TreeWAS – Variant ID: rs10444533

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S52.50 Fracture of lower end of radius (closed)	0.000	0.978	0.022
R15 Faecal incontinence	0.000	0.983	0.017
S52.5 Fracture of lower end of radius	0.000	0.988	0.011
N70.1 Chronic salpingitis and oophoritis	0.011	0.989	0.000
H53.4 Visual field defects	0.000	0.989	0.011
S52.51 Fracture of lower end of radius (open)	0.000	0.990	0.009
K70 Alcoholic liver disease	0.009	0.991	0.000
K70.9 Alcoholic liver disease, unspecified	0.009	0.991	0.000
K72.0 Acute and subacute hepatic failure	0.009	0.991	0.000
K70.4 Alcoholic hepatic failure	0.009	0.991	0.000
J45.0 Predominantly allergic asthma	0.008	0.992	0.000
K72 Hepatic failure, not elsewhere classified	0.008	0.992	0.000
K70.1 Alcoholic hepatitis	0.007	0.993	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.993	0.007
K70.0 Alcoholic fatty liver	0.007	0.993	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.007	0.993	0.000
K63.1 Perforation of intestine (nontraumatic)	0.000	0.993	0.007
K72.1 Chronic hepatic failure	0.007	0.993	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.007	0.993	0.000
K70-K77 Diseases of liver	0.007	0.993	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.994	0.006
K70.3 Alcoholic cirrhosis of liver	0.006	0.994	0.000
K73 Chronic hepatitis, not elsewhere classified	0.006	0.994	0.000
K73.9 Chronic hepatitis, unspecified	0.006	0.994	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.005	0.995	0.000
K92.1 Melaena	0.000	0.995	0.005
K77 Liver disorders in diseases classified elsewhere	0.005	0.995	0.000
N70 Salpingitis and oophoritis	0.005	0.995	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.005	0.995	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.005	0.995	0.000
K71 Toxic liver disease	0.005	0.995	0.000
K72.9 Hepatic failure, unspecified	0.005	0.995	0.000
L71.1 Rhinophyma	0.000	0.995	0.005
D75.1 Secondary polycythaemia	0.004	0.996	0.000
D33.3 Cranial nerves	0.004	0.996	0.000
K76 Other diseases of liver	0.004	0.996	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.004	0.996	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.004	0.996	0.000
R03.1 Nonspecific low blood-pressure reading	0.004	0.996	0.000
Z48.0 Attention to surgical dressings and sutures	0.004	0.996	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.996	0.004
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.996	0.004
K77.8 Liver disorders in other diseases classified elsewhere	0.004	0.996	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
N70.0 Acute salpingitis and oophoritis	0.004	0.996	0.000
Z96.7 Presence of other bone and tendon implants	0.000	0.996	0.004
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.996	0.004
K76.6 Portal hypertension	0.004	0.996	0.000
K71.9 Toxic liver disease, unspecified	0.003	0.996	0.000
K71.8 Toxic liver disease with other disorders of liver	0.003	0.996	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.003	0.996	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.003	0.996	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.003	0.996	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.003	0.996	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.003	0.996	0.000
K71.2 Toxic liver disease with acute hepatitis	0.003	0.996	0.000
K71.0 Toxic liver disease with cholestasis	0.003	0.996	0.000
L71.9 Rosacea, unspecified	0.000	0.996	0.004
I61 Intracerebral haemorrhage	0.000	0.996	0.004
I67.1 Cerebral aneurysm, nonruptured	0.000	0.996	0.004
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.996	0.004
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.004	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
N70.9 Salpingitis and oophoritis, unspecified	0.004	0.996	0.000
K76.9 Liver disease, unspecified	0.004	0.996	0.000
I60 Subarachnoid haemorrhage	0.000	0.996	0.004
K71.1 Toxic liver disease with hepatic necrosis	0.003	0.996	0.000
K74 Fibrosis and cirrhosis of liver	0.004	0.996	0.000
R73.9 Hyperglycaemia, unspecified	0.004	0.996	0.000
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
N42.9 Disorder of prostate, unspecified	0.003	0.997	0.000
K76.5 Hepatic veno-occlusive disease	0.003	0.997	0.000
K76.4 Peliosis hepatis	0.003	0.997	0.000
K76.3 Infarction of liver	0.003	0.997	0.000
K76.2 Central haemorrhagic necrosis of liver	0.003	0.997	0.000
K76.1 Chronic passive congestion of liver	0.003	0.997	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.997	0.003
Z45.2 Adjustment and management of vascular access device	0.003	0.997	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.997	0.003
L71 Rosacea	0.000	0.997	0.003
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.997	0.003
K76.8 Other specified diseases of liver	0.003	0.997	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.003	0.997	0.000
K76.7 Hepatorenal syndrome	0.003	0.997	0.000
H53.2 Diplopia	0.000	0.997	0.003
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.997	0.003
I69 Sequelae of cerebrovascular disease	0.000	0.997	0.003
Z04.5 Examination and observation following other inflicted injury	0.000	0.997	0.003
N97.9 Female infertility, unspecified	0.000	0.997	0.003
I61.8 Other intracerebral haemorrhage	0.000	0.997	0.003
I60-I69 Cerebrovascular diseases	0.000	0.997	0.003
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.997	0.003
H53 Visual disturbances	0.000	0.997	0.003
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.997	0.003
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.997	0.003
I60.8 Other subarachnoid haemorrhage	0.000	0.997	0.003
I67.9 Cerebrovascular disease, unspecified	0.000	0.997	0.003
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.997	0.003
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.997	0.003
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.997	0.003
M16.0 Primary coxarthrosis, bilateral	0.003	0.997	0.000
K74.5 Biliary cirrhosis, unspecified	0.003	0.997	0.000
K74.4 Secondary biliary cirrhosis	0.003	0.997	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.003	0.997	0.000
K74.1 Hepatic sclerosis	0.003	0.997	0.000
I67 Other cerebrovascular diseases	0.000	0.997	0.003
Z04 Examination and observation for other reasons	0.000	0.997	0.003
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.997	0.003
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
K74.0 Hepatic fibrosis	0.003	0.997	0.000
D35.0 Adrenal gland	0.003	0.997	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.997	0.003
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.997	0.003
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.003	0.997	0.000
Y40.0 Penicillins	0.000	0.997	0.003
D75.8 Other specified diseases of blood and blood-forming organs	0.003	0.997	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.997	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.997	0.003
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.003	0.997	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.003	0.997	0.000
L71.0 Perioral dermatitis	0.000	0.997	0.002
Q63.2 Ectopic kidney	0.002	0.997	0.000
Q63.0 Accessory kidney	0.002	0.997	0.000
B37.9 Candidiasis, unspecified	0.002	0.997	0.000
H53.0 Amblyopia ex anopsia	0.000	0.997	0.002
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.997	0.002
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.998	0.002
H53.6 Night blindness	0.000	0.998	0.002
H53.5 Colour vision deficiencies	0.000	0.998	0.002
H53.3 Other disorders of binocular vision	0.000	0.998	0.002
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
Y83.3 Surgical operation with formation of external stoma	0.000	0.998	0.002
Z35.5 Supervision of elderly primigravida	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
K06 Other disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.998	0.002
I67.5 Moyamoya disease	0.000	0.998	0.002
I67.4 Hypertensive encephalopathy	0.000	0.998	0.002
I67.3 Progressive vascular leukoencephalopathy	0.000	0.998	0.002
Z04.6 General psychiatric examination, requested by authority	0.000	0.998	0.002
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.998	0.002
Z04.2 Examination and observation following work accident	0.000	0.998	0.002
Z04.0 Blood-alcohol and blood-drug test	0.000	0.998	0.002
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.002
L71.8 Other rosacea	0.000	0.998	0.002
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.998	0.002
B08.1 Molluscum contagiosum	0.000	0.998	0.002
K31.1 Adult hypertrophic pyloric stenosis	0.000	0.998	0.002
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.002	0.998	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
K75 Other inflammatory liver diseases	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
K06.0 Gingival recession	0.002	0.998	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.998	0.002
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.998	0.002
Z35 Supervision of high-risk pregnancy	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
Z04.3 Examination and observation following other accident	0.000	0.998	0.002
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.998	0.002
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.998	0.002
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.998	0.002
I62 Other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.998	0.002
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
S52.80 Fracture of other parts of forearm (closed)	0.002	0.998	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.002	0.998	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.998	0.002
R73 Elevated blood glucose level	0.002	0.998	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.998	0.002
D75.0 Familial erythrocytosis	0.002	0.998	0.000
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.998	0.002
Z12.0 Special screening examination for neoplasm of stomach	0.002	0.998	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.002	0.998	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.998	0.002
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
K06.1 Gingival enlargement	0.002	0.998	0.000
D33.4 Spinal cord	0.002	0.998	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.998	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.998	0.002
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.998	0.002
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.998	0.002
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.998	0.002
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.002	0.998	0.000
K75.1 Phlebitis of portal vein	0.002	0.998	0.000
R73.0 Abnormal glucose tolerance test	0.002	0.998	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.998	0.002
D17 Benign lipomatous neoplasm	0.002	0.998	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.998	0.002
Z35.6 Supervision of very young primigravida	0.000	0.998	0.002
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.998	0.002
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.998	0.002
K75.0 Abscess of liver	0.002	0.998	0.000
J38.4 Oedema of larynx	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
B91 Sequelae of poliomyelitis	0.002	0.998	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.002	0.998	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.998	0.002
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.002
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
S52.0 Fracture of upper end of ulna	0.001	0.998	0.000
I62.1 Nontraumatic extradural haemorrhage	0.000	0.998	0.002
I68.0 Cerebral amyloid angiopathy	0.000	0.998	0.001
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.998	0.001
S52.8 Fracture of other parts of forearm	0.001	0.998	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.998	0.001
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
D33.9 Central nervous system, unspecified	0.001	0.998	0.000
D33.7 Other specified parts of central nervous system	0.001	0.998	0.000
D33.1 Brain, infratentorial	0.001	0.998	0.000
H53.1 Subjective visual disturbances	0.000	0.998	0.002
J45 Asthma	0.002	0.998	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.998	0.001
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.002	0.998	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.998	0.002
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.001	0.998	0.000
K10.2 Inflammatory conditions of jaws	0.002	0.998	0.000
Y83.0 Surgical operation with transplant of whole organ	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.998	0.001
I65.1 Occlusion and stenosis of basilar artery	0.000	0.998	0.001
I63 Cerebral infarction	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.002
Z91.6 Personal history of other physical trauma	0.000	0.998	0.002
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.998	0.001
J45.1 Nonallergic asthma	0.001	0.998	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.001	0.998	0.000
D75.2 Essential thrombocytosis	0.001	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.001
S52 Fracture of forearm	0.001	0.998	0.001
D33.2 Brain, unspecified	0.001	0.999	0.000
D33.0 Brain, supratentorial	0.001	0.999	0.000
H53.9 Visual disturbance, unspecified	0.000	0.999	0.001
J98.0 Diseases of bronchus, not elsewhere classified	0.001	0.999	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.999	0.001
S52.81 Fracture of other parts of forearm (open)	0.001	0.999	0.000
J45.8 Mixed asthma	0.001	0.999	0.000
Z96.0 Presence of urogenital implants	0.000	0.999	0.001
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.001	0.999	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.001	0.999	0.000
D61.9 Aplastic anaemia, unspecified	0.001	0.999	0.000
G82.5 Tetraplegia, unspecified	0.000	0.999	0.001
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
G12.2 Motor neuron disease	0.001	0.999	0.000
H02.6 Xanthelasma of eyelid	0.000	0.999	0.001
Q53.1 Undescended testicle, unilateral	0.000	0.999	0.001
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
S52.10 Fracture of upper end of radius (closed)	0.001	0.999	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.999	0.001
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.999	0.001
S52.1 Fracture of upper end of radius	0.001	0.999	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.001	0.999	0.000
K75.9 Inflammatory liver disease, unspecified	0.001	0.999	0.000
Z04.1 Examination and observation following transport accident	0.000	0.999	0.001
C71.9 Brain, unspecified	0.000	0.999	0.001
G82.1 Spastic paraplegia	0.000	0.999	0.001
I22.1 Subsequent myocardial infarction of inferior wall	0.001	0.999	0.000
N90.6 Hypertrophy of vulva	0.001	0.999	0.000
N90.1 Moderate vulvar dysplasia	0.001	0.999	0.000
G82 Paraplegia and tetraplegia	0.000	0.999	0.001
M43.02 Spondylolysis (Cervical region)	0.001	0.999	0.000
I71.0 Dissection of aorta [any part]	0.000	0.999	0.001
M43.0 Spondylolysis	0.001	0.999	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
S52.9 Fracture of forearm, part unspecified	0.001	0.999	0.001
S52.4 Fracture of shafts of both ulna and radius	0.001	0.999	0.000
S52.3 Fracture of shaft of radius	0.001	0.999	0.000
C56 Malignant neoplasm of ovary	0.001	0.999	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.001	0.999	0.000
S52.7 Multiple fractures of forearm	0.001	0.999	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.999	0.001
D29.1 Prostate	0.000	0.999	0.001
S52.11 Fracture of upper end of radius (open)	0.001	0.999	0.000
M25.50 Pain in joint (Multiple sites)	0.001	0.999	0.000
S52.01 Fracture of upper end of ulna (open)	0.001	0.999	0.000
C24.0 Extrahepatic bile duct	0.000	0.999	0.001
D75.9 Disease of blood and blood-forming organs, unspecified	0.001	0.999	0.001
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.999	0.001
Y40.3 Macrolides	0.000	0.999	0.001
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.001	0.999	0.000
G82.4 Spastic tetraplegia	0.000	0.999	0.001
G82.3 Flaccid tetraplegia	0.000	0.999	0.001
G82.0 Flaccid paraplegia	0.000	0.999	0.001
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.999	0.001
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.001	0.999	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.001	0.999	0.000
M43.04 Spondylolysis (Thoracic region)	0.001	0.999	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.001	0.999	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.001	0.999	0.000
S52.31 Fracture of shaft of radius (open)	0.001	0.999	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.001	0.999	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.001	0.999	0.001
S52.90 Fracture of forearm, part unspecified (closed)	0.001	0.999	0.001
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
S52.2 Fracture of shaft of ulna	0.001	0.999	0.001
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.001	0.999	0.000
S52.71 Multiple fractures of forearm (open)	0.001	0.999	0.000
B94.8 Sequelae of other specified infectious and parasitic diseases	0.001	0.999	0.000
C71.4 Occipital lobe	0.000	0.999	0.001
S31.8 Open wound of other and unspecified parts of abdomen	0.001	0.999	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.001	0.999	0.000
S52.30 Fracture of shaft of radius (closed)	0.001	0.999	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.001	0.999	0.000
Q60-Q64 Congenital malformations of the urinary system	0.001	0.999	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.001	0.999	0.000
S52.70 Multiple fractures of forearm (closed)	0.001	0.999	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.999	0.001
X78.0 Home	0.001	0.999	0.000
Q64 Other congenital malformations of urinary system	0.001	0.999	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.001	0.999	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.999	0.001
E23.0 Hypopituitarism	0.000	0.999	0.001
K75.8 Other specified inflammatory liver diseases	0.001	0.999	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.999	0.000
S30.0 Contusion of lower back and pelvis	0.001	0.999	0.000
S36.1 Injury of liver or gallbladder	0.001	0.999	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.001	0.999	0.000
M43.09 Spondylolysis (Site unspecified)	0.001	0.999	0.000
C77.8 Lymph nodes of multiple regions	0.001	0.999	0.000
D48.1 Connective and other soft tissue	0.001	0.999	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.999	0.001
K76.0 Fatty (change of) liver, not elsewhere classified	0.001	0.999	0.000
N90.3 Dysplasia of vulva, unspecified	0.001	0.999	0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.001	0.999	0.000
N90.0 Mild vulvar dysplasia	0.001	0.999	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.999	0.001
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.999	0.001
K75.4 Autoimmune hepatitis	0.001	0.999	0.000
O04.4 Incomplete, without complication	0.001	0.999	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.001	0.999	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
Z02.8 Other examinations for administrative purposes	0.000	0.999	0.001
Z48.9 Surgical follow-up care, unspecified	0.001	0.999	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.001	0.999	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.001	0.999	0.000
S52.21 Fracture of shaft of ulna (open)	0.001	0.999	0.001
D23.5 Skin of trunk	0.001	0.999	0.000
J18.0 Bronchopneumonia, unspecified	0.000	0.999	0.001
N34.3 Urethral syndrome, unspecified	0.000	0.999	0.001
N90.4 Leukoplakia of vulva	0.001	0.999	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.001	0.999	0.000
Q64.8 Other specified congenital malformations of urinary system	0.001	0.999	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.999	0.000
Q64.6 Congenital diverticulum of bladder	0.001	0.999	0.000
Q64.5 Congenital absence of bladder and urethra	0.001	0.999	0.000
Q64.4 Malformation of urachus	0.001	0.999	0.000
Q64.2 Congenital posterior urethral valves	0.001	0.999	0.000
Q64.1 Exstrophy of urinary bladder	0.001	0.999	0.000
Q64.0 Epispadias	0.001	0.999	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.001	0.999	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.001	0.999	0.000
M10.00 Idiopathic gout (Multiple sites)	0.001	0.999	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.999	0.001
I63.8 Other cerebral infarction	0.001	0.999	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.001	0.999	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.001	0.999	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.999	0.001
Y40 Systemic antibiotics	0.000	0.999	0.001
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.001	0.999	0.000
Q62.8 Other congenital malformations of ureter	0.001	0.999	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.999	0.000
Q62.6 Malposition of ureter	0.001	0.999	0.000
Q62.5 Duplication of ureter	0.001	0.999	0.000
Q62.4 Agenesis of ureter	0.001	0.999	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.999	0.000
Q62.2 Congenital megaloureter	0.001	0.999	0.000
Q62.1 Atresia and stenosis of ureter	0.001	0.999	0.000
Q62.0 Congenital hydronephrosis	0.001	0.999	0.000
R68.8 Other specified general symptoms and signs	0.001	0.999	0.000
S00.3 Superficial injury of nose	0.000	0.999	0.001
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.001	0.999	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.999	0.001
I67.8 Other specified cerebrovascular diseases	0.000	0.999	0.001
M85.0 Fibrous dysplasia (monostotic)	0.000	0.999	0.001
O20.8 Other haemorrhage in early pregnancy	0.000	0.999	0.001
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.999	0.001
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
T14.1 Open wound of unspecified body region	0.001	0.999	0.000
W18.5 Trade and service area	0.000	0.999	0.001
Y40.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
Y40.6 Rifamycins	0.000	0.999	0.001
Y40.4 Tetracyclines	0.000	0.999	0.001
Y40.2 Chloramphenicol group	0.000	0.999	0.001
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.000	0.999	0.001
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
B94.9 Sequelae of unspecified infectious or parasitic disease	0.001	0.999	0.000
B94.2 Sequelae of viral hepatitis	0.001	0.999	0.000
B94.1 Sequelae of viral encephalitis	0.001	0.999	0.000
B94.0 Sequelae of trachoma	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
D68.2 Hereditary deficiency of other clotting factors	0.001	0.999	0.000
I67.2 Cerebral atherosclerosis	0.000	0.999	0.001
S27.3 Other injuries of lung	0.001	0.999	0.000
V49.6 Unspecified car occupant injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
O73 Retained placenta and membranes, without haemorrhage	0.001	0.999	0.000
Z48 Other surgical follow-up care	0.001	0.999	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.999	0.001
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.000	0.999	0.001
M85.08 Fibrous dysplasia (monostotic) (Other)	0.000	0.999	0.001
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.000	0.999	0.001
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.000	0.999	0.001
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.000	0.999	0.001
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.000	0.999	0.001
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.000	0.999	0.001
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.000	0.999	0.001
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.000	0.999	0.001
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.000	0.999	0.001
B08.5 Enteroviral vesicular pharyngitis	0.000	0.999	0.001
B08.4 Enteroviral vesicular stomatitis with exanthem	0.000	0.999	0.001
B08.3 Erythema infectiosum [fifth disease]	0.000	0.999	0.001
B08.2 Exanthema subitum [sixth disease]	0.000	0.999	0.001
B08.0 Other orthopoxvirus infections	0.000	0.999	0.001
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.999	0.001
R20.3 Hyperaesthesia	0.001	0.999	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.001	0.999	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.001	0.999	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.001	0.999	0.000
S52.20 Fracture of shaft of ulna (closed)	0.000	0.999	0.001
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
C43.5 Malignant melanoma of trunk	0.000	0.999	0.001
H57.1 Ocular pain	0.000	0.999	0.001
H60.1 Cellulitis of external ear	0.001	0.999	0.000
N90.5 Atrophy of vulva	0.001	0.999	0.000
S30.2 Contusion of external genital organs	0.001	0.999	0.000
Y40.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
Y40.5 Aminoglycosides	0.000	0.999	0.001
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
C71 Malignant neoplasm of brain	0.000	0.999	0.001
O28 Abnormal findings on antenatal screening of mother	0.001	0.999	0.000
M10.06 Idiopathic gout (Lower leg)	0.001	0.999	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
M60.08 Infective myositis (Other)	0.001	0.999	0.000
C71.7 Brain stem	0.000	0.999	0.001
C71.6 Cerebellum	0.000	0.999	0.001
C71.5 Cerebral ventricle	0.000	0.999	0.001
C71.2 Temporal lobe	0.000	0.999	0.001
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.999	0.001
O21.0 Mild hyperemesis gravidarum	0.001	0.999	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.001	0.999	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.001	0.999	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.001	0.999	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.001	0.999	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.001	0.999	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.001	0.999	0.000
S27.2 Traumatic heamopneumothorax	0.001	0.999	0.000
G80 Infantile cerebral palsy	0.000	0.999	0.001
R20 Disturbances of skin sensation	0.001	0.999	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.999	0.001
S02.10 Fracture of base of skull (closed)	0.000	0.999	0.001
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.999	0.001
C71.8 Overlapping lesion of brain	0.000	0.999	0.001
G80.8 Other infantile cerebral palsy	0.000	0.999	0.001
G80.4 Ataxic cerebral palsy	0.000	0.999	0.001
G80.3 Dyskinetic cerebral palsy	0.000	0.999	0.001
G80.0 Spastic cerebral palsy	0.000	0.999	0.001
I86.1 Scrotal varices	0.000	0.999	0.001
R20.0 Anaesthesia of skin	0.001	0.999	0.000
S52.6 Fracture of lower end of both ulna and radius	0.001	0.999	0.000
M43.12 Spondylolisthesis (Cervical region)	0.001	0.999	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.001	0.999	0.000
S22.30 Fracture of rib (closed)	0.001	0.999	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.001	0.999	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.001	0.999	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.999	0.001
G80.2 Infantile hemiplegia	0.000	0.999	0.001
G80.1 Spastic diplegia	0.000	0.999	0.001
J03.9 Acute tonsillitis, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations