TreeWAS – Variant ID: rs10270805

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.043	0.957	0.000
S81 Open wound of lower leg	0.033	0.967	0.000
S80-S89 Injuries to the knee and lower leg	0.033	0.967	0.000
S82 Fracture of lower leg, including ankle	0.032	0.968	0.000
S81.8 Open wound of other parts of lower leg	0.031	0.969	0.000
Z47 Other orthopaedic follow-up care	0.030	0.970	0.000
S80 Superficial injury of lower leg	0.030	0.970	0.000
S86 Injury of muscle and tendon at lower leg level	0.029	0.970	0.000
Z47.8 Other specified orthopaedic follow-up care	0.029	0.971	0.000
S81.9 Open wound of lower leg, part unspecified	0.029	0.971	0.000
S82.2 Fracture of shaft of tibia	0.029	0.971	0.000
S81.0 Open wound of knee	0.029	0.971	0.000
S82.6 Fracture of lateral malleolus	0.027	0.973	0.000
S82.0 Fracture of patella	0.027	0.973	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.026	0.974	0.000
S80.8 Other superficial injuries of lower leg	0.025	0.975	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.025	0.975	0.000
S82.7 Multiple fractures of lower leg	0.025	0.975	0.000
S82.21 Fracture of shaft of tibia (open)	0.025	0.975	0.000
S82.20 Fracture of shaft of tibia (closed)	0.025	0.975	0.000
S82.5 Fracture of medial malleolus	0.025	0.975	0.000
S87 Crushing injury of lower leg	0.024	0.976	0.000
S82.4 Fracture of fibula alone	0.024	0.976	0.000
S82.60 Fracture of lateral malleolus (closed)	0.024	0.976	0.000
S80.9 Superficial injury of lower leg, unspecified	0.024	0.976	0.000
S81.7 Multiple open wounds of lower leg	0.024	0.976	0.000
S82.3 Fracture of lower end of tibia	0.024	0.976	0.000
S80.0 Contusion of knee	0.024	0.976	0.000
S88 Traumatic amputation of lower leg	0.023	0.976	0.000
S85 Injury of blood vessels at lower leg level	0.023	0.977	0.000
S82.9 Fracture of lower leg, part unspecified	0.023	0.977	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.023	0.977	0.000
S84 Injury of nerves at lower leg level	0.023	0.977	0.000
S82.00 Fracture of patella (closed)	0.023	0.977	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.023	0.977	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.023	0.977	0.000
S82.01 Fracture of patella (open)	0.021	0.978	0.000
S86.0 Injury of Achilles tendon	0.021	0.979	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.021	0.979	0.000
S82.1 Fracture of upper end of tibia	0.021	0.979	0.000
S89 Other and unspecified injuries of lower leg	0.020	0.979	0.000
S82.61 Fracture of lateral malleolus (open)	0.020	0.979	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.020	0.979	0.000
S82.70 Multiple fractures of lower leg (closed)	0.020	0.980	0.000
S80.7 Multiple superficial injuries of lower leg	0.020	0.980	0.000
S82.51 Fracture of medial malleolus (open)	0.020	0.980	0.000
S82.31 Fracture of lower end of tibia (open)	0.020	0.980	0.000
Z47.9 Orthopaedic follow-up care, unspecified	0.019	0.981	0.000
S82.40 Fracture of fibula alone (closed)	0.019	0.981	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.018	0.981	0.000
S82.71 Multiple fractures of lower leg (open)	0.018	0.982	0.000
S82.8 Fractures of other parts of lower leg	0.018	0.982	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.018	0.982	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.018	0.982	0.000
S87.0 Crushing injury of knee	0.018	0.982	0.000
S82.41 Fracture of fibula alone (open)	0.018	0.982	0.000
S82.50 Fracture of medial malleolus (closed)	0.018	0.982	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.017	0.983	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.017	0.983	0.000
S88.0 Traumatic amputation at knee level	0.017	0.983	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.017	0.983	0.000
S85.8 Injury of other blood vessels at lower leg level	0.017	0.983	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.017	0.983	0.000
S85.5 Injury of popliteal vein	0.017	0.983	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.017	0.983	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.017	0.983	0.000
S85.2 Injury of peroneal artery	0.017	0.983	0.000
S85.0 Injury of popliteal artery	0.017	0.983	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.017	0.983	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.017	0.983	0.000
S84.8 Injury of other nerves at lower leg level	0.017	0.983	0.000
S84.7 Injury of multiple nerves at lower leg level	0.017	0.983	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.017	0.983	0.000
S84.0 Injury of tibial nerve at lower leg level	0.017	0.983	0.000
S82.11 Fracture of upper end of tibia (open)	0.016	0.983	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.016	0.983	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.016	0.984	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
S86.00 Unspecified injury of Achilles tendon	0.015	0.984	0.000
S89.7 Multiple injuries of lower leg	0.015	0.985	0.000
S89.1 Other specified injuries of lower leg	0.015	0.985	0.000
S89.0 Multiple injuries of lower leg	0.015	0.985	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.015	0.985	0.000
S89.8 Other specified injuries of lower leg	0.014	0.986	0.000
S82.30 Fracture of lower end of tibia (closed)	0.014	0.986	0.000
S82.81 Fractures of other parts of lower leg (open)	0.014	0.986	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.014	0.986	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.014	0.986	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.014	0.986	0.000
S82.86 Maisonneuve's fracture	0.013	0.987	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.013	0.987	0.000
S83.3 Tear of articular cartilage of knee, current	0.013	0.987	0.000
S83.1 Dislocation of knee	0.013	0.987	0.000
S83.0 Dislocation of patella	0.013	0.987	0.000
S89.9 Unspecified injury of lower leg	0.013	0.987	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.013	0.987	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.013	0.987	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.012	0.988	0.000
S83.7 Injury to multiple structures of knee	0.012	0.988	0.000
S83.2 Tear of meniscus, current	0.012	0.988	0.000
S82.10 Fracture of upper end of tibia (closed)	0.011	0.989	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.991	0.009
H04.5 Stenosis and insufficiency of lachrymal passages	0.009	0.991	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.991	0.008
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.992	0.008
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.992	0.008
T40.2 Other opioids	0.000	0.992	0.008
T43.2 Other and unspecified antidepressants	0.000	0.992	0.008
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.992	0.008
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.992	0.008
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.992	0.008
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.992	0.007
T42.4 Benzodiazepines	0.000	0.993	0.007
T40.4 Other synthetic narcotics	0.000	0.993	0.007
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.993	0.007
T43.6 Psychostimulants with abuse potential	0.000	0.993	0.007
T40.1 Heroin	0.000	0.993	0.007
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.993	0.007
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.993	0.007
T40.6 Other and unspecified narcotics	0.000	0.993	0.007
T43.9 Psychotropic drug, unspecified	0.000	0.993	0.007
O94-O99 Other obstetric conditions, not elsewhere classified	0.007	0.993	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.007	0.993	0.000
T42.1 Iminostilbenes	0.000	0.994	0.006
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.994	0.006
T40.8 Lysergide [LSD]	0.000	0.994	0.006
T40.7 Cannabis (derivatives)	0.000	0.994	0.006
T40.5 Cocaine	0.000	0.994	0.006
T40.0 Opium	0.000	0.994	0.006
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.994	0.006
T40.3 Methadone	0.000	0.994	0.006
Z94.0 Kidney transplant status	0.006	0.994	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.994	0.006
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.994	0.006
T42.3 Barbiturates	0.000	0.994	0.006
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.994	0.006
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.994	0.006
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.994	0.006
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.994	0.006
T42.2 Succinimides and oxazolidinediones	0.000	0.994	0.006
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.994	0.006
T42.0 Hydantoin derivatives	0.000	0.994	0.006
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.994	0.006
T36 Poisoning by systemic antibiotics	0.000	0.994	0.006
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.994	0.006
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.994	0.006
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.994	0.005
H04.2 Epiphora	0.006	0.994	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.995	0.005
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.995	0.005
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.995	0.005
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.995	0.005
X62.9 Unspecified place	0.000	0.995	0.005
O97 Death from sequelae of direct obstetric causes	0.005	0.995	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.005	0.995	0.000
O95 Obstetric death of unspecified cause	0.005	0.995	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.000	0.995	0.005
O70.1 Second degree perineal laceration during delivery	0.005	0.995	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
H04 Disorders of lachrymal system	0.005	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.000	0.995	0.005
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.995	0.005
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.995	0.005
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.995	0.005
T44.0 Anticholinesterase agents	0.000	0.995	0.005
T47.2 Stimulant laxatives	0.000	0.995	0.005
T47.4 Other laxatives	0.000	0.995	0.005
T39.4 Antirheumatics, not elsewhere classified	0.000	0.995	0.005
T39.2 Pyrazolone derivatives	0.000	0.995	0.005
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.995	0.005
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.995	0.005
T47.7 Emetics	0.000	0.995	0.005
T47.5 Digestants	0.000	0.995	0.005
T47.3 Saline and osmotic laxatives	0.000	0.995	0.005
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
I08.1 Disorders of both mitral and tricuspid valves	0.005	0.995	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.995	0.005
T41.5 Therapeutic gases	0.000	0.995	0.004
T41.4 Anaesthetic, unspecified	0.000	0.995	0.004
T41.3 Local anaesthetics	0.000	0.995	0.004
T41.1 Intravenous anaesthetics	0.000	0.995	0.004
T41.0 Inhaled anaesthetics	0.000	0.995	0.004
T48.5 Anti-common-cold drugs	0.000	0.995	0.004
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.995	0.004
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.995	0.004
D12.6 Colon, unspecified	0.005	0.995	0.000
T39.0 Salicylates	0.000	0.995	0.005
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.995	0.004
T48.4 Expectorants	0.000	0.995	0.004
T48.3 Antitussives	0.000	0.995	0.004
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.995	0.004
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.995	0.004
T48.0 Oxytocic drugs	0.000	0.995	0.004
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.995	0.004
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.995	0.004
T47.6 Antidiarrhoeal drugs	0.000	0.996	0.004
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.004	0.996	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.996	0.004
T36.9 Systemic antibiotic, unspecified	0.000	0.996	0.004
T36.7 Antifungal antibiotics, systemically used	0.000	0.996	0.004
T36.6 Rifamycins	0.000	0.996	0.004
T36.5 Aminoglycosides	0.000	0.996	0.004
T36.2 Chloramphenicol group	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.996	0.004
T36.8 Other systemic antibiotics	0.000	0.996	0.004
T49.9 Topical agent, unspecified	0.000	0.996	0.004
T49.8 Other topical agents	0.000	0.996	0.004
T49.7 Dental drugs, topically applied	0.000	0.996	0.004
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.996	0.004
T49.5 Ophthalmological drugs and preparations	0.000	0.996	0.004
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.996	0.004
T49.3 Emollients, demulcents and protectants	0.000	0.996	0.004
T49.2 Local astringents and local detergents	0.000	0.996	0.004
T49.1 Antipruritics	0.000	0.996	0.004
T36.4 Tetracyclines	0.000	0.996	0.004
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.996	0.004
T36.3 Macrolides	0.000	0.996	0.004
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.996	0.004
T37.5 Antiviral drugs	0.000	0.996	0.004
T37.4 Anthelminthics	0.000	0.996	0.004
T37.3 Other antiprotozoal drugs	0.000	0.996	0.004
T37.1 Antimycobacterial drugs	0.000	0.996	0.004
T37.0 Sulphonamides	0.000	0.996	0.004
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.996	0.004
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.996	0.004
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.996	0.004
Z94 Transplanted organ and tissue status	0.004	0.996	0.000
T36.0 Penicillins	0.000	0.996	0.004
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.996	0.004
T38.9 Other and unspecified hormone antagonists	0.000	0.996	0.004
T38.7 Androgens and anabolic congeners	0.000	0.996	0.004
T38.4 Oral contraceptives	0.000	0.996	0.004
T38.2 Antithyroid drugs	0.000	0.996	0.004
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.996	0.004
Z94.8 Other transplanted organ and tissue status	0.004	0.996	0.000
T38.5 Other oestrogens and progestogens	0.000	0.996	0.004
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.996	0.004
T38.0 Glucocorticoids and synthetic analogues	0.000	0.996	0.004
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.996	0.004
T46.7 Peripheral vasodilators	0.000	0.996	0.004
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.996	0.004
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.996	0.004
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.996	0.004
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.004
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.996	0.004
H04.9 Disorder of lachrymal system, unspecified	0.004	0.996	0.000
O96.9 Death from unspecified obstetric cause	0.004	0.996	0.000
O96.1 Death from indirect obstetric cause	0.004	0.996	0.000
O96.0 Death from direct obstetric cause	0.004	0.996	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.004	0.996	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.004	0.996	0.000
O97.0 Death from sequelae of direct obstetric cause	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.996	0.004
T46.1 Calcium-channel blockers	0.000	0.996	0.004
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.996	0.003
H04.0 Dacryoadenitis	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.000	0.996	0.003
T50.5 Appetite depressants	0.000	0.996	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.996	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.996	0.003
T50.1 Loop [high-ceiling] diuretics	0.000	0.996	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.996	0.003
H04.6 Other changes in lachrymal passages	0.003	0.996	0.000
T39.1 4-Aminophenol derivatives	0.000	0.996	0.004
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.996	0.004
T50.8 Diagnostic agents	0.000	0.996	0.003
H04.8 Other disorders of lachrymal system	0.003	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.996	0.003
R47.8 Other and unspecified speech disturbances	0.004	0.996	0.000
Z94.2 Lung transplant status	0.003	0.996	0.000
Z94.4 Liver transplant status	0.003	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
M41.96 Scoliosis, unspecified (Lumbar region)	0.003	0.997	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.003	0.997	0.000
Z94.1 Heart transplant status	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.003
T45.4 Iron and its compounds	0.000	0.997	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.997	0.003
H04.4 Chronic inflammation of lachrymal passages	0.003	0.997	0.000
Z94.3 Heart and lungs transplant status	0.003	0.997	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.997	0.003
Z94.6 Bone transplant status	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
N31.8 Other neuromuscular dysfunction of bladder	0.003	0.997	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.003	0.997	0.000
Z94.5 Skin transplant status	0.003	0.997	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.997	0.003
T45.0 Antiallergic and antiemetic drugs	0.000	0.997	0.003
T45.5 Anticoagulants	0.000	0.997	0.003
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.997	0.003
Z94.7 Corneal transplant status	0.003	0.997	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.997	0.003
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.003	0.997	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.997	0.003
K02.9 Dental caries, unspecified	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.997	0.002
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.000	0.997	0.003
O70 Perineal laceration during delivery	0.003	0.997	0.000
Z49.1 Extracorporeal dialysis	0.003	0.997	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.997	0.003
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.003	0.997	0.000
H04.1 Other disorders of lachrymal gland	0.003	0.997	0.000
T83.2 Mechanical complication of graft of urinary organ	0.000	0.997	0.002
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.000	0.997	0.003
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.002	0.997	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.997	0.002
Z49.0 Preparatory care for dialysis	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
O70.2 Third degree perineal laceration during delivery	0.002	0.998	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
O70.3 Fourth degree perineal laceration during delivery	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
L53.9 Erythematous condition, unspecified	0.000	0.998	0.002
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.002	0.998	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.002	0.998	0.000
X62.0 Home	0.000	0.998	0.002
X62.7 Farm	0.000	0.998	0.002
X62.6 Industrial and construction area	0.000	0.998	0.002
X62.5 Trade and service area	0.000	0.998	0.002
X62.4 Street and highway	0.000	0.998	0.002
X62.3 Sports and athletics area	0.000	0.998	0.002
X62.2 School, other institution and public administrative area	0.000	0.998	0.002
X62.1 Residential institution	0.000	0.998	0.002
Z93.6 Other artificial openings of urinary tract status	0.000	0.998	0.002
C45.7 Mesothelioma of other sites	0.000	0.998	0.002
Z49 Care involving dialysis	0.002	0.998	0.000
Z93.0 Tracheostomy status	0.000	0.998	0.002
O70.9 Perineal laceration during delivery, unspecified	0.002	0.998	0.000
X62.8 Other specified place	0.000	0.998	0.002
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
C45 Mesothelioma	0.000	0.998	0.002
Z49.2 Other dialysis	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.998	0.002
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
K14.8 Other diseases of tongue	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
O66 Other obstructed labour	0.002	0.998	0.000
N60.8 Other benign mammary dysplasias	0.002	0.998	0.000
R47 Speech disturbances, not elsewhere classified	0.002	0.998	0.000
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.000	0.998	0.002
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
N21.0 Calculus in bladder	0.000	0.998	0.002
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
N60.3 Fibrosclerosis of breast	0.002	0.998	0.000
C45.2 Mesothelioma of pericardium	0.000	0.998	0.002
C45.1 Mesothelioma of peritoneum	0.000	0.998	0.002
O75.5 Delayed delivery after artificial rupture of membranes	0.002	0.998	0.000
N60 Benign mammary dysplasia	0.002	0.998	0.000
O75.9 Complication of labour and delivery, unspecified	0.002	0.998	0.000
N60.0 Solitary cyst of breast	0.002	0.998	0.000
O36.8 Maternal care for other specified foetal problems	0.002	0.998	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.002	0.998	0.000
G45.4 Transient global amnesia	0.000	0.998	0.002
O66.8 Other specified obstructed labour	0.002	0.998	0.000
O66.4 Failed trial of labour, unspecified	0.002	0.998	0.000
O75.3 Other infection during labour	0.002	0.998	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
C34.9 Bronchus or lung, unspecified	0.000	0.998	0.002
O66.2 Obstructed labour due to unusually large foetus	0.002	0.998	0.000
O75.4 Other complications of obstetric surgery and procedures	0.002	0.998	0.000
O75.1 Shock during or following labour and delivery	0.002	0.998	0.000
O66.9 Obstructed labour, unspecified	0.002	0.998	0.000
N60.9 Benign mammary dysplasia, unspecified	0.002	0.998	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.002	0.998	0.000
O66.1 Obstructed labour due to locked twins	0.002	0.998	0.000
O60-O75 Complications of labour and delivery	0.002	0.998	0.000
Z04.3 Examination and observation following other accident	0.000	0.998	0.002
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.002	0.998	0.000
S01.8 Open wound of other parts of head	0.002	0.998	0.000
Z93 Artificial opening status	0.000	0.998	0.002
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.001	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.001	0.998	0.000
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
L53.8 Other specified erythematous conditions	0.000	0.998	0.001
N21.1 Calculus in urethra	0.000	0.998	0.001
R76.8 Other specified abnormal immunological findings in serum	0.002	0.998	0.000
Z93.8 Other artificial opening status	0.000	0.998	0.001
D32.0 Cerebral meninges	0.000	0.998	0.002
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.998	0.001
O73 Retained placenta and membranes, without haemorrhage	0.001	0.998	0.000
G59.0 Diabetic mononeuropathy	0.001	0.998	0.000
N21.8 Other lower urinary tract calculus	0.000	0.998	0.001
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.001	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.001
I08 Multiple valve diseases	0.001	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.999	0.001
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.999	0.001
R23.3 Spontaneous ecchymoses	0.000	0.999	0.001
Z99.1 Dependence on respirator	0.001	0.999	0.000
O60 Preterm delivery	0.001	0.999	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.001	0.999	0.000
G45.3 Amaurosis fugax	0.000	0.999	0.001
G45.0 Vertebro-basilar artery syndrome	0.000	0.999	0.001
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.001	0.999	0.000
L03.0 Cellulitis of finger and toe	0.000	0.999	0.001
O70.0 First degree perineal laceration during delivery	0.001	0.999	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.001	0.999	0.000
R47.0 Dysphasia and aphasia	0.001	0.999	0.000
L53 Other erythematous conditions	0.000	0.999	0.001
N21 Calculus of lower urinary tract	0.000	0.999	0.001
O71 Other obstetric trauma	0.001	0.999	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.001	0.999	0.000
I84.9 Unspecified haemorrhoids without complication	0.001	0.999	0.000
O74 Complications of anaesthesia during labour and delivery	0.001	0.999	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
C67.0 Trigone of bladder	0.000	0.999	0.001
E13.9 Without complications	0.001	0.999	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.001	0.999	0.000
Z93.9 Artificial opening status, unspecified	0.000	0.999	0.001
O61 Failed induction of labour	0.001	0.999	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
N60.2 Fibroadenosis of breast	0.001	0.999	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.001	0.999	0.000
Z93.2 Ileostomy status	0.000	0.999	0.001
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
F05.9 Delirium, unspecified	0.001	0.999	0.000
N48.8 Other specified disorders of penis	0.001	0.999	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.001	0.999	0.000
X69.9 Unspecified place	0.000	0.999	0.001
C67.4 Posterior wall of bladder	0.000	0.999	0.001
E83.5 Disorders of calcium metabolism	0.001	0.999	0.000
O64.2 Obstructed labour due to face presentation	0.001	0.999	0.000
O71.7 Obstetric haematoma of pelvis	0.001	0.999	0.000
Z93.5 Cystostomy status	0.000	0.999	0.001
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.000	0.999	0.001
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.999	0.001
C67.8 Overlapping lesion of bladder	0.000	0.999	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.001	0.999	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.999	0.001
G62.9 Polyneuropathy, unspecified	0.000	0.999	0.001
O71.6 Obstetric damage to pelvic joints and ligaments	0.001	0.999	0.000
O73.0 Retained placenta, without haemorrhage	0.001	0.999	0.000
I49.8 Other specified cardiac arrhythmias	0.001	0.999	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.999	0.001
N64.1 Fat necrosis of breast	0.000	0.999	0.001
O67.8 Other intrapartum haemorrhage	0.001	0.999	0.000
O71.5 Other obstetric injury to pelvic organs	0.001	0.999	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.999	0.001
O60.3 Preterm delivery without spontaneous labour	0.001	0.999	0.000
O60.2 Preterm spontaneous labour with term delivery	0.001	0.999	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.001	0.999	0.000
O60.0 Preterm labour without delivery	0.001	0.999	0.000
O71.3 Obstetric laceration of cervix	0.001	0.999	0.000
X69.0 Home	0.000	0.999	0.001
O65 Obstructed labour due to maternal pelvic abnormality	0.001	0.999	0.000
I08.9 Multiple valve disease, unspecified	0.001	0.999	0.000
L53.3 Other chronic figurate erythema	0.000	0.999	0.001
L53.2 Erythema marginatum	0.000	0.999	0.001
L53.1 Erythema annulare centrifugum	0.000	0.999	0.001
O64.5 Obstructed labour due to compound presentation	0.001	0.999	0.000
O64.4 Obstructed labour due to shoulder presentation	0.001	0.999	0.000
O64.3 Obstructed labour due to brow presentation	0.001	0.999	0.000
O71.2 Postpartum inversion of uterus	0.001	0.999	0.000
O71.1 Rupture of uterus during labour	0.001	0.999	0.000
O71.0 Rupture of uterus before onset of labour	0.001	0.999	0.000
X61.4 Street and highway	0.000	0.999	0.001
O72 Postpartum haemorrhage	0.001	0.999	0.000
O61.8 Other failed induction of labour	0.001	0.999	0.000
O61.1 Failed instrumental induction of labour	0.001	0.999	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.001	0.999	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.001	0.999	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.001	0.999	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.001	0.999	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.001	0.999	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.001	0.999	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations