TreeWAS – Variant ID: rs10483853

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M51 Other intervertebral disk disorders	0.059	0.941	0.000
M50-M54 Other dorsopathies	0.058	0.942	0.000
M54 Dorsalgia	0.056	0.944	0.000
M53 Other dorsopathies, not elsewhere classified	0.055	0.945	0.000
M51.9 Intervertebral disk disorder, unspecified	0.055	0.945	0.000
M54.9 Dorsalgia, unspecified	0.055	0.945	0.000
M51.2 Other specified intervertebral disk displacement	0.054	0.946	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.053	0.947	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.948	0.052
M54.5 Low back pain	0.052	0.948	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.051	0.949	0.000
M54.56 Low back pain (Lumbar region)	0.051	0.949	0.000
M54.57 Low back pain (Lumbosacral region)	0.050	0.950	0.000
M81.9 Osteoporosis, unspecified	0.000	0.951	0.049
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.049	0.951	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.048	0.952	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.047	0.953	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.047	0.953	0.000
M50 Cervical disk disorders	0.047	0.953	0.000
M51.3 Other specified intervertebral disk degeneration	0.046	0.954	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.955	0.045
M81.98 Osteoporosis, unspecified (Other)	0.000	0.955	0.045
M53.8 Other specified dorsopathies	0.044	0.956	0.000
M50.3 Other cervical disk degeneration	0.044	0.956	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.043	0.957	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.042	0.958	0.000
M51.4 Schmorl's nodes	0.042	0.958	0.000
M54.8 Other dorsalgia	0.041	0.959	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.041	0.959	0.000
M54.4 Lumbago with sciatica	0.041	0.959	0.000
M54.0 Panniculitis affecting regions of neck and back	0.040	0.960	0.000
M53.9 Dorsopathy, unspecified	0.040	0.960	0.000
M53.2 Spinal instabilities	0.040	0.960	0.000
M53.1 Cervicobrachial syndrome	0.040	0.960	0.000
M53.0 Cervicocranial syndrome	0.040	0.960	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.039	0.961	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.039	0.961	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.039	0.961	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.038	0.961	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.038	0.961	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.038	0.962	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.038	0.962	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.038	0.962	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.038	0.962	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.038	0.962	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.038	0.962	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.038	0.962	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.038	0.962	0.000
M54.2 Cervicalgia	0.038	0.962	0.000
M54.54 Low back pain-Thoracic	0.037	0.963	0.000
M54.53 Low back pain-Cervicothoracic	0.037	0.963	0.000
M54.52 Low back pain-Cervical	0.037	0.963	0.000
M54.51 Low back pain-Occipit-atl-axl	0.037	0.963	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.037	0.963	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.963	0.036
M53.82 Other specified dorsopathies (Cervical region)	0.036	0.964	0.000
M50.8 Other cervical disk disorders	0.036	0.964	0.000
M54.6 Pain in thoracic spine	0.035	0.965	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.965	0.035
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.965	0.035
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.965	0.035
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.965	0.035
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.965	0.035
M54.50 Low back pain (Multiple sites in spine)	0.034	0.965	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.034	0.966	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.966	0.034
M54.49 Lumbago with sciatica (Site unspecified)	0.034	0.966	0.000
M50.1 Cervical disk disorder with radiculopathy	0.034	0.966	0.000
M54.55 Low back pain (Thoracolumbar region)	0.033	0.967	0.000
M54.3 Sciatica	0.033	0.967	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.033	0.967	0.000
M53.89 Other specified dorsopathies (Site unspecified)	0.032	0.968	0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.032	0.968	0.000
M53.87 Other specified dorsopathies (Lumbosacral region)	0.032	0.968	0.000
M53.86 Other specified dorsopathies (Lumbar region)	0.032	0.968	0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.032	0.968	0.000
M53.84 Other specified dorsopathies (Thoracic region)	0.032	0.968	0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.032	0.968	0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.032	0.968	0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.032	0.968	0.000
M50.0 Cervical disk disorder with myelopathy	0.031	0.969	0.000
M50.9 Cervical disk disorder, unspecified	0.031	0.969	0.000
M54.89 Other dorsalgia (Site unspecified)	0.031	0.969	0.000
M51.8 Other specified intervertebral disk disorders	0.031	0.969	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.030	0.969	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.030	0.969	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.030	0.970	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.030	0.970	0.000
M54.86 Other dorsalgia (Lumbar region)	0.030	0.970	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.030	0.970	0.000
M54.84 Other dorsalgia (Thoracic region)	0.030	0.970	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.030	0.970	0.000
M54.82 Other dorsalgia (Cervical region)	0.030	0.970	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.030	0.970	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.030	0.970	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.029	0.971	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.029	0.971	0.000
M54.44 Lumbago with sciatica-Thoracic	0.029	0.971	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.029	0.971	0.000
M54.42 Lumbago with sciatica-Cervical	0.029	0.971	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.029	0.971	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.029	0.971	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.029	0.971	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.029	0.971	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.029	0.971	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.029	0.971	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.029	0.971	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.029	0.971	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.029	0.971	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.029	0.971	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.029	0.971	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.029	0.971	0.000
M53.09 Cervicocranial syndrome-Site unspe	0.029	0.971	0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.029	0.971	0.000
M53.07 Cervicocranial syndrome-Lumbosacral	0.029	0.971	0.000
M53.06 Cervicocranial syndrome-Lumbar	0.029	0.971	0.000
M53.05 Cervicocranial syndrome-Thoracolumbar	0.029	0.971	0.000
M53.04 Cervicocranial syndrome-Thoracic	0.029	0.971	0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.029	0.971	0.000
M53.02 Cervicocranial syndrome (Cervical region)	0.029	0.971	0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.029	0.971	0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.029	0.971	0.000
M53.19 Cervicobrachial syndrome-Site unspe	0.029	0.971	0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.029	0.971	0.000
M53.17 Cervicobrachial syndrome-Lumbosacral	0.029	0.971	0.000
M53.16 Cervicobrachial syndrome-Lumbar	0.029	0.971	0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.029	0.971	0.000
M53.14 Cervicobrachial syndrome-Thoracic	0.029	0.971	0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.029	0.971	0.000
M53.12 Cervicobrachial syndrome (Cervical region)	0.029	0.971	0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.029	0.971	0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.029	0.971	0.000
M53.29 Spinal instabilities (Site unspecified)	0.029	0.971	0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.029	0.971	0.000
M53.27 Spinal instabilities (Lumbosacral region)	0.029	0.971	0.000
M53.26 Spinal instabilities (Lumbar region)	0.029	0.971	0.000
M53.25 Spinal instabilities (Thoracolumbar region)	0.029	0.971	0.000
M53.24 Spinal instabilities (Thoracic region)	0.029	0.971	0.000
M53.23 Spinal instabilities (Cervicothoracic region)	0.029	0.971	0.000
M53.22 Spinal instabilities (Cervical region)	0.029	0.971	0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.029	0.971	0.000
M53.20 Spinal instabilities (Multiple sites in spine)	0.029	0.971	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.029	0.971	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.029	0.971	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.029	0.971	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.029	0.971	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.029	0.971	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.029	0.971	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.029	0.971	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.029	0.971	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.029	0.971	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.029	0.971	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.027	0.973	0.000
M54.27 Cervicalgia-Lumbosacral	0.027	0.973	0.000
M54.26 Cervicalgia-Lumbar	0.027	0.973	0.000
M54.25 Cervicalgia-Thoracolumbar	0.027	0.973	0.000
M54.24 Cervicalgia-Thoracic	0.027	0.973	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.027	0.973	0.000
M54.20 Cervicalgia-Mult site	0.027	0.973	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.027	0.973	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.026	0.974	0.000
M54.69 Pain in thoracic spine-Site unspe	0.025	0.974	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.025	0.974	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.025	0.974	0.000
M54.66 Pain in thoracic spine-Lumbar	0.025	0.974	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.025	0.974	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.025	0.974	0.000
M54.62 Pain in thoracic spine-Cervical	0.025	0.974	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.025	0.974	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.025	0.974	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.026	0.974	0.000
M54.36 Sciatica (Lumbar region)	0.025	0.974	0.000
M54.29 Cervicalgia-Site unspe	0.025	0.975	0.000
M54.1 Radiculopathy	0.024	0.976	0.000
M54.35 Sciatica (Thoracolumbar region)	0.024	0.976	0.000
M54.34 Sciatica-Thoracic	0.024	0.976	0.000
M54.33 Sciatica-Cervicothoracic	0.024	0.976	0.000
M54.32 Sciatica-Cervical	0.024	0.976	0.000
M54.31 Sciatica-Occipit-atl-axl	0.024	0.976	0.000
M54.30 Sciatica (Multiple sites in spine)	0.024	0.976	0.000
M54.59 Low back pain (Site unspecified)	0.023	0.977	0.000
M50.2 Other cervical disk displacement	0.022	0.978	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.021	0.979	0.000
M81 Osteoporosis without pathological fracture	0.001	0.980	0.019
M54.39 Sciatica (Site unspecified)	0.019	0.981	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.017	0.982	0.000
M54.14 Radiculopathy (Thoracic region)	0.017	0.982	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.017	0.982	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.017	0.982	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.017	0.982	0.000
M54.37 Sciatica (Lumbosacral region)	0.017	0.982	0.000
M54.12 Radiculopathy (Cervical region)	0.017	0.983	0.000
M54.22 Cervicalgia (Cervical region)	0.017	0.983	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.016	0.983	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.016	0.983	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.016	0.984	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.984	0.016
M54.19 Radiculopathy (Site unspecified)	0.015	0.985	0.000
M81.0 Postmenopausal osteoporosis	0.001	0.985	0.014
M81.8 Other osteoporosis	0.001	0.985	0.014
M81.6 Localised osteoporosis [Lequesne]	0.001	0.985	0.014
M81.5 Idiopathic osteoporosis	0.001	0.985	0.014
M81.3 Postsurgical malabsorption osteoporosis	0.001	0.985	0.014
M81.1 Postoophorectomy osteoporosis	0.001	0.985	0.014
N83.0 Follicular cyst of ovary	0.014	0.986	0.000
M81.2 Osteoporosis of disuse	0.001	0.986	0.013
Z03.3 Observation for suspected nervous system disorder	0.014	0.986	0.000
M81.4 Drug-induced osteoporosis	0.001	0.987	0.013
N83.2 Other and unspecified ovarian cysts	0.013	0.987	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.013	0.987	0.000
N83.1 Corpus luteum cyst	0.012	0.988	0.000
H93.1 Tinnitus	0.000	0.988	0.012
M54.16 Radiculopathy (Lumbar region)	0.012	0.988	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.001	0.989	0.011
M81.08 Postmenopausal osteoporosis (Other)	0.001	0.989	0.010
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.001	0.989	0.010
M81.06 Postmenopausal osteoporosis (Lower leg)	0.001	0.989	0.010
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.001	0.989	0.010
M81.04 Postmenopausal osteoporosis (Hand)	0.001	0.989	0.010
M81.03 Postmenopausal osteoporosis (Forearm)	0.001	0.989	0.010
M81.02 Postmenopausal osteoporosis (Upper arm)	0.001	0.989	0.010
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.001	0.989	0.010
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.001	0.989	0.010
S72.0 Fracture of neck of femur	0.000	0.989	0.011
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.011	0.989	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.001	0.989	0.010
M81.18 Postoophorectomy osteoporosis (Other)	0.001	0.989	0.010
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.001	0.989	0.010
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.001	0.989	0.010
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.001	0.989	0.010
M81.14 Postoophorectomy osteoporosis (Hand)	0.001	0.989	0.010
M81.13 Postoophorectomy osteoporosis (Forearm)	0.001	0.989	0.010
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.001	0.989	0.010
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.001	0.989	0.010
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.001	0.989	0.010
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.001	0.989	0.010
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.001	0.989	0.010
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.001	0.989	0.010
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.001	0.989	0.010
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.001	0.989	0.010
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.001	0.989	0.010
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.001	0.989	0.010
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.001	0.989	0.010
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.001	0.989	0.010
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.001	0.989	0.010
M81.59 Idiopathic osteoporosis (Site unspecified)	0.001	0.989	0.010
M81.58 Idiopathic osteoporosis (Other)	0.001	0.989	0.010
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.001	0.989	0.010
M81.56 Idiopathic osteoporosis (Lower leg)	0.001	0.989	0.010
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.001	0.989	0.010
M81.54 Idiopathic osteoporosis (Hand)	0.001	0.989	0.010
M81.53 Idiopathic osteoporosis (Forearm)	0.001	0.989	0.010
M81.52 Idiopathic osteoporosis (Upper arm)	0.001	0.989	0.010
M81.51 Idiopathic osteoporosis (Shoulder region)	0.001	0.989	0.010
M81.50 Idiopathic osteoporosis (Multiple sites)	0.001	0.989	0.010
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.001	0.989	0.010
M81.68 Localized osteoporosis [Lequesne] (Other)	0.001	0.989	0.010
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.001	0.989	0.010
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.001	0.989	0.010
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.001	0.989	0.010
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.001	0.989	0.010
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.001	0.989	0.010
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.001	0.989	0.010
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.001	0.989	0.010
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.001	0.989	0.010
M81.89 Other osteoporosis (Site unspecified)	0.001	0.989	0.010
M81.88 Other osteoporosis (Other)	0.001	0.989	0.010
M81.87 Other osteoporosis (Ankle and foot)	0.001	0.989	0.010
M81.86 Other osteoporosis (Lower leg)	0.001	0.989	0.010
M81.85 Other osteoporosis (Pelvic region and thigh)	0.001	0.989	0.010
M81.84 Other osteoporosis (Hand)	0.001	0.989	0.010
M81.83 Other osteoporosis (Forearm)	0.001	0.989	0.010
M81.82 Other osteoporosis (Upper arm)	0.001	0.989	0.010
M81.81 Other osteoporosis (Shoulder region)	0.001	0.989	0.010
M81.80 Other osteoporosis (Multiple sites)	0.001	0.989	0.010
Y43.3 Other antineoplastic drugs	0.011	0.989	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.990	0.010
N83.3 Acquired atrophy of ovary and Fallopian tube	0.010	0.990	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.001	0.990	0.009
M81.28 Osteoporosis of disuse (Other)	0.001	0.990	0.009
M81.27 Osteoporosis of disuse (Ankle and foot)	0.001	0.990	0.009
M81.26 Osteoporosis of disuse (Lower leg)	0.001	0.990	0.009
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.001	0.990	0.009
M81.24 Osteoporosis of disuse (Hand)	0.001	0.990	0.009
M81.23 Osteoporosis of disuse (Forearm)	0.001	0.990	0.009
M81.22 Osteoporosis of disuse (Upper arm)	0.001	0.990	0.009
M81.21 Osteoporosis of disuse (Shoulder region)	0.001	0.990	0.009
M81.48 Drug-induced osteoporosis (Other)	0.001	0.990	0.009
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.001	0.990	0.009
M81.46 Drug-induced osteoporosis (Lower leg)	0.001	0.990	0.009
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.001	0.990	0.009
M81.44 Drug-induced osteoporosis (Hand)	0.001	0.990	0.009
M81.43 Drug-induced osteoporosis (Forearm)	0.001	0.990	0.009
M81.42 Drug-induced osteoporosis (Upper arm)	0.001	0.990	0.009
M81.41 Drug-induced osteoporosis (Shoulder region)	0.001	0.990	0.009
N83.7 Haematoma of broad ligament	0.009	0.991	0.000
N83.6 Haematosalpinx	0.009	0.991	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.009	0.991	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.001	0.991	0.008
S32.50 Fracture of pubis (closed)	0.008	0.992	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.992	0.008
S32.5 Fracture of pubis	0.008	0.992	0.000
Y43 Primarily systemic agents	0.008	0.992	0.000
S32 Fracture of lumbar spine and pelvis	0.008	0.992	0.000
S32.10 Fracture of sacrum (closed)	0.008	0.992	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.008	0.992	0.000
S32.1 Fracture of sacrum	0.008	0.992	0.000
S72 Fracture of femur	0.000	0.993	0.007
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.993	0.006
Y43.1 Antineoplastic antimetabolites	0.007	0.993	0.000
Y43.4 Immunosuppressive agents	0.007	0.993	0.000
S72.3 Fracture of shaft of femur	0.000	0.993	0.007
S02.40 Fracture of malar and maxillary bones (closed)	0.007	0.993	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.007	0.993	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.993	0.007
S32.3 Fracture of ilium	0.007	0.993	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.994	0.006
S72.1 Pertrochanteric fracture	0.000	0.994	0.006
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.006	0.994	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.006	0.994	0.000
Z90.2 Acquired absence of lung [part of]	0.000	0.994	0.006
S32.0 Fracture of lumbar vertebra	0.006	0.994	0.000
M80-M85 Disorders of bone density and structure	0.002	0.994	0.004
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.006	0.994	0.000
C67.9 Bladder, unspecified	0.000	0.994	0.006
Y43.0 Antiallergic and antiemetic drugs	0.006	0.994	0.000
S32.51 Fracture of pubis (open)	0.006	0.994	0.000
Y43.9 Primarily systemic agent, unspecified	0.006	0.994	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.006	0.994	0.000
Y43.6 Enzymes, not elsewhere classified	0.006	0.994	0.000
Y43.5 Acidifying and alkalising agents	0.006	0.994	0.000
Y43.2 Antineoplastic natural products	0.006	0.994	0.000
S32.2 Fracture of coccyx	0.006	0.994	0.000
S32.30 Fracture of ilium (closed)	0.006	0.994	0.000
S32.4 Fracture of acetabulum	0.006	0.994	0.000
S32.11 Fracture of sacrum (open)	0.006	0.994	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.994	0.006
S72.9 Fracture of femur, part unspecified	0.000	0.994	0.005
S72.7 Multiple fractures of femur	0.000	0.994	0.005
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
T43.2 Other and unspecified antidepressants	0.005	0.995	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.995	0.005
S72.31 Fracture of shaft of femur (open)	0.000	0.995	0.005
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.005	0.995	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.005	0.995	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.005	0.995	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.005	0.995	0.000
S32.31 Fracture of ilium (open)	0.005	0.995	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
S72.4 Fracture of lower end of femur	0.000	0.995	0.005
S72.8 Fractures of other parts of femur	0.000	0.995	0.005
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
Y60.0 During surgical operation	0.005	0.995	0.000
T43.6 Psychostimulants with abuse potential	0.005	0.995	0.000
M84 Disorders of continuity of bone	0.001	0.995	0.004
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.005	0.995	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.995	0.005
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.005	0.995	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.005	0.995	0.000
S32.01 Fracture of lumbar vertebra (open)	0.005	0.995	0.000
M83 Adult osteomalacia	0.001	0.995	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.005	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.004	0.995	0.000
S32.21 Fracture of coccyx (open)	0.004	0.995	0.000
S32.20 Fracture of coccyx (closed)	0.004	0.995	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.996	0.004
I42.0 Dilated cardiomyopathy	0.000	0.996	0.004
S32.41 Fracture of acetabulum (open)	0.004	0.996	0.000
S72.2 Subtrochanteric fracture	0.000	0.996	0.004
M82 Osteoporosis in diseases classified elsewhere	0.001	0.996	0.003
H18.6 Keratoconus	0.004	0.996	0.000
B34.9 Viral infection, unspecified	0.004	0.996	0.000
S32.40 Fracture of acetabulum (closed)	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.996	0.004
S72.70 Multiple fractures of femur (closed)	0.000	0.996	0.004
S72.91 Fracture of femur, part unspecified (open)	0.000	0.996	0.004
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.996	0.004
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.996	0.004
B34.8 Other viral infections of unspecified site	0.004	0.996	0.000
M66.2 Spontaneous rupture of extensor tendons	0.004	0.996	0.000
S02.4 Fracture of malar and maxillary bones	0.004	0.996	0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.004	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.004	0.996	0.000
H93.8 Other specified disorders of ear	0.000	0.996	0.004
T43.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
H18 Other disorders of cornea	0.004	0.996	0.000
F33.9 Recurrent depressive disorder, unspecified	0.004	0.996	0.000
H93.3 Disorders of acoustic nerve	0.000	0.996	0.004
H93.2 Other abnormal auditory perceptions	0.000	0.996	0.004
H93.0 Degenerative and vascular disorders of ear	0.000	0.996	0.004
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.996	0.004
N03.9 Unspecified	0.004	0.996	0.000
E34 Other endocrine disorders	0.004	0.996	0.000
H93.9 Disorder of ear, unspecified	0.000	0.996	0.004
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
B34 Viral infection of unspecified site	0.004	0.996	0.000
K12.1 Other forms of stomatitis	0.004	0.996	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.996	0.004
M85 Other disorders of bone density and structure	0.001	0.996	0.003
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.004	0.996	0.000
S72.81 Fractures of other parts of femur (open)	0.000	0.996	0.004
C67 Malignant neoplasm of bladder	0.000	0.996	0.004
M05 Seropositive rheumatoid arthritis	0.004	0.996	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.996	0.004
H18.2 Other corneal oedema	0.004	0.996	0.000
M62 Other disorders of muscle	0.004	0.996	0.000
M84.9 Disorder of continuity of bone, unspecified	0.001	0.996	0.003
M84.8 Other disorders of continuity of bone	0.001	0.996	0.003
M84.2 Delayed union of fracture	0.001	0.996	0.003
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.996	0.004
H18.1 Bullous keratopathy	0.004	0.996	0.000
M66 Spontaneous rupture of synovium and tendon	0.004	0.996	0.000
M60-M63 Disorders of muscles	0.004	0.996	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.004	0.996	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.004	0.996	0.000
C67.5 Bladder neck	0.000	0.996	0.004
M80 Osteoporosis with pathological fracture	0.002	0.996	0.002
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
M83.9 Adult osteomalacia, unspecified	0.001	0.996	0.003
M83.8 Other adult osteomalacia	0.001	0.996	0.003
M83.5 Other drug-induced osteomalacia in adults	0.001	0.996	0.003
M83.4 Aluminum bone disease	0.001	0.996	0.003
M83.3 Adult osteomalacia due to malnutrition	0.001	0.996	0.003
M83.2 Adult osteomalacia due to malabsorption	0.001	0.996	0.003
M83.1 Senile osteomalacia	0.001	0.996	0.003
M83.0 Puerperal osteomalacia	0.001	0.996	0.003
M66.3 Spontaneous rupture of flexor tendons	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.004	0.996	0.000
M84.3 Stress fracture, not elsewhere classified	0.001	0.996	0.003
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.996	0.003
C67.3 Anterior wall of bladder	0.000	0.996	0.004
C92.0 Acute myeloid leukaemia	0.004	0.996	0.000
H18.4 Corneal degeneration	0.003	0.996	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.996	0.004
I46.9 Cardiac arrest, unspecified	0.000	0.996	0.004
M62.8 Other specified disorders of muscle	0.003	0.996	0.000
H72 Perforation of tympanic membrane	0.004	0.996	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.996	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.004	0.996	0.000
Z51.3 Blood transfusion without reported diagnosis	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.997	0.003
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.997	0.003
S72.41 Fracture of lower end of femur (open)	0.000	0.997	0.003
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.003	0.997	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
S72.21 Subtrochanteric fracture (open)	0.000	0.997	0.003
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.997	0.002
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.997	0.002
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.997	0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
C67.1 Dome of bladder	0.000	0.997	0.003
M84.4 Pathological fracture, not elsewhere classified	0.001	0.997	0.002
I42.2 Other hypertrophic cardiomyopathy	0.000	0.997	0.003
S02.41 Fracture of malar and maxillary bones (open)	0.003	0.997	0.000
S72.80 Fractures of other parts of femur (closed)	0.000	0.997	0.003
M60 Myositis	0.003	0.997	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.003	0.997	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.003	0.997	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.003	0.997	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.003	0.997	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.003	0.997	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.003	0.997	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.003	0.997	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.003	0.997	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.003	0.997	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.997	0.003
I42 Cardiomyopathy	0.000	0.997	0.003
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.003	0.997	0.000
H18.7 Other corneal deformities	0.003	0.997	0.000
H18.3 Changes in corneal membranes	0.003	0.997	0.000
M84.0 Malunion of fracture	0.001	0.997	0.002
N28.9 Disorder of kidney and ureter, unspecified	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.003	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
M65-M68 Disorders of synovium and tendon	0.003	0.997	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.997	0.003
C67.8 Overlapping lesion of bladder	0.000	0.997	0.003
E34.0 Carcinoid syndrome	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations