TreeWAS – Variant ID: rs10505725

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D68.8 Other specified coagulation defects	0.086	0.914	0.000
D68.9 Coagulation defect, unspecified	0.084	0.916	0.000
D68 Other coagulation defects	0.080	0.920	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.068	0.932	0.000
D68.2 Hereditary deficiency of other clotting factors	0.062	0.938	0.000
D68.6 Other Thrombophilia	0.061	0.939	0.000
D68.4 Acquired coagulation factor deficiency	0.058	0.942	0.000
D68.0 Von Willebrand's disease	0.046	0.954	0.000
D68.1 Hereditary factor XI deficiency	0.045	0.954	0.000
D68.5 Primary Thrombophilia	0.028	0.971	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.021	0.979	0.000
D67 Hereditary factor IX deficiency	0.016	0.984	0.000
H02.0 Entropion and trichiasis of eyelid	0.015	0.985	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.015	0.985	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.015	0.985	0.000
Z36 Antenatal screening	0.014	0.986	0.000
S22.40 Multiple fractures of ribs (closed)	0.014	0.986	0.000
D66 Hereditary factor VIII deficiency	0.014	0.986	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.013	0.986	0.000
S22.4 Multiple fractures of ribs	0.013	0.987	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.013	0.987	0.000
Z36.8 Other antenatal screening	0.012	0.988	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.012	0.988	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.012	0.988	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.012	0.988	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.012	0.988	0.000
S22.1 Multiple fractures of thoracic spine	0.011	0.988	0.000
Z39.1 Care and examination of lactating mother	0.011	0.989	0.000
Z36.5 Antenatal screening for isoimmunisation	0.011	0.989	0.000
S22.5 Flail chest	0.010	0.990	0.000
Z39 Postpartum care and examination	0.010	0.990	0.000
S22.3 Fracture of rib	0.010	0.990	0.000
S22.41 Multiple fractures of ribs (open)	0.009	0.991	0.000
Z57.2 Occupational exposure to dust	0.000	0.991	0.009
S22.50 Flail chest (closed)	0.009	0.991	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.009	0.991	0.000
S22.0 Fracture of thoracic vertebra	0.009	0.991	0.000
Z34.8 Supervision of other normal pregnancy	0.009	0.991	0.000
Z34 Supervision of normal pregnancy	0.009	0.991	0.000
O36.8 Maternal care for other specified foetal problems	0.009	0.991	0.000
S22.9 Fracture of bony thorax, part unspecified	0.008	0.991	0.000
S22.8 Fracture of other parts of bony thorax	0.008	0.991	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.008	0.991	0.000
D69 Purpura and other haemorrhagic conditions	0.008	0.992	0.000
S22.30 Fracture of rib (closed)	0.008	0.992	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.008	0.992	0.000
H26.4 After-cataract	0.000	0.992	0.008
Y42.7 Androgens and anabolic congeners	0.000	0.992	0.008
Z38 Liveborn infants according to place of birth	0.008	0.992	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.008	0.992	0.000
Z34.0 Supervision of normal first pregnancy	0.008	0.992	0.000
Z39.2 Routine postpartum follow-up	0.008	0.992	0.000
D69.5 Secondary thrombocytopenia	0.007	0.992	0.000
Z31 Procreative management	0.007	0.992	0.000
S22.51 Flail chest (open)	0.007	0.992	0.000
Z76 Persons encountering health services in other circumstances	0.007	0.993	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.993	0.007
S22.31 Fracture of rib (open)	0.007	0.993	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.993	0.007
S22.00 Fracture of thoracic vertebra (closed)	0.007	0.993	0.000
Z38.0 Singleton, born in hospital	0.007	0.993	0.000
Z76.3 Healthy person accompanying sick person	0.007	0.993	0.000
J92.0 Pleural plaque with presence of asbestos	0.007	0.993	0.000
S22.01 Fracture of thoracic vertebra (open)	0.007	0.993	0.000
M88.9 Paget's disease of bone, unspecified	0.007	0.993	0.000
Z31.4 Procreative investigation and testing	0.006	0.993	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.006	0.994	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.006	0.994	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.006	0.994	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.006	0.994	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.006	0.994	0.000
S22.2 Fracture of sternum	0.006	0.994	0.000
Z57 Occupational exposure to risk-factors	0.000	0.994	0.006
D69.9 Haemorrhagic condition, unspecified	0.006	0.994	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.994	0.006
D69.8 Other specified haemorrhagic conditions	0.006	0.994	0.000
D69.1 Qualitative platelet defects	0.006	0.994	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.994	0.006
D69.2 Other nonthrombocytopenic purpura	0.006	0.994	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.994	0.006
Z39.0 Care and examination immediately after delivery	0.006	0.994	0.000
O36 Maternal care for other known or suspected foetal problems	0.006	0.994	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.994	0.006
Y42.1 Thyroid hormones and substitutes	0.000	0.994	0.006
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.006	0.994	0.000
Z38.8 Other multiple, unspecified as to place of birth	0.006	0.994	0.000
Z38.7 Other multiple, born outside hospital	0.006	0.994	0.000
Z38.6 Other multiple, born in hospital	0.006	0.994	0.000
Z38.5 Twin, unspecified as to place of birth	0.006	0.994	0.000
Z38.4 Twin, born outside hospital	0.006	0.994	0.000
Z38.3 Twin, born in hospital	0.006	0.994	0.000
Z38.2 Singleton, unspecified as to place of birth	0.006	0.994	0.000
Z38.1 Singleton, born outside hospital	0.006	0.994	0.000
Z31.2 In vitro fertilisation	0.006	0.994	0.000
Z31.8 Other procreative management	0.006	0.994	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.994	0.006
Z31.9 Procreative management, unspecified	0.006	0.994	0.000
Z31.6 General counselling and advice on procreation	0.006	0.994	0.000
Z31.5 Genetic counselling	0.006	0.994	0.000
Z31.3 Other assisted fertilisation methods	0.006	0.994	0.000
Z31.1 Artifical insemination	0.006	0.994	0.000
Z35 Supervision of high-risk pregnancy	0.006	0.994	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
Z76.5 Malingerer [conscious situation]	0.005	0.994	0.000
Z76.4 Other boarder in health-care facility	0.005	0.994	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.005	0.994	0.000
Z76.1 Health supervision and care of foundling	0.005	0.994	0.000
Z76.0 Issue of repeat prescription	0.005	0.994	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.005	0.995	0.000
O36.5 Maternal care for poor foetal growth	0.005	0.995	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.995	0.005
J93.1 Other spontaneous pneumothorax	0.005	0.995	0.000
D69.4 Other primary thrombocytopenia	0.005	0.995	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.005	0.995	0.000
J92 Pleural plaque	0.005	0.995	0.000
Y83.4 Other reconstructive surgery	0.000	0.995	0.005
Z33 Pregnant state, incidental	0.005	0.995	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.005	0.995	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.995	0.005
M88.98 Paget's disease of bone, unspecified (Other)	0.005	0.995	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.005	0.995	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.005	0.995	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.005	0.995	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.005	0.995	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.005	0.995	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.005	0.995	0.000
Z32 Pregnancy examination and test	0.005	0.995	0.000
S22.21 Fracture of sternum (open)	0.005	0.995	0.000
Y42.2 Antithyroid drugs	0.000	0.995	0.005
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.995	0.005
Z57.7 Occupational exposure to vibration	0.000	0.995	0.005
Z57.6 Occupational exposure to extreme temperature	0.000	0.995	0.005
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.995	0.005
Z57.1 Occupational exposure to radiation	0.000	0.995	0.005
Z57.0 Occupational exposure to noise	0.000	0.995	0.005
H20.9 Iridocyclitis, unspecified	0.005	0.995	0.000
Z35.8 Supervision of other high-risk pregnancies	0.005	0.995	0.000
J92.9 Pleural plaque without asbestos	0.005	0.995	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.005	0.995	0.000
O36.2 Maternal care for hydrops foetalis	0.005	0.995	0.000
O36.6 Maternal care for excessive foetal growth	0.005	0.995	0.000
O36.1 Maternal care for other isoimmunisation	0.005	0.995	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.005	0.995	0.000
O36.4 Maternal care for intra-uterine death	0.004	0.995	0.000
Y42.4 Oral contraceptives	0.000	0.995	0.004
J93.8 Other pneumothorax	0.005	0.995	0.000
Z37 Outcome of delivery	0.004	0.996	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
O36.9 Maternal care for foetal problem, unspecified	0.004	0.996	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.004	0.996	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.004	0.996	0.000
Z35.6 Supervision of very young primigravida	0.004	0.996	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.004	0.996	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.004	0.996	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.004	0.996	0.000
X51.9 Unspecified place	0.004	0.996	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.004	0.996	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.004	0.996	0.000
D69.0 Allergic purpura	0.004	0.996	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.004	0.996	0.000
J93 Pneumothorax	0.004	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
Z32.9 Pregnancy confirmed (erroneous code. See Z321)	0.004	0.996	0.000
Z37.3 Twins, one liveborn and one stillborn	0.004	0.996	0.000
Q61.2 Polycystic kidney, adult type	0.004	0.996	0.000
Z37.1 Single stillbirth	0.004	0.996	0.000
S20-S29 Injuries to the thorax	0.004	0.996	0.000
M88 Paget's disease of bone [osteitis deformans]	0.004	0.996	0.000
I45.6 Preexcitation syndrome	0.000	0.996	0.004
G93.3 Postviral fatigue syndrome	0.000	0.996	0.004
Z35.0 Supervision of pregnancy with history of infertility	0.003	0.996	0.000
Z37.5 Other multiple births, all liveborn	0.003	0.996	0.000
Z36.9 Antenatal screening, unspecified	0.003	0.996	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
Z37.9 Outcome of delivery unspecified	0.003	0.997	0.000
Z37.7 Other multiple births, all stillborn	0.003	0.997	0.000
Z37.6 Other multiple births, some liveborn	0.003	0.997	0.000
Z37.4 Twins, both stillborn	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.003	0.997	0.000
Z35.5 Supervision of elderly primigravida	0.003	0.997	0.000
S27.2 Traumatic heamopneumothorax	0.003	0.997	0.000
Z57.3 Occupational exposure to other air contaminants	0.000	0.997	0.003
D56.3 Thalassaemia trait	0.003	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
M88.8 Paget's disease of other bones	0.003	0.997	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.003	0.997	0.000
D56 Thalassaemia	0.003	0.997	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.003	0.997	0.000
D55-D59 Haemolytic anaemias	0.003	0.997	0.000
S36.0 Injury of spleen	0.003	0.997	0.000
S20.2 Contusion of thorax	0.003	0.997	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.003	0.997	0.000
S26 Injury of heart	0.003	0.997	0.000
S25 Injury of blood vessels of thorax	0.003	0.997	0.000
L28.1 Prurigo nodularis	0.003	0.997	0.000
L28.0 Lichen simplex chronicus	0.003	0.997	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.003	0.997	0.000
M88.0 Paget's disease of skull	0.003	0.997	0.000
S20 Superficial injury of thorax	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.003	0.997	0.000
E10.4 With neurological complications	0.000	0.997	0.003
H65.9 Nonsuppurative otitis media, unspecified	0.003	0.997	0.000
J93.0 Spontaneous tension pneumothorax	0.003	0.997	0.000
D56.1 Beta thalassaemia	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
S27.1 Traumatic haemothorax	0.003	0.997	0.000
S24 Injury of nerves and spinal cord at thorax level	0.003	0.997	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.997	0.003
F40.2 Specific (isolated) phobias	0.003	0.997	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
D86.9 Sarcoidosis, unspecified	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
G93.8 Other specified disorders of brain	0.000	0.997	0.003
Z32.1 Pregnancy confirmed	0.002	0.997	0.000
S22.20 Fracture of sternum (closed)	0.002	0.997	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.002	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
S27.9 Injury of unspecified intrathoracic organ	0.002	0.997	0.000
S27.7 Multiple injuries of intrathoracic organs	0.002	0.997	0.000
S27.6 Injury of pleura	0.002	0.997	0.000
S27.5 Injury of thoracic trachea	0.002	0.997	0.000
S27.4 Injury of bronchus	0.002	0.997	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.003	0.997	0.000
D57 Sickle-cell disorders	0.002	0.997	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.002	0.997	0.000
M88.88 Paget's disease of other bones (Other)	0.002	0.997	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.002	0.997	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.002	0.997	0.000
M88.84 Paget's disease of other bones (Hand)	0.002	0.997	0.000
M88.83 Paget's disease of other bones (Forearm)	0.002	0.997	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.002	0.997	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.002	0.997	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.002	0.997	0.000
D56.9 Thalassaemia, unspecified	0.002	0.997	0.000
D56.8 Other thalassaemias	0.002	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.997	0.000
D56.2 Delta-beta thalassaemia	0.002	0.997	0.000
D56.0 Alpha thalassaemia	0.002	0.997	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.997	0.003
J94.2 Haemothorax	0.002	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
I69 Sequelae of cerebrovascular disease	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.997	0.000
Q61.8 Other cystic kidney diseases	0.002	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.997	0.000
D81 Combined immunodeficiencies	0.002	0.997	0.000
S29 Other and unspecified injuries of thorax	0.002	0.997	0.000
S21 Open wound of thorax	0.002	0.997	0.000
J90-J94 Other diseases of pleura	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
G93.6 Cerebral oedema	0.000	0.998	0.002
S20.0 Contusion of breast	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.002	0.998	0.000
L28 Lichen simplex chronicus and prurigo	0.002	0.998	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.002	0.998	0.000
S25.8 Injury of other blood vessels of thorax	0.002	0.998	0.000
S25.7 Injury of multiple blood vessels of thorax	0.002	0.998	0.000
S25.5 Injury of intercostal blood vessels	0.002	0.998	0.000
S25.4 Injury of pulmonary blood vessels	0.002	0.998	0.000
S25.3 Injury of innominate or subclavian vein	0.002	0.998	0.000
S25.2 Injury of superior vena cava	0.002	0.998	0.000
S25.1 Injury of innominate or subclavian artery	0.002	0.998	0.000
S25.0 Injury of thoracic aorta	0.002	0.998	0.000
S26.9 Injury of heart, unspecified	0.002	0.998	0.000
S26.8 Other injuries of heart	0.002	0.998	0.000
S26.0 Injury of heart with haemopericardium	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.002	0.998	0.000
S28.1 Traumatic amputation of part of thorax	0.002	0.998	0.000
S28.0 Crushed chest	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.002	0.998	0.000
S23.3 Sprain and strain of thoracic spine	0.002	0.998	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.002	0.998	0.000
S23.1 Dislocation of thoracic vertebra	0.002	0.998	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.002	0.998	0.000
M88.09 Paget's disease of skull-Site unspec	0.002	0.998	0.000
M88.08 Paget's disease of skull-Other	0.002	0.998	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.002	0.998	0.000
M88.06 Paget's disease of skull-Lower Leg	0.002	0.998	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.002	0.998	0.000
M88.04 Paget's disease of skull-Hand	0.002	0.998	0.000
M88.03 Paget's disease of skull-Forearm	0.002	0.998	0.000
M88.02 Paget's disease of skull-Upper arm	0.002	0.998	0.000
M88.01 Paget's disease of skull-Shldr region	0.002	0.998	0.000
M88.00 Paget's disease of skull-Mult sites	0.002	0.998	0.000
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
S20.7 Multiple superficial injuries of thorax	0.002	0.998	0.000
X51 Travel and motion	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
S27.3 Other injuries of lung	0.002	0.998	0.000
G93 Other disorders of brain	0.000	0.998	0.002
O32 Maternal care for known or suspected malpresentation of foetus	0.002	0.998	0.000
J94 Other pleural conditions	0.002	0.998	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.998	0.002
C90.0 Multiple myeloma	0.000	0.998	0.002
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
S23.4 Sprain and strain of ribs and sternum	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
G00.1 Pneumococcal meningitis	0.000	0.998	0.002
N97.1 Female infertility of tubal origin	0.002	0.998	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
S24.6 Injury of unspecified nerve of thorax	0.002	0.998	0.000
S24.5 Injury of other nerves of thorax	0.002	0.998	0.000
S24.4 Injury of thoracic sympathetic nerves	0.002	0.998	0.000
S24.3 Injury of peripheral nerves of thorax	0.002	0.998	0.000
S24.2 Injury of nerve root of thoracic spine	0.002	0.998	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.002	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.002	0.998	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
O32.1 Maternal care for breech presentation	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
H52.0 Hypermetropia	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
K22.8 Other specified diseases of oesophagus	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
Z37.2 Twins, both liveborn	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
O32.4 Maternal care for high head at term	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.998	0.000
S21.2 Open wound of back wall of thorax	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.000	0.998	0.002
H20 Iridocyclitis	0.002	0.998	0.000
S20.4 Other superficial injuries of back wall of thorax	0.002	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
M24.6 Ankylosis of joint	0.002	0.998	0.000
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.002	0.998	0.000
O32.0 Maternal care for unstable lie	0.002	0.998	0.000
S21.8 Open wound of other parts of thorax	0.002	0.998	0.000
S21.7 Multiple open wounds of thoracic wall	0.002	0.998	0.000
S21.0 Open wound of breast	0.002	0.998	0.000
S29.8 Other specified injuries of thorax	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.002	0.998	0.000
S29.0 Injury of muscle and tendon at thorax level	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M24.64 Ankylosis of joint (Hand)	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.002
G93.0 Cerebral cysts	0.000	0.998	0.002
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.998	0.002
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.998	0.002
L28.2 Other prurigo	0.002	0.998	0.000
R57.2 Septic shock	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.002	0.998	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.002	0.998	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.002	0.998	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.002	0.998	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.002	0.998	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
O32.6 Maternal care for compound presentation	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.002	0.998	0.000
X51.7 Farm	0.002	0.998	0.000
X51.6 Industrial and construction area	0.002	0.998	0.000
X51.5 Trade and service area	0.002	0.998	0.000
X51.4 Street and highway	0.002	0.998	0.000
X51.3 Sports and athletics area	0.002	0.998	0.000
X51.2 School, other institution and public administrative area	0.002	0.998	0.000
X51.1 Residential institution	0.002	0.998	0.000
X51.0 Home	0.002	0.998	0.000
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.998	0.002
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.002	0.998	0.000
G93.7 Reye's syndrome	0.000	0.998	0.002
J94.9 Pleural condition, unspecified	0.002	0.998	0.000
J94.0 Chylous effusion	0.002	0.998	0.000
S20.3 Other superficial injuries of front wall of thorax	0.002	0.998	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.998	0.002
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
G00.9 Bacterial meningitis, unspecified	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.998	0.002
G04.1 Tropical spastic paraplegia	0.000	0.998	0.002
G04.0 Acute disseminated encephalitis	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
S20.1 Other and unspecified superficial injuries of breast	0.002	0.998	0.000
S36.8 Injury of other intra-abdominal organs	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
N34.2 Other urethritis	0.002	0.998	0.000
S21.9 Open wound of thorax, part unspecified	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations