TreeWAS – Variant ID: rs10501570

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.040	0.960	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.032	0.968	0.000
O16 Unspecified maternal hypertension	0.028	0.972	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.026	0.974	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.026	0.974	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.025	0.975	0.000
O15 Eclampsia	0.023	0.977	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.023	0.977	0.000
O12.0 Gestational oedema	0.022	0.978	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.021	0.979	0.000
O12.2 Gestational oedema with proteinuria	0.019	0.981	0.000
O12.1 Gestational proteinuria	0.019	0.981	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.019	0.981	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.019	0.981	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.019	0.981	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.019	0.981	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.019	0.981	0.000
O14.1 Severe preeclampsia	0.019	0.981	0.000
O15.9 Eclampsia, unspecified as to time period	0.017	0.983	0.000
O15.2 Eclampsia in the puerperium	0.017	0.983	0.000
O15.1 Eclampsia in labour	0.017	0.983	0.000
O15.0 Eclampsia in pregnancy	0.017	0.983	0.000
O14.2 HELLP syndrome	0.017	0.983	0.000
H04.1 Other disorders of lachrymal gland	0.016	0.984	0.000
O14.9 Preeclampsia, unspecified	0.016	0.984	0.000
O14.0 Moderate preeclampsia	0.015	0.985	0.000
H04 Disorders of lachrymal system	0.013	0.987	0.000
H04.8 Other disorders of lachrymal system	0.011	0.989	0.000
H04.6 Other changes in lachrymal passages	0.011	0.989	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.010	0.990	0.000
R68.8 Other specified general symptoms and signs	0.010	0.990	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.009	0.991	0.000
H04.4 Chronic inflammation of lachrymal passages	0.009	0.991	0.000
H04.0 Dacryoadenitis	0.009	0.991	0.000
H04.2 Epiphora	0.009	0.991	0.000
H61.2 Impacted cerumen	0.008	0.992	0.000
H04.9 Disorder of lachrymal system, unspecified	0.007	0.993	0.000
H33.0 Retinal detachment with retinal break	0.006	0.994	0.000
H02.9 Disorder of eyelid, unspecified	0.000	0.994	0.006
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.006	0.994	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.005	0.995	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O85-O92 Complications predominantly related to the puerperium	0.005	0.995	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
H05.0 Acute inflammation of orbit	0.005	0.995	0.000
O23 Infections of genito-urinary tract in pregnancy	0.005	0.995	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O86.4 Pyrexia of unknown origin following delivery	0.005	0.995	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
O86 Other puerperal infections	0.004	0.995	0.000
O82.0 Delivery by elective Caesarean section	0.005	0.995	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O23.5 Infections of the genital tract in pregnancy	0.005	0.995	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.004	0.996	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O97 Death from sequelae of direct obstetric causes	0.004	0.996	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.004	0.996	0.000
O95 Obstetric death of unspecified cause	0.004	0.996	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O89 Complications of anaesthesia during the puerperium	0.004	0.996	0.000
E29.1 Testicular hypofunction	0.000	0.996	0.004
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.004	0.996	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.004	0.996	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
H33 Retinal detachments and breaks	0.004	0.996	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.004	0.996	0.000
O86.1 Other infection of genital tract following delivery	0.004	0.996	0.000
T79.6 Traumatic ischaemia of muscle	0.004	0.996	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O87 Venous complications in the puerperium	0.004	0.996	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.004	0.996	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.004	0.996	0.000
T79.7 Traumatic subcutaneous emphysema	0.004	0.996	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.004	0.996	0.000
O90 Complications of the puerperium, not elsewhere classified	0.004	0.996	0.000
H05 Disorders of orbit	0.004	0.996	0.000
O21 Excessive vomiting in pregnancy	0.004	0.996	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.004	0.996	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.004	0.996	0.000
O91 Infections of breast associated with childbirth	0.004	0.996	0.000
O88 Obstetric embolism	0.004	0.996	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.004	0.996	0.000
H01 Other inflammation of eyelid	0.004	0.996	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.004	0.996	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.004	0.996	0.000
S32 Fracture of lumbar spine and pelvis	0.004	0.996	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.000	0.996	0.004
O23.3 Infections of other parts of urinary tract in pregnancy	0.004	0.996	0.000
O23.2 Infections of urethra in pregnancy	0.004	0.996	0.000
O23.1 Infections of bladder in pregnancy	0.004	0.996	0.000
O23.0 Infections of kidney in pregnancy	0.004	0.996	0.000
R68 Other general symptoms and signs	0.004	0.996	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.004	0.996	0.000
O80-O84 Delivery	0.004	0.996	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O86.8 Other specified puerperal infections	0.003	0.996	0.000
O86.3 Other genito-urinary tract infections following delivery	0.003	0.996	0.000
S32.4 Fracture of acetabulum	0.004	0.996	0.000
S32.3 Fracture of ilium	0.003	0.996	0.000
S32.40 Fracture of acetabulum (closed)	0.003	0.996	0.000
O82 Single delivery by Caesarean section	0.003	0.996	0.000
S32.30 Fracture of ilium (closed)	0.003	0.997	0.000
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
H33.5 Other retinal detachments	0.003	0.997	0.000
H33.4 Traction detachment of retina	0.003	0.997	0.000
H33.3 Retinal breaks without detachment	0.003	0.997	0.000
O29 Complications of anaesthesia during pregnancy	0.003	0.997	0.000
O25 Malnutrition in pregnancy	0.003	0.997	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.003	0.997	0.000
H01.8 Other specified inflammation of eyelid	0.003	0.997	0.000
H06.2 Dysthyroid exophthalmos	0.003	0.997	0.000
H33.1 Retinoschisis and retinal cysts	0.003	0.997	0.000
S30.2 Contusion of external genital organs	0.003	0.997	0.000
H01.0 Blepharitis	0.003	0.997	0.000
O87.2 Haemorrhoids in the puerperium	0.003	0.997	0.000
H01.1 Non-infectious dermatoses of eyelid	0.003	0.997	0.000
O96.9 Death from unspecified obstetric cause	0.003	0.997	0.000
O96.1 Death from indirect obstetric cause	0.003	0.997	0.000
O96.0 Death from direct obstetric cause	0.003	0.997	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.003	0.997	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.003	0.997	0.000
O97.0 Death from sequelae of direct obstetric cause	0.003	0.997	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.003	0.997	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.6 Failed or difficult intubation during the puerperium	0.003	0.997	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.003	0.997	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.003	0.997	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.003	0.997	0.000
O90.1 Disruption of perineal obstetric wound	0.003	0.997	0.000
O85 Puerperal sepsis	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
O90.9 Complication of the puerperium, unspecified	0.003	0.997	0.000
T79.5 Traumatic anuria	0.003	0.997	0.000
O24 Diabetes mellitus in pregnancy	0.003	0.997	0.000
O21.8 Other vomiting complicating pregnancy	0.003	0.997	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.003	0.997	0.000
T79.8 Other early complications of trauma	0.003	0.997	0.000
H05.8 Other disorders of orbit	0.003	0.997	0.000
O92.7 Other and unspecified disorders of lactation	0.003	0.997	0.000
O92.6 Galactorrhoea	0.003	0.997	0.000
O92.5 Suppressed lactation	0.003	0.997	0.000
O92.4 Hypogalactia	0.003	0.997	0.000
O92.3 Agalactia	0.003	0.997	0.000
O92.1 Cracked nipple associated with childbirth	0.003	0.997	0.000
O92.0 Retracted nipple associated with childbirth	0.003	0.997	0.000
O22 Venous complications in pregnancy	0.003	0.997	0.000
O84 Multiple delivery	0.003	0.997	0.000
O87.9 Venous complication in the puerperium, unspecified	0.003	0.997	0.000
O87.8 Other venous complications in the puerperium	0.003	0.997	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.003	0.997	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.003	0.997	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.003	0.997	0.000
C34.3 Lower lobe, bronchus or lung	0.003	0.997	0.000
T79.9 Unspecified early complication of trauma	0.003	0.997	0.000
T79.4 Traumatic shock	0.003	0.997	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.003	0.997	0.000
T79.1 Fat embolism (traumatic)	0.003	0.997	0.000
T79.0 Air embolism (traumatic)	0.003	0.997	0.000
Y84.0 Cardiac catheterisation	0.000	0.997	0.003
S30.0 Contusion of lower back and pelvis	0.003	0.997	0.000
O86.2 Urinary tract infection following delivery	0.003	0.997	0.000
O90.5 Postpartum thyroiditis	0.003	0.997	0.000
O90.4 Postpartum acute renal failure	0.003	0.997	0.000
O90.3 Cardiomyopathy in the puerperium	0.003	0.997	0.000
O90.0 Disruption of Caesarean section wound	0.003	0.997	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.003	0.997	0.000
H05.4 Enophthalmos	0.003	0.997	0.000
H05.3 Deformity of orbit	0.003	0.997	0.000
H05.1 Chronic inflammatory disorders of orbit	0.003	0.997	0.000
N72 Inflammatory disease of cervix uteri	0.000	0.997	0.003
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.003	0.997	0.000
O88.8 Other obstetric embolism	0.003	0.997	0.000
O88.3 Obstetric pyaemic and septic embolism	0.003	0.997	0.000
O88.2 Obstetric blood-clot embolism	0.003	0.997	0.000
O88.1 Amniotic fluid embolism	0.003	0.997	0.000
O88.0 Obstetric air embolism	0.003	0.997	0.000
O90.2 Haematoma of obstetric wound	0.003	0.997	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.003	0.997	0.000
O91.1 Abscess of breast associated with childbirth	0.003	0.997	0.000
O91.0 Infection of nipple associated with childbirth	0.003	0.997	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.003	0.997	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.003	0.997	0.000
K81.1 Chronic cholecystitis	0.003	0.997	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.003	0.997	0.000
O36.9 Maternal care for foetal problem, unspecified	0.003	0.997	0.000
O28 Abnormal findings on antenatal screening of mother	0.003	0.997	0.000
O21.9 Vomiting of pregnancy, unspecified	0.003	0.997	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
O21.2 Late vomiting of pregnancy	0.003	0.997	0.000
R68.2 Dry mouth, unspecified	0.003	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.003	0.997	0.000
O26.0 Excessive weight gain in pregnancy	0.003	0.997	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.003	0.997	0.000
O84.2 Multiple delivery, all by Caesarean section	0.003	0.997	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.003	0.997	0.000
H05.9 Disorder of orbit, unspecified	0.003	0.997	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.003	0.997	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.003	0.997	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.003	0.997	0.000
R68.3 Clubbing of fingers	0.003	0.997	0.000
O83 Other assisted single delivery	0.003	0.997	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
S32.41 Fracture of acetabulum (open)	0.003	0.997	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.003	0.997	0.000
S32.31 Fracture of ilium (open)	0.003	0.997	0.000
H33.2 Serous retinal detachment	0.003	0.997	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.003	0.997	0.000
O82.8 Other single delivery by Caesarean section	0.003	0.997	0.000
O82.2 Delivery by Caesarean hysterectomy	0.003	0.997	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.003	0.997	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.003	0.997	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.003	0.997	0.000
O29.6 Failed or difficult intubation during pregnancy	0.003	0.997	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.003	0.997	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.003	0.997	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.003	0.997	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.003	0.997	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.003	0.997	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.003	0.997	0.000
S32.1 Fracture of sacrum	0.003	0.997	0.000
O21.0 Mild hyperemesis gravidarum	0.003	0.997	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.002	0.997	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.003	0.997	0.000
M48.02 Spinal stenosis (Cervical region)	0.003	0.997	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.997	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.997	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.997	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.002	0.997	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.002	0.997	0.000
O26.9 Pregnancy-related condition, unspecified	0.003	0.997	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.003	0.997	0.000
O22.9 Venous complication in pregnancy, unspecified	0.002	0.997	0.000
O22.8 Other venous complications in pregnancy	0.002	0.997	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.002	0.997	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.002	0.997	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.002	0.997	0.000
O22.1 Genital varices in pregnancy	0.002	0.997	0.000
O84.9 Multiple delivery, unspecified	0.002	0.997	0.000
O84.8 Other multiple delivery	0.002	0.997	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.002	0.997	0.000
O84.0 Multiple delivery, all spontaneous	0.002	0.997	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.997	0.003
M31.6 Other giant cell arteritis	0.003	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.002	0.997	0.000
O26.2 Pregnancy care of habitual aborter	0.002	0.997	0.000
H01.9 Inflammation of eyelid, unspecified	0.002	0.997	0.000
O86.0 Infection of obstetric surgical wound	0.001	0.997	0.001
F22.0 Delusional disorder	0.002	0.998	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O26.5 Maternal hypotension syndrome	0.002	0.998	0.000
O26.4 Herpes gestationis	0.002	0.998	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.002	0.998	0.000
O26.1 Low weight gain in pregnancy	0.002	0.998	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.002	0.998	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.002	0.998	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.002	0.998	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.002	0.998	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.002	0.998	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.002	0.998	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.002	0.998	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.002	0.998	0.000
S33.5 Sprain and strain of lumbar spine	0.002	0.998	0.000
S30.1 Contusion of abdominal wall	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.002	0.998	0.000
S32.20 Fracture of coccyx (closed)	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.002	0.998	0.000
O83.9 Assisted single delivery, unspecified	0.002	0.998	0.000
O83.8 Other specified assisted single delivery	0.002	0.998	0.000
O83.4 Destructive operation for delivery	0.002	0.998	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.002	0.998	0.000
O83.2 Other manipulation-assisted delivery	0.002	0.998	0.000
O83.1 Other assisted breech delivery	0.002	0.998	0.000
O83.0 Breech extraction	0.002	0.998	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.002	0.998	0.000
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.002	0.998	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.002	0.998	0.000
S32.5 Fracture of pubis	0.002	0.998	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.002	0.998	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.002	0.998	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.002	0.998	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
R90.0 Intracranial space-occupying lesion	0.000	0.998	0.002
D68.8 Other specified coagulation defects	0.002	0.998	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.002	0.998	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
S37 Injury of urinary and pelvic organs	0.002	0.998	0.000
S32.11 Fracture of sacrum (open)	0.002	0.998	0.000
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O22.4 Haemorrhoids in pregnancy	0.002	0.998	0.000
Z89.4 Acquired absence of foot and ankle	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.002	0.998	0.000
S33.4 Traumatic rupture of symphysis pubis	0.002	0.998	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.002	0.998	0.000
S33.1 Dislocation of lumbar vertebra	0.002	0.998	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
S32.01 Fracture of lumbar vertebra (open)	0.002	0.998	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
M48.0 Spinal stenosis	0.002	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.002	0.998	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.998	0.002
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.002	0.998	0.000
M48 Other spondylopathies	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
D68 Other coagulation defects	0.002	0.998	0.000
S32.51 Fracture of pubis (open)	0.002	0.998	0.000
H05.2 Exophthalmic conditions	0.001	0.998	0.001
O81.5 Delivery by combination of forceps and vacuum extractor	0.002	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.002	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.002	0.998	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.002	0.998	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.002	0.998	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.002	0.998	0.000
S34.4 Injury of lumbosacral plexus	0.002	0.998	0.000
S34.3 Injury of cauda equina	0.002	0.998	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.002	0.998	0.000
S34.1 Other injury of lumbar spinal cord	0.002	0.998	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.002	0.998	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.5 Injury of iliac blood vessels	0.002	0.998	0.000
S35.4 Injury of renal blood vessels	0.002	0.998	0.000
S35.3 Injury of portal or splenic vein	0.002	0.998	0.000
S35.2 Injury of coeliac or mesenteric artery	0.002	0.998	0.000
S35.1 Injury of inferior vena cava	0.002	0.998	0.000
S35.0 Injury of abdominal aorta	0.002	0.998	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.2 Traumatic amputation of external genital organs	0.002	0.998	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.0 Crushing injury of external genital organs	0.002	0.998	0.000
O62.2 Other uterine inertia	0.000	0.998	0.002
S36.1 Injury of liver or gallbladder	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
O00-O08 Pregnancy with abortive outcome	0.002	0.998	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.002	0.998	0.000
S31.4 Open wound of vagina and vulva	0.002	0.998	0.000
S37.9 Injury of unspecified pelvic organ	0.002	0.998	0.000
S37.8 Injury of other pelvic organs	0.002	0.998	0.000
S37.7 Injury of multiple pelvic organs	0.002	0.998	0.000
S37.6 Injury of uterus	0.002	0.998	0.000
S37.5 Injury of Fallopian tube	0.002	0.998	0.000
S37.4 Injury of ovary	0.002	0.998	0.000
S37.3 Injury of urethra	0.002	0.998	0.000
S37.2 Injury of bladder	0.002	0.998	0.000
S37.1 Injury of ureter	0.002	0.998	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.002	0.998	0.000
O81.3 Other and unspecified forceps delivery	0.002	0.998	0.000
Y04.8 Other specified place	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
O81.0 Low forceps delivery	0.002	0.998	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.002	0.998	0.000
S36.7 Injury of multiple intra-abdominal organs	0.002	0.998	0.000
S36.6 Injury of rectum	0.002	0.998	0.000
S36.5 Injury of colon	0.002	0.998	0.000
S36.4 Injury of small intestine	0.002	0.998	0.000
S36.3 Injury of stomach	0.002	0.998	0.000
S36.2 Injury of pancreas	0.002	0.998	0.000
M48.8 Other specified spondylopathies	0.002	0.998	0.000
E29 Testicular dysfunction	0.000	0.998	0.002
K51.8 Other ulcerative colitis	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
I86.4 Gastric varices	0.000	0.998	0.002
S37.0 Injury of kidney	0.002	0.998	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.002	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
S36.8 Injury of other intra-abdominal organs	0.002	0.998	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.002	0.998	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.002	0.998	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
J86.9 Pyothorax without fistula	0.002	0.998	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.002	0.998	0.000
S31.5 Open wound of other and unspecified external genital organs	0.002	0.998	0.000
S31.3 Open wound of scrotum and testes	0.002	0.998	0.000
S31.2 Open wound of penis	0.002	0.998	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.002	0.998	0.000
T79-T79 Certain early complications of trauma	0.002	0.998	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
S36.0 Injury of spleen	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
M48.9 Spondylopathy, unspecified	0.002	0.998	0.000
M48.4 Fatigue fracture of vertebra	0.002	0.998	0.000
M48.3 Traumatic spondylopathy	0.002	0.998	0.000
M48.2 Kissing spine	0.002	0.998	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.002	0.998	0.000
R27.8 Other and unspecified lack of coordination	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
O02 Other abnormal products of conception	0.002	0.998	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.002	0.998	0.000
S31.0 Open wound of lower back and pelvis	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
O07 Failed attempted abortion	0.002	0.998	0.000
O06 Unspecified abortion	0.002	0.998	0.000
O05 Other abortion	0.002	0.998	0.000
O01 Hydatidiform mole	0.002	0.998	0.000
Z89 Acquired absence of limb	0.002	0.998	0.000
M48.04 Spinal stenosis (Thoracic region)	0.002	0.998	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.001	0.998	0.000
D68.5 Primary Thrombophilia	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.001	0.998	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.001	0.998	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.001	0.998	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.001	0.998	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.001	0.998	0.000
S37.31 Injury of urethra (with open wound into cavity)	0.001	0.998	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.001	0.998	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.001	0.998	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.001	0.998	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.001	0.998	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.001	0.998	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.001	0.998	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.001	0.998	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.001	0.998	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.001	0.998	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.001	0.998	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.001	0.998	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.001	0.998	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.001	0.998	0.000
I86.1 Scrotal varices	0.000	0.998	0.002
O82.1 Delivery by emergency Caesarean section	0.001	0.998	0.001
S36.21 Injury of pancreas (with open wound into cavity)	0.001	0.998	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.001	0.998	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.001	0.998	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.001	0.998	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.001	0.998	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.001	0.998	0.000
S36.51 Injury of colon (with open wound into cavity)	0.001	0.998	0.000
S36.50 Injury of colon (without open wound into cavity)	0.001	0.998	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.001	0.998	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.001	0.998	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.001	0.998	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.001	0.998	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.001	0.998	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.001	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.001
E29.8 Other testicular dysfunction	0.000	0.998	0.001
E29.0 Testicular hyperfunction	0.000	0.998	0.001
H53.9 Visual disturbance, unspecified	0.002	0.998	0.000
F22 Persistent delusional disorders	0.002	0.998	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.001	0.998	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.001	0.998	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.001	0.998	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.001	0.998	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.001	0.998	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.001	0.998	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.001	0.998	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.001	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.001	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.001	0.998	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.001	0.998	0.000
M31 Other necrotising vasculopathies	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations