TreeWAS – Variant ID: rs10519227

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.9 Non-toxic goitre, unspecified	1.000	0.000	0.000
E04.2 Non-toxic multinodular goitre	1.000	0.000	0.000
E04 Other non-toxic goitre	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.999	0.001	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.996	0.004	0.000
E07 Other disorders of thyroid	0.943	0.057	0.000
E04.1 Non-toxic single thyroid nodule	0.932	0.068	0.000
E05.9 Thyrotoxicosis, unspecified	0.926	0.074	0.000
E04.0 Non-toxic diffuse goitre	0.915	0.085	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.903	0.097	0.000
E06 Thyroiditis	0.898	0.102	0.000
E07.9 Disorder of thyroid, unspecified	0.887	0.113	0.000
E06.3 Autoimmune thyroiditis	0.812	0.188	0.000
E07.8 Other specified disorders of thyroid	0.751	0.249	0.000
E04.8 Other specified non-toxic goitre	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.716	0.284	0.000
E05.4 Thyrotoxicosis factitia	0.716	0.284	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.716	0.284	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.716	0.284	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.710	0.290	0.000
E06.9 Thyroiditis, unspecified	0.682	0.318	0.000
E05.8 Other thyrotoxicosis	0.680	0.319	0.000
E07.1 Dyshormogenetic goitre	0.676	0.324	0.000
E07.0 Hypersecretion of calcitonin	0.676	0.324	0.000
E06.5 Other chronic thyroiditis	0.644	0.356	0.000
E06.4 Drug-induced thyroiditis	0.644	0.356	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.644	0.356	0.000
E06.1 Subacute thyroiditis	0.644	0.356	0.000
E06.0 Acute thyroiditis	0.644	0.356	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E89.0 Postprocedural hypothyroidism	0.405	0.595	0.000
E03 Other hypothyroidism	0.274	0.726	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.254	0.746	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.211	0.789	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.209	0.791	0.000
N35.9 Urethral stricture, unspecified	0.000	0.801	0.199
E03.5 Myxoedema coma	0.196	0.803	0.000
E03.4 Atrophy of thyroid (acquired)	0.196	0.803	0.000
E03.3 Postinfectious hypothyroidism	0.196	0.803	0.000
E03.1 Congenital hypothyroidism without goitre	0.196	0.803	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.196	0.803	0.000
E89.4 Postprocedural ovarian failure	0.184	0.816	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.182	0.818	0.000
E89.5 Postprocedural testicular hypofunction	0.182	0.818	0.000
E89.1 Postprocedural hypoinsulinaemia	0.182	0.818	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.181	0.819	0.000
E89.3 Postprocedural hypopituitarism	0.178	0.822	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.154	0.846	0.000
E89.2 Postprocedural hypoparathyroidism	0.154	0.846	0.000
E70-E90 Metabolic disorders	0.133	0.867	0.000
E20-E35 Disorders of other endocrine glands	0.131	0.869	0.000
E34 Other endocrine disorders	0.113	0.887	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.113	0.887	0.000
E22 Hyperfunction of pituitary gland	0.111	0.889	0.000
E50-E64 Other nutritional deficiencies	0.107	0.893	0.000
E22.1 Hyperprolactinaemia	0.104	0.896	0.000
E40-E46 Malnutrition	0.104	0.896	0.000
E34.0 Carcinoid syndrome	0.101	0.899	0.000
E23 Hypofunction and other disorders of pituitary gland	0.099	0.901	0.000
E25 Adrenogenital disorders	0.099	0.901	0.000
E84 Cystic fibrosis	0.096	0.904	0.000
E77 Disorders of glycoprotein metabolism	0.096	0.904	0.000
E76 Disorders of glycosaminoglycan metabolism	0.096	0.904	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.096	0.904	0.000
E72 Other disorders of amino-acid metabolism	0.096	0.904	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.096	0.904	0.000
E70 Disorders of aromatic amino-acid metabolism	0.096	0.904	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.096	0.904	0.000
E28 Ovarian dysfunction	0.095	0.905	0.000
E34.8 Other specified endocrine disorders	0.094	0.906	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.094	0.906	0.000
E32 Diseases of thymus	0.094	0.906	0.000
E31 Polyglandular dysfunction	0.094	0.906	0.000
E30 Disorders of puberty, not elsewhere classified	0.094	0.906	0.000
N35 Urethral stricture	0.000	0.907	0.093
E85 Amyloidosis	0.092	0.908	0.000
E74 Other disorders of carbohydrate metabolism	0.092	0.908	0.000
E03.8 Other specified hypothyroidism	0.090	0.909	0.001
E21.0 Primary hyperparathyroidism	0.091	0.909	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.090	0.910	0.000
E79 Disorders of purine and pyrimidine metabolism	0.090	0.910	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.088	0.912	0.000
E21.2 Other hyperparathyroidism	0.087	0.912	0.000
E26 Hyperaldosteronism	0.087	0.913	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.087	0.913	0.000
E20 Hypoparathyroidism	0.086	0.914	0.000
E21.4 Other specified disorders of parathyroid gland	0.084	0.915	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.084	0.916	0.000
E29 Testicular dysfunction	0.083	0.917	0.000
E27 Other disorders of adrenal gland	0.082	0.918	0.000
E34.5 Androgen resistance syndrome	0.081	0.919	0.000
E34.4 Constitutional tall stature	0.081	0.919	0.000
E34.3 Short stature, not elsewhere classified	0.081	0.919	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.081	0.919	0.000
E34.1 Other hypersecretion of intestinal hormones	0.081	0.919	0.000
E73 Lactose intolerance	0.081	0.919	0.000
E56 Other vitamin deficiencies	0.081	0.919	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.079	0.920	0.000
E22.8 Other hyperfunction of pituitary gland	0.079	0.920	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.077	0.923	0.000
E63 Other nutritional deficiencies	0.077	0.923	0.000
E51 Thiamine deficiency	0.077	0.923	0.000
E50 Vitamin A deficiency	0.077	0.923	0.000
E60 Dietary zinc deficiency	0.077	0.923	0.000
E59 Dietary selenium deficiency	0.077	0.923	0.000
E58 Dietary calcium deficiency	0.077	0.923	0.000
E54 Ascorbic acid deficiency	0.077	0.923	0.000
E52 Niacin deficiency [pellagra]	0.077	0.923	0.000
E61 Deficiency of other nutrient elements	0.077	0.923	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.076	0.924	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.075	0.925	0.000
E45 Retarded development following protein-energy malnutrition	0.075	0.925	0.000
E43 Unspecified severe protein-energy malnutrition	0.075	0.925	0.000
E42 Marasmic kwashiorkor	0.075	0.925	0.000
E41 Nutritional marasmus	0.075	0.925	0.000
E40 Kwashiorkor	0.075	0.925	0.000
E23.0 Hypopituitarism	0.074	0.926	0.000
E85.8 Other amyloidosis	0.074	0.926	0.000
E23.7 Disorder of pituitary gland, unspecified	0.074	0.926	0.000
E55 Vitamin D deficiency	0.073	0.927	0.000
E88 Other metabolic disorders	0.073	0.927	0.000
E53 Deficiency of other B group vitamins	0.073	0.927	0.000
E23.2 Diabetes insipidus	0.073	0.927	0.000
E85.4 Organ-limited amyloidosis	0.072	0.928	0.000
N35.8 Other urethral stricture	0.000	0.928	0.072
E80.2 Other porphyria	0.071	0.929	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.071	0.929	0.000
E23.1 Drug-induced hypopituitarism	0.071	0.929	0.000
E28.2 Polycystic ovarian syndrome	0.071	0.929	0.000
E25.9 Adrenogenital disorder, unspecified	0.071	0.929	0.000
E25.8 Other adrenogenital disorders	0.071	0.929	0.000
E23.6 Other disorders of pituitary gland	0.069	0.931	0.000
E22.0 Acromegaly and pituitary gigantism	0.069	0.931	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.069	0.931	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.069	0.931	0.000
E70.3 Albinism	0.069	0.931	0.000
E70.2 Disorders of tyrosine metabolism	0.069	0.931	0.000
E70.1 Other hyperphenylalaninaemias	0.069	0.931	0.000
E70.0 Classical phenylketonuria	0.069	0.931	0.000
E71.3 Disorders of fatty-acid metabolism	0.069	0.931	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.069	0.931	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.069	0.931	0.000
E71.0 Maple-syrup-urine disease	0.069	0.931	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.069	0.931	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.069	0.931	0.000
E72.5 Disorders of glycine metabolism	0.069	0.931	0.000
E72.4 Disorders of ornithine metabolism	0.069	0.931	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.069	0.931	0.000
E72.2 Disorders of urea cycle metabolism	0.069	0.931	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.069	0.931	0.000
E72.0 Disorders of amino-acid transport	0.069	0.931	0.000
E75.6 Lipid storage disorder, unspecified	0.069	0.931	0.000
E75.5 Other lipid storage disorders	0.069	0.931	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.069	0.931	0.000
E75.3 Sphingolipidosis, unspecified	0.069	0.931	0.000
E75.2 Other sphingolipidosis	0.069	0.931	0.000
E75.1 Other gangliosidosis	0.069	0.931	0.000
E75.0 GM2 gangliosidosis	0.069	0.931	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.069	0.931	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.069	0.931	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.069	0.931	0.000
E76.2 Other mucopolysaccharidoses	0.069	0.931	0.000
E76.1 Mucopolysaccharidosis, type II	0.069	0.931	0.000
E76.0 Mucopolysaccharidosis, type I	0.069	0.931	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.069	0.931	0.000
E77.8 Other disorders of glycoprotein metabolism	0.069	0.931	0.000
E77.1 Defects in glycoprotein degradation	0.069	0.931	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.069	0.931	0.000
E84.9 Cystic fibrosis, unspecified	0.069	0.931	0.000
E84.8 Cystic fibrosis with other manifestations	0.069	0.931	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.069	0.931	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.069	0.931	0.000
E83 Disorders of mineral metabolism	0.069	0.931	0.000
E46 Unspecified protein-energy malnutrition	0.068	0.931	0.000
E28.9 Ovarian dysfunction, unspecified	0.068	0.932	0.000
E28.8 Other ovarian dysfunction	0.068	0.932	0.000
E28.1 Androgen excess	0.068	0.932	0.000
E28.0 Oestrogen excess	0.068	0.932	0.000
E30.9 Disorder of puberty, unspecified	0.067	0.932	0.000
E30.8 Other disorders of puberty	0.067	0.932	0.000
E30.1 Precocious puberty	0.067	0.932	0.000
E30.0 Delayed puberty	0.067	0.932	0.000
E31.9 Polyglandular dysfunction, unspecified	0.067	0.932	0.000
E31.8 Other polyglandular dysfunction	0.067	0.932	0.000
E31.1 Polyglandular hyperfunction	0.067	0.932	0.000
E31.0 Autoimmune polyglandular failure	0.067	0.932	0.000
E32.9 Disease of thymus, unspecified	0.067	0.932	0.000
E32.8 Other diseases of thymus	0.067	0.932	0.000
E32.1 Abscess of thymus	0.067	0.932	0.000
E32.0 Persistent hyperplasia of thymus	0.067	0.932	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.067	0.932	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.067	0.932	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.067	0.932	0.000
N35.1 Postinfective urethral stricture, not elsewhere classified	0.000	0.933	0.067
N35.0 Posttraumatic urethral stricture	0.000	0.933	0.067
E85.2 Heredofamilial amyloidosis, unspecified	0.066	0.933	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.066	0.933	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.066	0.933	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.066	0.934	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.066	0.934	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.066	0.934	0.000
E74.2 Disorders of galactose metabolism	0.066	0.934	0.000
E74.1 Disorders of fructose metabolism	0.066	0.934	0.000
E74.0 Glycogen storage disease	0.066	0.934	0.000
E28.3 Primary ovarian failure	0.065	0.935	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.064	0.935	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.064	0.935	0.000
E79.1 Lesch-Nyhan syndrome	0.064	0.935	0.000
E27.1 Primary adrenocortical insufficiency	0.064	0.936	0.000
E21.3 Hyperparathyroidism, unspecified	0.064	0.936	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.063	0.937	0.000
E26.9 Hyperaldosteronism, unspecified	0.062	0.937	0.000
E26.8 Other hyperaldosteronism	0.062	0.937	0.000
E26.1 Secondary hyperaldosteronism	0.062	0.937	0.000
E15 Nondiabetic hypoglycaemic coma	0.062	0.938	0.000
E20.8 Other hypoparathyroidism	0.062	0.938	0.000
E20.1 Pseudohypoparathyroidism	0.062	0.938	0.000
E20.0 Idiopathic hypoparathyroidism	0.062	0.938	0.000
E56.1 Deficiency of vitamin K	0.062	0.938	0.000
E24 Cushing's syndrome	0.061	0.938	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.061	0.939	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.060	0.940	0.000
E80.5 Crigler-Najjar syndrome	0.060	0.940	0.000
E80.3 Defects of catalase and peroxydase	0.060	0.940	0.000
E80.1 Porphyria cutanea tarda	0.060	0.940	0.000
E80.0 Hereditary erythropoietic porphyria	0.060	0.940	0.000
E83.3 Disorders of phosphorus metabolism	0.060	0.940	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.060	0.940	0.000
E53.9 Vitamin B deficiency, unspecified	0.060	0.940	0.000
E29.9 Testicular dysfunction, unspecified	0.060	0.940	0.000
E29.8 Other testicular dysfunction	0.060	0.940	0.000
E29.0 Testicular hyperfunction	0.060	0.940	0.000
E34.9 Endocrine disorder, unspecified	0.059	0.940	0.000
E27.5 Adrenomedullary hyperfunction	0.059	0.941	0.000
E27.0 Other adrenocortical overactivity	0.059	0.941	0.000
E73.8 Other lactose intolerance	0.058	0.942	0.000
E73.1 Secondary lactase deficiency	0.058	0.942	0.000
E73.0 Congenital lactase deficiency	0.058	0.942	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.058	0.942	0.000
E80.6 Other disorders of bilirubin metabolism	0.058	0.942	0.000
E56.9 Vitamin deficiency, unspecified	0.058	0.942	0.000
E56.8 Deficiency of other vitamins	0.058	0.942	0.000
E56.0 Deficiency of vitamin E	0.058	0.942	0.000
E85.3 Secondary systemic amyloidosis	0.057	0.942	0.000
E27.2 Addisonian crisis	0.057	0.943	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.056	0.944	0.000
E61.1 Iron deficiency	0.056	0.944	0.000
E27.8 Other specified disorders of adrenal gland	0.056	0.944	0.000
E26.0 Primary hyperaldosteronism	0.055	0.944	0.000
E50.9 Vitamin A deficiency, unspecified	0.055	0.945	0.000
E50.8 Other manifestations of vitamin A deficiency	0.055	0.945	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.055	0.945	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.055	0.945	0.000
E50.5 Vitamin A deficiency with night blindness	0.055	0.945	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.055	0.945	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.055	0.945	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.055	0.945	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.055	0.945	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.055	0.945	0.000
E51.9 Thiamine deficiency, unspecified	0.055	0.945	0.000
E51.8 Other manifestations of thiamine deficiency	0.055	0.945	0.000
E51.2 Wernicke's encephalopathy	0.055	0.945	0.000
E51.1 Beriberi	0.055	0.945	0.000
E63.9 Nutritional deficiency, unspecified	0.055	0.945	0.000
E63.8 Other specified nutritional deficiencies	0.055	0.945	0.000
E63.1 Imbalance of constituents of food intake	0.055	0.945	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.055	0.945	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.055	0.945	0.000
E64.8 Sequelae of other nutritional deficiencies	0.055	0.945	0.000
E64.3 Sequelae of rickets	0.055	0.945	0.000
E64.2 Sequelae of vitamin C deficiency	0.055	0.945	0.000
E64.1 Sequelae of vitamin A deficiency	0.055	0.945	0.000
E64.0 Sequelae of protein-energy malnutrition	0.055	0.945	0.000
E61.9 Deficiency of nutrient element, unspecified	0.055	0.945	0.000
E61.8 Deficiency of other specified nutrient elements	0.055	0.945	0.000
E61.7 Deficiency of multiple nutrient elements	0.055	0.945	0.000
E61.6 Vanadium deficiency	0.055	0.945	0.000
E61.5 Molybdenum deficiency	0.055	0.945	0.000
E61.4 Chromium deficiency	0.055	0.945	0.000
E61.3 Manganese deficiency	0.055	0.945	0.000
E61.0 Copper deficiency	0.055	0.945	0.000
E83.4 Disorders of magnesium metabolism	0.055	0.945	0.000
E27.9 Disorder of adrenal gland, unspecified	0.055	0.945	0.000
E61.2 Magnesium deficiency	0.055	0.945	0.000
E65-E68 Obesity and other hyperalimentation	0.054	0.945	0.000
E44.1 Mild protein-energy malnutrition	0.054	0.946	0.000
E44.0 Moderate protein-energy malnutrition	0.054	0.946	0.000
E88.8 Other specified metabolic disorders	0.054	0.946	0.000
E20.9 Hypoparathyroidism, unspecified	0.054	0.946	0.000
E85.9 Amyloidosis, unspecified	0.053	0.947	0.000
E88.2 Lipomatosis, not elsewhere classified	0.053	0.947	0.000
E88.9 Metabolic disorder, unspecified	0.053	0.947	0.000
E55.0 Rickets, active	0.053	0.947	0.000
E88.3 Tumour lysis syndrome	0.052	0.947	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.052	0.947	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.053	0.947	0.000
E53.1 Pyridoxine deficiency	0.052	0.947	0.000
E53.0 Riboflavin deficiency	0.052	0.947	0.000
E83.8 Other disorders of mineral metabolism	0.050	0.950	0.000
E83.2 Disorders of zinc metabolism	0.050	0.950	0.000
E83.0 Disorders of copper metabolism	0.050	0.950	0.000
E29.1 Testicular hypofunction	0.049	0.951	0.000
E55.9 Vitamin D deficiency, unspecified	0.049	0.951	0.000
E24.8 Other Cushing's syndrome	0.044	0.956	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.044	0.956	0.000
E24.3 Ectopic ACTH syndrome	0.044	0.956	0.000
E24.1 Nelson's syndrome	0.044	0.956	0.000
E73.9 Lactose intolerance, unspecified	0.043	0.956	0.000
E24.2 Drug-induced Cushing's syndrome	0.040	0.960	0.000
E67 Other hyperalimentation	0.039	0.961	0.000
E68 Sequelae of hyperalimentation	0.039	0.961	0.000
E24.0 Pituitary-dependent Cushing's disease	0.038	0.962	0.000
E16 Other disorders of pancreatic internal secretion	0.038	0.962	0.000
E53.8 Deficiency of other specified B group vitamins	0.035	0.965	0.000
E24.9 Cushing's syndrome, unspecified	0.032	0.968	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.971	0.029
E67.8 Other specified hyperalimentation	0.028	0.971	0.000
E67.3 Hypervitaminosis D	0.028	0.971	0.000
E67.2 Megavitamin-B6 syndrome	0.028	0.971	0.000
E67.1 Hypercarotenaemia	0.028	0.971	0.000
E67.0 Hypervitaminosis A	0.028	0.971	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.027	0.972	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.027	0.972	0.000
E16.4 Abnormal secretion of gastrin	0.027	0.972	0.000
E16.3 Increased secretion of glucagon	0.027	0.972	0.000
E16.1 Other hypoglycaemia	0.027	0.973	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.026	0.974	0.000
L89 Decubitus ulcer	0.000	0.975	0.025
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.024	0.975	0.000
E65 Localised adiposity	0.024	0.976	0.000
L89.1 Stage II decubitus ulcer	0.000	0.976	0.024
L89.2 Stage III decubitus ulcer	0.000	0.977	0.023
E80.4 Gilbert's syndrome	0.022	0.978	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.980	0.020
E66 Obesity	0.019	0.981	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.017	0.983	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.983	0.017
E66.2 Extreme obesity with alveolar hypoventilation	0.014	0.985	0.000
C50.9 Breast, unspecified	0.014	0.986	0.000
E66.1 Drug-induced obesity	0.014	0.986	0.000
E66.8 Other obesity	0.013	0.987	0.000
E66.0 Obesity due to excess calories	0.011	0.988	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.990	0.010
E16.2 Hypoglycaemia, unspecified	0.010	0.990	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.009	0.991	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.991	0.009
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.008	0.992	0.000
E10-E14 Diabetes mellitus	0.007	0.993	0.000
C82.3 Follicular lymphoma grade IIIa	0.007	0.993	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.007	0.993	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.007	0.993	0.000
C82.6 Cutaneous follicle centre lymphoma	0.007	0.993	0.000
C82.5 Diffuse follicle centre lymphoma	0.007	0.993	0.000
C82.4 Follicular lymphoma grade IIIb	0.007	0.993	0.000
C82.0 Small cleaved cell, follicular	0.007	0.993	0.000
Y83.3 Surgical operation with formation of external stoma	0.007	0.993	0.000
C50.2 Upper-inner quadrant of breast	0.007	0.993	0.000
C82.2 Large cell, follicular	0.006	0.994	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.006	0.994	0.000
E83.1 Disorders of iron metabolism	0.005	0.994	0.001
E78.4 Other hyperlipidaemia	0.006	0.994	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.006	0.994	0.000
E78.2 Mixed hyperlipidaemia	0.006	0.994	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.995	0.005
E12 Malnutrition-related diabetes mellitus	0.005	0.995	0.000
E78.3 Hyperchylomicronaemia	0.005	0.995	0.000
J69.0 Pneumonitis due to food and vomit	0.005	0.995	0.000
E78.6 Lipoprotein deficiency	0.005	0.995	0.000
E78.1 Pure hyperglyceridaemia	0.005	0.995	0.000
E03.9 Hypothyroidism, unspecified	0.005	0.995	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.996	0.004
G30.9 Alzheimer's disease, unspecified	0.004	0.996	0.000
E86 Volume depletion	0.004	0.996	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.004	0.996	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.996	0.004
J69 Pneumonitis due to solids and liquids	0.004	0.996	0.000
E12.9 Without complications	0.004	0.996	0.000
E12.8 With unspecified complications	0.004	0.996	0.000
E12.7 With multiple complications	0.004	0.996	0.000
E12.6 With other specified complications	0.004	0.996	0.000
E12.5 With peripheral circulatory complications	0.004	0.996	0.000
E12.4 With neurological complications	0.004	0.996	0.000
E12.3 With ophthalmic complications	0.004	0.996	0.000
E12.2 With renal complications	0.004	0.996	0.000
E12.1 With ketoacidosis	0.004	0.996	0.000
E12.0 With coma	0.004	0.996	0.000
E13 Other specified diabetes mellitus	0.003	0.996	0.001
M47.80 Other spondylosis (Multiple sites in spine)	0.004	0.996	0.000
M62.8 Other specified disorders of muscle	0.004	0.996	0.000
F00 Dementia in Alzheimer's disease	0.004	0.996	0.000
E83.5 Disorders of calcium metabolism	0.004	0.996	0.000
N99.5 Malfunction of external stoma of urinary tract	0.000	0.996	0.004
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.996	0.004
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.004	0.996	0.000
C50 Malignant neoplasm of breast	0.004	0.996	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.996	0.004
N99.2 Postprocedural adhesions of vagina	0.000	0.996	0.004
N99.0 Postprocedural renal failure	0.000	0.996	0.004
D69 Purpura and other haemorrhagic conditions	0.000	0.996	0.004
J69.8 Pneumonitis due to other solids and liquids	0.004	0.996	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.996	0.004
M62.81 Other specified disorders of muscle (Shoulder region)	0.004	0.996	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.004	0.996	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.004	0.996	0.000
F02 Dementia in other diseases classified elsewhere	0.004	0.996	0.000
O02.1 Missed abortion	0.004	0.996	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.997	0.003
F02.3 Dementia in Parkinson's disease	0.003	0.997	0.000
F02.0 Dementia in Pick's disease	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.000	0.997	0.003
J69.1 Pneumonitis due to oils and essences	0.003	0.997	0.000
M62.84 Other specified disorders of muscle (Hand)	0.003	0.997	0.000
E13.8 With unspecified complications	0.003	0.997	0.001
E13.7 With multiple complications	0.003	0.997	0.001
E13.6 With other specified complications	0.003	0.997	0.001
E13.5 With peripheral circulatory complications	0.003	0.997	0.001
E13.4 With neurological complications	0.003	0.997	0.001
E13.3 With ophthalmic complications	0.003	0.997	0.001
E13.2 With renal complications	0.003	0.997	0.001
E13.1 With ketoacidosis	0.003	0.997	0.001
E13.0 With coma	0.003	0.997	0.001
M62.87 Other specified disorders of muscle (Ankle and foot)	0.003	0.997	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.003	0.997	0.000
D69.0 Allergic purpura	0.000	0.997	0.003
F00.1 Dementia in Alzheimer's disease with late onset	0.003	0.997	0.000
G30 Alzheimer's disease	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.003	0.997	0.000
C50.6 Axillary tail of breast	0.003	0.997	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.003	0.997	0.000
Z03.1 Observation for suspected malignant neoplasm	0.003	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.003	0.997	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.003	0.997	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.003	0.997	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.997	0.003
D69.2 Other nonthrombocytopenic purpura	0.000	0.997	0.003
D69.1 Qualitative platelet defects	0.000	0.997	0.003
D69.5 Secondary thrombocytopenia	0.000	0.997	0.003
Z43.3 Attention to colostomy	0.003	0.997	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.003	0.997	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.003	0.997	0.000
M62.88 Other specified disorders of muscle (Other)	0.003	0.997	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.003	0.997	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.997	0.003
A49.0 Staphylococcal infection, unspecified	0.000	0.997	0.003
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.003	0.997	0.000
F02.2 Dementia in Huntington's disease	0.003	0.997	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.003	0.997	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.997	0.003
J60-J70 Lung diseases due to external agents	0.003	0.997	0.000
M25.76 Osteophyte (Lower leg)	0.003	0.997	0.000
E78.8 Other disorders of lipoprotein metabolism	0.002	0.997	0.001
C50.0 Nipple and areola	0.003	0.997	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.997	0.003
N99.1 Postprocedural urethral stricture	0.000	0.997	0.003
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.997	0.003
G31.8 Other specified degenerative diseases of nervous system	0.003	0.997	0.000
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.997	0.003
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
N73.6 Female pelvic peritoneal adhesions	0.003	0.997	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.003	0.997	0.000
J70 Respiratory conditions due to other external agents	0.003	0.997	0.000
M62 Other disorders of muscle	0.003	0.997	0.000
G30.1 Alzheimer's disease with late onset	0.002	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.997	0.000
G30-G32 Other degenerative diseases of the nervous system	0.002	0.997	0.000
G30.8 Other Alzheimer's disease	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.998	0.000
J67.2 Bird fancier's lung	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
J64 Unspecified pneumoconiosis	0.002	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.002	0.998	0.000
J70.0 Acute pulmonary manifestations due to radiation	0.002	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.998	0.002
F09 Unspecified organic or symptomatic mental disorder	0.002	0.998	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.002	0.998	0.000
M62.6 Muscle strain	0.002	0.998	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.002	0.998	0.000
J66 Airway disease due to specific organic dust	0.002	0.998	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations