TreeWAS – Variant ID: rs10793273

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.981	0.019
M84.0 Malunion of fracture	0.013	0.987	0.000
M84.03 Malunion of fracture (Forearm)	0.012	0.988	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.012	0.988	0.000
K86.1 Other chronic pancreatitis	0.000	0.988	0.012
M79.62 Pain in limb (Upper arm)	0.000	0.989	0.011
M84.48 Pathological fracture, not elsewhere classified (Other)	0.011	0.989	0.000
M79.63 Pain in limb (Forearm)	0.000	0.989	0.011
M79.67 Pain in limb (Ankle and foot)	0.000	0.989	0.011
K86 Other diseases of pancreas	0.000	0.989	0.011
M84.01 Malunion of fracture (Shoulder region)	0.011	0.989	0.000
M79.6 Pain in limb	0.000	0.989	0.011
M84.08 Malunion of fracture (Other)	0.010	0.989	0.000
M84.4 Pathological fracture, not elsewhere classified	0.011	0.989	0.000
M84.06 Malunion of fracture (Lower leg)	0.010	0.990	0.000
M84 Disorders of continuity of bone	0.010	0.990	0.000
K86.2 Cyst of pancreas	0.000	0.990	0.010
M84.8 Other disorders of continuity of bone	0.010	0.990	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.990	0.010
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.010	0.990	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.990	0.009
M84.09 Malunion of fracture (Site unspecified)	0.009	0.991	0.000
M84.00 Malunion of fracture (Multiple sites)	0.009	0.991	0.000
K86.8 Other specified diseases of pancreas	0.000	0.991	0.009
L89.1 Stage II decubitus ulcer	0.009	0.991	0.000
M79.60 Pain in limb (Multiple sites)	0.000	0.991	0.009
M84.02 Malunion of fracture (Upper arm)	0.009	0.991	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.008	0.991	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.008	0.992	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.008	0.992	0.000
M79.68 Pain in limb (Other)	0.000	0.992	0.008
M79.69 Pain in limb (Site unspecified)	0.000	0.992	0.008
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.008	0.992	0.000
Z63.4 Disappearance and death of family member	0.000	0.992	0.008
K86.3 Pseudocyst of pancreas	0.000	0.992	0.008
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.008	0.992	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.008	0.992	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.008	0.992	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.008	0.992	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.008	0.992	0.000
M84.9 Disorder of continuity of bone, unspecified	0.008	0.992	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.008	0.992	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.007	0.992	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.007	0.993	0.000
M84.88 Other disorders of continuity of bone (Other)	0.007	0.993	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.007	0.993	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.007	0.993	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.007	0.993	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.007	0.993	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.007	0.993	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.007	0.993	0.000
M79.61 Pain in limb (Shoulder region)	0.000	0.993	0.007
M84.04 Malunion of fracture (Hand)	0.007	0.993	0.000
M79.66 Pain in limb (Lower leg)	0.000	0.993	0.007
M84.2 Delayed union of fracture	0.007	0.993	0.000
Y86 Sequelae of other accidents	0.000	0.993	0.007
M84.3 Stress fracture, not elsewhere classified	0.007	0.993	0.000
H57.1 Ocular pain	0.007	0.993	0.000
M54.12 Radiculopathy (Cervical region)	0.007	0.993	0.000
N60.8 Other benign mammary dysplasias	0.006	0.994	0.000
Z63.7 Other stressful life events affecting family and household	0.000	0.994	0.006
H57 Other disorders of eye and adnexa	0.006	0.994	0.000
H57.8 Other specified disorders of eye and adnexa	0.006	0.994	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.006	0.994	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.006	0.994	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.006	0.994	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.006	0.994	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.006	0.994	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.006	0.994	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.006	0.994	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.006	0.994	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.006	0.994	0.000
M79.64 Pain in limb (Hand)	0.000	0.994	0.006
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.994	0.006
Z63 Other problems related to primary support group, including family circumstances	0.000	0.994	0.006
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.995	0.005
M84.29 Delayed union of fracture (Site unspecified)	0.005	0.995	0.000
M84.28 Delayed union of fracture (Other)	0.005	0.995	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.005	0.995	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.005	0.995	0.000
M84.24 Delayed union of fracture (Hand)	0.005	0.995	0.000
M84.23 Delayed union of fracture (Forearm)	0.005	0.995	0.000
M84.22 Delayed union of fracture (Upper arm)	0.005	0.995	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.005	0.995	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.005	0.995	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.005	0.995	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.005	0.995	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.005	0.995	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
Q76 Congenital malformations of spine and bony thorax	0.005	0.995	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.005	0.995	0.000
Q76.0 Spina bifida occulta	0.005	0.995	0.000
Z63.5 Disruption of family by separation and divorce	0.000	0.995	0.005
H57.0 Anomalies of pupillary function	0.005	0.995	0.000
C18.9 Colon, unspecified	0.005	0.995	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.005	0.995	0.000
M84.26 Delayed union of fracture (Lower leg)	0.004	0.995	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.004	0.995	0.000
Q21.0 Ventricular septal defect	0.004	0.996	0.000
Z63.9 Problem related to primary support group, unspecified	0.000	0.996	0.004
Z63.3 Absence of family member	0.000	0.996	0.004
Z63.2 Inadequate family support	0.000	0.996	0.004
Z63.1 Problems in relationship with parents and in-laws	0.000	0.996	0.004
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.004	0.996	0.000
H10.9 Conjunctivitis, unspecified	0.004	0.996	0.000
R26.3 Immobility	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
Q27.3 Peripheral arteriovenous malformation	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
Q76.5 Cervical rib	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
Z63.6 Dependent relative needing care at home	0.000	0.996	0.004
M89.9 Disorder of bone, unspecified	0.000	0.996	0.004
Q76.1 Klippel-Feil syndrome	0.004	0.996	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.996	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.996	0.000
Q76.7 Congenital malformation of sternum	0.004	0.996	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.996	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.996	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.996	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
R06.8 Other and unspecified abnormalities of breathing	0.004	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
M21.3 Wrist or foot drop (acquired)	0.004	0.996	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
N48.0 Leukoplakia of penis	0.004	0.996	0.000
Z63.0 Problems in relationship with spouse or partner	0.000	0.996	0.003
Q22.5 Ebstein's anomaly	0.003	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.003	0.997	0.000
M89.98 Disorder of bone, unspecified (Other)	0.000	0.997	0.003
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.997	0.003
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
Z63.8 Other specified problems related to primary support group	0.000	0.997	0.003
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.997	0.003
Q67.6 Pectus excavatum	0.003	0.997	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.997	0.003
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.003	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.003	0.997	0.000
Q21.2 Atrioventricular septal defect	0.003	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.003	0.997	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
O02.1 Missed abortion	0.000	0.997	0.003
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.997	0.003
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
H55-H59 Other disorders of eye and adnexa	0.003	0.997	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.003	0.997	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.003	0.997	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.003	0.997	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.003	0.997	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.003	0.997	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.003	0.997	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.003	0.997	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.003	0.997	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.997	0.003
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
H10 Conjunctivitis	0.003	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
C67.0 Trigone of bladder	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Y89.9 Sequelae of unspecified external cause	0.000	0.997	0.003
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
C67.4 Posterior wall of bladder	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.997	0.003
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.997	0.000
Q77.5 Diastrophic dysplasia	0.002	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.997	0.000
Q77.2 Short rib syndrome	0.002	0.997	0.000
Q77.1 Thanatophoric short stature	0.002	0.997	0.000
Q77.0 Achondrogenesis	0.002	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.997	0.003
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.002	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.997	0.002
Q24.0 Dextrocardia	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.002	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Q69.9 Polydactyly, unspecified	0.002	0.997	0.000
Q69.2 Accessory toe(s)	0.002	0.997	0.000
Q69.1 Accessory thumb(s)	0.002	0.997	0.000
Q69.0 Accessory finger(s)	0.002	0.997	0.000
Q70.9 Syndactyly, unspecified	0.002	0.997	0.000
Q70.4 Polysyndactyly	0.002	0.997	0.000
Q70.3 Webbed toes	0.002	0.997	0.000
Q70.2 Fused toes	0.002	0.997	0.000
Q70.1 Webbed fingers	0.002	0.997	0.000
Q70.0 Fused fingers	0.002	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.997	0.000
Q71.6 Lobster-claw hand	0.002	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.997	0.000
Q72.7 Split foot	0.002	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.997	0.000
Q75.3 Macrocephaly	0.002	0.997	0.000
Q75.2 Hypertelorism	0.002	0.997	0.000
Q75.1 Craniofacial dysostosis	0.002	0.997	0.000
Q75.0 Craniosynostosis	0.002	0.997	0.000
R26.0 Ataxic gait	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
L85.8 Other specified epidermal thickening	0.000	0.997	0.003
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.997	0.002
J39.2 Other diseases of pharynx	0.000	0.997	0.003
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.997	0.000
Q20.4 Double inlet ventricle	0.002	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.997	0.000
Q20.2 Double outlet left ventricle	0.002	0.997	0.000
Q20.1 Double outlet right ventricle	0.002	0.997	0.000
Q20.0 Common arterial trunk	0.002	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.1 Persistent left superior vena cava	0.002	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Q24.6 Congenital heart block	0.002	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.003	0.997	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.997	0.003
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.997	0.000
Q78.6 Multiple congenital exostoses	0.002	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.997	0.000
Q78.4 Enchondromatosis	0.002	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.997	0.000
Q78.2 Osteopetrosis	0.002	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.997	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.003	0.997	0.000
H10.8 Other conjunctivitis	0.002	0.997	0.000
Q21.1 Atrial septal defect	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.997	0.000
Q24.2 Cor triatriatum	0.002	0.997	0.000
Q24.1 Levocardia	0.002	0.997	0.000
Q35 Cleft palate	0.002	0.997	0.000
Y89 Sequelae of other external causes	0.000	0.997	0.002
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.998	0.002
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.002
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.998	0.002
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
L89 Decubitus ulcer	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.002	0.998	0.000
M19.0 Primary arthrosis of other joints	0.000	0.998	0.002
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
R26 Abnormalities of gait and mobility	0.002	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
H10.5 Blepharoconjunctivitis	0.002	0.998	0.000
H10.3 Acute conjunctivitis, unspecified	0.002	0.998	0.000
H10.2 Other acute conjunctivitis	0.002	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.002	0.998	0.000
H10.0 Mucopurulent conjunctivitis	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
M54.1 Radiculopathy	0.002	0.998	0.000
Q35.9 Cleft palate, unspecified	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
Q38.1 Ankyloglossia	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.998	0.002
L81.4 Other melanin hyperpigmentation	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.001	0.998	0.002
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.998	0.002
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.998	0.002
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.998	0.000
Q38.2 Macroglossia	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.998	0.000
M83 Adult osteomalacia	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
C67.1 Dome of bladder	0.002	0.998	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
Q35.8 (Cleft palate, unspecified, bilateral)	0.002	0.998	0.000
Q35.7 Cleft uvula	0.002	0.998	0.000
Q35.6 Cleft palate, medial	0.002	0.998	0.000
Q35.5 Cleft hard palate with cleft soft palate	0.002	0.998	0.000
Q35.4 (Cleft hard palate with cleft soft palate, bilateral)	0.002	0.998	0.000
Q35.3 Cleft soft palate	0.002	0.998	0.000
Q35.2 (Cleft soft palate, bilateral)	0.002	0.998	0.000
Q35.1 Cleft hard palate	0.002	0.998	0.000
Q35.0 (Cleft hard palate, bilateral)	0.002	0.998	0.000
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
Y89.1 Sequelae of war operations	0.000	0.998	0.002
Y89.0 Sequelae of legal intervention	0.000	0.998	0.002
M82 Osteoporosis in diseases classified elsewhere	0.001	0.998	0.001
C67.3 Anterior wall of bladder	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.002	0.998	0.000
M89.5 Osteolysis	0.000	0.998	0.002
Q31.3 Laryngocele	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations