TreeWAS – Variant ID: rs10457678

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.589	0.411	0.000
J44 Other chronic obstructive pulmonary disease	0.571	0.429	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.568	0.432	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.459	0.541	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.395	0.605	0.000
J40-J47 Chronic lower respiratory diseases	0.029	0.971	0.000
J46 Status asthmaticus	0.023	0.977	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.979	0.021
J41 Simple and mucopurulent chronic bronchitis	0.021	0.979	0.000
J09-J18 Influenza and pneumonia	0.017	0.983	0.000
J18.0 Bronchopneumonia, unspecified	0.017	0.983	0.000
Chapter X Diseases of the respiratory system	0.017	0.983	0.000
J10 Influenza due to identified influenza virus	0.016	0.984	0.000
J18 Pneumonia, organism unspecified	0.016	0.984	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.015	0.984	0.000
J41.1 Mucopurulent chronic bronchitis	0.015	0.984	0.000
J41.0 Simple chronic bronchitis	0.015	0.984	0.000
J00-J06 Acute upper respiratory infections	0.015	0.985	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.015	0.985	0.000
J42 Unspecified chronic bronchitis	0.015	0.985	0.000
J11 Influenza, virus not identified	0.014	0.986	0.000
J60-J70 Lung diseases due to external agents	0.014	0.986	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.014	0.986	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.014	0.986	0.000
J90-J94 Other diseases of pleura	0.014	0.986	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.014	0.986	0.000
J01 Acute sinusitis	0.014	0.986	0.000
J18.8 Other pneumonia, organism unspecified	0.013	0.987	0.000
J94 Other pleural conditions	0.013	0.987	0.000
J45 Asthma	0.013	0.987	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.013	0.987	0.000
J14 Pneumonia due to Haemophilus influenzae	0.013	0.987	0.000
J01.9 Acute sinusitis, unspecified	0.013	0.987	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.013	0.987	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.013	0.987	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.012	0.987	0.000
J09 Influenza due to certain identified influenza virus	0.012	0.987	0.000
J04 Acute laryngitis and tracheitis	0.013	0.987	0.000
J94.8 Other specified pleural conditions	0.012	0.988	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.012	0.988	0.000
J67.2 Bird fancier's lung	0.012	0.988	0.000
J12 Viral pneumonia, not elsewhere classified	0.012	0.988	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.012	0.988	0.000
J18.2 Hypostatic pneumonia, unspecified	0.012	0.988	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.012	0.988	0.000
J47 Bronchiectasis	0.012	0.988	0.000
N85.4 Malposition of uterus	0.000	0.989	0.011
J20-J22 Other acute lower respiratory infections	0.011	0.989	0.000
J00 Acute nasopharyngitis [common cold]	0.011	0.989	0.000
J17 Pneumonia in diseases classified elsewhere	0.011	0.989	0.000
J04.1 Acute tracheitis	0.011	0.989	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.011	0.989	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.011	0.989	0.000
J05.1 Acute epiglottitis	0.011	0.989	0.000
J94.1 Fibrothorax	0.011	0.989	0.000
J70 Respiratory conditions due to other external agents	0.011	0.989	0.000
J43 Emphysema	0.011	0.989	0.000
J01.4 Acute pansinusitis	0.011	0.989	0.000
J11.8 Influenza with other manifestations, virus not identified	0.010	0.989	0.000
J91 Pleural effusion in conditions classified elsewhere	0.011	0.989	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.010	0.989	0.000
J66 Airway disease due to specific organic dust	0.010	0.989	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.010	0.989	0.000
J62 Pneumoconiosis due to dust containing silica	0.010	0.989	0.000
J65 Pneumoconiosis associated with tuberculosis	0.010	0.989	0.000
J06.9 Acute upper respiratory infection, unspecified	0.010	0.990	0.000
J93 Pneumothorax	0.010	0.990	0.000
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.010	0.990	0.000
J67.7 Air-conditioner and humidifier lung	0.010	0.990	0.000
J67.6 Maple-bark-stripper's lung	0.010	0.990	0.000
J67.5 Mushroom-worker's lung	0.010	0.990	0.000
J67.4 Maltworker's lung	0.010	0.990	0.000
J67.3 Suberosis	0.010	0.990	0.000
J67.1 Bagassosis	0.010	0.990	0.000
J67.0 Farmer's lung	0.010	0.990	0.000
J40 Bronchitis, not specified as acute or chronic	0.010	0.990	0.000
J01.8 Other acute sinusitis	0.010	0.990	0.000
J01.3 Acute sphenoidal sinusitis	0.010	0.990	0.000
J01.2 Acute ethmoidal sinusitis	0.010	0.990	0.000
J01.1 Acute frontal sinusitis	0.010	0.990	0.000
J45.8 Mixed asthma	0.010	0.990	0.000
J11.0 Influenza with pneumonia, virus not identified	0.010	0.990	0.000
J92 Pleural plaque	0.010	0.990	0.000
J64 Unspecified pneumoconiosis	0.010	0.990	0.000
J94.9 Pleural condition, unspecified	0.010	0.990	0.000
J94.0 Chylous effusion	0.010	0.990	0.000
J45.1 Nonallergic asthma	0.010	0.990	0.000
J45.0 Predominantly allergic asthma	0.010	0.990	0.000
J94.2 Haemothorax	0.010	0.990	0.000
J86 Pyothorax	0.009	0.990	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.009	0.991	0.000
I20.0 Unstable angina	0.009	0.991	0.000
J05.0 Acute obstructive laryngitis [croup]	0.009	0.991	0.000
J16.8 Pneumonia due to other specified infectious organisms	0.009	0.991	0.000
J16.0 Chlamydial pneumonia	0.009	0.991	0.000
J04.2 Acute laryngotracheitis	0.009	0.991	0.000
J60 Coalworker's pneumoconiosis	0.009	0.991	0.000
J12.2 Parainfluenza virus pneumonia	0.009	0.991	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.009	0.991	0.000
J06.0 Acute laryngopharyngitis	0.009	0.991	0.000
J01.0 Acute maxillary sinusitis	0.009	0.991	0.000
J12.8 Other viral pneumonia	0.009	0.991	0.000
J12.3 Human metapneumovirus pneumonia	0.009	0.991	0.000
J12.1 Respiratory syncytial virus pneumonia	0.009	0.991	0.000
J12.0 Adenoviral pneumonia	0.009	0.991	0.000
J93.9 Pneumothorax, unspecified	0.009	0.991	0.000
J70.1 Chronic and other pulmonary manifestations due to radiation	0.008	0.991	0.000
J04.0 Acute laryngitis	0.008	0.992	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.008	0.992	0.000
J17.3 Pneumonia in parasitic diseases	0.008	0.992	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.008	0.992	0.000
J69 Pneumonitis due to solids and liquids	0.008	0.992	0.000
J12.9 Viral pneumonia, unspecified	0.008	0.992	0.000
J93.1 Other spontaneous pneumothorax	0.008	0.992	0.000
J92.9 Pleural plaque without asbestos	0.008	0.992	0.000
J20 Acute bronchitis	0.008	0.992	0.000
J70.9 Respiratory conditions due to unspecified external agent	0.008	0.992	0.000
J70.8 Respiratory conditions due to other specified external agents	0.008	0.992	0.000
J70.4 Drug-induced interstitial lung disorder, unspecified	0.008	0.992	0.000
J70.3 Chronic drug-induced interstitial lung disorders	0.008	0.992	0.000
J70.2 Acute drug-induced interstitial lung disorders	0.008	0.992	0.000
J70.0 Acute pulmonary manifestations due to radiation	0.008	0.992	0.000
J21 Acute bronchiolitis	0.008	0.992	0.000
J22 Unspecified acute lower respiratory infection	0.008	0.992	0.000
J43.1 Panlobular emphysema	0.008	0.992	0.000
J43.0 MacLeod's syndrome	0.008	0.992	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.008	0.992	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.008	0.992	0.000
J03 Acute tonsillitis	0.008	0.992	0.000
J62.8 Pneumoconiosis due to other dust containing silica	0.008	0.992	0.000
J62.0 Pneumoconiosis due to talc dust	0.008	0.992	0.000
J63.8 Pneumoconiosis due to other specified inorganic dusts	0.008	0.992	0.000
J63.5 Stannosis	0.008	0.992	0.000
J63.4 Siderosis	0.008	0.992	0.000
J63.3 Graphite fibrosis (of lung)	0.008	0.992	0.000
J63.2 Berylliosis	0.008	0.992	0.000
J63.1 Bauxite fibrosis (of lung)	0.008	0.992	0.000
J63.0 Aluminosis (of lung)	0.008	0.992	0.000
J66.8 Airway disease due to other specific organic dusts	0.008	0.992	0.000
J66.2 Cannabinosis	0.008	0.992	0.000
J66.1 Flax-dresser's disease	0.008	0.992	0.000
J66.0 Byssinosis	0.008	0.992	0.000
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours	0.008	0.992	0.000
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours	0.008	0.992	0.000
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours	0.008	0.992	0.000
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours	0.008	0.992	0.000
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified	0.008	0.992	0.000
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours	0.008	0.992	0.000
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours	0.008	0.992	0.000
J43.8 Other emphysema	0.008	0.992	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.008	0.992	0.000
J86.9 Pyothorax without fistula	0.008	0.992	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.008	0.992	0.000
J18.9 Pneumonia, unspecified	0.008	0.992	0.000
J02 Acute pharyngitis	0.008	0.992	0.000
J17.2 Pneumonia in mycoses	0.007	0.992	0.000
J93.8 Other pneumothorax	0.007	0.992	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.007	0.993	0.000
J86.0 Pyothorax with fistula	0.007	0.993	0.000
J69.8 Pneumonitis due to other solids and liquids	0.007	0.993	0.000
J15.9 Bacterial pneumonia, unspecified	0.007	0.993	0.000
J15.3 Pneumonia due to streptococcus, group B	0.007	0.993	0.000
J15.8 Other bacterial pneumonia	0.007	0.993	0.000
J15.2 Pneumonia due to staphylococcus	0.007	0.993	0.000
J85 Abscess of lung and mediastinum	0.007	0.993	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.006	0.993	0.000
J43.2 Centrilobular emphysema	0.006	0.994	0.000
J15.5 Pneumonia due to Escherichia coli	0.006	0.994	0.000
R52.1 Chronic intractable pain	0.000	0.994	0.006
R52.9 Pain, unspecified	0.000	0.994	0.006
J69.1 Pneumonitis due to oils and essences	0.006	0.994	0.000
J20.7 Acute bronchitis due to echovirus	0.006	0.994	0.000
J20.6 Acute bronchitis due to rhinovirus	0.006	0.994	0.000
J20.5 Acute bronchitis due to respiratory syncytial virus	0.006	0.994	0.000
J20.4 Acute bronchitis due to parainfluenza virus	0.006	0.994	0.000
J20.3 Acute bronchitis due to coxsackie virus	0.006	0.994	0.000
J20.2 Acute bronchitis due to streptococcus	0.006	0.994	0.000
J20.1 Acute bronchitis due to Haemophilus influenzae	0.006	0.994	0.000
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.006	0.994	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.006	0.994	0.000
J20.8 Acute bronchitis due to other specified organisms	0.006	0.994	0.000
J21.8 Acute bronchiolitis due to other specified organisms	0.006	0.994	0.000
J21.1 Acute bronchiolitis due to human metapneumovirus	0.006	0.994	0.000
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.006	0.994	0.000
I51.9 Heart disease, unspecified	0.006	0.994	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.006	0.994	0.000
J03.0 Streptococcal tonsillitis	0.006	0.994	0.000
J18.1 Lobar pneumonia, unspecified	0.006	0.994	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.006	0.994	0.000
J15.1 Pneumonia due to Pseudomonas	0.006	0.994	0.000
J20.9 Acute bronchitis, unspecified	0.006	0.994	0.000
J90 Pleural effusion, not elsewhere classified	0.006	0.994	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.006	0.994	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.006	0.994	0.000
J21.9 Acute bronchiolitis, unspecified	0.006	0.994	0.000
T90.9 Sequelae of unspecified injury of head	0.006	0.994	0.000
T90 Sequelae of injuries of head	0.006	0.994	0.000
J93.0 Spontaneous tension pneumothorax	0.005	0.994	0.000
J92.0 Pleural plaque with presence of asbestos	0.005	0.994	0.000
S90-S99 Injuries to the ankle and foot	0.006	0.994	0.000
S92.41 Fracture of great toe (open)	0.005	0.995	0.000
J15.4 Pneumonia due to other streptococci	0.005	0.995	0.000
S92.4 Fracture of great toe	0.005	0.995	0.000
S90 Superficial injury of ankle and foot	0.005	0.995	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.005	0.995	0.000
Z57 Occupational exposure to risk-factors	0.005	0.995	0.000
R52 Pain, not elsewhere classified	0.000	0.995	0.005
S91 Open wound of ankle and foot	0.005	0.995	0.000
S93.0 Dislocation of ankle joint	0.005	0.995	0.000
S92 Fracture of foot, except ankle	0.005	0.995	0.000
I20.8 Other forms of angina pectoris	0.005	0.995	0.000
J85.3 Abscess of mediastinum	0.005	0.995	0.000
J85.0 Gangrene and necrosis of lung	0.005	0.995	0.000
S93.1 Dislocation of toe(s)	0.005	0.995	0.000
J02.0 Streptococcal pharyngitis	0.005	0.995	0.000
Z57.3 Occupational exposure to other air contaminants	0.005	0.995	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.005	0.995	0.000
S92.1 Fracture of talus	0.005	0.995	0.000
S91.0 Open wound of ankle	0.005	0.995	0.000
I20 Angina pectoris	0.005	0.995	0.000
S92.10 Fracture of talus (closed)	0.005	0.995	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
J85.1 Abscess of lung with pneumonia	0.004	0.995	0.000
S92.40 Fracture of great toe (closed)	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
J80 Adult respiratory distress syndrome	0.005	0.995	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.004	0.995	0.000
T90.1 Sequelae of open wound of head	0.005	0.995	0.000
S90.8 Other superficial injuries of ankle and foot	0.004	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
S91.3 Open wound of other parts of foot	0.004	0.996	0.000
S93.4 Sprain and strain of ankle	0.004	0.996	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.004	0.996	0.000
S93.5 Sprain and strain of toe(s)	0.004	0.996	0.000
T90.3 Sequelae of injury of cranial nerves	0.004	0.996	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.004	0.996	0.000
S90.1 Contusion of toe(s) without damage to nail	0.004	0.996	0.000
J84 Other interstitial pulmonary diseases	0.004	0.996	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.004	0.996	0.000
R52.0 Acute pain	0.000	0.996	0.004
Z57.2 Occupational exposure to dust	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.004	0.996	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
S98 Traumatic amputation of ankle and foot	0.004	0.996	0.000
S97 Crushing injury of ankle and foot	0.004	0.996	0.000
S95 Injury of blood vessels at ankle and foot level	0.004	0.996	0.000
S94 Injury of nerves at ankle and foot level	0.004	0.996	0.000
T90.5 Sequelae of intracranial injury	0.004	0.996	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.004	0.996	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.004	0.996	0.000
S90.2 Contusion of toe(s) with damage to nail	0.004	0.996	0.000
S90.0 Contusion of ankle	0.004	0.996	0.000
Z57.8 Occupational exposure to other risk-factors	0.004	0.996	0.000
T90.0 Sequelae of superficial injury of head	0.004	0.996	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.004	0.996	0.000
Z57.7 Occupational exposure to vibration	0.004	0.996	0.000
Z57.6 Occupational exposure to extreme temperature	0.004	0.996	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.004	0.996	0.000
Z57.1 Occupational exposure to radiation	0.004	0.996	0.000
Z57.0 Occupational exposure to noise	0.004	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.004	0.996	0.000
T47.4 Other laxatives	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
T42.4 Benzodiazepines	0.004	0.996	0.000
S91.7 Multiple open wounds of ankle and foot	0.004	0.996	0.000
S91.2 Open wound of toe(s) with damage to nail	0.004	0.996	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
J85.2 Abscess of lung without pneumonia	0.003	0.996	0.001
S92.9 Fracture of foot, unspecified	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
T90.4 Sequelae of injury of eye and orbit	0.004	0.996	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
S92.11 Fracture of talus (open)	0.004	0.996	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
I20.1 Angina pectoris with documented spasm	0.004	0.996	0.000
S91.1 Open wound of toe(s) without damage to nail	0.004	0.996	0.000
O04.9 Complete or unspecified, without complication	0.000	0.996	0.004
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
S90.3 Contusion of other and unspecified parts of foot	0.004	0.996	0.000
J33.0 Polyp of nasal cavity	0.000	0.996	0.004
K63.9 Disease of intestine, unspecified	0.000	0.996	0.004
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
J84.8 Other specified interstitial pulmonary diseases	0.004	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.004	0.996	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.004	0.996	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.004	0.996	0.000
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
O04.4 Incomplete, without complication	0.000	0.996	0.004
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
G54.6 Phantom limb syndrome with pain	0.004	0.996	0.000
M81.9 Osteoporosis, unspecified	0.000	0.996	0.004
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.996	0.000
G54 Nerve root and plexus disorders	0.004	0.996	0.000
S92.0 Fracture of calcaneus	0.003	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.996	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
O04 Medical abortion	0.000	0.997	0.003
S93.40 Sprain of unspecified ligament of ankle	0.003	0.997	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
J84.0 Alveolar and parietoalveolar conditions	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
R52.2 Other chronic pain	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.997	0.000
T39.2 Pyrazolone derivatives	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.003	0.997	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.003	0.997	0.000
G58.8 Other specified mononeuropathies	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
S62.60 Fracture of other finger (closed)	0.003	0.997	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.003	0.997	0.000
S94.8 Injury of other nerves at ankle and foot level	0.003	0.997	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.003	0.997	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.003	0.997	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.003	0.997	0.000
S94.1 Injury of medial plantar nerve	0.003	0.997	0.000
S94.0 Injury of lateral plantar nerve	0.003	0.997	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.003	0.997	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.003	0.997	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.003	0.997	0.000
S95.2 Injury of dorsal vein of foot	0.003	0.997	0.000
S95.1 Injury of plantar artery of foot	0.003	0.997	0.000
S95.0 Injury of dorsal artery of foot	0.003	0.997	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.997	0.000
S97.1 Crushing injury of toe(s)	0.003	0.997	0.000
S97.0 Crushing injury of ankle	0.003	0.997	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.003	0.997	0.000
S98.3 Traumatic amputation of other parts of foot	0.003	0.997	0.000
S98.2 Traumatic amputation of two or more toes	0.003	0.997	0.000
S98.1 Traumatic amputation of one toe	0.003	0.997	0.000
S98.0 Traumatic amputation of foot at ankle level	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
J95-J99 Other diseases of the respiratory system	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
S92.31 Fracture of metatarsal bone (open)	0.003	0.997	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.997	0.003
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.997	0.003
S92.91 Fracture of foot, unspecified (open)	0.003	0.997	0.000
S92.90 Fracture of foot, unspecified (closed)	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.997	0.003
S72.40 Fracture of lower end of femur (closed)	0.000	0.997	0.003
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.003	0.997	0.000
T36.0 Penicillins	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
I50.9 Heart failure, unspecified	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
T90.8 Sequelae of other specified injuries of head	0.003	0.997	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.997	0.003
H44.2 Degenerative myopia	0.000	0.997	0.003
S92.71 Multiple fractures of foot (open)	0.003	0.997	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.997	0.003
S51.9 Open wound of forearm, part unspecified	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
G54.5 Neuralgic amyotrophy	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
G54.0 Brachial plexus disorders	0.003	0.997	0.000
M25.53 Pain in joint (Forearm)	0.000	0.997	0.003
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.997	0.003
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.997	0.003
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.997	0.003
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
G54.7 Phantom limb syndrome without pain	0.003	0.997	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.003	0.997	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.003	0.997	0.000
G54.1 Lumbosacral plexus disorders	0.003	0.997	0.000
S92.01 Fracture of calcaneus (open)	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.000	0.997	0.003
O04.7 Complete or unspecified, complicated by embolism	0.000	0.997	0.003
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.997	0.003
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.997	0.003
O04.3 Incomplete, with other and unspecified complications	0.000	0.997	0.003
O04.2 Incomplete, complicated by embolism	0.000	0.997	0.003
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
J03.9 Acute tonsillitis, unspecified	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
J43.9 Emphysema, unspecified	0.003	0.997	0.000
L50.9 Urticaria, unspecified	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.003	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.997	0.000
X63.0 Home	0.003	0.997	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
J81 Pulmonary oedema	0.003	0.997	0.000
J96 Respiratory failure, not elsewhere classified	0.002	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.997	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.997	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.003	0.997	0.000
K74.3 Primary biliary cirrhosis	0.003	0.997	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.997	0.003
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.997	0.000
G54.8 Other nerve root and plexus disorders	0.002	0.997	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.998	0.002
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations