TreeWAS – Variant ID: rs10773002

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M17.9 Gonarthrosis, unspecified	0.914	0.086	0.000
M17 Gonarthrosis [arthrosis of knee]	0.895	0.105	0.000
M17.0 Primary gonarthrosis, bilateral	0.888	0.112	0.000
M17.1 Other primary gonarthrosis	0.854	0.146	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.581	0.419	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.560	0.440	0.000
M17.3 Other posttraumatic gonarthrosis	0.544	0.455	0.000
M17.5 Other secondary gonarthrosis	0.477	0.523	0.000
D25.9 Leiomyoma of uterus, unspecified	0.091	0.909	0.000
M15-M19 Arthrosis	0.086	0.914	0.000
M19 Other arthrosis	0.064	0.936	0.000
M19.0 Primary arthrosis of other joints	0.063	0.937	0.000
M15 Polyarthrosis	0.062	0.938	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.062	0.938	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.052	0.948	0.000
M15.8 Other polyarthrosis	0.051	0.949	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.049	0.951	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.048	0.952	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.048	0.952	0.000
M19.08 Primary arthrosis of other joints (Other)	0.047	0.952	0.000
M15.4 Erosive (osteo)arthrosis	0.047	0.953	0.000
M19.8 Other specified arthrosis	0.046	0.954	0.000
M15.1 Heberden's nodes (with arthropathy)	0.046	0.954	0.000
M15.0 Primary generalised (osteo)arthrosis	0.045	0.955	0.000
M19.2 Other secondary arthrosis	0.045	0.955	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.045	0.955	0.000
M15.9 Polyarthrosis, unspecified	0.042	0.958	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.042	0.958	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.041	0.959	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.040	0.960	0.000
M15.3 Secondary multiple arthrosis	0.039	0.961	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.036	0.964	0.000
M18 Arthrosis of first carpometacarpal joint	0.035	0.965	0.000
M19.84 Other specified arthrosis (Hand)	0.035	0.965	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.034	0.966	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.033	0.967	0.000
M19.88 Other specified arthrosis (Other)	0.033	0.967	0.000
M19.86 Other specified arthrosis (Lower leg)	0.033	0.967	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.033	0.967	0.000
M19.83 Other specified arthrosis (Forearm)	0.033	0.967	0.000
M19.82 Other specified arthrosis (Upper arm)	0.033	0.967	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.033	0.967	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.033	0.967	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.032	0.967	0.000
M19.28 Other secondary arthrosis (Other)	0.032	0.967	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.032	0.967	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.032	0.967	0.000
M19.24 Other secondary arthrosis (Hand)	0.032	0.967	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.032	0.967	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.032	0.967	0.000
L03.2 Cellulitis of face	0.000	0.967	0.033
M19.23 Other secondary arthrosis (Forearm)	0.032	0.968	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.031	0.969	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.030	0.970	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.028	0.972	0.000
M15.99 Polyosteoarthritis, unspecified	0.027	0.972	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.027	0.973	0.000
M19.1 Posttraumatic arthrosis of other joints	0.026	0.973	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.025	0.975	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.025	0.975	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.025	0.975	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.025	0.975	0.000
F31 Bipolar affective disorder	0.000	0.977	0.023
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.978	0.022
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.021	0.979	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.980	0.020
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.980	0.020
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.980	0.020
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.980	0.020
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.980	0.020
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.019	0.981	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.019	0.981	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.019	0.981	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.019	0.981	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.019	0.981	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.018	0.982	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.982	0.018
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.017	0.982	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.016	0.984	0.000
F31.8 Other bipolar affective disorders	0.000	0.984	0.016
F30-F39 Mood [affective] disorders	0.000	0.984	0.016
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.015	0.985	0.000
F34 Persistent mood [affective] disorders	0.000	0.985	0.015
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.985	0.015
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.014	0.986	0.000
F34.1 Dysthymia	0.000	0.986	0.014
F33 Recurrent depressive disorder	0.000	0.986	0.014
F30 Manic episode	0.000	0.987	0.013
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.987	0.013
F31.7 Bipolar affective disorder, currently in remission	0.000	0.987	0.013
F38 Other mood [affective] disorders	0.000	0.987	0.013
F34.0 Cyclothymia	0.000	0.988	0.012
F39 Unspecified mood [affective] disorder	0.000	0.988	0.012
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.988	0.012
F30.0 Hypomania	0.000	0.988	0.012
F33.8 Other recurrent depressive disorders	0.000	0.989	0.011
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.989	0.011
F34.8 Other persistent mood [affective] disorders	0.000	0.989	0.011
F30.2 Mania with psychotic symptoms	0.000	0.989	0.011
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.011	0.989	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.989	0.011
I26 Pulmonary embolism	0.011	0.989	0.000
F38.8 Other specified mood [affective] disorders	0.000	0.990	0.010
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.990	0.010
F30.8 Other manic episodes	0.000	0.990	0.010
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.009	0.990	0.000
F38.1 Other recurrent mood [affective] disorders	0.000	0.991	0.009
F30.1 Mania without psychotic symptoms	0.000	0.991	0.009
F38.0 Other single mood [affective] disorders	0.000	0.991	0.009
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.991	0.009
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.991	0.009
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.009	0.991	0.000
F30.9 Manic episode, unspecified	0.000	0.992	0.008
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.992	0.008
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.007	0.993	0.000
M19.9 Arthrosis, unspecified	0.007	0.993	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.007	0.993	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.993	0.007
M19.98 Arthrosis, unspecified (Other)	0.007	0.993	0.000
C34.3 Lower lobe, bronchus or lung	0.007	0.993	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.993	0.007
V18.3 Person injured while boarding or alighting	0.000	0.993	0.007
K83.0 Cholangitis	0.000	0.993	0.007
V18.9 Unspecified pedal cyclist injured in traffic accident	0.000	0.993	0.007
V18.4 Driver injured in traffic accident	0.000	0.993	0.007
V18.5 Passenger injured in traffic accident	0.000	0.993	0.006
C50.1 Central portion of breast	0.000	0.993	0.007
M19.94 Arthrosis, unspecified (Hand)	0.006	0.994	0.000
V18.1 Passenger injured in nontraffic accident	0.000	0.994	0.006
M19.90 Arthrosis, unspecified (Multiple sites)	0.006	0.994	0.000
M31.6 Other giant cell arteritis	0.000	0.994	0.006
C34.9 Bronchus or lung, unspecified	0.006	0.994	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.006	0.994	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.006	0.994	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.995	0.005
C34 Malignant neoplasm of bronchus and lung	0.005	0.995	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.000	0.995	0.005
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.000	0.995	0.005
E03.9 Hypothyroidism, unspecified	0.000	0.995	0.005
D25 Leiomyoma of uterus	0.005	0.995	0.000
A46 Erysipelas	0.000	0.995	0.005
C34.1 Upper lobe, bronchus or lung	0.005	0.995	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.005	0.995	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.004	0.996	0.000
C34.0 Main bronchus	0.004	0.996	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.004	0.996	0.000
F32 Depressive episode	0.000	0.996	0.004
C34.8 Overlapping lesion of bronchus and lung	0.004	0.996	0.000
E16.2 Hypoglycaemia, unspecified	0.004	0.996	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.004	0.996	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.996	0.004
M19.92 Arthrosis, unspecified (Upper arm)	0.004	0.996	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.004	0.996	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.004	0.996	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.996	0.004
K83 Other diseases of biliary tract	0.000	0.996	0.004
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
A09.9 Gastroenteritis and colitis of unspecified origin	0.004	0.996	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.004	0.996	0.000
K83.9 Disease of biliary tract, unspecified	0.000	0.997	0.003
T42.4 Benzodiazepines	0.003	0.997	0.000
E11.9 Without complications	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
C50.3 Lower-inner quadrant of breast	0.000	0.997	0.003
F32.8 Other depressive episodes	0.000	0.997	0.003
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.997	0.003
A49.8 Other bacterial infections of unspecified site	0.000	0.997	0.003
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.003	0.997	0.000
K83.3 Fistula of bile duct	0.000	0.997	0.003
A39.0 Meningococcal meningitis	0.000	0.997	0.003
E16.1 Other hypoglycaemia	0.003	0.997	0.000
K83.5 Biliary cyst	0.000	0.997	0.003
M19.91 Arthrosis, unspecified (Shoulder region)	0.003	0.997	0.000
E16 Other disorders of pancreatic internal secretion	0.003	0.997	0.000
K83.2 Perforation of bile duct	0.000	0.997	0.003
C50 Malignant neoplasm of breast	0.000	0.997	0.003
I15.1 Hypertension secondary to other renal disorders	0.003	0.997	0.000
K83.4 Spasm of sphincter of Oddi	0.000	0.997	0.003
A49 Bacterial infection of unspecified site	0.000	0.997	0.003
A30-A49 Other bacterial diseases	0.000	0.997	0.003
C50.4 Upper-outer quadrant of breast	0.000	0.997	0.003
C44.6 Skin of upper limb, including shoulder	0.003	0.997	0.000
C34.2 Middle lobe, bronchus or lung	0.001	0.997	0.002
T42.1 Iminostilbenes	0.003	0.997	0.000
A39 Meningococcal infection	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.003	0.997	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.997	0.003
A40.8 Other streptococcal septicaemia	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.997	0.003
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.997	0.000
N45 Orchitis and epididymitis	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
D25.2 Subserosal leiomyoma of uterus	0.003	0.997	0.000
T42.3 Barbiturates	0.002	0.997	0.000
Z32.1 Pregnancy confirmed	0.000	0.997	0.003
A40 Streptococcal septicaemia	0.000	0.997	0.003
I12.0 Hypertensive renal disease with renal failure	0.003	0.997	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.997	0.000
G47.3 Sleep apnoea	0.003	0.997	0.000
Z49.0 Preparatory care for dialysis	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
I28 Other diseases of pulmonary vessels	0.002	0.997	0.000
A49.9 Bacterial infection, unspecified	0.000	0.997	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.002	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.002	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.002	0.998	0.000
E16.3 Increased secretion of glucagon	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
A42 Actinomycosis	0.000	0.998	0.002
C50.9 Breast, unspecified	0.000	0.998	0.002
R22.0 Localised swelling, mass and lump, head	0.000	0.998	0.002
A49.3 Mycoplasma infection, unspecified	0.000	0.998	0.002
C50.6 Axillary tail of breast	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
A44 Bartonellosis	0.000	0.998	0.002
A43 Nocardiosis	0.000	0.998	0.002
A37 Whooping cough	0.000	0.998	0.002
A36 Diphtheria	0.000	0.998	0.002
A32 Listeriosis	0.000	0.998	0.002
A30 Leprosy [Hansen's disease]	0.000	0.998	0.002
A38 Scarlet fever	0.000	0.998	0.002
A35 Other tetanus	0.000	0.998	0.002
A34 Obstetrical tetanus	0.000	0.998	0.002
A33 Tetanus neonatorum	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
F32.0 Mild depressive episode	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
A39.9 Meningococcal infection, unspecified	0.000	0.998	0.002
A39.8 Other meningococcal infections	0.000	0.998	0.002
A39.5 Meningococcal heart disease	0.000	0.998	0.002
A39.3 Chronic meningococcaemia	0.000	0.998	0.002
A39.2 Acute meningococcaemia	0.000	0.998	0.002
A39.1 Waterhouse-Friderichsen syndrome	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
A31 Infection due to other mycobacteria	0.000	0.998	0.002
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
R68.8 Other specified general symptoms and signs	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
A48 Other bacterial diseases, not elsewhere classified	0.000	0.998	0.002
M43.1 Spondylolisthesis	0.002	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
A39.4 Meningococcaemia, unspecified	0.000	0.998	0.002
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.998	0.002
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.998	0.002
R25.8 Other and unspecified abnormal involuntary movements	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
A42.9 Actinomycosis, unspecified	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.002	0.998	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.002	0.998	0.000
A40.2 Septicaemia due to streptococcus, group D	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.998	0.000
I28.1 Aneurysm of pulmonary artery	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.000	0.998	0.002
A42.7 Actinomycotic septicaemia	0.000	0.998	0.002
A42.2 Cervicofacial actinomycosis	0.000	0.998	0.002
A42.1 Abdominal actinomycosis	0.000	0.998	0.002
A42.0 Pulmonary actinomycosis	0.000	0.998	0.002
G96.0 Cerebrospinal fluid leak	0.000	0.998	0.002
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.002	0.998	0.000
A40.9 Streptococcal septicaemia, unspecified	0.000	0.998	0.002
A40.0 Septicaemia due to streptococcus, group A	0.000	0.998	0.002
A30.9 Leprosy, unspecified	0.000	0.998	0.002
A30.8 Other forms of leprosy	0.000	0.998	0.002
A30.5 Lepromatous leprosy	0.000	0.998	0.002
A30.4 Borderline lepromatous leprosy	0.000	0.998	0.002
A30.3 Borderline leprosy	0.000	0.998	0.002
A30.2 Borderline tuberculoid leprosy	0.000	0.998	0.002
A30.1 Tuberculoid leprosy	0.000	0.998	0.002
A30.0 Indeterminate leprosy	0.000	0.998	0.002
A32.9 Listeriosis, unspecified	0.000	0.998	0.002
A32.8 Other forms of listeriosis	0.000	0.998	0.002
A32.7 Listerial septicaemia	0.000	0.998	0.002
A32.1 Listerial meningitis and meningoencephalitis	0.000	0.998	0.002
A32.0 Cutaneous listeriosis	0.000	0.998	0.002
A36.9 Diphtheria, unspecified	0.000	0.998	0.002
A36.8 Other diphtheria	0.000	0.998	0.002
A36.3 Cutaneous diphtheria	0.000	0.998	0.002
A36.2 Laryngeal diphtheria	0.000	0.998	0.002
A36.1 Nasopharyngeal diphtheria	0.000	0.998	0.002
A36.0 Pharyngeal diphtheria	0.000	0.998	0.002
A37.9 Whooping cough, unspecified	0.000	0.998	0.002
A37.8 Whooping cough due to other Bordetella species	0.000	0.998	0.002
A37.1 Whooping cough due to Bordetella parapertussis	0.000	0.998	0.002
A37.0 Whooping cough due to Bordetella pertussis	0.000	0.998	0.002
A43.9 Nocardiosis, unspecified	0.000	0.998	0.002
A43.8 Other forms of nocardiosis	0.000	0.998	0.002
A43.1 Cutaneous nocardiosis	0.000	0.998	0.002
A43.0 Pulmonary nocardiosis	0.000	0.998	0.002
A44.9 Bartonellosis, unspecified	0.000	0.998	0.002
A44.8 Other forms of bartonellosis	0.000	0.998	0.002
A44.1 Cutaneous and mucocutaneous bartonellosis	0.000	0.998	0.002
A44.0 Systemic bartonellosis	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
M43.12 Spondylolisthesis (Cervical region)	0.002	0.998	0.000
C50.0 Nipple and areola	0.000	0.998	0.002
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.002	0.998	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.002	0.998	0.000
K90.0 Coeliac disease	0.002	0.998	0.000
G47 Sleep disorders	0.002	0.998	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
G35 Multiple sclerosis	0.000	0.998	0.002
A48.8 Other specified bacterial diseases	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
A31.1 Cutaneous mycobacterial infection	0.000	0.998	0.002
A42.8 Other forms of actinomycosis	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.002	0.998	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.998	0.002
M43.19 Spondylolisthesis (Site unspecified)	0.002	0.998	0.000
A31.8 Other mycobacterial infections	0.000	0.998	0.002
H25.9 Senile cataract, unspecified	0.000	0.998	0.002
I28.9 Disease of pulmonary vessels, unspecified	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
A31.0 Pulmonary mycobacterial infection	0.000	0.998	0.002
A48.4 Brazilian purpuric fever	0.000	0.998	0.002
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.000	0.998	0.002
A48.0 Gas gangrene	0.000	0.998	0.002
Z49.2 Other dialysis	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
A40.1 Septicaemia due to streptococcus, group B	0.000	0.998	0.002
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.002	0.998	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.002	0.998	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.002	0.998	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
I63.9 Cerebral infarction, unspecified	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
A31.9 Mycobacterial infection, unspecified	0.000	0.998	0.002
C50.5 Lower-outer quadrant of breast	0.000	0.998	0.002
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.002	0.998	0.000
A48.3 Toxic shock syndrome	0.000	0.998	0.002
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.002	0.998	0.000
G47.4 Narcolepsy and cataplexy	0.002	0.998	0.000
K83.1 Obstruction of bile duct	0.000	0.998	0.002
M31.0 Hypersensitivity angiitis	0.000	0.998	0.002
M75.4 Impingement syndrome of shoulder	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
A48.1 Legionnaires' disease	0.000	0.998	0.002
N85.0 Endometrial glandular hyperplasia	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
R22.1 Localised swelling, mass and lump, neck	0.000	0.998	0.002
M31 Other necrotising vasculopathies	0.000	0.998	0.002
G47.8 Other sleep disorders	0.002	0.998	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.998	0.002
Z73.6 Limitation of activities due to disability	0.002	0.998	0.000
M54.29 Cervicalgia-Site unspe	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
R09.0 Asphyxia	0.000	0.998	0.002
I27.8 Other specified pulmonary heart diseases	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
F99 Mental disorder, not otherwise specified	0.000	0.998	0.002
I12 Hypertensive renal disease	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.002	0.998	0.000
K11.6 Mucocele of salivary gland	0.000	0.998	0.002
D27 Benign neoplasm of ovary	0.000	0.998	0.002
V10-V19 Pedal cyclist injured in transport accident	0.000	0.998	0.002
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
T38.7 Androgens and anabolic congeners	0.001	0.998	0.000
T38.4 Oral contraceptives	0.001	0.998	0.000
T38.2 Antithyroid drugs	0.001	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.001	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
N76.3 Subacute and chronic vulvitis	0.000	0.998	0.002
G47.2 Disorders of the sleep-wake schedule	0.002	0.998	0.000
M23.3 Other meniscus derangements	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
L65.9 Nonscarring hair loss, unspecified	0.000	0.998	0.002
M31.9 Necrotising vasculopathy, unspecified	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
A49.1 Streptococcal infection, unspecified	0.000	0.998	0.001
F32.1 Moderate depressive episode	0.000	0.998	0.001
H53.0 Amblyopia ex anopsia	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.001	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.001	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.001	0.998	0.000
Z73.5 Social role conflict, not elsewhere classified	0.001	0.998	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.001	0.998	0.000
Z73.2 Lack of relaxation and leisure	0.001	0.998	0.000
Z73.1 Accentuation of personality traits	0.001	0.998	0.000
Z73.0 Burn-out	0.001	0.998	0.000
I08 Multiple valve diseases	0.000	0.998	0.002
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
Z49 Care involving dialysis	0.002	0.998	0.000
H73.0 Acute myringitis	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations