TreeWAS – Variant ID: rs1045241

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D70-D77 Other diseases of blood and blood-forming organs	0.452	0.548	0.000
D70 Agranulocytosis	0.451	0.549	0.000
D75 Other diseases of blood and blood-forming organs	0.448	0.552	0.000
D73 Diseases of spleen	0.436	0.564	0.000
D75.2 Essential thrombocytosis	0.428	0.572	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.423	0.577	0.000
D73.0 Hyposplenism	0.405	0.595	0.000
D73.1 Hypersplenism	0.359	0.641	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.354	0.646	0.000
D75.1 Secondary polycythaemia	0.346	0.654	0.000
D73.9 Disease of spleen, unspecified	0.344	0.656	0.000
D73.4 Cyst of spleen	0.342	0.657	0.000
D75.0 Familial erythrocytosis	0.341	0.659	0.000
D73.5 Infarction of spleen	0.331	0.669	0.000
D73.3 Abscess of spleen	0.329	0.671	0.000
D74 Methaemoglobinaemia	0.324	0.676	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.324	0.676	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.324	0.676	0.000
D73.2 Chronic congestive splenomegaly	0.312	0.687	0.000
D76.3 Other histiocytosis syndromes	0.283	0.717	0.000
D72 Other disorders of white blood cells	0.257	0.743	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.254	0.746	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.254	0.746	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.254	0.746	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.251	0.749	0.000
D73.8 Other diseases of spleen	0.248	0.752	0.000
D74.9 Methaemoglobinaemia, unspecified	0.233	0.767	0.000
D74.8 Other methaemoglobinaemias	0.233	0.767	0.000
D74.0 Congenital methaemoglobinaemia	0.233	0.767	0.000
D72.9 Disorder of white blood cells, unspecified	0.184	0.816	0.000
D72.0 Genetic anomalies of leukocytes	0.184	0.816	0.000
D72.1 Eosinophilia	0.166	0.834	0.000
D72.8 Other specified disorders of white blood cells	0.145	0.855	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.136	0.864	0.000
D80-D89 Certain disorders involving the immune mechanism	0.132	0.868	0.000
D86 Sarcoidosis	0.131	0.869	0.000
D86.0 Sarcoidosis of lung	0.121	0.879	0.000
D55-D59 Haemolytic anaemias	0.111	0.889	0.000
D86.3 Sarcoidosis of skin	0.111	0.889	0.000
D82 Immunodeficiency associated with other major defects	0.108	0.892	0.000
D86.9 Sarcoidosis, unspecified	0.104	0.896	0.000
D83 Common variable immunodeficiency	0.102	0.898	0.000
D86.8 Sarcoidosis of other and combined sites	0.102	0.898	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.098	0.901	0.000
D86.1 Sarcoidosis of lymph nodes	0.098	0.902	0.000
D81 Combined immunodeficiencies	0.095	0.905	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.092	0.908	0.000
D58 Other hereditary haemolytic anaemias	0.092	0.908	0.000
D82.1 Di George's syndrome	0.091	0.909	0.000
D84 Other immunodeficiencies	0.089	0.911	0.000
D59 Acquired haemolytic anaemia	0.086	0.914	0.000
D57 Sickle-cell disorders	0.081	0.919	0.000
D83.9 Common variable immunodeficiency, unspecified	0.081	0.919	0.000
D55 Anaemia due to enzyme disorders	0.080	0.920	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.078	0.922	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.078	0.922	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.078	0.922	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.078	0.922	0.000
D82.2 Immunodeficiency with short-limbed stature	0.078	0.922	0.000
D82.0 Wiskott-Aldrich syndrome	0.078	0.922	0.000
D80 Immunodeficiency with predominantly antibody defects	0.078	0.922	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.077	0.923	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.074	0.926	0.000
D83.8 Other common variable immunodeficiencies	0.073	0.926	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.073	0.926	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.073	0.926	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.073	0.926	0.000
D56 Thalassaemia	0.073	0.927	0.000
D58.0 Hereditary spherocytosis	0.072	0.928	0.000
D81.9 Combined immunodeficiency, unspecified	0.068	0.932	0.000
D81.8 Other combined immunodeficiencies	0.068	0.932	0.000
D81.7 Major histocompatibility complex class II deficiency	0.068	0.932	0.000
D81.6 Major histocompatibility complex class I deficiency	0.068	0.932	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.068	0.932	0.000
D81.4 Nezelof's syndrome	0.068	0.932	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.068	0.932	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.068	0.932	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.068	0.932	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.068	0.932	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.067	0.932	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.067	0.933	0.000
D89.3 Immune reconstitution syndrome	0.066	0.934	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.066	0.934	0.000
D58.2 Other haemoglobinopathies	0.066	0.934	0.000
D58.1 Hereditary elliptocytosis	0.066	0.934	0.000
D84.9 Immunodeficiency, unspecified	0.066	0.934	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.064	0.936	0.000
D59.1 Other autoimmune haemolytic anaemias	0.064	0.936	0.000
D89.1 Cryoglobulinaemia	0.062	0.937	0.000
D59.8 Other acquired haemolytic anaemias	0.062	0.938	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.062	0.938	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.062	0.938	0.000
D59.3 Haemolytic-uraemic syndrome	0.062	0.938	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.062	0.938	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.062	0.938	0.000
D84.8 Other specified immunodeficiencies	0.061	0.938	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.061	0.939	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.060	0.939	0.000
D57.1 Sickle-cell anaemia without crisis	0.060	0.940	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.060	0.940	0.000
D57.8 Other sickle-cell disorders	0.058	0.941	0.000
D57.3 Sickle-cell trait	0.058	0.941	0.000
D57.2 Double heterozygous sickling disorders	0.058	0.941	0.000
D57.0 Sickle-cell anaemia with crisis	0.058	0.941	0.000
D84.1 Defects in the complement system	0.058	0.941	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.057	0.943	0.000
D55.8 Other anaemias due to enzyme disorders	0.057	0.943	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.057	0.943	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.057	0.943	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.057	0.943	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.057	0.943	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.057	0.943	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.057	0.943	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.056	0.943	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.056	0.944	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.056	0.944	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.056	0.944	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.056	0.944	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.056	0.944	0.000
D56.9 Thalassaemia, unspecified	0.052	0.947	0.000
D56.8 Other thalassaemias	0.052	0.947	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.052	0.947	0.000
D56.2 Delta-beta thalassaemia	0.052	0.947	0.000
D56.1 Beta thalassaemia	0.052	0.947	0.000
D56.0 Alpha thalassaemia	0.052	0.947	0.000
D56.3 Thalassaemia trait	0.046	0.954	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.045	0.955	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.955	0.045
D80.1 Nonfamilial hypogammaglobulinaemia	0.041	0.959	0.000
D60-D64 Aplastic and other anaemias	0.032	0.968	0.000
D50-D53 Nutritional anaemias	0.028	0.972	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.025	0.975	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.024	0.976	0.000
D53 Other nutritional anaemias	0.023	0.977	0.000
D61 Other aplastic anaemias	0.021	0.979	0.000
D53.9 Nutritional anaemia, unspecified	0.019	0.981	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.018	0.982	0.000
D67 Hereditary factor IX deficiency	0.018	0.982	0.000
D62 Acute posthaemorrhagic anaemia	0.018	0.982	0.000
D60.8 Other acquired pure red cell aplasias	0.017	0.982	0.000
D60.1 Transient acquired pure red cell aplasia	0.017	0.982	0.000
D60.0 Chronic acquired pure red cell aplasia	0.017	0.982	0.000
D61.0 Constitutional aplastic anaemia	0.017	0.983	0.000
Q65.8 Other congenital deformities of hip	0.017	0.983	0.000
Z22.3 Carrier of other specified bacterial diseases	0.017	0.983	0.000
D53.8 Other specified nutritional anaemias	0.016	0.983	0.000
D53.2 Scorbutic anaemia	0.016	0.983	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.016	0.983	0.000
D53.0 Protein deficiency anaemia	0.016	0.983	0.000
Q65 Congenital deformities of hip	0.016	0.984	0.000
F31 Bipolar affective disorder	0.000	0.984	0.016
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.016	0.984	0.000
D61.8 Other specified aplastic anaemias	0.015	0.984	0.000
D61.3 Idiopathic aplastic anaemia	0.015	0.984	0.000
D61.2 Aplastic anaemia due to other external agents	0.015	0.984	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.015	0.985	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.986	0.014
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.986	0.014
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.986	0.014
D52 Folate deficiency anaemia	0.013	0.986	0.001
D61.9 Aplastic anaemia, unspecified	0.014	0.986	0.000
Q68 Other congenital musculoskeletal deformities	0.013	0.986	0.000
Q74 Other congenital malformations of limb(s)	0.013	0.986	0.000
Z29.1 Prophylactic immunotherapy	0.013	0.987	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.013	0.987	0.000
D61.1 Drug-induced aplastic anaemia	0.013	0.987	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.987	0.013
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.013	0.987	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.987	0.013
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.987	0.013
F31.7 Bipolar affective disorder, currently in remission	0.000	0.987	0.013
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.987	0.013
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.987	0.013
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.987	0.013
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.988	0.012
D64 Other anaemias	0.012	0.988	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.012	0.988	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.012	0.988	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.012	0.988	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.988	0.012
Q24.8 Other specified congenital malformations of heart	0.012	0.988	0.000
F30-F39 Mood [affective] disorders	0.000	0.988	0.012
D66 Hereditary factor VIII deficiency	0.012	0.988	0.000
D68 Other coagulation defects	0.012	0.988	0.000
Q65.9 Congenital deformity of hip, unspecified	0.012	0.988	0.000
Q65.6 Unstable hip	0.012	0.988	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.012	0.988	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.012	0.988	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.012	0.988	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.012	0.988	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.012	0.988	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.012	0.988	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.011	0.988	0.000
Q75 Other congenital malformations of skull and face bones	0.011	0.988	0.000
Q73 Reduction defects of unspecified limb	0.011	0.988	0.000
Q72 Reduction defects of lower limb	0.011	0.988	0.000
Q71 Reduction defects of upper limb	0.011	0.988	0.000
Q70 Syndactyly	0.011	0.988	0.000
Q69 Polydactyly	0.011	0.988	0.000
Q24 Other congenital malformations of heart	0.011	0.989	0.000
Z22 Carrier of infectious disease	0.011	0.989	0.000
Q76 Congenital malformations of spine and bony thorax	0.011	0.989	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.011	0.989	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.011	0.989	0.000
Q67.6 Pectus excavatum	0.011	0.989	0.000
Q74.1 Congenital malformation of knee	0.011	0.989	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.989	0.011
Q79.8 Other congenital malformations of musculoskeletal system	0.011	0.989	0.000
D69 Purpura and other haemorrhagic conditions	0.011	0.989	0.000
F33 Recurrent depressive disorder	0.000	0.989	0.011
F31.8 Other bipolar affective disorders	0.000	0.989	0.011
Q38-Q45 Other congenital malformations of the digestive system	0.011	0.989	0.000
F39 Unspecified mood [affective] disorder	0.000	0.989	0.011
Q79.0 Congenital diaphragmatic hernia	0.011	0.989	0.000
D68.5 Primary Thrombophilia	0.011	0.989	0.000
Q00-Q07 Congenital malformations of the nervous system	0.011	0.989	0.000
F34 Persistent mood [affective] disorders	0.000	0.989	0.011
D52.8 Other folate deficiency anaemias	0.009	0.990	0.001
D52.1 Drug-induced folate deficiency anaemia	0.009	0.990	0.001
D52.0 Dietary folate deficiency anaemia	0.009	0.990	0.001
Q43 Other congenital malformations of intestine	0.010	0.990	0.000
Q78 Other osteochondrodysplasias	0.010	0.990	0.000
Q60-Q64 Congenital malformations of the urinary system	0.010	0.990	0.000
Q79.6 Ehlers-Danlos syndrome	0.010	0.990	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.990	0.010
Q67.5 Congenital deformity of spine	0.010	0.990	0.000
Q07 Other congenital malformations of nervous system	0.010	0.990	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.010	0.990	0.000
Q68.4 Congenital bowing of tibia and fibula	0.010	0.990	0.000
Q68.3 Congenital bowing of femur	0.010	0.990	0.000
Q68.2 Congenital deformity of knee	0.010	0.990	0.000
Q68.1 Congenital deformity of hand	0.010	0.990	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.010	0.990	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.990	0.010
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.990	0.010
Q74.9 Unspecified congenital malformation of limb(s)	0.010	0.990	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.010	0.990	0.000
Q74.3 Arthrogryposis multiplex congenita	0.010	0.990	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.010	0.990	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.010	0.990	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.010	0.990	0.000
Q79.5 Other congenital malformations of abdominal wall	0.010	0.990	0.000
Q79.4 Prune belly syndrome	0.010	0.990	0.000
Q79.3 Gastroschisis	0.010	0.990	0.000
Q79.2 Exomphalos	0.010	0.990	0.000
Q79.1 Other congenital malformations of diaphragm	0.010	0.990	0.000
F34.1 Dysthymia	0.000	0.990	0.010
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.990	0.010
Q67.8 Other congenital deformities of chest	0.010	0.990	0.000
Q67.7 Pectus carinatum	0.010	0.990	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.010	0.990	0.000
Q67.3 Plagiocephaly	0.010	0.990	0.000
Q67.2 Dolichocephaly	0.010	0.990	0.000
Q67.1 Compression facies	0.010	0.990	0.000
Q67.0 Facial asymmetry	0.010	0.990	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.010	0.990	0.000
Q66 Congenital deformities of feet	0.010	0.990	0.000
Q64 Other congenital malformations of urinary system	0.009	0.990	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.990	0.009
Q43.0 Meckel's diverticulum	0.009	0.991	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.009	0.991	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.009	0.991	0.000
D51 Vitamin B12 deficiency anaemia	0.009	0.991	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.009	0.991	0.000
D68.4 Acquired coagulation factor deficiency	0.009	0.991	0.000
Q76.1 Klippel-Feil syndrome	0.009	0.991	0.000
Q07.0 Arnold-Chiari syndrome	0.009	0.991	0.000
D64.4 Congenital dyserythropoietic anaemia	0.009	0.991	0.000
D64.3 Other sideroblastic anaemias	0.009	0.991	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.009	0.991	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.009	0.991	0.000
D64.0 Hereditary sideroblastic anaemia	0.009	0.991	0.000
Q35-Q37 Cleft lip and cleft palate	0.009	0.991	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.991	0.009
D63.1 Anaemia in other chronic diseases classified elsewhere	0.009	0.991	0.000
D68.0 Von Willebrand's disease	0.009	0.991	0.000
T83.2 Mechanical complication of graft of urinary organ	0.000	0.991	0.009
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.009	0.991	0.000
Q43.3 Congenital malformations of intestinal fixation	0.009	0.991	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.009	0.991	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.991	0.009
Z22.8 Carrier of other infectious diseases	0.009	0.991	0.000
F38 Other mood [affective] disorders	0.000	0.991	0.009
Q38 Other congenital malformations of tongue, mouth and pharynx	0.009	0.991	0.000
D69.1 Qualitative platelet defects	0.009	0.991	0.000
Q24.5 Malformation of coronary vessels	0.009	0.991	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.009	0.991	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.008	0.991	0.000
Q69.9 Polydactyly, unspecified	0.008	0.991	0.000
Q69.2 Accessory toe(s)	0.008	0.991	0.000
Q69.1 Accessory thumb(s)	0.008	0.991	0.000
Q69.0 Accessory finger(s)	0.008	0.991	0.000
Q70.9 Syndactyly, unspecified	0.008	0.991	0.000
Q70.4 Polysyndactyly	0.008	0.991	0.000
Q70.3 Webbed toes	0.008	0.991	0.000
Q70.2 Fused toes	0.008	0.991	0.000
Q70.1 Webbed fingers	0.008	0.991	0.000
Q70.0 Fused fingers	0.008	0.991	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.008	0.991	0.000
Q71.8 Other reduction defects of upper limb(s)	0.008	0.991	0.000
Q71.6 Lobster-claw hand	0.008	0.991	0.000
Q71.5 Longitudinal reduction defect of ulna	0.008	0.991	0.000
Q71.4 Longitudinal reduction defect of radius	0.008	0.991	0.000
Q71.3 Congenital absence of hand and finger(s)	0.008	0.991	0.000
Q71.2 Congenital absence of both forearm and hand	0.008	0.991	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.008	0.991	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.008	0.991	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.008	0.991	0.000
Q72.8 Other reduction defects of lower limb(s)	0.008	0.991	0.000
Q72.7 Split foot	0.008	0.991	0.000
Q72.6 Longitudinal reduction defect of fibula	0.008	0.991	0.000
Q72.5 Longitudinal reduction defect of tibia	0.008	0.991	0.000
Q72.4 Longitudinal reduction defect of femur	0.008	0.991	0.000
Q72.3 Congenital absence of foot and toe(s)	0.008	0.991	0.000
Q72.2 Congenital absence of both lower leg and foot	0.008	0.991	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.008	0.991	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.008	0.991	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.008	0.991	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.008	0.991	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.008	0.991	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.008	0.991	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.008	0.991	0.000
Q75.5 Oculomandibular dysostosis	0.008	0.991	0.000
Q75.4 Mandibulofacial dysostosis	0.008	0.991	0.000
Q75.3 Macrocephaly	0.008	0.991	0.000
Q75.2 Hypertelorism	0.008	0.991	0.000
Q75.1 Craniofacial dysostosis	0.008	0.991	0.000
Q75.0 Craniosynostosis	0.008	0.991	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.008	0.991	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.008	0.991	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.008	0.991	0.000
Q77.6 Chondroectodermal dysplasia	0.008	0.991	0.000
Q77.5 Diastrophic dysplasia	0.008	0.991	0.000
Q77.4 Achondroplasia	0.008	0.991	0.000
Q77.3 Chondrodysplasia punctata	0.008	0.991	0.000
Q77.2 Short rib syndrome	0.008	0.991	0.000
Q77.1 Thanatophoric short stature	0.008	0.991	0.000
Q77.0 Achondrogenesis	0.008	0.991	0.000
Q07.8 Other specified congenital malformations of nervous system	0.008	0.991	0.000
Q27 Other congenital malformations of peripheral vascular system	0.008	0.991	0.000
Q24.6 Congenital heart block	0.008	0.992	0.000
Q45 Other congenital malformations of digestive system	0.008	0.992	0.000
Z29 Need for other prophylactic measures	0.008	0.992	0.000
Q24.4 Congenital subaortic stenosis	0.008	0.992	0.000
Q24.3 Pulmonary infundibular stenosis	0.008	0.992	0.000
Q24.2 Cor triatriatum	0.008	0.992	0.000
Q24.1 Levocardia	0.008	0.992	0.000
Z22.9 Carrier of infectious disease, unspecified	0.008	0.992	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.008	0.992	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.008	0.992	0.000
Z22.2 Carrier of diphtheria	0.008	0.992	0.000
Z22.0 Carrier of typhoid	0.008	0.992	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.008	0.992	0.000
Q76.8 Other congenital malformations of bony thorax	0.008	0.992	0.000
Q76.7 Congenital malformation of sternum	0.008	0.992	0.000
Q76.6 Other congenital malformations of ribs	0.008	0.992	0.000
Q76.5 Cervical rib	0.008	0.992	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.008	0.992	0.000
Q76.2 Congenital spondylolisthesis	0.008	0.992	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.008	0.992	0.000
Q26 Congenital malformations of great veins	0.008	0.992	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.008	0.992	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.992	0.008
D64.8 Other specified anaemias	0.008	0.992	0.000
Q25 Congenital malformations of great arteries	0.008	0.992	0.000
F30 Manic episode	0.000	0.992	0.008
Q43.8 Other specified congenital malformations of intestine	0.008	0.992	0.000
D68.8 Other specified coagulation defects	0.008	0.992	0.000
Q63 Other congenital malformations of kidney	0.008	0.992	0.000
D69.8 Other specified haemorrhagic conditions	0.008	0.992	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.992	0.008
Q03 Congenital hydrocephalus	0.008	0.992	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.008	0.992	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.008	0.992	0.000
D68.1 Hereditary factor XI deficiency	0.008	0.992	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.992	0.008
F34.8 Other persistent mood [affective] disorders	0.000	0.992	0.008
F34.0 Cyclothymia	0.000	0.992	0.008
Q06 Other congenital malformations of spinal cord	0.008	0.992	0.000
Q01 Encephalocele	0.008	0.992	0.000
Q00 Anencephaly and similar malformations	0.008	0.992	0.000
Q02 Microcephaly	0.008	0.992	0.000
Q23 Congenital malformations of aortic and mitral valves	0.008	0.992	0.000
Q96 Turner's syndrome	0.008	0.992	0.000
Z24 Need for immunisation against certain single viral diseases	0.008	0.992	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.008	0.992	0.000
Z22.5 Carrier of viral hepatitis	0.008	0.992	0.000
Q40 Other congenital malformations of upper alimentary tract	0.008	0.992	0.000
Q24.0 Dextrocardia	0.008	0.992	0.000
Q04 Other congenital malformations of brain	0.008	0.992	0.000
D68.6 Other Thrombophilia	0.008	0.992	0.000
Q43.7 Persistent cloaca	0.008	0.992	0.000
Q43.6 Congenital fistula of rectum and anus	0.008	0.992	0.000
Q43.5 Ectopic anus	0.008	0.992	0.000
Q43.4 Duplication of intestine	0.008	0.992	0.000
Q43.2 Other congenital functional disorders of colon	0.008	0.992	0.000
Q43.1 Hirschsprung's disease	0.008	0.992	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.007	0.992	0.000
Q78.8 Other specified osteochondrodysplasias	0.007	0.992	0.000
Q78.6 Multiple congenital exostoses	0.007	0.992	0.000
Q78.5 Metaphyseal dysplasia	0.007	0.992	0.000
Q78.4 Enchondromatosis	0.007	0.992	0.000
Q78.3 Progressive diaphyseal dysplasia	0.007	0.992	0.000
Q78.2 Osteopetrosis	0.007	0.992	0.000
Q78.1 Polyostotic fibrous dysplasia	0.007	0.992	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.992	0.008
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.007	0.992	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.007	0.993	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.007	0.993	0.000
Q17 Other congenital malformations of ear	0.007	0.993	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.007	0.993	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.007	0.993	0.000
Q90 Down's syndrome	0.007	0.993	0.000
Q28 Other congenital malformations of circulatory system	0.007	0.993	0.000
Q66.7 Pes cavus	0.007	0.993	0.000
Q38.7 Pharyngeal pouch	0.007	0.993	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.007	0.993	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.007	0.993	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.007	0.993	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.007	0.993	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.007	0.993	0.000
Q66.6 Other congenital valgus deformities of feet	0.007	0.993	0.000
Q66.5 Congenital pes planus	0.007	0.993	0.000
Q66.4 Talipes calcaneovalgus	0.007	0.993	0.000
Q66.1 Talipes calcaneovarus	0.007	0.993	0.000
Q66.0 Talipes equinovarus	0.007	0.993	0.000
Q80-Q89 Other congenital malformations	0.007	0.993	0.000
Z24.5 Need for immunisation against rubella alone	0.007	0.993	0.000
D69.2 Other nonthrombocytopenic purpura	0.007	0.993	0.000
F30.9 Manic episode, unspecified	0.000	0.993	0.007
Q66.2 Metatarsus varus	0.007	0.993	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.007	0.993	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.007	0.993	0.000
Q64.8 Other specified congenital malformations of urinary system	0.007	0.993	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.007	0.993	0.000
Q64.6 Congenital diverticulum of bladder	0.007	0.993	0.000
Q64.5 Congenital absence of bladder and urethra	0.007	0.993	0.000
Q64.4 Malformation of urachus	0.007	0.993	0.000
Q64.2 Congenital posterior urethral valves	0.007	0.993	0.000
Q64.1 Exstrophy of urinary bladder	0.007	0.993	0.000
Q64.0 Epispadias	0.007	0.993	0.000
Q31 Congenital malformations of larynx	0.007	0.993	0.000
Q63.2 Ectopic kidney	0.007	0.993	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.007	0.993	0.000
Q66.9 Congenital deformity of feet, unspecified	0.007	0.993	0.000
Q66.3 Other congenital varus deformities of feet	0.007	0.993	0.000
Q05 Spina bifida	0.007	0.993	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.007	0.993	0.000
D69.0 Allergic purpura	0.007	0.993	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.007	0.993	0.000
D69.5 Secondary thrombocytopenia	0.007	0.993	0.000
F33.8 Other recurrent depressive disorders	0.000	0.993	0.007
Q16 Congenital malformations of ear causing impairment of hearing	0.007	0.993	0.000
Q13 Congenital malformations of anterior segment of eye	0.007	0.993	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.993	0.007
Q15 Other congenital malformations of eye	0.007	0.993	0.000
Q34 Other congenital malformations of respiratory system	0.007	0.993	0.000
Q33 Congenital malformations of lung	0.007	0.993	0.000
Q32 Congenital malformations of trachea and bronchus	0.007	0.993	0.000
Q30 Congenital malformations of nose	0.007	0.993	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.007	0.993	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.007	0.993	0.000
D51.2 Transcobalamin II deficiency	0.007	0.993	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.007	0.993	0.000
Q62.5 Duplication of ureter	0.007	0.993	0.000
Q45.8 Other specified congenital malformations of digestive system	0.007	0.993	0.000
Q10.0 Congenital ptosis	0.007	0.993	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.007	0.993	0.000
Q21 Congenital malformations of cardiac septa	0.007	0.993	0.000
Z20 Contact with and exposure to communicable diseases	0.007	0.993	0.000
Q38.6 Other congenital malformations of mouth	0.007	0.993	0.000
Q37 Cleft palate with cleft lip	0.007	0.993	0.000
Q36 Cleft lip	0.007	0.993	0.000
Q35 Cleft palate	0.007	0.993	0.000
Q22.1 Congenital pulmonary valve stenosis	0.007	0.993	0.000
Z28 Immunisation not carried out	0.007	0.993	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.007	0.993	0.000
Z26 Need for immunisation against other single infectious diseases	0.007	0.993	0.000
Z25 Need for immunisation against other single viral diseases	0.007	0.993	0.000
Z23 Need for immunisation against single bacterial diseases	0.007	0.993	0.000
Q23.0 Congenital stenosis of aortic valve	0.007	0.993	0.000
Q14 Congenital malformations of posterior segment of eye	0.006	0.993	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.993	0.007
Q22.5 Ebstein's anomaly	0.006	0.993	0.000
F38.8 Other specified mood [affective] disorders	0.000	0.993	0.006
F38.1 Other recurrent mood [affective] disorders	0.000	0.993	0.006
F38.0 Other single mood [affective] disorders	0.000	0.993	0.006
Q38.8 Other congenital malformations of pharynx	0.006	0.993	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.006	0.993	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.006	0.993	0.000
Q38.3 Other congenital malformations of tongue	0.006	0.993	0.000
Q38.2 Macroglossia	0.006	0.993	0.000
Q38.1 Ankyloglossia	0.006	0.993	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.006	0.993	0.000
Q96.9 Turner's syndrome, unspecified	0.006	0.993	0.000
Q61 Cystic kidney disease	0.007	0.993	0.000
D63.0 Anaemia in neoplastic disease	0.007	0.993	0.000
D69.9 Haemorrhagic condition, unspecified	0.006	0.993	0.000
Q27.3 Peripheral arteriovenous malformation	0.006	0.993	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations