TreeWAS – Variant ID: rs10458561

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R03.1 Nonspecific low blood-pressure reading	0.000	0.951	0.049
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.964	0.036
F33.9 Recurrent depressive disorder, unspecified	0.000	0.982	0.018
D32.0 Cerebral meninges	0.000	0.984	0.016
M22.8 Other disorders of patella	0.015	0.985	0.000
M22.2 Patellofemoral disorders	0.015	0.985	0.000
Z97 Presence of other devices	0.000	0.986	0.014
M22 Disorders of patella	0.014	0.986	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.013	0.987	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.988	0.012
Z97.0 Presence of artificial eye	0.000	0.988	0.012
M34.9 Systemic sclerosis, unspecified	0.012	0.988	0.000
K66.0 Peritoneal adhesions	0.012	0.988	0.000
F33 Recurrent depressive disorder	0.000	0.988	0.012
M22.3 Other derangements of patella	0.012	0.988	0.000
D32 Benign neoplasm of meninges	0.000	0.988	0.012
D32.9 Meninges, unspecified	0.000	0.989	0.011
F31 Bipolar affective disorder	0.000	0.989	0.011
M22.9 Disorder of patella, unspecified	0.010	0.990	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.990	0.010
Z97.3 Presence of spectacles and contact lenses	0.000	0.990	0.010
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.990	0.010
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.990	0.010
M22.1 Recurrent subluxation of patella	0.010	0.990	0.000
H81.1 Benign paroxysmal vertigo	0.010	0.990	0.000
D32.1 Spinal meninges	0.000	0.990	0.010
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.990	0.010
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.991	0.009
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.991	0.009
M34 Systemic sclerosis	0.009	0.991	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.991	0.009
M22.0 Recurrent dislocation of patella	0.009	0.991	0.000
F30-F39 Mood [affective] disorders	0.000	0.991	0.009
F33.8 Other recurrent depressive disorders	0.000	0.991	0.009
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.991	0.009
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.991	0.009
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.991	0.009
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.991	0.008
G61.0 Guillain-Barre syndrome	0.008	0.992	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.992	0.008
F31.8 Other bipolar affective disorders	0.000	0.992	0.008
F30.0 Hypomania	0.000	0.992	0.008
T93 Sequelae of injuries of lower limb	0.008	0.992	0.000
Z97.8 Presence of other specified devices	0.000	0.992	0.008
F31.7 Bipolar affective disorder, currently in remission	0.000	0.992	0.008
F30 Manic episode	0.000	0.992	0.008
M34.1 CR(E)ST syndrome	0.008	0.992	0.000
M34.8 Other forms of systemic sclerosis	0.008	0.992	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.992	0.008
M22.10 Recurrent subluxation of patella, unspecified knee	0.007	0.993	0.000
T93.0 Sequelae of open wound of lower limb	0.007	0.993	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.007	0.993	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.007	0.993	0.000
M34.0 Progressive systemic sclerosis	0.007	0.993	0.000
F39 Unspecified mood [affective] disorder	0.000	0.993	0.007
F38 Other mood [affective] disorders	0.000	0.993	0.007
J30.1 Allergic rhinitis due to pollen	0.007	0.993	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.006	0.994	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.994	0.006
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.994	0.006
Z97.4 Presence of external hearing-aid	0.000	0.994	0.006
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.006	0.994	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.006	0.994	0.000
F30.8 Other manic episodes	0.000	0.994	0.006
Z29.2 Other prophylactic chemotherapy	0.006	0.994	0.000
T93.1 Sequelae of fracture of femur	0.006	0.994	0.000
K66 Other disorders of peritoneum	0.006	0.994	0.000
F34 Persistent mood [affective] disorders	0.000	0.995	0.005
F30.2 Mania with psychotic symptoms	0.000	0.995	0.005
F30.9 Manic episode, unspecified	0.000	0.995	0.005
J30.4 Allergic rhinitis, unspecified	0.005	0.995	0.000
N48.4 Impotence of organic origin	0.000	0.995	0.005
F38.8 Other specified mood [affective] disorders	0.000	0.995	0.005
F38.1 Other recurrent mood [affective] disorders	0.000	0.995	0.005
F38.0 Other single mood [affective] disorders	0.000	0.995	0.005
J30 Vasomotor and allergic rhinitis	0.005	0.995	0.000
I85.0 Oesophageal varices with bleeding	0.005	0.995	0.000
F30.1 Mania without psychotic symptoms	0.000	0.995	0.005
M20-M25 Other joint disorders	0.004	0.996	0.000
M30 Polyarteritis nodosa and related conditions	0.004	0.996	0.000
K66.9 Disorder of peritoneum, unspecified	0.004	0.996	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.996	0.004
F34.8 Other persistent mood [affective] disorders	0.000	0.996	0.004
F34.0 Cyclothymia	0.000	0.996	0.004
J30.3 Other allergic rhinitis	0.004	0.996	0.000
M32 Systemic lupus erythematosus	0.004	0.996	0.000
K66.1 Haemoperitoneum	0.004	0.996	0.000
T93.2 Sequelae of other fractures of lower limb	0.004	0.996	0.000
E89.0 Postprocedural hypothyroidism	0.004	0.996	0.000
H81 Disorders of vestibular function	0.004	0.996	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.996	0.004
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.004	0.996	0.000
M30.0 Polyarteritis nodosa	0.004	0.996	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.004	0.996	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.004	0.996	0.000
G61 Inflammatory polyneuropathy	0.004	0.996	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.004	0.996	0.000
J30.2 Other seasonal allergic rhinitis	0.004	0.996	0.000
M22.4 Chondromalacia patellae	0.004	0.996	0.000
J30.0 Vasomotor rhinitis	0.003	0.996	0.000
K66.8 Other specified disorders of peritoneum	0.004	0.996	0.000
H81.4 Vertigo of central origin	0.003	0.996	0.000
M32.8 Other forms of systemic lupus erythematosus	0.003	0.996	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.996	0.004
H81.3 Other peripheral vertigo	0.003	0.997	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.997	0.003
M30.8 Other conditions related to polyarteritis nodosa	0.003	0.997	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.003	0.997	0.000
M30.2 Juvenile polyarteritis	0.003	0.997	0.000
M25.71 Osteophyte (Shoulder region)	0.000	0.997	0.003
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.003	0.997	0.000
N32.9 Bladder disorder, unspecified	0.003	0.997	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.003	0.997	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.003	0.997	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.003	0.997	0.000
M33 Dermatopolymyositis	0.003	0.997	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.003	0.997	0.000
Q63.0 Accessory kidney	0.000	0.997	0.003
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.997	0.003
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.997	0.003
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.997	0.003
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.997	0.003
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.997	0.003
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.997	0.003
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.997	0.003
M31.9 Necrotising vasculopathy, unspecified	0.003	0.997	0.000
M31 Other necrotising vasculopathies	0.003	0.997	0.000
G61.1 Serum neuropathy	0.003	0.997	0.000
F34.1 Dysthymia	0.001	0.997	0.002
H81.8 Other disorders of vestibular function	0.003	0.997	0.000
H81.2 Vestibular neuronitis	0.003	0.997	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.003	0.997	0.000
M31.7 Microscopic polyangiitis	0.003	0.997	0.000
G61.8 Other inflammatory polyneuropathies	0.003	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.003	0.997	0.000
H81.9 Disorder of vestibular function, unspecified	0.003	0.997	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.003	0.997	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.002	0.997	0.000
M36.3 Arthropathy in other blood disorders	0.002	0.997	0.000
M36.2 Haemophilic arthropathy	0.002	0.997	0.000
M36.1 Arthropathy in neoplastic disease	0.002	0.997	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.002	0.997	0.000
M21 Other acquired deformities of limbs	0.003	0.997	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.997	0.003
M33.9 Dermatopolymyositis, unspecified	0.002	0.997	0.000
M33.1 Other dermatomyositis	0.003	0.997	0.000
M33.0 Juvenile dermatomyositis	0.002	0.997	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.002	0.997	0.000
H80 Otosclerosis	0.003	0.997	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.997	0.000
T78.3 Angioneurotic oedema	0.000	0.997	0.003
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.997	0.003
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.002	0.997	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.003	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.002	0.997	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.003	0.997	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.003	0.997	0.000
M35 Other systemic involvement of connective tissue	0.003	0.997	0.000
D13.1 Stomach	0.003	0.997	0.000
E13.9 Without complications	0.000	0.997	0.003
M89.0 Algoneurodystrophy	0.003	0.997	0.000
D43.2 Brain, unspecified	0.000	0.997	0.003
H80-H83 Diseases of inner ear	0.003	0.997	0.000
I49.3 Ventricular premature depolarisation	0.003	0.997	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.997	0.000
M35.0 Sicca syndrome [Sjogren]	0.003	0.997	0.000
M24 Other specific joint derangements	0.003	0.997	0.000
J80 Adult respiratory distress syndrome	0.000	0.998	0.002
M31.2 Lethal midline granuloma	0.002	0.998	0.000
M31.0 Hypersensitivity angiitis	0.002	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.002	0.998	0.000
M33.2 Polymyositis	0.002	0.998	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.002	0.998	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.998	0.002
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.002	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.002	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.002	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.002	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.002	0.998	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
M21.7 Unequal limb length (acquired)	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.002	0.998	0.000
D33.2 Brain, unspecified	0.000	0.998	0.002
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
M35.7 Hypermobility syndrome	0.002	0.998	0.000
T17.2 Foreign body in pharynx	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
M24.7 Protrusio acetabuli	0.002	0.998	0.000
M24.6 Ankylosis of joint	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
M21.8 Other specified acquired deformities of limbs	0.002	0.998	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
H80.8 Other otosclerosis	0.002	0.998	0.000
H80.2 Cochlear otosclerosis	0.002	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.002	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.000	0.998	0.002
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
M21.2 Flexion deformity	0.002	0.998	0.000
I24.8 Other forms of acute ischaemic heart disease	0.002	0.998	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.002	0.998	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.002	0.998	0.000
M35.5 Multifocal fibrosclerosis	0.002	0.998	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
Z29 Need for other prophylactic measures	0.002	0.998	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
M35.2 Behcet's disease	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.002	0.998	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
H35.2 Other proliferative retinopathy	0.002	0.998	0.000
M24.9 Joint derangement, unspecified	0.002	0.998	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.998	0.002
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
M21.3 Wrist or foot drop (acquired)	0.002	0.998	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.002	0.998	0.000
M24.64 Ankylosis of joint (Hand)	0.002	0.998	0.000
M24.5 Contracture of joint	0.002	0.998	0.000
M35.1 Other overlap syndromes	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
F32 Depressive episode	0.000	0.998	0.002
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
H35.6 Retinal haemorrhage	0.002	0.998	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.002	0.998	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.002	0.998	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.002	0.998	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.002	0.998	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.002	0.998	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.002	0.998	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.002	0.998	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.002	0.998	0.000
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.000	0.998	0.002
M88 Paget's disease of bone [osteitis deformans]	0.000	0.998	0.002
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.002	0.998	0.000
M21.78 Unequal limb length (acquired)-Other	0.002	0.998	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.002	0.998	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.002	0.998	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.002	0.998	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.002	0.998	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.002	0.998	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.998	0.002
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.002	0.998	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.002	0.998	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.002	0.998	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.002	0.998	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.002	0.998	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.002	0.998	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.002	0.998	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.002	0.998	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.998	0.002
H74.4 Polyp of middle ear	0.002	0.998	0.000
M21.4 Flat foot [pes planus] (acquired)	0.001	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.998	0.002
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.002	0.998	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.002	0.998	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.002	0.998	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.002	0.998	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.002	0.998	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.002	0.998	0.000
M24.79 Protrusio acetabuli-Site unspec	0.002	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.002	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.002	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.002	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.002	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.002	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.002	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.002	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.002	0.998	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.002	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.002	0.998	0.000
M24.63 Ankylosis of joint (Forearm)	0.002	0.998	0.000
M24.62 Ankylosis of joint (Upper arm)	0.002	0.998	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.002	0.998	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
F32.8 Other depressive episodes	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.002	0.998	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.002	0.998	0.000
K65-K67 Diseases of peritoneum	0.002	0.998	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.002	0.998	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.002	0.998	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.998	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.002	0.998	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.002	0.998	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.002	0.998	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.002	0.998	0.000
M21.28 Flexion deformity (Other)	0.002	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.002	0.998	0.000
M21.21 Flexion deformity (Shoulder region)	0.002	0.998	0.000
M21.20 Flexion deformity (Multiple sites)	0.002	0.998	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.002	0.998	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.002	0.998	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.002	0.998	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.002	0.998	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.002	0.998	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.002	0.998	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.002	0.998	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.002	0.998	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.002	0.998	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.998	0.000
H35.4 Peripheral retinal degeneration	0.002	0.998	0.000
M35.8 Other specified systemic involvement of connective tissue	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.998	0.002
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
G71.1 Myotonic disorders	0.000	0.998	0.002
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
Z29.9 Prophylactic measure, unspecified	0.002	0.998	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.002	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.002	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.002	0.998	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.002	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.002	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.002	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.002	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.000	0.998	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.998	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.998	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.998	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.998	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.998	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.998	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.002	0.998	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
C15.3 Upper third of oesophagus	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.998	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
D16.1 Short bones of upper limb	0.002	0.998	0.000
M89.8 Other specified disorders of bone	0.002	0.998	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.002	0.998	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.001	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
J20.9 Acute bronchitis, unspecified	0.000	0.998	0.002
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.001	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.001	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.001	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
K56.2 Volvulus	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.002	0.998	0.000
R57.2 Septic shock	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
B91 Sequelae of poliomyelitis	0.002	0.998	0.000
C45 Mesothelioma	0.000	0.998	0.002
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
M88.8 Paget's disease of other bones	0.000	0.998	0.001
M88.0 Paget's disease of skull	0.000	0.998	0.001
Z50.0 Cardiac rehabilitation	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.002	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
H47.2 Optic atrophy	0.000	0.998	0.002
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.998	0.002
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
Z29.0 Isolation	0.002	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.002	0.998	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.001	0.998	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.001	0.998	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.001	0.998	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.001	0.998	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.001	0.998	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.001	0.998	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.001	0.998	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.001	0.998	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.001	0.998	0.000
M21.1 Varus deformity, not elsewhere classified	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
M89 Other disorders of bone	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations