TreeWAS – Variant ID: rs10504543

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S62.61 Fracture of other finger (open)	0.000	0.967	0.033
R60.0 Localised oedema	0.029	0.971	0.000
S62.6 Fracture of other finger	0.000	0.980	0.020
R60 Oedema, not elsewhere classified	0.016	0.984	0.000
S62.60 Fracture of other finger (closed)	0.000	0.984	0.016
R60.9 Oedema, unspecified	0.015	0.985	0.000
E83.4 Disorders of magnesium metabolism	0.012	0.988	0.000
E83.5 Disorders of calcium metabolism	0.011	0.989	0.000
E83 Disorders of mineral metabolism	0.010	0.990	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.010	0.990	0.000
E83.3 Disorders of phosphorus metabolism	0.009	0.991	0.000
R60.1 Generalised oedema	0.009	0.991	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.008	0.992	0.000
S62 Fracture at wrist and hand level	0.000	0.992	0.008
E83.8 Other disorders of mineral metabolism	0.007	0.992	0.000
E83.2 Disorders of zinc metabolism	0.007	0.992	0.000
E83.0 Disorders of copper metabolism	0.007	0.992	0.000
S62.5 Fracture of thumb	0.000	0.993	0.007
S62.50 Fracture of thumb (closed)	0.000	0.993	0.007
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.994	0.006
D69.6 Thrombocytopenia, unspecified	0.000	0.994	0.006
S62.3 Fracture of other metacarpal bone	0.000	0.994	0.006
M67.1 Other contracture of tendon (sheath)	0.006	0.994	0.000
S62.1 Fracture of other carpal bone(s)	0.000	0.994	0.005
S62.4 Multiple fractures of metacarpal bones	0.000	0.995	0.005
S62.51 Fracture of thumb (open)	0.000	0.995	0.005
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.995	0.005
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.005	0.995	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.005	0.995	0.000
R87.6 Abnormal cytological findings	0.000	0.995	0.005
S62.31 Fracture of other metacarpal bone (open)	0.000	0.995	0.005
M05.9 Seropositive rheumatoid arthritis, unspecified	0.005	0.995	0.000
M67 Other disorders of synovium and tendon	0.005	0.995	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.995	0.005
M67.8 Other specified disorders of synovium and tendon	0.005	0.995	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.005	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.005	0.995	0.000
S62.7 Multiple fractures of fingers	0.000	0.995	0.004
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.995	0.005
M67.0 Short Achilles tendon (acquired)	0.004	0.995	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.004	0.996	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.996	0.004
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.004	0.996	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.996	0.004
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.996	0.004
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.996	0.004
W22.9 Unspecified place	0.004	0.996	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.996	0.004
N20.2 Calculus of kidney with calculus of ureter	0.004	0.996	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.004	0.996	0.000
R87 Abnormal findings in specimens from female genital organs	0.000	0.996	0.004
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.996	0.004
M67.4 Ganglion	0.004	0.996	0.000
R52.9 Pain, unspecified	0.004	0.996	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.004	0.996	0.000
M67.3 Transient synovitis	0.004	0.996	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.996	0.004
R87.7 Abnormal histological findings	0.000	0.996	0.004
M20.4 Other hammer toe(s) (acquired)	0.004	0.996	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
T90.4 Sequelae of injury of eye and orbit	0.000	0.996	0.004
M67.2 Synovial hypertrophy, not elsewhere classified	0.004	0.996	0.000
M22.2 Patellofemoral disorders	0.000	0.996	0.004
R87.9 Unspecified abnormal finding	0.000	0.996	0.003
R76.8 Other specified abnormal immunological findings in serum	0.000	0.996	0.004
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.997	0.003
S62.21 Fracture of first metacarpal bone (open)	0.000	0.997	0.003
S93.1 Dislocation of toe(s)	0.003	0.997	0.000
S62.71 Multiple fractures of fingers (open)	0.000	0.997	0.003
K83.0 Cholangitis	0.003	0.997	0.000
N28.1 Cyst of kidney, acquired	0.003	0.997	0.000
T90 Sequelae of injuries of head	0.000	0.997	0.003
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.997	0.003
I95.1 Orthostatic hypotension	0.000	0.997	0.003
H47.1 Papilloedema, unspecified	0.000	0.997	0.003
M23.5 Chronic instability of knee	0.003	0.997	0.000
R87.8 Other abnormal findings	0.000	0.997	0.003
R87.5 Abnormal microbiological findings	0.000	0.997	0.003
R87.4 Abnormal immunological findings	0.000	0.997	0.003
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.997	0.003
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.997	0.003
R87.1 Abnormal level of hormones	0.000	0.997	0.003
R87.0 Abnormal level of enzymes	0.000	0.997	0.003
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
M67.43 Ganglion, wrist	0.003	0.997	0.000
M67.49 Ganglion, multiple sites	0.003	0.997	0.000
M67.45 Ganglion, hip	0.003	0.997	0.000
M67.47 Ganglion, ankle and foot	0.003	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.997	0.003
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.003	0.997	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
E11.5 With peripheral circulatory complications	0.000	0.997	0.003
E83.1 Disorders of iron metabolism	0.003	0.997	0.000
T90.8 Sequelae of other specified injuries of head	0.000	0.997	0.003
H35.4 Peripheral retinal degeneration	0.003	0.997	0.000
S62.70 Multiple fractures of fingers (closed)	0.000	0.997	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.003	0.997	0.000
K58 Irritable bowel syndrome	0.003	0.997	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.997	0.003
W22.5 Trade and service area	0.003	0.997	0.000
C32.1 Supraglottis	0.000	0.997	0.003
M21.6 Other acquired deformities of ankle and foot	0.003	0.997	0.000
J30.1 Allergic rhinitis due to pollen	0.003	0.997	0.000
M05 Seropositive rheumatoid arthritis	0.003	0.997	0.000
T90.3 Sequelae of injury of cranial nerves	0.000	0.997	0.002
Z93.4 Other artificial openings of gastro-intestinal tract status	0.000	0.997	0.003
W22 Striking against or struck by other objects	0.003	0.997	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.002	0.997	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.002	0.997	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.002	0.997	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.997	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.002	0.997	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
S69.9 Unspecified injury of wrist and hand	0.000	0.998	0.002
T90.5 Sequelae of intracranial injury	0.000	0.998	0.002
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.000	0.998	0.002
R76.0 Raised antibody titer	0.000	0.998	0.002
R76 Other abnormal immunological findings in serum	0.000	0.998	0.002
W22.2 School, other institution and public administrative area	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
I84.4 External haemorrhoids with other complications	0.002	0.998	0.000
M05.1 Rheumatoid lung disease	0.002	0.998	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
M05.8 Other seropositive rheumatoid arthritis	0.002	0.998	0.000
M05.2 Rheumatoid vasculitis	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
S69 Other and unspecified injuries of wrist and hand	0.000	0.998	0.002
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.002	0.998	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.002	0.998	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.002	0.998	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.002	0.998	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.002	0.998	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.002	0.998	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.002	0.998	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.002	0.998	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.002	0.998	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.998	0.000
M05.0 Felty's syndrome	0.002	0.998	0.000
S69.8 Other specified injuries of wrist and hand	0.000	0.998	0.002
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.998	0.002
W22.8 Other specified place	0.002	0.998	0.000
W22.6 Industrial and construction area	0.002	0.998	0.000
W22.4 Street and highway	0.002	0.998	0.000
W22.0 Home	0.002	0.998	0.000
W22.7 Farm	0.002	0.998	0.000
W22.1 Residential institution	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
T90.0 Sequelae of superficial injury of head	0.000	0.998	0.002
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.998	0.002
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.998	0.002
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.998	0.002
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.998	0.001
R76.2 False-positive serological test for syphilis	0.000	0.998	0.002
R76.1 Abnormal reaction to tuberculin test	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
Z46.8 Fitting and adjustment of other specified devices	0.002	0.998	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.002	0.998	0.000
C50.1 Central portion of breast	0.000	0.998	0.002
M05.18 Rheumatoid lung disease (Other)	0.002	0.998	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.002	0.998	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.002	0.998	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.002	0.998	0.000
M05.14 Rheumatoid lung disease (Hand)	0.002	0.998	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.002	0.998	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.002	0.998	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.002	0.998	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.002	0.998	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.002	0.998	0.000
T50.8 Diagnostic agents	0.000	0.998	0.002
S60-S69 Injuries to the wrist and hand	0.000	0.998	0.002
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.002	0.998	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.998	0.000
M05.28 Rheumatoid vasculitis (Other)	0.002	0.998	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.002	0.998	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.002	0.998	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.002	0.998	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.002	0.998	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.002	0.998	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.002	0.998	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.002	0.998	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.998	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.998	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
S67 Crushing injury of wrist and hand	0.000	0.998	0.002
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
M05.09 Felty's syndrome (Site unspecified)	0.002	0.998	0.000
M05.08 Felty's syndrome (Other)	0.002	0.998	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.002	0.998	0.000
M05.06 Felty's syndrome (Lower leg)	0.002	0.998	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.002	0.998	0.000
M05.04 Felty's syndrome (Hand)	0.002	0.998	0.000
M05.03 Felty's syndrome (Forearm)	0.002	0.998	0.000
M05.02 Felty's syndrome (Upper arm)	0.002	0.998	0.000
M05.01 Felty's syndrome (Shoulder region)	0.002	0.998	0.000
M05.00 Felty's syndrome (Multiple sites)	0.002	0.998	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.002	0.998	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.002	0.998	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.002	0.998	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.002	0.998	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.002	0.998	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.002	0.998	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.002	0.998	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.002	0.998	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.002	0.998	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.002	0.998	0.000
W22.09 Striking against or struck by other objects; Home; During unspecified activity	0.002	0.998	0.000
W22.03 Striking against or struck by other objects; Home; While engaged in other types of work	0.002	0.998	0.000
W22.41 Striking against or struck by other objects; Street and highway;While engaged in leisure activity	0.002	0.998	0.000
W22.62 Striking against or struck by other objects; Industrial and construction area ;While working for income	0.002	0.998	0.000
W22.88 Striking against or struck by other objects; Other specified places ;While engaged in other specified activities	0.002	0.998	0.000
W22.3 Sports and athletics area	0.002	0.998	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.002	0.998	0.000
N28.8 Other specified disorders of kidney and ureter	0.002	0.998	0.000
S65 Injury of blood vessels at wrist and hand level	0.000	0.998	0.002
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.002	0.998	0.000
S65.1 Injury of radial artery at wrist and hand level	0.000	0.998	0.002
M79.70 Fibromyalgia (Multiple sites)	0.002	0.998	0.000
L57.5 Actinic granuloma	0.002	0.998	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.002	0.998	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.998	0.002
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.998	0.002
C44.1 Skin of eyelid, including canthus	0.000	0.998	0.002
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.998	0.002
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.998	0.002
M94.26 Chondromalacia (Lower leg)	0.002	0.998	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.002	0.998	0.000
M54.89 Other dorsalgia (Site unspecified)	0.002	0.998	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.002	0.998	0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.002	0.998	0.000
L92.0 Granuloma annulare	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.002
M71.38 Other bursal cyst (Other)	0.002	0.998	0.000
Z46 Fitting and adjustment of other devices	0.002	0.998	0.000
K29.1 Other acute gastritis	0.000	0.998	0.002
L57.3 Poikiloderma of Civatte	0.001	0.998	0.000
L57.2 Cutis rhomboidalis nuchae	0.001	0.998	0.000
L57.1 Actinic reticuloid	0.001	0.998	0.000
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.000	0.998	0.002
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.998	0.001
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.998	0.001
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.998	0.001
S65.5 Injury of blood vessel(s) of other finger	0.000	0.998	0.001
S65.4 Injury of blood vessel(s) of thumb	0.000	0.998	0.001
S65.3 Injury of deep palmar arch	0.000	0.998	0.001
S65.2 Injury of superficial palmar arch	0.000	0.998	0.001
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.998	0.002
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.998	0.001
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.002
D69.5 Secondary thrombocytopenia	0.000	0.998	0.001
J38.4 Oedema of larynx	0.000	0.998	0.002
Q66.3 Other congenital varus deformities of feet	0.000	0.998	0.001
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.998	0.001
D68.0 Von Willebrand's disease	0.000	0.998	0.001
D69.2 Other nonthrombocytopenic purpura	0.000	0.998	0.001
R82.9 Other and unspecified abnormal finding in urine	0.001	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.001	0.999	0.000
Q66.9 Congenital deformity of feet, unspecified	0.000	0.999	0.001
S69.7 Multiple injuries of wrist and hand	0.000	0.999	0.001
S90.3 Contusion of other and unspecified parts of foot	0.000	0.999	0.001
D68.4 Acquired coagulation factor deficiency	0.000	0.999	0.001
D69.1 Qualitative platelet defects	0.000	0.999	0.001
K55.9 Vascular disorder of intestine, unspecified	0.000	0.999	0.001
S63.6 Sprain and strain of finger(s)	0.000	0.999	0.001
Q67.5 Congenital deformity of spine	0.000	0.999	0.001
D69.8 Other specified haemorrhagic conditions	0.000	0.999	0.001
N13.4 Hydroureter	0.001	0.999	0.000
Z46.9 Fitting and adjustment of other unspecified device	0.001	0.999	0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.001	0.999	0.000
S02.50 Fracture of tooth (closed)	0.001	0.999	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.999	0.001
Q66.7 Pes cavus	0.000	0.999	0.001
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.999	0.001
Z46.3 Fitting and adjustment of dental prosthetic device	0.001	0.999	0.000
S63.1 Dislocation finger	0.000	0.999	0.001
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.999	0.001
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.999	0.001
S90.2 Contusion of toe(s) with damage to nail	0.000	0.999	0.001
X68.9 Unspecified place	0.001	0.999	0.000
Z46.4 Fitting and adjustment of orthodontic device	0.001	0.999	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.999	0.001
Q66 Congenital deformities of feet	0.000	0.999	0.001
D68.1 Hereditary factor XI deficiency	0.000	0.999	0.001
H57.1 Ocular pain	0.001	0.999	0.000
L57.4 Cutis laxa senilis	0.001	0.999	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.999	0.001
S64.8 Injury of other nerves at wrist and hand level	0.000	0.999	0.001
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.999	0.001
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.999	0.001
Q66.2 Metatarsus varus	0.000	0.999	0.001
T91.1 Sequelae of fracture of spine	0.000	0.999	0.001
D68 Other coagulation defects	0.000	0.999	0.001
T91 Sequelae of injuries of neck and trunk	0.000	0.999	0.001
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
D69.4 Other primary thrombocytopenia	0.000	0.999	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.999	0.000
G62.8 Other specified polyneuropathies	0.000	0.999	0.001
H44.0 Purulent endophthalmitis	0.001	0.999	0.000
S63.2 Multiple dislocations of fingers	0.000	0.999	0.001
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.999	0.001
S64.3 Injury of digital nerve of thumb	0.000	0.999	0.001
M54.56 Low back pain (Lumbar region)	0.001	0.999	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.999	0.001
T91.3 Sequelae of injury of spinal cord	0.000	0.999	0.001
T92 Sequelae of injuries of upper limb	0.000	0.999	0.001
W94.8 Other specified place	0.000	0.999	0.001
Z46.1 Fitting and adjustment of hearing aid	0.001	0.999	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.999	0.001
H18.8 Other specified disorders of cornea	0.000	0.999	0.001
K58.0 Irritable bowel syndrome with diarrhoea	0.001	0.999	0.000
Q66.6 Other congenital valgus deformities of feet	0.000	0.999	0.001
R30.9 Painful micturition, unspecified	0.000	0.999	0.001
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.999	0.001
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.999	0.001
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.999	0.001
D13.2 Duodenum	0.000	0.999	0.001
E04.0 Non-toxic diffuse goitre	0.000	0.999	0.001
Q66.5 Congenital pes planus	0.000	0.999	0.001
Q66.4 Talipes calcaneovalgus	0.000	0.999	0.001
Q66.1 Talipes calcaneovarus	0.000	0.999	0.001
S90.8 Other superficial injuries of ankle and foot	0.000	0.999	0.001
W06.0 Home	0.000	0.999	0.001
C50.0 Nipple and areola	0.000	0.999	0.001
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.999	0.001
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.999	0.001
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.999	0.001
D66 Hereditary factor VIII deficiency	0.000	0.999	0.001
D69.9 Haemorrhagic condition, unspecified	0.000	0.999	0.001
H49.2 Sixth [abducent] nerve palsy	0.001	0.999	0.000
M22.3 Other derangements of patella	0.000	0.999	0.001
Q61.9 Cystic kidney disease, unspecified	0.001	0.999	0.000
A69.2 Lyme disease	0.000	0.999	0.001
D69.0 Allergic purpura	0.000	0.999	0.001
D68.8 Other specified coagulation defects	0.000	0.999	0.001
G95.9 Disease of spinal cord, unspecified	0.001	0.999	0.000
R23.8 Other and unspecified skin changes	0.001	0.999	0.000
M22 Disorders of patella	0.000	0.999	0.001
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.000	0.999	0.001
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.001	0.999	0.000
D68.6 Other Thrombophilia	0.000	0.999	0.001
L98.0 Pyogenic granuloma	0.000	0.999	0.001
S64.1 Injury of median nerve at wrist and hand level	0.000	0.999	0.001
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.999	0.001
S90.0 Contusion of ankle	0.000	0.999	0.001
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.000	0.999	0.001
S61 Open wound of wrist and hand	0.000	0.999	0.001
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.000	0.999	0.001
R30.0 Dysuria	0.000	0.999	0.001
S63.5 Sprain and strain of wrist	0.000	0.999	0.001
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.999	0.001
B25.9 Cytomegaloviral disease, unspecified	0.001	0.999	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.999	0.001
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.999	0.001
M22.0 Recurrent dislocation of patella	0.000	0.999	0.001
Q67.6 Pectus excavatum	0.000	0.999	0.001
T17.8 Foreign body in other and multiple parts of respiratory tract	0.001	0.999	0.000
X67.9 Unspecified place	0.000	0.999	0.001
J94.8 Other specified pleural conditions	0.000	0.999	0.001
L95.9 Vasculitis limited to skin, unspecified	0.000	0.999	0.001
M22.1 Recurrent subluxation of patella	0.000	0.999	0.001
Q67.8 Other congenital deformities of chest	0.000	0.999	0.001
Q67.7 Pectus carinatum	0.000	0.999	0.001
Q67.3 Plagiocephaly	0.000	0.999	0.001
Q67.2 Dolichocephaly	0.000	0.999	0.001
Q67.1 Compression facies	0.000	0.999	0.001
Q67.0 Facial asymmetry	0.000	0.999	0.001
R06.6 Hiccough	0.000	0.999	0.001
V78.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.001	0.999	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.000	0.999	0.001
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.000	0.999	0.001
M79.79 Fibromyalgia (Site unspecified)	0.001	0.999	0.000
A69.9 Spirochaetal infection, unspecified	0.000	0.999	0.001
H44.2 Degenerative myopia	0.000	0.999	0.001
I80.8 Phlebitis and thrombophlebitis of other sites	0.001	0.999	0.000
N27.0 Small kidney, unilateral	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.000	0.999	0.001
R23.3 Spontaneous ecchymoses	0.001	0.999	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.999	0.001
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.999	0.001
D67 Hereditary factor IX deficiency	0.000	0.999	0.001
H57 Other disorders of eye and adnexa	0.001	0.999	0.000
I05.0 Mitral stenosis	0.001	0.999	0.000
L60.9 Nail disorder, unspecified	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.000	0.999	0.001
S63.0 Dislocation of wrist	0.000	0.999	0.001
T92.1 Sequelae of fracture of arm	0.000	0.999	0.001
N08 Glomerular disorders in diseases classified elsewhere	0.000	0.999	0.001
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.999	0.001
D37.0 Lip, oral cavity and pharynx	0.000	0.999	0.001
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
I37.1 Pulmonary valve insufficiency	0.000	0.999	0.001
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.001	0.999	0.000
J67.7 Air-conditioner and humidifier lung	0.001	0.999	0.000
J67.6 Maple-bark-stripper's lung	0.001	0.999	0.000
J67.5 Mushroom-worker's lung	0.001	0.999	0.000
J67.4 Maltworker's lung	0.001	0.999	0.000
J67.3 Suberosis	0.001	0.999	0.000
J67.1 Bagassosis	0.001	0.999	0.000
J67.0 Farmer's lung	0.001	0.999	0.000
M22.4 Chondromalacia patellae	0.000	0.999	0.001
M94.2 Chondromalacia	0.001	0.999	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.001	0.999	0.000
M22.9 Disorder of patella, unspecified	0.000	0.999	0.001
N08.8 Glomerular disorders in other diseases classified elsewhere	0.000	0.999	0.001
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.000	0.999	0.001
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.000	0.999	0.001
N08.1 Glomerular disorders in neoplastic diseases	0.000	0.999	0.001
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
Q87.4 Marfan's syndrome	0.001	0.999	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.999	0.001
M94.29 Chondromalacia (Site unspecified)	0.001	0.999	0.000
M94.28 Chondromalacia (Other)	0.001	0.999	0.000
M94.27 Chondromalacia (Ankle and foot)	0.001	0.999	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.001	0.999	0.000
M94.24 Chondromalacia (Hand)	0.001	0.999	0.000
M94.23 Chondromalacia (Forearm)	0.001	0.999	0.000
M94.22 Chondromalacia (Upper arm)	0.001	0.999	0.000
M94.21 Chondromalacia (Shoulder region)	0.001	0.999	0.000
M94.20 Chondromalacia (Multiple sites)	0.001	0.999	0.000
E11.2 With renal complications	0.000	0.999	0.001
H49.9 Paralytic strabismus, unspecified	0.001	0.999	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.000	0.999	0.001
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.000	0.999	0.001
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.999	0.001
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.999	0.001
T56.8 Other metals	0.001	0.999	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.999	0.000
D68.5 Primary Thrombophilia	0.000	0.999	0.001
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.999	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.001	0.999	0.000
N60.3 Fibrosclerosis of breast	0.000	0.999	0.001
Q61.2 Polycystic kidney, adult type	0.001	0.999	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.000	0.999	0.001
Q76.0 Spina bifida occulta	0.000	0.999	0.001
Y81.2 Prosthetic and other implants, materials and accessory devices	0.000	0.999	0.001
M72.14 Knuckle pads (Hand)	0.000	0.999	0.001
H18.1 Bullous keratopathy	0.000	0.999	0.001
H57.0 Anomalies of pupillary function	0.001	0.999	0.000
M79.7 Fibromyalgia	0.001	0.999	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.001	0.999	0.000
O73.0 Retained placenta, without haemorrhage	0.000	0.999	0.001
Q61.3 Polycystic kidney, unspecified	0.001	0.999	0.000
T19.2 Foreign body in vulva and vagina	0.001	0.999	0.000
T25.3 Burn of third degree of ankle and foot	0.001	0.999	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.001	0.999	0.000
Q68 Other congenital musculoskeletal deformities	0.000	0.999	0.001
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.000	0.999	0.001
M79.78 Fibromyalgia (Other)	0.001	0.999	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.001	0.999	0.000
M79.76 Fibromyalgia (Lower leg)	0.001	0.999	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.001	0.999	0.000
M79.74 Fibromyalgia (Hand)	0.001	0.999	0.000
M79.73 Fibromyalgia (Forearm)	0.001	0.999	0.000
M79.72 Fibromyalgia (Upper arm)	0.001	0.999	0.000
M79.71 Fibromyalgia (Shoulder region)	0.001	0.999	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.000	0.999	0.001
Q68.4 Congenital bowing of tibia and fibula	0.000	0.999	0.001
Q68.3 Congenital bowing of femur	0.000	0.999	0.001
Q68.2 Congenital deformity of knee	0.000	0.999	0.001
Q68.1 Congenital deformity of hand	0.000	0.999	0.001
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.000	0.999	0.001
Q78.0 Osteogenesis imperfecta	0.000	0.999	0.001
R74.8 Abnormal levels of other serum enzymes	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations