TreeWAS – Variant ID: rs10504229

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S02.40 Fracture of malar and maxillary bones (closed)	0.013	0.987	0.000
H35.8 Other specified retinal disorders	0.000	0.990	0.010
S19.9 Unspecified injury of neck	0.010	0.990	0.000
C77.9 Lymph node, unspecified	0.009	0.991	0.000
S02.4 Fracture of malar and maxillary bones	0.009	0.991	0.000
S62.60 Fracture of other finger (closed)	0.008	0.992	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.006	0.993	0.000
S02.30 Fracture of orbital floor (closed)	0.006	0.994	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.994	0.006
Y45.1 Salicylates	0.000	0.994	0.006
S02.80 Fractures of other skull and facial bones (closed)	0.006	0.994	0.000
S02.3 Fracture of orbital floor	0.006	0.994	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.994	0.006
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.994	0.006
S02.8 Fractures of other skull and facial bones	0.006	0.994	0.000
S02 Fracture of skull and facial bones	0.006	0.994	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.994	0.006
Y45.0 Opioids and related analgesics	0.000	0.994	0.006
E05.9 Thyrotoxicosis, unspecified	0.005	0.995	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.995	0.005
S19 Other and unspecified injuries of neck	0.005	0.995	0.000
Y44.2 Anticoagulants	0.000	0.995	0.005
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.995	0.005
Y52 Agents primarily affecting the cardiovascular system	0.000	0.995	0.005
Y45.5 4-Aminophenol derivatives	0.000	0.995	0.005
S02.31 Fracture of orbital floor (open)	0.004	0.995	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.996	0.004
Y45.4 Antirheumatics	0.000	0.996	0.004
S02.9 Fracture of skull and facial bones, part unspecified	0.004	0.996	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.996	0.004
S02.81 Fractures of other skull and facial bones (open)	0.004	0.996	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.996	0.004
S02.1 Fracture of base of skull	0.004	0.996	0.000
S29.9 Unspecified injury of thorax	0.004	0.996	0.000
H25.8 Other senile cataract	0.000	0.996	0.004
S02.0 Fracture of vault of skull	0.004	0.996	0.000
S02.7 Multiple fractures involving skull and facial bones	0.004	0.996	0.000
Y54.3 Benzothiadiazine derivatives	0.000	0.996	0.004
Y44 Agents primarily affecting blood constituents	0.000	0.996	0.004
Y45.2 Propionic acid derivatives	0.000	0.996	0.004
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.996	0.004
Y45.8 Other analgesics and antipyretics	0.000	0.996	0.004
S19.7 Multiple injuries of neck	0.004	0.996	0.000
S19.8 Other specified injuries of neck	0.004	0.996	0.000
T78.4 Allergy, unspecified	0.000	0.996	0.004
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.996	0.004
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.996	0.004
Y54.5 Other diuretics	0.000	0.996	0.004
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.004	0.996	0.000
Z04.3 Examination and observation following other accident	0.000	0.996	0.004
Y54.8 Agents affecting uric acid metabolism	0.000	0.996	0.003
S02.5 Fracture of tooth	0.003	0.997	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.003	0.997	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.997	0.003
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
Y52.1 Calcium-channel blockers	0.000	0.997	0.003
D47.1 Chronic myeloproliferative disease	0.000	0.997	0.003
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.997	0.003
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.997	0.003
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
E28 Ovarian dysfunction	0.000	0.997	0.003
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.003
Y54.9 Mineral salts, not elsewhere classified	0.000	0.997	0.003
Y54.7 Agents affecting calcification	0.000	0.997	0.003
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
Y54.4 Loop [high-ceiling] diuretics	0.000	0.997	0.003
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.997	0.003
Y54.0 Mineralocorticoids	0.000	0.997	0.003
S02.11 Fracture of base of skull (open)	0.003	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.000	0.997	0.003
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.000	0.997	0.003
S02.01 Fracture of vault of skull (open)	0.003	0.997	0.000
S02.6 Fracture of mandible	0.003	0.997	0.000
S02.2 Fracture of nasal bones	0.003	0.997	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.003	0.997	0.000
Y40 Systemic antibiotics	0.000	0.997	0.003
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.997	0.003
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.997	0.003
Y44.7 Plasma substitutes	0.000	0.997	0.003
Y44.6 Natural blood and blood products	0.000	0.997	0.003
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.997	0.003
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.997	0.003
S02.10 Fracture of base of skull (closed)	0.003	0.997	0.000
Y47.1 Benzodiazepines	0.000	0.997	0.003
Y59 Other and unspecified vaccines and biological substances	0.000	0.997	0.003
Y58 Bacterial vaccines	0.000	0.997	0.003
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.997	0.003
N94.1 Dyspareunia	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.000	0.997	0.003
S02.00 Fracture of vault of skull (closed)	0.003	0.997	0.000
S62.6 Fracture of other finger	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
O75.8 Other specified complications of labour and delivery	0.003	0.997	0.000
S29 Other and unspecified injuries of thorax	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.997	0.003
T78 Adverse effects, not elsewhere classified	0.000	0.997	0.003
S02.70 Multiple fractures involving skull and facial bones (closed)	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
Y48.3 Local anaesthetics	0.000	0.997	0.003
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.997	0.003
S02.51 Fracture of tooth (open)	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
M79.62 Pain in limb (Upper arm)	0.000	0.997	0.003
D47.2 Monoclonal gammopathy	0.000	0.997	0.003
T78.3 Angioneurotic oedema	0.000	0.997	0.003
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.997	0.003
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.003
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.003
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.997	0.003
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.997	0.003
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.997	0.003
Y51.0 Anticholinesterase agents	0.000	0.997	0.003
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.997	0.003
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.997	0.003
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.997	0.003
Y47.4 Bromine compounds	0.000	0.997	0.003
Y47.3 Paraldehyde	0.000	0.997	0.003
Y47.2 Chloral derivatives	0.000	0.997	0.003
Y47.0 Barbiturates, not elsewhere classified	0.000	0.997	0.003
E28.9 Ovarian dysfunction, unspecified	0.000	0.997	0.003
E28.8 Other ovarian dysfunction	0.000	0.997	0.003
E28.1 Androgen excess	0.000	0.997	0.003
E28.0 Oestrogen excess	0.000	0.997	0.003
H54.4 Blindness, one eye	0.000	0.997	0.003
K65.9 Peritonitis, unspecified	0.000	0.997	0.003
Y44.5 Thrombolytic drugs	0.000	0.997	0.002
Y48.4 Anaesthetic, unspecified	0.000	0.997	0.003
C90.0 Multiple myeloma	0.000	0.997	0.003
M95.0 Acquired deformity of nose	0.003	0.997	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.997	0.003
Y48.5 Therapeutic gases	0.000	0.997	0.002
Y48.1 Parenteral anaesthetics	0.000	0.997	0.002
Y48.0 Inhaled anaesthetics	0.000	0.997	0.002
S02.61 Fracture of mandible (open)	0.002	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
E28.3 Primary ovarian failure	0.000	0.997	0.002
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.997	0.003
S02.21 Fracture of nasal bones (open)	0.002	0.997	0.000
Y40.3 Macrolides	0.000	0.997	0.002
Y48.2 Other and unspecified general anaesthetics	0.000	0.997	0.002
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.997	0.002
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.997	0.002
Y40.7 Antifungal antibiotics, systemically used	0.000	0.997	0.002
Y40.6 Rifamycins	0.000	0.997	0.002
Y40.5 Aminoglycosides	0.000	0.997	0.002
Y40.4 Tetracyclines	0.000	0.997	0.002
Y40.2 Chloramphenicol group	0.000	0.997	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.997	0.002
F25.0 Schizoaffective disorder, manic type	0.002	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.997	0.000
S29.8 Other specified injuries of thorax	0.002	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.000	0.997	0.002
Y50.8 Other central nervous system stimulants	0.000	0.997	0.002
Y50.2 Methylxanthines, not elsewhere classified	0.000	0.997	0.002
Y50.1 Opioid receptor antagonists	0.000	0.997	0.002
Y50.0 Analeptics	0.000	0.997	0.002
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.002
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.002
Y55.5 Anticommon cold drugs	0.000	0.997	0.002
Y55.4 Expectorants	0.000	0.997	0.002
Y55.3 Antitussives	0.000	0.997	0.002
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.002
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.002
Y55.0 Oxytocic drugs	0.000	0.997	0.002
Y58.9 Other and unspecified bacterial vaccines	0.000	0.997	0.002
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.997	0.002
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.997	0.002
Y58.5 Diphtheria vaccine	0.000	0.997	0.002
Y58.4 Tetanus vaccine	0.000	0.997	0.002
Y58.3 Plague vaccine	0.000	0.997	0.002
Y58.2 Cholera vaccine	0.000	0.997	0.002
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.997	0.002
Y58.0 BCG vaccine	0.000	0.997	0.002
Y59.9 Vaccine or biological substance, unspecified	0.000	0.997	0.002
Y59.8 Other specified vaccines and biological substances	0.000	0.997	0.002
Y59.3 Immunoglobulin	0.000	0.997	0.002
Y59.2 Protozoal vaccines	0.000	0.997	0.002
Y59.1 Rickettsial vaccines	0.000	0.997	0.002
Y59.0 Viral vaccines	0.000	0.997	0.002
M77.12 Lateral epicondylitis (Upper arm)	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.000	0.998	0.002
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
F25 Schizoaffective disorders	0.002	0.998	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.000	0.998	0.002
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
Y49.7 Psychostimulants with abuse potential	0.000	0.998	0.002
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.000	0.998	0.002
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
F32.1 Moderate depressive episode	0.002	0.998	0.000
F20 Schizophrenia	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.002	0.998	0.000
S29.0 Injury of muscle and tendon at thorax level	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.000	0.998	0.002
Y56.9 Topical agent, unspecified	0.000	0.998	0.002
Y56.8 Other topical agents	0.000	0.998	0.002
Y56.7 Dental drugs, topically applied	0.000	0.998	0.002
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
Y56.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
Y56.3 Emollients, demulcents and protectants	0.000	0.998	0.002
Y56.2 Local astringents and local detergents	0.000	0.998	0.002
Y56.1 Antipruritics	0.000	0.998	0.002
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
Y53.7 Emetics	0.000	0.998	0.002
Y53.6 Antidiarrhoeal drugs	0.000	0.998	0.002
Y53.5 Digestants	0.000	0.998	0.002
Y53.4 Other laxatives	0.000	0.998	0.002
Y53.3 Saline and osmotic laxatives	0.000	0.998	0.002
Y53.2 Stimulant laxatives	0.000	0.998	0.002
Y53.0 Histamine H2-receptor antagonists	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.998	0.002
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
R40.2 Coma, unspecified	0.000	0.998	0.002
T78.8 Other adverse effects, not elsewhere classified	0.000	0.998	0.002
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
I97.1 Other functional disturbances following cardiac surgery	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.000	0.998	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.998	0.002
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
Y41.0 Sulphonamides	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.998	0.002
S20.2 Contusion of thorax	0.000	0.998	0.002
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.002	0.998	0.000
W06.0 Home	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
Y41.5 Antiviral drugs	0.000	0.998	0.002
Y41.4 Anthelminthics	0.000	0.998	0.002
Y41.3 Other antiprotozoal drugs	0.000	0.998	0.002
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
Y41.1 Antimycobacterial drugs	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.000	0.998	0.002
Y46.7 Anti-Parkinsonism drugs	0.000	0.998	0.002
Y46.5 Valproic acid	0.000	0.998	0.002
Y46.3 Deoxybarbiturates	0.000	0.998	0.002
Y46.1 Oxazolidinediones	0.000	0.998	0.002
Y46.0 Succinimides	0.000	0.998	0.002
D09.0 Bladder	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
K61.0 Anal abscess	0.002	0.998	0.000
R40.0 Somnolence	0.000	0.998	0.002
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
M21.1 Varus deformity, not elsewhere classified	0.000	0.998	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
M79.69 Pain in limb (Site unspecified)	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.000	0.998	0.002
D61.9 Aplastic anaemia, unspecified	0.000	0.998	0.002
E27.2 Addisonian crisis	0.000	0.998	0.002
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.000	0.998	0.002
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
E20 Hypoparathyroidism	0.000	0.998	0.002
E27.1 Primary adrenocortical insufficiency	0.000	0.998	0.002
M21.0 Valgus deformity, not elsewhere classified	0.000	0.998	0.002
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.998	0.002
E20-E35 Disorders of other endocrine glands	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.000	0.998	0.002
F20.8 Other schizophrenia	0.002	0.998	0.000
F20.6 Simple schizophrenia	0.002	0.998	0.000
F20.4 Postschizophrenic depression	0.002	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.002	0.998	0.000
F20.2 Catatonic schizophrenia	0.002	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.002	0.998	0.000
M19.0 Primary arthrosis of other joints	0.002	0.998	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.000	0.998	0.002
D23.5 Skin of trunk	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
F28 Other nonorganic psychotic disorders	0.002	0.998	0.000
F24 Induced delusional disorder	0.002	0.998	0.000
F21 Schizotypal disorder	0.002	0.998	0.000
S21 Open wound of thorax	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
S21.2 Open wound of back wall of thorax	0.002	0.998	0.000
S21.1 Open wound of front wall of thorax	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
F32.8 Other depressive episodes	0.002	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
F22 Persistent delusional disorders	0.002	0.998	0.000
F31 Bipolar affective disorder	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
S21.9 Open wound of thorax, part unspecified	0.002	0.998	0.000
M79.63 Pain in limb (Forearm)	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.000	0.998	0.002
C02.1 Border of tongue	0.000	0.998	0.002
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.000	0.998	0.002
S10-S19 Injuries to the neck	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.998	0.001
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
F23 Acute and transient psychotic disorders	0.002	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.002
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
W02.9 Unspecified place	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.002	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.998	0.002
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.998	0.002
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.002
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
K65 Peritonitis	0.000	0.998	0.002
R40 Somnolence, stupor and coma	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.001	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.001
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.002
E27.0 Other adrenocortical overactivity	0.000	0.998	0.002
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.998	0.002
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.998	0.002
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.002
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
M79.6 Pain in limb	0.000	0.998	0.002
N64.9 Disorder of breast, unspecified	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E32 Diseases of thymus	0.000	0.998	0.002
E31 Polyglandular dysfunction	0.000	0.998	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.002
E25 Adrenogenital disorders	0.000	0.998	0.002
M19.08 Primary arthrosis of other joints (Other)	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.002	0.998	0.000
M95.2 Other acquired deformity of head	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.002	0.998	0.000
S21.8 Open wound of other parts of thorax	0.001	0.998	0.000
S21.7 Multiple open wounds of thoracic wall	0.001	0.998	0.000
S21.0 Open wound of breast	0.001	0.998	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.002	0.998	0.000
M79.64 Pain in limb (Hand)	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H49.4 Progressive external ophthalmoplegia	0.002	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.001	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.001	0.998	0.000
M95.5 Acquired deformity of pelvis	0.001	0.998	0.000
M95.3 Acquired deformity of neck	0.001	0.998	0.000
M95.1 Cauliflower ear	0.001	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.001	0.998	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.998	0.000
F22.8 Other persistent delusional disorders	0.001	0.998	0.000
F30.8 Other manic episodes	0.001	0.998	0.000
F30.1 Mania without psychotic symptoms	0.001	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.001	0.998	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.002	0.998	0.000
T68 Hypothermia	0.000	0.998	0.002
C02.9 Tongue, unspecified	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.001
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.001
I30.9 Acute pericarditis, unspecified	0.000	0.998	0.002
M77.1 Lateral epicondylitis	0.002	0.998	0.000
N05.9 Unspecified	0.000	0.998	0.002
F32 Depressive episode	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.001
T66-T78 Other and unspecified effects of external causes	0.000	0.998	0.002
E24 Cushing's syndrome	0.000	0.998	0.001
M19.09 Primary arthrosis of other joints (Site unspecified)	0.002	0.998	0.000
M79.67 Pain in limb (Ankle and foot)	0.000	0.998	0.002
F23.8 Other acute and transient psychotic disorders	0.001	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.998	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.998	0.000
F32.0 Mild depressive episode	0.002	0.998	0.000
N80.8 Other endometriosis	0.002	0.998	0.000
S11.8 Open wound of other parts of neck	0.001	0.998	0.000
Y57.8 Other drugs and medicaments	0.000	0.998	0.001
Y57.7 Vitamins, not elsewhere classified	0.000	0.998	0.001
Y57.4 Pharmaceutical excipients	0.000	0.998	0.001
Y57.3 Alcohol deterrents	0.000	0.998	0.001
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.001
Y57.1 Lipotropic drugs	0.000	0.998	0.001
Y57.0 Appetite depressants [anorectics]	0.000	0.998	0.001
S17 Crushing injury of neck	0.001	0.998	0.000
S15 Injury of blood vessels at neck level	0.001	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.001	0.998	0.000
S18 Traumatic amputation at neck level	0.001	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.001	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.001	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
R40.1 Stupor	0.000	0.998	0.001
S22.2 Fracture of sternum	0.001	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.001
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.001	0.998	0.000
M79.60 Pain in limb (Multiple sites)	0.000	0.998	0.001
S62.30 Fracture of other metacarpal bone (closed)	0.001	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.001
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.001
I97.9 Postprocedural disorder of circulatory system, unspecified	0.001	0.998	0.000
I97.0 Postcardiotomy syndrome	0.001	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.001	0.998	0.000
E26 Hyperaldosteronism	0.000	0.998	0.001
M19.00 Primary arthrosis of other joints (Multiple sites)	0.001	0.998	0.000
M40.26 Other and unspecified kyphosis (Lumbar region)	0.001	0.998	0.000
S62.31 Fracture of other metacarpal bone (open)	0.001	0.998	0.000
C48.2 Peritoneum, unspecified	0.000	0.998	0.001
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.001
E25.8 Other adrenogenital disorders	0.000	0.998	0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.001
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.001
E30.8 Other disorders of puberty	0.000	0.998	0.001
E30.1 Precocious puberty	0.000	0.998	0.001
E30.0 Delayed puberty	0.000	0.998	0.001
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.001
E31.8 Other polyglandular dysfunction	0.000	0.998	0.001
E31.1 Polyglandular hyperfunction	0.000	0.998	0.001
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.001
E32.9 Disease of thymus, unspecified	0.000	0.998	0.001
E32.8 Other diseases of thymus	0.000	0.998	0.001
E32.1 Abscess of thymus	0.000	0.998	0.001
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.001
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.001
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.001
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.001
S14.1 Other and unspecified injuries of cervical spinal cord	0.001	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.001
T66 Unspecified effects of radiation	0.000	0.998	0.001
E23.6 Other disorders of pituitary gland	0.000	0.999	0.001
J32.4 Chronic pansinusitis	0.001	0.999	0.000
N05.2 Diffuse membranous glomerulonephritis	0.000	0.999	0.001
Y42.5 Other oestrogens and progestogens	0.000	0.999	0.001
H54 Blindness and low vision	0.000	0.999	0.001
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.001	0.999	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.999	0.001
K12.1 Other forms of stomatitis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations