TreeWAS – Variant ID: rs10794657

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E23 Hypofunction and other disorders of pituitary gland	0.000	0.907	0.093
E27 Other disorders of adrenal gland	0.000	0.908	0.092
E23.0 Hypopituitarism	0.000	0.908	0.092
E20-E35 Disorders of other endocrine glands	0.000	0.912	0.088
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.913	0.087
E27.9 Disorder of adrenal gland, unspecified	0.000	0.915	0.085
E23.2 Diabetes insipidus	0.000	0.917	0.083
E23.7 Disorder of pituitary gland, unspecified	0.000	0.922	0.078
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.923	0.077
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.924	0.075
E27.2 Addisonian crisis	0.000	0.928	0.072
E21.0 Primary hyperparathyroidism	0.000	0.928	0.072
E24 Cushing's syndrome	0.000	0.928	0.072
E27.1 Primary adrenocortical insufficiency	0.000	0.929	0.071
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.932	0.068
E27.8 Other specified disorders of adrenal gland	0.000	0.932	0.068
E23.1 Drug-induced hypopituitarism	0.000	0.933	0.067
E27.5 Adrenomedullary hyperfunction	0.000	0.934	0.066
E27.0 Other adrenocortical overactivity	0.000	0.934	0.066
E25 Adrenogenital disorders	0.000	0.934	0.065
E34 Other endocrine disorders	0.000	0.935	0.065
E32 Diseases of thymus	0.000	0.936	0.064
E29 Testicular dysfunction	0.000	0.936	0.064
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.936	0.063
E30 Disorders of puberty, not elsewhere classified	0.000	0.936	0.063
E23.6 Other disorders of pituitary gland	0.000	0.938	0.062
E24.9 Cushing's syndrome, unspecified	0.000	0.940	0.060
E21.4 Other specified disorders of parathyroid gland	0.000	0.941	0.059
E28 Ovarian dysfunction	0.000	0.942	0.058
E26 Hyperaldosteronism	0.000	0.943	0.057
E31 Polyglandular dysfunction	0.000	0.943	0.057
E34.0 Carcinoid syndrome	0.000	0.944	0.056
E24.0 Pituitary-dependent Cushing's disease	0.000	0.945	0.055
E21.2 Other hyperparathyroidism	0.000	0.945	0.055
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.946	0.054
E20 Hypoparathyroidism	0.000	0.947	0.053
E22 Hyperfunction of pituitary gland	0.000	0.947	0.053
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.948	0.052
E24.3 Ectopic ACTH syndrome	0.000	0.948	0.052
E24.1 Nelson's syndrome	0.000	0.948	0.052
E24.8 Other Cushing's syndrome	0.000	0.949	0.050
E24.2 Drug-induced Cushing's syndrome	0.000	0.950	0.049
E29.9 Testicular dysfunction, unspecified	0.000	0.951	0.049
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.951	0.049
E32.9 Disease of thymus, unspecified	0.000	0.953	0.047
E25.9 Adrenogenital disorder, unspecified	0.000	0.953	0.047
E25.8 Other adrenogenital disorders	0.000	0.953	0.047
E21.3 Hyperparathyroidism, unspecified	0.000	0.953	0.047
E34.5 Androgen resistance syndrome	0.000	0.953	0.047
E34.4 Constitutional tall stature	0.000	0.953	0.047
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.953	0.047
E34.1 Other hypersecretion of intestinal hormones	0.000	0.953	0.047
E32.1 Abscess of thymus	0.000	0.954	0.046
E32.0 Persistent hyperplasia of thymus	0.000	0.954	0.046
E29.8 Other testicular dysfunction	0.000	0.954	0.046
E29.0 Testicular hyperfunction	0.000	0.954	0.046
E34.8 Other specified endocrine disorders	0.000	0.954	0.046
E30.9 Disorder of puberty, unspecified	0.000	0.954	0.046
E30.8 Other disorders of puberty	0.000	0.954	0.046
E30.1 Precocious puberty	0.000	0.954	0.046
E30.0 Delayed puberty	0.000	0.954	0.046
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.954	0.046
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.954	0.046
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.954	0.046
E32.8 Other diseases of thymus	0.000	0.954	0.045
E26.9 Hyperaldosteronism, unspecified	0.000	0.957	0.043
E29.1 Testicular hypofunction	0.000	0.957	0.043
E28.9 Ovarian dysfunction, unspecified	0.000	0.958	0.042
E28.8 Other ovarian dysfunction	0.000	0.958	0.042
E28.1 Androgen excess	0.000	0.958	0.042
E28.0 Oestrogen excess	0.000	0.958	0.042
E34.3 Short stature, not elsewhere classified	0.000	0.958	0.042
E26.8 Other hyperaldosteronism	0.000	0.959	0.041
E26.1 Secondary hyperaldosteronism	0.000	0.959	0.041
E31.9 Polyglandular dysfunction, unspecified	0.000	0.959	0.041
E31.8 Other polyglandular dysfunction	0.000	0.959	0.041
E31.1 Polyglandular hyperfunction	0.000	0.959	0.041
E34.9 Endocrine disorder, unspecified	0.000	0.959	0.041
E28.3 Primary ovarian failure	0.000	0.959	0.041
E22.1 Hyperprolactinaemia	0.000	0.961	0.039
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.962	0.038
E20.0 Idiopathic hypoparathyroidism	0.000	0.962	0.038
E22.8 Other hyperfunction of pituitary gland	0.000	0.962	0.038
E28.2 Polycystic ovarian syndrome	0.000	0.962	0.038
E20.9 Hypoparathyroidism, unspecified	0.000	0.964	0.036
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.965	0.035
E20.8 Other hypoparathyroidism	0.000	0.966	0.034
E20.1 Pseudohypoparathyroidism	0.000	0.966	0.034
E31.0 Autoimmune polyglandular failure	0.000	0.966	0.034
E26.0 Primary hyperaldosteronism	0.000	0.968	0.031
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.001	0.969	0.031
E22.0 Acromegaly and pituitary gigantism	0.000	0.971	0.029
R06.8 Other and unspecified abnormalities of breathing	0.000	0.983	0.017
C15.9 Oesophagus, unspecified	0.016	0.984	0.000
H00.1 Chalazion	0.000	0.985	0.015
B18.2 Chronic viral hepatitis C	0.000	0.987	0.013
C15 Malignant neoplasm of oesophagus	0.013	0.987	0.000
C15.5 Lower third of oesophagus	0.012	0.988	0.000
J15.2 Pneumonia due to staphylococcus	0.000	0.990	0.010
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.990	0.010
C15.3 Upper third of oesophagus	0.010	0.990	0.000
C15.1 Thoracic part of oesophagus	0.010	0.990	0.000
C15.4 Middle third of oesophagus	0.010	0.990	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.990	0.010
C15.0 Cervical part of oesophagus	0.009	0.991	0.000
C15.8 Overlapping lesion of oesophagus	0.009	0.991	0.000
C15.2 Abdominal part of oesophagus	0.009	0.991	0.000
J15.4 Pneumonia due to other streptococci	0.000	0.991	0.008
J15.9 Bacterial pneumonia, unspecified	0.000	0.992	0.008
J15.5 Pneumonia due to Escherichia coli	0.000	0.992	0.008
S22.40 Multiple fractures of ribs (closed)	0.000	0.992	0.008
J15.3 Pneumonia due to streptococcus, group B	0.000	0.993	0.007
J15.1 Pneumonia due to Pseudomonas	0.000	0.993	0.007
B18 Chronic viral hepatitis	0.000	0.993	0.007
N99.3 Prolapse of vaginal vault after hysterectomy	0.007	0.993	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.993	0.007
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.993	0.007
G93.3 Postviral fatigue syndrome	0.007	0.993	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.006	0.994	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.006	0.994	0.000
F60.9 Personality disorder, unspecified	0.006	0.994	0.000
S22.4 Multiple fractures of ribs	0.000	0.994	0.006
D25.2 Subserosal leiomyoma of uterus	0.000	0.994	0.006
B18.9 Chronic viral hepatitis, unspecified	0.000	0.994	0.005
G93.2 Benign intracranial hypertension	0.005	0.995	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.005	0.995	0.000
B18.8 Other chronic viral hepatitis	0.000	0.995	0.005
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.995	0.005
J15.8 Other bacterial pneumonia	0.000	0.995	0.005
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.995	0.005
G93.8 Other specified disorders of brain	0.005	0.995	0.000
N99.5 Malfunction of external stoma of urinary tract	0.005	0.995	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.005	0.995	0.000
H00 Hordeolum and chalazion	0.000	0.995	0.005
N99.2 Postprocedural adhesions of vagina	0.005	0.995	0.000
G93 Other disorders of brain	0.005	0.995	0.000
N99.1 Postprocedural urethral stricture	0.005	0.995	0.000
K01.1 Impacted teeth	0.000	0.995	0.005
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.995	0.005
S22.41 Multiple fractures of ribs (open)	0.000	0.995	0.004
F60 Specific personality disorders	0.004	0.996	0.000
S22.2 Fracture of sternum	0.000	0.996	0.004
S22.3 Fracture of rib	0.000	0.996	0.004
N99.0 Postprocedural renal failure	0.004	0.996	0.000
S22.20 Fracture of sternum (closed)	0.000	0.996	0.004
D09.0 Bladder	0.004	0.996	0.000
F60.3 Emotionally unstable personality disorder	0.004	0.996	0.000
G93.5 Compression of brain	0.004	0.996	0.000
S22.30 Fracture of rib (closed)	0.000	0.996	0.004
L30.9 Dermatitis, unspecified	0.000	0.996	0.004
S22.0 Fracture of thoracic vertebra	0.000	0.996	0.004
F60.6 Anxious [avoidant] personality disorder	0.004	0.996	0.000
G93.7 Reye's syndrome	0.004	0.996	0.000
F60.8 Other specific personality disorders	0.004	0.996	0.000
R09.1 Pleurisy	0.000	0.996	0.004
F60.0 Paranoid personality disorder	0.004	0.996	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.996	0.003
S22.8 Fracture of other parts of bony thorax	0.000	0.996	0.003
G93.1 Anoxic brain damage, not elsewhere classified	0.004	0.996	0.000
F41.2 Mixed anxiety and depressive disorder	0.004	0.996	0.000
G93.9 Disorder of brain, unspecified	0.003	0.996	0.000
F60.4 Histrionic personality disorder	0.003	0.996	0.000
F60.1 Schizoid personality disorder	0.003	0.996	0.000
S43.0 Dislocation of shoulder joint	0.003	0.996	0.000
G58.9 Mononeuropathy, unspecified	0.000	0.997	0.003
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
S22.5 Flail chest	0.000	0.997	0.003
S22.21 Fracture of sternum (open)	0.000	0.997	0.003
S22.1 Multiple fractures of thoracic spine	0.000	0.997	0.003
S22.31 Fracture of rib (open)	0.000	0.997	0.003
F60.5 Anankastic personality disorder	0.003	0.997	0.000
M13.94 Arthritis, unspecified (Hand)	0.000	0.997	0.003
S22.01 Fracture of thoracic vertebra (open)	0.000	0.997	0.003
F60.2 Dissocial personality disorder	0.003	0.997	0.000
J14 Pneumonia due to Haemophilus influenzae	0.000	0.997	0.003
Z95.0 Presence of cardiac pacemaker	0.000	0.997	0.003
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.997	0.003
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.997	0.003
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.997	0.003
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.997	0.003
B44.9 Aspergillosis, unspecified	0.000	0.997	0.003
J09-J18 Influenza and pneumonia	0.000	0.997	0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.003	0.997	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
F60.7 Dependent personality disorder	0.003	0.997	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.997	0.003
N99-N99 Other disorders of the genitourinary system	0.003	0.997	0.000
S22.51 Flail chest (open)	0.000	0.997	0.003
C34.1 Upper lobe, bronchus or lung	0.000	0.997	0.003
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.997	0.002
F60-F69 Disorders of adult personality and behaviour	0.003	0.997	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.997	0.003
G93.4 Encephalopathy, unspecified	0.002	0.997	0.000
G93.0 Cerebral cysts	0.002	0.997	0.000
G93.6 Cerebral oedema	0.002	0.997	0.000
D04.5 Skin of trunk	0.000	0.997	0.003
B44.1 Other pulmonary aspergillosis	0.000	0.997	0.003
F64 Gender identity disorders	0.002	0.997	0.000
J11 Influenza, virus not identified	0.000	0.997	0.002
S22.50 Flail chest (closed)	0.000	0.997	0.002
G61.0 Guillain-Barre syndrome	0.002	0.997	0.000
J17 Pneumonia in diseases classified elsewhere	0.000	0.997	0.002
F69 Unspecified disorder of adult personality and behaviour	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.998	0.002
J17.2 Pneumonia in mycoses	0.000	0.998	0.002
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
F64.0 Transsexualism	0.002	0.998	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.000	0.998	0.002
B15-B19 Viral hepatitis	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.002	0.998	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.998	0.002
F68 Other disorders of adult personality and behaviour	0.002	0.998	0.000
J09 Influenza due to certain identified influenza virus	0.000	0.998	0.002
S43.1 Dislocation of acromioclavicular joint	0.002	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.998	0.002
B44 Aspergillosis	0.000	0.998	0.002
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.002	0.998	0.000
F65 Disorders of sexual preference	0.002	0.998	0.000
F63 Habit and impulse disorders	0.002	0.998	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.002	0.998	0.000
S00.0 Superficial injury of scalp	0.002	0.998	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.002	0.998	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.998	0.002
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.998	0.002
K01 Embedded and impacted teeth	0.000	0.998	0.002
F61 Mixed and other personality disorders	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.998	0.002
F64.9 Gender identity disorder, unspecified	0.002	0.998	0.000
F64.8 Other gender identity disorders	0.002	0.998	0.000
F64.2 Gender identity disorder of childhood	0.002	0.998	0.000
F64.1 Dual-role transvestism	0.002	0.998	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.002	0.998	0.000
J12 Viral pneumonia, not elsewhere classified	0.000	0.998	0.002
J17.8 Pneumonia in other diseases classified elsewhere	0.000	0.998	0.002
J17.3 Pneumonia in parasitic diseases	0.000	0.998	0.002
B15 Acute hepatitis A	0.000	0.998	0.002
B19 Unspecified viral hepatitis	0.000	0.998	0.002
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.998	0.002
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.998	0.002
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.002	0.998	0.000
J16.8 Pneumonia due to other specified infectious organisms	0.000	0.998	0.002
J16.0 Chlamydial pneumonia	0.000	0.998	0.002
J17.1 Pneumonia in viral diseases classified elsewhere	0.000	0.998	0.002
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.002	0.998	0.000
F68.8 Other specified disorders of adult personality and behaviour	0.002	0.998	0.000
F68.0 Elaboration of physical symptoms for psychological reasons	0.002	0.998	0.000
J11.8 Influenza with other manifestations, virus not identified	0.000	0.998	0.002
R52.2 Other chronic pain	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
B44.7 Disseminated aspergillosis	0.000	0.998	0.002
B44.2 Tonsillar aspergillosis	0.000	0.998	0.002
B44.0 Invasive pulmonary aspergillosis	0.000	0.998	0.002
F63.9 Habit and impulse disorder, unspecified	0.002	0.998	0.000
F63.8 Other habit and impulse disorders	0.002	0.998	0.000
F63.3 Trichotillomania	0.002	0.998	0.000
F63.2 Pathological stealing [kleptomania]	0.002	0.998	0.000
F63.1 Pathological fire-setting [pyromania]	0.002	0.998	0.000
F63.0 Pathological gambling	0.002	0.998	0.000
F65.9 Disorder of sexual preference, unspecified	0.002	0.998	0.000
F65.8 Other disorders of sexual preference	0.002	0.998	0.000
F65.6 Multiple disorders of sexual preference	0.002	0.998	0.000
F65.5 Sadomasochism	0.002	0.998	0.000
F65.4 Paedophilia	0.002	0.998	0.000
F65.3 Voyeurism	0.002	0.998	0.000
F65.2 Exhibitionism	0.002	0.998	0.000
F65.1 Fetishistic transvestism	0.002	0.998	0.000
F65.0 Fetishism	0.002	0.998	0.000
F66.9 Psychosexual development disorder, unspecified	0.002	0.998	0.000
F66.8 Other psychosexual development disorders	0.002	0.998	0.000
F66.2 Sexual relationship disorder	0.002	0.998	0.000
F66.1 Egodystonic sexual orientation	0.002	0.998	0.000
F66.0 Sexual maturation disorder	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.998	0.002
B15.9 Hepatitis A without hepatic coma	0.000	0.998	0.002
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
F62.8 Other enduring personality changes	0.002	0.998	0.000
F62.1 Enduring personality change after psychiatric illness	0.002	0.998	0.000
F62.0 Enduring personality change after catastrophic experience	0.002	0.998	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.000	0.998	0.002
B19.9 Unspecified viral hepatitis without coma	0.000	0.998	0.002
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
B44.8 Other forms of aspergillosis	0.000	0.998	0.002
D04.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
J11.0 Influenza with pneumonia, virus not identified	0.000	0.998	0.001
K01.0 Embedded teeth	0.000	0.998	0.002
F62.9 Enduring personality change, unspecified	0.002	0.998	0.000
J12.8 Other viral pneumonia	0.000	0.998	0.002
J12.3 Human metapneumovirus pneumonia	0.000	0.998	0.002
J12.0 Adenoviral pneumonia	0.000	0.998	0.002
J10 Influenza due to identified influenza virus	0.000	0.998	0.002
B15.0 Hepatitis A with hepatic coma	0.000	0.998	0.002
T17.2 Foreign body in pharynx	0.002	0.998	0.000
B19.0 Unspecified viral hepatitis with coma	0.000	0.998	0.002
B16 Acute hepatitis B	0.000	0.998	0.002
D09 Carcinoma in situ of other and unspecified sites	0.002	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.998	0.002
H05.2 Exophthalmic conditions	0.000	0.998	0.002
J12.1 Respiratory syncytial virus pneumonia	0.000	0.998	0.001
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.998	0.002
R23.8 Other and unspecified skin changes	0.000	0.998	0.002
S32.1 Fracture of sacrum	0.000	0.998	0.002
C69.3 Choroid	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
W18.5 Trade and service area	0.000	0.998	0.002
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
D04.4 Skin of scalp and neck	0.000	0.998	0.002
J12.2 Parainfluenza virus pneumonia	0.000	0.998	0.001
S32 Fracture of lumbar spine and pelvis	0.000	0.998	0.002
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.000	0.998	0.002
S32.4 Fracture of acetabulum	0.000	0.998	0.002
L30 Other dermatitis	0.000	0.998	0.002
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
X78.0 Home	0.000	0.998	0.002
D04 Carcinoma in situ of skin	0.000	0.998	0.002
G61.1 Serum neuropathy	0.001	0.998	0.000
J12.9 Viral pneumonia, unspecified	0.000	0.998	0.001
S32.5 Fracture of pubis	0.000	0.998	0.002
J81 Pulmonary oedema	0.000	0.998	0.002
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.998	0.001
J69.0 Pneumonitis due to food and vomit	0.000	0.998	0.002
L30.8 Other specified dermatitis	0.000	0.998	0.002
O26.8 Other specified pregnancy-related conditions	0.002	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
H47.0 Disorders of optic nerve, not elsewhere classified	0.002	0.998	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.998	0.002
J10.8 Influenza with other manifestations, influenza virus identified	0.000	0.998	0.001
S92.0 Fracture of calcaneus	0.000	0.998	0.002
B17 Other acute viral hepatitis	0.000	0.998	0.001
Q24 Other congenital malformations of heart	0.000	0.998	0.002
C50.5 Lower-outer quadrant of breast	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.001	0.998	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.000	0.998	0.002
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.998	0.002
U80.0 Penicillin resistant agent	0.000	0.998	0.002
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.001	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.998	0.001
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.998	0.001
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.998	0.001
D04.6 Skin of upper limb, including shoulder	0.000	0.998	0.001
D09.9 Carcinoma in situ, unspecified	0.001	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.001	0.998	0.000
D09.2 Eye	0.001	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.001
S32.11 Fracture of sacrum (open)	0.000	0.998	0.001
S30.2 Contusion of external genital organs	0.000	0.998	0.001
J80 Adult respiratory distress syndrome	0.000	0.998	0.001
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.001
M00.9 Pyogenic arthritis, unspecified	0.000	0.998	0.001
N36.8 Other specified disorders of urethra	0.001	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.001
Q24.6 Congenital heart block	0.000	0.998	0.001
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.001
R23.2 Flushing	0.000	0.998	0.001
S92.01 Fracture of calcaneus (open)	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.000	0.999	0.001
R23.0 Cyanosis	0.000	0.999	0.001
S20.2 Contusion of thorax	0.000	0.999	0.001
U80 Agent resistant to penicillin and related antibiotics	0.000	0.999	0.001
S32.41 Fracture of acetabulum (open)	0.000	0.999	0.001
D26.1 Corpus uteri	0.000	0.999	0.001
J10.0 Influenza with pneumonia, influenza virus identified	0.000	0.999	0.001
L30.5 Pityriasis alba	0.000	0.999	0.001
L30.2 Cutaneous autosensitisation	0.000	0.999	0.001
O14.0 Moderate preeclampsia	0.000	0.999	0.001
U80.1 Methicillin resistant agent	0.000	0.999	0.001
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.999	0.001
S32.51 Fracture of pubis (open)	0.000	0.999	0.001
D04.8 Skin of other sites	0.000	0.999	0.001
D09.1 Other and unspecified urinary organs	0.001	0.999	0.000
S32.2 Fracture of coccyx	0.000	0.999	0.001
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.000	0.999	0.001
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.000	0.999	0.001
D04.2 Skin of ear and external auricular canal	0.000	0.999	0.001
J69.8 Pneumonitis due to other solids and liquids	0.000	0.999	0.001
L30.4 Erythema intertrigo	0.000	0.999	0.001
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.999	0.001
R06.2 Wheezing	0.000	0.999	0.001
R23.3 Spontaneous ecchymoses	0.000	0.999	0.001
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
S36.40 Injury of small intestine (without open wound into cavity)	0.000	0.999	0.001
D04.0 Skin of lip	0.000	0.999	0.001
L30.0 Nummular dermatitis	0.000	0.999	0.001
Q24.4 Congenital subaortic stenosis	0.000	0.999	0.001
Q24.0 Dextrocardia	0.000	0.999	0.001
S32.3 Fracture of ilium	0.000	0.999	0.001
J84 Other interstitial pulmonary diseases	0.000	0.999	0.001
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.999	0.001
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.999	0.001
D04.9 Skin, unspecified	0.000	0.999	0.001
Q24.3 Pulmonary infundibular stenosis	0.000	0.999	0.001
Q24.2 Cor triatriatum	0.000	0.999	0.001
Q24.1 Levocardia	0.000	0.999	0.001
R90.0 Intracranial space-occupying lesion	0.000	0.999	0.001
R06 Abnormalities of breathing	0.000	0.999	0.001
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.999	0.001
B17.8 Other specified acute viral hepatitis	0.000	0.999	0.001
D04.1 Skin of eyelid, including canthus	0.000	0.999	0.001
K74.6 Other and unspecified cirrhosis of liver	0.000	0.999	0.001
S30.1 Contusion of abdominal wall	0.000	0.999	0.001
B17.2 Acute hepatitis E	0.000	0.999	0.001
Q27.3 Peripheral arteriovenous malformation	0.000	0.999	0.001
Q85.9 Phakomatosis, unspecified	0.000	0.999	0.001
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.999	0.001
R23 Other skin changes	0.000	0.999	0.001
M00.98 Pyogenic arthritis, unspecified (Other)	0.000	0.999	0.001
B17.9 Acute viral hepatitis, unspecified	0.000	0.999	0.001
H05.9 Disorder of orbit, unspecified	0.000	0.999	0.001
L30.1 Dyshidrosis [pompholyx]	0.000	0.999	0.001
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
S36.4 Injury of small intestine	0.000	0.999	0.001
E16.2 Hypoglycaemia, unspecified	0.000	0.999	0.001
J69 Pneumonitis due to solids and liquids	0.000	0.999	0.001
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.999	0.001
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.000	0.999	0.001
M00.94 Pyogenic arthritis, unspecified (Hand)	0.000	0.999	0.001
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.999	0.001
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
S32.21 Fracture of coccyx (open)	0.000	0.999	0.001
S32.31 Fracture of ilium (open)	0.000	0.999	0.001
S92.51 Fracture of other toe (open)	0.000	0.999	0.001
J84.0 Alveolar and parietoalveolar conditions	0.000	0.999	0.001
S99.8 Other specified injuries of ankle and foot	0.000	0.999	0.001
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.999	0.001
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.999	0.001
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.000	0.999	0.001
S36.41 Injury of small intestine (with open wound into cavity)	0.000	0.999	0.001
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.999	0.001
J84.8 Other specified interstitial pulmonary diseases	0.000	0.999	0.001
L30.3 Infective dermatitis	0.000	0.999	0.001
N36.2 Urethral caruncle	0.001	0.999	0.000
R06.7 Sneezing	0.000	0.999	0.001
R06.3 Periodic breathing	0.000	0.999	0.001
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.000	0.999	0.001
S51.0 Open wound of elbow	0.000	0.999	0.001
S92.5 Fracture of other toe	0.000	0.999	0.001
Z93.0 Tracheostomy status	0.000	0.999	0.001
G58 Other mononeuropathies	0.000	0.999	0.001
H05 Disorders of orbit	0.000	0.999	0.001
S92.50 Fracture of other toe (closed)	0.000	0.999	0.001
S90.8 Other superficial injuries of ankle and foot	0.000	0.999	0.001
X19.9 Unspecified place	0.000	0.999	0.001
Q27 Other congenital malformations of peripheral vascular system	0.000	0.999	0.001
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
S32.20 Fracture of coccyx (closed)	0.000	0.999	0.001
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.999	0.001
D28.2 Uterine tubes and ligaments	0.000	0.999	0.001
E04.2 Non-toxic multinodular goitre	0.000	0.999	0.001
N30.2 Other chronic cystitis	0.001	0.999	0.000
R50.0 Fever with chills	0.001	0.999	0.000
S90.1 Contusion of toe(s) without damage to nail	0.000	0.999	0.001
Z22.5 Carrier of viral hepatitis	0.000	0.999	0.001
Q28 Other congenital malformations of circulatory system	0.000	0.999	0.001
D28.0 Vulva	0.000	0.999	0.001
O14.1 Severe preeclampsia	0.000	0.999	0.001
O46.8 Other antepartum haemorrhage	0.000	0.999	0.001
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.999	0.001
S93.1 Dislocation of toe(s)	0.000	0.999	0.001
T17.3 Foreign body in larynx	0.001	0.999	0.000
S42.10 Fracture of scapula (closed)	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.001	0.999	0.000
G58.8 Other specified mononeuropathies	0.000	0.999	0.001
G91.9 Hydrocephalus, unspecified	0.000	0.999	0.001
J34.3 Hypertrophy of nasal turbinates	0.000	0.999	0.001
J69.1 Pneumonitis due to oils and essences	0.000	0.999	0.001
O12.0 Gestational oedema	0.000	0.999	0.001
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.001	0.999	0.000
R23.1 Pallor	0.000	0.999	0.001
S90 Superficial injury of ankle and foot	0.000	0.999	0.001
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
S32.30 Fracture of ilium (closed)	0.000	0.999	0.001
D68.9 Coagulation defect, unspecified	0.000	0.999	0.001
F42.9 Obsessive-compulsive disorder, unspecified	0.001	0.999	0.000
H47.2 Optic atrophy	0.001	0.999	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.999	0.001
S99.9 Unspecified injury of ankle and foot	0.000	0.999	0.001
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.999	0.001
R25 Abnormal involuntary movements	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations