TreeWAS – Variant ID: rs10518765

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S52.10 Fracture of upper end of radius (closed)	0.076	0.924	0.000
R55 Syncope and collapse	0.000	0.949	0.051
S52.1 Fracture of upper end of radius	0.040	0.960	0.000
S52.11 Fracture of upper end of radius (open)	0.029	0.971	0.000
S52 Fracture of forearm	0.014	0.986	0.000
S52.6 Fracture of lower end of both ulna and radius	0.012	0.988	0.000
S52.0 Fracture of upper end of ulna	0.012	0.988	0.000
S52.2 Fracture of shaft of ulna	0.011	0.989	0.000
H52.1 Myopia	0.000	0.989	0.011
S52.60 Fracture of lower end of both ulna and radius (closed)	0.011	0.989	0.000
S52.9 Fracture of forearm, part unspecified	0.010	0.990	0.000
S52.7 Multiple fractures of forearm	0.010	0.990	0.000
S91 Open wound of ankle and foot	0.010	0.990	0.000
S90-S99 Injuries to the ankle and foot	0.010	0.990	0.000
S52.3 Fracture of shaft of radius	0.009	0.990	0.000
S52.01 Fracture of upper end of ulna (open)	0.010	0.990	0.000
S91.1 Open wound of toe(s) without damage to nail	0.010	0.990	0.000
S52.20 Fracture of shaft of ulna (closed)	0.009	0.991	0.000
S92 Fracture of foot, except ankle	0.009	0.991	0.000
S52.4 Fracture of shafts of both ulna and radius	0.009	0.991	0.000
S52.8 Fracture of other parts of forearm	0.009	0.991	0.000
S52.00 Fracture of upper end of ulna (closed)	0.009	0.991	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.009	0.991	0.000
S52.21 Fracture of shaft of ulna (open)	0.008	0.992	0.000
S92.5 Fracture of other toe	0.008	0.992	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.008	0.992	0.000
S92.1 Fracture of talus	0.008	0.992	0.000
S92.4 Fracture of great toe	0.008	0.992	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.008	0.992	0.000
S91.2 Open wound of toe(s) with damage to nail	0.008	0.992	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.008	0.992	0.000
R04.0 Epistaxis	0.000	0.992	0.008
S92.41 Fracture of great toe (open)	0.008	0.992	0.000
S90 Superficial injury of ankle and foot	0.008	0.992	0.000
S91.0 Open wound of ankle	0.008	0.992	0.000
S92.10 Fracture of talus (closed)	0.008	0.992	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.008	0.992	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.008	0.992	0.000
S52.71 Multiple fractures of forearm (open)	0.008	0.992	0.000
S52.70 Multiple fractures of forearm (closed)	0.008	0.992	0.000
S92.50 Fracture of other toe (closed)	0.008	0.992	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.007	0.992	0.000
S91.3 Open wound of other parts of foot	0.007	0.992	0.000
S52.5 Fracture of lower end of radius	0.007	0.992	0.000
S91.7 Multiple open wounds of ankle and foot	0.007	0.993	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.007	0.993	0.000
S99 Other and unspecified injuries of ankle and foot	0.007	0.993	0.000
S98 Traumatic amputation of ankle and foot	0.007	0.993	0.000
S97 Crushing injury of ankle and foot	0.007	0.993	0.000
S95 Injury of blood vessels at ankle and foot level	0.007	0.993	0.000
S94 Injury of nerves at ankle and foot level	0.007	0.993	0.000
S92.2 Fracture of other tarsal bone(s)	0.007	0.993	0.000
S52.31 Fracture of shaft of radius (open)	0.007	0.993	0.000
S93.1 Dislocation of toe(s)	0.007	0.993	0.000
K56.7 Ileus, unspecified	0.007	0.993	0.000
S92.9 Fracture of foot, unspecified	0.007	0.993	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.007	0.993	0.000
S92.7 Multiple fractures of foot	0.007	0.993	0.000
H93.1 Tinnitus	0.000	0.993	0.007
S52.81 Fracture of other parts of forearm (open)	0.006	0.993	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.006	0.993	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.006	0.993	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.006	0.993	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.006	0.993	0.000
S92.51 Fracture of other toe (open)	0.006	0.993	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.006	0.994	0.000
S52.30 Fracture of shaft of radius (closed)	0.006	0.994	0.000
S93.4 Sprain and strain of ankle	0.006	0.994	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.006	0.994	0.000
S93.5 Sprain and strain of toe(s)	0.006	0.994	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.006	0.994	0.000
S92.11 Fracture of talus (open)	0.006	0.994	0.000
S92.0 Fracture of calcaneus	0.006	0.994	0.000
S99.9 Unspecified injury of ankle and foot	0.006	0.994	0.000
S52.51 Fracture of lower end of radius (open)	0.006	0.994	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.006	0.994	0.000
S90.3 Contusion of other and unspecified parts of foot	0.006	0.994	0.000
S90.2 Contusion of toe(s) with damage to nail	0.006	0.994	0.000
S90.1 Contusion of toe(s) without damage to nail	0.006	0.994	0.000
S92.40 Fracture of great toe (closed)	0.006	0.994	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.006	0.994	0.000
S90.8 Other superficial injuries of ankle and foot	0.006	0.994	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.006	0.994	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.005	0.994	0.000
S99.7 Multiple injuries of ankle and foot	0.005	0.994	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.005	0.995	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.005	0.995	0.000
S94.8 Injury of other nerves at ankle and foot level	0.005	0.995	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.005	0.995	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.005	0.995	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.005	0.995	0.000
S94.1 Injury of medial plantar nerve	0.005	0.995	0.000
S94.0 Injury of lateral plantar nerve	0.005	0.995	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.005	0.995	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.005	0.995	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.005	0.995	0.000
S95.2 Injury of dorsal vein of foot	0.005	0.995	0.000
S95.1 Injury of plantar artery of foot	0.005	0.995	0.000
S95.0 Injury of dorsal artery of foot	0.005	0.995	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.005	0.995	0.000
S97.1 Crushing injury of toe(s)	0.005	0.995	0.000
S97.0 Crushing injury of ankle	0.005	0.995	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.005	0.995	0.000
S98.3 Traumatic amputation of other parts of foot	0.005	0.995	0.000
S98.2 Traumatic amputation of two or more toes	0.005	0.995	0.000
S98.1 Traumatic amputation of one toe	0.005	0.995	0.000
S98.0 Traumatic amputation of foot at ankle level	0.005	0.995	0.000
S92.91 Fracture of foot, unspecified (open)	0.005	0.995	0.000
S92.90 Fracture of foot, unspecified (closed)	0.005	0.995	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.995	0.005
S92.71 Multiple fractures of foot (open)	0.005	0.995	0.000
S90.0 Contusion of ankle	0.005	0.995	0.000
S92.70 Multiple fractures of foot (closed)	0.005	0.995	0.000
S93.0 Dislocation of ankle joint	0.005	0.995	0.000
S52.80 Fracture of other parts of forearm (closed)	0.005	0.995	0.000
S92.3 Fracture of metatarsal bone	0.005	0.995	0.000
S99.8 Other specified injuries of ankle and foot	0.005	0.995	0.000
S93.40 Sprain of unspecified ligament of ankle	0.005	0.995	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.995	0.005
S92.01 Fracture of calcaneus (open)	0.004	0.995	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.996	0.004
M25.46 Effusion of joint (Lower leg)	0.000	0.996	0.004
M25.4 Effusion of joint	0.000	0.996	0.004
R04 Haemorrhage from respiratory passages	0.000	0.996	0.004
S92.31 Fracture of metatarsal bone (open)	0.003	0.996	0.000
S92.00 Fracture of calcaneus (closed)	0.004	0.996	0.000
M25.47 Effusion of joint (Ankle and foot)	0.000	0.996	0.004
R04.8 Haemorrhage from other sites in respiratory passages	0.000	0.996	0.004
M89.9 Disorder of bone, unspecified	0.000	0.996	0.004
Z04.9 Examination and observation for unspecified reason	0.000	0.996	0.004
M25.43 Effusion of joint (Forearm)	0.000	0.997	0.003
M25.40 Effusion of joint (Multiple sites)	0.000	0.997	0.003
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
M25.42 Effusion of joint (Upper arm)	0.000	0.997	0.003
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.997	0.003
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
L90.5 Scar conditions and fibrosis of skin	0.000	0.997	0.003
M25.41 Effusion of joint (Shoulder region)	0.000	0.997	0.003
M25.49 Effusion of joint (Site unspecified)	0.000	0.997	0.003
M25.48 Effusion of joint (Other)	0.000	0.997	0.003
R04.9 Haemorrhage from respiratory passages, unspecified	0.000	0.997	0.003
R04.1 Haemorrhage from throat	0.000	0.997	0.003
M13.97 Arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
F01.9 Vascular dementia, unspecified	0.000	0.997	0.003
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.997	0.003
M00.9 Pyogenic arthritis, unspecified	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.997	0.003
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.997	0.003
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.997	0.003
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.997	0.003
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.997	0.003
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.003	0.997	0.000
M25.44 Effusion of joint (Hand)	0.000	0.997	0.003
Q66 Congenital deformities of feet	0.003	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.000	0.997	0.003
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.003	0.997	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.997	0.003
N43.3 Hydrocele, unspecified	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.003	0.997	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.997	0.002
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.002	0.997	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.997	0.002
G40.9 Epilepsy, unspecified	0.000	0.997	0.003
Q66.7 Pes cavus	0.002	0.997	0.000
L90.0 Lichen sclerosus et atrophicus	0.000	0.998	0.002
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.998	0.002
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.998	0.002
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.002	0.998	0.000
M89.8 Other specified disorders of bone	0.000	0.998	0.002
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.002	0.998	0.000
H16.0 Corneal ulcer	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.998	0.002
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.998	0.002
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.998	0.002
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.998	0.002
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.998	0.002
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.998	0.002
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
L90 Atrophic disorders of skin	0.000	0.998	0.002
M89 Other disorders of bone	0.000	0.998	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.998	0.002
M89.98 Disorder of bone, unspecified (Other)	0.000	0.998	0.002
M89.88 Other specified disorders of bone (Other)	0.000	0.998	0.002
D39.1 Ovary	0.002	0.998	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.998	0.002
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
F01 Vascular dementia	0.000	0.998	0.002
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
R04.2 Haemoptysis	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.998	0.002
H93.0 Degenerative and vascular disorders of ear	0.000	0.998	0.002
M25.36 Other instability of joint (Lower leg)	0.000	0.998	0.002
M25.3 Other instability of joint	0.000	0.998	0.002
M25 Other joint disorders, not elsewhere classified	0.000	0.998	0.002
H16.9 Keratitis, unspecified	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.000	0.998	0.002
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.998	0.002
M89.84 Other specified disorders of bone (Hand)	0.000	0.998	0.002
M89.83 Other specified disorders of bone (Forearm)	0.000	0.998	0.002
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.998	0.002
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
T47.4 Other laxatives	0.002	0.998	0.000
F02.0 Dementia in Pick's disease	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.998	0.002
H93.8 Other specified disorders of ear	0.000	0.998	0.002
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.998	0.002
M25.76 Osteophyte (Lower leg)	0.000	0.998	0.002
M25.9 Joint disorder, unspecified	0.000	0.998	0.002
M25.33 Other instability of joint (Forearm)	0.000	0.998	0.002
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.998	0.002
H93.3 Disorders of acoustic nerve	0.000	0.998	0.002
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
L90.9 Atrophic disorder of skin, unspecified	0.000	0.998	0.002
L90.8 Other atrophic disorders of skin	0.000	0.998	0.002
L90.6 Striae atrophicae	0.000	0.998	0.002
L90.4 Acrodermatitis chronica atrophicans	0.000	0.998	0.002
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.998	0.002
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.998	0.002
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.998	0.002
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.000	0.998	0.002
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.998	0.002
M89.2 Other disorders of bone development and growth	0.000	0.998	0.002
M89.1 Epiphyseal arrest	0.000	0.998	0.002
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M25.37 Other instability of joint (Ankle and foot)	0.000	0.998	0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.002
M89.3 Hypertrophy of bone	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
Q67.6 Pectus excavatum	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
H16 Keratitis	0.002	0.998	0.000
F01.8 Other vascular dementia	0.000	0.998	0.002
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.998	0.002
F01.2 Subcortical vascular dementia	0.000	0.998	0.002
F01.1 Multi-infarct dementia	0.000	0.998	0.002
F01.0 Vascular dementia of acute onset	0.000	0.998	0.002
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.000	0.998	0.002
K31.1 Adult hypertrophic pyloric stenosis	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M89.5 Osteolysis	0.000	0.998	0.002
T40.2 Other opioids	0.002	0.998	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.998	0.002
M25.39 Other instability of joint (Site unspecified)	0.000	0.998	0.002
M25.38 Other instability of joint (Other)	0.000	0.998	0.002
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.998	0.002
M25.32 Other instability of joint (Upper arm)	0.000	0.998	0.002
M25.30 Other instability of joint (Multiple sites)	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.001	0.998	0.000
M25.2 Flail joint	0.000	0.998	0.002
M25.1 Fistula of joint	0.000	0.998	0.002
Y84.8 Other medical procedures	0.000	0.998	0.002
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.998	0.002
Q83.1 Accessory breast	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.998	0.002
Z47.8 Other specified orthopaedic follow-up care	0.000	0.998	0.002
Q83 Congenital malformations of breast	0.002	0.998	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
Q21.1 Atrial septal defect	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.998	0.002
M00 Pyogenic arthritis	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.000	0.998	0.002
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
R10.4 Other and unspecified abdominal pain	0.000	0.998	0.002
F00 Dementia in Alzheimer's disease	0.000	0.998	0.002
M25.31 Other instability of joint (Shoulder region)	0.000	0.998	0.002
M86.98 Osteomyelitis, unspecified (Other)	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
M25.72 Osteophyte (Upper arm)	0.000	0.998	0.002
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.998	0.002
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.998	0.001
M25.98 Joint disorder, unspecified (Other)	0.000	0.998	0.001
M25.94 Joint disorder, unspecified (Hand)	0.000	0.998	0.002
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.998	0.001
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.998	0.001
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.998	0.001
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
N90.7 Vulvar cyst	0.000	0.998	0.002
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.998	0.001
M89.18 Epiphyseal arrest (Other)	0.000	0.998	0.001
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.998	0.001
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.998	0.001
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.998	0.001
M89.14 Epiphyseal arrest (Hand)	0.000	0.998	0.001
M89.13 Epiphyseal arrest (Forearm)	0.000	0.998	0.001
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.998	0.001
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.998	0.001
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.998	0.001
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.998	0.001
M89.28 Other disorders of bone development and growth (Other)	0.000	0.998	0.001
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.998	0.001
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.998	0.001
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.998	0.001
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.998	0.001
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.998	0.001
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.998	0.001
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.998	0.001
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.998	0.001
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.998	0.001
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.998	0.001
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.998	0.001
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.998	0.001
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.998	0.001
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.998	0.001
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.998	0.001
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.998	0.001
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.998	0.001
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.998	0.001
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.998	0.001
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.998	0.001
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.998	0.001
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.998	0.001
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.998	0.001
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.998	0.001
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.998	0.001
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.998	0.001
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.998	0.001
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.998	0.001
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
T46.7 Peripheral vasodilators	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.998	0.002
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.998	0.001
M89.38 Hypertrophy of bone (Other)	0.000	0.998	0.001
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.998	0.001
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.998	0.001
M89.34 Hypertrophy of bone (Hand)	0.000	0.998	0.001
M89.33 Hypertrophy of bone (Forearm)	0.000	0.998	0.001
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.998	0.001
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.998	0.001
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.998	0.001
M25.7 Osteophyte	0.000	0.998	0.002
M25.0 Haemarthrosis	0.000	0.998	0.001
H16.8 Other keratitis	0.001	0.998	0.000
H16.4 Corneal neovascularisation	0.001	0.998	0.000
H16.3 Interstitial and deep keratitis	0.001	0.998	0.000
M89.0 Algoneurodystrophy	0.000	0.998	0.001
N89.5 Stricture and atresia of vagina	0.000	0.998	0.002
Q83.8 Other congenital malformations of breast	0.001	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
M25.8 Other specified joint disorders	0.000	0.998	0.002
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.998	0.001
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.998	0.002
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000
Q68.3 Congenital bowing of femur	0.001	0.998	0.000
Q68.2 Congenital deformity of knee	0.001	0.998	0.000
Q68.1 Congenital deformity of hand	0.001	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.998	0.000
Q69.9 Polydactyly, unspecified	0.001	0.998	0.000
Q69.2 Accessory toe(s)	0.001	0.998	0.000
Q69.1 Accessory thumb(s)	0.001	0.998	0.000
Q69.0 Accessory finger(s)	0.001	0.998	0.000
Q70.9 Syndactyly, unspecified	0.001	0.998	0.000
Q70.4 Polysyndactyly	0.001	0.998	0.000
Q70.3 Webbed toes	0.001	0.998	0.000
Q70.2 Fused toes	0.001	0.998	0.000
Q70.1 Webbed fingers	0.001	0.998	0.000
Q70.0 Fused fingers	0.001	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.998	0.000
Q71.6 Lobster-claw hand	0.001	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.998	0.000
Q72.7 Split foot	0.001	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.001	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.001	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.001	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.001	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.001	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.001	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.001	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.001	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.001	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.001	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.998	0.000
Q75.3 Macrocephaly	0.001	0.998	0.000
Q75.2 Hypertelorism	0.001	0.998	0.000
Q75.1 Craniofacial dysostosis	0.001	0.998	0.000
Q75.0 Craniosynostosis	0.001	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.998	0.000
Q77.5 Diastrophic dysplasia	0.001	0.998	0.000
Q77.4 Achondroplasia	0.001	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.998	0.000
Q77.2 Short rib syndrome	0.001	0.998	0.000
Q77.1 Thanatophoric short stature	0.001	0.998	0.000
Q77.0 Achondrogenesis	0.001	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.998	0.000
M25.19 Fistula of joint (Site unspecified)	0.000	0.998	0.001
M25.18 Fistula of joint (Other)	0.000	0.998	0.001
M25.17 Fistula of joint (Ankle and foot)	0.000	0.998	0.001
M25.16 Fistula of joint (Lower leg)	0.000	0.998	0.001
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.998	0.001
M25.14 Fistula of joint (Hand)	0.000	0.998	0.001
M25.13 Fistula of joint (Forearm)	0.000	0.998	0.001
M25.12 Fistula of joint (Upper arm)	0.000	0.998	0.001
M25.11 Fistula of joint (Shoulder region)	0.000	0.998	0.001
M25.10 Fistula of joint (Multiple sites)	0.000	0.998	0.001
M25.29 Flail joint (Site unspecified)	0.000	0.998	0.001
M25.28 Flail joint (Other)	0.000	0.998	0.001
M25.27 Flail joint (Ankle and foot)	0.000	0.998	0.001
M25.26 Flail joint (Lower leg)	0.000	0.998	0.001
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.998	0.001
M25.24 Flail joint (Hand)	0.000	0.998	0.001
M25.23 Flail joint (Forearm)	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations