TreeWAS – Variant ID: rs10496992

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N93.0 Postcoital and contact bleeding	0.520	0.480	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.943	0.057
K41 Femoral hernia	0.000	0.952	0.048
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.954	0.046
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.965	0.034
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.965	0.034
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.965	0.034
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.966	0.034
N93 Other abnormal uterine and vaginal bleeding	0.032	0.967	0.000
K40-K46 Hernia	0.000	0.985	0.015
D86.0 Sarcoidosis of lung	0.015	0.985	0.000
K42 Umbilical hernia	0.000	0.986	0.014
K45 Other abdominal hernia	0.000	0.986	0.014
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.986	0.014
K22.2 Oesophageal obstruction	0.000	0.986	0.014
D86 Sarcoidosis	0.014	0.986	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.986	0.014
D86.9 Sarcoidosis, unspecified	0.013	0.987	0.000
D86.8 Sarcoidosis of other and combined sites	0.012	0.988	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.000	0.989	0.011
K86.3 Pseudocyst of pancreas	0.011	0.989	0.000
K42.1 Umbilical hernia with gangrene	0.000	0.989	0.010
K45.1 Other specified abdominal hernia with gangrene	0.000	0.989	0.010
K43 Ventral hernia	0.000	0.990	0.010
D86.1 Sarcoidosis of lymph nodes	0.010	0.990	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.990	0.010
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.990	0.010
D86.3 Sarcoidosis of skin	0.010	0.990	0.000
D80-D89 Certain disorders involving the immune mechanism	0.010	0.990	0.000
D80 Immunodeficiency with predominantly antibody defects	0.009	0.991	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.009	0.991	0.000
D84 Other immunodeficiencies	0.009	0.991	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.009	0.991	0.000
D82 Immunodeficiency associated with other major defects	0.008	0.992	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.992	0.008
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.992	0.008
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.992	0.008
K43.4 Parastomal hernia with gangrene	0.000	0.992	0.008
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.992	0.008
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.992	0.008
D84.9 Immunodeficiency, unspecified	0.008	0.992	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.008	0.992	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.008	0.992	0.000
K86 Other diseases of pancreas	0.008	0.992	0.000
D81 Combined immunodeficiencies	0.007	0.993	0.000
D83 Common variable immunodeficiency	0.007	0.993	0.000
K86.1 Other chronic pancreatitis	0.007	0.993	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.007	0.993	0.000
K43.1 Ventral hernia with gangrene	0.000	0.993	0.007
D80.8 Other immunodeficiencies with predominantly antibody defects	0.007	0.993	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.007	0.993	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.007	0.993	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.007	0.993	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.007	0.993	0.000
K46 Unspecified abdominal hernia	0.000	0.993	0.006
K86.8 Other specified diseases of pancreas	0.007	0.993	0.000
D84.8 Other specified immunodeficiencies	0.006	0.994	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.006	0.994	0.000
D84.1 Defects in the complement system	0.006	0.994	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.006	0.994	0.000
D82.1 Di George's syndrome	0.006	0.994	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.006	0.994	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.006	0.994	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.006	0.994	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.006	0.994	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.006	0.994	0.000
D82.2 Immunodeficiency with short-limbed stature	0.006	0.994	0.000
D82.0 Wiskott-Aldrich syndrome	0.006	0.994	0.000
K86.2 Cyst of pancreas	0.006	0.994	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.006	0.994	0.000
G91.9 Hydrocephalus, unspecified	0.006	0.994	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.006	0.994	0.000
D81.9 Combined immunodeficiency, unspecified	0.005	0.994	0.000
D81.8 Other combined immunodeficiencies	0.005	0.994	0.000
D81.7 Major histocompatibility complex class II deficiency	0.005	0.994	0.000
D81.6 Major histocompatibility complex class I deficiency	0.005	0.994	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.005	0.994	0.000
D81.4 Nezelof's syndrome	0.005	0.994	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.005	0.994	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.005	0.994	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.005	0.994	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.005	0.994	0.000
D83.8 Other common variable immunodeficiencies	0.005	0.994	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.005	0.994	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.005	0.994	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.005	0.994	0.000
D83.9 Common variable immunodeficiency, unspecified	0.005	0.995	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.005	0.995	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.005	0.995	0.000
G91 Hydrocephalus	0.005	0.995	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.005	0.995	0.000
N81.8 Other female genital prolapse	0.000	0.995	0.005
M54.46 Lumbago with sciatica (Lumbar region)	0.005	0.995	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.995	0.005
Z51.4 Preparatory care for treatment, not elsewhere classified	0.005	0.995	0.000
G91.0 Communicating hydrocephalus	0.005	0.995	0.000
D89.3 Immune reconstitution syndrome	0.005	0.995	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.995	0.005
G91.3 Posttraumatic hydrocephalus, unspecified	0.005	0.995	0.000
G91.2 Normal-pressure hydrocephalus	0.005	0.995	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.005	0.995	0.000
H72.0 Central perforation of tympanic membrane	0.005	0.995	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.000	0.995	0.004
K86.9 Disease of pancreas, unspecified	0.004	0.996	0.000
G91.1 Obstructive hydrocephalus	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
G91.8 Other hydrocephalus	0.004	0.996	0.000
G57.6 Lesion of plantar nerve	0.004	0.996	0.000
K44 Diaphragmatic hernia	0.000	0.996	0.004
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.004	0.996	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.004	0.996	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.003	0.996	0.000
D63.0 Anaemia in neoplastic disease	0.004	0.996	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.004	0.996	0.000
K40 Inguinal hernia	0.000	0.997	0.003
M54.4 Lumbago with sciatica	0.003	0.997	0.000
S63.6 Sprain and strain of finger(s)	0.000	0.997	0.003
K44.1 Diaphragmatic hernia with gangrene	0.000	0.997	0.003
D25.1 Intramural leiomyoma of uterus	0.003	0.997	0.000
I67.8 Other specified cerebrovascular diseases	0.003	0.997	0.000
Z63.4 Disappearance and death of family member	0.000	0.997	0.003
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.997	0.003
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.003	0.997	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.003	0.997	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.003	0.997	0.000
M54.44 Lumbago with sciatica-Thoracic	0.003	0.997	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.003	0.997	0.000
M54.42 Lumbago with sciatica-Cervical	0.003	0.997	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.003	0.997	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.003	0.997	0.000
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.997	0.003
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.997	0.003
J93.1 Other spontaneous pneumothorax	0.000	0.997	0.003
R74.8 Abnormal levels of other serum enzymes	0.003	0.997	0.000
Y77.3 Surgical instruments, materials and devices (including sutures)	0.002	0.997	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.997	0.003
F06.7 Mild cognitive disorder	0.000	0.998	0.002
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
D60-D64 Aplastic and other anaemias	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.998	0.002
W25.9 Unspecified place	0.000	0.998	0.002
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
Y73.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.998	0.002
K29.4 Chronic atrophic gastritis	0.000	0.998	0.002
W13.9 Unspecified place	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
L29.2 Pruritus vulvae	0.000	0.998	0.002
M54.49 Lumbago with sciatica (Site unspecified)	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.998	0.002
J02.9 Acute pharyngitis, unspecified	0.002	0.998	0.000
R90.0 Intracranial space-occupying lesion	0.000	0.998	0.002
D61 Other aplastic anaemias	0.002	0.998	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.002	0.998	0.000
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
Z50.5 Speech therapy	0.002	0.998	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.002	0.998	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.002	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.998	0.000
O64.1 Obstructed labour due to breech presentation	0.002	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
Y73.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Z72.2 Drug use	0.002	0.998	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.002	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.998	0.002
I15.1 Hypertension secondary to other renal disorders	0.002	0.998	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
Z54.0 Convalescence following surgery	0.002	0.998	0.000
Z82.3 Family history of stroke	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.998	0.002
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
S00.8 Superficial injury of other parts of head	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y84.0 Cardiac catheterisation	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.002	0.998	0.000
D61.3 Idiopathic aplastic anaemia	0.002	0.998	0.000
D61.2 Aplastic anaemia due to other external agents	0.002	0.998	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.002	0.998	0.000
Y77.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y77.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y77.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y77.0 Diagnostic and monitoring devices	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.001	0.998	0.001
O64.5 Obstructed labour due to compound presentation	0.002	0.998	0.000
O64.4 Obstructed labour due to shoulder presentation	0.002	0.998	0.000
O64.3 Obstructed labour due to brow presentation	0.002	0.998	0.000
O64.2 Obstructed labour due to face presentation	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
Y73.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y73.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y73.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
H72 Perforation of tympanic membrane	0.002	0.998	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.002	0.998	0.000
D61.1 Drug-induced aplastic anaemia	0.002	0.998	0.000
F12.1 Harmful use	0.002	0.998	0.000
D36.0 Lymph nodes	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
D60.8 Other acquired pure red cell aplasias	0.001	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.001	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.001	0.998	0.000
N13 Obstructive and reflux uropathy	0.000	0.998	0.002
J39.2 Other diseases of pharynx	0.000	0.998	0.002
H74.0 Tympanosclerosis	0.000	0.998	0.002
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.998	0.002
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
C92.4 Acute promyelocytic leukaemia	0.000	0.998	0.001
H33.5 Other retinal detachments	0.000	0.998	0.002
N13.4 Hydroureter	0.000	0.998	0.002
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.998	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.001	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.999	0.001
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.001	0.999	0.000
M79.67 Pain in limb (Ankle and foot)	0.000	0.999	0.001
D61.9 Aplastic anaemia, unspecified	0.001	0.999	0.000
I77.1 Stricture of artery	0.000	0.999	0.001
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.999	0.001
L29.9 Pruritus, unspecified	0.000	0.999	0.001
N13.6 Pyonephrosis	0.000	0.999	0.001
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.001	0.999	0.000
E11.1 With ketoacidosis	0.000	0.999	0.001
B99 Other and unspecified infectious diseases	0.000	0.999	0.001
C54.9 Corpus uteri, unspecified	0.001	0.999	0.000
N50.8 Other specified disorders of male genital organs	0.001	0.999	0.000
Y81.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.001	0.999	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.001	0.999	0.000
H06.2 Dysthyroid exophthalmos	0.001	0.999	0.000
Y76.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.001	0.999	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.001	0.999	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.001	0.999	0.000
C92 Myeloid leukaemia	0.000	0.999	0.001
H72.1 Attic perforation of tympanic membrane	0.001	0.999	0.000
Y82.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Y71.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Y80 Physical medicine devices associated with adverse incidents	0.001	0.999	0.000
Y78 Radiological devices associated with adverse incidents	0.001	0.999	0.000
Y75 Neurological devices associated with adverse incidents	0.001	0.999	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.001	0.999	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.001	0.999	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.001	0.999	0.000
B44.9 Aspergillosis, unspecified	0.000	0.999	0.001
Q03.0 Malformations of aqueduct of Sylvius	0.001	0.999	0.000
S32.10 Fracture of sacrum (closed)	0.001	0.999	0.000
A07.1 Giardiasis [lambliasis]	0.000	0.999	0.001
A41.1 Septicaemia due to other specified staphylococcus	0.001	0.999	0.000
G80.2 Infantile hemiplegia	0.000	0.999	0.001
H05.0 Acute inflammation of orbit	0.000	0.999	0.001
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
D33.3 Cranial nerves	0.001	0.999	0.000
Y76.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y76.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y76.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y76.0 Diagnostic and monitoring devices	0.001	0.999	0.000
M60.08 Infective myositis (Other)	0.001	0.999	0.000
C92.9 Myeloid leukaemia, unspecified	0.000	0.999	0.001
O23.5 Infections of the genital tract in pregnancy	0.000	0.999	0.001
Y71.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y71.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y71.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y71.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Y82.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y82.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y82.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y82.0 Diagnostic and monitoring devices	0.001	0.999	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.001	0.999	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.999	0.001
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.999	0.001
C92.5 Acute myelomonocytic leukaemia	0.000	0.999	0.001
C92.3 Myeloid sarcoma	0.000	0.999	0.001
C92.2 Subacute myeloid leukaemia	0.000	0.999	0.001
D58.0 Hereditary spherocytosis	0.001	0.999	0.000
W25.8 Other specified place	0.000	0.999	0.001
Y81.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y81.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y81.0 Diagnostic and monitoring devices	0.001	0.999	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.999	0.001
C92.7 Other myeloid leukaemia	0.000	0.999	0.001
I87.2 Venous insufficiency (chronic) (peripheral)	0.001	0.999	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.999	0.001
H72.8 Other perforations of tympanic membrane	0.001	0.999	0.000
N80.8 Other endometriosis	0.001	0.999	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.001	0.999	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
X12.0 Home	0.001	0.999	0.000
Y70.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y70.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y70.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Y70.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y70.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Y72.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y72.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y72.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Y72.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y72.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Y74.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y74.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y74.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Y74.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y74.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Y75.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y75.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y75.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Y75.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y75.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Y78.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y78.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y78.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Y78.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y78.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Y80.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y80.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y80.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Y80.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y80.0 Diagnostic and monitoring devices	0.001	0.999	0.000
W25 Contact with sharp glass	0.000	0.999	0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999	0.000
C71.3 Parietal lobe	0.000	0.999	0.001
I77.0 Arteriovenous fistula, acquired	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
A41.8 Other specified septicaemia	0.001	0.999	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.001	0.999	0.000
S13.1 Dislocation of cervical vertebra	0.001	0.999	0.000
G80.0 Spastic cerebral palsy	0.000	0.999	0.001
H74.4 Polyp of middle ear	0.000	0.999	0.001
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.999	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
W19.2 School, other institution and public administrative area	0.001	0.999	0.000
Y81.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
D58 Other hereditary haemolytic anaemias	0.001	0.999	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.999	0.001
D58.2 Other haemoglobinopathies	0.001	0.999	0.000
S13.4 Sprain and strain of cervical spine	0.001	0.999	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
W25.6 Industrial and construction area	0.000	0.999	0.001
W25.5 Trade and service area	0.000	0.999	0.001
W25.1 Residential institution	0.000	0.999	0.001
W25.0 Home	0.000	0.999	0.001
W25.7 Farm	0.000	0.999	0.001
W25.4 Street and highway	0.000	0.999	0.001
W25.3 Sports and athletics area	0.000	0.999	0.001
W25.2 School, other institution and public administrative area	0.000	0.999	0.001
S02.10 Fracture of base of skull (closed)	0.000	0.999	0.001
S82.81 Fractures of other parts of lower leg (open)	0.000	0.999	0.001
H74.1 Adhesive middle ear disease	0.000	0.999	0.001
I85.0 Oesophageal varices with bleeding	0.000	0.999	0.001
S41.1 Open wound of upper arm	0.000	0.999	0.001
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.999	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.999	0.000
D58.1 Hereditary elliptocytosis	0.001	0.999	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.999	0.001
F06.5 Organic dissociative disorder	0.000	0.999	0.001
F06.4 Organic anxiety disorder	0.000	0.999	0.001
F06.3 Organic mood [affective] disorders	0.000	0.999	0.001
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.999	0.001
F06.1 Organic catatonic disorder	0.000	0.999	0.001
F06.0 Organic hallucinosis	0.000	0.999	0.001
H72.2 Other marginal perforations of tympanic membrane	0.001	0.999	0.000
S50.8 Other superficial injuries of forearm	0.001	0.999	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
W29.9 Unspecified place	0.001	0.999	0.000
Z58.8 Other problems related to physical environment	0.000	0.999	0.001
Q03 Congenital hydrocephalus	0.001	0.999	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.999	0.001
M25.45 Effusion of joint (Pelvic region and thigh)	0.001	0.999	0.000
W25.09 Contact with sharp glass; Home; During unspecified activity	0.000	0.999	0.001
W25.03 Contact with sharp glass; Home; While engaged in other types of work	0.000	0.999	0.001
W25.18 Contact with sharp glass; Residential institution;While engaged in other specified activities	0.000	0.999	0.001
W25.52 Contact with sharp glass; Trade and service area;While working for income	0.000	0.999	0.001
W25.62 Contact with sharp glass; Industrial and construction area ;While working for income	0.000	0.999	0.001
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.999	0.001
Q43.9 Congenital malformation of intestine, unspecified	0.001	0.999	0.000
C16.0 Cardia	0.000	0.999	0.001
F64.0 Transsexualism	0.001	0.999	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.001	0.999	0.000
Q03.8 Other congenital hydrocephalus	0.001	0.999	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.001	0.999	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.999	0.001
T42.4 Benzodiazepines	0.001	0.999	0.000
S52.80 Fracture of other parts of forearm (closed)	0.000	0.999	0.001
H00.1 Chalazion	0.001	0.999	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.001	0.999	0.000
D55-D59 Haemolytic anaemias	0.001	0.999	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
D32.9 Meninges, unspecified	0.000	0.999	0.001
I05.0 Mitral stenosis	0.001	0.999	0.000
I72.4 Aneurysm of artery of lower extremity	0.001	0.999	0.000
I86.8 Varicose veins of other specified sites	0.001	0.999	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
Z30.2 Sterilisation	0.001	0.999	0.000
Z93.1 Gastrostomy status	0.000	0.999	0.001
D75.2 Essential thrombocytosis	0.000	0.999	0.001
J93.0 Spontaneous tension pneumothorax	0.000	0.999	0.001
L93.0 Discoid lupus erythematosus	0.001	0.999	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.001	0.999	0.000
Q04.8 Other specified congenital malformations of brain	0.001	0.999	0.000
D57 Sickle-cell disorders	0.001	0.999	0.000
D55 Anaemia due to enzyme disorders	0.001	0.999	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.001	0.999	0.000
S52.50 Fracture of lower end of radius (closed)	0.000	0.999	0.001
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.999	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.999	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.999	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.999	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.999	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.999	0.000
D57.8 Other sickle-cell disorders	0.001	0.999	0.000
D57.3 Sickle-cell trait	0.001	0.999	0.000
D57.2 Double heterozygous sickling disorders	0.001	0.999	0.000
D57.1 Sickle-cell anaemia without crisis	0.001	0.999	0.000
D57.0 Sickle-cell anaemia with crisis	0.001	0.999	0.000
O43.8 Other placental disorders	0.000	0.999	0.001
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.999	0.001
Z46.7 Fitting and adjustment of orthopaedic device	0.000	0.999	0.001
S52.51 Fracture of lower end of radius (open)	0.000	0.999	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
I15.9 Seconday hypertension, unspecified	0.001	0.999	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.000	0.999	0.001
J93.8 Other pneumothorax	0.000	0.999	0.001
J94.8 Other specified pleural conditions	0.001	0.999	0.000
L12.1 Cicatricial pemphigoid	0.001	0.999	0.000
M22.0 Recurrent dislocation of patella	0.001	0.999	0.000
S05.9 Injury of eye and orbit, part unspecified	0.001	0.999	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.999	0.000
S13.3 Multiple dislocations of neck	0.001	0.999	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.999	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.001	0.999	0.000
T91.1 Sequelae of fracture of spine	0.000	0.999	0.001
W23.4 Street and highway	0.000	0.999	0.001
Y79.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y79.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Z49.2 Other dialysis	0.000	0.999	0.001
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.999	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.999	0.001
D56 Thalassaemia	0.001	0.999	0.000
J91 Pleural effusion in conditions classified elsewhere	0.001	0.999	0.000
W13 Fall from, out of or through building or structure	0.001	0.999	0.000
M25.71 Osteophyte (Shoulder region)	0.001	0.999	0.000
M60.09 Infective myositis (Site unspecified)	0.001	0.999	0.000
M60.07 Infective myositis (Ankle and foot)	0.001	0.999	0.000
M60.06 Infective myositis (Lower leg)	0.001	0.999	0.000
M60.04 Infective myositis (Hand)	0.001	0.999	0.000
M60.03 Infective myositis (Forearm)	0.001	0.999	0.000
M60.02 Infective myositis (Upper arm)	0.001	0.999	0.000
M60.01 Infective myositis (Shoulder region)	0.001	0.999	0.000
M60.00 Infective myositis (Multiple sites)	0.001	0.999	0.000
M60.89 Other myositis (Site unspecified)	0.001	0.999	0.000
W13.08 Fall from, out of or through building or structure; Home; While engaged in other specified activities	0.001	0.999	0.000
W13.89 Fall from, out of or through building or structure; Other specified places; During unspecified activity	0.001	0.999	0.000
D56.9 Thalassaemia, unspecified	0.001	0.999	0.000
D56.8 Other thalassaemias	0.001	0.999	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.001	0.999	0.000
D56.2 Delta-beta thalassaemia	0.001	0.999	0.000
D56.1 Beta thalassaemia	0.000	0.999	0.001
D56.0 Alpha thalassaemia	0.001	0.999	0.000
G80.4 Ataxic cerebral palsy	0.000	0.999	0.001
G80.3 Dyskinetic cerebral palsy	0.000	0.999	0.001
M60.0 Infective myositis	0.001	0.999	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.001	0.999	0.000
W13.8 Other specified place	0.001	0.999	0.000
W13.0 Home	0.001	0.999	0.000
W13.7 Farm	0.001	0.999	0.000
W13.6 Industrial and construction area	0.001	0.999	0.000
W13.5 Trade and service area	0.001	0.999	0.000
W13.4 Street and highway	0.001	0.999	0.000
W13.3 Sports and athletics area	0.001	0.999	0.000
W13.2 School, other institution and public administrative area	0.001	0.999	0.000
W13.1 Residential institution	0.001	0.999	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.999	0.001
C52 Malignant neoplasm of vagina	0.001	0.999	0.000
G80 Infantile cerebral palsy	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations