TreeWAS – Variant ID: rs10488631

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.9 Rheumatoid arthritis, unspecified	0.258	0.742	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.249	0.751	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.246	0.754	0.000
M06 Other rheumatoid arthritis	0.244	0.756	0.000
M06.0 Seronegative rheumatoid arthritis	0.232	0.768	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.771	0.229
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.227	0.773	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.227	0.773	0.000
F31 Bipolar affective disorder	0.000	0.775	0.225
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.790	0.210
M06.98 Rheumatoid arthritis, unspecified (Other)	0.206	0.794	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.203	0.797	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.203	0.797	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.798	0.202
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.200	0.800	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.804	0.196
M06.4 Inflammatory polyarthropathy	0.195	0.805	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.190	0.810	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.185	0.815	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.818	0.182
M06.3 Rheumatoid nodule	0.182	0.818	0.000
M35.0 Sicca syndrome [Sjogren]	0.181	0.819	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.824	0.176
M06.8 Other specified rheumatoid arthritis	0.175	0.825	0.000
M06.2 Rheumatoid bursitis	0.175	0.825	0.000
M06.1 Adult-onset Still's disease	0.175	0.825	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.828	0.172
M06.08 Seronegative rheumatoid arthritis (Other)	0.167	0.833	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.167	0.833	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.167	0.833	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.167	0.833	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.167	0.833	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.167	0.833	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.167	0.833	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.162	0.838	0.000
F31.8 Other bipolar affective disorders	0.000	0.839	0.161
M05-M14 Inflammatory polyarthropathies	0.158	0.842	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.158	0.842	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.843	0.157
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.155	0.845	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.850	0.149
M35 Other systemic involvement of connective tissue	0.149	0.851	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.147	0.853	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.140	0.860	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.140	0.860	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.140	0.860	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.140	0.860	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.140	0.860	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.140	0.860	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.140	0.860	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.140	0.860	0.000
G35 Multiple sclerosis	0.140	0.860	0.000
M06.34 Rheumatoid nodule (Hand)	0.139	0.861	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.133	0.867	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.130	0.869	0.000
M06.38 Rheumatoid nodule (Other)	0.130	0.869	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.130	0.869	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.130	0.869	0.000
M06.33 Rheumatoid nodule (Forearm)	0.130	0.869	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.130	0.869	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.130	0.869	0.000
M13 Other arthritis	0.129	0.871	0.000
M25.56 Pain in joint (Lower leg)	0.127	0.873	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.126	0.874	0.000
M06.18 Adult-onset Still's disease (Other)	0.126	0.874	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.126	0.874	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.126	0.874	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.126	0.874	0.000
M06.14 Adult-onset Still's disease (Hand)	0.126	0.874	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.126	0.874	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.126	0.874	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.126	0.874	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.126	0.874	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.126	0.874	0.000
M06.28 Rheumatoid bursitis (Other)	0.126	0.874	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.126	0.874	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.126	0.874	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.126	0.874	0.000
M06.24 Rheumatoid bursitis (Hand)	0.126	0.874	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.126	0.874	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.126	0.874	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.126	0.874	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.126	0.874	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.126	0.874	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.126	0.874	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.126	0.874	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.126	0.874	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.126	0.874	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.126	0.874	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.126	0.874	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.126	0.874	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.126	0.874	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.126	0.874	0.000
M05 Seropositive rheumatoid arthritis	0.126	0.874	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.125	0.874	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.125	0.875	0.000
M25 Other joint disorders, not elsewhere classified	0.119	0.881	0.000
M20-M25 Other joint disorders	0.118	0.882	0.000
M25.5 Pain in joint	0.117	0.883	0.000
M25.50 Pain in joint (Multiple sites)	0.117	0.883	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.114	0.886	0.000
M11 Other crystal arthropathies	0.114	0.886	0.000
M12 Other specific arthropathies	0.114	0.886	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.114	0.886	0.000
M08 Juvenile arthritis	0.114	0.886	0.000
M14 Arthropathies in other diseases classified elsewhere	0.113	0.887	0.000
M35.2 Behcet's disease	0.111	0.889	0.000
M35.7 Hypermobility syndrome	0.111	0.889	0.000
M35.3 Polymyalgia rheumatica	0.111	0.889	0.000
M35.1 Other overlap syndromes	0.110	0.890	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.107	0.893	0.000
M35.8 Other specified systemic involvement of connective tissue	0.107	0.893	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.107	0.893	0.000
M35.5 Multifocal fibrosclerosis	0.107	0.893	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.107	0.893	0.000
M13.9 Arthritis, unspecified	0.106	0.894	0.000
M25.3 Other instability of joint	0.105	0.895	0.000
M25.7 Osteophyte	0.105	0.895	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.103	0.897	0.000
M13.94 Arthritis, unspecified (Hand)	0.101	0.899	0.000
M00-M03 Infectious arthropathies	0.099	0.901	0.000
M13.0 Polyarthritis, unspecified	0.099	0.901	0.000
M65-M68 Disorders of synovium and tendon	0.099	0.901	0.000
M25.59 Pain in joint (Site unspecified)	0.098	0.902	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.098	0.902	0.000
M60-M63 Disorders of muscles	0.096	0.904	0.000
M25.76 Osteophyte (Lower leg)	0.096	0.904	0.000
M25.0 Haemarthrosis	0.094	0.906	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.093	0.907	0.000
M13.8 Other specified arthritis	0.093	0.907	0.000
M32 Systemic lupus erythematosus	0.093	0.907	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.092	0.908	0.000
M13.1 Monoarthritis, not elsewhere classified	0.091	0.909	0.000
M05.8 Other seropositive rheumatoid arthritis	0.090	0.909	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.090	0.909	0.000
M05.2 Rheumatoid vasculitis	0.090	0.909	0.000
M05.1 Rheumatoid lung disease	0.090	0.909	0.000
M05.0 Felty's syndrome	0.090	0.909	0.000
M25.31 Other instability of joint (Shoulder region)	0.090	0.910	0.000
M25.34 Other instability of joint (Hand)	0.090	0.910	0.000
M11.9 Crystal arthropathy, unspecified	0.089	0.910	0.000
M25.72 Osteophyte (Upper arm)	0.089	0.911	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.088	0.912	0.000
M00 Pyogenic arthritis	0.087	0.912	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.087	0.913	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.087	0.913	0.000
M25.2 Flail joint	0.086	0.914	0.000
M25.1 Fistula of joint	0.086	0.914	0.000
M07 Psoriatic and enteropathic arthropathies	0.085	0.915	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.085	0.915	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.084	0.915	0.000
M45-M49 Spondylopathies	0.084	0.916	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.083	0.917	0.000
M65 Synovitis and tenosynovitis	0.083	0.917	0.000
M24 Other specific joint derangements	0.082	0.918	0.000
M11.8 Other specified crystal arthropathies	0.082	0.918	0.000
M11.1 Familial chondrocalcinosis	0.082	0.918	0.000
M11.0 Hydroxyapatite deposition disease	0.082	0.918	0.000
M33 Dermatopolymyositis	0.082	0.918	0.000
M08.9 Juvenile arthritis, unspecified	0.082	0.918	0.000
M08.8 Other juvenile arthritis	0.082	0.918	0.000
M08.4 Pauciarticular juvenile arthritis	0.082	0.918	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.082	0.918	0.000
M08.2 Juvenile arthritis with systemic onset	0.082	0.918	0.000
M08.1 Juvenile ankylosing spondylitis	0.082	0.918	0.000
M08.0 Juvenile rheumatoid arthritis	0.082	0.918	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.082	0.918	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.082	0.918	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.082	0.918	0.000
M09.0 Juvenile arthritis in psoriasis	0.082	0.918	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.082	0.918	0.000
M12.5 Traumatic arthropathy	0.082	0.918	0.000
M12.4 Intermittent hydrarthrosis	0.082	0.918	0.000
M12.3 Palindromic rheumatism	0.082	0.918	0.000
M12.2 Villonodular synovitis (pigmented)	0.082	0.918	0.000
M12.1 Kaschin-Beck disease	0.082	0.918	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.082	0.918	0.000
M86-M90 Other osteopathies	0.081	0.919	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.081	0.919	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.081	0.919	0.000
M14.4 Arthropathy in amyloidosis	0.081	0.919	0.000
M14.3 Lipoid dermatoarthritis	0.081	0.919	0.000
M14.2 Diabetic arthropathy	0.081	0.919	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.081	0.919	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.081	0.919	0.000
M14.6 Neuropathic arthropathy	0.080	0.920	0.000
M62 Other disorders of muscle	0.079	0.920	0.000
M30 Polyarteritis nodosa and related conditions	0.079	0.921	0.000
M25.74 Osteophyte (Hand)	0.079	0.921	0.000
M00.9 Pyogenic arthritis, unspecified	0.079	0.921	0.000
M25.71 Osteophyte (Shoulder region)	0.079	0.921	0.000
M10 Gout	0.078	0.921	0.000
M45 Ankylosing spondylitis	0.078	0.922	0.000
M25.8 Other specified joint disorders	0.077	0.923	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.077	0.923	0.000
M67 Other disorders of synovium and tendon	0.077	0.923	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.077	0.923	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.077	0.923	0.000
M25.9 Joint disorder, unspecified	0.076	0.923	0.000
M25.06 Haemarthrosis (Lower leg)	0.076	0.924	0.000
M91-M94 Chondropathies	0.076	0.924	0.000
M25.36 Other instability of joint (Lower leg)	0.076	0.924	0.000
M25.39 Other instability of joint (Site unspecified)	0.076	0.924	0.000
M25.38 Other instability of joint (Other)	0.076	0.924	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.076	0.924	0.000
M25.33 Other instability of joint (Forearm)	0.076	0.924	0.000
M25.32 Other instability of joint (Upper arm)	0.076	0.924	0.000
M25.30 Other instability of joint (Multiple sites)	0.076	0.924	0.000
M60 Myositis	0.075	0.925	0.000
M25.79 Osteophyte (Site unspecified)	0.075	0.925	0.000
M25.73 Osteophyte (Forearm)	0.075	0.925	0.000
M25.70 Osteophyte (Multiple sites)	0.075	0.925	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.075	0.925	0.000
M80-M85 Disorders of bone density and structure	0.075	0.925	0.000
M34 Systemic sclerosis	0.075	0.925	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.074	0.926	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.074	0.926	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.074	0.926	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.074	0.926	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.074	0.926	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.074	0.926	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.074	0.926	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.074	0.926	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.074	0.926	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.074	0.926	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.074	0.926	0.000
M02 Reactive arthropathies	0.073	0.927	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.073	0.927	0.000
M21 Other acquired deformities of limbs	0.073	0.927	0.000
M40-M43 Deforming dorsopathies	0.072	0.927	0.000
M66 Spontaneous rupture of synovium and tendon	0.072	0.928	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.072	0.928	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.072	0.928	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.072	0.928	0.000
M11.2 Other chondrocalcinosis	0.072	0.928	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.071	0.929	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.071	0.929	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.071	0.929	0.000
M13.08 Polyarthritis, unspecified (Other)	0.071	0.929	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.071	0.929	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.071	0.929	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.071	0.929	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.071	0.929	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.071	0.929	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.071	0.929	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.071	0.929	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.071	0.929	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.070	0.929	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.070	0.929	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.070	0.929	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.070	0.929	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.070	0.929	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.070	0.930	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.070	0.930	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.069	0.931	0.000
M61 Calcification and ossification of muscle	0.069	0.931	0.000
M25.37 Other instability of joint (Ankle and foot)	0.068	0.932	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.068	0.932	0.000
M89 Other disorders of bone	0.068	0.932	0.000
M25.09 Haemarthrosis (Site unspecified)	0.068	0.932	0.000
M25.08 Haemarthrosis (Other)	0.068	0.932	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.068	0.932	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.068	0.932	0.000
M25.04 Haemarthrosis (Hand)	0.068	0.932	0.000
M25.03 Haemarthrosis (Forearm)	0.068	0.932	0.000
M25.02 Haemarthrosis (Upper arm)	0.068	0.932	0.000
M25.01 Haemarthrosis (Shoulder region)	0.068	0.932	0.000
M25.00 Haemarthrosis (Multiple sites)	0.068	0.932	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.068	0.932	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.067	0.933	0.000
M25.52 Pain in joint (Upper arm)	0.067	0.933	0.000
M67.4 Ganglion	0.067	0.933	0.000
M13.89 Other specified arthritis (Site unspecified)	0.067	0.933	0.000
M13.88 Other specified arthritis (Other)	0.067	0.933	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.067	0.933	0.000
M13.86 Other specified arthritis (Lower leg)	0.067	0.933	0.000
M13.85 Other specified arthritis (Pelvic region and thigh)	0.067	0.933	0.000
M13.84 Other specified arthritis (Hand)	0.067	0.933	0.000
M13.83 Other specified arthritis (Forearm)	0.067	0.933	0.000
M13.82 Other specified arthritis (Upper arm)	0.067	0.933	0.000
M13.81 Other specified arthritis (Shoulder region)	0.067	0.933	0.000
M13.80 Other specified arthritis (Multiple sites)	0.067	0.933	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.067	0.933	0.000
M32.8 Other forms of systemic lupus erythematosus	0.067	0.933	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.067	0.933	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.066	0.934	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.066	0.934	0.000
M24.5 Contracture of joint	0.066	0.934	0.000
M84 Disorders of continuity of bone	0.066	0.934	0.000
M24.6 Ankylosis of joint	0.066	0.934	0.000
M25.86 Other specified joint disorders (Lower leg)	0.066	0.934	0.000
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)	0.065	0.934	0.000
M13.18 Monoarthritis, not elsewhere classified (Other)	0.065	0.934	0.000
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)	0.065	0.934	0.000
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)	0.065	0.934	0.000
M13.14 Monoarthritis, not elsewhere classified (Hand)	0.065	0.934	0.000
M13.13 Monoarthritis, not elsewhere classified (Forearm)	0.065	0.934	0.000
M13.12 Monoarthritis, not elsewhere classified (Upper arm)	0.065	0.934	0.000
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)	0.065	0.934	0.000
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)	0.065	0.934	0.000
M05.09 Felty's syndrome (Site unspecified)	0.065	0.935	0.000
M05.08 Felty's syndrome (Other)	0.065	0.935	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.065	0.935	0.000
M05.06 Felty's syndrome (Lower leg)	0.065	0.935	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.065	0.935	0.000
M05.04 Felty's syndrome (Hand)	0.065	0.935	0.000
M05.03 Felty's syndrome (Forearm)	0.065	0.935	0.000
M05.02 Felty's syndrome (Upper arm)	0.065	0.935	0.000
M05.01 Felty's syndrome (Shoulder region)	0.065	0.935	0.000
M05.00 Felty's syndrome (Multiple sites)	0.065	0.935	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.065	0.935	0.000
M05.18 Rheumatoid lung disease (Other)	0.065	0.935	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.065	0.935	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.065	0.935	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.065	0.935	0.000
M05.14 Rheumatoid lung disease (Hand)	0.065	0.935	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.065	0.935	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.065	0.935	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.065	0.935	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.065	0.935	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.065	0.935	0.000
M05.28 Rheumatoid vasculitis (Other)	0.065	0.935	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.065	0.935	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.065	0.935	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.065	0.935	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.065	0.935	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.065	0.935	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.065	0.935	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.065	0.935	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.065	0.935	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.065	0.935	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.065	0.935	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.065	0.935	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.065	0.935	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.065	0.935	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.065	0.935	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.065	0.935	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.065	0.935	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.065	0.935	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.065	0.935	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.065	0.935	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.065	0.935	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.065	0.935	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.065	0.935	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.065	0.935	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.065	0.935	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.065	0.935	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.065	0.935	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.065	0.935	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.065	0.935	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.065	0.935	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.064	0.936	0.000
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.064	0.936	0.000
M11.98 Crystal arthropathy, unspecified (Other)	0.064	0.936	0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.064	0.936	0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.064	0.936	0.000
M11.94 Crystal arthropathy, unspecified (Hand)	0.064	0.936	0.000
M11.93 Crystal arthropathy, unspecified (Forearm)	0.064	0.936	0.000
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.064	0.936	0.000
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.064	0.936	0.000
M11.90 Crystal arthropathy, unspecified (Multiple sites)	0.064	0.936	0.000
M65.1 Other infective (teno)synovitis	0.064	0.936	0.000
M25.88 Other specified joint disorders (Other)	0.064	0.936	0.000
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.063	0.936	0.000
M49 Spondylopathies in diseases classified elsewhere	0.063	0.937	0.000
M25.58 Pain in joint (Other)	0.063	0.937	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.063	0.937	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.063	0.937	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.063	0.937	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.063	0.937	0.000
M21.7 Unequal limb length (acquired)	0.062	0.938	0.000
M25.54 Pain in joint (Hand)	0.062	0.938	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.062	0.938	0.000
M25.19 Fistula of joint (Site unspecified)	0.061	0.938	0.000
M25.18 Fistula of joint (Other)	0.061	0.938	0.000
M25.17 Fistula of joint (Ankle and foot)	0.061	0.938	0.000
M25.16 Fistula of joint (Lower leg)	0.061	0.938	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.061	0.938	0.000
M25.14 Fistula of joint (Hand)	0.061	0.938	0.000
M25.13 Fistula of joint (Forearm)	0.061	0.938	0.000
M25.12 Fistula of joint (Upper arm)	0.061	0.938	0.000
M25.11 Fistula of joint (Shoulder region)	0.061	0.938	0.000
M25.10 Fistula of joint (Multiple sites)	0.061	0.938	0.000
M25.29 Flail joint (Site unspecified)	0.061	0.938	0.000
M25.28 Flail joint (Other)	0.061	0.938	0.000
M25.27 Flail joint (Ankle and foot)	0.061	0.938	0.000
M25.26 Flail joint (Lower leg)	0.061	0.938	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.061	0.938	0.000
M25.24 Flail joint (Hand)	0.061	0.938	0.000
M25.23 Flail joint (Forearm)	0.061	0.938	0.000
M25.22 Flail joint (Upper arm)	0.061	0.938	0.000
M25.21 Flail joint (Shoulder region)	0.061	0.938	0.000
M25.20 Flail joint (Multiple sites)	0.061	0.938	0.000
M65.8 Other synovitis and tenosynovitis	0.061	0.939	0.000
M13.93 Arthritis, unspecified (Forearm)	0.061	0.939	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.061	0.939	0.000
M07.6 Other enteropathic arthropathies	0.061	0.939	0.000
M07.5 Arthropathy in ulcerative colitis	0.061	0.939	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.061	0.939	0.000
M07.2 Psoriatic spondylitis	0.061	0.939	0.000
M07.1 Arthritis mutilans	0.061	0.939	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.061	0.939	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.061	0.939	0.000
M99 Biomechanical lesions, not elsewhere classified	0.061	0.939	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.061	0.939	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.061	0.939	0.000
M36.3 Arthropathy in other blood disorders	0.061	0.939	0.000
M36.2 Haemophilic arthropathy	0.061	0.939	0.000
M36.1 Arthropathy in neoplastic disease	0.061	0.939	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.061	0.939	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.061	0.939	0.000
M84.0 Malunion of fracture	0.060	0.940	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.060	0.940	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.060	0.940	0.000
M60.9 Myositis, unspecified	0.060	0.940	0.000
M67.43 Ganglion, wrist	0.060	0.940	0.000
M33.1 Other dermatomyositis	0.060	0.940	0.000
M65.2 Calcific tendinitis	0.060	0.940	0.000
M65.0 Abscess of tendon sheath	0.060	0.940	0.000
M30.0 Polyarteritis nodosa	0.059	0.941	0.000
M24.9 Joint derangement, unspecified	0.059	0.941	0.000
M24.7 Protrusio acetabuli	0.059	0.941	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.059	0.941	0.000
M11.09 Hydroxyapatite deposition disease (Site unspecified)	0.059	0.941	0.000
M11.08 Hydroxyapatite deposition disease (Other)	0.059	0.941	0.000
M11.07 Hydroxyapatite deposition disease (Ankle and foot)	0.059	0.941	0.000
M11.06 Hydroxyapatite deposition disease (Lower leg)	0.059	0.941	0.000
M11.05 Hydroxyapatite deposition disease (Pelvic region and thigh)	0.059	0.941	0.000
M11.04 Hydroxyapatite deposition disease (Hand)	0.059	0.941	0.000
M11.03 Hydroxyapatite deposition disease (Forearm)	0.059	0.941	0.000
M11.02 Hydroxyapatite deposition disease (Upper arm)	0.059	0.941	0.000
M11.01 Hydroxyapatite deposition disease (Shoulder region)	0.059	0.941	0.000
M11.00 Hydroxyapatite deposition disease (Multiple sites)	0.059	0.941	0.000
M11.19 Familial chondrocalcinosis (Site unspecified)	0.059	0.941	0.000
M11.18 Familial chondrocalcinosis (Other)	0.059	0.941	0.000
M11.17 Familial chondrocalcinosis (Ankle and foot)	0.059	0.941	0.000
M11.16 Familial chondrocalcinosis (Lower leg)	0.059	0.941	0.000
M11.15 Familial chondrocalcinosis (Pelvic region and thigh)	0.059	0.941	0.000
M11.14 Familial chondrocalcinosis (Hand)	0.059	0.941	0.000
M11.13 Familial chondrocalcinosis (Forearm)	0.059	0.941	0.000
M11.12 Familial chondrocalcinosis (Upper arm)	0.059	0.941	0.000
M11.11 Familial chondrocalcinosis (Shoulder region)	0.059	0.941	0.000
M11.10 Familial chondrocalcinosis (Multiple sites)	0.059	0.941	0.000
M11.89 Other specified crystal arthropathies (Site unspecified)	0.059	0.941	0.000
M11.88 Other specified crystal arthropathies (Other)	0.059	0.941	0.000
M11.87 Other specified crystal arthropathies (Ankle and foot)	0.059	0.941	0.000
M11.86 Other specified crystal arthropathies (Lower leg)	0.059	0.941	0.000
M11.85 Other specified crystal arthropathies (Pelvic region and thigh)	0.059	0.941	0.000
M11.84 Other specified crystal arthropathies (Hand)	0.059	0.941	0.000
M11.83 Other specified crystal arthropathies (Forearm)	0.059	0.941	0.000
M11.82 Other specified crystal arthropathies (Upper arm)	0.059	0.941	0.000
M11.81 Other specified crystal arthropathies (Shoulder region)	0.059	0.941	0.000
M11.80 Other specified crystal arthropathies (Multiple sites)	0.059	0.941	0.000
M33.9 Dermatopolymyositis, unspecified	0.059	0.941	0.000
M33.0 Juvenile dermatomyositis	0.059	0.941	0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.059	0.941	0.000
M08.08 Juvenile rheumatoid arthritis (Other)	0.059	0.941	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.059	0.941	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.059	0.941	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.059	0.941	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.059	0.941	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.059	0.941	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.059	0.941	0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.059	0.941	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.059	0.941	0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)	0.059	0.941	0.000
M08.18 Juvenile ankylosing spondylitis (Other)	0.059	0.941	0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)	0.059	0.941	0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)	0.059	0.941	0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)	0.059	0.941	0.000
M08.14 Juvenile ankylosing spondylitis (Hand)	0.059	0.941	0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)	0.059	0.941	0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)	0.059	0.941	0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)	0.059	0.941	0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)	0.059	0.941	0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)	0.059	0.941	0.000
M08.28 Juvenile arthritis with systemic onset (Other)	0.059	0.941	0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)	0.059	0.941	0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)	0.059	0.941	0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)	0.059	0.941	0.000
M08.24 Juvenile arthritis with systemic onset (Hand)	0.059	0.941	0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)	0.059	0.941	0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)	0.059	0.941	0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)	0.059	0.941	0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)	0.059	0.941	0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)	0.059	0.941	0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)	0.059	0.941	0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)	0.059	0.941	0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)	0.059	0.941	0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)	0.059	0.941	0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)	0.059	0.941	0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)	0.059	0.941	0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)	0.059	0.941	0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)	0.059	0.941	0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)	0.059	0.941	0.000
M08.49 Pauciarticular juvenile arthritis (Site unspecified)	0.059	0.941	0.000
M08.48 Pauciarticular juvenile arthritis (Other)	0.059	0.941	0.000
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)	0.059	0.941	0.000
M08.46 Pauciarticular juvenile arthritis (Lower leg)	0.059	0.941	0.000
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)	0.059	0.941	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations