TreeWAS – Variant ID: rs10262453

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N60.1 Diffuse cystic mastopathy	0.397	0.603	0.000
M24.2 Disorder of ligament	0.039	0.961	0.000
M24.24 Disorder of ligament (Hand)	0.038	0.962	0.000
M24.26 Disorder of ligament (Lower leg)	0.034	0.966	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.033	0.967	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.032	0.968	0.000
M24.21 Disorder of ligament (Shoulder region)	0.031	0.969	0.000
M24.23 Disorder of ligament (Forearm)	0.031	0.969	0.000
M24.28 Disorder of ligament (Other)	0.031	0.969	0.000
M24.29 Disorder of ligament (Site unspecified)	0.028	0.972	0.000
M24.22 Disorder of ligament (Upper arm)	0.028	0.972	0.000
M24.20 Disorder of ligament (Multiple sites)	0.028	0.972	0.000
M24 Other specific joint derangements	0.023	0.977	0.000
M24.1 Other articular cartilage disorders	0.022	0.978	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.020	0.980	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.020	0.980	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.980	0.020
M24.7 Protrusio acetabuli	0.018	0.982	0.000
M24.5 Contracture of joint	0.018	0.982	0.000
N60 Benign mammary dysplasia	0.017	0.983	0.000
M24.6 Ankylosis of joint	0.017	0.983	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.017	0.983	0.000
M24.9 Joint derangement, unspecified	0.016	0.983	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.016	0.984	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.016	0.984	0.000
M24.18 Other articular cartilage disorders (Other)	0.016	0.984	0.000
M24.14 Other articular cartilage disorders (Hand)	0.016	0.984	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.016	0.984	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.016	0.984	0.000
M24.52 Contracture of joint (Upper arm)	0.016	0.984	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.016	0.984	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.015	0.985	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.985	0.015
M24.13 Other articular cartilage disorders (Forearm)	0.015	0.985	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.985	0.015
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.985	0.015
N60.9 Benign mammary dysplasia, unspecified	0.015	0.985	0.000
M24.51 Contracture of joint (Shoulder region)	0.015	0.985	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.015	0.985	0.000
M24.79 Protrusio acetabuli-Site unspec	0.013	0.987	0.000
M24.78 Protrusio acetabuli-Other	0.013	0.987	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.013	0.987	0.000
M24.76 Protrusio acetabuli-Lower leg	0.013	0.987	0.000
M24.74 Protrusio acetabuli-Hand	0.013	0.987	0.000
M24.73 Protrusio acetabuli-Forearm	0.013	0.987	0.000
M24.72 Protrusio acetabuli-Upper arm	0.013	0.987	0.000
M24.71 Protrusio acetabuli-Shldr region	0.013	0.987	0.000
M24.70 Protrusio acetabuli-Mult sites	0.013	0.987	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.987	0.013
M24.4 Recurrent dislocation and subluxation of joint	0.013	0.987	0.000
M24.59 Contracture of joint (Site unspecified)	0.013	0.987	0.000
M24.58 Contracture of joint (Other)	0.013	0.987	0.000
M24.53 Contracture of joint (Forearm)	0.013	0.987	0.000
M24.50 Contracture of joint (Multiple sites)	0.013	0.987	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.012	0.987	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.012	0.987	0.000
I74 Arterial embolism and thrombosis	0.000	0.987	0.013
I74.5 Embolism and thrombosis of iliac artery	0.000	0.987	0.013
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.987	0.012
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.012	0.988	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.012	0.988	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.012	0.988	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.012	0.988	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.012	0.988	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.012	0.988	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.012	0.988	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.012	0.988	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.012	0.988	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.012	0.988	0.000
M24.68 Ankylosis of joint (Other)	0.012	0.988	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.012	0.988	0.000
M24.64 Ankylosis of joint (Hand)	0.012	0.988	0.000
M24.63 Ankylosis of joint (Forearm)	0.012	0.988	0.000
M24.62 Ankylosis of joint (Upper arm)	0.012	0.988	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.012	0.988	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.012	0.988	0.000
M24.66 Ankylosis of joint (Lower leg)	0.012	0.988	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.012	0.988	0.000
M24.98 Joint derangement, unspecified (Other)	0.012	0.988	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.012	0.988	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.012	0.988	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.012	0.988	0.000
M24.94 Joint derangement, unspecified (Hand)	0.012	0.988	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.012	0.988	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.012	0.988	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.012	0.988	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.012	0.988	0.000
M24.0 Loose body in joint	0.012	0.988	0.000
M24.57 Contracture of joint (Ankle and foot)	0.012	0.988	0.000
N60.8 Other benign mammary dysplasias	0.011	0.989	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.989	0.011
M24.54 Contracture of joint (Hand)	0.011	0.989	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.011	0.989	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.011	0.989	0.000
M24.56 Contracture of joint (Lower leg)	0.011	0.989	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.010	0.990	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.990	0.010
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.990	0.010
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.010	0.990	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.010	0.990	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.010	0.990	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.010	0.990	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.010	0.990	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.010	0.990	0.000
R22.0 Localised swelling, mass and lump, head	0.000	0.990	0.010
M24.03 Loose body in joint (Forearm)	0.010	0.990	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.009	0.990	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.009	0.991	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.991	0.009
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.991	0.009
M24.09 Loose body in joint (Site unspecified)	0.009	0.991	0.000
M24.08 Loose body in joint (Other)	0.009	0.991	0.000
M24.06 Loose body in joint-Lower leg	0.009	0.991	0.000
M24.00 Loose body in joint (Multiple sites)	0.009	0.991	0.000
N60.3 Fibrosclerosis of breast	0.009	0.991	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.008	0.992	0.000
R22.1 Localised swelling, mass and lump, neck	0.000	0.992	0.008
L29.0 Pruritus ani	0.000	0.992	0.008
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.992	0.008
M24.04 Loose body in joint (Hand)	0.008	0.992	0.000
M24.07 Loose body in joint (Ankle and foot)	0.008	0.992	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.008	0.992	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.008	0.992	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.008	0.992	0.000
N60.0 Solitary cyst of breast	0.008	0.992	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.007	0.992	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.007	0.992	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.992	0.007
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.007	0.993	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.007	0.993	0.000
M24.02 Loose body in joint (Upper arm)	0.007	0.993	0.000
Y84.0 Cardiac catheterisation	0.007	0.993	0.000
M79.62 Pain in limb (Upper arm)	0.000	0.994	0.006
M24.01 Loose body in joint (Shoulder region)	0.006	0.994	0.000
S92.30 Fracture of metatarsal bone (closed)	0.006	0.994	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.006	0.994	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.006	0.994	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.995	0.001
F32.0 Mild depressive episode	0.005	0.995	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.996	0.004
K31.9 Disease of stomach and duodenum, unspecified	0.004	0.996	0.000
D61.9 Aplastic anaemia, unspecified	0.004	0.996	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.000	0.996	0.004
N60.2 Fibroadenosis of breast	0.004	0.996	0.000
G56.8 Other mononeuropathies of upper limb	0.004	0.996	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.004	0.996	0.000
M46.4 Discitis, unspecified	0.004	0.996	0.000
H53.1 Subjective visual disturbances	0.004	0.996	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.003	0.997	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.003	0.997	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.003	0.997	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.003	0.997	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.003	0.997	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.003	0.997	0.000
N60.4 Mammary duct ectasia	0.002	0.997	0.001
M46.44 Discitis, unspecified (Thoracic region)	0.003	0.997	0.000
H26.8 Other specified cataract	0.003	0.997	0.000
M46 Other inflammatory spondylopathies	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M46.42 Discitis, unspecified (Cervical region)	0.003	0.997	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
R13 Dysphagia	0.000	0.997	0.003
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.003	0.997	0.000
B17.1 Acute hepatitis C	0.003	0.997	0.000
M11.2 Other chondrocalcinosis	0.000	0.997	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.997	0.000
Q63.0 Accessory kidney	0.003	0.997	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.002	0.997	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.002	0.997	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.002	0.997	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.997	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.003	0.997	0.000
S71.1 Open wound of thigh	0.000	0.997	0.003
M46.1 Sacro-iliitis, not elsewhere classified	0.002	0.997	0.000
F34.1 Dysthymia	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
I77.6 Arteritis, unspecified	0.002	0.998	0.000
M46.2 Osteomyelitis of vertebra	0.002	0.998	0.000
M46.0 Spinal enthesopathy	0.002	0.998	0.000
M46.8 Other specified inflammatory spondylopathies	0.002	0.998	0.000
M46.5 Other infective spondylopathies	0.002	0.998	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.998	0.000
L29 Pruritus	0.000	0.998	0.002
I77.2 Rupture of artery	0.002	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.998	0.002
I77.0 Arteriovenous fistula, acquired	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.998	0.002
T88.4 Failed or difficult intubation	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.998	0.002
M11.28 Other chondrocalcinosis (Other)	0.000	0.998	0.002
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.998	0.002
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.998	0.002
M11.24 Other chondrocalcinosis (Hand)	0.000	0.998	0.002
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.998	0.002
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.998	0.002
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.998	0.002
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.998	0.002
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.002	0.998	0.000
I77.3 Arterial fibromuscular dysplasia	0.002	0.998	0.000
L29.2 Pruritus vulvae	0.000	0.998	0.002
I77 Other disorders of arteries and arterioles	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.998	0.002
M25.74 Osteophyte (Hand)	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.002	0.998	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.002	0.998	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.002	0.998	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.002	0.998	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.002	0.998	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.002	0.998	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.002	0.998	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.002	0.998	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.002	0.998	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.000	0.998	0.002
M46.06 Spinal enthesopathy (Lumbar region)	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
R10.2 Pelvic and perineal pain	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.002	0.998	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.002	0.998	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.002	0.998	0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.002	0.998	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.002	0.998	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.002	0.998	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.002	0.998	0.000
N80.3 Endometriosis of pelvic peritoneum	0.002	0.998	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.002	0.998	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.002	0.998	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.002	0.998	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.002	0.998	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.002	0.998	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.002	0.998	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.002	0.998	0.000
L60.2 Onychogryphosis	0.002	0.998	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.002	0.998	0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.57 Other infective spondylopathies (Lumbosacral region)	0.002	0.998	0.000
M46.56 Other infective spondylopathies (Lumbar region)	0.002	0.998	0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.002	0.998	0.000
M46.54 Other infective spondylopathies (Thoracic region)	0.002	0.998	0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.002	0.998	0.000
M46.52 Other infective spondylopathies (Cervical region)	0.002	0.998	0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.002	0.998	0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.002	0.998	0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.002	0.998	0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.002	0.998	0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.002	0.998	0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.002	0.998	0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.002	0.998	0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.002	0.998	0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.002	0.998	0.000
L29.1 Pruritus scroti	0.000	0.998	0.002
S71 Open wound of hip and thigh	0.000	0.998	0.002
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.002	0.998	0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.002	0.998	0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.002	0.998	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.002	0.998	0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.002	0.998	0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.002	0.998	0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.002	0.998	0.000
M79.64 Pain in limb (Hand)	0.000	0.998	0.002
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
G47.8 Other sleep disorders	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
T93 Sequelae of injuries of lower limb	0.000	0.998	0.002
I77.5 Necrosis of artery	0.002	0.998	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
S30.1 Contusion of abdominal wall	0.000	0.998	0.002
S71.0 Open wound of hip	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
C18.3 Hepatic flexure	0.002	0.998	0.000
F32.1 Moderate depressive episode	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Y65.4 Failure to introduce or to remove other tube or instrument	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.000	0.998	0.002
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
S70.1 Contusion of thigh	0.000	0.998	0.002
T45.5 Anticoagulants	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
B17 Other acute viral hepatitis	0.002	0.998	0.000
D61 Other aplastic anaemias	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
F34 Persistent mood [affective] disorders	0.002	0.998	0.000
F32 Depressive episode	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
D18.1 Lymphangioma, any site	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Z39.2 Routine postpartum follow-up	0.000	0.998	0.002
L29.3 Anogenital pruritus, unspecified	0.000	0.998	0.001
T42.3 Barbiturates	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.000	0.998	0.002
S71.7 Multiple open wounds of of hip and thigh	0.000	0.998	0.002
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
S79.9 Unspecified injury of hip and thigh	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
Q63.2 Ectopic kidney	0.001	0.998	0.000
S70.8 Other superficial injuries of hip and thigh	0.000	0.998	0.002
T36.4 Tetracyclines	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
I44.2 Atrioventricular block, complete	0.000	0.998	0.002
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
B17.2 Acute hepatitis E	0.001	0.998	0.000
H27.1 Dislocation of lens	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.998	0.002
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.998	0.001
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.998	0.001
Z31.2 In vitro fertilisation	0.000	0.998	0.002
Z76.9 Persons encountering health services in unspecified circumstances	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
M71.38 Other bursal cyst (Other)	0.000	0.998	0.002
I35.0 Aortic (valve) stenosis	0.000	0.998	0.002
T36.3 Macrolides	0.001	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
T49.9 Topical agent, unspecified	0.001	0.998	0.000
T49.8 Other topical agents	0.001	0.998	0.000
T49.7 Dental drugs, topically applied	0.001	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.998	0.000
T49.2 Local astringents and local detergents	0.001	0.998	0.000
T49.1 Antipruritics	0.001	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.002	0.998	0.000
B17.9 Acute viral hepatitis, unspecified	0.001	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
J35.1 Hypertrophy of tonsils	0.000	0.998	0.002
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.000	0.998	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
Q66.0 Talipes equinovarus	0.001	0.998	0.000
S70 Superficial injury of hip and thigh	0.000	0.998	0.002
B17.8 Other specified acute viral hepatitis	0.001	0.998	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.001	0.998	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.998	0.002
D61.8 Other specified aplastic anaemias	0.001	0.998	0.000
D61.3 Idiopathic aplastic anaemia	0.001	0.998	0.000
D61.2 Aplastic anaemia due to other external agents	0.001	0.998	0.000
D61.1 Drug-induced aplastic anaemia	0.001	0.998	0.000
F32.8 Other depressive episodes	0.001	0.998	0.000
M31.6 Other giant cell arteritis	0.000	0.998	0.002
T14.0 Superficial injury of unspecified body region	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.001	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
D23.5 Skin of trunk	0.000	0.998	0.002
F34.9 Persistent mood [affective] disorder, unspecified	0.001	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.001	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.001	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
T46.7 Peripheral vasodilators	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
T93.1 Sequelae of fracture of femur	0.000	0.998	0.001
Q05 Spina bifida	0.001	0.998	0.000
Y65 Other misadventures during surgical and medical care	0.001	0.998	0.000
S92.10 Fracture of talus (closed)	0.001	0.998	0.000
F34.0 Cyclothymia	0.001	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.998	0.001
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.001	0.998	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.998	0.001
T47.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
T36.8 Other systemic antibiotics	0.001	0.999	0.000
T36.7 Antifungal antibiotics, systemically used	0.001	0.999	0.000
T36.6 Rifamycins	0.001	0.999	0.000
T36.5 Aminoglycosides	0.001	0.999	0.000
T36.2 Chloramphenicol group	0.001	0.999	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.001	0.999	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
S79 Other and unspecified injuries of hip and thigh	0.000	0.999	0.001
M07.34 Other psoriatic arthropathies (Hand)	0.001	0.999	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.001	0.999	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.001	0.999	0.000
F10.4 Withdrawal state with delirium	0.001	0.999	0.000
J31.2 Chronic pharyngitis	0.001	0.999	0.000
L29.8 Other pruritus	0.000	0.999	0.001
M79.6 Pain in limb	0.000	0.999	0.001
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.999	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.999	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
T44.0 Anticholinesterase agents	0.001	0.999	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.001	0.999	0.000
T45.8 Other primarily systemic and haematological agents	0.001	0.999	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.999	0.000
T45.6 Fibrinolysis-affecting drugs	0.001	0.999	0.000
T45.4 Iron and its compounds	0.001	0.999	0.000
T45.3 Enzymes, not elsewhere classified	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.001	0.999	0.000
M31 Other necrotising vasculopathies	0.000	0.999	0.001
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.001	0.999	0.000
M79.63 Pain in limb (Forearm)	0.000	0.999	0.001
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.001	0.999	0.000
C16.0 Cardia	0.000	0.999	0.001
I77.8 Other specified disorders of arteries and arterioles	0.001	0.999	0.000
K85.9 Acute pancreatitis, unspecified	0.001	0.999	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.999	0.001
N94.1 Dyspareunia	0.001	0.999	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
M11 Other crystal arthropathies	0.000	0.999	0.001
G47.2 Disorders of the sleep-wake schedule	0.001	0.999	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.001	0.999	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.001	0.999	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.001	0.999	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.001	0.999	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.001	0.999	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.001	0.999	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
T47.7 Emetics	0.001	0.999	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.999	0.000
T47.5 Digestants	0.001	0.999	0.000
T47.4 Other laxatives	0.001	0.999	0.000
T47.3 Saline and osmotic laxatives	0.001	0.999	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.999	0.000
M79.68 Pain in limb (Other)	0.000	0.999	0.001
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.001	0.999	0.000
Q24.8 Other specified congenital malformations of heart	0.000	0.999	0.001
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.999	0.001
D61.0 Constitutional aplastic anaemia	0.001	0.999	0.000
M07.3 Other psoriatic arthropathies	0.001	0.999	0.000
N94.4 Primary dysmenorrhoea	0.001	0.999	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.999	0.000
T41.5 Therapeutic gases	0.001	0.999	0.000
T41.4 Anaesthetic, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations