TreeWAS – Variant ID: rs10488029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T40.2 Other opioids	0.025	0.975	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.024	0.976	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.022	0.978	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.020	0.980	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.019	0.980	0.000
T40.4 Other synthetic narcotics	0.019	0.981	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.019	0.981	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.019	0.981	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.019	0.981	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.019	0.981	0.000
T40.6 Other and unspecified narcotics	0.018	0.982	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.018	0.982	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.018	0.982	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.018	0.982	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.017	0.983	0.000
T40.8 Lysergide [LSD]	0.017	0.983	0.000
T40.7 Cannabis (derivatives)	0.017	0.983	0.000
T40.5 Cocaine	0.017	0.983	0.000
T40.3 Methadone	0.017	0.983	0.000
T40.1 Heroin	0.017	0.983	0.000
T40.0 Opium	0.017	0.983	0.000
T38.1 Thyroid hormones and substitutes	0.017	0.983	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.016	0.984	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.016	0.984	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.016	0.984	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.016	0.984	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.016	0.984	0.000
T36 Poisoning by systemic antibiotics	0.015	0.984	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.015	0.985	0.000
T38.9 Other and unspecified hormone antagonists	0.015	0.985	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.015	0.985	0.000
T38.7 Androgens and anabolic congeners	0.015	0.985	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.015	0.985	0.000
T38.5 Other oestrogens and progestogens	0.015	0.985	0.000
T38.4 Oral contraceptives	0.015	0.985	0.000
T38.2 Antithyroid drugs	0.015	0.985	0.000
T38.0 Glucocorticoids and synthetic analogues	0.015	0.985	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.015	0.985	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.015	0.985	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.014	0.986	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.014	0.986	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.014	0.986	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.014	0.986	0.000
T47.7 Emetics	0.014	0.986	0.000
T47.6 Antidiarrhoeal drugs	0.014	0.986	0.000
T47.5 Digestants	0.014	0.986	0.000
T47.4 Other laxatives	0.014	0.986	0.000
T47.3 Saline and osmotic laxatives	0.014	0.986	0.000
T47.2 Stimulant laxatives	0.014	0.986	0.000
T47.0 Histamine H(2)-receptor antagonists	0.014	0.986	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.014	0.986	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.014	0.986	0.000
T42.3 Barbiturates	0.014	0.986	0.000
T42.2 Succinimides and oxazolidinediones	0.014	0.986	0.000
T42.1 Iminostilbenes	0.014	0.986	0.000
T42.0 Hydantoin derivatives	0.014	0.986	0.000
K29.6 Other gastritis	0.000	0.986	0.014
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.014	0.986	0.000
T39.4 Antirheumatics, not elsewhere classified	0.014	0.986	0.000
T39.2 Pyrazolone derivatives	0.014	0.986	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.013	0.986	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.013	0.987	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.013	0.987	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.013	0.987	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.013	0.987	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.013	0.987	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.013	0.987	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.013	0.987	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.013	0.987	0.000
T44.0 Anticholinesterase agents	0.013	0.987	0.000
T39.0 Salicylates	0.012	0.988	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.011	0.988	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.011	0.988	0.000
T37.5 Antiviral drugs	0.011	0.988	0.000
T37.4 Anthelminthics	0.011	0.988	0.000
T37.3 Other antiprotozoal drugs	0.011	0.988	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.011	0.988	0.000
T37.1 Antimycobacterial drugs	0.011	0.988	0.000
T37.0 Sulphonamides	0.011	0.988	0.000
T41.5 Therapeutic gases	0.011	0.988	0.000
T41.4 Anaesthetic, unspecified	0.011	0.988	0.000
T41.3 Local anaesthetics	0.011	0.988	0.000
T41.2 Other and unspecified general anaesthetics	0.011	0.988	0.000
T41.1 Intravenous anaesthetics	0.011	0.988	0.000
T41.0 Inhaled anaesthetics	0.011	0.988	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.011	0.988	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.011	0.988	0.000
T48.5 Anti-common-cold drugs	0.011	0.988	0.000
T48.4 Expectorants	0.011	0.988	0.000
T48.3 Antitussives	0.011	0.988	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.011	0.988	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.988	0.000
T48.0 Oxytocic drugs	0.011	0.988	0.000
T49.9 Topical agent, unspecified	0.011	0.988	0.000
T49.8 Other topical agents	0.011	0.988	0.000
T49.7 Dental drugs, topically applied	0.011	0.988	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.011	0.988	0.000
T49.5 Ophthalmological drugs and preparations	0.011	0.988	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.011	0.988	0.000
T49.3 Emollients, demulcents and protectants	0.011	0.988	0.000
T49.2 Local astringents and local detergents	0.011	0.988	0.000
T49.1 Antipruritics	0.011	0.988	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.011	0.988	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.011	0.988	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.011	0.988	0.000
T46.7 Peripheral vasodilators	0.011	0.988	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.011	0.988	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.011	0.988	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.011	0.988	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.011	0.988	0.000
T36.9 Systemic antibiotic, unspecified	0.011	0.989	0.000
T36.8 Other systemic antibiotics	0.011	0.989	0.000
T36.7 Antifungal antibiotics, systemically used	0.011	0.989	0.000
T36.6 Rifamycins	0.011	0.989	0.000
T36.5 Aminoglycosides	0.011	0.989	0.000
T36.4 Tetracyclines	0.011	0.989	0.000
T36.3 Macrolides	0.011	0.989	0.000
T36.2 Chloramphenicol group	0.011	0.989	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.011	0.989	0.000
T36.0 Penicillins	0.011	0.989	0.000
T42.4 Benzodiazepines	0.011	0.989	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.011	0.989	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.011	0.989	0.000
T45.8 Other primarily systemic and haematological agents	0.011	0.989	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.011	0.989	0.000
T45.6 Fibrinolysis-affecting drugs	0.011	0.989	0.000
T45.4 Iron and its compounds	0.011	0.989	0.000
T45.3 Enzymes, not elsewhere classified	0.011	0.989	0.000
T45.2 Vitamins, not elsewhere classified	0.011	0.989	0.000
T50.8 Diagnostic agents	0.011	0.989	0.000
T50.7 Analeptics and opioid receptor antagonists	0.011	0.989	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.011	0.989	0.000
T50.5 Appetite depressants	0.011	0.989	0.000
T50.4 Drugs affecting uric acid metabolism	0.011	0.989	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.011	0.989	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.011	0.989	0.000
T50.1 Loop [high-ceiling] diuretics	0.011	0.989	0.000
T50.0 Mineralocorticoids and their antagonists	0.011	0.989	0.000
T45.0 Antiallergic and antiemetic drugs	0.011	0.989	0.000
T46.1 Calcium-channel blockers	0.010	0.989	0.000
T45.5 Anticoagulants	0.010	0.990	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.010	0.990	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.010	0.990	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.007	0.993	0.000
T39.1 4-Aminophenol derivatives	0.006	0.994	0.000
T43.9 Psychotropic drug, unspecified	0.006	0.994	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
T43.6 Psychostimulants with abuse potential	0.006	0.994	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.994	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.006	0.994	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.005	0.995	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
T43.2 Other and unspecified antidepressants	0.005	0.995	0.000
A08.4 Viral intestinal infection, unspecified	0.000	0.995	0.005
I21.2 Acute transmural myocardial infarction of other sites	0.005	0.995	0.000
I21.4 Acute subendocardial myocardial infarction	0.005	0.995	0.000
I21 Acute myocardial infarction	0.004	0.996	0.000
F20.0 Paranoid schizophrenia	0.004	0.996	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.004	0.996	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.004	0.996	0.000
F20.9 Schizophrenia, unspecified	0.004	0.996	0.000
F20 Schizophrenia	0.004	0.996	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.004	0.996	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.004	0.996	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.004	0.996	0.000
K83.0 Cholangitis	0.004	0.996	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.003	0.997	0.000
F32.1 Moderate depressive episode	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
F32 Depressive episode	0.003	0.997	0.000
F20.8 Other schizophrenia	0.003	0.997	0.000
F20.6 Simple schizophrenia	0.003	0.997	0.000
F20.5 Residual schizophrenia	0.003	0.997	0.000
F20.4 Postschizophrenic depression	0.003	0.997	0.000
F20.3 Undifferentiated schizophrenia	0.003	0.997	0.000
F20.2 Catatonic schizophrenia	0.003	0.997	0.000
F20.1 Hebephrenic schizophrenia	0.003	0.997	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
A08 Viral and other specified intestinal infections	0.000	0.997	0.003
F32.0 Mild depressive episode	0.003	0.997	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.997	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.997	0.003
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
E16.2 Hypoglycaemia, unspecified	0.003	0.997	0.000
S22.40 Multiple fractures of ribs (closed)	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
W19.9 Unspecified place	0.000	0.997	0.003
F25 Schizoaffective disorders	0.003	0.997	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.997	0.003
F23 Acute and transient psychotic disorders	0.003	0.997	0.000
F32.8 Other depressive episodes	0.002	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.997	0.000
A08.5 Other specified intestinal infections	0.000	0.998	0.002
A08.3 Other viral enteritis	0.000	0.998	0.002
A08.2 Adenoviral enteritis	0.000	0.998	0.002
A08.0 Rotaviral enteritis	0.000	0.998	0.002
F22 Persistent delusional disorders	0.002	0.998	0.000
F28 Other nonorganic psychotic disorders	0.002	0.998	0.000
F24 Induced delusional disorder	0.002	0.998	0.000
F21 Schizotypal disorder	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.002	0.998	0.000
F23.8 Other acute and transient psychotic disorders	0.002	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.002	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.002	0.998	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.002	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
Z53.9 Procedure not carried out, unspecified reason	0.002	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
F06.7 Mild cognitive disorder	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.002	0.998	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.002	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.002	0.998	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M24.6 Ankylosis of joint	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
Z04.5 Examination and observation following other inflicted injury	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
S22.4 Multiple fractures of ribs	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.998	0.000
Z00.0 General medical examination	0.002	0.998	0.000
Z04.1 Examination and observation following transport accident	0.002	0.998	0.000
D41.4 Bladder	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
M24.1 Other articular cartilage disorders	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.998	0.000
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.000	0.998	0.002
F69 Unspecified disorder of adult personality and behaviour	0.002	0.998	0.000
K37 Unspecified appendicitis	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.002	0.998	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M24.9 Joint derangement, unspecified	0.002	0.998	0.000
M24.7 Protrusio acetabuli	0.002	0.998	0.000
M24.0 Loose body in joint	0.002	0.998	0.000
Z04 Examination and observation for other reasons	0.002	0.998	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.001	0.998	0.000
H49.8 Other paralytic strabismus	0.001	0.998	0.000
H49.4 Progressive external ophthalmoplegia	0.001	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.001	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
F60-F69 Disorders of adult personality and behaviour	0.002	0.998	0.000
H52.1 Myopia	0.000	0.998	0.002
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.001	0.998	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.001	0.998	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.001	0.998	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.001	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.001	0.998	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.001	0.998	0.000
M24.64 Ankylosis of joint (Hand)	0.001	0.998	0.000
M24.63 Ankylosis of joint (Forearm)	0.001	0.998	0.000
M24.62 Ankylosis of joint (Upper arm)	0.001	0.998	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.001	0.998	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.001	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
Z04.8 Examination and observation for other specified reasons	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
Z57.7 Occupational exposure to vibration	0.002	0.998	0.000
Z57.6 Occupational exposure to extreme temperature	0.002	0.998	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.002	0.998	0.000
Z57.1 Occupational exposure to radiation	0.002	0.998	0.000
Z57.0 Occupational exposure to noise	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
H40.1 Primary open-angle glaucoma	0.000	0.998	0.002
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.001	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
M24.5 Contracture of joint	0.001	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
M24.24 Disorder of ligament (Hand)	0.001	0.998	0.000
S02.6 Fracture of mandible	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.001	0.998	0.000
M24.18 Other articular cartilage disorders (Other)	0.001	0.998	0.000
M24.14 Other articular cartilage disorders (Hand)	0.001	0.998	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.001	0.998	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.001	0.998	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.998	0.002
A04.5 Campylobacter enteritis	0.000	0.998	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.998	0.000
E16.3 Increased secretion of glucagon	0.001	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
M79.60 Pain in limb (Multiple sites)	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.001	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.001	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.001	0.998	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.002	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.001	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.998	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.998	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.998	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.998	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.998	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.998	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.998	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.998	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.998	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.998	0.000
E16.1 Other hypoglycaemia	0.001	0.998	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.001	0.998	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.998	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.001	0.998	0.000
F06.5 Organic dissociative disorder	0.001	0.998	0.000
F06.4 Organic anxiety disorder	0.001	0.998	0.000
F06.3 Organic mood [affective] disorders	0.001	0.998	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.001	0.998	0.000
F06.1 Organic catatonic disorder	0.001	0.998	0.000
F06.0 Organic hallucinosis	0.001	0.998	0.000
F60.9 Personality disorder, unspecified	0.001	0.998	0.000
K56.4 Other impaction of intestine	0.002	0.998	0.000
M84.0 Malunion of fracture	0.001	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.998	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
D23.1 Skin of eyelid, including canthus	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.001	0.998	0.000
F60.8 Other specific personality disorders	0.001	0.998	0.000
F60.7 Dependent personality disorder	0.001	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.001	0.998	0.000
F60.5 Anankastic personality disorder	0.001	0.998	0.000
F60.4 Histrionic personality disorder	0.001	0.998	0.000
F60.2 Dissocial personality disorder	0.001	0.998	0.000
F60.1 Schizoid personality disorder	0.001	0.998	0.000
F60.0 Paranoid personality disorder	0.001	0.998	0.000
F30 Manic episode	0.001	0.998	0.000
M24.09 Loose body in joint (Site unspecified)	0.001	0.998	0.000
M24.08 Loose body in joint (Other)	0.001	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.001	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.001	0.998	0.000
M24.04 Loose body in joint (Hand)	0.001	0.998	0.000
M24.03 Loose body in joint (Forearm)	0.001	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.001	0.998	0.000
M24.00 Loose body in joint (Multiple sites)	0.001	0.998	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.001	0.998	0.000
M24.79 Protrusio acetabuli-Site unspec	0.001	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.001	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.001	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.001	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.001	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.001	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.001	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.001	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.001	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.001	0.998	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.001	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.001	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.001	0.998	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.001	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.001	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.001	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.001	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.001	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.001	0.998	0.000
F30.9 Manic episode, unspecified	0.001	0.998	0.000
Z04.6 General psychiatric examination, requested by authority	0.001	0.998	0.000
Z04.4 Examination and observation following alleged rape and seduction	0.001	0.998	0.000
Z04.2 Examination and observation following work accident	0.001	0.998	0.000
Z04.0 Blood-alcohol and blood-drug test	0.001	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.001	0.998	0.000
F01 Vascular dementia	0.001	0.998	0.000
F68 Other disorders of adult personality and behaviour	0.001	0.998	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.001	0.998	0.000
F65 Disorders of sexual preference	0.001	0.998	0.000
F64 Gender identity disorders	0.001	0.998	0.000
F63 Habit and impulse disorders	0.001	0.998	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.001	0.998	0.000
F61 Mixed and other personality disorders	0.001	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.001	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.001	0.998	0.000
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.001	0.998	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.001	0.999	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.001	0.999	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.001	0.999	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.001	0.999	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.001	0.999	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.001	0.999	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.001	0.999	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.001	0.999	0.000
D41.2 Ureter	0.001	0.999	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.001	0.999	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.001	0.999	0.000
M84.06 Malunion of fracture (Lower leg)	0.001	0.999	0.000
F30.2 Mania with psychotic symptoms	0.001	0.999	0.000
K91.3 Postoperative intestinal obstruction	0.001	0.999	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.001	0.999	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.001	0.999	0.000
M24.59 Contracture of joint (Site unspecified)	0.001	0.999	0.000
M24.58 Contracture of joint (Other)	0.001	0.999	0.000
M24.57 Contracture of joint (Ankle and foot)	0.001	0.999	0.000
M24.56 Contracture of joint (Lower leg)	0.001	0.999	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations