic amputation of wrist and hand	0.014	0.986	0.000
S63.2 Multiple dislocations of fingers	0.014	0.986	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.986	0.013
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.000	0.986	0.013
H18.3 Changes in corneal membranes	0.000	0.987	0.013
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.013	0.987	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.013	0.987	0.000
S62.4 Multiple fractures of metacarpal bones	0.013	0.987	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.000	0.987	0.013
S60 Superficial injury of wrist and hand	0.013	0.987	0.000
S63.0 Dislocation of wrist	0.013	0.987	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.013	0.987	0.000
S62.2 Fracture of first metacarpal bone	0.012	0.988	0.000
S63.1 Dislocation finger	0.012	0.988	0.000
S62.7 Multiple fractures of fingers	0.012	0.988	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.012	0.988	0.000
S65.4 Injury of blood vessel(s) of thumb	0.012	0.988	0.000
S69.8 Other specified injuries of wrist and hand	0.012	0.988	0.000
S65.1 Injury of radial artery at wrist and hand level	0.012	0.988	0.000
S62.1 Fracture of other carpal bone(s)	0.012	0.988	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.000	0.988	0.012
S65.5 Injury of blood vessel(s) of other finger	0.012	0.988	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.012	0.988	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.012	0.988	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.012	0.988	0.000
S63.5 Sprain and strain of wrist	0.012	0.988	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.011	0.988	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.011	0.988	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.011	0.988	0.000
S65.3 Injury of deep palmar arch	0.011	0.988	0.000
S65.2 Injury of superficial palmar arch	0.011	0.988	0.000
S62.6 Fracture of other finger	0.011	0.988	0.000
S60.2 Contusion of other parts of wrist and hand	0.011	0.989	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.000	0.989	0.011
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.011	0.989	0.000
S62.61 Fracture of other finger (open)	0.011	0.989	0.000
S62.3 Fracture of other metacarpal bone	0.011	0.989	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.011	0.989	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.010	0.990	0.000
S61.8 Open wound of other parts of wrist and hand	0.010	0.990	0.000
S64 Injury of nerves at wrist and hand level	0.010	0.990	0.000
H21 Other disorders of iris and ciliary body	0.000	0.990	0.010
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.010	0.990	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.010	0.990	0.000
S68.4 Traumatic amputation of hand at wrist level	0.010	0.990	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.010	0.990	0.000
S69.7 Multiple injuries of wrist and hand	0.010	0.990	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.010	0.990	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.010	0.990	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.010	0.990	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.010	0.990	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.010	0.990	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.010	0.990	0.000
S62.70 Multiple fractures of fingers (closed)	0.010	0.990	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.010	0.990	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.010	0.990	0.000
S62.71 Multiple fractures of fingers (open)	0.010	0.990	0.000
S60.1 Contusion of finger(s) with damage to nail	0.010	0.990	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.009	0.990	0.000
H18.6 Keratoconus	0.000	0.990	0.009
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.009	0.990	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.009	0.990	0.000
K04.8 Radicular cyst	0.000	0.991	0.009
M65 Synovitis and tenosynovitis	0.009	0.991	0.000
S60.0 Contusion of finger(s) without damage to nail	0.009	0.991	0.000
S62.31 Fracture of other metacarpal bone (open)	0.009	0.991	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.009	0.991	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.009	0.991	0.000
S62.21 Fracture of first metacarpal bone (open)	0.009	0.991	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.009	0.991	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.009	0.991	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.009	0.991	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.009	0.991	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.009	0.991	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.008	0.992	0.000
M65.8 Other synovitis and tenosynovitis	0.008	0.992	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.008	0.992	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.008	0.992	0.000
M65.2 Calcific tendinitis	0.008	0.992	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.008	0.992	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.008	0.992	0.000
S64.8 Injury of other nerves at wrist and hand level	0.008	0.992	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.008	0.992	0.000
H21.0 Hyphaema	0.000	0.992	0.008
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.992	0.007
S64.1 Injury of median nerve at wrist and hand level	0.007	0.992	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.007	0.993	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.007	0.993	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.007	0.993	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.007	0.993	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.007	0.993	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.007	0.993	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.007	0.993	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.007	0.993	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.993	0.007
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.007	0.993	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.993	0.007
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.007	0.993	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.007	0.993	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.007	0.993	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.007	0.993	0.000
K76 Other diseases of liver	0.000	0.993	0.007
S61.0 Open wound of finger(s) without damage to nail	0.007	0.993	0.000
K70 Alcoholic liver disease	0.000	0.993	0.007
S60.9 Superficial injury of wrist and hand, unspecified	0.007	0.993	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.007	0.993	0.000
E14.3 With ophthalmic complications	0.007	0.993	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.993	0.007
H21.4 Pupillary membranes	0.000	0.993	0.007
S64.3 Injury of digital nerve of thumb	0.007	0.993	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.007	0.993	0.000
H21.2 Degeneration of iris and ciliary body	0.000	0.993	0.007
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.993	0.006
K74 Fibrosis and cirrhosis of liver	0.000	0.993	0.007
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.993	0.006
K74.5 Biliary cirrhosis, unspecified	0.000	0.993	0.007
M65.0 Abscess of tendon sheath	0.006	0.993	0.000
K76.7 Hepatorenal syndrome	0.000	0.994	0.006
E83.4 Disorders of magnesium metabolism	0.000	0.994	0.006
S62.5 Fracture of thumb	0.006	0.994	0.000
H18.8 Other specified disorders of cornea	0.001	0.994	0.006
S60.8 Other superficial injuries of wrist and hand	0.006	0.994	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.006	0.994	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.006	0.994	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.006	0.994	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.006	0.994	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.006	0.994	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.006	0.994	0.000
M65.1 Other infective (teno)synovitis	0.006	0.994	0.000
K70.4 Alcoholic hepatic failure	0.000	0.994	0.006
H21.8 Other specified disorders of iris and ciliary body	0.000	0.994	0.006
Z57.5 Occupational exposure to toxic agents in other industries	0.006	0.994	0.000
M65.29 Calcific tendinitis (Site unspecified)	0.006	0.994	0.000
M65.28 Calcific tendinitis (Other)	0.006	0.994	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.006	0.994	0.000
M65.26 Calcific tendinitis (Lower leg)	0.006	0.994	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.006	0.994	0.000
M65.24 Calcific tendinitis (Hand)	0.006	0.994	0.000
M65.23 Calcific tendinitis (Forearm)	0.006	0.994	0.000
M65.22 Calcific tendinitis (Upper arm)	0.006	0.994	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.006	0.994	0.000
J38.3 Other diseases of vocal cords	0.000	0.994	0.006
K70-K77 Diseases of liver	0.000	0.994	0.006
K74.6 Other and unspecified cirrhosis of liver	0.000	0.994	0.006
K74.3 Primary biliary cirrhosis	0.000	0.994	0.006
K70.0 Alcoholic fatty liver	0.000	0.994	0.006
S06.6 Traumatic subarachnoid haemorrhage	0.005	0.994	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.995	0.005
K76.4 Peliosis hepatis	0.000	0.995	0.005
K76.3 Infarction of liver	0.000	0.995	0.005
K76.2 Central haemorrhagic necrosis of liver	0.000	0.995	0.005
M65.84 Other synovitis and tenosynovitis (Hand)	0.005	0.995	0.000
K76.1 Chronic passive congestion of liver	0.000	0.995	0.005
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.995	0.005
S62.30 Fracture of other metacarpal bone (closed)	0.005	0.995	0.000
K74.0 Hepatic fibrosis	0.000	0.995	0.005
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.005	0.995	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.995	0.005
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.995	0.005
M65.09 Abscess of tendon sheath (Site unspecified)	0.005	0.995	0.000
M65.08 Abscess of tendon sheath (Other)	0.005	0.995	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.005	0.995	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.005	0.995	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.005	0.995	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.005	0.995	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.005	0.995	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.005	0.995	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.005	0.995	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.005	0.995	0.000
K74.1 Hepatic sclerosis	0.000	0.995	0.005
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.005	0.995	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.995	0.005
M65.19 Other infective (teno)synovitis (Site unspecified)	0.004	0.995	0.000
M65.18 Other infective (teno)synovitis (Other)	0.004	0.995	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.004	0.995	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.004	0.995	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.004	0.995	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.004	0.995	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.004	0.995	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.004	0.995	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.004	0.995	0.000
M65.3 Trigger finger	0.005	0.995	0.000
M65.04 Abscess of tendon sheath (Hand)	0.004	0.995	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.996	0.004
Y40.8 Other systemic antibiotics	0.000	0.996	0.004
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.004	0.996	0.000
Y40 Systemic antibiotics	0.000	0.996	0.004
Y44.2 Anticoagulants	0.000	0.996	0.004
K71 Toxic liver disease	0.000	0.996	0.004
Y40.3 Macrolides	0.000	0.996	0.004
K77 Liver disorders in diseases classified elsewhere	0.000	0.996	0.004
M65.14 Other infective (teno)synovitis (Hand)	0.004	0.996	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.996	0.004
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.996	0.004
Y40.7 Antifungal antibiotics, systemically used	0.000	0.996	0.004
M65.39 Trigger finger-Site unspec	0.004	0.996	0.000
C50.1 Central portion of breast	0.004	0.996	0.000
S62.51 Fracture of thumb (open)	0.003	0.996	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.996	0.004
Y40.4 Tetracyclines	0.000	0.996	0.004
K73 Chronic hepatitis, not elsewhere classified	0.000	0.996	0.004
S86 Injury of muscle and tendon at lower leg level	0.004	0.996	0.000
M65.38 Trigger finger-Other	0.003	0.996	0.000
M65.37 Trigger finger-Ankle/foot	0.003	0.996	0.000
M65.36 Trigger finger-Lower leg	0.003	0.996	0.000
M65.35 Trigger finger-Pelvic/thigh	0.003	0.996	0.000
M65.33 Trigger finger-Forearm	0.003	0.996	0.000
M65.32 Trigger finger-Upper arm	0.003	0.996	0.000
M65.31 Trigger finger-Shldr region	0.003	0.996	0.000
M65.30 Trigger finger-Mult sites	0.003	0.996	0.000
K70.1 Alcoholic hepatitis	0.000	0.996	0.003
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.997	0.003
K76.8 Other specified diseases of liver	0.000	0.997	0.003
D21.0 Connective and other soft tissue of head, face and neck	0.003	0.997	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.003	0.997	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.000	0.997	0.003
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.997	0.003
Y40.2 Chloramphenicol group	0.000	0.997	0.003
S66 Injury of muscle and tendon at wrist and hand level	0.003	0.997	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.997	0.003
K71.8 Toxic liver disease with other disorders of liver	0.000	0.997	0.003
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.997	0.003
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.997	0.003
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.997	0.003
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.997	0.003
K71.2 Toxic liver disease with acute hepatitis	0.000	0.997	0.003
I82 Other venous embolism and thrombosis	0.000	0.997	0.003
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.997	0.003
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.997	0.003
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.997	0.003
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.997	0.003
K71.9 Toxic liver disease, unspecified	0.000	0.997	0.003
Y40.6 Rifamycins	0.000	0.997	0.003
Y44 Agents primarily affecting blood constituents	0.000	0.997	0.003
Z57.3 Occupational exposure to other air contaminants	0.003	0.997	0.000
Z57 Occupational exposure to risk-factors	0.003	0.997	0.000
K71.0 Toxic liver disease with cholestasis	0.000	0.997	0.003
L71.9 Rosacea, unspecified	0.000	0.997	0.003
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.997	0.003
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.997	0.003
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.997	0.003
S86.0 Injury of Achilles tendon	0.003	0.997	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.003	0.997	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.997	0.003
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.997	0.003
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
I80 Phlebitis and thrombophlebitis	0.000	0.997	0.003
M65-M68 Disorders of synovium and tendon	0.003	0.997	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.003	0.997	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.003
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.997	0.002
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.997	0.003
S06.4 Epidural haemorrhage	0.003	0.997	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
Y44.5 Thrombolytic drugs	0.000	0.997	0.003
G47.9 Sleep disorder, unspecified	0.000	0.997	0.003
I35.0 Aortic (valve) stenosis	0.000	0.997	0.003
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
I83 Varicose veins of lower extremities	0.000	0.997	0.003
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.002	0.997	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.002	0.997	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.003
X62.9 Unspecified place	0.000	0.997	0.003
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.997	0.003
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.003	0.997	0.000
I82.2 Embolism and thrombosis of vena cava	0.000	0.997	0.003
N97.9 Female infertility, unspecified	0.003	0.997	0.000
R18 Ascites	0.000	0.997	0.003
I82.1 Thrombophlebitis migrans	0.000	0.997	0.002
N99.2 Postprocedural adhesions of vagina	0.003	0.997	0.000
K73.9 Chronic hepatitis, unspecified	0.000	0.997	0.002
S29.9 Unspecified injury of thorax	0.003	0.997	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.997	0.000
S62.50 Fracture of thumb (closed)	0.002	0.997	0.000
S64.4 Injury of digital nerve of other finger	0.002	0.998	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.998	0.002
I86.4 Gastric varices	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.002	0.998	0.000
I82.0 Budd-Chiari syndrome	0.000	0.998	0.002
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.998	0.002
Y44.7 Plasma substitutes	0.000	0.998	0.002
Y44.6 Natural blood and blood products	0.000	0.998	0.002
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.998	0.002
Z57.9 Occupational exposure to unspecified risk-factor	0.002	0.998	0.000
Z57.7 Occupational exposure to vibration	0.002	0.998	0.000
Z57.6 Occupational exposure to extreme temperature	0.002	0.998	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.002	0.998	0.000
Z57.1 Occupational exposure to radiation	0.002	0.998	0.000
Z57.0 Occupational exposure to noise	0.002	0.998	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.998	0.002
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.998	0.002
K72.1 Chronic hepatic failure	0.000	0.998	0.002
H53.2 Diplopia	0.002	0.998	0.000
I86 Varicose veins of other sites	0.000	0.998	0.002
H92.0 Otalgia	0.000	0.998	0.002
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.002	0.998	0.000
S86.00 Unspecified injury of Achilles tendon	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
L40.5 Arthropathic psoriasis	0.000	0.998	0.002
M67.2 Synovial hypertrophy, not elsewhere classified	0.002	0.998	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.998	0.002
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
I86.8 Varicose veins of other specified sites	0.000	0.998	0.002
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.998	0.002
I81 Portal vein thrombosis	0.000	0.998	0.002
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
E83.1 Disorders of iron metabolism	0.000	0.998	0.002
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.998	0.002
Y42.7 Androgens and anabolic congeners	0.000	0.998	0.002
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
K04.7 Periapical abscess without sinus	0.000	0.998	0.002
R70.0 Elevated erythrocyte sedimentation rate	0.002	0.998	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
H47.3 Other disorders of optic disk	0.000	0.998	0.002
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.998	0.002
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.998	0.002
K75 Other inflammatory liver diseases	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.998	0.002
F52.2 Failure of genital response	0.002	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.998	0.002
I82.3 Embolism and thrombosis of renal vein	0.000	0.998	0.002
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.998	0.002
Y59.0 Viral vaccines	0.000	0.998	0.002
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
I86.3 Vulval varices	0.000	0.998	0.002
Y59.3 Immunoglobulin	0.000	0.998	0.002
Y48 Anaesthetics and therapeutic gases	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.000	0.998	0.002
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
M47.86 Other spondylosis (Lumbar region)	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.998	0.002
C56 Malignant neoplasm of ovary	0.000	0.998	0.002
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
I86.0 Sublingual varices	0.000	0.998	0.002
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
K04 Diseases of pulp and periapical tissues	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.000	0.998	0.002
Y41.0 Sulphonamides	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
E83 Disorders of mineral metabolism	0.000	0.998	0.002
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
S62.60 Fracture of other finger (closed)	0.002	0.998	0.000
A07.1 Giardiasis [lambliasis]	0.000	0.998	0.002
Y48.3 Local anaesthetics	0.000	0.998	0.002
M77.02 Medial epicondylitis (Upper arm)	0.000	0.998	0.002
E66.8 Other obesity	0.002	0.998	0.000
R25.2 Cramp and spasm	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.000	0.998	0.002
Y53.6 Antidiarrhoeal drugs	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
L52 Erythema nodosum	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.002	0.998	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
Y53.4 Other laxatives	0.000	0.998	0.002
E23.0 Hypopituitarism	0.000	0.998	0.002
E89.2 Postprocedural hypoparathyroidism	0.000	0.998	0.002
F22.0 Delusional disorder	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.000	0.998	0.002
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.000	0.998	0.002
K37 Unspecified appendicitis	0.000	0.998	0.002
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.002	0.998	0.000
K13.0 Diseases of lips	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
Y41.4 Anthelminthics	0.000	0.998	0.002
Y41.3 Other antiprotozoal drugs	0.000	0.998	0.002
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
Y53.7 Emetics	0.000	0.998	0.002
Y53.5 Digestants	0.000	0.998	0.002
Y53.3 Saline and osmotic laxatives	0.000	0.998	0.002
Y53.0 Histamine H2-receptor antagonists	0.000	0.998	0.002
Y59.9 Vaccine or biological substance, unspecified	0.000	0.998	0.002
Y59.8 Other specified vaccines and biological substances	0.000	0.998	0.002
Y59.2 Protozoal vaccines	0.000	0.998	0.002
Y59.1 Rickettsial vaccines	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
M67.4 Ganglion	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
H92.1 Otorrhoea	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.998	0.000
M67.3 Transient synovitis	0.002	0.998	0.000
R40.2 Coma, unspecified	0.000	0.998	0.002
Y54.4 Loop [high-ceiling] diuretics	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.998	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.998	0.002
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
Y49.9 Psychotropic drug, unspecified	0.000	0.998	0.002
Y49.7 Psychostimulants with abuse potential	0.000	0.998	0.002
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.998	0.002
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
B02.9 Zoster without complication	0.002	0.998	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.000	0.998	0.002
Y48.1 Parenteral anaesthetics	0.000	0.998	0.002
Y48.0 Inhaled anaesthetics	0.000	0.998	0.002
I88 Nonspecific lymphadenitis	0.000	0.998	0.001
D21 Other benign neoplasms of connective and other soft tissue	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.001	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.998	0.000
K04.3 Abnormal hard tissue formation in pulp	0.000	0.998	0.002
K04.2 Pulp degeneration	0.000	0.998	0.002
K04.1 Necrosis of pulp	0.000	0.998	0.002
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.002
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.002
Y54.0 Mineralocorticoids	0.000	0.998	0.002
Y58 Bacterial vaccines	0.000	0.998	0.002
E83.8 Other disorders of mineral metabolism	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations