TreeWAS – Variant ID: rs1076160

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.57 Pain in joint (Ankle and foot)	0.043	0.957	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.984	0.016
G30 Alzheimer's disease	0.000	0.985	0.015
G30.0 Alzheimer's disease with early onset	0.000	0.986	0.014
G30.8 Other Alzheimer's disease	0.000	0.988	0.012
G31.8 Other specified degenerative diseases of nervous system	0.000	0.988	0.012
G30-G32 Other degenerative diseases of the nervous system	0.000	0.989	0.011
M19.04 Primary arthrosis of other joints (Hand)	0.011	0.989	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.989	0.011
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.989	0.011
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.991	0.009
G31.2 Degeneration of nervous system due to alcohol	0.000	0.991	0.009
M19.01 Primary arthrosis of other joints (Shoulder region)	0.009	0.991	0.000
M19.0 Primary arthrosis of other joints	0.009	0.991	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.992	0.008
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.992	0.008
R44.1 Visual hallucinations	0.000	0.992	0.008
M19.09 Primary arthrosis of other joints (Site unspecified)	0.007	0.993	0.000
M35.0 Sicca syndrome [Sjogren]	0.007	0.993	0.000
G31.0 Circumscribed brain atrophy	0.000	0.993	0.007
M19.00 Primary arthrosis of other joints (Multiple sites)	0.007	0.993	0.000
M19.08 Primary arthrosis of other joints (Other)	0.007	0.993	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.993	0.007
J32.4 Chronic pansinusitis	0.007	0.993	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.007	0.993	0.000
M54.22 Cervicalgia (Cervical region)	0.007	0.993	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.006	0.994	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.994	0.006
Z57.5 Occupational exposure to toxic agents in other industries	0.006	0.994	0.000
F20 Schizophrenia	0.000	0.994	0.006
R45.2 Unhappiness	0.000	0.994	0.006
Q21.1 Atrial septal defect	0.000	0.994	0.006
R45 Symptoms and signs involving emotional state	0.000	0.994	0.006
Q27.3 Peripheral arteriovenous malformation	0.000	0.994	0.006
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.994	0.006
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.006	0.994	0.000
F20.0 Paranoid schizophrenia	0.000	0.994	0.006
F29 Unspecified nonorganic psychosis	0.000	0.995	0.005
F20.5 Residual schizophrenia	0.000	0.995	0.005
F20.9 Schizophrenia, unspecified	0.000	0.995	0.005
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.995	0.005
N92.1 Excessive and frequent menstruation with irregular cycle	0.005	0.995	0.000
R59.9 Enlarged lymph nodes, unspecified	0.000	0.995	0.005
Q27 Other congenital malformations of peripheral vascular system	0.000	0.995	0.005
F22 Persistent delusional disorders	0.000	0.995	0.005
F25 Schizoaffective disorders	0.000	0.995	0.005
Z57.3 Occupational exposure to other air contaminants	0.005	0.995	0.000
R45.5 Hostility	0.000	0.995	0.005
Q21 Congenital malformations of cardiac septa	0.000	0.995	0.005
F20.2 Catatonic schizophrenia	0.000	0.995	0.005
Z57 Occupational exposure to risk-factors	0.005	0.995	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.004	0.995	0.000
F20.6 Simple schizophrenia	0.000	0.995	0.004
F20.4 Postschizophrenic depression	0.000	0.995	0.004
F20.3 Undifferentiated schizophrenia	0.000	0.995	0.004
F20.1 Hebephrenic schizophrenia	0.000	0.995	0.004
M19.03 Primary arthrosis of other joints (Forearm)	0.004	0.995	0.000
K61.0 Anal abscess	0.005	0.995	0.000
F23 Acute and transient psychotic disorders	0.000	0.995	0.005
F25.1 Schizoaffective disorder, depressive type	0.000	0.996	0.004
F22.0 Delusional disorder	0.000	0.996	0.004
R45.7 State of emotional shock and stress, unspecified	0.000	0.996	0.004
M48.02 Spinal stenosis (Cervical region)	0.000	0.996	0.004
Z50.5 Speech therapy	0.000	0.996	0.004
R45.3 Demoralisation and apathy	0.000	0.996	0.004
F20.8 Other schizophrenia	0.000	0.996	0.004
F25.9 Schizoaffective disorder, unspecified	0.000	0.996	0.004
R45.0 Nervousness	0.000	0.996	0.004
M35.7 Hypermobility syndrome	0.004	0.996	0.000
S01.9 Open wound of head, part unspecified	0.000	0.996	0.004
F28 Other nonorganic psychotic disorders	0.000	0.996	0.004
F24 Induced delusional disorder	0.000	0.996	0.004
F21 Schizotypal disorder	0.000	0.996	0.004
M35 Other systemic involvement of connective tissue	0.004	0.996	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.996	0.004
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.996	0.004
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.996	0.004
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.996	0.004
R45.6 Physical violence	0.000	0.996	0.004
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.996	0.004
M35.1 Other overlap syndromes	0.004	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.996	0.004
F22.9 Persistent delusional disorder, unspecified	0.000	0.996	0.004
R45.1 Restlessness and agitation	0.000	0.996	0.004
K55.0 Acute vascular disorders of intestine	0.000	0.996	0.004
Q21.3 Tetralogy of Fallot	0.000	0.996	0.004
I15.1 Hypertension secondary to other renal disorders	0.004	0.996	0.000
R45.4 Irritability and anger	0.000	0.996	0.004
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.996	0.004
I95.9 Hypotension, unspecified	0.000	0.996	0.004
Q27.4 Congenital phlebectasia	0.000	0.996	0.004
Q27.2 Other congenital malformations of renal artery	0.000	0.996	0.004
Q27.1 Congenital renal artery stenosis	0.000	0.996	0.004
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.996	0.004
S60.9 Superficial injury of wrist and hand, unspecified	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.000	0.996	0.004
F22.8 Other persistent delusional disorders	0.000	0.996	0.004
F25.8 Other schizoaffective disorders	0.000	0.996	0.004
R44.2 Other hallucinations	0.000	0.996	0.004
R44.3 Hallucinations, unspecified	0.000	0.996	0.004
R44.0 Auditory hallucinations	0.000	0.996	0.004
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.996	0.004
Q21.4 Aortopulmonary septal defect	0.000	0.996	0.004
Q21.2 Atrioventricular septal defect	0.000	0.996	0.004
Z57.2 Occupational exposure to dust	0.004	0.996	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.003	0.996	0.000
Z57.7 Occupational exposure to vibration	0.003	0.996	0.000
Z57.6 Occupational exposure to extreme temperature	0.003	0.996	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.003	0.996	0.000
Z57.1 Occupational exposure to radiation	0.003	0.996	0.000
Z57.0 Occupational exposure to noise	0.003	0.996	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.996	0.003
F25.2 Schizoaffective disorder, mixed type	0.000	0.996	0.003
F23.8 Other acute and transient psychotic disorders	0.000	0.996	0.003
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.996	0.003
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.996	0.003
S81.9 Open wound of lower leg, part unspecified	0.000	0.996	0.004
Z57.8 Occupational exposure to other risk-factors	0.003	0.997	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.000	0.997	0.003
M35.2 Behcet's disease	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.997	0.003
I15 Secondary hypertension	0.003	0.997	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.003	0.997	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.003	0.997	0.000
M35.5 Multifocal fibrosclerosis	0.003	0.997	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.003	0.997	0.000
I15.9 Seconday hypertension, unspecified	0.003	0.997	0.000
I15.0 Renovascular hypertension	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.997	0.003
Q26 Congenital malformations of great veins	0.000	0.997	0.003
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.997	0.003
M54.17 Radiculopathy (Lumbosacral region)	0.003	0.997	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.997	0.003
Q21.8 Other congenital malformations of cardiac septa	0.000	0.997	0.003
Q25 Congenital malformations of great arteries	0.000	0.997	0.003
M35.8 Other specified systemic involvement of connective tissue	0.003	0.997	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.997	0.003
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.997	0.003
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.997	0.003
Q28.1 Other malformations of precerebral vessels	0.000	0.997	0.003
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
C10.9 Oropharynx, unspecified	0.000	0.997	0.003
I15.8 Other secondary hypertension	0.003	0.997	0.000
M54.2 Cervicalgia	0.003	0.997	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.997	0.003
R41.3 Other amnesia	0.000	0.997	0.003
R43 Disturbances of smell and taste	0.000	0.997	0.003
R46 Symptoms and signs involving appearance and behaviour	0.000	0.997	0.003
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.997	0.003
Q22.5 Ebstein's anomaly	0.000	0.997	0.003
S81 Open wound of lower leg	0.000	0.997	0.003
K13.0 Diseases of lips	0.000	0.997	0.003
Q28.3 Other malformations of cerebral vessels	0.000	0.997	0.003
Q22.1 Congenital pulmonary valve stenosis	0.000	0.997	0.003
I15.2 Hypertension secondary to endocrine disorders	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.000	0.997	0.003
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.000	0.997	0.003
Q22.8 Other congenital malformations of tricuspid valve	0.000	0.997	0.003
Q22.6 Hypoplastic right heart syndrome	0.000	0.997	0.003
Q22.4 Congenital tricuspid stenosis	0.000	0.997	0.003
Q22.3 Other congenital malformations of pulmonary valve	0.000	0.997	0.003
Q22.2 Congenital pulmonary valve insufficiency	0.000	0.997	0.003
Q22.0 Pulmonary valve atresia	0.000	0.997	0.003
Q23.0 Congenital stenosis of aortic valve	0.000	0.997	0.003
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.997	0.003
Q25.3 Stenosis of aorta	0.000	0.997	0.003
Q25.6 Stenosis of pulmonary artery	0.000	0.997	0.003
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.002	0.997	0.000
D32.0 Cerebral meninges	0.000	0.997	0.003
R43.8 Other and unspecified disturbances of smell and taste	0.000	0.997	0.003
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.000	0.997	0.002
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.000	0.997	0.002
Q20.6 Isomerism of atrial appendages	0.000	0.997	0.002
Q20.5 Discordant atrioventricular connexion	0.000	0.997	0.002
Q20.4 Double inlet ventricle	0.000	0.997	0.002
Q20.3 Discordant ventriculoarterial connexion	0.000	0.997	0.002
Q20.2 Double outlet left ventricle	0.000	0.997	0.002
Q20.1 Double outlet right ventricle	0.000	0.997	0.002
Q20.0 Common arterial trunk	0.000	0.997	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.997	0.002
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.997	0.002
Q23.4 Hypoplastic left heart syndrome	0.000	0.997	0.002
Q23.3 Congenital mitral insufficiency	0.000	0.997	0.002
Q23.2 Congenital mitral stenosis	0.000	0.997	0.002
Q26.9 Congenital malformation of great vein, unspecified	0.000	0.997	0.002
Q26.8 Other congenital malformations of great veins	0.000	0.997	0.002
Q26.6 Portal vein-hepatic artery fistula	0.000	0.997	0.002
Q26.5 Anomalous portal venous connexion	0.000	0.997	0.002
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.000	0.997	0.002
Q26.3 Partial anomalous pulmonary venous connexion	0.000	0.997	0.002
Q26.2 Total anomalous pulmonary venous connexion	0.000	0.997	0.002
Q26.1 Persistent left superior vena cava	0.000	0.997	0.002
Q26.0 Congenital stenosis of vena cava	0.000	0.997	0.002
S81.0 Open wound of knee	0.000	0.997	0.003
R46.4 Slowness and poor responsiveness	0.000	0.997	0.002
Q25.9 Congenital malformation of great arteries, unspecified	0.000	0.997	0.002
Q25.8 Other congenital malformations of great arteries	0.000	0.997	0.002
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.997	0.002
Q25.5 Atresia of pulmonary artery	0.000	0.997	0.002
Q25.2 Atresia of aorta	0.000	0.997	0.002
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
Q23.1 Congenital insufficiency of aortic valve	0.000	0.997	0.002
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
Q25.1 Coarctation of aorta	0.000	0.998	0.002
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
M54.27 Cervicalgia-Lumbosacral	0.002	0.998	0.000
M54.26 Cervicalgia-Lumbar	0.002	0.998	0.000
M54.25 Cervicalgia-Thoracolumbar	0.002	0.998	0.000
M54.24 Cervicalgia-Thoracic	0.002	0.998	0.000
M54.20 Cervicalgia-Mult site	0.002	0.998	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.998	0.002
R46.0 Very low level of personal hygiene	0.000	0.998	0.002
M54.1 Radiculopathy	0.002	0.998	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
R41.2 Retrograde amnesia	0.000	0.998	0.002
D75.1 Secondary polycythaemia	0.000	0.998	0.002
Q25.0 Patent ductus arteriosus	0.000	0.998	0.002
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.000	0.998	0.002
R46.6 Undue concern and preoccupation with stressful events	0.000	0.998	0.002
R46.5 Suspiciousness and marked evasiveness	0.000	0.998	0.002
R46.3 Overactivity	0.000	0.998	0.002
R46.1 Bizarre personal appearance	0.000	0.998	0.002
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
D37.7 Other digestive organs	0.000	0.998	0.002
M54.23 Cervicalgia (Cervicothoracic region)	0.002	0.998	0.000
R41.1 Anterograde amnesia	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.000	0.998	0.002
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
R43.2 Parageusia	0.000	0.998	0.002
M54.28 Cervicalgia-Sacral/sacrococ	0.002	0.998	0.000
R43.1 Parosmia	0.000	0.998	0.002
R43.0 Anosmia	0.000	0.998	0.002
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.998	0.002
H05.8 Other disorders of orbit	0.002	0.998	0.000
R46.2 Strange and inexplicable behaviour	0.000	0.998	0.002
M54.14 Radiculopathy (Thoracic region)	0.002	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
J01.9 Acute sinusitis, unspecified	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.000	0.998	0.002
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.998	0.002
B17.1 Acute hepatitis C	0.000	0.998	0.002
N64.8 Other specified disorders of breast	0.002	0.998	0.000
K61.3 Ischiorectal abscess	0.000	0.998	0.002
M95.0 Acquired deformity of nose	0.002	0.998	0.000
K13 Other diseases of lip and oral mucosa	0.000	0.998	0.002
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
M54.15 Radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.002	0.998	0.000
K22.4 Dyskinesia of oesophagus	0.000	0.998	0.002
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.002
Q24.3 Pulmonary infundibular stenosis	0.000	0.998	0.002
Q24.2 Cor triatriatum	0.000	0.998	0.002
Q24.1 Levocardia	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
K31.8 Other specified diseases of stomach and duodenum	0.000	0.998	0.002
M19.27 Other secondary arthrosis (Ankle and foot)	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
Q24.0 Dextrocardia	0.000	0.998	0.002
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.998	0.002
M54.9 Dorsalgia, unspecified	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.002
M54 Dorsalgia	0.002	0.998	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.002	0.998	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.000	0.998	0.002
K13.1 Cheek and lip biting	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.000	0.998	0.002
M54.29 Cervicalgia-Site unspe	0.002	0.998	0.000
M54.86 Other dorsalgia (Lumbar region)	0.002	0.998	0.000
Q24.6 Congenital heart block	0.000	0.998	0.002
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.002	0.998	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.998	0.002
M54.6 Pain in thoracic spine	0.002	0.998	0.000
R41.0 Disorientation, unspecified	0.000	0.998	0.002
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.000	0.998	0.002
K13.3 Hairy leukoplakia	0.000	0.998	0.002
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
M54.19 Radiculopathy (Site unspecified)	0.002	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.002	0.998	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.002	0.998	0.000
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
M19.2 Other secondary arthrosis	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.001	0.998	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.002	0.998	0.000
K13.5 Oral submucous fibrosis	0.000	0.998	0.001
M54.8 Other dorsalgia	0.002	0.998	0.000
M54.0 Panniculitis affecting regions of neck and back	0.001	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.002	0.998	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
M54.12 Radiculopathy (Cervical region)	0.002	0.998	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.002	0.998	0.000
X41.9 Unspecified place	0.000	0.998	0.002
C10 Malignant neoplasm of oropharynx	0.000	0.998	0.002
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
H40.8 Other glaucoma	0.000	0.998	0.002
M54.3 Sciatica	0.002	0.998	0.000
T17.2 Foreign body in pharynx	0.000	0.998	0.002
Z44.3 Fitting and adjustment of external breast prosthesis	0.002	0.998	0.000
M54.69 Pain in thoracic spine-Site unspe	0.001	0.998	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.001	0.998	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.001	0.998	0.000
M54.66 Pain in thoracic spine-Lumbar	0.001	0.998	0.000
M54.62 Pain in thoracic spine-Cervical	0.001	0.998	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.001	0.998	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.001	0.998	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.000	0.998	0.001
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.998	0.000
C41.1 Mandible	0.000	0.998	0.001
Q24.8 Other specified congenital malformations of heart	0.000	0.998	0.001
S60.0 Contusion of finger(s) without damage to nail	0.001	0.998	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.001	0.998	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.001	0.998	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.998	0.000
G25.3 Myoclonus	0.000	0.998	0.002
M54.84 Other dorsalgia (Thoracic region)	0.001	0.998	0.000
M19 Other arthrosis	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.999	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.001	0.999	0.000
M19.28 Other secondary arthrosis (Other)	0.001	0.999	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.001	0.999	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.001	0.999	0.000
M19.24 Other secondary arthrosis (Hand)	0.001	0.999	0.000
M19.23 Other secondary arthrosis (Forearm)	0.001	0.999	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.001	0.999	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.001	0.999	0.000
M70.22 Olecranon bursitis-Upper arm	0.001	0.999	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.001	0.999	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.001	0.999	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.001	0.999	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.001	0.999	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.001	0.999	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.001	0.999	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.001	0.999	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.001	0.999	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.001	0.999	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.001	0.999	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.001	0.999	0.000
M54.82 Other dorsalgia (Cervical region)	0.001	0.999	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.001	0.999	0.000
H34.2 Other retinal artery occlusions	0.000	0.999	0.001
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.999	0.001
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.001	0.999	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.001	0.999	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.001	0.999	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.999	0.001
M54.35 Sciatica (Thoracolumbar region)	0.001	0.999	0.000
M54.34 Sciatica-Thoracic	0.001	0.999	0.000
M54.33 Sciatica-Cervicothoracic	0.001	0.999	0.000
M54.32 Sciatica-Cervical	0.001	0.999	0.000
M54.31 Sciatica-Occipit-atl-axl	0.001	0.999	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.999	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
C10.8 Overlapping lesion of oropharynx	0.000	0.999	0.001
C10.4 Branchial cleft	0.000	0.999	0.001
C10.3 Posterior wall of oropharynx	0.000	0.999	0.001
C10.2 Lateral wall of oropharynx	0.000	0.999	0.001
C10.1 Anterior surface of epiglottis	0.000	0.999	0.001
C10.0 Vallecula	0.000	0.999	0.001
I60.8 Other subarachnoid haemorrhage	0.000	0.999	0.001
Q89.2 Congenital malformations of other endocrine glands	0.001	0.999	0.000
W19.3 Sports and athletics area	0.000	0.999	0.001
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.001	0.999	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.001	0.999	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.001	0.999	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.999	0.001
M19.21 Other secondary arthrosis (Shoulder region)	0.001	0.999	0.000
M54.30 Sciatica (Multiple sites in spine)	0.001	0.999	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.999	0.001
M19.8 Other specified arthrosis	0.001	0.999	0.000
S60 Superficial injury of wrist and hand	0.001	0.999	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.001	0.999	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.999	0.001
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.999	0.001
E24.9 Cushing's syndrome, unspecified	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.001	0.999	0.000
H66.9 Otitis media, unspecified	0.001	0.999	0.000
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.001	0.999	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
M89.84 Other specified disorders of bone (Hand)	0.001	0.999	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
E13.9 Without complications	0.000	0.999	0.001
M19.84 Other specified arthrosis (Hand)	0.001	0.999	0.000
C41.9 Bone and articular cartilage, unspecified	0.000	0.999	0.001
G91.0 Communicating hydrocephalus	0.000	0.999	0.001
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.001	0.999	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.999	0.001
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.000	0.999	0.001
M24.27 Disorder of ligament (Ankle and foot)	0.001	0.999	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.001	0.999	0.000
H60.3 Other infective otitis externa	0.001	0.999	0.000
I74.5 Embolism and thrombosis of iliac artery	0.001	0.999	0.000
J01.1 Acute frontal sinusitis	0.001	0.999	0.000
M89.8 Other specified disorders of bone	0.001	0.999	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.001	0.999	0.000
M19.88 Other specified arthrosis (Other)	0.001	0.999	0.000
M19.86 Other specified arthrosis (Lower leg)	0.001	0.999	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.001	0.999	0.000
M19.83 Other specified arthrosis (Forearm)	0.001	0.999	0.000
M19.82 Other specified arthrosis (Upper arm)	0.001	0.999	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.001	0.999	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.001	0.999	0.000
A49.1 Streptococcal infection, unspecified	0.001	0.999	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.999	0.001
J35.0 Chronic tonsillitis	0.000	0.999	0.001
Q83.8 Other congenital malformations of breast	0.001	0.999	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.999	0.001
J01 Acute sinusitis	0.001	0.999	0.000
T17.3 Foreign body in larynx	0.000	0.999	0.001
T18.5 Foreign body in anus and rectum	0.001	0.999	0.000
T18.1 Foreign body in oesophagus	0.001	0.999	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.999	0.000
Q89 Other congenital malformations, not elsewhere classified	0.001	0.999	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.999	0.001
K61.1 Rectal abscess	0.000	0.999	0.001
M54.94 Dorsalgia, unspecified (Thoracic region)	0.001	0.999	0.000
M89.88 Other specified disorders of bone (Other)	0.001	0.999	0.000
M54.4 Lumbago with sciatica	0.001	0.999	0.000
O90.9 Complication of the puerperium, unspecified	0.001	0.999	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.001	0.999	0.000
T18.0 Foreign body in mouth	0.001	0.999	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
M19.87 Other specified arthrosis (Ankle and foot)	0.001	0.999	0.000
M43.06 Spondylolysis (Lumbar region)	0.001	0.999	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.001	0.999	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.001	0.999	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.000	0.999	0.001
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.000	0.999	0.001
D75 Other diseases of blood and blood-forming organs	0.000	0.999	0.001
Q82 Other congenital malformations of skin	0.001	0.999	0.000
M54.39 Sciatica (Site unspecified)	0.001	0.999	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.001	0.999	0.000
C15.9 Oesophagus, unspecified	0.001	0.999	0.000
C41.0 Bones of skull and face	0.000	0.999	0.001
G63.2 Diabetic polyneuropathy	0.001	0.999	0.000
J01.8 Other acute sinusitis	0.001	0.999	0.000
J01.3 Acute sphenoidal sinusitis	0.001	0.999	0.000
J01.0 Acute maxillary sinusitis	0.001	0.999	0.000
M95.2 Other acquired deformity of head	0.001	0.999	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.001	0.999	0.000
Q63.0 Accessory kidney	0.001	0.999	0.000
Q89.3 Situs inversus	0.001	0.999	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.999	0.001
M54.89 Other dorsalgia (Site unspecified)	0.001	0.999	0.000
C41.4 Pelvic bones, sacrum and coccyx	0.000	0.999	0.001
K62.9 Disease of anus and rectum, unspecified	0.001	0.999	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.999	0.000
Q89.8 Other specified congenital malformations	0.001	0.999	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.999	0.000
Q89.4 Conjoined twins	0.001	0.999	0.000
Q89.1 Congenital malformations of adrenal gland	0.001	0.999	0.000
Q89.0 Congenital malformations of spleen	0.001	0.999	0.000
S60.2 Contusion of other parts of wrist and hand	0.001	0.999	0.000
B17 Other acute viral hepatitis	0.000	0.999	0.001
T17 Foreign body in respiratory tract	0.000	0.999	0.001
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.999	0.001
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.001	0.999	0.000
M54.44 Lumbago with sciatica-Thoracic	0.001	0.999	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.001	0.999	0.000
M54.42 Lumbago with sciatica-Cervical	0.001	0.999	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.001	0.999	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.001	0.999	0.000
S72.30 Fracture of shaft of femur (closed)	0.001	0.999	0.000
B17.8 Other specified acute viral hepatitis	0.000	0.999	0.001
F15.1 Harmful use	0.001	0.999	0.000
J01.4 Acute pansinusitis	0.001	0.999	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.999	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.001	0.999	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.999	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.999	0.000
Q82.3 Incontinentia pigmenti	0.001	0.999	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.999	0.000
Q85.1 Tuberous sclerosis	0.001	0.999	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.001	0.999	0.000
C41.8 Overlapping lesion of bone and articular cartilage	0.000	0.999	0.001
C41.2 Vertebral column	0.000	0.999	0.001
J01.2 Acute ethmoidal sinusitis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations